Page last updated: 2024-08-16

sumatriptan and nitroglycerin

sumatriptan has been researched along with nitroglycerin in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (26.32)18.2507
2000's7 (18.42)29.6817
2010's17 (44.74)24.3611
2020's4 (10.53)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Alessandri, M; Fanciullacci, M; Figini, M; Geppetti, P; Michelacci, S1
Feldman, R; Mancini, GB; Palmer, J; Zimmerman, M1
Karageorgiou, C; Tagaris, G; Thomaides, T1
Eichler, HG; Findl, O; Graselli, U; Krejcy, K; Schmetterer, L; Singer, EA; Wolzt, M1
Saxena, PR; Van Gelderen, EM1
Iversen, HK; Olesen, J1
Fagius, J; Nordin, M; Waldenlind, E1
Forrest, A; Fullerton, T; Gengo, FM; Komorowski-Swiatek, D1
Dormehl, IC; Oliver, DW1
Hunter, AJ; Manning, P; McNeil, CJ; Parsons, AA; Read, SJ1
Chadaide, Z; Csillik, B; Knyihár-Csillik, E; Tajti, J; Vécsei, L1
Pardutz, A; Schoenen, J; Szatmári, E; Vecsei, L1
Bagdy, G; Jakab, B; Juhasz, G; Nemeth, J; Szolcsanyi, J; Zsombok, T1
Camilleri, M; Coulie, BJ; Farrugia, G; Locke, GR; Meulemans, A; Schuurkes, JA; Szurszewski, JH; Xue, L1
de Hoon, J; Van der Schueren, B; Vanmolkot, F1
Sessle, BJ; Yao, D1
Ahn, AH; Basbaum, AI; Bates, EA; Brennan, KC; Charles, AC; Fu, YH; Nikai, T; Ptácek, LJ1
Edvinsson, L; Iversen, HK; Jansen-Olesen, I; Kruuse, C; Olesen, J1
Boeijinga, P; Danjou, P; Demazières, A; Djupesland, PG; Flint, A; Hewson, G; Luthringer, R; Sheldrake, CD1
Goadsby, PJ; Mathias, CJ; Viana, M1
Asghar, MS1
Charles, A; Evans, CJ; McGuire, B; Pradhan, AA; Smith, ML; Tarash, I1
Carøe Nordgaard, J; Gammeltoft, S; Kruse, LS; Kruuse, CR1
Jensen, C; Riddle, M1
Charles, A; McGuire, B; Pradhan, AA; Tarash, I; Tipton, AF1
Ferrari, LF; Green, PG; Levine, JD1
Davis, ME; Davis, RE; Johnson, AP; Smitherman, TA; Staszko, SM; Sufka, KJ1
Andreou, AP; Jones, MG; McMahon, SB; Spanswick, D1
Knapp, L; Kocsis, K; Szita, B; Toldi, J; Vécsei, L1
Ben Aissa, M; Bennett, BM; Bertels, Z; Gaisina, IN; Gandhi, R; Lee, SH; Litosh, V; Moye, LS; Novack, M; Pradhan, AA; Thatcher, GR; Tipton, AF; Wang, Y1
Bolboacă, SD; Bulboacă, AC; Bulboacă, AE; Porfire, A; Sfrângeu, CA; Stănescu, IC; Tefas, L1
Crombie, A; Dripps, I; Moye, LS; Pradhan, AA; Sheets, Z; Tipton, AF; Violin, JD1
Akerman, S; Bose, P; Goadsby, PJ; Hoffmann, JR; Holland, PR; Karsan, N; Romero-Reyes, M1
Cao, YQ; Cloud, ME; Czerpaniak, K; Hotchkiss, RS; Huang, L; Li, D; Liu, X; Unsinger, J; Zhang, J1
Ashina, M; Christensen, SL; Ernstsen, C; Guo, S; Hay-Schmidt, A; Kristensen, DM; Olesen, J1
Iurkova, PM; Kamshilin, AA; Nippolainen, E; Potapenko, AV; Sokolov, AY; Volynsky, MA; Zaytsev, VV1
Alharbi, HM; Almari, AH; Batool, S; Din, FU; Fatease, AA; Lahiq, AA; Shafique, U; Sohail, S1

Reviews

2 review(s) available for sumatriptan and nitroglycerin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Effects of glyceryl trinitrate and calcitonin gene-related peptide on BOLD signal and arterial diameter: methodological studies by fMRI and MRA.
    Danish medical journal, 2012, Volume: 59, Issue:7

    Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Brain; Calcitonin Gene-Related Peptide; Cerebral Arteries; Female; Headache; Hemodynamics; Humans; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Male; Middle Aged; Nitroglycerin; Signal Processing, Computer-Assisted; Sumatriptan; Vasoconstrictor Agents; Vasodilator Agents; Young Adult

2012

Trials

8 trial(s) available for sumatriptan and nitroglycerin

ArticleYear
Glyceryl trinitrate reversal of post-sumatriptan coronary artery narrowing.
    Lancet (London, England), 1995, May-27, Volume: 345, Issue:8961

    Topics: Coronary Angiography; Coronary Disease; Coronary Vasospasm; Coronary Vessels; Humans; Injections, Intra-Arterial; Injections, Subcutaneous; Nitroglycerin; Placebos; Sumatriptan

1995
Cerebral and ocular hemodynamic effects of sumatriptan in the nitroglycerin headache model.
    Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:2

    Topics: Adult; Analysis of Variance; Blood Flow Velocity; Cerebrovascular Circulation; Double-Blind Method; Headache; Hemodynamics; Humans; Injections, Subcutaneous; Male; Nitroglycerin; Ophthalmic Artery; Reference Values; Retinal Vessels; Sumatriptan; Vasoconstrictor Agents; Vasodilator Agents

1996
Headache induced by a nitric oxide donor (nitroglycerin) responds to sumatriptan. A human model for development of migraine drugs.
    Cephalalgia : an international journal of headache, 1996, Volume: 16, Issue:6

    Topics: Adult; Blood Flow Velocity; Brain; Cross-Over Studies; Double-Blind Method; Female; Headache; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Sumatriptan; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents

1996
The pharmacodynamics of sumatriptan in nitroglycerin-induced headache.
    Journal of clinical pharmacology, 1999, Volume: 39, Issue:1

    Topics: Adult; Analysis of Variance; Area Under Curve; Brain; Cerebral Arteries; Electrocardiography; Headache; Humans; Male; Migraine Disorders; Nitroglycerin; Pain; Regional Blood Flow; Serotonin Receptor Agonists; Severity of Illness Index; Sumatriptan; Ultrasonography, Doppler, Transcranial; Vasodilator Agents

1999
Sumatriptan causes parallel decrease in plasma calcitonin gene-related peptide (CGRP) concentration and migraine headache during nitroglycerin induced migraine attack.
    Cephalalgia : an international journal of headache, 2005, Volume: 25, Issue:3

    Topics: Biomarkers; Calcitonin Gene-Related Peptide; Female; Humans; Middle Aged; Migraine without Aura; Nitroglycerin; Severity of Illness Index; Sumatriptan; Treatment Outcome; Vasoconstrictor Agents

2005
Calcitonin gene-related peptide (CGRP) levels during glyceryl trinitrate (GTN)-induced headache in healthy volunteers.
    Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:4

    Topics: Adult; Calcitonin Gene-Related Peptide; Cross-Over Studies; Female; Headache; Humans; Male; Neuropeptide Y; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Reference Values; Somatostatin; Sumatriptan; Vasoactive Intestinal Peptide; Vasoconstrictor Agents

2010
Rapid absorption of sumatriptan powder and effects on glyceryl trinitrate model of headache following intranasal delivery using a novel bi-directional device.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:9

    Topics: Absorption; Administration, Intranasal; Adult; Drug Delivery Systems; Electroencephalography; Female; Humans; Injections, Subcutaneous; Male; Migraine Disorders; Nitroglycerin; Powders; Serotonin Receptor Agonists; Sumatriptan

2009
Nitroglycerine triggers triptan-responsive cranial allodynia and trigeminal neuronal hypersensitivity.
    Brain : a journal of neurology, 2019, 01-01, Volume: 142, Issue:1

    Topics: Adolescent; Adult; Aspirin; Double-Blind Method; Humans; Hyperalgesia; Middle Aged; Migraine Disorders; Nitroglycerin; Spinal Nerves; Sumatriptan; Trigeminal Nerve; Young Adult

2019

Other Studies

28 other study(ies) available for sumatriptan and nitroglycerin

ArticleYear
Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attack.
    Pain, 1995, Volume: 60, Issue:2

    Topics: Adult; Calcitonin Gene-Related Peptide; Cluster Headache; Humans; Male; Nitroglycerin; Remission Induction; Substance P; Sumatriptan

1995
EEG and topographic frequency analysis in migraine attack before and after sumatriptan infusion.
    Headache, 1996, Volume: 36, Issue:2

    Topics: Adult; Electroencephalography; Female; Humans; Injections, Subcutaneous; Male; Migraine Disorders; Nitroglycerin; Signal Processing, Computer-Assisted; Sumatriptan

1996
Nitroglycerin-induced headache.
    Cephalalgia : an international journal of headache, 1996, Volume: 16, Issue:6

    Topics: Arteriovenous Anastomosis; Dose-Response Relationship, Drug; Head; Headache; Humans; Migraine Disorders; Nitric Oxide; Nitroglycerin; Sumatriptan; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

1996
Sympathetic vasoconstrictor outflow to extremity muscles in cluster headache. Recordings during spontaneous and nitroglycerin-induced attacks.
    Headache, 1997, Volume: 37, Issue:6

    Topics: Adult; Animals; Baroreflex; Cluster Headache; Female; Humans; Male; Middle Aged; Muscles; Nitroglycerin; Peroneal Nerve; Rats; Sumatriptan; Sympathetic Nervous System

1997
Cerebral blood flow effects of the nitric oxide donor, nitroglycerin and its drug combinations in the non-human primate model.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:9

    Topics: Acetazolamide; Algorithms; Animals; Blood Pressure; Brain; Calcium Channel Blockers; Carbonic Anhydrase Inhibitors; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Drug Combinations; Heart Rate; Male; Nimodipine; Nitric Oxide Donors; Nitroglycerin; Papio; Radionuclide Imaging; Sumatriptan; Vasoconstrictor Agents; Vasodilator Agents

1999
Effects of sumatriptan on nitric oxide and superoxide balance during glyceryl trinitrate infusion in the rat. Implications for antimigraine mechanisms.
    Brain research, 1999, Nov-13, Volume: 847, Issue:1

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Free Radicals; Infusions, Intravenous; Laser-Doppler Flowmetry; Male; Migraine Disorders; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley; Sumatriptan; Superoxides

1999
Functional immunohistochemistry of neuropeptides and nitric oxide synthase in the nerve fibers of the supratentorial dura mater in an experimental migraine model.
    Microscopy research and technique, 2001, May-01, Volume: 53, Issue:3

    Topics: Animals; Capillaries; Dura Mater; Electric Stimulation; Female; Immunohistochemistry; Indoles; Male; Microscopy, Electron; Migraine Disorders; Nerve Endings; Nerve Fibers; Neuropeptides; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroglycerin; Pyrrolidines; Rats; Rats, Wistar; Serotonin Receptor Agonists; Sumatriptan; Trigeminal Ganglion; Tryptamines; Vasoconstrictor Agents

2001
Nitroglycerin-induced nNOS increase in rat trigeminal nucleus caudalis is inhibited by systemic administration of lysine acetylsalicylate but not of sumatriptan.
    Cephalalgia : an international journal of headache, 2004, Volume: 24, Issue:6

    Topics: Animals; Aspirin; Enzyme Activation; Lysine; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroglycerin; Rats; Rats, Wistar; Sumatriptan; Trigeminal Nucleus, Spinal

2004
Effect of modulation of serotonergic, cholinergic, and nitrergic pathways on murine fundic size and compliance measured by ultrasonomicrometry.
    American journal of physiology. Gastrointestinal and liver physiology, 2006, Volume: 290, Issue:1

    Topics: Animals; Atropine; Bethanechol; Buspirone; Gastric Fundus; Male; Mice; Muscle Contraction; Muscle, Smooth; Nitroglycerin; Reproducibility of Results; Serous Membrane; Signal Transduction; Sumatriptan; Ultrasonography

2006
Sumatriptan causes parallel decrease in plasma CGRP concentration and migraine headache during nitroglycerin-induced migraine attack.
    Cephalalgia : an international journal of headache, 2006, Volume: 26, Issue:8

    Topics: Biomarkers; Calcitonin Gene-Related Peptide; Female; Humans; Middle Aged; Migraine without Aura; Nitroglycerin; Severity of Illness Index; Sumatriptan; Treatment Outcome; Vasoconstrictor Agents

2006
Nitroglycerin facilitates calcitonin gene-related peptide-induced behavior.
    Neuroreport, 2008, Aug-27, Volume: 19, Issue:13

    Topics: Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Drug Interactions; Grooming; Injections, Intraperitoneal; Male; Nitroglycerin; Rats; Rats, Sprague-Dawley; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Sumatriptan; Vasodilator Agents

2008
Sumatriptan alleviates nitroglycerin-induced mechanical and thermal allodynia in mice.
    Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:2

    Topics: Animals; Brain; Cortical Spreading Depression; Gene Expression; Hot Temperature; Hyperalgesia; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Nitroglycerin; Physical Stimulation; Proto-Oncogene Proteins c-fos; Serotonin 5-HT1 Receptor Antagonists; Spinal Cord; Sumatriptan; Vasodilator Agents

2010
Headache in three new cases of Harlequin syndrome with accompanying pharmacological comparison with migraine.
    Journal of neurology, neurosurgery, and psychiatry, 2012, Volume: 83, Issue:6

    Topics: Adult; Aged; Autonomic Nervous System Diseases; Diagnosis, Differential; Dihydroergotamine; Ergotamine; Female; Flushing; Headache; Humans; Hypohidrosis; Middle Aged; Migraine Disorders; Nitroglycerin; Sumatriptan; Vasoconstrictor Agents; Vasodilator Agents

2012
Characterization of a novel model of chronic migraine.
    Pain, 2014, Volume: 155, Issue:2

    Topics: Animals; Chronic Disease; Disease Models, Animal; Female; Freund's Adjuvant; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Migraine Disorders; Nitroglycerin; Pain Measurement; Sumatriptan; Vasodilator Agents

2014
Role of Ser102 and Ser104 as regulators of cGMP hydrolysis by PDE5A.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Amino Acid Substitution; Calcitonin Gene-Related Peptide; Catalytic Domain; Cell Line; Cilostazol; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Humans; In Vitro Techniques; Models, Molecular; Nitroglycerin; Phosphodiesterase Inhibitors; Piperazines; Purines; Serine; Sildenafil Citrate; Sulfonamides; Sumatriptan; Tetrazoles

2014
ST-Elevation Myocardial Infarction After Sumitriptan Ingestion in Patient with Normal Coronary Arteries.
    The western journal of emergency medicine, 2015, Volume: 16, Issue:5

    Topics: Electrocardiography; Emergency Service, Hospital; Female; Humans; Middle Aged; Migraine Disorders; Myocardial Infarction; Nitroglycerin; Sumatriptan; Vasoconstrictor Agents; Vasodilator Agents

2015
The effects of acute and preventive migraine therapies in a mouse model of chronic migraine.
    Cephalalgia : an international journal of headache, 2016, Volume: 36, Issue:11

    Topics: Acute Disease; Amiloride; Animals; Anticonvulsants; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Migraine Disorders; Nitroglycerin; Pain Measurement; Propranolol; Serotonin 5-HT1 Receptor Agonists; Species Specificity; Sumatriptan; Treatment Outcome; Valproic Acid; Vasodilator Agents

2016
Mechanisms mediating nitroglycerin-induced delayed-onset hyperalgesia in the rat.
    Neuroscience, 2016, Mar-11, Volume: 317

    Topics: Animals; Disease Models, Animal; Endothelial Cells; Female; Hyperalgesia; Male; Mast Cells; Neutrophils; Nitroglycerin; Nociception; Octoxynol; p-Methoxy-N-methylphenethylamine; Pain Threshold; Phenols; Polycyclic Compounds; Purinergic P2X Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sex Factors; Sumatriptan; Surface-Active Agents; Time Factors; Vasoconstrictor Agents; Vasodilator Agents

2016
Clinically relevant behavioral endpoints in a recurrent nitroglycerin migraine model in rats.
    The journal of headache and pain, 2016, Volume: 17

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Male; Migraine Disorders; Motor Activity; Nitroglycerin; Photophobia; Rats; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Treatment Outcome; Vasodilator Agents

2016
Pharmacology of reflex blinks in the rat: a novel model for headache research.
    The journal of headache and pain, 2016, Volume: 17, Issue:1

    Topics: Animals; Blinking; Disease Models, Animal; Electromyography; Male; Migraine Disorders; Nitric Oxide Donors; Nitroglycerin; Rats; Rats, Sprague-Dawley; Reflex; Serotonin 5-HT1 Receptor Agonists; Sumatriptan

2016
Nitroglycerin enhances the propagation of cortical spreading depression: comparative studies with sumatriptan and novel kynurenic acid analogues.
    Drug design, development and therapy, 2017, Volume: 11

    Topics: Cortical Spreading Depression; Dose-Response Relationship, Drug; Humans; Injections, Intraperitoneal; Kynurenic Acid; Migraine Disorders; Nitroglycerin; Sumatriptan; Vasodilator Agents

2017
Soluble guanylyl cyclase is a critical regulator of migraine-associated pain.
    Cephalalgia : an international journal of headache, 2018, Volume: 38, Issue:8

    Topics: Adrenergic beta-Antagonists; Allosteric Regulation; Animals; Anticonvulsants; Calcitonin Gene-Related Peptide; Disease Models, Animal; Enzyme Inhibitors; Female; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Migraine Disorders; Molecular Targeted Therapy; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Oxadiazoles; Propranolol; Proto-Oncogene Proteins c-fos; Quinoxalines; Serotonin 5-HT1 Receptor Agonists; Soluble Guanylyl Cyclase; Sumatriptan; Topiramate

2018
The effect of intravenous administration of liposomal curcumin in addition to sumatriptan treatment in an experimental migraine model in rats.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Administration, Intravenous; Animals; Curcumin; Disease Models, Animal; Liposomes; Male; Malondialdehyde; Migraine Disorders; Nitric Oxide; Nitroglycerin; Oxidative Stress; Pain Measurement; Rats; Sumatriptan

2018
Delta opioid receptor agonists are effective for multiple types of headache disorders.
    Neuropharmacology, 2019, Volume: 148

    Topics: Animals; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Headache Disorders; Hyperalgesia; Male; Mice; Morphine; Nitroglycerin; Piperazines; Receptors, Opioid, delta; Sumatriptan

2019
Low-dose interleukin-2 reverses behavioral sensitization in multiple mouse models of headache disorders.
    Pain, 2020, Volume: 161, Issue:6

    Topics: Animals; Headache Disorders; Interleukin-2; Mice; Migraine Disorders; Nitroglycerin; Sumatriptan

2020
PACAP signaling is not involved in GTN- and levcromakalim-induced hypersensitivity in mouse models of migraine.
    The journal of headache and pain, 2022, Dec-05, Volume: 23, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Cromakalim; Disease Models, Animal; Drug Hypersensitivity; Mice; Migraine Disorders; Nitroglycerin; Pituitary Adenylate Cyclase-Activating Polypeptide; Signal Transduction; Sumatriptan

2022
Duality in response of intracranial vessels to nitroglycerin revealed in rats by imaging photoplethysmography.
    Scientific reports, 2023, 07-24, Volume: 13, Issue:1

    Topics: Animals; Migraine Disorders; Nitroglycerin; Photoplethysmography; Rats; Sumatriptan; Vasodilator Agents

2023
Quality by design for sumatriptan loaded nano-ethosomal mucoadhesive gel for the therapeutic management of nitroglycerin induced migraine.
    International journal of pharmaceutics, 2023, Nov-05, Volume: 646

    Topics: Administration, Intranasal; Humans; Migraine Disorders; Nasal Mucosa; Nitroglycerin; Sumatriptan

2023