t 588 has been researched along with scopolamine hydrobromide in 2 studies
| Studies (t 588) | Trials (t 588) | Recent Studies (post-2010) (t 588) | Studies (scopolamine hydrobromide) | Trials (scopolamine hydrobromide) | Recent Studies (post-2010) (scopolamine hydrobromide) |
|---|---|---|---|---|---|
| 32 | 0 | 1 | 7,548 | 563 | 1,401 |
| Protein | Taxonomy | t 588 (IC50) | scopolamine hydrobromide (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.003 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 0.006 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.006 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.006 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.0006 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.006 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.006 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.0026 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ano, M; Hirata, K; Kitamura, K; Maekawa, M; Narita, H; Ono, S; Ukai, W; Yamafuji, T | 1 |
| Delgado-García, JM; Eleore, L; López-Ramos, JC; Yi, PJ | 1 |
2 other study(ies) available for t 588 and scopolamine hydrobromide
| Article | Year |
|---|---|
Protective effect of R(-)-1-(benzo[b]thiophen-5-yl)- 2-[2-(N,N-diethylamino)ethoxy]ethanol hydrochloride (T-588), a novel cerebral activator, against experimental cerebral anoxia.
Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Diethylamines; Energy Metabolism; Glycolysis; Hypoxia, Brain; Imipramine; Male; Mice; Mice, Inbred Strains; Pentobarbital; Potassium Cyanide; Scopolamine; Sleep; Tacrine; Thiophenes | 1993 |
The cognitive enhancer T-588 partially compensates the motor associative learning impairments induced by scopolamine injection in mice.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Association Learning; Avoidance Learning; Behavior, Animal; Conditioning, Eyelid; Diethylamines; Drug Interactions; Electromyography; Inhibition, Psychological; Learning Disabilities; Male; Mice; Motor Activity; Psychomotor Performance; Reaction Time; Recognition, Psychology; Scopolamine; Thiophenes; Time Factors | 2007 |