Page last updated: 2024-08-18

synephrine and caffeine

synephrine has been researched along with caffeine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19904 (15.38)18.7374
1990's0 (0.00)18.2507
2000's6 (23.08)29.6817
2010's14 (53.85)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Rytter, M1
Kalsner, S1
Burgmann, W1
Grollman, AP; Marcus, DM1
OELSSNER, W1
Corbett, J; Delves, S; Harris, RC; Sale, C1
Benowitz, N; Duan, M; Haller, CA; Jacob, P1
Müller, GJ; Smedema, JP1
Blankenship, MM; Bloomer, RJ; Canale, RE; Fisher-Wellman, KH; Hammond, KG; Schilling, BK1
Burke, ER; Devonish, J; Nelson, A; Seifert, JG; Stohs, SJ1
Arbo, MD; Dallegrave, E; Krahn, CL; Leal, MB; Limberger, RP; Lorensi, AL; Maciel, ES; Mariotti, KC; Schmitt, GC1
Abdel-Rahman, A; Fabricant, D; George, NI; Hansen, DK; Pellicore, LS; White, GE2
Stohs, SJ1
Bush, JA; Diamond, KB; Faigenbaum, AD; Kang, J; Kraemer, WJ; Leise, MD; Nocera, VG; Ratamess, NA; Stohs, SJ1
Attipoe, S; Cohen, PA; Deuster, PA; Eichner, A1
Badmaev, V; Stohs, SJ1
Bush, JA; Ellis, NL; Faigenbaum, AD; Hasan, SB; Kang, J; Kuper, JD; O'Grady, EA; Ratamess, NA; Stohs, SJ; Vought, IT1
Shara, M; Smadi, MM; Stohs, SJ1
Bush, JA; Ellis, NL; Faigenbaum, AD; Kang, J; Kuper, JD; O'Grady, EA; Ratamess, NA; Stohs, SJ; Vought, IT1
Del Coso, J; Gutiérrez-Hellín, J1
Al-Khadhra, RS1
de Jonge, MLL; Egberink, LB; Kieviet, LC; Sierts, M; van der Heyden, MAG1

Reviews

2 review(s) available for synephrine and caffeine

ArticleYear
A Review of Natural Stimulant and Non-stimulant Thermogenic Agents.
    Phytotherapy research : PTR, 2016, Volume: 30, Issue:5

    Topics: Caffeine; Capsaicin; Central Nervous System Stimulants; Chlorogenic Acid; Ephedrine; Humans; Obesity; Overweight; Synephrine; Tea; Thermogenesis

2016
Review of Case Reports on Adverse Events Related to Pre-workout Supplements Containing Synephrine.
    Cardiovascular toxicology, 2023, Volume: 23, Issue:1

    Topics: Caffeine; Coronary Artery Disease; Dietary Supplements; Humans; Synephrine

2023

Trials

8 trial(s) available for synephrine and caffeine

ArticleYear
[Impotentia erectionis--therapeutic attempt using bamethan sulfate, synephrine, and coffeinum purum].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1973, Jun-15, Volume: 48, Issue:12

    Topics: Caffeine; Chlordiazepoxide; Clinical Trials as Topic; Drug Synergism; Erectile Dysfunction; Ethanolamines; Humans; Male; Neurotic Disorders; Pelvis; Placebos; Regional Blood Flow; Sympathectomy; Synephrine

1973
Metabolic and physiological effects of ingesting extracts of bitter orange, green tea and guarana at rest and during treadmill walking in overweight males.
    International journal of obesity (2005), 2006, Volume: 30, Issue:5

    Topics: Adenosine Triphosphate; Adult; Appetite Depressants; Blood Glucose; Blood Pressure; Breath Tests; Caffeine; Calorimetry, Indirect; Catechin; Citrus; Dietary Supplements; Double-Blind Method; Energy Metabolism; Fatty Acids, Nonesterified; Glycerol; Heart Rate; Humans; Lactic Acid; Male; Overweight; Oxygen Consumption; Paullinia; Plant Extracts; Synephrine; Tea; Walking

2006
Human pharmacology of a performance-enhancing dietary supplement under resting and exercise conditions.
    British journal of clinical pharmacology, 2008, Volume: 65, Issue:6

    Topics: Adult; Blood Glucose; Caffeine; Central Nervous System Stimulants; Dietary Supplements; Double-Blind Method; Energy Metabolism; Exercise; Female; Humans; Male; Statistics as Topic; Synephrine

2008
Effect of the dietary supplement Meltdown on catecholamine secretion, markers of lipolysis, and metabolic rate in men and women: a randomized, placebo controlled, cross-over study.
    Lipids in health and disease, 2009, Aug-05, Volume: 8

    Topics: Adipose Tissue; Analysis of Variance; Anti-Obesity Agents; Area Under Curve; Biomarkers; Caffeine; Catecholamines; Complex Mixtures; Cross-Over Studies; Dietary Supplements; Energy Intake; Energy Metabolism; Epinephrine; Fatty Acids, Nonesterified; Female; Glycerol; Humans; Lipolysis; Male; Norepinephrine; Obesity; Physical Fitness; Surveys and Questionnaires; Synephrine; Yohimbine; Young Adult

2009
Effect of acute administration of an herbal preparation on blood pressure and heart rate in humans.
    International journal of medical sciences, 2011, Mar-02, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Blood Pressure; Caffeine; Camellia sinensis; Citrus; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Heart Rate; Humans; Male; Paullinia; Placebos; Plant Extracts; Pulmonary Gas Exchange; Sex Characteristics; Synephrine; Young Adult

2011
The effects of supplementation with P-Synephrine alone and in combination with caffeine on resistance exercise performance.
    Journal of the International Society of Sports Nutrition, 2015, Volume: 12

    Topics: Athletic Performance; Caffeine; Dietary Supplements; Double-Blind Method; Humans; Isometric Contraction; Male; Muscle Strength; Muscle, Skeletal; Oxygen Consumption; Physical Endurance; Resistance Training; Synephrine; Young Adult

2015
Acute hematological and mood perception effects of bitter orange extract (p-synephrine) consumed alone and in combination with caffeine: A placebo-controlled, double-blind study.
    Phytotherapy research : PTR, 2018, Volume: 32, Issue:8

    Topics: Affect; Blood Chemical Analysis; Caffeine; Dietary Supplements; Double-Blind Method; Female; Hematocrit; Humans; Iron; Lipoproteins, VLDL; Male; Plant Extracts; Synephrine; Triglycerides; Young Adult

2018
Effects of p-Synephrine and Caffeine Ingestion on Substrate Oxidation during Exercise.
    Medicine and science in sports and exercise, 2018, Volume: 50, Issue:9

    Topics: Adipose Tissue; Adolescent; Adult; Caffeine; Dietary Supplements; Double-Blind Method; Energy Metabolism; Exercise; Female; Heart Rate; Humans; Male; Oxidation-Reduction; Oxygen Consumption; Synephrine; Young Adult

2018

Other Studies

16 other study(ies) available for synephrine and caffeine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Mechanism of potentiation of contractor responses to catecholamines by methylxanthines in aortic strips.
    British journal of pharmacology, 1971, Volume: 43, Issue:2

    Topics: Animals; Aorta; Caffeine; Catecholamines; Cycloparaffins; Drug Synergism; Epinephrine; In Vitro Techniques; Ketones; Methoxamine; Methylation; Muscle Contraction; Muscle, Smooth; Norepinephrine; Normetanephrine; Phenylephrine; Propiophenones; Pyrogallol; Rabbits; Reserpine; Synephrine; Theophylline; Xanthines

1971
[On the therapy of potency disorders in liver diseases].
    Die Medizinische Welt, 1968, Jul-06, Volume: 27

    Topics: Adult; Caffeine; Erectile Dysfunction; Humans; Liver Diseases; Male; Methyltestosterone; Middle Aged; Strychnine; Synephrine; Vitamin E; Yohimbine

1968
Ephedra-free is not danger-free.
    Science (New York, N.Y.), 2003, Sep-19, Volume: 301, Issue:5640

    Topics: Caffeine; Citrus; Dietary Supplements; Ephedra; Humans; Legislation, Drug; Legislation, Food; Plant Preparations; Synephrine; United States; United States Food and Drug Administration

2003
[Dye permeability in isolated, beating frog heart].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1951, Volume: 212, Issue:3-4

    Topics: Animals; Anura; Caffeine; Heart; Humans; Permeability; Ranidae; Sapogenins; Synephrine

1951
Coronary spasm and thrombosis in a bodybuilder using a nutritional supplement containing synephrine, octopamine, tyramine and caffeine.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2008, Volume: 98, Issue:5

    Topics: Adrenergic Uptake Inhibitors; Adult; Caffeine; Coronary Thrombosis; Coronary Vasospasm; Dietary Supplements; Humans; Male; Octopamine; Phosphodiesterase Inhibitors; Synephrine; Tyramine; Vasoconstrictor Agents; Weight Lifting

2008
Toxicological effects of a mixture used in weight loss products: p-synephrine associated with ephedrine, salicin, and caffeine.
    International journal of toxicology, 2012, Volume: 31, Issue:2

    Topics: Adrenergic Agents; Animals; Anti-Obesity Agents; Ataxia; Benzyl Alcohols; Body Temperature; Caffeine; Central Nervous System Stimulants; Drug Combinations; Ephedrine; Female; Glucosides; Male; Mice; Motor Activity; Synephrine

2012
Physiological effects following administration of Citrus aurantium for 28 days in rats.
    Toxicology and applied pharmacology, 2012, Jun-15, Volume: 261, Issue:3

    Topics: Animals; Blood Pressure; Body Temperature; Body Weight; Caffeine; Cardiovascular System; Central Nervous System Stimulants; Citrus; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Rate; Plant Extracts; Rats; Rats, Sprague-Dawley; Survival; Synephrine; Telemetry; Time Factors; Vasoconstrictor Agents

2012
Cardiovascular toxicity of Citrus aurantium in exercised rats.
    Cardiovascular toxicology, 2013, Volume: 13, Issue:3

    Topics: Analysis of Variance; Animals; Blood Pressure; Body Temperature; Body Weight; Caffeine; Cardiovascular Diseases; Central Nervous System Stimulants; Citrus; Dose-Response Relationship, Drug; Drug Synergism; Eating; Electrocardiography; Endpoint Determination; Female; Heart Rate; Long QT Syndrome; Physical Conditioning, Animal; Plant Extracts; Rats; Rats, Sprague-Dawley; Survival Analysis; Sympathomimetics; Synephrine

2013
Questionable conclusions in the article "Cardiovascular toxicity of Citrus aurantium in exercised rats".
    Cardiovascular toxicology, 2013, Volume: 13, Issue:2

    Topics: Animals; Blood Pressure; Caffeine; Cardiovascular Diseases; Citrus; Dose-Response Relationship, Drug; Drug Therapy, Combination; Heart; Heart Rate; Humans; Myocardium; Physical Conditioning, Animal; Plant Extracts; Rats; Species Specificity; Synephrine

2013
Variability of Stimulant Levels in Nine Sports Supplements Over a 9-Month Period.
    International journal of sport nutrition and exercise metabolism, 2016, Volume: 26, Issue:5

    Topics: Caffeine; Central Nervous System Stimulants; Dietary Supplements; Dose-Response Relationship, Drug; Ephedrine; Food Labeling; Humans; Octopamine; Phenylpropanolamine; Pilot Projects; Pseudoephedrine; Sports; Strychnine; Synephrine; Time Factors; United States

2016
Acute cardiovascular effects of bitter orange extract (p-synephrine) consumed alone and in combination with caffeine in human subjects: A placebo-controlled, double-blind study.
    Phytotherapy research : PTR, 2018, Volume: 32, Issue:1

    Topics: Acute Disease; Adult; Blood Pressure; Caffeine; Double-Blind Method; Female; Heart Rate; Humans; Male; Plant Extracts; Research Subjects; Synephrine; Young Adult

2018
Safety evaluation of p-synephrine following 15 days of oral administration to healthy subjects: A clinical study.
    Phytotherapy research : PTR, 2018, Volume: 32, Issue:1

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Adult; Caffeine; Citrus; Female; Healthy Volunteers; Humans; Male; Plant Extracts; Synephrine; Time Factors; Young Adult

2018
The determination of common anabolic steroid and stimulants in nutritional supplements by HPLC-DAD and LC-MS.
    Journal of chromatographic science, 2020, Apr-23, Volume: 58, Issue:4

    Topics: Amines; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Chromatography, Liquid; Clenbuterol; Dietary Supplements; Mass Spectrometry; Nandrolone; Reproducibility of Results; Synephrine; Testosterone Congeners

2020