Page last updated: 2024-08-16

suramin and pentamidine

suramin has been researched along with pentamidine in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-199020 (30.77)18.7374
1990's3 (4.62)18.2507
2000's20 (30.77)29.6817
2010's20 (30.77)24.3611
2020's2 (3.08)2.80

Authors

AuthorsStudies
Barszcz, T; Bhattacharya, G; Brun, R; Delfín, D; Herman, J; Mollet, M; Riccio, G; Salem, MM; Werbovetz, KA1
Salem, MM; Werbovetz, KA2
Delfín, DA; Endeshaw, MM; Fotie, J; George, TG; Li, C; Mahasenan, KV; Morgan, RE; Mukherjee, MS; Werbovetz, KA; Yakovich, AJ1
Adelaida Gomez, M; Bohle, DS; Fotie, J; Nzimiro, S; Olivier, M1
Lombardo, F; Obach, RS; Waters, NJ1
Ishiyama, A; Kinoshita, E; Kitajima, M; Kogure, N; Omura, S; Otoguro, K; Takayama, H; Toriizuka, Y; Yamada, H1
Büchold, C; Gelhaus, C; Gut, J; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Stempka, M1
Breuning, A; Büchold, C; Degel, B; Gelhaus, C; Gut, J; Heppner, S; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rath, J; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Schulz, F; Stempka, M; Stich, A1
Brun, R; Fotie, J; Gershkovich, P; He, S; Liu, Q; Patrick, DA; Premalatha, K; Reid, CS; Tidwell, RR; Wang, MZ; Wasan, KM; Wenzler, T; Werbovetz, KA1
Alley, MR; Chen, G; Ding, D; Gao, G; Jacobs, R; Li, D; Meng, Q; Nare, B; Plattner, JJ; Rock, F; Wang, Q; Zhao, Y; Zhou, H1
Clayton, C; De Muylder, G; Gerwick, L; Helbig, C; Knudsen, GM; Linington, RG; Mackey, ZB; Mascuch, SM; McKerrow, JH; Sanchez, LM1
Aoyagi, Y; Fujiwara, K; Fukaya, H; Hitotsuyanagi, Y; Ishiyama, A; Iwatsuki, M; Ōmura, S; Otoguro, K; Sugawara, N; Takeya, K; Yamada, H; Yamazaki, A; Yano, R1
Jacobs, RT; Meng, Q; Nare, B; Wu, P; Zhang, J; Zhou, H1
Conti, P; Cordeiro da Silva, A; Cosconati, S; Costi, MP; Cullia, G; De Micheli, C; Eadsforth, TC; Hunter, WN; Lo Presti, L; Luciani, R; Marinelli, L; Novellino, E; Pinto, A; Tamborini, L1
Mattock, NM; Peters, W1
Thomson, KD1
Brun, R; Kunz, C1
Baeriswyl, S; Brun, R; Kunz, C1
Berman, JD1
Jefferies, D; Jenni, L1
Lefrock, JL; Smith, BR1
Gutteridge, WE1
Balber, AE; Frommel, TO1
Williamson, J1
Dukes, P1
Barrett-Connor, E1
Boa Yapo, F; Doua, F1
Milord, F; Pépin, J1
Coetzer, TH; Jones, R; Lonsdale-Eccles, JD; Morty, RE; Nickel, P; Pike, RN; Troeberg, L1
Barrett, MP; Barrett, SV1
Bouteille, B; Dumas, M1
de Koning, HP1
Etchegorry, MG; Helenport, JP; Jannin, J; Legros, D; Pecoul, B1
Kager, PA1
Nok, AJ1
Docampo, R; Moreno, SN1
BAGET, J; COSAR, C; DUCROT, R; GAILLIOT, P1
MONTEZIN, G; SCHNEIDER, J1
CAUSSE, M; MASSEGUIN, A; RICOSSE, M1
NEUJEAN, G1
HAWKING, F; SEN, AB1
ROLLO, IM; WILLIAMSON, J1
Rudenko, G; Sheader, K; te Vruchte, D1
GUIMARAES, JL; LOURIE, EM1
Berbari, EF; Jacobson, KM; Kumar, N; Orenstein, R; Uslan, DZ1
De Koning, HP; Dogruel, M; Rodgers, J; Sanderson, L; Thomas, SA1
Blum, J; Brun, R; Burri, C; Chappuis, F1
Schlitzer, M1
Chiodini, PL; Macdonald, D; Nadjm, B; Van Tulleken, C1
Arafa, RK; Boykin, DW; Brun, R; Gillingwater, K; Ismail, MA; Kumar, A; Stephens, CE; Tidwell, RR1
Alsford, S; Baker, N; Berriman, M; Eckert, S; Field, MC; Glover, L; Horn, D; Leung, KF; Sanchez-Flores, A; Turner, DJ1
Göbel, T; Göbels, S; Häussinger, D; Müller-Stöver, I; Richter, J; Westenfeld, R1
Bucheton, B; Courtois, P; Cuny, G; Daulouède, S; Dethoua, M; Nzoumbou-Boko, R; Semballa, S; Truc, P; Vincendeau, P1
Bellera, CL; Benaim, G; Carrillo, C; Romano, PS; Sbaraglini, ML; Talevi, A; Vanrell, MC1
Chiodini, PL; Fink, D; Hedley, L; Sparkes, D1
Castro, P; Chaguaceda, C; Fernández, S; Gascón, J; Gómez-Junyent, J; Mas, J; Muñoz, J; Pellicé, M; Pinazo, MJ1
Hanssen, JLJ; Scheper, H; van Lieshout, L; Visser, LG; Wijsman, CA1
Chen, JX; Chen, MX; Chen, XL; Chen, ZY; Lin, YY; Liu, Q; Xie, HG; Zhang, Y; Zheng, H; Zhou, XN1
Alsford, S; Baker, N; Dominicus, C; Glover, L; Horn, D; Hutchinson, S; Thomas, JA; Trenaman, A1
Kennedy, PGE; Rodgers, J1
Auma, JE; Chemuliti, JK; Gitonga, PK; Kurgat, RK; Mdachi, RE; Murilla, GA; Ndung'u, K; Ngae, GN; Thuita, JK; Thungu, DK1
Alghamdi, AH; Campagnaro, GD; de Koning, HP; Natto, MJ; Ungogo, MA1

Reviews

9 review(s) available for suramin and pentamidine

ArticleYear
Existing chemotherapy and its limitations.
    British medical bulletin, 1985, Volume: 41, Issue:2

    Topics: Chagas Disease; Gentian Violet; Humans; Melarsoprol; Nifurtimox; Nitroimidazoles; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African

1985
Drugs for the treatment of parasitic infection.
    The Medical clinics of North America, 1982, Volume: 66, Issue:1

    Topics: Antimony; Bithionol; Chloroquine; Diethylcarbamazine; Humans; Mebendazole; Melarsoprol; Metronidazole; Niclosamide; Niridazole; Oxamniquine; Parasitic Diseases; Pentamidine; Piperazines; Primaquine; Pyrantel Pamoate; Pyrimethamine; Suramin; Thiabendazole; Trichlorfon

1982
The treatment of human African trypanosomiasis.
    Advances in parasitology, 1994, Volume: 33

    Topics: Animals; Diminazene; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

1994
Transporters in African trypanosomes: role in drug action and resistance.
    International journal for parasitology, 2001, May-01, Volume: 31, Issue:5-6

    Topics: Africa South of the Sahara; Animals; Arsenicals; Biological Transport; Eflornithine; Humans; Nitroimidazoles; Pentamidine; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African

2001
Arsenicals (melarsoprol), pentamidine and suramin in the treatment of human African trypanosomiasis.
    Parasitology research, 2003, Volume: 90, Issue:1

    Topics: Animals; Drug Resistance; HIV; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2003
Current chemotherapy of human African trypanosomiasis.
    Parasitology research, 2003, Volume: 90 Supp 1

    Topics: Animals; Eflornithine; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African

2003
[Agents for the treatment of African sleeping sickness. Those developed in the last century].
    Pharmazie in unserer Zeit, 2009, Volume: 38, Issue:6

    Topics: Animals; Eflornithine; History, 20th Century; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African

2009
Neglected Tropical Protozoan Diseases: Drug Repositioning as a Rational Option.
    Current topics in medicinal chemistry, 2016, Volume: 16, Issue:19

    Topics: Antiprotozoal Agents; Chagas Disease; Drug Repositioning; Humans; Leishmaniasis; Neglected Diseases; Pentamidine; Protein Kinase Inhibitors; Suramin; Trypanosomiasis, African

2016
Clinical and Neuropathogenetic Aspects of Human African Trypanosomiasis.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Animals; Antiprotozoal Agents; Blood-Brain Barrier; Brain; Delayed Diagnosis; Humans; Incidence; Neglected Diseases; Pentamidine; Severity of Illness Index; Suramin; Treatment Outcome; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2019

Other Studies

56 other study(ies) available for suramin and pentamidine

ArticleYear
Synthesis and antitubulin activity of N1- and N4-substituted 3,5-dinitro sulfanilamides against African trypanosomes and Leishmania.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Animals; Cell Line; Leishmania donovani; Structure-Activity Relationship; Sulfanilamides; Trypanocidal Agents; Trypanosoma brucei brucei; Tubulin; Tubulin Modulators

2004
Antiprotozoal compounds from Psorothamnus polydenius.
    Journal of natural products, 2005, Volume: 68, Issue:1

    Topics: Animals; Antiprotozoal Agents; Chlorocebus aethiops; Fabaceae; Inhibitory Concentration 50; Leishmania donovani; Macrophages; Plants, Medicinal; Trypanosoma brucei brucei; Vero Cells

2005
Isoflavonoids and other compounds from Psorothamnus arborescens with antiprotozoal activities.
    Journal of natural products, 2006, Volume: 69, Issue:1

    Topics: Animals; Antiprotozoal Agents; California; Chlorocebus aethiops; Fabaceae; Genistein; Inhibitory Concentration 50; Isoflavones; Leishmania donovani; Molecular Structure; Plant Roots; Plants, Medicinal; Trypanosoma brucei brucei; Vero Cells

2006
Synthesis, biological evaluation, and molecular modeling of 3,5-substituted-N1-phenyl-N4,N4-di-n-butylsulfanilamides as antikinetoplastid antimicrotubule agents.
    Bioorganic & medicinal chemistry, 2007, Sep-15, Volume: 15, Issue:18

    Topics: Animals; Cell Line; Kinetoplastida; Leishmania donovani; Microtubules; Models, Chemical; Models, Molecular; Structure-Activity Relationship; Sulfanilamides; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Tubulin Modulators

2007
Trypanocidal and antileishmanial dihydrochelerythrine derivatives from Garcinia lucida.
    Journal of natural products, 2007, Volume: 70, Issue:10

    Topics: Animals; Antiprotozoal Agents; Benzophenanthridines; Cameroon; Chlorocebus aethiops; Garcinia; Leishmania donovani; Molecular Structure; Phenanthrenes; Plants, Medicinal; Trypanosoma brucei brucei; Vero Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
New lycorine-type alkaloid from Lycoris traubii and evaluation of antitrypanosomal and antimalarial activities of lycorine derivatives.
    Bioorganic & medicinal chemistry, 2008, Dec-15, Volume: 16, Issue:24

    Topics: Alkaloids; Amaryllidaceae Alkaloids; Animals; Antimalarials; Inhibitory Concentration 50; Liliaceae; Parasitic Sensitivity Tests; Phenanthridines; Plasmodium falciparum; Trypanocidal Agents

2008
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences.
    Journal of medicinal chemistry, 2009, Sep-24, Volume: 52, Issue:18

    Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Cathepsin L; Cathepsins; Cattle; Combinatorial Chemistry Techniques; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diamide; Drug Evaluation, Preclinical; Fumarates; Humans; Peptide Library; Plasmodium falciparum

2009
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids.
    Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5

    Topics: Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2010
Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: Effect of core substitutions and salt formation.
    Bioorganic & medicinal chemistry, 2011, Jan-01, Volume: 19, Issue:1

    Topics: Animals; Cyclization; Mice; Quinolines; Salts; Structure-Activity Relationship; Trypanocidal Agents

2011
Design, synthesis, and structure-activity relationship of Trypanosoma brucei leucyl-tRNA synthetase inhibitors as antitrypanosomal agents.
    Journal of medicinal chemistry, 2011, Mar-10, Volume: 54, Issue:5

    Topics: Animals; Boronic Acids; Cell Line; Drug Design; Leucine-tRNA Ligase; Mice; Models, Molecular; Stereoisomerism; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2011
Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei.
    Journal of natural products, 2013, Apr-26, Volume: 76, Issue:4

    Topics: Animals; Biological Products; Chagas Disease; Glycolysis; Humans; Leishmania donovani; Lipopeptides; Microbodies; Microscopy, Fluorescence; Trypanosoma brucei brucei; Zebrafish

2013
Semisynthesis of salviandulin E analogues and their antitrypanosomal activity.
    Bioorganic & medicinal chemistry letters, 2014, Jan-15, Volume: 24, Issue:2

    Topics: Crystallography, X-Ray; Humans; Plant Extracts; Salvia; Trypanocidal Agents; Trypanosoma brucei brucei

2014
Novel pyrrolobenzoxaboroles: design, synthesis, and biological evaluation against Trypanosoma brucei.
    European journal of medicinal chemistry, 2014, Jun-23, Volume: 81

    Topics: Animals; Boron Compounds; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Female; Mice; Mice, Inbred BALB C; Molecular Structure; Parasitic Sensitivity Tests; Pyrroles; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2014
Characterization of 2,4-Diamino-6-oxo-1,6-dihydropyrimidin-5-yl Ureido Based Inhibitors of Trypanosoma brucei FolD and Testing for Antiparasitic Activity.
    Journal of medicinal chemistry, 2015, Oct-22, Volume: 58, Issue:20

    Topics: Animals; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Humans; Leukemia; Macrophages; Methylenetetrahydrofolate Dehydrogenase (NADP); Models, Molecular; Phenylurea Compounds; Pyrimidinones; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2015
Chemotherapy of sleeping sickness.
    The Central African journal of medicine, 1979, Volume: 25, Issue:11

    Topics: Arsenicals; Humans; Melarsoprol; Pentamidine; Suramin; Trypanosomiasis, African

1979
The experimental chemotherapy of leishmaniasis. II. The activity in tissue culture of some antiparasitic and antimicrobial compounds in clinical use.
    Annals of tropical medicine and parasitology, 1975, Volume: 69, Issue:3

    Topics: Aminoquinolines; Animals; Anti-Bacterial Agents; Antimalarials; Antimony; Antiprotozoal Agents; Ascitic Fluid; Cell Line; Chloroquine; Cricetinae; Culture Techniques; Dogs; Drug Evaluation, Preclinical; Folic Acid Antagonists; Leishmania; Niridazole; Pentamidine; Primaquine; Quinacrine; Quinine; Sarcoma; Sulfonamides; Sulfones; Suramin

1975
Tryparsamide.
    Lancet (London, England), 1989, Sep-02, Volume: 2, Issue:8662

    Topics: Drug Therapy, Combination; Humans; Melarsoprol; Nigeria; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African

1989
In vitro drug sensitivity test for Trypanosoma brucei subgroup bloodstream trypomastigotes.
    Acta tropica, 1989, Volume: 46, Issue:5-6

    Topics: Animals; Arsenicals; Diminazene; Hypoxanthine; Hypoxanthines; Leucine; Pentamidine; Phenanthridines; Suramin; Thymidine; Trypanocidal Agents; Trypanosoma brucei brucei

1989
In vitro drug sensitivity of Trypanosoma gambiense isolates.
    Acta tropica, 1989, Volume: 46, Issue:5-6

    Topics: Animals; Arsenicals; Cote d'Ivoire; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

1989
Inhibition of leishmanial protein kinase by antileishmanial drugs.
    The American journal of tropical medicine and hygiene, 1988, Volume: 38, Issue:2

    Topics: Adenosine Triphosphate; Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Deoxyadenosines; Formycins; Leishmania mexicana; Pentamidine; Protein Kinase Inhibitors; Protein Kinases; Ribonucleotides; Suramin

1988
The effect of trypanocidal drugs on the transmission of Trypanosoma brucei brucei by Glossina morsitans centralis.
    Acta tropica, 1987, Volume: 44, Issue:1

    Topics: Animals; Diminazene; Pentamidine; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Tsetse Flies

1987
Drugs for protozoan infections.
    American family physician, 1987, Volume: 35, Issue:3

    Topics: Antimalarials; Antimony Sodium Gluconate; Antiprotozoal Agents; Humans; Iodoquinol; Melarsoprol; Metronidazole; Nifurtimox; Pentamidine; Protozoan Infections; Suramin

1987
Flow cytofluorimetric analysis of drug accumulation by multidrug-resistant Trypanosoma brucei brucei and T. b. rhodesiense.
    Molecular and biochemical parasitology, 1987, Volume: 26, Issue:1-2

    Topics: Acriflavine; Animals; Benzimidazoles; Diminazene; Drug Resistance; Ethidium; Flow Cytometry; Fluorescent Dyes; Humans; Indoles; Melarsoprol; Mice; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei

1987
Drug sensitivity of pleomorphic Trypanosoma rhodesiense.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1983, Volume: 77, Issue:2

    Topics: Animals; Arsenicals; Drug Resistance, Microbial; Ethidium; Mice; Pentamidine; Quinolinium Compounds; Suramin; Trypanocidal Agents; Trypanosomiasis, African

1983
Arsenic and old taxa: subspeciation and drug sensitivity in Trypanosoma brucei.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1984, Volume: 78, Issue:6

    Topics: Animals; Arsenicals; Diminazene; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Isoenzymes; Male; Melarsoprol; Mice; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1984
[Current therapy of trypanosomiasis].
    Bulletin de la Societe de pathologie exotique (1990), 1994, Volume: 87, Issue:5

    Topics: Adenosylmethionine Decarboxylase; Animals; Arsenicals; Deoxyadenosines; Drug Resistance; Eflornithine; Enzyme Inhibitors; Hospitalization; Humans; Melarsoprol; Pentamidine; Randomized Controlled Trials as Topic; Recurrence; Suramin; Triazines; Trypanocidal Agents; Trypanosomiasis, African

1994
A trypanosome oligopeptidase as a target for the trypanocidal agents pentamidine, diminazene and suramin.
    FEBS letters, 1998, Aug-21, Volume: 433, Issue:3

    Topics: Animals; Diminazene; Pentamidine; Serine Endopeptidases; Serine Proteinase Inhibitors; Structure-Activity Relationship; Suramin; Trypanocidal Agents; Trypanosoma

1998
Anti-sleeping sickness drugs and cancer chemotherapy.
    Parasitology today (Personal ed.), 2000, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents; Eflornithine; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2000
Treatment of human African trypanosomiasis.
    Bulletin of the World Health Organization, 2000, Volume: 78, Issue:12

    Topics: Acetanilides; Africa; Humans; Melarsoprol; Nitroimidazoles; Pentamidine; Suramin; Thiadiazoles; Trypanocidal Agents; Trypanosomiasis, African

2000
Availability and affordability of treatment for Human African Trypanosomiasis.
    Tropical medicine & international health : TM & IH, 2001, Volume: 6, Issue:11

    Topics: Eflornithine; Health Services Accessibility; Humans; Melarsoprol; Pentamidine; Research; Suramin; Trypanocidal Agents; Trypanosomiasis, African; World Health Organization

2001
[The return of sleeping sickness in an epidemic form: international action for drugs].
    Nederlands tijdschrift voor geneeskunde, 2002, Dec-28, Volume: 146, Issue:52

    Topics: Africa, Central; Animals; Disease Outbreaks; Eflornithine; Humans; International Cooperation; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

2002
[Study of the suramin pentamidine salt].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1954, Volume: 148, Issue:1-2

    Topics: Pentamidine; Sodium Chloride; Sodium Chloride, Dietary; Suramin; Trypanosomiasis

1954
[Study of the experimental trypanocide action of suramin and pentamidine and a suramin/pentamidine salt; trial of chemophrophylaxis on T. brucei Pasteur strain; preliminary note].
    Bulletin de la Societe de pathologie exotique et de ses filiales, 1954, Volume: 47, Issue:2

    Topics: Animals; Pentamidine; Sodium Chloride; Suramin; Trypanocidal Agents; Trypanosoma

1954
[Preliminary note on combined lomidine and moranyl in the prevention of sleeping sickness].
    Bulletin de la Societe de pathologie exotique et de ses filiales, 1955, Volume: 48, Issue:1

    Topics: Amidines; Animals; Biomedical Research; Humans; Pentamidine; Suramin; Trypanosomiasis; Trypanosomiasis, African; Urea

1955
[Chemotherapy and chemoprophylaxis of sleeping sickness caused by Trypanosoma gambiense].
    Revue medicale de Liege, 1959, Jan-01, Volume: 14, Issue:1

    Topics: Animals; Arsenicals; Chemoprevention; Humans; Pentamidine; Suramin; Trypanosoma brucei gambiense; Trypanosomiasis; Trypanosomiasis, African

1959
The trypanocidal action of homidium, quinapyramine and suramin.
    British journal of pharmacology and chemotherapy, 1960, Volume: 15

    Topics: Animals; Arsenicals; Ethidium; Mice; Pentamidine; Quinolines; Quinolinium Compounds; Suramin; Trypanocidal Agents; Trypanosomiasis

1960
Drug resistance in trapanososmes: cross-resitance analyses.
    British journal of pharmacology and chemotherapy, 1959, Volume: 14

    Topics: Aminoquinolines; Arsenicals; Drug Resistance; Humans; Pentamidine; Phenanthridines; Stilbamidines; Suramin; Trypanosoma; Trypanosoma brucei rhodesiense

1959
Bloodstream form-specific up-regulation of silent vsg expression sites and procyclin in Trypanosoma brucei after inhibition of DNA synthesis or DNA damage.
    The Journal of biological chemistry, 2004, Apr-02, Volume: 279, Issue:14

    Topics: Animals; Antiprotozoal Agents; Aphidicolin; Blood; Diminazene; DNA Damage; Enzyme Inhibitors; Gene Silencing; Genes, Reporter; Green Fluorescent Proteins; Luminescent Proteins; Membrane Glycoproteins; Pentamidine; Protozoan Proteins; RNA Polymerase I; S Phase; Suramin; Transcription, Genetic; Trypanocidal Agents; Trypanosoma brucei brucei; Up-Regulation; Variant Surface Glycoproteins, Trypanosoma

2004
The inhibition of some pharmacological actions of pentamidine by suramin.
    British journal of pharmacology and chemotherapy, 1951, Volume: 6, Issue:3

    Topics: Humans; Pentamidine; Suramin

1951
A woman with fever and rash after African safari.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Sep-01, Volume: 43, Issue:5

    Topics: Africa; Exanthema; Female; Fever; Humans; Melarsoprol; Middle Aged; Pentamidine; Suramin; Travel; Trypanocidal Agents; Trypanosomiasis, African

2006
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3

    Topics: Adenine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Disease Models, Animal; Drug Interactions; Eflornithine; Indomethacin; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nifurtimox; Pentamidine; Perfusion; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African

2009
Human African trypanosomiasis.
    Lancet (London, England), 2010, Jan-09, Volume: 375, Issue:9709

    Topics: Africa; Animals; Biomedical Research; Communicable Disease Control; Eflornithine; Endemic Diseases; Humans; Incidence; Insect Bites and Stings; Insect Vectors; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African; Tsetse Flies; Variant Surface Glycoproteins, Trypanosoma

2010
East African trypanosomiasis in a pregnant traveler.
    Emerging infectious diseases, 2009, Volume: 15, Issue:11

    Topics: Adult; Communicable Diseases, Emerging; Female; Humans; Infant, Newborn; London; Pentamidine; Pregnancy; Pregnancy Complications, Parasitic; Suramin; Tanzania; Travel; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2009
Killer coma: the evolving story of sleeping sickness treatment.
    Lancet (London, England), 2010, Jan-09, Volume: 375, Issue:9709

    Topics: Animals; Biomedical Research; Drug Discovery; Drug Resistance; Drug Therapy, Combination; Eflornithine; Humans; Insect Vectors; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African; Tsetse Flies; World Health Organization

2010
In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi.
    Veterinary parasitology, 2010, May-11, Volume: 169, Issue:3-4

    Topics: Amidines; Animals; Arsenicals; Cells, Cultured; Diminazene; Drug Resistance; Female; Inhibitory Concentration 50; Mice; Pentamidine; Quinolinium Compounds; Rats; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis

2010
High-throughput decoding of antitrypanosomal drug efficacy and resistance.
    Nature, 2012, Jan-25, Volume: 482, Issue:7384

    Topics: Aquaglyceroporins; Drug Resistance; Eflornithine; Endocytosis; Glycosylation; High-Throughput Screening Assays; Humans; Lysosomes; Melarsoprol; Nifurtimox; Pentamidine; RNA Interference; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2012
A returning traveller with fever, facial swelling, and skin lesions.
    BMJ (Clinical research ed.), 2012, Mar-22, Volume: 344

    Topics: Adrenal Cortex Hormones; Animals; Diagnosis, Differential; Disease Progression; Face; Fever; Humans; Lethargy; Male; Middle Aged; Pentamidine; Skin; Suramin; Travel Medicine; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Tsetse Flies; Zambia

2012
Evaluation of trypanocidal drugs used for human African trypanosomosis against Trypanosoma lewisi.
    Parasite (Paris, France), 2013, Volume: 20

    Topics: Animals; Eflornithine; Female; Humans; Immunocompromised Host; Inhibitory Concentration 50; Melarsoprol; Mice; Nifurtimox; Nitroimidazoles; Parasitemia; Pentamidine; Rats; Rats, Wistar; Suramin; Trypanocidal Agents; Trypanosoma lewisi; Trypanosomiasis

2013
African sleeping sickness.
    British journal of hospital medicine (London, England : 2005), 2016, Volume: 77, Issue:10

    Topics: Animals; Eflornithine; Humans; Insect Vectors; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Tsetse Flies

2016
Human African Trypanosomiasis in a Spanish traveler returning from Tanzania.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:3

    Topics: Diagnosis, Differential; Female; Humans; Middle Aged; Pentamidine; Spain; Suramin; Tanzania; Travel; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2017
A case of delayed diagnosis of East-African trypanosomiasis in a Dutch traveller.
    Journal of travel medicine, 2018, 01-01, Volume: 25, Issue:1

    Topics: Animals; Delayed Diagnosis; Diagnosis, Differential; Female; Humans; Kenya; Malaria; Middle Aged; Netherlands; Pentamidine; Suramin; Tanzania; Travel; Trypanosoma; Trypanosomiasis, African

2018
Trypanosoma brucei rhodesiense infection in a Chinese traveler returning from the Serengeti National Park in Tanzania.
    Infectious diseases of poverty, 2018, May-21, Volume: 7, Issue:1

    Topics: Adult; China; Communicable Diseases, Imported; Female; Humans; Parks, Recreational; Pentamidine; Polymerase Chain Reaction; Suramin; Tanzania; Travel; Treatment Outcome; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2018
Insights into antitrypanosomal drug mode-of-action from cytology-based profiling.
    PLoS neglected tropical diseases, 2018, Volume: 12, Issue:11

    Topics: Cell Biology; Humans; Lysosomes; Melarsoprol; Mitochondria; Mitochondrial Proteins; Mitosis; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2018
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model.
    PloS one, 2020, Volume: 15, Issue:11

    Topics: Animals; Diminazene; Disease Models, Animal; Drug Resistance; Kenya; Male; Melarsoprol; Mice; Pentamidine; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda; Virulence

2020
Differences in Transporters Rather than Drug Targets Are the Principal Determinants of the Different Innate Sensitivities of
    International journal of molecular sciences, 2022, Mar-05, Volume: 23, Issue:5

    Topics: Animals; Arsenicals; Membrane Transport Proteins; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosoma congolense

2022