Page last updated: 2024-09-05

symmetric dimethylarginine and omega-n-methylarginine

symmetric dimethylarginine has been researched along with omega-n-methylarginine in 20 studies

Compound Research Comparison

Studies
(symmetric dimethylarginine)
Trials
(symmetric dimethylarginine)
Recent Studies (post-2010)
(symmetric dimethylarginine)
Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010) (omega-n-methylarginine)
428273144,411344336

Protein Interaction Comparison

ProteinTaxonomysymmetric dimethylarginine (IC50)omega-n-methylarginine (IC50)
Neutrophil elastaseHomo sapiens (human)0.3
Proteinase-activated receptor 1Homo sapiens (human)0.0018
Nitric oxide synthase, endothelialBos taurus (cattle)7
Nitric oxide synthase, endothelialHomo sapiens (human)2.9489
Nitric oxide synthase, brainHomo sapiens (human)3.3983
Nitric oxide synthase, brain Rattus norvegicus (Norway rat)7.5
Nitric oxide synthase, inducibleMus musculus (house mouse)2.3
Nitric oxide synthase, inducibleHomo sapiens (human)2.9252
Collagenase 3Homo sapiens (human)0.3
Nitric oxide synthase, brainMus musculus (house mouse)4.3

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.00)18.2507
2000's7 (35.00)29.6817
2010's9 (45.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Dillon, MJ; Frend, A; Goonasekera, CD; Rees, DD; Shah, V; Woolard, P1
Aso, T; Azuma, H; Beppu, M; Goto, M; Obayashi, S1
Azuma, H; Goto, M; Kihara, K; Masuda, H; Sakai, Y; Yano, M1
Dweik, RA1
Barbara, JA; Hewitson, CL; Mangoni, AA; McAteer-Carr, B; Whiting, MJ; Woodman, RJ1
Carru, C; Deiana, L; Scanu, B; Sotgia, S; Zinellu, A1
Blackwelder, WC; Hazen, SL; Kato, GJ; Machado, RF; Taylor, JG; Wang, Z1
Brennan, DM; Cho, L; Hazen, SL; Tang, WH; Wang, Z1
Caplin, B; Leiper, J1
Linz, TH; Lunte, SM1
Appelbaum, S; Atzler, D; Bauer, C; Blankenberg, S; Böger, RH; Hoffmann, B; Lackner, KJ; Münzel, T; Ojeda, FM; Ramuschkat, M; Schnabel, RB; Schwedhelm, E; Sinning, CR; Wild, PS; Zeller, T1
Cherkanova, MS; Gilinsky, MA; Sukhovershin, RA1
Bazer, FW; Che, D; Hou, Y; Hu, S; Jia, S; Nawaratna, G; Wang, F; Wu, G1
Bailey, FJ; Lundgren, BR; Moley, G; Nomura, CT1
Arós, F; Clish, CB; Corella, D; Estruch, R; Fitó, M; Gómez-Gracia, E; Guasch-Ferré, M; Hruby, A; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Toledo, E; Wang, DD; Yu, E1
Bode-Böger, SM; Emrich, IE; Fliser, D; Heine, GH; Martens-Lobenhoffer, J; Wagenpfeil, S; Zawada, AM1
Arós, F; Bullo, M; Clish, C; Cofán, M; Corella, D; Dennis, C; Estruch, R; Fitó, M; Guasch-Ferré, M; Gutiérrez-Bedmar, M; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Papandreou, C; Razquin, C; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Sorlí, JV; Toledo, E; Wang, DD; Yu, E1
Abusoglu, G; Abusoglu, S; Avci, A; Demir, K; Eryavuz, D; Hosaf, M; Unlu, A1
Alptekin, H; Karaman, S; Onmaz, DE; Sivrikaya, A1
Doğan, Ö; Haşimi, A; Serdar, CC; Serdar, MA1

Reviews

2 review(s) available for symmetric dimethylarginine and omega-n-methylarginine

ArticleYear
The lung in the balance: arginine, methylated arginines, and nitric oxide.
    American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 292, Issue:1

    Topics: Animals; Arginine; Humans; Lung; Methylation; Models, Biological; Nitric Oxide; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases

2007
Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators, and regulators?
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:6

    Topics: Amidohydrolases; Animals; Arginine; Binding Sites; Binding, Competitive; Biomarkers; Cardiovascular Agents; Cardiovascular Diseases; Catalytic Domain; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine

2012

Other Studies

18 other study(ies) available for symmetric dimethylarginine and omega-n-methylarginine

ArticleYear
Nitric oxide synthase inhibitors and hypertension in children and adolescents.
    Journal of hypertension, 1997, Volume: 15, Issue:8

    Topics: Adolescent; Animals; Arginine; Child; Endothelium, Vascular; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; In Vitro Techniques; Male; Mice; Muscle Contraction; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Renin; Vasoconstrictor Agents

1997
Endogenous nitric oxide synthase inhibitors in endothelial cells, endothelin-1 within the vessel wall, and intimal hyperplasia in perimenopausal human uterine arteries.
    Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:2

    Topics: Adult; Arginine; Arteries; Chromatography, High Pressure Liquid; Climacteric; Cyclic GMP; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hyperplasia; In Vitro Techniques; Middle Aged; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Tunica Intima; Tunica Media; Uterus

2002
Roles of accumulated endogenous nitric oxide synthase inhibitors and decreased nitric oxide synthase activity for impaired trigonal relaxation with ischemia.
    The Journal of urology, 2003, Volume: 170, Issue:4 Pt 1

    Topics: Animals; Arginine; Electric Stimulation; Ischemia; Male; Muscle Relaxation; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rabbits; Urinary Bladder

2003
Symmetric dimethylarginine is an independent predictor of intradialytic hypotension.
    American journal of hypertension, 2008, Volume: 21, Issue:8

    Topics: Aged; Arginine; Biomarkers; Blood Pressure; Female; Humans; Hypotension; Kidney Failure, Chronic; Male; Middle Aged; omega-N-Methylarginine; Predictive Value of Tests; Renal Dialysis

2008
Determination of protein-incorporated methylated arginine reference values in healthy subjects whole blood and evaluation of factors affecting protein methylation.
    Clinical biochemistry, 2008, Volume: 41, Issue:14-15

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Female; Health; Humans; Male; Methylation; Middle Aged; omega-N-Methylarginine; Proteins; Reference Values; Regression Analysis

2008
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death.
    British journal of haematology, 2009, Volume: 145, Issue:4

    Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Citrulline; Follow-Up Studies; Hemolysis; Humans; Hypertension, Pulmonary; Kidney Diseases; Linear Models; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Proportional Hazards Models; Risk; Survival Rate

2009
Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:9

    Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Citrulline; Coronary Artery Disease; Creatinine; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Nitric Oxide Synthase; Odds Ratio; omega-N-Methylarginine; Ornithine; Prognosis; Prospective Studies; Protein Processing, Post-Translational; Risk Assessment; Risk Factors; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors

2009
Heat-assisted extraction for the determination of methylarginines in serum by CE.
    Electrophoresis, 2013, Volume: 34, Issue:11

    Topics: Arginine; Cardiovascular Diseases; Electrophoresis, Capillary; Hot Temperature; Humans; omega-N-Methylarginine; Solid Phase Extraction

2013
ADMA, subclinical changes and atrial fibrillation in the general population.
    International journal of cardiology, 2016, Jan-15, Volume: 203

    Topics: Adult; Aged; Arginine; Atrial Fibrillation; Biomarkers; Chromatography, Liquid; Echocardiography; Electrocardiography; Female; Germany; Humans; Male; Middle Aged; Morbidity; omega-N-Methylarginine; Oxidative Stress; Population Surveillance; Tandem Mass Spectrometry

2016
Methylarginines in Mice with Experimental Atherosclerosis.
    Bulletin of experimental biology and medicine, 2015, Volume: 160, Issue:1

    Topics: Animals; Arginine; Atherosclerosis; Cholesterol; Endothelium, Vascular; Male; Mice; Mice, Inbred CBA; Nitric Oxide Synthase; omega-N-Methylarginine; Poloxamer; Triglycerides

2015
Whole-body synthesis of L-homoarginine in pigs and rats supplemented with L-arginine.
    Amino acids, 2016, Volume: 48, Issue:4

    Topics: Animal Feed; Animals; Arginine; Body Weight; Creatinine; Dietary Supplements; Female; Glycine max; Homoarginine; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Swine; Zea mays

2016
DdaR (PA1196) Regulates Expression of Dimethylarginine Dimethylaminohydrolase for the Metabolism of Methylarginines in Pseudomonas aeruginosa PAO1.
    Journal of bacteriology, 2017, 04-15, Volume: 199, Issue:8

    Topics: Amidohydrolases; Arginine; Bacterial Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; omega-N-Methylarginine; Pseudomonas aeruginosa; RNA Polymerase Sigma 54

2017
Plasma Arginine/Asymmetric Dimethylarginine Ratio and Incidence of Cardiovascular Events: A Case-Cohort Study.
    The Journal of clinical endocrinology and metabolism, 2017, 06-01, Volume: 102, Issue:6

    Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chromatography, Liquid; Citrulline; Cohort Studies; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; omega-N-Methylarginine; Ornithine; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Tandem Mass Spectrometry

2017
Symmetric dimethylarginine (SDMA) outperforms asymmetric dimethylarginine (ADMA) and other methylarginines as predictor of renal and cardiovascular outcome in non-dialysis chronic kidney disease.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2018, Volume: 107, Issue:3

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Chromatography, Liquid; Disease Progression; Female; Germany; Humans; Incidence; Male; Middle Aged; omega-N-Methylarginine; Prognosis; Renal Dialysis; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors

2018
Changes in arginine are inversely associated with type 2 diabetes: A case-cohort study in the PREDIMED trial.
    Diabetes, obesity & metabolism, 2019, Volume: 21, Issue:2

    Topics: Aged; Aged, 80 and over; Arginine; Case-Control Studies; Citrulline; Cohort Studies; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Diet, Mediterranean; Female; Humans; Incidence; Insulin Resistance; Male; Middle Aged; omega-N-Methylarginine; Ornithine; Risk Factors

2019
Total methylated arginine load as a risk parameter in subjects with masked hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2020, Volume: 42, Issue:2

    Topics: Arginine; Biomarkers; Blood Pressure Determination; Female; Humans; Hypertension; Male; Masked Hypertension; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Risk Factors

2020
Altered methylarginine levels after surgery in subjects with multinodular goiter.
    Hormone molecular biology and clinical investigation, 2021, Feb-22, Volume: 42, Issue:3

    Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Goiter, Nodular; Humans; Male; Middle Aged; omega-N-Methylarginine; Postoperative Period; Sensitivity and Specificity

2021
Association of serum ADMA, SDMA and L-NMMA concentrations with disease progression in COVID-19 patients.
    Biochemia medica, 2023, Feb-15, Volume: 33, Issue:1

    Topics: Arginine; COVID-19; Disease Progression; Humans; omega-N-Methylarginine

2023