syringin and costunolide

syringin has been researched along with costunolide* in 3 studies

Other Studies

3 other study(ies) available for syringin and costunolide

ArticleYear
Hepatoprotective effect of syringin combined with costunolide against LPS-induced acute liver injury in L-02 cells via Rac1/AKT/NF-κB signaling pathway.
    Aging, 2023, 11-01, Volume: 15, Issue:21

    Topics: Lipopolysaccharides; Liver; NF-kappa B; Proto-Oncogene Proteins c-akt; Signal Transduction

2023
Syringin 4-O-beta-glucoside, a new phenylpropanoid glycoside, and costunolide, a nitric oxide synthase inhibitor, from the stem bark of Magnolia sieboldii.
    Journal of natural products, 1996, Volume: 59, Issue:12

    Syringin 4-O-beta-glucoside (1), a new phenylpropanoid glycoside, and costunolide (2) were isolated from the stem bark of Magnolia sieboldii. The structures were determined by spectroscopic and chemical methods. Costunolide (2) exhibited strong nitric oxide synthase inhibitory activity in the endotoxin-activated murine macrophage, J774.1.

    Topics: Animals; Cell Survival; Coloring Agents; Enzyme Inhibitors; Hydrolysis; Immunosuppressive Agents; Lactose; Macrophages; Magnetic Resonance Spectroscopy; Mice; Nitric Oxide; Nitric Oxide Synthase; Plant Epidermis; Plants, Medicinal; Sesquiterpenes; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles

1996
Sesquiterpene lactones and other constituents from a cytotoxic extract of Michelia floribunda.
    Pharmaceutical research, 1990, Volume: 7, Issue:12

    The pentane and CHCl3 fractions of a crude extract of Michelia floribunda exhibited cytotoxic activity when tested in KB and P388 tumor cell cultures. Repeated chromatography led to the isolation of three cytotoxic sesquiterpene lactones (costunolide, parthenolide, and santamarine) and a cytotoxic isoquinoline alkaloid (liriodenine). Inactive sesquiterpene lactones obtained during the course of this study included dihydroparthenolide and two new glucosides of dihydrotamaulipin A and dihydroreynosin (1 and 2). The structures of these new compounds were determined through interpretation of their spectroscopic data including 2D-NMR spectroscopy. Syringin was also isolated from the extract.

    Topics: Animals; Antineoplastic Agents, Phytogenic; Aporphines; Glucosides; Lactones; Phenylpropionates; Plant Extracts; Sesquiterpenes; Tumor Cells, Cultured

1990