suramin has been researched along with uridine triphosphate in 133 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 56 (42.11) | 18.2507 |
| 2000's | 68 (51.13) | 29.6817 |
| 2010's | 9 (6.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobson, KA; Jarvis, MF; Williams, M | 1 |
| Fischer, R; Nauck, M; Pavenstädt, H; Schlunck, G; Schollmeyer, P; Späth, M; Wanner, C | 1 |
| Boarder, MR; Murrin, RJ | 1 |
| Bültmann, R; Starke, K; von Kügelgen, I | 1 |
| Aliev, G; Caparrotta, L; Chinellato, A; Fassina, G; Froldi, G; Pandolfo, L; Prosdocimi, M; Ragazzi, E | 1 |
| Humphrey, PP; Kennedy, I | 1 |
| Evans, RJ; Kennedy, C | 1 |
| Hourani, SM; Johnson, CR | 1 |
| Barbosa, RM; Castro, E; Mateo, J; Miras-Portugal, MT; Rosário, LM; Tomé, AR | 1 |
| Enomoto, K; Furuya, K; Maeno, T; Oka, T; Yamagishi, S | 1 |
| Chen, ZP; Levy, A; Lightman, SL; McArdle, CA | 1 |
| Caparrotta, L; Chinellato, A; Fassina, G; Froldi, G; Pandolfo, L; Ragazzi, E | 1 |
| Boarder, MR; Dainty, IA; McKechnie, K; Wilkinson, GF | 1 |
| den Hertog, A; Duin, M; Henning, RH; Nelemans, A | 1 |
| Boarder, MR; Purkiss, JR; Wilkinson, GF | 1 |
| Inoue, K; Koizumi, S; Nakazawa, K | 1 |
| Connolly, GP; Harrison, PJ | 1 |
| Hicks, J; Ho, C; Salter, MW | 1 |
| Barnard, EA; Burnstock, G; King, BF; Simon, J; Webb, TE | 1 |
| Bradley, ME; Buxton, IL; Probert, CB; Talbot, JN; Yang, S | 1 |
| Hollingsworth, M; Piper, AS | 1 |
| Burnstock, G; Ralevic, V | 1 |
| Boarder, MR; Brown, CA; Charlton, SJ; Erb, L; Turner, JT; Weisman, GA | 2 |
| Kennedy, C; Rae, MG; Robertson, SJ; Rowan, EG | 1 |
| Burnstock, G; Rubino, A | 1 |
| Charlton, SJ; Hourani, SM; Johnson, CR | 1 |
| Burnstock, G; Knight, GE | 1 |
| Kokubun, S; Sawai, H; Wang, R; Yamashita, T | 1 |
| Dixon, SJ; Hill, DJ; Kaplan, AD; Kilkenny, DM | 1 |
| Czubayko, U; Reiser, G | 1 |
| Boehm, S; Fröhlich, R; Illes, P | 1 |
| Ito, S; Nakazato, Y; Ohta, T; Otsuguro, K | 1 |
| Conigrave, AD; Killen, JP; Macdonald, PS; Owe-Young, R; Qasabian, RA; Schyvens, C; Williamson, DJ | 1 |
| Meggyesy, C; Miller, SS; Peterson, WM; Yu, K | 1 |
| Iizuka, Y; Ishizaki, M; Kimura, T; Satoh, S; Suzuki-Kusaba, M | 1 |
| Fukuda, S; Higashiyama, M; Ishikawa, S; Kusaka, I; Nagasaka, S; Saito, T | 1 |
| Furukawa, M; Ikeda, K; Suzuki, H; Takasaka, T | 1 |
| Chiba, S; Matsumoto, T; Nakane, T | 1 |
| Korngreen, A; Ma, W; Priel, Z; Silberberg, SD | 1 |
| Dunne, MJ; James, RF; London, NJ; Squires, PE | 1 |
| Kennedy, C; McLaren, GJ; Sneddon, P | 1 |
| Boehm, S | 1 |
| Buda, MD; Hughes, RJ; Insel, PA; Jacobson, JP; Kao, CC; Post, SR; Rump, LC; Zambon, A | 1 |
| Bilbe, G; Crespo, J; Fakler, B; Glatz, A; Maier, R; Mosbacher, J | 1 |
| Hartley, SA; Kato, K; Kozlowski, RZ; Salter, KJ | 1 |
| Hoffmann, EK; Lambert, IH; Pedersen, S; Pedersen, SF | 1 |
| Bailey, SJ; Hourani, SM; Johnson, CR; Tennant, JP | 1 |
| Cha, SH; Endou, H; Sekine, T | 1 |
| Konishi, C; Naito, Y; Ohara, N | 1 |
| Evans, RJ; Grubb, BD | 1 |
| Fleckenstein-Grün, G; Matyas, S; Seiler, L | 1 |
| Burnstock, G; Rubino, A; Ziabary, L | 1 |
| Hourani, SM; Park, HS | 1 |
| Hosoya, K; Kim, KJ; Lee, VH; Ueda, H | 1 |
| Nishi, H | 1 |
| Scemes, E; Spray, DC; Suadicani, SO | 1 |
| Dixon, CJ; Green, AK; Webb, TE; Woods, NM | 1 |
| Huwiler, A; Pfeilschifter, J; van den Bosch, H; Wartmann, M | 1 |
| Avliyakulov, NK; Kajava, AV; Liedberg, B; Lukes, J; Lundström, I; Svensson, SP | 1 |
| Hirai, K; Sugamoto, Y; Tokoro, T | 1 |
| Bidet, M; Cuiller, B; De Renzis, G; Poujeol, C; Poujeol, P; Rubera, I; Tauc, M; Verheecke-Mauze, C | 1 |
| Carolan, BM; Harden, TK; Keef, KD; Mutafova-Yambolieva, VN | 1 |
| Boeynaems, JM; Castro, E; Communi, D; Delicado, EG; Jiménez, AI; Miras-Portugal, MT | 1 |
| Boarder, MR; Kumari, R; London, NJ; Ng, LL; Porter, KE; White, PJ | 1 |
| Evans, RJ; Gitterman, DP | 1 |
| Kaszkin, M; Pfeilschifter, J; Scholz-Pedretti, K | 1 |
| Dacey, RG; Dietrich, HH; Horiuchi, T; Tsugane, S | 1 |
| Aitken, H; Hollingsworth, M; Poyser, NL | 1 |
| Saino, T; Shinohe, Y | 1 |
| Bernard, C; Butlen, D; Ferrary, E; Teixeira, M | 1 |
| Kato, M; Nakajima, Y; Sakuma, Y; Uchiyama, M | 1 |
| Kelve, M; Sak, K; Samuel, K; Webb, TE | 1 |
| Boeynaems, J; Pouillon, V; Robaye, B; Suarez-Huerta, N | 1 |
| Marcus, DC; Scofield, MA | 1 |
| Hsieh, HL; Lin, CM; Liu, PS | 1 |
| Banes, AJ; Elfervig, MK; Graff, RD; Kelley, SS; Lee, GM; Sood, A | 1 |
| Chiba, T; Lee, JH; Marcus, DC | 1 |
| Gorodeski, GI | 1 |
| Belloc, I; Chaulet, H; Desgranges, C; Dupuch, F; Gadeau, AP; Pillois, X | 1 |
| Imamura, H; Kido, M; Lu, K; Ninomiya, H; Otani, H; Uchiyama, T | 1 |
| Bell, PD; Johansson, A; Kovacs, G; Liu, R; Persson, AE; Peti-Peterdi, J | 1 |
| Habara, Y; Takahashi-Iwanaga, H | 2 |
| Dorsch, S; Huwiler, A; Pfeilschifter, J; Ren, S; Rölz, W | 1 |
| Katayama, T; Kawaguchi, N; Minami, M; Nakagawa, T; Nakamura, J; Ohtani, Y; Satoh, M; Yamakuni, H | 1 |
| Leite, M; Rohatgi, R; Satlin, LM; Woda, CB | 1 |
| Becker, D; Catsicas, M; Mobbs, P; Pearson, R | 1 |
| Chambers, JK; Emson, PC; Moore, DJ; Murdock, PR | 1 |
| Blaug, S; Jalickee, S; Miller, SS; Rymer, J | 1 |
| Gallagher, CJ; Salter, MW | 1 |
| Fujihara, T; Murakami, T; Nakamura, M; Nakata, K | 1 |
| King, BF; Unwin, RJ; Wildman, SS | 1 |
| Boarder, MR; Goh, G; Kumari, R; Ng, LL | 1 |
| Böing, B; Braun, K; Ganso, M; Kassack, MU; Lambrecht, G; Müller, G; Nickel, P; Ullmann, H | 1 |
| Choi, SJ; Kim, JH; Kim, MH; Kim, SJ; Koh, DS; Lee, JE; Min, KM; Nam, JH; Uhm, DY | 1 |
| Jackson, AD; Kemp, PA; Sugar, RA | 1 |
| Delbro, DS; Nordgren, S; Nylund, G | 1 |
| Gu, X; Sagawa, M; Sakuda, M; Sakuma, T; Sugita, M; Toga, H | 1 |
| Atterbury-Thomas, AE; Calvert, JA; Evans, RJ; Forsythe, ID; Gachet, C; Leon, C | 1 |
| Bennett, MR; Lin, YQ | 2 |
| Bennett, MR; Liu, GJ; Werry, EL | 1 |
| Jacobson, KA; Shainberg, A; Shneyvays, V; Yitzhaki, S | 1 |
| Afzalov, R; Giniatullin, A; Giniatullin, R; Grishin, S; Shakirzyanova, A | 1 |
| Burnstock, G; Cowen, T; Knight, GE; Wallace, A | 1 |
| Beierwaltes, WH; Garvin, JL; Silva, G | 1 |
| Kobayashi, D; Nakahata, N; Ohkubo, S; Yoshida, H | 1 |
| Chang, SO; Heo, JH; Kim, CS; Lee, JH; Oh, SH | 1 |
| Neary, JT; Washburn, KB | 1 |
| Arnold, A; Brandt, A; Milosevic, J; Roemuss, U; Schwarz, J; Schwarz, SC; Storch, A; Wegner, F; Zimmermann, H | 1 |
| Alexander, SP; Latif, ML; Ralevic, V; Rayment, SJ | 1 |
| Housley, GD; Soeller, C; Thorne, PR; Vlajkovic, SM; Wang, CJ; Zimmermann, H | 1 |
| Hughes, I; Ornitz, DM; Saito, M; Schlesinger, PH | 1 |
| Ishibashi, K; Okamura, K; Yamazaki, J | 1 |
| Yu, N; Zhao, HB | 1 |
| Baek, EB; Earm, YE; Kim, HS; Kim, SD; Kim, SJ; Park, SJ; Yoo, HY | 1 |
| Burnstock, G; Fan, J; Ma, B; Ni, X; Yu, LH | 1 |
| Chow, JY; Dong, H; Dong, X; Insel, PA; Kim, HD; Ko, KH; Lee, J; Smoll, EJ | 1 |
| Hegg, CC; Jia, C; Kanekar, S | 1 |
| Bachmatov, L; Ben-Ari, Z; Cheporko, Y; Hochhauser, E; Kurtzwald, E; Mor, E; Pappo, O; Ravid, A; Shainberg, A; Yitzhaki, S; Zemel, R; Zinman, T | 1 |
| Crudgington, S; Doherty, JP; Hegg, CC; Jia, C | 1 |
| Gendron, FP; Langlois, C | 1 |
| Sato, A; Shitara, A; Tanimura, A; Tojyo, Y | 1 |
| Chen, X; Gebhart, GF; Molliver, DC | 1 |
| Galligan, JJ; Wang, DH; Wang, H | 1 |
| Camp, R; Ding, L; Littmann, T; Ma, W; Shen, J | 1 |
| Burnstock, G; Crawford, C; Elliott, J; Fordham, AF; Janska, SE; Knight, GE; Peppiatt-Wildman, CM; Wildman, SS; Zerpa, H | 1 |
| Burnstock, G; Deng, XM; Li, N; Lu, ZY; Ma, B; Yu, LH | 1 |
| Li, D; Liu, MD; Wang, YB; Xu, LJ; Yuan, WS | 1 |
| Correa, G; Coutinho, CM; Coutinho-Silva, R; Marinho, Y; Moreira-Souza, AC; Santoro, GF; Vommaro, RC | 1 |
| Gan, X; Hu, WP; Qiu, CY; Ren, C; Wu, J | 1 |
| Balachandran, AA; Contreras-Sanz, A; Curtiss, NL; Duckett, J; Gill, HS; Kelley, S; Khasriya, R; Krska, L; Malone-Lee, J; Mansfield, KJ; Peppiatt-Wildman, CM; Strutt, M; Taylor, KM; Wildman, SS; Wu, C | 1 |
1 review(s) available for suramin and uridine triphosphate
| Article | Year |
|---|---|
Purine and pyrimidine (P2) receptors as drug targets.
Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate | 2002 |
132 other study(ies) available for suramin and uridine triphosphate
| Article | Year |
|---|---|
Effect of nucleotides on the cytosolic free calcium activity and inositol phosphate formation in human glomerular epithelial cells.
Topics: Adenosine Triphosphate; Calcium; Cells, Cultured; Cytosol; Down-Regulation; Epithelium; Fura-2; Inosine Triphosphate; Inositol Phosphates; Kidney Glomerulus; Nucleotides; Protein Kinase C; Spectrometry, Fluorescence; Suramin; Tetradecanoylphorbol Acetate; Uridine Diphosphate; Uridine Triphosphate | 1992 |
Neuronal "nucleotide" receptor linked to phospholipase C and phospholipase D? Stimulation of PC12 cells by ATP analogues and UTP.
Topics: Adenosine Triphosphate; Animals; Glycerophospholipids; Inositol Phosphates; Neurons; PC12 Cells; Phosphatidic Acids; Phospholipase D; Receptors, Purinergic; Suramin; Type C Phospholipases; Uridine Triphosphate | 1992 |
Interaction of adenine nucleotides, UTP and suramin in mouse vas deferens: suramin-sensitive and suramin-insensitive components in the contractile effect of ATP.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Norepinephrine; Suramin; Uridine Triphosphate; Vas Deferens | 1990 |
Endothelial nucleotide-mediated aorta relaxation in aged Watanabe heritable hyperlipidemic rabbits.
Topics: Acetylcholine; Adenosine Triphosphate; Aging; Animals; Aorta, Thoracic; Arginine; Arteriosclerosis; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Hyperlipidemia, Familial Combined; Male; Methylene Blue; Microscopy, Electron; Microscopy, Electron, Scanning; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Purinergic Antagonists; Rabbits; Receptors, Muscarinic; Receptors, Purinergic; Suramin; Uridine Triphosphate | 1995 |
Evidence for the presence of two types of P2 purinoceptor in the guinea-pig ileal longitudinal smooth muscle preparation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Atropine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Receptors, Purinergic P2; Suramin; Tetrodotoxin; Triazines; Uridine Triphosphate | 1994 |
Characterization of P2-purinoceptors in the smooth muscle of the rat tail artery: a comparison between contractile and electrophysiological responses.
Topics: Adenosine Triphosphate; Animals; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Tail; Thionucleotides; Uridine Triphosphate; Vasoconstriction | 1994 |
Contractile effects of uridine 5'-triphosphate in the rat duodenum.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Duodenum; Guanosine Triphosphate; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Suramin; Uridine Triphosphate | 1994 |
Cell-specific purinergic receptors coupled to Ca2+ entry and Ca2+ release from internal stores in adrenal chromaffin cells. Differential sensitivity to UTP and suramin.
Topics: Adenosine Triphosphate; Adrenal Medulla; Animals; Calcium; Cattle; Cells, Cultured; Dimethylphenylpiperazinium Iodide; Epinephrine; Fura-2; Kinetics; Manganese; Norepinephrine; Receptors, Purinergic; Sensitivity and Specificity; Spectrometry, Fluorescence; Suramin; Time Factors; Uridine Triphosphate | 1995 |
The increase in the intracellular Ca2+ concentration induced by mechanical stimulation is propagated via release of pyrophosphorylated nucleotides in mammary epithelial cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Epithelial Cells; Epithelium; Female; Fura-2; Mammary Neoplasms, Experimental; Mice; Nucleotides; Phosphorylation; Physical Stimulation; Suramin; Tumor Cells, Cultured; Uridine Diphosphate; Uridine Triphosphate | 1994 |
Pituitary ATP receptors: characterization and functional localization to gonadotropes.
Topics: Animals; Calcium; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Female; Gonadotropins; Osmolar Concentration; Pituitary Gland; Pituitary Gland, Anterior; Rats; Receptors, Purinergic P2; Suramin; Tissue Distribution; Uridine Triphosphate | 1994 |
Purine- and nucleotide-mediated relaxation of rabbit thoracic aorta: common and different sites of action.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Inosine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nucleotides; Purines; Rabbits; Suramin; Uridine Triphosphate; Vasodilator Agents | 1994 |
P2Y purinoceptor and nucleotide receptor-induced relaxation of precontracted bovine aortic collateral artery rings: differential sensitivity to suramin and indomethacin.
Topics: Adenosine Triphosphate; Animals; Aorta; Cattle; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Nitric Oxide; Receptors, Purinergic P2; Suramin; Uridine Triphosphate; Vasodilation | 1994 |
Activation of the phospholipase C pathway by ATP is mediated exclusively through nucleotide type P2-purinoceptors in C2C12 myotubes.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Line; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mice; Muscles; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Suramin; Type C Phospholipases; Uridine Triphosphate | 1993 |
The regulation of aortic endothelial cells by purines and pyrimidines involves co-existing P2y-purinoceptors and nucleotide receptors linked to phospholipase C.
Topics: Adenosine Triphosphate; Animals; Cattle; Cells, Cultured; Endothelium, Vascular; In Vitro Techniques; Inositol Phosphates; Purine Nucleotides; Purines; Pyrimidines; Receptors, Purinergic; Suramin; Type C Phospholipases; Uridine Triphosphate | 1993 |
Inhibition by Zn2+ of uridine 5'-triphosphate-induced Ca(2+)-influx but not Ca(2+)-mobilization in rat phaeochromocytoma cells.
Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Animals; Calcium; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Fura-2; Nicardipine; PC12 Cells; Pheochromocytoma; Rats; Receptors, Purinergic; Suramin; Thionucleotides; Uridine Triphosphate; Zinc | 1995 |
Structure-activity relationship of a pyrimidine receptor in the rat isolated superior cervical ganglion.
Topics: Aminoglycosides; Aminoimidazole Carboxamide; Animals; Anti-Bacterial Agents; Male; Membrane Potentials; Pyrimidine Nucleosides; Pyrimidine Nucleotides; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Ribonucleotides; Structure-Activity Relationship; Superior Cervical Ganglion; Suramin; Uridine; Uridine Triphosphate | 1995 |
A novel P2-purinoceptor expressed by a subpopulation of astrocytes from the dorsal spinal cord of the rat.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium; Carbachol; Cells, Cultured; Drug Interactions; Pertussis Toxin; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Spinal Cord; Suramin; Thionucleotides; Uridine Triphosphate; Virulence Factors, Bordetella | 1995 |
Characterisation of a recombinant P2Y purinoceptor.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Brain; Cell Line; Electrophysiology; Inositol Phosphates; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Recombinant Proteins; Suramin; Thionucleotides; Triazines; Uridine Triphosphate; Xenopus | 1995 |
Evidence for a discrete UTP receptor in cardiac endothelial cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Female; Guinea Pigs; Pertussis Toxin; Purinergic P2 Receptor Agonists; Receptors, Cell Surface; Receptors, Purinergic P2; Suramin; Uridine Triphosphate; Virulence Factors, Bordetella | 1996 |
P2-purinoceptors mediating spasm of the isolated uterus of the non-pregnant guinea-pig.
Topics: Adenosine Triphosphate; Animals; Female; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smooth; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P1; Receptors, Purinergic P2; Spasm; Suramin; Theophylline; Thioinosine; Thionucleotides; Uridine Triphosphate; Uterus | 1996 |
Relative contribution of P2U- and P2Y-purinoceptors to endothelium-dependent vasodilatation in the golden hamster isolated mesenteric arterial bed.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cricetinae; Endothelium, Vascular; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Rats; Receptors, Purinergic P2; Suramin; Uridine Triphosphate; Vasoconstrictor Agents; Vasodilation | 1996 |
PPADS and suramin as antagonists at cloned P2Y- and P2U-purinoceptors.
Topics: Cell Line; Dose-Response Relationship, Drug; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Suramin; Transfection; Uridine Triphosphate | 1996 |
Characterization of a P2X-purinoceptor in cultured neurones of the rat dorsal root ganglia.
Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electrophysiology; Ganglia, Spinal; Membrane Potentials; Patch-Clamp Techniques; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Suramin; Uridine Triphosphate | 1996 |
Evidence for a P2-purinoceptor mediating vasoconstriction by UTP, ATP and related nucleotides in the isolated pulmonary vascular bed of the rat.
Topics: Adenosine Triphosphate; Animals; In Vitro Techniques; Male; Platelet Aggregation Inhibitors; Pulmonary Circulation; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Uridine Triphosphate; Vasoconstriction | 1996 |
Responses of the longitudinal muscle and the muscularis mucosae of the rat duodenum to adenine and uracil nucleotides.
Topics: Adenosine Triphosphate; Animals; Duodenum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Rats; Rats, Wistar; Suramin; Uridine Triphosphate | 1996 |
The effects of purine compounds on the isolated aorta of the frog Rana temporaria.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Pyridoxal Phosphate; Rana temporaria; Receptors, Purinergic; Suramin; Uridine Triphosphate; Vasoconstriction; Vasodilation | 1996 |
Effects of purinoceptor agonists on cytosolic Ca2+ concentration in swine tracheal smooth muscle cells in culture.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Inositol 1,4,5-Trisphosphate; Muscle, Smooth; Receptors, Purinergic; Suramin; Swine; Trachea; Uridine Triphosphate | 1996 |
Extracellular nucleotides act through P2U purinoceptors to elevate [Ca2+]i and enhance basic fibroblast growth factor-induced proliferation in sheep chondrocytes.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Bradykinin; Calcium; Cartilage, Articular; Cell Division; Cells, Cultured; DNA; Drug Synergism; Fetus; Fibroblast Growth Factor 2; Fluorescent Dyes; Growth Plate; Kinetics; Lysophospholipids; Pertussis Toxin; Receptors, Purinergic P2; Sheep; Signal Transduction; Suramin; Thapsigargin; Uridine Triphosphate; Virulence Factors, Bordetella | 1996 |
Desensitization of P2U receptor in neuronal cell line. Different control by the agonists ATP and UTP, as demonstrated by single-cell Ca2+ responses.
Topics: Adenosine Triphosphate; Bradykinin; Calcium; Cell Line; Neurons; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Tumor Cells, Cultured; Uridine Triphosphate | 1996 |
Cloned and transfected P2Y4 receptors: characterization of a suramin and PPADS-insensitive response to UTP.
Topics: Cell Line; Cloning, Molecular; Humans; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Transfection; Uridine Triphosphate | 1996 |
Pharmacological characterization of P2 purinoceptor types in rat locus coeruleus neurons.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Locus Coeruleus; Male; Membrane Potentials; Rats; Rats, Wistar; Receptors, Purinergic; Suramin; Uridine Triphosphate | 1996 |
Influence of purines and pyrimidines on circular muscle of the rat proximal stomach.
Topics: Adenosine Triphosphate; Animals; Calcium; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Purinergic Agonists; Purinergic Antagonists; Purines; Pyrimidines; Rats; Rats, Wistar; Stomach; Suramin; Uridine Triphosphate | 1996 |
Characterization of the P2 receptors in rabbit pulmonary artery.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Pulmonary Artery; Rabbits; Receptors, Purinergic P1; Suramin; Uridine Triphosphate; Vasodilation | 1997 |
Extracellular ATP activates calcium signaling, ion, and fluid transport in retinal pigment epithelium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Adenosine Triphosphate; Animals; Barium; Calcium; Calcium-Transporting ATPases; Cattle; Cell Membrane; Cells, Cultured; Chelating Agents; Egtazic Acid; Electrophysiology; Enzyme Inhibitors; Indoles; Kinetics; Membrane Potentials; Models, Biological; Pigment Epithelium of Eye; Purinergic Antagonists; Receptors, Purinergic; Signal Transduction; Suramin; Time Factors; Uridine Triphosphate | 1997 |
Nonadrenergic contractile response of guinea pig portal vein to electrical field stimulation mimics response to UTP but not to ATP.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Electric Stimulation; Guanethidine; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Phentolamine; Portal Vein; Reserpine; Suramin; Tetrodotoxin; Triazines; Uridine Triphosphate | 1997 |
Extracellular ATP promotes cellular growth of renal inner medullary collecting duct cells mediated via P2u receptors.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Kidney Medulla; Kidney Tubules, Collecting; Male; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Staurosporine; Suramin; Uridine Triphosphate | 1997 |
P2 purinoceptor of the globular substance in the otoconial membrane of the guinea pig inner ear.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Enzyme Inhibitors; Estrenes; Guinea Pigs; Kinetics; Otolithic Membrane; PC12 Cells; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrrolidinones; Rats; Receptors, Purinergic P2; Saccule and Utricle; Suramin; Triazines; Type C Phospholipases; Uridine Triphosphate | 1997 |
UTP induces vascular responses in the isolated and perfused canine epicardial coronary artery via UTP-preferring P2Y receptors.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antinematodal Agents; Coronary Vessels; Diltiazem; Dogs; Female; Hexokinase; Indomethacin; Male; Protein Synthesis Inhibitors; Receptors, Purinergic P2; Saponins; Suramin; Triazines; Uridine Diphosphate; Uridine Triphosphate | 1997 |
Extracellular ATP directly gates a cation-selective channel in rabbit airway ciliated epithelial cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Barium Compounds; Cations, Divalent; Cesium; Chlorides; Cilia; Electric Conductivity; Electric Stimulation; Epithelial Cells; Extracellular Space; GTP-Binding Proteins; Ion Channel Gating; Ion Channels; Male; Mucous Membrane; Patch-Clamp Techniques; Rabbits; Receptors, Purinergic P2; Suramin; Tetraethylammonium; Trachea; Uridine Triphosphate | 1998 |
Characterization of purinergic receptor-evoked increases in intracellular Ca2+ transients in isolated human and rodent insulin-secreting cells. Purinergic receptor signalling and [Ca2+]i in human beta-cells.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cadaver; Calcium; Cells, Cultured; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Models, Biological; Receptors, Purinergic; Rodentia; Signal Transduction; Suramin; Tissue Donors; Uridine Triphosphate | 1997 |
Comparison of the actions of ATP and UTP and P(2X1) receptors in smooth muscle of the rat tail artery.
Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Kinetics; Male; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X; Suramin; Tail; Uridine Triphosphate | 1998 |
Selective inhibition of M-type potassium channels in rat sympathetic neurons by uridine nucleotide preferring receptors.
Topics: Adenine Nucleotides; Animals; Calcium Channels; Guanine Nucleotides; Hydrolysis; Ion Channel Gating; Neurons; Potassium Channel Blockers; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Suramin; Sympathetic Nervous System; Triazines; Uridine Diphosphate; Uridine Triphosphate | 1998 |
ATP activates cAMP production via multiple purinergic receptors in MDCK-D1 epithelial cells. Blockade of an autocrine/paracrine pathway to define receptor preference of an agonist.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Autocrine Communication; Cyclic AMP; Cyclooxygenase Inhibitors; Dogs; Epithelial Cells; Indomethacin; Paracrine Communication; Prostaglandins; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Signal Transduction; Suramin; Thionucleotides; Uridine Triphosphate | 1998 |
P2Y receptor subtypes differentially couple to inwardly-rectifying potassium channels.
Topics: Adenosine Triphosphate; Animals; Calcium; Chloride Channels; Electrophysiology; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Oocytes; Pertussis Toxin; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Recombinant Proteins; Suramin; Uridine Triphosphate; Virulence Factors, Bordetella; Xenopus laevis | 1998 |
Functional evidence for a novel suramin-insensitive pyrimidine receptor in rat small pulmonary arteries.
Topics: Animals; Chloride Channels; Male; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction | 1998 |
P2 receptor-mediated signal transduction in Ehrlich ascites tumor cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Amiloride; Animals; Calcium Signaling; Carcinoma, Ehrlich Tumor; Cell Size; Enzyme Inhibitors; Estrenes; Hydrogen-Ion Concentration; Mice; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrrolidinones; Receptors, Purinergic P2; Signal Transduction; Sodium-Hydrogen Exchangers; Suramin; Thapsigargin; Type C Phospholipases; Uridine Triphosphate | 1998 |
Effects of adenosine 5'-triphosphate, uridine 5'-triphosphate, adenosine 5'-tetraphosphate and diadenosine polyphosphates in guinea-pig taenia caeci and rat colon muscularis mucosae.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Colon; Dinucleoside Phosphates; Guinea Pigs; Male; Rats; Rats, Wistar; Suramin; Uridine Triphosphate | 1998 |
P2 purinoceptor localization along rat nephron and evidence suggesting existence of subtypes P2Y1 and P2Y2.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Gallic Acid; Kidney Glomerulus; Kidney Tubules, Collecting; Male; Nephrons; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Thionucleotides; Uridine Triphosphate | 1998 |
ATP-induced, P2U purinoceptor-mediated constriction of isolated, perfused mesenteric beds of the rat.
Topics: Adenosine Triphosphate; Animals; Drug Interactions; In Vitro Techniques; Male; Mesenteric Veins; Perfusion; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Uridine Triphosphate; Vasoconstriction | 1998 |
Characterization of cultured dorsal root ganglion neuron P2X receptors.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Fluorescent Dyes; Ganglia, Spinal; Gene Expression; Ion Channel Gating; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phenotype; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Receptors, Purinergic P2X4; Receptors, Purinergic P2X5; Receptors, Purinergic P2X7; Suramin; Thionucleotides; Uridine Triphosphate | 1999 |
Extracellular ATP increases [Ca2+]i in primarily cultured pig coronary smooth muscle cells via a P2Y purinoceptor subtype.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Extracellular Space; Muscle, Smooth, Vascular; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Swine; Thionucleotides; Uridine Triphosphate | 1999 |
Regulation of vascular tone by UTP and UDP in isolated rat intrapulmonary arteries.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Drug Interactions; Endothelium, Vascular; Male; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Suramin; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction; Vasodilation | 1999 |
Differential effects of adenine nucleotide analogues on shape change and aggregation induced by adnosine 5-diphosphate (ADP) in human platelets.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Cell Size; Dose-Response Relationship, Drug; Humans; Platelet Aggregation; Suramin; Thionucleotides; Trypanocidal Agents; Uridine Triphosphate | 1999 |
Nucleotide stimulation of Cl(-) secretion in the pigmented rabbit conjunctiva.
Topics: Adenosine; Animals; Chlorides; Conjunctiva; Electrophysiology; Ion Transport; Male; Mucous Membrane; Nucleotides; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Sodium; Suramin; Uridine Triphosphate | 1999 |
Two different P2Y receptors linked to steroidogenesis in bovine adrenocortical cells.
Topics: Adenosine Triphosphate; Adrenal Cortex; Animals; Calcium; Cattle; Cells, Cultured; GTP-Binding Proteins; Inositol Phosphates; Pertussis Toxin; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroids; Suramin; Uridine Triphosphate; Virulence Factors, Bordetella | 1999 |
Intercellular communication in spinal cord astrocytes: fine tuning between gap junctions and P2 nucleotide receptors in calcium wave propagation.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Calcium; Cell Communication; Cells, Cultured; Connexin 43; Gap Junctions; Heptanol; Membrane Potentials; Mice; Mice, Knockout; Patch-Clamp Techniques; Receptors, Purinergic P2; Spinal Cord; Suramin; Uridine Triphosphate | 2000 |
Evidence that rat hepatocytes co-express functional P2Y1 and P2Y2 receptors.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; DNA, Complementary; Liver; Male; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Suramin; Uridine Diphosphate; Uridine Triphosphate | 2000 |
Extracellular nucleotides activate the p38-stress-activated protein kinase cascade in glomerular mesangial cells.
Topics: Activating Transcription Factor 2; Adenosine Triphosphate; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; GTP-Binding Proteins; Imidazoles; Isoenzymes; Mitogen-Activated Protein Kinases; Nucleotides; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Stress, Physiological; Suramin; Transcription Factors; Uridine Triphosphate | 2000 |
Suramin blocks nucleotide triphosphate binding to ribosomal protein L3 from Trypanoplasma borreli.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Animals; Circular Dichroism; Cloning, Molecular; Evolution, Molecular; Guanosine Triphosphate; Kinetoplastida; Molecular Sequence Data; Nucleotides; Protein Binding; Protein Structure, Tertiary; Protozoan Proteins; Radioligand Assay; Recombinant Fusion Proteins; Ribosomal Protein L3; Ribosomal Proteins; Ribosomes; Sequence Alignment; Sequence Deletion; Sequence Homology, Amino Acid; Suramin; Surface Plasmon Resonance; Trypanocidal Agents; Uridine Triphosphate | 2000 |
P2Y2 receptor elevates intracellular calcium concentration in rabbit eye suprachoroid.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Choroid; Cytophotometry; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Female; Fluorescent Dyes; Fura-2; Gallic Acid; Male; Phosphodiesterase Inhibitors; Pyrrolidinones; Rabbits; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Sarcoplasmic Reticulum; Statistics as Topic; Suramin; Thapsigargin; Time Factors; Type C Phospholipases; Uridine Triphosphate | 1999 |
Extracellular ATP increases [Ca(2+)](i) in distal tubule cells. II. Activation of a Ca(2+)-dependent Cl(-) conductance.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Line; Cell Membrane; Cell Polarity; Chelating Agents; Chloride Channels; Chlorides; Electric Conductivity; Iodine Radioisotopes; Ionomycin; Kidney Tubules, Distal; Kinetics; Male; Models, Biological; Nitrobenzenes; Rabbits; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Uridine Triphosphate; Xanthines | 2000 |
Multiple P2Y receptors mediate contraction in guinea pig mesenteric vein.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Male; Mesenteric Artery, Inferior; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Chloride; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Pyrimidine Nucleotides; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin; Uridine Triphosphate | 2000 |
Coexpression of several types of metabotropic nucleotide receptors in single cerebellar astrocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Calcium; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Intracellular Fluid; Pertussis Toxin; Protein Kinase C; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Stimulation, Chemical; Suramin; Thionucleotides; Uridine Triphosphate; Virulence Factors, Bordetella | 2000 |
Antiproliferative effect of UTP on human arterial and venous smooth muscle cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Calcium; Cell Division; Cells, Cultured; Humans; Inositol 1,4,5-Trisphosphate; Mammary Arteries; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Platelet Aggregation Inhibitors; Platelet-Derived Growth Factor; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Saphenous Vein; Suramin; Thymidine; Tritium; Type C Phospholipases; Uridine Triphosphate | 2000 |
Properties of P2X and P2Y receptors are dependent on artery diameter in the rat mesenteric bed.
Topics: Adenosine Triphosphate; Animals; Calcium; Dose-Response Relationship, Drug; Immunohistochemistry; In Vitro Techniques; Male; Mesenteric Arteries; Phenylephrine; Potassium Chloride; Protein Subunits; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Uridine Triphosphate; Vasoconstriction | 2000 |
Potentiation of cytokine induction of group IIA phospholipase A(2) in rat mesangial cells by ATP and adenosine via the A2A adenosine receptor.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Blotting, Northern; Cells, Cultured; Enzyme Induction; Enzyme Inhibitors; Glomerular Mesangium; Group II Phospholipases A2; Interleukin-1; Phospholipases A; Purinergic P2 Receptor Antagonists; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; RNA, Messenger; Signal Transduction; Suramin; Triazines; Triazoles; Uridine Triphosphate; Vasodilator Agents | 2001 |
Analysis of purine- and pyrimidine-induced vascular responses in the isolated rat cerebral arteriole.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Arterioles; Cerebral Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroprusside; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y2; Suramin; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction; Vasodilation | 2001 |
The effects of P2Y receptor agonists and adenosine on prostaglandin production by the guinea-pig uterus.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Endometrium; Female; Guinea Pigs; Myometrium; Prostaglandins; Purinergic P2 Receptor Agonists; Suramin; Uridine Triphosphate | 2001 |
Effects of ATP on intracellular calcium dynamics of the perineurium of peripheral nerve bundles.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anesthetics, Local; Animals; Antineoplastic Agents; Calcium; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Lidocaine; Male; Microscopy, Confocal; Peripheral Nerves; Rats; Rats, Inbred WKY; Sciatic Nerve; Suramin; Tetraethylammonium; Tetrodotoxin; Thapsigargin; Triazines; Uridine Triphosphate | 2000 |
Purine and pyrimidine nucleotide-sensitive phospholipase A(2) in ampulla from frog semicircular canal.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Colforsin; Enzyme Activation; Enzyme Inhibitors; Estrenes; Indoles; Isoquinolines; Kinetics; Maleimides; Models, Biological; Phospholipases A; Purine Nucleotides; Pyrimidine Nucleotides; Pyrrolidinones; Rana ridibunda; Receptor Cross-Talk; Receptors, Purinergic P2; Semicircular Canals; Sulfonamides; Suramin; Uridine Triphosphate | 2001 |
Purinergic regulation of intracellular Ca2+ concentration of rat pituitary folliculo-stellate cells in primary culture.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Enzyme Inhibitors; Estrenes; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Fluid; Male; Membrane Proteins; Pituitary Gland, Anterior; Purinergic P2 Receptor Antagonists; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ryanodine; Suramin; Thapsigargin; Type C Phospholipases; Uridine Triphosphate | 2001 |
Pharmacological characterisation of pyrimidinoceptor responses in NG108-15 cells.
Topics: Adenosine; Analgesics; Animals; Antineoplastic Agents; Cell Line; Inositol Phosphates; Mice; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Suramin; Type C Phospholipases; Uridine Diphosphate; Uridine Triphosphate | 2001 |
Molecular cloning and characterization of the mouse P2Y4 nucleotide receptor.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antineoplastic Agents; Cloning, Molecular; Dose-Response Relationship, Drug; Humans; Inositol 1,4,5-Trisphosphate; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Suramin; Transfection; Triazines; Tumor Cells, Cultured; Uridine Triphosphate | 2001 |
Apical P2Y4 purinergic receptor controls K+ secretion by vestibular dark cell epithelium.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Ear, Inner; Epithelium; Female; Gerbillinae; Humans; Membrane Potentials; Molecular Sequence Data; Potassium; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Suramin; Uridine Diphosphate; Uridine Triphosphate | 2001 |
Dehydroepiandrosterone sulfate (DHEAS) suppresses P2X purinoceptor-coupled responses in PC12 cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Cytosol; Dehydroepiandrosterone Sulfate; Dopamine Antagonists; Drug Synergism; Osmolar Concentration; PC12 Cells; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X; Sodium; Suramin; Uridine Triphosphate | 2001 |
ATP induces Ca(2+) signaling in human chondrons cultured in three-dimensional agarose films.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Antineoplastic Agents; Calcium Signaling; Cells, Cultured; Chondrocytes; Dose-Response Relationship, Drug; Fura-2; Humans; Sepharose; Suramin; Uridine Triphosphate | 2001 |
P2X2 receptor mediates stimulation of parasensory cation absorption by cochlear outer sulcus cells and vestibular transitional cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Cochlea; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Flufenamic Acid; Gadolinium; Gerbillinae; Hearing; In Vitro Techniques; Ion Channels; Ion Transport; Microelectrodes; Physical Stimulation; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Suramin; Uridine Diphosphate; Uridine Triphosphate; Vestibule, Labyrinth; Vibration | 2001 |
Regulation of transcervical permeability by two distinct P2 purinergic receptor mechanisms.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Calcium; Calcium Signaling; Cell Membrane Permeability; Cells, Cultured; Cervix Uteri; Chelating Agents; Egtazic Acid; Epithelial Cells; Female; Guanosine Triphosphate; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Receptors, Purinergic P2Y2; Suramin; Uridine Triphosphate | 2002 |
Nucleotide receptors involved in UTP-induced rat arterial smooth muscle cell migration.
Topics: Animals; Cell Movement; Cells, Cultured; Gene Expression Regulation; Muscle, Smooth, Vascular; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; Suramin; Uridine Diphosphate; Uridine Triphosphate | 2002 |
Enhanced IPC by activation of pertussis toxin-sensitive and -insensitive G protein-coupled purinoceptors.
Topics: Adenosine; Adenosine Triphosphate; Animals; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Indoles; Ischemic Preconditioning; Male; Maleimides; Myocardial Ischemia; Myocardial Reperfusion Injury; Pertussis Toxin; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Uridine Triphosphate; Ventricular Function, Left; Virulence Factors, Bordetella | 2002 |
Purinergic receptor signaling at the basolateral membrane of macula densa cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzofurans; Calcium; Cytosol; Dose-Response Relationship, Drug; Estrenes; Female; Fura-2; Imidazoles; Kidney Glomerulus; Microscopy, Confocal; Pyrrolidinones; Rabbits; Receptors, Purinergic; Signal Transduction; Suramin; Thionucleotides; Uridine Triphosphate | 2002 |
Adenosine 5'-triphosphate-evoked calcium responses in terminal Schwann cells of lanceolate sensory endings isolated from rat vibrissae.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Dose-Response Relationship, Drug; Fluorescent Dyes; Intracellular Fluid; Male; Mechanoreceptors; Neurons, Afferent; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; S100 Proteins; Schwann Cells; Signal Transduction; Suramin; Touch; Uridine Triphosphate; Vibrissae | 2002 |
Extracellular ATP and UTP activate the protein kinase B/Akt cascade via the P2Y(2) purinoceptor in renal mesangial cells.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Apoptosis; Arachidonic Acid; Blotting, Western; Cell Division; Cells, Cultured; Enzyme Activation; Extracellular Space; Glomerular Mesangium; Isoenzymes; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Uridine Triphosphate | 2002 |
ATP induces leukemia inhibitory factor mRNA in cultured rat astrocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Central Nervous System; Dose-Response Relationship, Drug; Fetus; Growth Inhibitors; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Microglia; Neurons; Neurotransmitter Agents; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Receptors, Purinergic; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Messenger; Suramin; Uridine Triphosphate | 2002 |
Effects of luminal flow and nucleotides on [Ca(2+)](i) in rabbit cortical collecting duct.
Topics: Adenosine Triphosphate; Animals; Boron Compounds; Calcium; Calcium Channels, L-Type; Female; Gap Junctions; Kidney Cortex; Kidney Tubules, Collecting; Nifedipine; Nucleotides; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Suramin; Thapsigargin; Uridine Triphosphate | 2002 |
Purinergic and muscarinic modulation of the cell cycle and calcium signaling in the chick retinal ventricular zone.
Topics: Aniline Compounds; Animals; Benzimidazoles; Biological Clocks; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Cycle; Cell Division; Chick Embryo; Cholinergic Agonists; Excitatory Amino Acid Agonists; Fluorescent Dyes; In Vitro Techniques; Intracellular Fluid; Microscopy, Confocal; Mitosis; Muscarinic Antagonists; Neurotransmitter Agents; Purinergic Agonists; Receptors, Muscarinic; Receptors, Purinergic; Retina; Suramin; Uridine Triphosphate; Xanthenes | 2002 |
Human Ntera-2/D1 neuronal progenitor cells endogenously express a functional P2Y1 receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Antineoplastic Agents; Blotting, Western; Calcium; Cell Membrane; Cells, Cultured; Cyclic AMP; Fluorescence; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Membrane Proteins; Mitogen-Activated Protein Kinases; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Suramin; Thionucleotides; Uridine Triphosphate | 2002 |
P2 purinoceptors regulate calcium-activated chloride and fluid transport in 31EG4 mammary epithelia.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Biological Transport; Body Fluids; Calcium; Cell Line; Chloride Channels; Chlorides; Electric Impedance; Electrophysiology; Epithelial Cells; Female; Intracellular Membranes; Mammary Glands, Animal; Mice; Osmolar Concentration; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Suramin; Uridine Triphosphate | 2003 |
Differential properties of astrocyte calcium waves mediated by P2Y1 and P2Y2 receptors.
Topics: Adenosine Triphosphate; Animals; Apyrase; Astrocytes; Astrocytoma; Calcium; Calcium Signaling; Cells, Cultured; Enzyme Inhibitors; Humans; Physical Stimulation; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord; Suramin; Transfection; Uridine Triphosphate | 2003 |
P2Y(2) receptor elicits PAS-positive glycoprotein secretion from rabbit conjunctival goblet cells in vivo.
Topics: Adenosine Triphosphate; Animals; Conjunctiva; Glycoproteins; Goblet Cells; Male; Mucins; Periodic Acid-Schiff Reaction; Photomicrography; Pyridoxal Phosphate; Rabbits; Receptors, Purinergic P2; Suramin; Time Factors; Uridine Triphosphate | 2003 |
Extended pharmacological profiles of rat P2Y2 and rat P2Y4 receptors and their sensitivity to extracellular H+ and Zn2+ ions.
Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Protons; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Suramin; Uridine Triphosphate; Xenopus; Zinc | 2003 |
ATP and UTP responses of cultured rat aortic smooth muscle cells revisited: dominance of P2Y2 receptors.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Cells, Cultured; Clone Cells; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Purinergic P2; Species Specificity; Suramin; Uridine Triphosphate | 2003 |
Structure-activity relationships of analogues of NF449 confirm NF449 as the most potent and selective known P2X1 receptor antagonist.
Topics: Adenosine Triphosphate; Animals; Benzenesulfonates; Cell Line; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Ileum; Lethal Dose 50; Male; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X; Structure-Activity Relationship; Suramin; Uridine Triphosphate; Vas Deferens | 2004 |
Purinergic receptors coupled to intracellular Ca2+ signals and exocytosis in rat prostate neuroendocrine cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cell Membrane; Electric Capacitance; Electrophysiology; Exocytosis; Male; Microscopy, Fluorescence; Neurosecretory Systems; Prostate; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Uridine Diphosphate; Uridine Triphosphate | 2004 |
Oscillatory calcium responses mediated by P2Y2 purinergic receptors in terminal Schwann cells of longitudinal lanceolate endings isolated from rat vibrissae.
Topics: Adenosine Triphosphate; Aniline Compounds; Animals; Calcium; Calcium Signaling; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Immunohistochemistry; In Vitro Techniques; Male; Microscopy, Confocal; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Schwann Cells; Suramin; Time Factors; Triazines; Uridine Diphosphate; Uridine Triphosphate; Vibrissae; Xanthenes | 2004 |
Nucleotide-mediated mucin secretion from differentiated human bronchial epithelial cells.
Topics: Adenosine Triphosphate; Binding, Competitive; Bronchi; Calcium; Carcinogens; Cell Culture Techniques; Cell Differentiation; Chelating Agents; Epithelial Cells; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Lectins; Mucins; Naphthalenes; Pertussis Toxin; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Signal Transduction; Suramin; Tetradecanoylphorbol Acetate; Uridine Triphosphate | 2004 |
Expression of P2Y2 purinoceptors in MCG 101 murine sarcoma cells, and HT-29 human colon carcinoma cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Mice; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Sarcoma; Suramin; Time Factors; Uridine Triphosphate | 2004 |
Uridine 5'-triphosphate stimulates alveolar fluid clearance in the isolated rat lungs.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Drug Interactions; Extravascular Lung Water; Glyburide; In Vitro Techniques; Isoproterenol; Male; Nitrobenzoates; Propranolol; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Suramin; Uridine Triphosphate | 2004 |
Evidence for P2Y1, P2Y2, P2Y6 and atypical UTP-sensitive receptors coupled to rises in intracellular calcium in mouse cultured superior cervical ganglion neurons and glia.
Topics: Animals; Calcium; Cells, Cultured; Female; Fluorescent Dyes; Male; Mice; Mice, Inbred C57BL; Neuroglia; Neurons; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; Superior Cervical Ganglion; Suramin; Uridine Diphosphate; Uridine Triphosphate | 2004 |
Varicosity-Schwann cell interactions mediated by ATP in the mouse vas deferens.
Topics: Adenosine Triphosphate; Adrenergic Fibers; Aniline Compounds; Animals; Caffeine; Calcium; Cell Count; Drug Interactions; Electric Stimulation; Estrenes; Evoked Potentials; Fluorescent Dyes; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Organic Chemicals; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Pyrrolidinones; Quinazolines; S100 Proteins; Schwann Cells; Suramin; Time Factors; Triazoles; Uridine Triphosphate; Vas Deferens; Xanthenes | 2005 |
Secretion of ATP from Schwann cells in response to uridine triphosphate.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Animals, Newborn; Benzophenanthridines; Botulinum Toxins; Botulinum Toxins, Type A; Brefeldin A; Calcium; Cyclic AMP-Dependent Protein Kinases; Cytochalasin D; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Estrenes; Furosemide; Glyburide; Glycyrrhetinic Acid; Guanosine Triphosphate; Immunohistochemistry; Isoquinolines; Microscopy, Confocal; Nucleic Acid Synthesis Inhibitors; Phenanthridines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Synthesis Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Schwann Cells; Sciatic Nerve; Sulfonamides; Suramin; Thapsigargin; Time Factors; Type C Phospholipases; Uridine Triphosphate | 2005 |
Involvement of uracil nucleotides in protection of cardiomyocytes from hypoxic stress.
Topics: Adenosine Triphosphate; Animals; Blotting, Western; Calcium; Calcium Signaling; Cardiotonic Agents; Cell Hypoxia; Cells, Cultured; Enzyme Activation; Immunohistochemistry; L-Lactate Dehydrogenase; Myocytes, Cardiac; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Stress, Physiological; Suramin; Time Factors; Triazines; Type C Phospholipases; Uracil Nucleotides; Uridine; Uridine Diphosphate; Uridine Triphosphate | 2005 |
Mechanisms of ATP action on motor nerve terminals at the frog neuromuscular junction.
Topics: Adenosine; Adenosine Triphosphate; Animals; Anura; Arachidonic Acid; Barium; Calcium; Calcium Channel Blockers; Drug Interactions; Electrophysiology; Enzyme Inhibitors; In Vitro Techniques; Ionomycin; Ionophores; Ketones; Membrane Potentials; Motor Neurons; Neural Inhibition; Neuromuscular Junction; Potassium; Potassium Channel Blockers; Sucrose; Suramin; Uridine Triphosphate | 2005 |
Changes in purinergic signalling in developing and ageing rat tail artery: importance for temperature control.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Arteries; Dose-Response Relationship, Drug; Electric Stimulation; Immunohistochemistry; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Regional Blood Flow; Signal Transduction; Suramin; Tail; Thionucleotides; Uridine Triphosphate | 2006 |
Extracellular ATP stimulates NO production in rat thick ascending limb.
Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Fluorescein; Fluorescent Dyes; Hydrolysis; Loop of Henle; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Uridine Triphosphate | 2006 |
Schwann cells in rat vascular autonomic nerves activated via purinergic receptors.
Topics: Adenosine; Adenosine Triphosphate; Animals; Autonomic Nervous System; Calcium; Quinazolines; Rats; Rats, Wistar; Receptors, Purinergic; Schwann Cells; Splanchnic Circulation; Suramin; Triazoles; Uridine Triphosphate | 2006 |
ATP stimulates interleukin-6 production via P2Y receptors in human HaCaT keratinocytes.
Topics: Adenosine Triphosphate; Calcium; Cell Line; Dactinomycin; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme-Linked Immunosorbent Assay; Gene Expression; Humans; Indoles; Interleukin-6; Keratinocytes; Maleimides; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Mechanical; Suramin; Time Factors; Uridine Triphosphate | 2006 |
Reactive blue 2, an antagonist of rat P2Y4, increases K+ secretion in rat cochlea strial marginal cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Ion Transport; Perilymph; Potassium; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Sodium-Potassium-Exchanging ATPase; Stria Vascularis; Suramin; Triazines; Uridine Triphosphate; Vibration | 2006 |
P2 purinergic receptors signal to STAT3 in astrocytes: Difference in STAT3 responses to P2Y and P2X receptor activation.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Serine; Signal Transduction; STAT3 Transcription Factor; Suramin; Theophylline; Thymidine; Time Factors; Tritium; Uridine Triphosphate | 2006 |
Uracil nucleotides stimulate human neural precursor cell proliferation and dopaminergic differentiation: involvement of MEK/ERK signalling.
Topics: Adenine Nucleotides; Blotting, Western; Cell Count; Cell Death; Cell Differentiation; Cell Proliferation; Dopamine; Electrophysiology; Extracellular Signal-Regulated MAP Kinases; Fluorescent Antibody Technique; Humans; Mesencephalon; Nerve Tissue Proteins; Neurons; Oligonucleotide Array Sequence Analysis; Patch-Clamp Techniques; Pyridoxal Phosphate; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stem Cells; Suramin; Uracil Nucleotides; Uridine Triphosphate | 2006 |
Evidence for the expression of multiple uracil nucleotide-stimulated P2 receptors coupled to smooth muscle contraction in porcine isolated arteries.
Topics: Animals; Blotting, Western; Coronary Vessels; Dose-Response Relationship, Drug; Ear; Gene Expression; In Vitro Techniques; Muscle, Smooth, Vascular; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Suramin; Swine; Uracil Nucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction | 2007 |
Activation-dependent trafficking of NTPDase2 in Chinese hamster ovary cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Green Fluorescent Proteins; Hydrolysis; Intracellular Fluid; Microscopy, Confocal; Protein Transport; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Recombinant Fusion Proteins; Suramin; Time Factors; Transfection; Uridine Diphosphate; Uridine Triphosphate | 2007 |
Otopetrin 1 activation by purinergic nucleotides regulates intracellular calcium.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cell Line; Chlorocebus aethiops; COS Cells; Endoplasmic Reticulum; Green Fluorescent Proteins; Humans; Inositol 1,4,5-Trisphosphate; Membrane Proteins; Nucleotides; Osteosarcoma; Rats; Receptors, Purinergic P2; Suramin; Uridine Triphosphate | 2007 |
Involvement of apical P2Y2 receptor-regulated CFTR activity in muscarinic stimulation of Cl(-) reabsorption in rat submandibular gland.
Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Fluorescent Antibody Technique; Male; Potassium; Propranolol; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Salivary Ducts; Salivary Proteins and Peptides; Salivation; Sodium; Submandibular Gland; Suramin; Uridine Triphosphate | 2008 |
ATP activates P2x receptors and requires extracellular Ca(++) participation to modify outer hair cell nonlinear capacitance.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Calcium; Chelating Agents; Egtazic Acid; Electric Capacitance; Guinea Pigs; Hair Cells, Auditory, Outer; Membrane Potentials; Patch-Clamp Techniques; Potassium; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Signal Transduction; Sodium; Suramin; Time Factors; Uridine Triphosphate | 2008 |
Luminal ATP-induced contraction of rabbit pulmonary arteries and role of purinoceptors in the regulation of pulmonary arterial pressure.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Calcium Signaling; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Female; Hypoxia; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Perfusion; Pulmonary Artery; Pulmonary Circulation; Rabbits; Receptors, Purinergic P2; Respiration, Artificial; Spectrometry, Fluorescence; Suramin; Uridine Triphosphate; Vasoconstriction; Vasodilation; Video Recording | 2008 |
Pharmacological properties of P2 receptors on rat otic parasympathetic ganglion neurons.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Ganglia, Parasympathetic; Rats; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Suramin; Uridine Triphosphate | 2008 |
P2Y receptors mediate Ca2+ signaling in duodenocytes and contribute to duodenal mucosal bicarbonate secretion.
Topics: Adenosine Diphosphate; Aminoquinolines; Animals; Bicarbonates; Boron Compounds; Calcium Channel Blockers; Calcium Signaling; Cell Line; Dogs; Duodenum; Epithelial Cells; Estrenes; Female; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestinal Secretions; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Nifedipine; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Pyrrolidinones; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Time Factors; Uridine Triphosphate | 2009 |
Purinergic receptor activation evokes neurotrophic factor neuropeptide Y release from neonatal mouse olfactory epithelial slices.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Animals, Newborn; Collodion; Immunoassay; Immunohistochemistry; In Vitro Techniques; Mice; Neuropeptide Y; Olfactory Mucosa; Purinergic Antagonists; Pyridoxal Phosphate; Receptors, Purinergic; Suramin; Uridine Triphosphate | 2009 |
Uridine-5'-triphosphate protects against hepatic- ischemic/reperfusion injury in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Blood Pressure; Caspase 3; Cell Hypoxia; Cells, Cultured; Hepatocytes; L-Lactate Dehydrogenase; Liver; Male; Mice; Reperfusion Injury; Suramin; Uridine Triphosphate; Vena Cava, Inferior | 2009 |
Activation of purinergic receptors induces proliferation and neuronal differentiation in Swiss Webster mouse olfactory epithelium.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Biomarkers; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Male; Mice; Nerve Regeneration; Neurogenesis; Olfactory Mucosa; Organ Culture Techniques; Proliferating Cell Nuclear Antigen; Purinergic Agonists; Purinergic Antagonists; Receptors, Purinergic; Sensory Receptor Cells; Stem Cells; Suramin; Uridine Triphosphate | 2009 |
Promoting MPhi transepithelial migration by stimulating the epithelial cell P2Y(2) receptor.
Topics: Adenosine Triphosphate; Animals; Antibodies; Caco-2 Cells; Cell Adhesion; Cell Line; Cell Movement; Electric Impedance; Epithelial Cells; Gene Expression; Humans; Intercellular Adhesion Molecule-1; Intestinal Mucosa; Macrophages; Mice; Mice, Inbred Strains; Neutrophils; NF-kappa B; Nucleotides; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; U937 Cells; Uridine Triphosphate | 2009 |
Spontaneous oscillations in intracellular Ca(2+) concentration via purinergic receptors elicit transient cell swelling in rat parotid ducts.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Atropine; Calcium Signaling; Cell Size; Fluorescent Dyes; In Vitro Techniques; Male; Microscopy, Electron, Transmission; Microscopy, Fluorescence, Multiphoton; Muscarinic Antagonists; Parotid Gland; Phentolamine; Rats; Rats, Wistar; Receptors, Purinergic; Salivary Ducts; Signal Processing, Computer-Assisted; Suramin; Time Factors; Uridine Triphosphate | 2009 |
The P2Y2 receptor sensitizes mouse bladder sensory neurons and facilitates purinergic currents.
Topics: Action Potentials; Animals; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y2; Sensory Receptor Cells; Suramin; Uridine Triphosphate; Urinary Bladder | 2010 |
P2Y2 receptors mediate ATP-induced resensitization of TRPV1 expressed by kidney projecting sensory neurons.
Topics: Animals; Capsaicin; Drug Interactions; Ganglia, Spinal; Ion Channels; Kidney; Male; Mercaptoethanol; Neurons; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Sensory Receptor Cells; Suramin; TRPV Cation Channels; Uridine Triphosphate | 2010 |
The P2Y(2) nucleotide receptor mediates tissue factor expression in human coronary artery endothelial cells.
Topics: Adenosine Triphosphate; Antinematodal Agents; Cell Line, Tumor; Coronary Vessels; Endothelial Cells; Gene Expression Regulation; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Thromboplastin; Uridine Triphosphate | 2011 |
Extracellular ATP signaling in equine digital blood vessels.
Topics: Adenosine Triphosphate; Animals; Arteries; Electric Stimulation; Female; Horses; In Vitro Techniques; Male; Methoxamine; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin; Uridine Triphosphate; Vasoconstriction; Vasoconstrictor Agents; Veins | 2013 |
Inhibition of G protein-coupled P2Y2 receptor induced analgesia in a rat model of trigeminal neuropathic pain.
Topics: Action Potentials; Animals; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Face; Gene Expression Regulation; Hyperalgesia; Male; Pain; Potassium Channels; Purinergic P2Y Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2Y2; Sensory Receptor Cells; Skin; Suramin; Trigeminal Ganglion; Trigeminal Nerve Diseases; Uridine Triphosphate | 2014 |
[The different contraction between rat gastric longitudinal and circular smooth muscle induced by extracellular nucleotides].
Topics: Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Indomethacin; Muscle Contraction; Muscle, Smooth; Nucleotides; Rats; Suramin; Uridine Triphosphate | 2014 |
Pyrimidinergic Receptor Activation Controls Toxoplasma gondii Infection in Macrophages.
Topics: Animals; Apoptosis; Cells, Cultured; Female; Host-Parasite Interactions; Macrophages; Macrophages, Peritoneal; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nitric Oxide; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Reactive Oxygen Species; Receptors, Purinergic P2Y; Suramin; Toxoplasma; Uridine Diphosphate; Uridine Triphosphate | 2015 |
Enhancement of acid-sensing ion channel activity by metabotropic P2Y UTP receptors in primary sensory neurons.
Topics: Acid Sensing Ion Channels; Acidosis; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Ganglia, Spinal; Male; Membrane Potentials; Pain; Pain Measurement; Protons; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2Y1; Sensory Receptor Cells; Signal Transduction; Suramin; Uridine Triphosphate | 2016 |
Altered urothelial ATP signaling in a major subset of human overactive bladder patients with pyuria.
Topics: Adenosine Triphosphate; Carbenoxolone; Female; Humans; Male; Purinergic P2 Receptor Antagonists; Pyuria; Signal Transduction; Suramin; Uridine Triphosphate; Urinary Bladder; Urinary Bladder, Overactive; Urothelium | 2016 |