Page last updated: 2024-08-16

suramin and nifurtimox

suramin has been researched along with nifurtimox in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's3 (16.67)18.2507
2000's5 (27.78)29.6817
2010's8 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Figadère, B; Fournet, A; Franck, X; Hocquemiller, R; Mahieux, R; Prina, E1
Alvarez, DE; Boiani, L; Bollini, M; Bruno, AM; Casal, JJ; Cerecetto, H; González, M1
Büchold, C; Gelhaus, C; Gut, J; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Stempka, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Breuning, A; Büchold, C; Degel, B; Gelhaus, C; Gut, J; Heppner, S; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rath, J; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Schulz, F; Stempka, M; Stich, A1
Ariën, KK; Augustyns, K; Cos, P; Dirié, B; Heeres, J; Joossens, J; Lewi, PJ; Lyssens, S; Maes, L; Michiels, J; Van der Veken, P; Vanham, G; Venkatraj, M1
Jennings, FW1
Lefrock, JL; Smith, BR1
Gutteridge, WE1
Milord, F; Pépin, J1
Brun, R; Iten, M; Kaminsky, R; Matovu, E1
De Koning, HP; Dogruel, M; Rodgers, J; Sanderson, L; Thomas, SA1
Schlitzer, M1
Alsford, S; Baker, N; Berriman, M; Eckert, S; Field, MC; Glover, L; Horn, D; Leung, KF; Sanchez-Flores, A; Turner, DJ1
Bucheton, B; Courtois, P; Cuny, G; Daulouède, S; Dethoua, M; Nzoumbou-Boko, R; Semballa, S; Truc, P; Vincendeau, P1
Chiodini, PL; Fink, D; Hedley, L; Sparkes, D1
Alsford, S; Baker, N; Dominicus, C; Glover, L; Horn, D; Hutchinson, S; Thomas, JA; Trenaman, A1

Reviews

3 review(s) available for suramin and nifurtimox

ArticleYear
Existing chemotherapy and its limitations.
    British medical bulletin, 1985, Volume: 41, Issue:2

    Topics: Chagas Disease; Gentian Violet; Humans; Melarsoprol; Nifurtimox; Nitroimidazoles; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African

1985
The treatment of human African trypanosomiasis.
    Advances in parasitology, 1994, Volume: 33

    Topics: Animals; Diminazene; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

1994
[Agents for the treatment of African sleeping sickness. Those developed in the last century].
    Pharmazie in unserer Zeit, 2009, Volume: 38, Issue:6

    Topics: Animals; Eflornithine; History, 20th Century; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African

2009

Other Studies

15 other study(ies) available for suramin and nifurtimox

ArticleYear
Biological evaluation of substituted quinolines.
    Bioorganic & medicinal chemistry letters, 2004, Jul-16, Volume: 14, Issue:14

    Topics: Animals; Antiparasitic Agents; Cell Line; Cell Transformation, Viral; Evaluation Studies as Topic; HTLV-I Infections; Leishmania; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Trypanosoma

2004
New potent imidazoisoquinolinone derivatives as anti-Trypanosoma cruzi agents: biological evaluation and structure-activity relationships.
    Bioorganic & medicinal chemistry, 2009, Feb-15, Volume: 17, Issue:4

    Topics: Animals; Chagas Disease; DNA, Protozoan; Dose-Response Relationship, Drug; Glutathione; HeLa Cells; Humans; Imidazoles; Isoquinolines; Models, Molecular; Oxidation-Reduction; Quantitative Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi

2009
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences.
    Journal of medicinal chemistry, 2009, Sep-24, Volume: 52, Issue:18

    Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Cathepsin L; Cathepsins; Cattle; Combinatorial Chemistry Techniques; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diamide; Drug Evaluation, Preclinical; Fumarates; Humans; Peptide Library; Plasmodium falciparum

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids.
    Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5

    Topics: Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2010
From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.
    Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19

    Topics: Anti-HIV Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense

2014
Chemotherapy of CNS-trypanosomiasis: the combined use of the arsenicals and nitro-compounds.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1991, Volume: 42, Issue:2

    Topics: Animals; Antiprotozoal Agents; Arsenicals; Brain Diseases; Drug Synergism; Drug Therapy, Combination; Female; Ketoconazole; Metronidazole; Mice; Nifurtimox; Nitro Compounds; Nitroimidazoles; Oxidation-Reduction; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1991
Drugs for protozoan infections.
    American family physician, 1987, Volume: 35, Issue:3

    Topics: Antimalarials; Antimony Sodium Gluconate; Antiprotozoal Agents; Humans; Iodoquinol; Melarsoprol; Metronidazole; Nifurtimox; Pentamidine; Protozoan Infections; Suramin

1987
Innate lack of susceptibility of Ugandan Trypanosoma brucei rhodesiense to DL-alpha-difluoromethylornithine (DFMO).
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1995, Volume: 46, Issue:3

    Topics: Animals; Drug Resistance; Eflornithine; Female; Humans; Hypoxanthine; Hypoxanthines; Melarsoprol; Mice; Mice, Inbred ICR; Nifurtimox; Species Specificity; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda

1995
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3

    Topics: Adenine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Disease Models, Animal; Drug Interactions; Eflornithine; Indomethacin; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nifurtimox; Pentamidine; Perfusion; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African

2009
Killer coma: the evolving story of sleeping sickness treatment.
    Lancet (London, England), 2010, Jan-09, Volume: 375, Issue:9709

    Topics: Animals; Biomedical Research; Drug Discovery; Drug Resistance; Drug Therapy, Combination; Eflornithine; Humans; Insect Vectors; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African; Tsetse Flies; World Health Organization

2010
High-throughput decoding of antitrypanosomal drug efficacy and resistance.
    Nature, 2012, Jan-25, Volume: 482, Issue:7384

    Topics: Aquaglyceroporins; Drug Resistance; Eflornithine; Endocytosis; Glycosylation; High-Throughput Screening Assays; Humans; Lysosomes; Melarsoprol; Nifurtimox; Pentamidine; RNA Interference; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2012
Evaluation of trypanocidal drugs used for human African trypanosomosis against Trypanosoma lewisi.
    Parasite (Paris, France), 2013, Volume: 20

    Topics: Animals; Eflornithine; Female; Humans; Immunocompromised Host; Inhibitory Concentration 50; Melarsoprol; Mice; Nifurtimox; Nitroimidazoles; Parasitemia; Pentamidine; Rats; Rats, Wistar; Suramin; Trypanocidal Agents; Trypanosoma lewisi; Trypanosomiasis

2013
African sleeping sickness.
    British journal of hospital medicine (London, England : 2005), 2016, Volume: 77, Issue:10

    Topics: Animals; Eflornithine; Humans; Insect Vectors; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Tsetse Flies

2016
Insights into antitrypanosomal drug mode-of-action from cytology-based profiling.
    PLoS neglected tropical diseases, 2018, Volume: 12, Issue:11

    Topics: Cell Biology; Humans; Lysosomes; Melarsoprol; Mitochondria; Mitochondrial Proteins; Mitosis; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2018