suramin has been researched along with alpha,beta-methyleneadenosine 5'-triphosphate in 161 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.24) | 18.7374 |
| 1990's | 92 (57.14) | 18.2507 |
| 2000's | 54 (33.54) | 29.6817 |
| 2010's | 12 (7.45) | 24.3611 |
| 2020's | 1 (0.62) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobson, KA; Jarvis, MF; Williams, M | 1 |
| Mallard, N; Marshall, R; Sithers, A; Spriggs, B | 1 |
| Muir, TC; Nally, JE | 1 |
| Colquhoun, D; Edwards, FA; Gibb, AJ | 1 |
| Späth, L; Starke, K; von Kügelgen, I | 1 |
| Reis, DJ; Sun, MK; Wahlestedt, C | 1 |
| Machaly, M; Sneddon, P | 1 |
| Bott, A; Eltze, M; Illes, P | 1 |
| Harms, L; Illes, P; Nörenberg, W; Tschöpl, M | 1 |
| Amerini, S; Ledda, F; Mantelli, L; Rubino, A | 1 |
| Furukawa, T; Katsuragi, T; Ogawa, S; Sato, C; Soejima, O; Tokunaga, T | 1 |
| Bültmann, R; Starke, K; von Kügelgen, I | 4 |
| Blakeley, AG; Brockbank, JE; Kelly, SS; Petersen, SA | 1 |
| Leff, P; O'Connor, SE; Wood, BE | 1 |
| Nickel, P; Schlicker, E; Urbanek, E | 1 |
| Burnstock, G; Hoyle, CH; Knight, GE | 1 |
| Göthert, M; Schlicker, E; Urbanek, E | 1 |
| Jiang, Q; Lau, WA; Pennefather, JN; Ventura, S | 1 |
| Fu, WM; Liou, JC | 1 |
| Hashimoto, M; Kokubun, S | 1 |
| Starke, K; Stoffel, D; von Kügelgen, I | 1 |
| Balcar, VJ; Bennett, MR; Killinger, S; Li, Y | 1 |
| Carvalho, F; Gonçalves, J; Queiroz, G; Vale, P | 1 |
| Akkermans, LM; Briejer, MR; Lefebvre, RA; Meulemans, AL; Schuurkes, JA | 1 |
| Humphrey, PP; Kennedy, I | 1 |
| Bültmann, R; Starke, K; Trendelenburg, M | 1 |
| Evans, RJ; Kennedy, C | 1 |
| Kigoshi, S; Muramatsu, I; Oda, Y | 1 |
| Krier, J; Venkova, K | 1 |
| Rump, LC; von Kügelgen, I | 1 |
| Bates, F; Donoso, MV; Huidobro-Toro, JP; Montiel, J | 1 |
| Barraco, RA; Dunbar, JC; Ergene, E; O'Leary, DS | 1 |
| Cipolla-Neto, J; Ferreira, ZS; Markus, RP | 1 |
| Bailey, SJ; Hourani, SM | 1 |
| Humphrey, PP; Kennedy, I; Trezise, DJ | 2 |
| Lacroix, JS; Potter, EK; Ulman, LG | 1 |
| Caparrotta, L; Chinellato, A; Fassina, G; Froldi, G; Pandolfo, L; Ragazzi, E | 1 |
| Bültmann, R; Starke, K | 3 |
| Besch, HR; Besch, KT; Bidasee, KR; Emmick, JT; Kwon, S | 1 |
| Fuder, H; Muth, U | 1 |
| Bao, JX; Stjärne, L | 1 |
| Kurz, K; Starke, K; von Kügelgen, I | 1 |
| Bjur, RA; Hashimoto, T; Hattori, K; Ishii, R; Shinozuka, K; Takeuchi, K; Westfall, DP | 1 |
| Amerini, S; Filippi, S; Ledda, F; Mantelli, L | 1 |
| Day, TA; Khanna, S; Sibbald, JR | 1 |
| Lupichuk, SM; Tabrizchi, R | 1 |
| Inoue, K; Koizumi, S; Nakazawa, K | 1 |
| Furukawa, T; Katsuragi, T; Usune, S | 1 |
| Barnard, EA; Burnstock, G; King, BF; Simon, J; Webb, TE | 1 |
| Nakamura, F; Strittmatter, SM | 1 |
| Burnstock, G; Rubino, A | 1 |
| Hollingsworth, M; Piper, AS | 1 |
| Bültmann, R; Kurz, G; Nickel, P; Pause, B; Starke, K; Wittenburg, H | 1 |
| Giachetti, A; Maggi, CA; Santicioli, P; Zagorodnyuk, V | 1 |
| Cook, AK; Inscho, EW; Navar, LG | 1 |
| Assmann, G; Beinlich, A; Heidenreich, S; Nofer, JR; Schlüter, H; Tepel, M; Walter, M; Zidek, W | 1 |
| Balcar, VJ; Bennett, MR; Coleman, MJ; Dampney, RA; Hansen, MA; Tuyau, M | 1 |
| Bianchi, L; Boselli, C; Grana, E | 1 |
| Burnstock, G; Ren, LM | 1 |
| Cazenave, JP; Gachet, C; Hechler, B; Léon, C; Leray, C; Vial, C | 1 |
| Iizuka, Y; Ishizaki, M; Kimura, T; Satoh, S; Suzuki-Kusaba, M | 1 |
| Ardanuy, U; Burnstock, G; Lambrecht, G; Mutschler, E; Nickel, P; Ziganshin, AU; Ziyal, R | 1 |
| Bowes, J; Kennedy, C; McIntyre, CA; Obeid, S; Sneddon, P; Westfall, TD | 1 |
| Hori, S; Kawamura, M | 1 |
| Reid, A; Sawynok, J | 1 |
| Barthó, L; Lénárd, L; Maggi, CA | 1 |
| Chiba, S; Haniuda, K; Nakane, T | 1 |
| Cheng, JT; Hung, YC; Kunitomo, M; Shinozuka, K; Tong, YC | 1 |
| Illes, P; Nieber, K; Poelchen, W | 1 |
| Abe, I; Fujii, K; Fujishima, M; Onaka, U | 1 |
| Chiba, S; Matsumoto, T; Nakane, T | 1 |
| Brodie, MJ; Ross, FM; Stone, TW | 1 |
| Buchanan, KJ; Burke, KS; Kennedy, C; McLaren, GJ; Sneddon, P | 1 |
| Babinski, K; Lê, KT; Séguéla, P | 1 |
| Chang, CC; Hong, SJ | 1 |
| Ito, S; Nakazato, Y; Ohta, T; Otsuguro, K | 1 |
| Konishi, C; Naito, Y; Ohara, N | 1 |
| Fleckenstein-Grün, G; Matyas, S; Seiler, L | 1 |
| Bültmann, R; Starke, K; Trendelenburg, M; Tuluc, F; Wittenburg, H | 1 |
| Gadd, CA; Ralevic, V; Spyer, KM; Thomas, T | 1 |
| Morris, JL | 1 |
| Dampney, RA; Horiuchi, J; Potts, PD; Tagawa, T | 1 |
| Cinkilic, O; Jankowski, J; Schlüter, H; Tepel, M; van der Giet, M; Zidek, W | 1 |
| Katsuragi, T; Sato, C; Tsujioka, Y | 1 |
| Barthó, L; Heinemann, A; Holzer, P; Shahbazian, A | 1 |
| Booth, CE; Chessell, IP; Grundy, D; Humphrey, PP; Kirkup, AJ | 1 |
| Eardley, I; Morrison, JF; Namasivayam, S | 1 |
| Matsuyama, H; Takewaki, T; Thapaliya, S | 1 |
| Nikbakht, MR; Stone, TW | 1 |
| Fukumitsu, A; Honda, K; Iki, A; Kamiya, H; Katsuragi, T; Saito, R; Takano, Y | 1 |
| Dowd, FJ; Li, LS; Zeng, W | 1 |
| Dickenson, AH; Kontinen, VK; Stanfa, LC | 1 |
| Barnard, EA; Chessell, IP; Humphrey, PP; Jones, CA; Michel, AD; Miller, KJ; Simon, J | 1 |
| Spyer, KM; Thomas, T | 1 |
| Burnstock, G; Rong, W; Spyer, KM | 1 |
| D'arbe, M; Lavidis, NA; Liang, SX; Phillips, WD | 1 |
| Kwan, CY; Shen, JZ; Zheng, XF | 1 |
| Ennion, SJ; Evans, RJ; Lewis, CJ | 1 |
| Carolan, BM; Harden, TK; Keef, KD; Mutafova-Yambolieva, VN | 1 |
| Burnstock, G; Gibb, AJ; Wong, AY | 1 |
| Dohi, T; Fukuhara, N; Imai, Y; Kitayama, S; Morita, K; Sakakibara, A; Tanne, K | 1 |
| O'Kane, EM; Stone, TW | 1 |
| Evans, RJ; Gitterman, DP | 1 |
| Evans, RJ; Lewis, CJ | 1 |
| Burnstock, G; Dunn, PM; Zhong, Y | 1 |
| Dacey, RG; Dietrich, HH; Horiuchi, T; Tsugane, S | 1 |
| Ralevic, V | 1 |
| Saino, T; Shinohe, Y | 1 |
| Burnstock, G; Rocha, I; Spyer, KM | 1 |
| Baumann, NL; Dahlstrom, PK; Gronau, RT; Light, DB | 1 |
| Coney, AM; Johnson, CD; Marshall, JM | 1 |
| Boselli, C; Govoni, S | 1 |
| Gourine, AV; Gourine, VN; Melenchuk, EV; Poputnikov, DM; Spyer, KM | 1 |
| Habara, Y; Takahashi-Iwanaga, H | 1 |
| Gurin, AV; Gurin, VN; Melenchuk, EV; Spyer, KM | 1 |
| Laube, B | 1 |
| Denda, M; Denda, S; Fuziwara, S; Inoue, K | 1 |
| Alessandro, M; Mulè, F; Serio, R; Tamburello, MP; Zizzo, MG | 1 |
| Dewalagama, RK; Lau, LC; Ventura, S | 1 |
| Kawa, K | 1 |
| De Man, JG; De Schepper, HU; De Winter, BY; Herman, AG; Pelckmans, PA; Seerden, TC | 1 |
| Rettinger, J; Schmalzing, G | 1 |
| Hori, S; Kawamura, M; Masaki, E; Yamazaki, K | 1 |
| Choi, SJ; Kim, JH; Kim, MH; Kim, SJ; Koh, DS; Lee, JE; Min, KM; Nam, JH; Uhm, DY | 1 |
| Ikomi, F; Kousai, A; Mizuno, R; Ohhashi, T | 1 |
| Buljubasich, R; Ventura, S | 1 |
| Acuna-Goycolea, C; van den Pol, AN; Wollmann, G | 1 |
| Almeida, T; Cunha, RA; Oliveira, CR; Richardson, PJ; Rodrigues, RJ | 1 |
| Büyüknacar, HS; Göçmen, C; Kumcu, EK; Onder, S; Singirik, E | 1 |
| Brock, JA; Yeoh, M | 1 |
| Brock, JA; McLachlan, EM; Yeoh, M | 1 |
| Hildebrandt, C; Horner, S; Kassack, MU; Lambrecht, G; Mahaut-Smith, MP; Menke, K; Nickel, P; Ullmann, H | 1 |
| Kinoshita, N; Mizuno, N; Shinozuka, K; Tada, S; Takahashi, K; Takahashi, T | 1 |
| Pinna, C; Puglisi, L; Sanvito, P | 1 |
| Aldrich, RW; Knorn, AM; Meredith, AL; Nelson, MT; Werner, ME | 1 |
| Aronsson, P; Eriksson, L; Giglio, D; Tobin, G | 1 |
| Lomax, AE; Neshat, S; O'Reilly, M; Vanner, SJ | 1 |
| Avelino-Cruz, JE; Berra-Romani, R; Moccia, F; Oldani, A; Raqeeb, A; Speroni, F; Taglietti, V; Tanzi, F | 1 |
| Baek, EB; Earm, YE; Kim, HS; Kim, SD; Kim, SJ; Park, SJ; Yoo, HY | 1 |
| Burnstock, G; Fan, J; Ma, B; Ni, X; Yu, LH | 1 |
| Boone, TB; Lai, HH; Munoz, A; Smith, CP; Somogyi, GT; Szigeti, GP | 1 |
| Kim, DR; Kong, ID; Lee, DH; Lee, JW; Park, KS | 1 |
| Andersson, M; Aronsson, P; Ericsson, T; Giglio, D | 1 |
| Chihara, Y; Ito, K; Iwasaki, S; Komuta, Y; Sahara, Y; Sugasawa, M | 1 |
| Gordienko, DV; Harhun, MI; Povstyan, OV | 1 |
| Ito, S; Lu, J; Matsumura, S; Naritsuka, H; Okuda-Ashitaka, E; Takagi, K; Yamaguchi, M | 1 |
| Huang, T; Jankowski, J; Jankowski, V; Klöckel, L; Schuchardt, M; Tölle, M; van der Giet, M; Wiedon, A; Zidek, W | 1 |
| Barbosa, SP; De Andrade, CA; De Paula, PM; Menani, JV; Menezes, MF | 1 |
| Schnermann, J | 1 |
| Amobi, NI; Guillebaud, J; Smith, IC | 1 |
| Burnstock, G; Crawford, C; Elliott, J; Fordham, AF; Janska, SE; Knight, GE; Peppiatt-Wildman, CM; Wildman, SS; Zerpa, H | 1 |
| Afeli, SA; Petkov, GV; Rovner, ES | 1 |
| Clavé, P; Gallego, D; Gil, V; Jiménez, M; Mañé, N; Martín, MT; Martínez-Cutillas, M | 1 |
| Alves, PM; Alves, RM; Conde, SV; Queiroga, CS; Vieira, HL | 1 |
| Fountain, SJ; Gonzalez-Montelongo, MDC | 1 |
1 review(s) available for suramin and alpha,beta-methyleneadenosine 5'-triphosphate
| Article | Year |
|---|---|
Purine and pyrimidine (P2) receptors as drug targets.
Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate | 2002 |
160 other study(ies) available for suramin and alpha,beta-methyleneadenosine 5'-triphosphate
| Article | Year |
|---|---|
Suramin: a selective inhibitor of purinergic neurotransmission in the rat isolated vas deferens.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Nifedipine; Norepinephrine; Purinergic Antagonists; Rats; Rats, Wistar; Suramin; Synaptic Transmission; Vas Deferens | 1992 |
The electrical and mechanical responses of the rabbit saphenous artery to nerve stimulation and drugs.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Arteries; Dioxanes; Electric Stimulation; Electrophysiology; Evoked Potentials; Idazoxan; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Junction; Norepinephrine; Phospholipids; Prazosin; Rabbits; Suramin; Sympathetic Nervous System | 1992 |
ATP receptor-mediated synaptic currents in the central nervous system.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Adenosine Triphosphate; Animals; Bicuculline; Brain; Chlorocebus aethiops; Evoked Potentials, Somatosensory; gamma-Aminobutyric Acid; Ganglionic Blockers; Glutamates; Glutamic Acid; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Ion Channels; Kynurenic Acid; Mecamylamine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Signal Transduction; Suramin; Tetrodotoxin | 1992 |
Stable adenine nucleotides inhibit [3H]-noradrenaline release in rabbit brain cortex slices by direct action at presynaptic adenosine A1-receptors.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Drug Interactions; Drug Stability; Electric Stimulation; Female; Male; Nerve Endings; Norepinephrine; Purinergic Antagonists; Rabbits; Receptors, Purinergic; Suramin; Synapses; Theophylline; Tritium; Xanthines | 1992 |
Action of externally applied ATP on rat reticulospinal vasomotor neurons.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Male; Medulla Oblongata; Neurons; Rats; Rats, Sprague-Dawley; Suramin; Vasomotor System | 1992 |
Regional variation in purinergic and adrenergic responses in isolated vas deferens of rat, rabbit and guinea-pig.
Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Epididymis; Guinea Pigs; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prostate; Rabbits; Rats; Receptors, Adrenergic; Receptors, Purinergic; Suramin; Vas Deferens | 1992 |
External ATP antagonizes the effect of potassium channel openers in guinea-pig ventricular papillary muscle.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Electric Stimulation; Glyburide; Guinea Pigs; Male; Myocardial Contraction; Papillary Muscles; Potassium Channels; Pyridines; Pyrroles; Suramin | 1992 |
Excitatory effects of adenosine 5'-triphosphate on rat locus coeruleus neurones.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Drug Interactions; Locus Coeruleus; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Purinergic; Suramin; Tetrodotoxin; Thionucleotides; Xanthines | 1992 |
ATP modulates the efferent function of capsaicin-sensitive neurones in guinea-pig isolated atria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Neurons, Efferent; Receptors, Purinergic; Suramin; Theophylline | 1992 |
Existence of ATP-evoked ATP release system in smooth muscles.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Firefly Luciferin; Guinea Pigs; Luciferases; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Receptors, Purinergic; Suramin; Vas Deferens | 1991 |
Contraction-mediating alpha 2-adrenoceptors in the mouse vas deferens.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dioxanes; Drug Interactions; Idazoxan; Male; Mice; Muscle Contraction; Neuropeptide Y; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Suramin; Vas Deferens; Yohimbine | 1991 |
Adrenergic and purinergic cotransmission in nicotine-evoked vasoconstriction in rabbit ileocolic arteries.
Topics: Adenosine Triphosphate; Animals; Arteries; Colon; Dose-Response Relationship, Drug; Female; Male; Nicotine; Norepinephrine; Prazosin; Rabbits; Receptors, Nicotinic; Suramin; Vasoconstriction | 1991 |
Effects of suramin on the concentration--response relationship of alpha, beta-methylene ATP on the mouse vas deferens.
Topics: Adenosine Triphosphate; Animals; Female; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Suramin; Triazines; Vas Deferens | 1991 |
Suramin is a slowly-equilibrating but competitive antagonist at P2x-receptors in the rabbit isolated ear artery.
Topics: Adenosine Triphosphate; Animals; Arteries; Binding, Competitive; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Receptors, Purinergic; Suramin | 1990 |
Interaction of adenine nucleotides, UTP and suramin in mouse vas deferens: suramin-sensitive and suramin-insensitive components in the contractile effect of ATP.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Norepinephrine; Suramin; Uridine Triphosphate; Vas Deferens | 1990 |
Antagonistic properties of four suramin-related compounds at vascular purine P2X receptors in the pithed rat.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Dose-Response Relationship, Drug; Male; Neuropeptide Y; Norepinephrine; Purinergic Antagonists; Rats; Rats, Inbred Strains; Suramin; Vasoconstrictor Agents | 1990 |
Suramin antagonizes responses to P2-purinoceptor agonists and purinergic nerve stimulation in the guinea-pig urinary bladder and taenia coli.
Topics: Adenosine Triphosphate; Animals; Atropine; Autonomic Nervous System; Carbachol; Colon; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle, Smooth; Neurons; Norepinephrine; Receptors, Purinergic; Suramin; Urinary Bladder | 1990 |
Effects of suramin and alpha, beta-methylene ATP indicate noradrenaline-ATP co-transmission in the response of the mouse vas deferens to single and low frequency pulses.
Topics: Adenosine Triphosphate; Animals; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Mice; Muscle, Smooth; Norepinephrine; Prazosin; Suramin; Synaptic Transmission; Vas Deferens; Yohimbine | 1989 |
ATP, alpha,beta-methylene ATP and suramin as tools for characterization of vascular P2x receptors in the pithed rat.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Decerebrate State; Electric Stimulation; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Suramin | 1989 |
Endothelin-induced facilitation of sympathetic neurotransmission to the rat vas deferens: effects of suramin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Endothelins; Epididymis; Glycopeptides; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Protease Inhibitors; Rats; Rats, Wistar; Receptors, Purinergic; Suramin; Sympathetic Nervous System; Synaptic Transmission; Vas Deferens | 1995 |
Additive effect of ADP and CGRP in modulation of the acetylcholine receptor channel in Xenopus embryonic myocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Heart; Myocardium; Patch-Clamp Techniques; Protein Kinase C; Receptors, Cholinergic; Receptors, Purinergic; Suramin; Tetradecanoylphorbol Acetate; Xenopus laevis | 1995 |
Contribution of P2-purinoceptors to neurogenic contraction of rat urinary bladder smooth muscle.
Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Atropine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Isotonic Contraction; Male; Muscle, Smooth; Parasympatholytics; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Thionucleotides; Triazines; Urinary Bladder | 1995 |
P2-purinoceptor-mediated inhibition of noradrenaline release in rat atria.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antihypertensive Agents; Atropine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; Indomethacin; Male; Norepinephrine; Phenethylamines; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Triazines; Xanthines; Yohimbine | 1995 |
Autoradiography of P2x ATP receptors in the rat brain.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Autoradiography; Binding, Competitive; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Dilazep; Female; Hippocampus; Ligands; Male; Ouabain; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Structure-Activity Relationship; Suramin; Thalamus; Thionucleotides | 1995 |
Electrically-evoked release of taurine in the rat vas deferens: evidence for a purinoceptor-mediated effect.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; In Vitro Techniques; Male; Norepinephrine; Prazosin; Rats; Rats, Wistar; Receptors, Purinergic; Reserpine; Suramin; Sympathetic Nervous System; Taurine; Tyramine; Vas Deferens | 1995 |
5-HT-induced neurogenic relaxations of the guinea-pig proximal colon: investigation into the role of ATP and VIP in addition to nitric oxide.
Topics: Adenosine Triphosphate; Animals; Apamin; Colon; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroglycerin; Serotonin; Suramin; Vasoactive Intestinal Peptide | 1995 |
Evidence for the presence of two types of P2 purinoceptor in the guinea-pig ileal longitudinal smooth muscle preparation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Atropine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Receptors, Purinergic P2; Suramin; Tetrodotoxin; Triazines; Uridine Triphosphate | 1994 |
Blockade of P2X-purinoceptors by trypan blue in rat vas deferens.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Potassium; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Suramin; Trypan Blue; Vas Deferens | 1994 |
Characterization of P2-purinoceptors in the smooth muscle of the rat tail artery: a comparison between contractile and electrophysiological responses.
Topics: Adenosine Triphosphate; Animals; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Tail; Thionucleotides; Uridine Triphosphate; Vasoconstriction | 1994 |
Evidence for sympathetic, purinergic transmission in the iris dilator muscle of the rabbit.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Female; Guanethidine; In Vitro Techniques; Iris; Male; Muscle Contraction; Neuropeptide Y; Prazosin; Rabbits; Receptors, Purinergic; Suramin; Tetrodotoxin; Thionucleotides | 1994 |
Stimulation of lumbar sympathetic nerves evokes contractions of cat colon circular muscle mediated by ATP and noradrenaline.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Azides; Cats; Colon; Electric Stimulation; Female; Lumbosacral Region; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Receptors, Purinergic P2; Suramin; Sympathetic Nervous System | 1993 |
A study of ATP as a sympathetic cotransmitter in human saphenous vein.
Topics: Action Potentials; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Electric Stimulation; Female; Guanethidine; Humans; In Vitro Techniques; Male; Middle Aged; Neuropeptide Y; Norepinephrine; Receptors, Purinergic; Saphenous Vein; Suramin; Synaptic Transmission; Tetrodotoxin; Vasoconstriction | 1994 |
Adenosine 5'-triphosphate (ATP), the neurotransmitter in the prostatic portion of the longitudinal muscle layer of the rat vas deferens.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Epididymis; In Vitro Techniques; Male; Muscle, Smooth; Neurotransmitter Agents; Norepinephrine; Prazosin; Prostate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Vas Deferens | 1994 |
Activation of P2-purinoceptors in the nucleus tractus solitarius mediate depressor responses.
Topics: Adenosine Triphosphate; Animals; Depression, Chemical; Hemodynamics; Injections, Intraventricular; Male; Microinjections; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Solitary Nucleus; Suramin; Thionucleotides | 1994 |
Presence of P2-purinoceptors in the rat pineal gland.
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Chromatography, High Pressure Liquid; Electrochemistry; Female; In Vitro Techniques; Male; Norepinephrine; Pineal Gland; Rats; Rats, Wistar; Receptors, Purinergic P2; Serotonin; Suramin | 1994 |
Differential effects of suramin on P2-purinoceptors mediating contraction of the guinea-pig vas deferens and urinary bladder.
Topics: Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Magnesium; Male; Muscle Contraction; Muscle, Smooth; Organ Specificity; Receptors, Purinergic P2; Suramin; Theophylline; Thionucleotides; Urinary Bladder; Vas Deferens | 1994 |
The use of antagonists to characterize the receptors mediating depolarization of the rat isolated vagus nerve by alpha, beta-methylene adenosine 5'-triphosphate.
Topics: Adenosine Triphosphate; Animals; Electrophysiology; In Vitro Techniques; Kinetics; Male; Neuromuscular Depolarizing Agents; Protein Synthesis Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Triazines; Vagus Nerve | 1994 |
The role of ATP in non-adrenergic sympathetic vascular control of the nasal mucosa in anaesthetized cats and dogs.
Topics: Adenosine Triphosphate; Adrenergic Antagonists; Anesthesia; Animals; Arteries; Blood Pressure; Cats; Dogs; Electric Stimulation; Female; Male; Nasal Mucosa; Norepinephrine; Regional Blood Flow; Suramin; Sympathetic Nervous System; Vascular Resistance; Vasoconstriction | 1994 |
Dual effect of ATP and UTP on rat atria: which types of receptors are involved?
Topics: Adenosine Deaminase; Adenosine Triphosphate; Animals; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Stimulation, Chemical; Suramin; Uridine Diphosphate; Xanthines | 1994 |
Blockade by 4,4'-diisothiocyanatostilbene-2,2'-disulphonate (DIDS) of P2X-purinoceptors in rat vas deferens.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle, Smooth; Norepinephrine; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Suramin; Vas Deferens | 1994 |
Evans blue blocks P2X-purinoceptors in rat vas deferens.
Topics: Adenosine Triphosphate; Animals; Evans Blue; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Potassium; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Suramin; Vas Deferens | 1993 |
Dual effect of suramin on calcium fluxes across sarcoplasmic reticulum vesicle membranes.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Calcium; Calcium Channels; Calcium-Transporting ATPases; Dithiothreitol; Drug Interactions; In Vitro Techniques; Rabbits; Ryanodine; Sarcoplasmic Reticulum; Suramin | 1994 |
ATP and endogenous agonists inhibit evoked [3H]-noradrenaline release in rat iris via A1 and P2y-like purinoceptors.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Adenosine Triphosphate; Animals; Electric Stimulation; In Vitro Techniques; Iris; Norepinephrine; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Synaptic Transmission; Triazines; Xanthines | 1993 |
Characterization of purinoceptors mediating depolarization of rat isolated vagus nerve.
Topics: Adenosine Triphosphate; Animals; Drug Synergism; Extracellular Space; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Neurons; Rats; Rats, Wistar; Receptors, Purinergic; Sensitivity and Specificity; Serotonin; Suramin; Vagus Nerve | 1993 |
Dual contractile effects of ATP released by field stimulation revealed by effects of alpha,beta-methylene ATP and suramin in rat tail artery.
Topics: Adenosine Triphosphate; Animals; Arteries; Electric Stimulation; In Vitro Techniques; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Tail; Tetraethylammonium Compounds; Vasoconstriction | 1993 |
Prejunctional modulation of noradrenaline release in mouse and rat vas deferens: contribution of P1- and P2-purinoceptors.
Topics: Adenosine Triphosphate; Animals; In Vitro Techniques; Male; Mice; Norepinephrine; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Vas Deferens; Xanthines | 1993 |
Purinergic facilitation of norepinephrine release from adrenergic nerves of rabbit ear artery.
Topics: 2-Chloroadenosine; Adenosine Triphosphate; Animals; Arteries; Ear, External; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Receptors, Purinergic; Regional Blood Flow; Suramin; Sympathetic Nervous System; Theophylline | 1993 |
Blockade of adenosine receptors unmasks a stimulatory effect of ATP on cardiac contractility.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Stimulation, Chemical; Suramin; Theophylline; Triazines; Xanthines | 1993 |
ATP mediates an excitatory noradrenergic neuron input to supraoptic vasopressin cells.
Topics: Adenosine Triphosphate; Animals; Male; Neurons; Norepinephrine; Purinergic Antagonists; Rats; Rats, Wistar; Supraoptic Nucleus; Suramin; Vagus Nerve; Vasopressins | 1993 |
Vasodilatation produced by adenosine in isolated rat perfused mesenteric artery: a role for endothelium.
Topics: Adenosine; Adenosine Triphosphate; Animals; Endothelium, Vascular; Glyburide; Male; Mesenteric Arteries; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Suramin; Theobromine; Theophylline; Vasodilation; Vasodilator Agents | 1995 |
Inhibition by Zn2+ of uridine 5'-triphosphate-induced Ca(2+)-influx but not Ca(2+)-mobilization in rat phaeochromocytoma cells.
Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Animals; Calcium; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Fura-2; Nicardipine; PC12 Cells; Pheochromocytoma; Rats; Receptors, Purinergic; Suramin; Thionucleotides; Uridine Triphosphate; Zinc | 1995 |
Effects of PPADS and suramin on contractions and cytoplasmic Ca2+ changes evoked by AP4A, ATP and alpha, beta-methylene ATP in guinea-pig urinary bladder.
Topics: Adenosine Triphosphate; Calcium; Calcium Channel Blockers; Cytoplasm; Dinucleoside Phosphates; In Vitro Techniques; Muscle Contraction; Nifedipine; Pyridoxal Phosphate; Suramin; Urinary Bladder | 1996 |
Characterisation of a recombinant P2Y purinoceptor.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Brain; Cell Line; Electrophysiology; Inositol Phosphates; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Recombinant Proteins; Suramin; Thionucleotides; Triazines; Uridine Triphosphate; Xenopus | 1995 |
P2Y1 purinergic receptors in sensory neurons: contribution to touch-induced impulse generation.
Topics: Adenosine Triphosphate; Animals; Apyrase; Chickens; Female; Ganglia, Spinal; Membrane Potentials; Molecular Sequence Data; Nerve Fibers; Neurons, Afferent; Oocytes; Physical Stimulation; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Receptors, Purinergic P2Y1; RNA, Messenger; Sciatic Nerve; Skin; Suramin; Time Factors; Transcription, Genetic; Xenopus laevis | 1996 |
Evidence for a P2-purinoceptor mediating vasoconstriction by UTP, ATP and related nucleotides in the isolated pulmonary vascular bed of the rat.
Topics: Adenosine Triphosphate; Animals; In Vitro Techniques; Male; Platelet Aggregation Inhibitors; Pulmonary Circulation; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Uridine Triphosphate; Vasoconstriction | 1996 |
ATP and beta,gamma-methylene ATP produce relaxation of guinea-pig isolated trachealis muscle via actions at P1 purinoceptors.
Topics: Adenosine Triphosphate; Animals; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Parasympatholytics; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Theophylline; Thioinosine; Trachea | 1996 |
P2-purinoceptor antagonists: III. Blockade of P2-purinoceptor subtypes and ecto-nucleotidases by compounds related to suramin.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Colon; Guinea Pigs; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Purinergic P2 Receptor Antagonists; Rats; Structure-Activity Relationship; Suramin; Thionucleotides; Vas Deferens | 1996 |
The possible role of ATP and PACAP as mediators of apaminsensitive NANC inhibitory junction potentials in circular muscle of guinea-pig colon.
Topics: Adenosine Triphosphate; Animals; Apamin; Colon; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyridoxal Phosphate; Receptors, Adrenergic; Receptors, Cholinergic; Suramin; Tetraethylammonium; Tetraethylammonium Compounds | 1996 |
Pressure-mediated vasoconstriction of juxtamedullary afferent arterioles involves P2-purinoceptor activation.
Topics: Adenosine Triphosphate; Animals; Arterioles; Homeostasis; Humans; Kidney Medulla; Male; Perfusion; Pressure; Purinergic Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Renal Circulation; Suramin; Time Factors; Vasoconstriction | 1996 |
Diadenosine polyphosphates induce transplasma membrane calcium influx in cultured glomerular mesangial cells.
Topics: Adenosine Triphosphate; Affinity Labels; Angiotensin II; Animals; Calcium; Cell Membrane; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Glomerular Mesangium; Male; Phospholipase D; Rats; Rats, Inbred WKY; Second Messenger Systems; Suramin; Type C Phospholipases; Vasoconstrictor Agents | 1996 |
Autoradiography of [3H]alpha,beta-methylene-ATP binding sites in medulla oblongata and spinal cord of the rat.
Topics: Adenosine Triphosphate; Animals; Autoradiography; Binding Sites; Coloring Agents; Female; Male; Medulla Oblongata; Purinergic Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Spinal Cord; Suramin; Tritium | 1997 |
Cromakalim blocks the purinergic response evoked in rat vas deferens by single-pulse electrical stimulation.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Electric Stimulation; Glyburide; Male; Norepinephrine; Potassium Channels; Prazosin; Pyrroles; Rats; Rats, Wistar; Suramin; Vas Deferens | 1997 |
Prominent sympathetic purinergic vasoconstriction in the rabbit splenic artery: potentiation by 2,2'-pyridylisatogen tosylate.
Topics: Adenosine Triphosphate; Adrenergic Agents; Animals; Electric Stimulation; Guanethidine; In Vitro Techniques; Isatin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rabbits; Receptors, Purinergic P2; Splenic Artery; Suramin; Sympathetic Nervous System; Tetrodotoxin; Vasoconstriction | 1997 |
The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding, Competitive; Blood Platelets; Calcium; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Jurkat Cells; Megakaryocytes; Membrane Proteins; Polymerase Chain Reaction; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Suramin | 1997 |
Nonadrenergic contractile response of guinea pig portal vein to electrical field stimulation mimics response to UTP but not to ATP.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Electric Stimulation; Guanethidine; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Phentolamine; Portal Vein; Reserpine; Suramin; Tetrodotoxin; Triazines; Uridine Triphosphate | 1997 |
Vasoconstrictor responses via P2X-receptors are selectively antagonized by NF023 in rabbit isolated aorta and saphenous artery.
Topics: Adenosine Triphosphate; Animals; Aorta; Arteries; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Norepinephrine; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Suramin; Vasoconstriction; Vasoconstrictor Agents | 1997 |
The interaction of diadenosine polyphosphates with P2x-receptors in the guinea-pig isolated vas deferens.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Analysis of Variance; Animals; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Lethal Dose 50; Male; Muscle Contraction; Norepinephrine; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P2; Second Messenger Systems; Suramin; Vas Deferens; Vasoconstrictor Agents | 1997 |
Characterization of alpha, beta-methylene ATP binding sites in mouse crude synaptic membranes.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Brain; Cations; Logistic Models; Male; Mice; Mice, Inbred Strains; Suramin; Synaptic Membranes; Triazines | 1997 |
Peripheral adenosine 5'-triphosphate enhances nociception in the formalin test via activation of a purinergic p2X receptor.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Drug Interactions; Male; Nociceptors; Pain Measurement; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Thionucleotides | 1997 |
Evidence for the involvement of P2-purinoceptors in the cholinergic contraction of the guinea-pig ileum.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin | 1997 |
Different contributions of ATP and noradrenaline to neurotransmission in the isolated canine intermediate auricular artery.
Topics: Adenosine Triphosphate; Animals; Arteries; Dogs; Ear; Electric Stimulation; Female; Guanethidine; In Vitro Techniques; Male; Norepinephrine; Phentolamine; Purinergic P2 Receptor Antagonists; Suramin; Sympathetic Nervous System; Sympatholytics; Synaptic Transmission; Tetrodotoxin; Vasoconstriction; Vasoconstrictor Agents | 1997 |
Evidence of adenosine 5'-triphosphate release from nerve and P2x-purinoceptor mediated contraction during electrical stimulation of rat urinary bladder smooth muscle.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Tetrodotoxin; Urinary Bladder | 1997 |
Role of ATP in fast excitatory synaptic potentials in locus coeruleus neurones of the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Kynurenic Acid; Locus Coeruleus; Male; Picrotoxin; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin | 1997 |
Enhancement by exogenous and locally generated angiotensin II of purinergic neurotransmission via angiotensin type 1 receptor in the guinea-pig isolated mesenteric artery.
Topics: Adenosine Triphosphate; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Electric Stimulation; Evoked Potentials; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Purinergic P2 Receptor Antagonists; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Suramin; Synaptic Transmission; Tetrazoles; Vasoconstrictor Agents | 1997 |
UTP induces vascular responses in the isolated and perfused canine epicardial coronary artery via UTP-preferring P2Y receptors.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antinematodal Agents; Coronary Vessels; Diltiazem; Dogs; Female; Hexokinase; Indomethacin; Male; Protein Synthesis Inhibitors; Receptors, Purinergic P2; Saponins; Suramin; Triazines; Uridine Diphosphate; Uridine Triphosphate | 1997 |
Modulation by adenine nucleotides of epileptiform activity in the CA3 region of rat hippocampal slices.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Electric Stimulation; Epilepsy; Hippocampus; In Vitro Techniques; Male; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Theophylline | 1998 |
Evidence that ATP acts at two sites to evoke contraction in the rat isolated tail artery.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Arteries; Enzyme Inhibitors; Male; Muscle Contraction; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Suramin; Tail | 1998 |
Central P2X4 and P2X6 channel subunits coassemble into a novel heteromeric ATP receptor.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Cations; Cells, Cultured; Electrophysiology; Enzyme Inhibitors; Humans; Ion Channel Gating; Kidney; Neuropeptides; Oocytes; Platelet Aggregation Inhibitors; Protons; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Suramin; Triazines; Xenopus laevis; Zinc | 1998 |
Evaluation of intrinsic modulation of synaptic transmission by ATP in mouse fast twitch muscle.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Diaphragm; Drug Antagonism; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred ICR; Motor Endplate; Muscle Contraction; Muscle Fibers, Fast-Twitch; Neuromuscular Junction; Phrenic Nerve; Purinergic P1 Receptor Antagonists; Suramin; Synaptic Transmission; Xanthines | 1998 |
Two types of relaxation-mediating P2 receptors in rat gastric circular muscle.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Apamin; Dose-Response Relationship, Drug; Gastric Mucosa; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Stomach; Suramin; Thionucleotides | 1998 |
ATP-induced, P2U purinoceptor-mediated constriction of isolated, perfused mesenteric beds of the rat.
Topics: Adenosine Triphosphate; Animals; Drug Interactions; In Vitro Techniques; Male; Mesenteric Veins; Perfusion; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Uridine Triphosphate; Vasoconstriction | 1998 |
Extracellular ATP increases [Ca2+]i in primarily cultured pig coronary smooth muscle cells via a P2Y purinoceptor subtype.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Extracellular Space; Muscle, Smooth, Vascular; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Swine; Thionucleotides; Uridine Triphosphate | 1999 |
Concomitant blockade of P2X-receptors and ecto-nucleotidases by P2-receptor antagonists: functional consequences in rat vas deferens.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Anthraquinones; Evans Blue; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Naphthalenes; Naphthalenesulfonates; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2X; Sensitivity and Specificity; Sulfonic Acids; Suramin; Triazines; Trypan Blue; Vas Deferens | 1999 |
Central CO2 chemoreception: a mechanism involving P2 purinoceptors localized in the ventrolateral medulla of the anaesthetized rat.
Topics: Adenosine Triphosphate; Anesthesia, General; Animals; Blood Pressure; Carbon Dioxide; Chemoreceptor Cells; Medulla Oblongata; Microinjections; Olivary Nucleus; Oxygen; Phrenic Nerve; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Respiratory Mechanics; Suramin | 1999 |
Cotransmission from sympathetic vasoconstrictor neurons to small cutaneous arteries in vivo.
Topics: Adenosine Triphosphate; Animals; Arteries; Constriction, Pathologic; Electric Stimulation; Female; Guinea Pigs; Male; Neurons; Neuropeptide Y; Norepinephrine; Peptides, Cyclic; Skin; Suramin; Sympathetic Nervous System; Vasoconstriction | 1999 |
Effects of activation and blockade of P2x receptors in the ventrolateral medulla on arterial pressure and sympathetic activity.
Topics: Adenosine Triphosphate; Animals; Baroreflex; Blood Pressure; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; Heart Rate; Kidney; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Glutamate; Suramin; Sympathetic Nervous System | 1999 |
Evidence for two different P2X-receptors mediating vasoconstriction of Ap5A and Ap6A in the isolated perfused rat kidney.
Topics: Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney; Male; Perfusion; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Inbred WKY; Receptors, Purinergic P2; Renal Artery; Renal Circulation; Suramin; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Cross desensitizations on contractions by P2-agonists of guinea pig ileum.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Receptors, Purinergic P2; Suramin; Tetrodotoxin | 1999 |
Different receptors mediating the inhibitory action of exogenous ATP and endogenously released purines on guinea-pig intestinal peristalsis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apamin; Female; Guinea Pigs; Ileum; In Vitro Techniques; Intestines; Male; Peristalsis; Purines; Pyridoxal Phosphate; Receptors, Purinergic; Receptors, Purinergic P2; Suramin; Thionucleotides | 1999 |
Excitatory effect of P2X receptor activation on mesenteric afferent nerves in the anaesthetised rat.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Blood Pressure; Carbolines; Electrophysiology; Heart Rate; Jejunum; Male; Mesentery; Neurons, Afferent; omega-Conotoxins; Peptides; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Serotonin; Suramin | 1999 |
Purinergic sensory neurotransmission in the urinary bladder: an in vitro study in the rat.
Topics: Adenosine Triphosphate; Animals; Male; Neurons, Afferent; Rats; Rats, Wistar; Suramin; Synaptic Transmission; Urinary Bladder | 1999 |
ATP released from perivascular nerves hyperpolarizes smooth muscle cells by releasing an endothelium-derived factor in hamster mesenteric arteries.
Topics: Adenosine Triphosphate; Animals; Cricetinae; Electric Stimulation; Endothelium, Vascular; Excitatory Postsynaptic Potentials; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Mesenteric Arteries; Mesocricetus; Microelectrodes; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Prazosin; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Triazines | 1999 |
Suramin-sensitive suppression of paired-pulse inhibition by adenine nucleotides in rat hippocampal slices.
Topics: Action Potentials; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Hippocampus; Male; Nerve Tissue Proteins; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Purinergic P2; Suramin; Theophylline | 2000 |
Endogenous ATP released by electrical field stimulation causes contraction via P2x- and P2y-purinoceptors in the isolated tail artery of rats.
Topics: Adenosine Triphosphate; Animals; Arteries; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nerve Endings; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Regional Blood Flow; Suramin; Tail; Triazines; Vasoconstriction | 1999 |
Inhibition of rat parotid ecto-ATPase activity.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrolysis; Kinetics; Membranes; Parotid Gland; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Suramin; Thionucleotides; Triazines | 1999 |
Effects of spinally administered P2X receptor agonists and antagonists on the responses of dorsal horn neurones recorded in normal, carrageenan-inflamed and neuropathic rats.
Topics: Adenosine Triphosphate; Animals; Carrageenan; Electrophysiology; Inflammation; Injections, Spinal; Male; Nerve Fibers; Nerve Fibers, Myelinated; Neurons; Peripheral Nervous System Diseases; Platelet Aggregation Inhibitors; Posterior Horn Cells; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Spinal Nerves; Suramin | 2000 |
Functional characterization of the P2X(4) receptor orthologues.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Axons; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Humans; Membrane Potentials; Mice; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Recombinant Proteins; Suramin | 2000 |
ATP as a mediator of mammalian central CO2 chemoreception.
Topics: Adenosine Triphosphate; Animals; Carbon Dioxide; Chemoreceptor Cells; Dose-Response Relationship, Drug; Iontophoresis; Male; Medulla Oblongata; Microelectrodes; Neurons; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Suramin; Theophylline | 2000 |
P2X purinoceptor-mediated excitation of trigeminal lingual nerve terminals in an in vitro intra-arterially perfused rat tongue preparation.
Topics: Adenosine Triphosphate; Age Factors; Animals; Antineoplastic Agents; Capsaicin; Dose-Response Relationship, Drug; Injections, Intra-Arterial; Lingual Nerve; Neurons, Afferent; Physical Stimulation; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Stimulation, Chemical; Suramin; Taste; Tongue | 2000 |
Development of fast purinergic transmission in the mouse vas deferens.
Topics: Adenosine Triphosphate; Adrenergic Fibers; Animals; Antineoplastic Agents; Cloning, Molecular; Electrophysiology; Gene Expression; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Muscle, Smooth; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; RNA, Messenger; Suramin; Synaptic Transmission; Vas Deferens | 2000 |
Evidence for P(2)-purinoceptors contribution in H(2)O(2)-induced contraction of rat aorta in the absence of endothelium.
Topics: Adenosine Triphosphate; Alkaloids; Analysis of Variance; Animals; Aorta; Apyrase; Benzylisoquinolines; Calcium; Calcium Channel Blockers; Catalase; Dantrolene; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Evans Blue; Hydrogen Peroxide; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nickel; Nifedipine; Procaine; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Signal Transduction; Superoxide Dismutase; Suramin; Triazines; Vasoconstrictor Agents | 2000 |
P2 purinoceptor-mediated control of rat cerebral (pial) microvasculature; contribution of P2X and P2Y receptors.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Cerebral Veins; Electrophysiology; Male; Microcirculation; Patch-Clamp Techniques; Pyridoxal Phosphate; Pyrimidine Nucleotides; Rats; Rats, Wistar; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Suramin; Vasoconstriction; Vasodilation | 2000 |
Multiple P2Y receptors mediate contraction in guinea pig mesenteric vein.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Male; Mesenteric Artery, Inferior; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Chloride; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Pyrimidine Nucleotides; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin; Uridine Triphosphate | 2000 |
Single channel properties of P2X ATP receptors in outside-out patches from rat hippocampal granule cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Cytoplasmic Granules; Dentate Gyrus; Electrophysiology; Hippocampus; In Vitro Techniques; Ion Channel Gating; Ion Channels; Male; Membrane Potentials; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin | 2000 |
Regulation of the development of allodynia by intrathecally administered P2 purinoceptor agonists and antagonists in mice.
Topics: Adenosine Triphosphate; Animals; Dinoprostone; Dizocilpine Maleate; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Neuroprotective Agents; Oxytocics; Pain; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Suramin | 2000 |
Characterisation of ATP-induced facilitation of transmission in rat hippocampus.
Topics: Adenosine Deaminase; Adenosine Triphosphate; Animals; Caffeine; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Synaptic Transmission; Theophylline | 2000 |
Properties of P2X and P2Y receptors are dependent on artery diameter in the rat mesenteric bed.
Topics: Adenosine Triphosphate; Animals; Calcium; Dose-Response Relationship, Drug; Immunohistochemistry; In Vitro Techniques; Male; Mesenteric Arteries; Phenylephrine; Potassium Chloride; Protein Subunits; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Uridine Triphosphate; Vasoconstriction | 2000 |
Lack of run-down of smooth muscle P2X receptor currents recorded with the amphotericin permeabilized patch technique, physiological and pharmacological characterization of the properties of mesenteric artery P2X receptor ion channels.
Topics: Adenosine Triphosphate; Amphotericin B; Animals; Calcium; Cell Membrane Permeability; Dose-Response Relationship, Drug; Guanosine Triphosphate; Immunohistochemistry; Ion Channels; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Receptors, Purinergic P2X4; Receptors, Purinergic P2X5; Receptors, Purinergic P2X7; Suramin; Thionucleotides; Time Factors | 2000 |
Multiple P2X receptors on guinea-pig pelvic ganglion neurons exhibit novel pharmacological properties.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Electrophysiology; Ganglia, Autonomic; Guinea Pigs; Hydrogen-Ion Concentration; Male; Mice; Neurons; Nodose Ganglion; Patch-Clamp Techniques; Pelvis; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Suramin; Zinc | 2001 |
Analysis of purine- and pyrimidine-induced vascular responses in the isolated rat cerebral arteriole.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Arterioles; Cerebral Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroprusside; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y2; Suramin; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction; Vasodilation | 2001 |
Mechanism of prolonged vasorelaxation to ATP in the rat isolated mesenteric arterial bed.
Topics: Adenosine Triphosphate; Animals; Capsaicin; Cardiotonic Agents; Cardiovascular Agents; Charybdotoxin; Drug Interactions; Electric Stimulation; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Isotonic Solutions; Male; Mesenteric Arteries; Neurons, Afferent; Ouabain; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Tetraethylammonium; Theophylline; Vasodilation | 2001 |
Effects of ATP on intracellular calcium dynamics of the perineurium of peripheral nerve bundles.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anesthetics, Local; Animals; Antineoplastic Agents; Calcium; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Lidocaine; Male; Microscopy, Confocal; Peripheral Nerves; Rats; Rats, Inbred WKY; Sciatic Nerve; Suramin; Tetraethylammonium; Tetrodotoxin; Thapsigargin; Triazines; Uridine Triphosphate | 2000 |
Nucleotide-evoked relaxation of rat vas deferens--a possible role for endogenous ATP released upon alpha(1)-adrenoceptor stimulation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Relaxation; Norepinephrine; Nucleotides; Potassium; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Pyrophosphatases; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Suramin; Theophylline; Thionucleotides; Triazines; Vas Deferens; Vasoconstrictor Agents | 2001 |
Effect on urinary bladder function and arterial blood pressure of the activation of putative purine receptors in brainstem areas.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Brain Mapping; Brain Stem; Electric Stimulation; Female; Glutamic Acid; Locus Coeruleus; Microinjections; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Suramin; Urinary Bladder | 2001 |
Extracellular ATP activates a P2 receptor in necturus erythrocytes during hypotonic swelling.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cell Size; Erythrocytes; Gramicidin; Hemolysis; Necturus maculosus; Osmotic Fragility; Patch-Clamp Techniques; Potassium; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Suramin; Thionucleotides | 2001 |
Roles of norepinephrine and ATP in sympathetically evoked vasoconstriction in rat tail and hindlimb in vivo.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Femoral Artery; Hindlimb; Male; Muscle, Skeletal; Norepinephrine; Phentolamine; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Skin; Suramin; Sympathetic Nervous System; Synaptic Transmission; Tail; Vascular Resistance; Vasoconstriction | 2001 |
Effect of in vivo and in vitro ethanol on adrenergic and purinergic responses of the bisected rat vas deferens to low and high frequency pulses.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Central Nervous System Depressants; Electric Stimulation; Ethanol; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Rats; Rats, Wistar; Receptors, Purinergic; Suramin; Sympathetic Nervous System; Vas Deferens | 2001 |
Involvement of purinergic signalling in central mechanisms of body temperature regulation in rats.
Topics: Adenosine Triphosphate; Animals; Body Temperature Regulation; Brain; Fever; Hypothalamus; Injections, Intraventricular; Lipopolysaccharides; Male; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Signal Transduction; Suramin | 2002 |
Adenosine 5'-triphosphate-evoked calcium responses in terminal Schwann cells of lanceolate sensory endings isolated from rat vibrissae.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Dose-Response Relationship, Drug; Fluorescent Dyes; Intracellular Fluid; Male; Mechanoreceptors; Neurons, Afferent; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; S100 Proteins; Schwann Cells; Signal Transduction; Suramin; Touch; Uridine Triphosphate; Vibrissae | 2002 |
[Effect of activation and blockade of central P2X receptors on body temperature].
Topics: Adenosine Triphosphate; Animals; Body Temperature Regulation; Hypothalamus; Immunohistochemistry; Male; Medulla Oblongata; Neurons, Afferent; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Stress, Physiological; Suramin; Temperature | 2002 |
Potentiation of inhibitory glycinergic neurotransmission by Zn2+: a synergistic interplay between presynaptic P2X2 and postsynaptic glycine receptors.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fetus; Glycine; Humans; Immunohistochemistry; Neural Inhibition; Presynaptic Terminals; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Glycine; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X4; Spinal Cord; Suramin; Synaptic Membranes; Synaptic Transmission; Zinc | 2002 |
P2X purinergic receptor antagonist accelerates skin barrier repair and prevents epidermal hyperplasia induced by skin barrier disruption.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Calcium; Cells, Cultured; Epidermis; Fluorescent Dyes; Hyperplasia; Immunohistochemistry; Keratinocytes; Male; Mice; Mice, Hairless; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Reverse Transcriptase Polymerase Chain Reaction; Suramin; Water; Wound Healing | 2002 |
Neurotransmitters involved in the fast inhibitory junction potentials in mouse distal colon.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apamin; Colon; Dose-Response Relationship, Drug; Male; Membrane Potentials; Mice; Neuromuscular Junction; Neuropeptides; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Suramin; Tetrodotoxin; Thionucleotides | 2003 |
Adenosine 5'-triphosphate (ATP) is an excitatory cotransmitter with noradrenaline to the smooth muscle of the rat prostate gland.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Immunohistochemistry; Male; Muscle, Smooth; Nerve Endings; Neurotransmitter Agents; Norepinephrine; Prazosin; Prostate; Purine Nucleotides; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Receptors, Purinergic P2; Suramin | 2003 |
Discrete but simultaneous release of adenine nucleotides and serotonin from mouse megakaryocytes as detected with patch- and carbon-fiber electrodes.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Carbon; Carbon Fiber; Electrodes; Electrophysiology; Megakaryocytes; Mice; Mice, Inbred BALB C; Patch-Clamp Techniques; Platelet Activation; Pyridoxal Phosphate; Serotonin; Suramin; Time Factors | 2004 |
Functional evidence that ATP or a related purine is an inhibitory NANC neurotransmitter in the mouse jejunum: study on the identity of P2X and P2Y purinoceptors involved.
Topics: Adenosine Triphosphate; Animals; Apamin; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Jejunum; Mice; Muscle Relaxation; Muscle, Smooth; Neurotransmitter Agents; Nitric Oxide Synthase; Nitroarginine; Protein Isoforms; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Synaptic Transmission; Thionucleotides | 2003 |
Desensitization masks nanomolar potency of ATP for the P2X1 receptor.
Topics: Adenosine Triphosphate; Affinity Labels; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Electrophysiology; Kinetics; Models, Biological; Models, Chemical; Oocytes; Plasmids; Protein Binding; Receptors, Purinergic P2; Receptors, Purinergic P2X; Recombinant Fusion Proteins; Suramin; Thionucleotides; Time Factors; Xenopus | 2004 |
[3H]alpha,beta-methylene ATP binding to P2X purinoceptor is unaffected by volatile anaesthetics.
Topics: Adenosine Triphosphate; Analysis of Variance; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Isoflurane; Male; Methyl Ethers; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Sevoflurane; Suramin; Synaptic Membranes; Synaptic Transmission; Tritium | 2004 |
Purinergic receptors coupled to intracellular Ca2+ signals and exocytosis in rat prostate neuroendocrine cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cell Membrane; Electric Capacitance; Electrophysiology; Exocytosis; Male; Microscopy, Fluorescence; Neurosecretory Systems; Prostate; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Uridine Diphosphate; Uridine Triphosphate | 2004 |
ATP inhibits pump activity of lymph vessels via adenosine A1 receptor-mediated involvement of NO- and ATP-sensitive K+ channels.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Antineoplastic Agents; Arginine; Cardiovascular Agents; Endothelium; Enzyme Inhibitors; Glyburide; Indomethacin; Lymphatic System; Male; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Rats; Rats, Wistar; Receptor, Adenosine A1; Suramin; Xanthines | 2004 |
Adenosine 5'-triphosphate and noradrenaline are excitatory cotransmitters to the fibromuscular stroma of the guinea pig prostate gland.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Immunohistochemistry; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Prostate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Receptors, Purinergic P2X4; Suramin; Tetrodotoxin; Thionucleotides | 2004 |
Direct excitation of hypocretin/orexin cells by extracellular ATP at P2X receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Analysis of Variance; Animals; Bicuculline; Choline; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; Green Fluorescent Proteins; Hypothalamus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Neuropeptides; Orexin Receptors; Orexins; Patch-Clamp Techniques; Pyridoxal Phosphate; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Suramin; Tetrodotoxin | 2005 |
Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Astrocytoma; Calcium; Cell Line; Cell Line, Tumor; Glutamic Acid; Hippocampus; Kidney; Male; Potassium; Pyramidal Cells; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Recombinant Fusion Proteins; RNA, Messenger; Subcellular Fractions; Suramin; Synaptosomes; Transfection; Triazines; Triazoles; Xanthines | 2005 |
Neocuproine, a copper (I) chelator, potentiates purinergic component of vas deferens contractions elicited by electrical field stimulation.
Topics: Adenosine Triphosphate; Animals; Chelating Agents; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Nitric Oxide; Phenanthrolines; Prazosin; Rats; Rats, Wistar; Receptors, Purinergic; Suramin; Vas Deferens | 2005 |
Rho kinase inhibitors reduce neurally evoked contraction of the rat tail artery in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Amides; Animals; Arteries; Clonidine; Electric Stimulation; Electrophysiology; Female; Idazoxan; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Phenylephrine; Prazosin; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Purinergic P2 Receptor Antagonists; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; Suramin; Tail; Vasoconstriction | 2005 |
Enhanced neurally evoked responses and inhibition of norepinephrine reuptake in rat mesenteric arteries after spinal transection.
Topics: Adenosine Triphosphate; Animals; Autonomic Dysreflexia; Electric Stimulation; Female; Mesenteric Arteries; Methoxamine; Norepinephrine; Phenylephrine; Potassium; Prazosin; Rats; Rats, Wistar; Spinal Cord Injuries; Suramin; Vasoconstriction | 2006 |
The novel suramin analogue NF864 selectively blocks P2X1 receptors in human platelets with potency in the low nanomolar range.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Blood Platelets; Calcium; Cell Shape; Dose-Response Relationship, Drug; Humans; Least-Squares Analysis; Linear Models; Phenylmercury Compounds; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Suramin; Thionucleotides | 2005 |
Activation of P2Y receptor enhances high-molecular compound absorption from rat ileum.
Topics: Adenosine Triphosphate; Animals; Dextrans; Fluorescein-5-isothiocyanate; Ileum; Intestinal Absorption; Male; Nucleotides; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Thionucleotides | 2006 |
Altered neurogenic and mechanical responses to acetylcholine, ATP and substance P in detrusor from rat with outlet obstruction.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Cholinergic Agonists; Cyclooxygenase Inhibitors; Electric Stimulation; Female; In Vitro Techniques; Indomethacin; Mandelic Acids; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Substance P; Suramin; Urethra; Urinary Bladder; Urinary Bladder Neck Obstruction | 2006 |
Frequency encoding of cholinergic- and purinergic-mediated signaling to mouse urinary bladder smooth muscle: modulation by BK channels.
Topics: Adenosine Triphosphate; Animals; Atropine; Cholinergic Agents; Electric Stimulation; Female; Immunohistochemistry; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channels; Male; Mice; Muscle Contraction; Muscle, Smooth; Neurons; Parasympathetic Nervous System; Peptides; Receptors, Muscarinic; Receptors, Purinergic; Suramin; Urinary Bladder | 2007 |
In vitro characterization of parasympathetic and sympathetic responses in cyclophosphamide-induced cystitis in the rat.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cyclophosphamide; Cystitis; Diamines; Electric Stimulation; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Phentolamine; Piperidines; Pirenzepine; Propranolol; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Suramin; Sympatholytics; Urinary Bladder | 2007 |
Sympathetic vasoconstrictor regulation of mouse colonic submucosal arterioles is altered in experimental colitis.
Topics: Adenosine Triphosphate; Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arterioles; Colitis; Colon; Disease Models, Animal; Electric Stimulation; Enteric Nervous System; Guanethidine; Intestinal Mucosa; Male; Mice; Microscopy, Video; Norepinephrine; Phenylephrine; Prazosin; Purinergic P2 Receptor Antagonists; Receptors, Adrenergic, alpha-1; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin; Sympathetic Nervous System; Tetrodotoxin; Time Factors; Trinitrobenzenesulfonic Acid; Up-Regulation; Vasoconstriction | 2007 |
Ca2+ signaling in injured in situ endothelium of rat aorta.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta, Abdominal; Aorta, Thoracic; Calcium Signaling; Endothelium, Vascular; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Suramin | 2008 |
Luminal ATP-induced contraction of rabbit pulmonary arteries and role of purinoceptors in the regulation of pulmonary arterial pressure.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Calcium Signaling; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Female; Hypoxia; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Perfusion; Pulmonary Artery; Pulmonary Circulation; Rabbits; Receptors, Purinergic P2; Respiration, Artificial; Spectrometry, Fluorescence; Suramin; Uridine Triphosphate; Vasoconstriction; Vasodilation; Video Recording | 2008 |
Pharmacological properties of P2 receptors on rat otic parasympathetic ganglion neurons.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Ganglia, Parasympathetic; Rats; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Suramin; Uridine Triphosphate | 2008 |
Activation of cholinergic receptors blocks non-adrenergic non-cholinergic contractions in the rat urinary bladder.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Antineoplastic Agents; Atropine; Calcium Channel Agonists; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Electric Stimulation; Female; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Physostigmine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Suramin; Urinary Bladder | 2008 |
Dual effect of ATP on glucose-induced insulin secretion in HIT-T15 cells.
Topics: Adenosine Triphosphate; Animals; Cell Line; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activators; Feedback, Physiological; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Protein Kinase C; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Suramin; Tetradecanoylphorbol Acetate; Thionucleotides | 2008 |
Assessment and characterization of purinergic contractions and relaxations in the rat urinary bladder.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Drug Antagonism; Electric Stimulation; Glyburide; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Theophylline; Uracil Nucleotides; Urinary Bladder; Xanthines | 2010 |
Functional ligand-gated purinergic receptors (P2X) in rat vestibular ganglion neurons.
Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Evoked Potentials, Auditory; Ganglia, Sensory; Ligands; Models, Animal; Neural Conduction; Neurons; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin; Vestibular Nerve | 2010 |
Purinoreceptor-mediated current in myocytes from renal resistance arteries.
Topics: Adenosine Triphosphate; Animals; Arteries; Kidney; Kinetics; Male; Membrane Potentials; Microdissection; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Organ Specificity; Osmolar Concentration; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Inbred WKY; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Suramin | 2010 |
Characterization of nestin expression in the spinal cord of GFP transgenic mice after peripheral nerve injury.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Proliferation; Green Fluorescent Proteins; Intermediate Filament Proteins; Lumbar Vertebrae; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nestin; Neuroglia; Pyridoxal Phosphate; Spinal Cord; Spinal Cord Injuries; Spinal Nerves; Stem Cells; Suramin | 2010 |
Differential effects of uridine adenosine tetraphosphate on purinoceptors in the rat isolated perfused kidney.
Topics: Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Endothelium, Vascular; Kidney; Male; Nitric Oxide Synthase; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Inbred WKY; Receptors, Purinergic; Suramin; Triazines; Vasoconstriction; Vasodilation | 2010 |
Purinergic mechanisms of lateral parabrachial nucleus facilitate sodium depletion-induced NaCl intake.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Drug Administration Routes; Food Deprivation; Male; Pons; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2X; Sodium Chloride; Sodium Chloride, Dietary; Sucrose; Suramin; Time Factors; Water Deprivation | 2011 |
Maintained tubuloglomerular feedback responses during acute inhibition of P2 purinergic receptors in mice.
Topics: Adenosine Triphosphate; Animals; Arterioles; Blood Pressure; Feedback, Physiological; Glomerular Filtration Rate; Kidney Glomerulus; Kidney Tubules; Male; Mice; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Vasoconstriction | 2011 |
Perspective on the role of P2X-purinoceptor activation in human vas deferens contractility.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Amides; Apamin; Calcium Channel Agonists; Calcium Channels, L-Type; Humans; Large-Conductance Calcium-Activated Potassium Channels; Male; Muscle Contraction; Norepinephrine; Peptides; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Purinergic P2X Receptor Agonists; Pyridines; Pyrophosphatases; Pyrroles; Receptors, Purinergic P2X; rho-Associated Kinases; Suramin; Vas Deferens | 2012 |
Extracellular ATP signaling in equine digital blood vessels.
Topics: Adenosine Triphosphate; Animals; Arteries; Electric Stimulation; Female; Horses; In Vitro Techniques; Male; Methoxamine; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin; Uridine Triphosphate; Vasoconstriction; Vasoconstrictor Agents; Veins | 2013 |
BRL37344, a β3-adrenergic receptor agonist, decreases nerve-evoked contractions in human detrusor smooth muscle isolated strips: role of BK channels.
Topics: Adenosine Triphosphate; Adrenergic beta-3 Receptor Agonists; Aged; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Ethanolamines; Female; Humans; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Male; Middle Aged; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Peptides; Potassium Channel Blockers; Purinergic Agonists; Purinergic Antagonists; Suramin; Urinary Bladder | 2013 |
α,β-meATP mimics the effects of the purinergic neurotransmitter in the human and rat colon.
Topics: Adenosine Triphosphate; Aged; Animals; Apamin; Colon; Deoxyadenine Nucleotides; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purinergic Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats, Sprague-Dawley; Receptors, Purinergic P2Y1; Suramin | 2014 |
Paracrine effect of carbon monoxide - astrocytes promote neuroprotection through purinergic signaling in mice.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Astrocytes; Carbon Monoxide; Coculture Techniques; Cysteine; Extracellular Space; Gene Silencing; Glycyrrhetinic Acid; Mice, Inbred C57BL; Models, Biological; Neurons; Neuroprotection; Paracrine Communication; Pyrimidines; Receptor, trkB; Receptors, Adenosine A2; Receptors, Purinergic; Serine; Signal Transduction; Suramin; Thioinosine; Triazoles; Xanthines | 2016 |
Neuropeptide Y facilitates P2X1 receptor-dependent vasoconstriction via Y1 receptor activation in small mesenteric arteries during sympathetic neurogenic responses.
Topics: Adenosine Triphosphate; Adrenergic alpha-1 Receptor Antagonists; Animals; Benzenesulfonates; Calcium Channel Blockers; Calcium Channels, L-Type; Male; Mesenteric Arteries; Mice, Inbred C57BL; Neuropeptide Y; Nifedipine; Prazosin; Receptors, Neuropeptide Y; Receptors, Purinergic P2X1; Suramin; Sympathetic Nervous System; Vasoconstriction | 2021 |