t 593 has been researched along with histamine in 4 studies
*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]
*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]
| Studies (t 593) | Trials (t 593) | Recent Studies (post-2010) (t 593) | Studies (histamine) | Trials (histamine) | Recent Studies (post-2010) (histamine) |
|---|---|---|---|---|---|
| 14 | 0 | 1 | 37,718 | 1,372 | 3,457 |
| Protein | Taxonomy | t 593 (IC50) | histamine (IC50) |
|---|---|---|---|
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | 0.1585 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.1585 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arai, H; Hirai, S; Nakagawa, M; Tanada, K; Yamaguchi, H | 1 |
| Amagase, K; Kato, S; Okabe, S; Yamamoto, H | 1 |
| Arai, H; Inoie, M; Marubuchi, S | 1 |
| Arai, H; Inoie, M; Kimura, S; Kurokawa, K; Ono, K; Tashiro, T; Watanabe, T | 1 |
4 other study(ies) available for t 593 and histamine
| Article | Year |
|---|---|
Histamine H2-receptor antagonism of T-593: studies on positive chronotropic responses in guinea pig atria.
Topics: Animals; Binding Sites; Guanidines; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Male; Stimulation, Chemical; Sulfones | 1994 |
Effects of the novel histamine H2-receptor antagonist (+/-)-(E)-1-[2-hydroxy-2-(4-hydroxyphenyl)ethyl]-3-[2-[[[5- (methylamino)methyl-2-furyl]methyl]thio]ethyl]-2-(methylsulfonyl) guanidine on gastric secretion and gastroduodenal ulcers in rats.
Topics: Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Epirizole; Gastric Acid; Gastric Mucosa; Guanidines; Histamine; Histamine H2 Antagonists; Indomethacin; Male; Omeprazole; Pepsin A; Peptic Ulcer; Ranitidine; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Stress, Psychological; Sulfones | 1996 |
Histamine H2-receptor antagonism of T-593, an anti-ulcer agent: studies on aminopyrine accumulation in isolated canine gastric mucosal cells.
Topics: Aminopyrine; Animals; Anti-Ulcer Agents; Bucladesine; Carbachol; Carbon Radioisotopes; Cholinergic Agonists; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastric Mucosa; Guanidines; Histamine; Histamine H2 Antagonists; Omeprazole; Pentagastrin; Pirenzepine; Ranitidine; Sulfones | 1998 |
Histamine H2 receptor antagonism by T-593: studies on cAMP generation in Hepa cells expressing histamine H2 receptor.
Topics: Animals; Cyclic AMP; Dogs; Guanidines; Histamine; Histamine H2 Antagonists; Ranitidine; Rats; Stereoisomerism; Sulfones; Time Factors; Tumor Cells, Cultured | 1999 |