Page last updated: 2024-08-16

sumatriptan and prazosin

sumatriptan has been researched along with prazosin in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (14.29)	18.2507
2000's	10 (47.62)	29.6817
2010's	8 (38.10)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Baez, M; Cohen, ML; Cushing, DJ; Kursar, JD; Schenck, K	1
Centurión, D; De Vries, P; Rabelo, G; Sánchez-López, A; Saxena, P; Villalón, CM	1
De Vries, P; Heiligers, JP; Saxena, PR; Trion, M; Villalón, CM; Willems, EW	1
Chen, J; Purdy, RE; Yildiz, O	1
Cordi, AA; Ragonnet, C; Vayssettes-Courchay, C; Verbeuren, TJ	1
Bidouard, JP; Caille, D; Gautier, E; Grosset, A; Janiak, P; La Rochelle, CD; O'Connor, SE; Robineau, P	1
Alanezi, KH; Cinà, CS; Safar, HA	1

Reviews

1 review(s) available for sumatriptan and prazosin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

20 other study(ies) available for sumatriptan and prazosin

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Serotonin-induced contraction in canine coronary artery and saphenous vein: role of a 5-HT1D-like receptor. Life sciences, 1994, Volume: 54, Issue:22 Topics: 5-Methoxytryptamine; Adrenergic alpha-Antagonists; Animals; Base Sequence; Blotting, Southern; Coronary Vessels; Dioxanes; DNA Primers; Dogs; Dose-Response Relationship, Drug; Gene Expression; Idazoxan; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth, Vascular; Piperazines; Polymerase Chain Reaction; Prazosin; Receptors, Serotonin; RNA, Messenger; Saphenous Vein; Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines	1994
Canine external carotid vasoconstriction to methysergide, ergotamine and dihydroergotamine: role of 5-HT1B/1D receptors and alpha2-adrenoceptors. British journal of pharmacology, 1999, Volume: 126, Issue:3 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Flow Velocity; Carotid Arteries; Clonidine; Dihydroergotamine; Dogs; Ergotamine; Female; Hemodynamics; Male; Methysergide; Oxadiazoles; Phenylephrine; Piperazines; Prazosin; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin Antagonists; Sumatriptan; Vasoconstriction; Vasoconstrictor Agents; Yohimbine	1999
Pharmacological evidence that alpha1-and alpha2-adrenoceptors mediate vasoconstriction of carotid arteriovenous anastomoses in anaesthetized pigs. British journal of pharmacology, 1999, Volume: 127, Issue:5 Topics: Anesthesia; Animals; Arteriovenous Anastomosis; Azepines; Carotid Arteries; Hemodynamics; Migraine Disorders; Oxadiazoles; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Sumatriptan; Swine; Vasoconstriction	1999
Phenylephrine precontraction increases the sensitivity of rabbit femoral artery to serotonin by enabling 5-HT1-like receptors. Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:6 Topics: Animals; Dose-Response Relationship, Drug; Femoral Artery; In Vitro Techniques; Oxadiazoles; Phenylephrine; Piperazines; Prazosin; Rabbits; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Specific Pathogen-Free Organisms; Sumatriptan; Vasoconstriction	2000
In vivo analysis of adrenergic and serotoninergic constrictions of the rabbit saphenous vein. European journal of pharmacology, 2000, Nov-24, Volume: 408, Issue:3 Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Benzazepines; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Ergolines; Imidazoles; Indoles; Injections, Intravenous; Isoindoles; Oxadiazoles; Peripheral Nervous System; Phenylephrine; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Receptors, Serotonin; Saphenous Vein; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Sumatriptan; Tetrahydronaphthalenes; Time Factors; Ultrasonography, Doppler; Vasoconstrictor Agents	2000
Cardiovascular effects of SL65.0472, a 5-HT receptor antagonist. European journal of pharmacology, 2001, Mar-02, Volume: 414, Issue:2-3 Topics: Animals; Antihypertensive Agents; Blood Pressure; Dogs; Heart Rate; Hemodynamics; Male; Piperazines; Prazosin; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Sumatriptan; Vasoconstrictor Agents	2001
Successful treatment of threatening limb loss ischemia of the upper limb caused by ergotamine. A case report and review of the literature. The Journal of cardiovascular surgery, 2002, Volume: 43, Issue:2 Topics: Administration, Oral; Adrenergic alpha-Antagonists; Angiography; Arm; Arterial Occlusive Diseases; Ergotamine; Female; Follow-Up Studies; Humans; Ischemia; Middle Aged; Migraine Disorders; Prazosin; Serotonin Antagonists; Sumatriptan; Time Factors; Vasoconstrictor Agents	2002