Page last updated: 2024-08-16

suramin and eflornithine

suramin has been researched along with eflornithine in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (21.05)	18.7374
1990's	9 (23.68)	18.2507
2000's	10 (26.32)	29.6817
2010's	11 (28.95)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Glaser, M; Goebel, T; Hauber, I; Hauber, J; Heller, E; Hoerauf, A; Holzgrabe, U; Kaiser, A; Kloeckner, J; Ponte-Sucre, A; Projahn, H; Sarite, SR; Specht, S; Ulmer, D	1
Ishiyama, A; Kinoshita, E; Kitajima, M; Kogure, N; Omura, S; Otoguro, K; Takayama, H; Toriizuka, Y; Yamada, H	1
Büchold, C; Gelhaus, C; Gut, J; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Stempka, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Breuning, A; Büchold, C; Degel, B; Gelhaus, C; Gut, J; Heppner, S; Kisker, C; Leippe, M; Leyh, M; Machon, U; Rath, J; Rosenthal, PJ; Schirmeister, T; Schmuck, C; Schulz, F; Stempka, M; Stich, A	1
Clayton, C; De Muylder, G; Gerwick, L; Helbig, C; Knudsen, GM; Linington, RG; Mackey, ZB; Mascuch, SM; McKerrow, JH; Sanchez, LM	1
Aoyagi, Y; Fujiwara, K; Fukaya, H; Hitotsuyanagi, Y; Ishiyama, A; Iwatsuki, M; Ōmura, S; Otoguro, K; Sugawara, N; Takeya, K; Yamada, H; Yamazaki, A; Yano, R	1
Kaminsky, R; Zweygarth, E	1
Demey, F	1
Ormerod, WE; Raseroka, BH	1
Bales, JD; Harrison, SM; Mbwabi, DL; Schecter, PJ	1
Bacchi, CJ; Bienen, EJ; Bitonti, AJ; Clarkson, AB; McCann, PP; Nathan, HC; Sjoerdsma, A	1
Cerami, A; Jennings, FW; Ulrich, P	1
Clarkson, AB; Rosenberg, C; Williams, DE	1
Bouteille, B; Darde, ML; Pestre-Alexandre, M	1
Bacchi, CJ; Bienen, EJ; Clarkson, AB; Hutner, SH; McCann, PP; Nathan, HC; Sjoerdsma, A	1
Boa Yapo, F; Doua, F	1
Roberts, JF; Yunmbam, MK	1
Burudi, EM; Githiori, JB; Karanja, SM; Ndung'u, JM; Njue, AI	1
Kaminsky, R; Moloo, SK; Zweygarth, E	1
Milord, F; Pépin, J	1
Bacchi, CJ; Clarkson, AB; Goldberg, B; McCann, PP; Nathan, HC; Saric, M; Sjoerdsma, A; Yarlett, N	1
Brun, R; Iten, M; Kaminsky, R; Matovu, E	1
Chakrabarty, S; Rajagopal, S; Reynolds, S	1
Barrett, MP; Barrett, SV	1
de Koning, HP	1
Etchegorry, MG; Helenport, JP; Jannin, J; Legros, D; Pecoul, B	1
Kager, PA	1
Docampo, R; Moreno, SN	1
De Koning, HP; Dogruel, M; Rodgers, J; Sanderson, L; Thomas, SA	1
Blum, J; Brun, R; Burri, C; Chappuis, F	1
Schlitzer, M	1
Asakawa, Y; Hashimoto, T; Ishiyama, A; Iwatsuki, M; Kiyohara, H; Namatame, M; Nishihara-Tukashima, A; Omura, S; Otoguro, K; Yamada, H	1
Alsford, S; Baker, N; Berriman, M; Eckert, S; Field, MC; Glover, L; Horn, D; Leung, KF; Sanchez-Flores, A; Turner, DJ	1
Bucheton, B; Courtois, P; Cuny, G; Daulouède, S; Dethoua, M; Nzoumbou-Boko, R; Semballa, S; Truc, P; Vincendeau, P	1
Chiodini, PL; Fink, D; Hedley, L; Sparkes, D	1
Kolosevska, K; Sánchez-Moreno, M; Steverding, D	1

Reviews

4 review(s) available for suramin and eflornithine

Article	Year
The treatment of human African trypanosomiasis. Advances in parasitology, 1994, Volume: 33 Topics: Animals; Diminazene; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	1994
Transporters in African trypanosomes: role in drug action and resistance. International journal for parasitology, 2001, May-01, Volume: 31, Issue:5-6 Topics: Africa South of the Sahara; Animals; Arsenicals; Biological Transport; Eflornithine; Humans; Nitroimidazoles; Pentamidine; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African	2001
Current chemotherapy of human African trypanosomiasis. Parasitology research, 2003, Volume: 90 Supp 1 Topics: Animals; Eflornithine; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African	2003
[Agents for the treatment of African sleeping sickness. Those developed in the last century]. Pharmazie in unserer Zeit, 2009, Volume: 38, Issue:6 Topics: Animals; Eflornithine; History, 20th Century; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosomiasis, African	2009

Other Studies

34 other study(ies) available for suramin and eflornithine

Article	Year
In search of novel agents for therapy of tropical diseases and human immunodeficiency virus. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Animals; Anti-Bacterial Agents; Anti-HIV Agents; Antimalarials; Cell Line; Ethers; HIV-1; Humans; Leishmania major; Macrophages; Mice; Mice, Inbred C57BL; Oximes; Piperidines; Plasmodium falciparum; Spiro Compounds; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Virus Replication	2008
New lycorine-type alkaloid from Lycoris traubii and evaluation of antitrypanosomal and antimalarial activities of lycorine derivatives. Bioorganic & medicinal chemistry, 2008, Dec-15, Volume: 16, Issue:24 Topics: Alkaloids; Amaryllidaceae Alkaloids; Animals; Antimalarials; Inhibitory Concentration 50; Liliaceae; Parasitic Sensitivity Tests; Phenanthridines; Plasmodium falciparum; Trypanocidal Agents	2008
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences. Journal of medicinal chemistry, 2009, Sep-24, Volume: 52, Issue:18 Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Cathepsin L; Cathepsins; Cattle; Combinatorial Chemistry Techniques; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diamide; Drug Evaluation, Preclinical; Fumarates; Humans; Peptide Library; Plasmodium falciparum	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids. Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5 Topics: Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei	2010
Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei. Journal of natural products, 2013, Apr-26, Volume: 76, Issue:4 Topics: Animals; Biological Products; Chagas Disease; Glycolysis; Humans; Leishmania donovani; Lipopeptides; Microbodies; Microscopy, Fluorescence; Trypanosoma brucei brucei; Zebrafish	2013
Semisynthesis of salviandulin E analogues and their antitrypanosomal activity. Bioorganic & medicinal chemistry letters, 2014, Jan-15, Volume: 24, Issue:2 Topics: Crystallography, X-Ray; Humans; Plant Extracts; Salvia; Trypanocidal Agents; Trypanosoma brucei brucei	2014
Evaluation of DL-alpha-difluoromethylornithine against susceptible and drug-resistant Trypanosoma brucei brucei. Acta tropica, 1991, Volume: 48, Issue:3 Topics: Animals; Arsenicals; Culture Media; Diminazene; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Humans; Immune Sera; Male; Mice; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1991
Studies on the efficacy of DL-alpha-difluoromethylornithine (DFMO) associated with bleomycin and suramin for treatment of mice infected with metacyclic forms of Trypanosoma brucei brucei. Veterinary research communications, 1987, Volume: 11, Issue:3 Topics: Animals; Bleomycin; Drug Therapy, Combination; Eflornithine; Female; Mice; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African	1987
Screening compounds for sleeping sickness therapy without relapse. Bulletin de la Societe de pathologie exotique et de ses filiales, 1988, Volume: 81, Issue:3 Pt 2 Topics: Animals; Bleomycin; Drug Evaluation, Preclinical; Eflornithine; Melarsoprol; Metronidazole; Mice; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1988
Treatment of arsenical refractory Rhodesian sleeping sickness in Kenya. Annals of tropical medicine and parasitology, 1989, Volume: 83 Suppl 1 Topics: Adult; Animals; Arsenicals; Drug Therapy, Combination; Eflornithine; Female; Humans; Kenya; Male; Melarsoprol; Middle Aged; Recurrence; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African	1989
Effects of the ornithine decarboxylase inhibitors DL-alpha-difluoromethylornithine and alpha-monofluoromethyldehydroornithine methyl ester alone and in combination with suramin against Trypanosoma brucei brucei central nervous system models. The American journal of tropical medicine and hygiene, 1987, Volume: 36, Issue:1 Topics: Animals; Central Nervous System; Dose-Response Relationship, Drug; Drug Therapy, Combination; Eflornithine; Female; Mice; Ornithine Decarboxylase Inhibitors; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African	1987
Chemotherapy of trypanosomiasis: the use of guanylhydrazone compounds in the treatment of experimental murine trypanosomiasis. Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1987, Volume: 38, Issue:3 Topics: Animals; Drug Therapy, Combination; Eflornithine; Female; Mice; Mitoguazone; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African	1987
Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:8 Topics: Amphotericin B; Animals; Antiprotozoal Agents; Dapsone; Diminazene; Disease Models, Animal; Drug Combinations; Eflornithine; Female; Immunosuppression Therapy; Pneumonia, Pneumocystis; Random Allocation; Rats; Rats, Inbred Strains; Sulfamethoxazole; Suramin; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1988
[Action of drugs tested in an acellular medium and in mice infected with Trypanosoma brucei brucei]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1988, Volume: 81, Issue:3 Pt 2 Topics: Acetanilides; Animals; Culture Media; Cyclosporins; Eflornithine; In Vitro Techniques; Melarsoprol; Mice; Mitoguazone; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1988
New drug combination for experimental late-stage African trypanosomiasis: DL-alpha-difluoromethylornithine (DFMO) with suramin. The American journal of tropical medicine and hygiene, 1984, Volume: 33, Issue:6 Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Eflornithine; Humans; Injections, Intravenous; Mice; Ornithine; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African	1984
[Current therapy of trypanosomiasis]. Bulletin de la Societe de pathologie exotique (1990), 1994, Volume: 87, Issue:5 Topics: Adenosylmethionine Decarboxylase; Animals; Arsenicals; Deoxyadenosines; Drug Resistance; Eflornithine; Enzyme Inhibitors; Hospitalization; Humans; Melarsoprol; Pentamidine; Randomized Controlled Trials as Topic; Recurrence; Suramin; Triazines; Trypanocidal Agents; Trypanosomiasis, African	1994
In vivo evaluation of reuterin and its combinations with suramin, melarsoprol, DL-alpha-difluoromethylornithine and bleomycin in mice infected with Trypanosoma brucei brucei. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1993, Volume: 105, Issue:3 Topics: Aldehydes; Animals; Anti-Bacterial Agents; Bleomycin; Drug Therapy, Combination; Eflornithine; Female; Glyceraldehyde; Lethal Dose 50; Melarsoprol; Mice; Propane; Suramin; Trypanosomiasis, African	1993
Establishment of a partly DFMO-sensitive primate model of Trypanosoma rhodesiense sleeping sickness. Acta tropica, 1995, Volume: 59, Issue:1 Topics: Animals; Chlorocebus aethiops; Disease Models, Animal; Drug Therapy, Combination; Eflornithine; Suramin; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	1995
Trypanosoma simiae: in vitro studies on drug susceptibility. Acta tropica, 1993, Volume: 54, Issue:3-4 Topics: Animals; Arsenicals; Diminazene; Drug Resistance; Eflornithine; Parasitology; Quinolinium Compounds; Species Specificity; Suramin; Trypanocidal Agents; Trypanosoma	1993
Combination chemotherapy of drug-resistant Trypanosoma brucei rhodesiense infections in mice using DL-alpha-difluoromethylornithine and standard trypanocides. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:3 Topics: Animals; Arsenicals; Diminazene; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Eflornithine; Female; Mice; Suramin; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	1994
Innate lack of susceptibility of Ugandan Trypanosoma brucei rhodesiense to DL-alpha-difluoromethylornithine (DFMO). Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1995, Volume: 46, Issue:3 Topics: Animals; Drug Resistance; Eflornithine; Female; Humans; Hypoxanthine; Hypoxanthines; Melarsoprol; Mice; Mice, Inbred ICR; Nifurtimox; Species Specificity; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda	1995
Differentiation-inducing effect of retinoic acid, difluoromethylornithine, sodium butyrate and sodium suramin in human colon cancer cells. Cancer letters, 1998, Dec-11, Volume: 134, Issue:1 Topics: Antineoplastic Agents; Butyrates; Carcinoembryonic Antigen; Cell Differentiation; Cell Division; Colonic Neoplasms; Eflornithine; Fibronectins; HT29 Cells; Humans; Inhibitory Concentration 50; Suramin; Tretinoin; Tumor Cells, Cultured	1998
Anti-sleeping sickness drugs and cancer chemotherapy. Parasitology today (Personal ed.), 2000, Volume: 16, Issue:1 Topics: Animals; Antineoplastic Agents; Eflornithine; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2000
Availability and affordability of treatment for Human African Trypanosomiasis. Tropical medicine & international health : TM & IH, 2001, Volume: 6, Issue:11 Topics: Eflornithine; Health Services Accessibility; Humans; Melarsoprol; Pentamidine; Research; Suramin; Trypanocidal Agents; Trypanosomiasis, African; World Health Organization	2001
[The return of sleeping sickness in an epidemic form: international action for drugs]. Nederlands tijdschrift voor geneeskunde, 2002, Dec-28, Volume: 146, Issue:52 Topics: Africa, Central; Animals; Disease Outbreaks; Eflornithine; Humans; International Cooperation; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African	2002
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3 Topics: Adenine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Disease Models, Animal; Drug Interactions; Eflornithine; Indomethacin; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nifurtimox; Pentamidine; Perfusion; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African	2009
Human African trypanosomiasis. Lancet (London, England), 2010, Jan-09, Volume: 375, Issue:9709 Topics: Africa; Animals; Biomedical Research; Communicable Disease Control; Eflornithine; Endemic Diseases; Humans; Incidence; Insect Bites and Stings; Insect Vectors; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African; Tsetse Flies; Variant Surface Glycoproteins, Trypanosoma	2010
Killer coma: the evolving story of sleeping sickness treatment. Lancet (London, England), 2010, Jan-09, Volume: 375, Issue:9709 Topics: Animals; Biomedical Research; Drug Discovery; Drug Resistance; Drug Therapy, Combination; Eflornithine; Humans; Insect Vectors; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African; Tsetse Flies; World Health Organization	2010
In vitro antitrypanosomal activity of plant terpenes against Trypanosoma brucei. Phytochemistry, 2011, Volume: 72, Issue:16 Topics: Diterpenes; Eflornithine; Plants; Structure-Activity Relationship; Suramin; Terpenes; Trypanocidal Agents; Trypanosoma brucei brucei	2011
High-throughput decoding of antitrypanosomal drug efficacy and resistance. Nature, 2012, Jan-25, Volume: 482, Issue:7384 Topics: Aquaglyceroporins; Drug Resistance; Eflornithine; Endocytosis; Glycosylation; High-Throughput Screening Assays; Humans; Lysosomes; Melarsoprol; Nifurtimox; Pentamidine; RNA Interference; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2012
Evaluation of trypanocidal drugs used for human African trypanosomosis against Trypanosoma lewisi. Parasite (Paris, France), 2013, Volume: 20 Topics: Animals; Eflornithine; Female; Humans; Immunocompromised Host; Inhibitory Concentration 50; Melarsoprol; Mice; Nifurtimox; Nitroimidazoles; Parasitemia; Pentamidine; Rats; Rats, Wistar; Suramin; Trypanocidal Agents; Trypanosoma lewisi; Trypanosomiasis	2013
African sleeping sickness. British journal of hospital medicine (London, England : 2005), 2016, Volume: 77, Issue:10 Topics: Animals; Eflornithine; Humans; Insect Vectors; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Tsetse Flies	2016
Trypanocidal activity of tetradentated pyridine-based manganese complexes is not linked to inactivation of superoxide dismutase. Experimental parasitology, 2018, Volume: 192 Topics: Antioxidants; Drug Interactions; Eflornithine; HL-60 Cells; Humans; Manganese Compounds; Microbial Sensitivity Tests; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pyrogallol; Superoxide Dismutase; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2018