Page last updated: 2024-08-16

suramin and lysine

suramin has been researched along with lysine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's1 (7.69)18.2507
2000's6 (46.15)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Barber, DL; George, R; Schneider, WJ1
Buell, G; Collo, G; Lewis, C; North, RA; Surprenant, A1
Arni, RK; Arruda, EZ; Gava, LM; Gutierrez, JM; Melo, PA; Murakami, MT; Zela, SP1
Arni, RK; Arruda, EZ; Calil-Eliás, S; Gutiérrez, JM; Lomonte, B; Martinez, AB; Melo, PA; Murakami, MT; Tomaz, MA1
Broomhead, HE; Cao, L; Fountain, SJ; North, RA; Young, MT1
Broomhead, HE; North, RA; Sim, JA1
Lee, ML; Lu, HW; Min, MY; Shih, PY; Wu, YW; Yang, HW1
Madsen, AS; Olsen, CA1
Auld, DS; Blackburn, EA; Boxer, MB; Fothergill-Gilmore, LA; McNae, IW; Michels, PA; Morgan, HP; Nowicki, MW; Shen, M; Veith, H; Walkinshaw, MD; Walsh, MJ; Wear, MA1
Evans, RJ; Farmer, LK; Schmid, R1
Jakoncic, J; Li, J; Morohashi, K; Plotnikov, AN; Ren, C; Rodriguez, Y; Smith, SG; Stojanoff, V; Walsh, M; Zeng, L; Zhou, MM1
Galleano, I; Jung, M; Madsen, AS; Olsen, CA; Schiedel, M1

Other Studies

13 other study(ies) available for suramin and lysine

ArticleYear
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Characterization of the chicken oocyte receptor for low and very low density lipoproteins.
    The Journal of biological chemistry, 1987, Dec-15, Volume: 262, Issue:35

    Topics: Animals; Apolipoproteins B; Binding, Competitive; Cattle; Chickens; Edetic Acid; Glucosides; Humans; Lipoproteins, HDL; Lysine; Methylation; Molecular Weight; Oocytes; Pronase; Receptors, LDL; Solubility; Suramin

1987
An antagonist-insensitive P2X receptor expressed in epithelia and brain.
    The EMBO journal, 1996, Jan-02, Volume: 15, Issue:1

    Topics: Adenosine Triphosphate; Animals; Base Sequence; Brain; Cloning, Molecular; DNA, Complementary; Epithelium; Gene Expression; Lysine; Molecular Sequence Data; Oligonucleotides; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X4; RNA, Messenger; Salivary Glands; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Structure-Activity Relationship; Suramin

1996
Crystallization and preliminary X-ray diffraction analysis of suramin, a highly charged polysulfonated napthylurea, complexed with a myotoxic PLA2 from Bothrops asper venom.
    Biochimica et biophysica acta, 2004, Dec-01, Volume: 1703, Issue:1

    Topics: Animals; Bothrops; Crotalid Venoms; Crystallography, X-Ray; Group II Phospholipases A2; Lysine; Molecular Structure; Phospholipases A; Phospholipases A2; Suramin; Urea; X-Ray Diffraction

2004
Inhibition of myotoxic activity of Bothrops asper myotoxin II by the anti-trypanosomal drug suramin.
    Journal of molecular biology, 2005, Jul-15, Volume: 350, Issue:3

    Topics: Animals; Anions; Binding Sites; Bothrops; Calcium; Catalysis; Chromatography, Ion Exchange; Crystallization; Crystallography, X-Ray; Databases, Protein; Electrons; Group II Phospholipases A2; Heparin; Lysine; Magnetic Resonance Spectroscopy; Mice; Models, Chemical; Models, Molecular; Molecular Conformation; Muscles; Neurotoxins; Phospholipases A; Phospholipases A2; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Proteins; Reptilian Proteins; Suramin; Trypanocidal Agents

2005
Thr339-to-serine substitution in rat P2X2 receptor second transmembrane domain causes constitutive opening and indicates a gating role for Lys308.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Nov-21, Volume: 27, Issue:47

    Topics: Adenosine Triphosphate; Amino Acid Substitution; Animals; Binding Sites; Cell Line; Cell Membrane; Humans; Ion Channel Gating; Lysine; Mutagenesis; Protein Binding; Protein Structure, Tertiary; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Serine; Suramin; Threonine

2007
Ectodomain lysines and suramin block of P2X1 receptors.
    The Journal of biological chemistry, 2008, Oct-31, Volume: 283, Issue:44

    Topics: Amino Acid Sequence; Animals; Benzenesulfonates; Cell Line; Humans; Kidney; Lysine; Mice; Molecular Sequence Data; Muscle, Smooth; Patch-Clamp Techniques; Protein Structure, Tertiary; Receptors, Purinergic P2; Receptors, Purinergic P2X; Sequence Homology, Amino Acid; Suramin

2008
Neurokinin 1 receptor activates transient receptor potential-like currents in noradrenergic A7 neurons in rats.
    Molecular and cellular neurosciences, 2009, Volume: 42, Issue:1

    Topics: Animals; Animals, Newborn; Antineoplastic Agents; Dopamine beta-Hydroxylase; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Antagonists; Isoindoles; Lysine; Membrane Potentials; Neurokinin-1 Receptor Antagonists; Neurons; Neurotransmitter Agents; Norepinephrine; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P; Suramin; TRPC Cation Channels

2009
Substrates for efficient fluorometric screening employing the NAD-dependent sirtuin 5 lysine deacylase (KDAC) enzyme.
    Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11

    Topics: Benzamides; Coumarins; Enzyme Assays; Fluorometry; Furans; Humans; Isoenzymes; Kinetics; Lysine; Naphthols; Protein Processing, Post-Translational; Quinolines; Recombinant Proteins; Sirtuins; Structure-Activity Relationship; Substrate Specificity; Succinates; Suramin

2012
A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase.
    The Biochemical journal, 2012, Nov-15, Volume: 448, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arginine; Benzoates; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Isoenzymes; Leishmania mexicana; Lysine; Models, Molecular; Protein Binding; Protein Conformation; Pyruvate Kinase; Recombinant Proteins; Saccharin; Species Specificity; Structure-Activity Relationship; Suramin

2012
Use of chimeras, point mutants, and molecular modeling to map the antagonist-binding site of 4,4',4″,4‴-(carbonylbis-(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakisbenzene-1,3-disulfonic acid (NF449) at P2X1 receptors for ATP.
    The Journal of biological chemistry, 2015, Jan-16, Volume: 290, Issue:3

    Topics: Adenosine Triphosphate; Animals; Benzenesulfonates; Binding Sites; Cysteine; Drug Design; Humans; Ligands; Lysine; Mice; Models, Molecular; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Oocytes; Point Mutation; Protein Binding; Purinergic P2X Receptor Antagonists; Rats; Suramin; Xenopus laevis

2015
Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.
    Chemistry & biology, 2015, Feb-19, Volume: 22, Issue:2

    Topics: Binding Sites; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Fluorescein-5-isothiocyanate; Histones; Humans; Lysine; Methylation; Polycomb Repressive Complex 1; Protein Binding; Protein Structure, Tertiary; Small Molecule Libraries; Static Electricity; Suramin

2015
A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation.
    Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3

    Topics: Acetamides; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorescent Dyes; Humans; Lysine; Models, Molecular; Molecular Structure; Sirtuin 2; Structure-Activity Relationship; Substrate Specificity; Suramin; Thiazoles

2016