Compounds > t-kinin
Page last updated: 2024-09-03

t-kinin and indomethacin

t-kinin has been researched along with indomethacin in 4 studies

Compound Research Comparison

Studies
(t-kinin)		Trials
(t-kinin)		Recent Studies (post-2010)
(t-kinin)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
430029,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomyt-kinin (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carmignani, M; Porcelli, G; Volpe, AR1
Cohen, RH; Perl, ER1
Conlon, JM; Gao, XP; Mayhan, WG; Rennard, SI; Rubinstein, I1
Gao, X; Greenbaum, LM; Stewart, JM; Vavrek, RJ1

Other Studies

4 other study(ies) available for t-kinin and indomethacin

ArticleYear
Interactions of T-kinin (Ile-Ser-bradykinin) with neurogenic, autacoidal and effector systems in affecting cardiovascular function.
    Agents and actions. Supplements, 1992, Volume: 38 ( Pt 3)

    Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Bucladesine; Diastole; Heart Rate; Hexamethonium; Hexamethonium Compounds; Histamine; Hydrocortisone; Indomethacin; Isoproterenol; Papaverine; Rats; Systole; Tyramine; Vagotomy; Verapamil

1992
Chemical factors in the sensitization of cutaneous nociceptors.
    Progress in brain research, 1988, Volume: 74

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Bradykinin; Indomethacin; Nociceptors; Prostaglandins E; Pyrazoles; Rabbits; Skin; Substance P

1988
Mechanisms of T-kinin-induced increases in macromolecule extravasation in vivo.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:6

    Topics: Amino Acid Sequence; Animals; Bradykinin; Cricetinae; Dextrans; Edema; Fluorescein-5-isothiocyanate; Histamine Antagonists; Indomethacin; Macromolecular Substances; Male; Mesocricetus; Molecular Sequence Data; p-Methoxy-N-methylphenethylamine; Receptors, Bradykinin; Receptors, Neurokinin-1; Receptors, Neurotransmitter

1993
Characterization of receptor-mediated actions of T-kinin.
    Biochemical pharmacology, 1993, Nov-02, Volume: 46, Issue:9

    Topics: Amino Acid Sequence; Animals; Bradykinin; Dose-Response Relationship, Drug; Female; Indomethacin; Molecular Sequence Data; Muscle Contraction; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Structure-Activity Relationship; Tritium; Uterus

1993