Page last updated: 2024-09-04

tac 278 and fluorouracil

tac 278 has been researched along with fluorouracil in 7 studies

Compound Research Comparison

Studies
(tac 278)
Trials
(tac 278)
Recent Studies (post-2010)
(tac 278)
Studies
(fluorouracil)
Trials
(fluorouracil)
Recent Studies (post-2010) (fluorouracil)
110045,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomytac 278 (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Isobe, K; Iwase, H; Kimura, K; Kuwabara, T; Sato, A; Suga, S; Takada, T; Yokoyama, Y; Yoshida, Y1
Kimura, K; Suga, S1
Majima, H; Sueyoshi, K1
Koyama, Y1
Arimori, S; Furue, H; Ikenaga, M; Iketa, T; Komita, T; Nagao, T; Ohki, S; Satoh, H; Watanabe, K; Yamamoto, S1

Other Studies

7 other study(ies) available for tac 278 and fluorouracil

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Studies on the designing of chemotherapy for gastric cancer in man, based on the tumor tissue concentration of anticancer agents.
    Gastroenterologia Japonica, 1982, Volume: 17, Issue:4

    Topics: Antineoplastic Agents; Floxuridine; Fluorouracil; Gastric Mucosa; Humans; Stomach Neoplasms; Tegafur

1982
[Pharmacological and pharmacodynamic aspects of cancer chemotherapy, with special reference to 5-fluorouracil and its derivatives].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Floxuridine; Fluorouracil; Humans; Kinetics; Neoplasms; Tegafur; Uracil

1982
[Cerebrospinal fluid distributions of systemically administered fluorinated pyrimidines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Ependymoma; Female; Fluorouracil; Glioblastoma; Humans; Male; Middle Aged; Tegafur

1983
[Phase II study of a new fluorinated pyrimidine, ethyl (+/-)-t-6-butoxy-5-fluoro-2, 4-dioxohexahydropyrimidine-r-5-carboxylate (TAC-278)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:10

    Topics: Antineoplastic Agents; Breast Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Lung Neoplasms; Male; Neoplasms

1982
[Phase I clinical study of a new fluorinated pyrimidine antineoplastic agent, TAC-278].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Drug Tolerance; Female; Fluorouracil; Humans; Kinetics; Male; Middle Aged; Neoplasms

1982
[TAC-278. A new 5-FU derivative, by the oral route for its efficacy and safety in 36 patients with advanced cancers].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:4

    Topics: Adult; Aged; Blood Platelets; Drug Evaluation; Female; Fluorouracil; Humans; Intestinal Neoplasms; Intestine, Large; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasms; Stomach Neoplasms

1982