tacrine has been researched along with 4-aminopyridine in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (17.39) | 18.7374 |
| 1990's | 18 (78.26) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carlier, PR; Chow, ES; El Yazal, J; Han, Y; Liu, J; Pang, YP | 1 |
| Crul, JF; Martinez-Aguirre, E | 1 |
| Dolezal, V; Tucek, S | 3 |
| Heilbronn, E; Järlebark, L | 1 |
| Braga, MF; Harvey, AL; Rowan, EG | 1 |
| Kojima, J; Obara, S; Sugawara, Y | 1 |
| Chaki, S; Muramatsu, M; Otomo, S | 1 |
| Cook, L; DeNoble, KF; DeNoble, VJ; Johnson, LC; Myers, MJ; Scribner, RM; Spencer, KR | 1 |
| Griffith, WH; Sim, JA | 1 |
| Robbins, J; Sim, JA | 1 |
| Cumming, P; Reiner, PB; Vincent, SR | 1 |
| Buyukuysal, RL; Wurtman, RJ | 1 |
| Chepkova, AN; Doreuli, NV; Skrebitskiĭ, VG | 1 |
| Gibson, GE; Manger, T | 1 |
| Chuang, DM; Ishitani, R; Sunaga, K | 1 |
| Nordberg, A; Xiao, WB; Zhang, X | 1 |
| Gean, PW; Huang, CC; Wang, SJ | 1 |
| Kraliz, D; Singh, S | 1 |
| Farlow, MR; Greig, NH; Lahiri, DK; Nurnberger, JI | 1 |
| Puil, E; Ries, CR | 1 |
| Chen, YH; Chuang, CM; Hsu, HY; Lin, CH; Lin, PL; Tsai, MC; Yang, HY | 1 |
23 other study(ies) available for tacrine and 4-aminopyridine
| Article | Year |
|---|---|
Heterodimeric tacrine-based acetylcholinesterase inhibitors: investigating ligand-peripheral site interactions.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Crystallography, X-Ray; Drug Design; In Vitro Techniques; Ligands; Protein Binding; Rats; Structure-Activity Relationship; Tacrine | 1999 |
Effect of tetrahydroaminoacridine and 4-aminopyridine on recovery from ketamine-diazepam anesthesia in the macacus rhesus monkey.
Topics: 4-Aminopyridine; Acridines; Aminopyridines; Anesthesia, Intravenous; Animals; Diazepam; Electroencephalography; Haplorhini; Ketamine; Macaca mulatta; Tacrine | 1979 |
Investigation of the mechanism of the effect of tacrine (tetrahydroaminoacridine) on the metabolism of acetylcholine and choline in brain cortical prisms.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Cerebral Cortex; Choline; Hemicholinium 3; In Vitro Techniques; Male; Nerve Endings; Paraoxon; Phosphatidylcholines; Phosphorylation; Phosphorylcholine; Rats; Rats, Wistar; Tacrine | 1992 |
Tetrahydroaminoacridine and related compounds interfere with fura-2 and indo-1.
Topics: 4-Aminopyridine; Animals; Dose-Response Relationship, Drug; Drug Interactions; Fura-2; Indoles; Rats; Tacrine | 1992 |
Effects of tacrine, velnacrine (HP029), suronacrine (HP128), and 3,4-diaminopyridine on skeletal neuromuscular transmission in vitro.
Topics: 4-Aminopyridine; Acetylcholine; Acetylcholinesterase; Action Potentials; Amifampridine; Aminoacridines; Animals; Calcium; Chick Embryo; Cholinesterase Inhibitors; Electrophysiology; In Vitro Techniques; Magnesium; Male; Mice; Mice, Inbred BALB C; Motor Endplate; Neuromuscular Junction; Respiratory Muscles; Synaptic Transmission; Tacrine | 1991 |
Negative effects of tacrine (tetrahydroaminoacridine) and methoxytacrine on the metabolism of acetylcholine in brain slices incubated under conditions stimulating neurotransmitter release.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Brain; Choline; Choline O-Acetyltransferase; Histological Techniques; In Vitro Techniques; Neurotransmitter Agents; Potassium; Rats; Tacrine | 1991 |
NIK-247 blocks voltage-dependent ionic currents in crayfish axon.
Topics: 4-Aminopyridine; Aminoquinolines; Animals; Astacoidea; Axons; Cholinesterase Inhibitors; Electrophysiology; Ion Channels; Membrane Potentials; Potassium; Psychotropic Drugs; Tacrine | 1991 |
Positive and negative effects of tacrine (tetrahydroaminoacridine) and methoxytacrine on the metabolism of acetylcholine in brain cortical prisms incubated under "resting" conditions.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Cerebral Cortex; Choline; Cholinesterases; Hemicholinium 3; Histological Techniques; Male; Rats; Rest; Tacrine | 1991 |
Blockade of voltage-dependent 42K efflux from rat brain synaptosome by minaprine and tetrahydroaminoacridine.
Topics: 4-Aminopyridine; Animals; Antidepressive Agents; Brain; Kinetics; Male; Membrane Potentials; Potassium; Potassium Channels; Pyridazines; Rats; Rats, Inbred Strains; Synaptosomes; Tacrine | 1991 |
Comparison of DuP 996, with physostigmine, THA and 3,4-DAP on hypoxia-induced amnesia in rats.
Topics: 4-Aminopyridine; Amnesia; Animals; Avoidance Learning; Hypoxia; Indoles; Male; Oxygen Consumption; Parasympathetic Nervous System; Physostigmine; Pyridines; Rats; Rats, Inbred Strains; Tacrine | 1990 |
Comparison of 4-aminopyridine and tetrahydroaminoacridine on basal forebrain neurons.
Topics: 4-Aminopyridine; Animals; Brain; Cell Membrane; Guinea Pigs; Intracellular Fluid; Membrane Potentials; Neurons; Tacrine | 1990 |
A transient outward current in NG108-15 neuroblastoma x glioma hybrid cells.
Topics: 4-Aminopyridine; Action Potentials; Adrenergic Fibers; Animals; Barium; Calcium; Elapid Venoms; Glioma; Hybrid Cells; Membrane Potentials; Neuroblastoma; Potassium; Potassium Channels; Rats; Tacrine; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Tumor Cells, Cultured | 1990 |
Inhibition of rat brain histamine-N-methyltransferase by 9-amino-1,2,3,4-tetrahydroacridine (THA).
Topics: 4-Aminopyridine; Aminoacridines; Animals; Antineoplastic Agents; Brain; Histamine; Histamine N-Methyltransferase; Injections, Intraperitoneal; Male; Methyltransferases; Physostigmine; Pyrimethamine; Rats; Tacrine | 1990 |
Tetrahydroaminoacridine but not 4-aminopyridine inhibits high-affinity choline uptake in striatal and hippocampal synaptosomes.
Topics: 4-Aminopyridine; Aminoacridines; Aminopyridines; Animals; Choline; Choline O-Acetyltransferase; Corpus Striatum; Hippocampus; Male; Rats; Rats, Inbred Strains; Synaptosomes; Tacrine | 1989 |
[Effects of polymethylene derivatives of 4-aminopyridine on functional properties of hippocampal neurons].
Topics: 4-Aminopyridine; Alzheimer Disease; Aminoacridines; Aminoquinolines; Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Neurons; Rats; Rats, Inbred Strains; Tacrine | 1989 |
Changes in cytosolic free calcium with 1,2,3,4-tetrahydro-5-aminoacridine, 4-aminopyridine and 3,4-diaminopyridine.
Topics: 4-Aminopyridine; Amifampridine; Aminoacridines; Aminopyridines; Animals; Brain; Calcium; Cytosol; In Vitro Techniques; Mice; Synaptosomes; Tacrine | 1988 |
Tetrahydroaminoacridine is neurotrophic and promotes the expression of muscarinic receptor-coupled phosphoinositide turnover in differentiating cerebellar granule cells.
Topics: 4-Aminopyridine; Animals; Carbachol; Cell Survival; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Kinetics; N-Methylaspartate; Neurons; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Tacrine | 1993 |
Effect of in vivo microdialysis of 1,2,3,4-tetrahydro-9-aminoacridine (THA) on the extracellular concentration of acetylcholine in the striatum of anesthetized rats.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Cholinesterase Inhibitors; Corpus Striatum; Dialysis; Male; Physostigmine; Potassium; Rats; Rats, Sprague-Dawley; Tacrine | 1993 |
Investigations on the mechanism of tetrahydro-9-aminoacridine-induced presynaptic inhibition in the rat amygdala.
Topics: 4-Aminopyridine; Alzheimer Disease; Amygdala; Animals; Baclofen; Dose-Response Relationship, Drug; Male; Membrane Potentials; Nifedipine; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tacrine; Time Factors | 1996 |
Selective blockade of the delayed rectifier potassium current by tacrine in Drosophila.
Topics: 4-Aminopyridine; Action Potentials; Animals; Biological Evolution; Calcium Channels; Drosophila melanogaster; Muscles; Parasympathomimetics; Patch-Clamp Techniques; Potassium Channel Blockers; Tacrine | 1997 |
Effects of cholinesterase inhibitors on the secretion of beta-amyloid precursor protein in cell cultures.
Topics: 4-Aminopyridine; Amifampridine; Amyloid beta-Protein Precursor; Animals; Cholinesterase Inhibitors; HeLa Cells; Humans; PC12 Cells; Physostigmine; Rats; Tacrine; Trichlorfon; Tumor Cells, Cultured | 1997 |
Ionic mechanism of isoflurane's actions on thalamocortical neurons.
Topics: 4-Aminopyridine; Action Potentials; Anesthetics, Inhalation; Animals; Baclofen; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Conductivity; Female; GABA Agonists; Glyburide; Hypoglycemic Agents; Isoflurane; Male; Neurons; Parasympathomimetics; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Synapses; Tacrine; Tetraethylammonium; Tetrodotoxin; Thalamus | 1999 |
Action potential bursts in central snail neurons elicited by procaine: roles of ionic currents.
Topics: 4-Aminopyridine; Action Potentials; Anesthetics, Local; Animals; Calcium Channels; Dose-Response Relationship, Drug; Estrenes; Ion Channels; Models, Animal; Neurons; Patch-Clamp Techniques; Potassium Channels; Procaine; Pyrrolidinones; Snails; Sodium Channels; Tacrine; Tetraethylammonium; Type C Phospholipases | 2010 |