Page last updated: 2024-08-16

sumatriptan and naratriptan

sumatriptan has been researched along with naratriptan in 77 studies

Research

Studies (77)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (20.78)18.2507
2000's48 (62.34)29.6817
2010's12 (15.58)24.3611
2020's1 (1.30)2.80

Authors

AuthorsStudies
Adham, N; Audia, JE; Kohlman, DT; Krushinski, J; Liang, SX; Schaus, JM; Walker, C; Xu, YC; Zgombick, JM1
Hopkins, B; McHarg, A; Melrose, H; Napier, C; Stewart, M; Wallis, R1
Audia, JE; Krushinski, JH; Lucaites, VL; Nelson, DL; Schaus, JM; Wainscott, DB; Zgombick, JM1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
David, M; Duléry, BD; Huebert, ND; Petty, MA; Schoun, J1
Beattie, DT; Connor, HE; Feniuk, W; Humphrey, PP; North, PC; Oxford, AW; Saynor, DA1
Audinot-Bouchez, V; Chaput, C; Conte, C; Lavielle, G; Lochon, S; Millan, MJ; Newman-Tancredi, A; Verrièle, L1
Goadsby, PJ2
Bonnafous, R; John, GW; Valentin, JP1
Bax, WA; Ferrari, MD; MaassenVanDenBrink, A; Reekers, M; Saxena, PR1
Scholz, MJ1
Monseu, G; Sternon, J1
Goldstein, D1
Dowson, A1
Deleu, D; Hanssens, Y1
Diener, HC; Limmroth, V1
Bartlett, MG; Stewart, JT; Vishwanathan, K1
Logemann, CD; Rankin, LM1
Bartleson, JD1
Becker, W; Boswell, D; Crisp, A; Göbel, H; Hauge, T; Mihout, B; Niewold, J; Tørring, J; Winter, P1
Tfelt-Hansen, P4
Weintraub, JR1
Potrebic, S; Raskin, NH1
Croft, P; Frischer, M; Goadsby, PJ; Millson, D1
Hashimoto, S; Iwata, M1
Cipolla, G; Crema, F; De Ponti, F; Frigo, G; Moro, E; Sacco, S1
Marcus, DA1
Zagami, AS1
Goadsby, PJ; Jiang, K; Lines, CR; Lipton, RB; Massiou, H; McCarroll, KA; Pascual, J; Vandormael, K1
Adelman, JU; Diener, HC; Ferrari, MD; Lines, CR; Lipton, RB; McCarroll, KA; Vandormael, K1
Welch, KM1
Connor, HE1
Cady, R1
Diener, HC; Fritsche, G; Katsarava, Z; Limmroth, V; Muessig, M1
Deprez, S; Einer-Jensen, N; Larsen, L; Schwartz, S; Starns, E1
Freitag, FG1
Fité, B; López-Gil, A; Pascual, J1
Akin, D; Gurdal, H; Onaran, HO1
Rapoport, AM; Sheftell, FD; Tepper, SJ1
Bussone, G; D'Amico, D; Gerth, W; Lines, CR; McCarroll, KA1
Adelman, JU; Lewit, EJ1
Allen, C; Evans, DC; Evers, R; Hargreaves, R; Lake, BG; O'Connor, D1
John, GW; Létienne, R; Verscheure, Y1
Ashcroft, DM; Millson, D1
Iizuka, T; Sakai, F1
Jähnichen, S; Pertz, HH; Radtke, OA1
Austin, R; Barrows, C; Mansbach, H; Putnam, G; Saunders, W1
Kowa, H; Nakashima, K; Takeshima, T1
Morillo, LE2
Muñoz, P; Pascual, J1
Edvinsson, L; Ingemansson, R; Jarvius, M; Malmsjö, M; Wackenfors, A1
Aarons, L; Gueorguieva, I; Nestorov, IA; Rowland, M1
Auvin, S; Cuvellier, JC; Joriot, S; Vallée, L1
Danhof, M; Della Pasqua, O; Maas, HJ1
Fontes Ribeiro, CA; Marques, FB; Silva, SA1
Steiner, TJ; Tfelt-Hansen, P1
Autret-Leca, E; Beau-Salinas, F; Bensouda-Grimaldi, L; Cissoko, H; Jonville-Béra, AP1
Bozzo, P; Duong, S; Einarson, A; Nordeng, H1
Baxi, GA; Mishra, T; Patel, C; Patel, M; Shrivastav, PS; Singhal, P; Yadav, M1
Goadsby, PJ; Kavantzas, N; Knight, YE; Lasalandra, M; Mitsikostas, DD1
Derry, S; Law, S; Moore, RA1
Pickholz, M; Wood, I1
Diener, HC1
Kitagawa, Y; Suzuki, Y; Takayanagi, R; Tokuoka, K; Watanabe, M; Yamada, Y1
Bollinger, L; Cangialose, C; Chia, V; Mikol, DD; Xue, F; Yusuf, A1

Reviews

24 review(s) available for sumatriptan and naratriptan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Profiles of 5-HT 1B/1D agonists in acute migraine with special reference to second generation agents.
    Acta neurologica Belgica, 1999, Volume: 99, Issue:2

    Topics: Acute Disease; Animals; Clinical Trials as Topic; Coronary Circulation; Coronary Vasospasm; Drug Design; Drug Interactions; Humans; Inactivation, Metabolic; Indoles; Meninges; Migraine Disorders; Molecular Structure; Nociceptors; Oxazoles; Oxazolidinones; Piperidines; Propranolol; Pyrrolidines; Randomized Controlled Trials as Topic; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Recurrence; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines; Vasoconstrictor Agents

1999
Acute management of migraine: triptans and beyond.
    Current opinion in neurology, 1999, Volume: 12, Issue:3

    Topics: Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines

1999
The scientific basis of medication choice in symptomatic migraine treatment.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1999, Volume: 26 Suppl 3

    Topics: Acute Disease; Choice Behavior; Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disorders; Models, Biological; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Severity of Illness Index; Sumatriptan; Triazoles; Tryptamines

1999
Newer intranasal migraine medications.
    American family physician, 2000, Jan-01, Volume: 61, Issue:1

    Topics: Administration, Intranasal; Administration, Oral; Analgesics, Non-Narcotic; Clinical Trials as Topic; Dihydroergotamine; Half-Life; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines

2000
Treatment of acute migraine attacks.
    The Journal of the American Osteopathic Association, 2000, Volume: 100, Issue:9 Suppl

    Topics: Analgesics; Ergotamine; Humans; Indoles; Migraine Disorders; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents

2000
New abortive agents for the treatment of migraine.
    Advances in internal medicine, 2001, Volume: 46

    Topics: Clinical Trials as Topic; Female; Humans; Indoles; Male; Migraine Disorders; Oxazolidinones; Piperidines; Prognosis; Recurrence; Serotonin Receptor Agonists; Severity of Illness Index; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines

2001
[Current topics: expectation for new triptans].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2001, Apr-10, Volume: 90, Issue:4

    Topics: Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines

2001
Gastric motor effects of triptans: open questions and future perspectives.
    Pharmacological research, 2001, Volume: 43, Issue:3

    Topics: Forecasting; Gastrointestinal Motility; Humans; Indoles; Nausea; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vomiting

2001
Establishing a standard of speed for assessing the efficacy of the serotonin(1B/1D) agonists (triptans).
    Archives of neurology, 2001, Volume: 58, Issue:7

    Topics: Analgesics, Non-Narcotic; Carbazoles; Clinical Trials as Topic; Humans; Indoles; Migraine Disorders; Oxazolidinones; Pain Measurement; Patient Satisfaction; Piperidines; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Treatment Outcome; Triazoles; Tryptamines

2001
Have the triptans fulfilled their promise?
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2001, Volume: 8, Issue:5

    Topics: Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines

2001
Comparison of rizatriptan and other triptans on stringent measures of efficacy.
    Neurology, 2001, Oct-23, Volume: 57, Issue:8

    Topics: Administration, Oral; Humans; Indoles; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Piperidines; Randomized Controlled Trials as Topic; Retrospective Studies; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines

2001
Acute treatment of migraine and the role of triptans.
    Current neurology and neuroscience reports, 2001, Volume: 1, Issue:2

    Topics: Acute Disease; Blood Flow Velocity; Carbazoles; Clinical Trials as Topic; Drug Administration Routes; Female; Humans; Indoles; Male; Menstruation; Migraine Disorders; Oxazolidinones; Piperidines; Practice Guidelines as Topic; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines; Vasoconstriction; Vasoconstrictor Agents

2001
Mechanisms of action of the 5-HT1B/1D receptor agonists.
    Archives of neurology, 2002, Volume: 59, Issue:7

    Topics: Carbazoles; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines

2002
Comparative aspects of triptans in treating migraine.
    Clinical cornerstone, 2001, Volume: 4, Issue:3

    Topics: Carbazoles; Cardiovascular Diseases; Humans; Indoles; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Piperidines; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines

2001
Naratriptan for the treatment of acute migraine: meta-analysis of randomised controlled trials.
    Pharmacoepidemiology and drug safety, 2004, Volume: 13, Issue:2

    Topics: Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines

2004
[Recent progress in therapy for migraine headache].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2004, Feb-10, Volume: 93, Issue:2

    Topics: Anticonvulsants; Botulinum Toxins; Calcitonin Gene-Related Peptide; Central Nervous System; Clinical Trials as Topic; Drug Design; Fructose; Humans; Indoles; Meta-Analysis as Topic; Migraine Disorders; Pain; Piperidines; Pyrrolidines; Serotonin Receptor Agonists; Signal Transduction; Sumatriptan; Topiramate; Triazoles; Trigeminal Nerve; Tryptamines; Vasodilation

2004
[Meta-analysis of triptan treatment in migraine].
    No to shinkei = Brain and nerve, 2004, Volume: 56, Issue:9

    Topics: Carbazoles; Evidence-Based Medicine; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1D; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines

2004
Migraine headache.
    Clinical evidence, 2003, Issue:10

    Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Diclofenac; Drug Therapy, Combination; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines

2003
Migraine headache.
    Clinical evidence, 2004, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Sumatriptan; Triazoles; Tryptamines

2004
Over-the-counter triptans for migraine : what are the implications?
    CNS drugs, 2007, Volume: 21, Issue:11

    Topics: Germany; Humans; Migraine Disorders; Nonprescription Drugs; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines; United Kingdom

2007
Parenteral vs. oral sumatriptan and naratriptan: plasma levels and efficacy in migraine. a comment.
    The journal of headache and pain, 2007, Volume: 8, Issue:5

    Topics: Administration, Oral; Biological Availability; Humans; Infusions, Parenteral; Injections, Subcutaneous; Migraine Disorders; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Treatment Outcome; Tryptamines

2007
Naproxen with or without an antiemetic for acute migraine headaches in adults.
    The Cochrane database of systematic reviews, 2013, Oct-20, Issue:10

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Drug Therapy, Combination; Humans; Migraine Disorders; Naproxen; Nausea; Piperidines; Randomized Controlled Trials as Topic; Sumatriptan; Tryptamines; Vomiting

2013
Naratriptan is as effective as sumatriptan for the treatment of migraine attacks when used properly. A mini-review.
    Cephalalgia : an international journal of headache, 2021, Volume: 41, Issue:14

    Topics: Animals; Migraine Disorders; Piperidines; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Tryptamines

2021

Trials

3 trial(s) available for sumatriptan and naratriptan

ArticleYear
Comparison of naratriptan and sumatriptan in recurrence-prone migraine patients. Naratriptan International Recurrence Study Group.
    Clinical therapeutics, 2000, Volume: 22, Issue:8

    Topics: Adolescent; Adult; Aged; Cross-Over Studies; Double-Blind Method; Female; Humans; Indoles; Middle Aged; Migraine Disorders; Piperidines; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents

2000
Clinical features of withdrawal headache following overuse of triptans and other headache drugs.
    Neurology, 2001, Nov-13, Volume: 57, Issue:9

    Topics: Adult; Analgesics; Drug Therapy, Combination; Ergotamine; Female; Headache; Humans; Indoles; Male; Middle Aged; Oxazolidinones; Piperidines; Prospective Studies; Substance Withdrawal Syndrome; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents

2001
Theory-based analysis of clinical efficacy of triptans using receptor occupancy.
    The journal of headache and pain, 2014, Dec-08, Volume: 15

    Topics: Humans; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines

2014

Other Studies

50 other study(ies) available for sumatriptan and naratriptan

ArticleYear
N-Methyl-5-tert-butyltryptamine: A novel, highly potent 5-HT1D receptor agonist.
    Journal of medicinal chemistry, 1999, Feb-11, Volume: 42, Issue:3

    Topics: Cell Line; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Radioligand Assay; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship; Tryptamines

1999
Characterisation of the 5-HT receptor binding profile of eletriptan and kinetics of [3H]eletriptan binding at human 5-HT1B and 5-HT1D receptors.
    European journal of pharmacology, 1999, Mar-05, Volume: 368, Issue:2-3

    Topics: Animals; Binding, Competitive; Cell Line; Cold Temperature; COS Cells; HeLa Cells; Humans; Indoles; Kinetics; Oxazoles; Oxazolidinones; Piperidines; Pyrrolidines; Radioligand Assay; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Sumatriptan; Triazoles; Tritium; Tryptamines

1999
[3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties.
    Naunyn-Schmiedeberg's archives of pharmacology, 2005, Volume: 371, Issue:3

    Topics: Animals; Benzamides; Brain; Cells, Cultured; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Humans; In Vitro Techniques; Indoles; Ligands; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT1F; Receptors, Serotonin; Serotonin Receptor Agonists; Transfection; Tritium

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
A method using a liquid chromatographic-electrospray-mass spectrometric assay for the determination of antimigraine compounds: preliminary pharmacokinetics of MDL 74,721, sumatriptan and naratriptan, in rabbit.
    Journal of pharmaceutical and biomedical analysis, 1997, Volume: 15, Issue:7

    Topics: Administration, Oral; Animals; Chromatography, Liquid; Indoles; Injections, Intravenous; Male; Mass Spectrometry; Piperidines; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Serotonin Receptor Agonists; Sulfonamides; Sumatriptan; Tetrahydronaphthalenes; Tryptamines; Vasoconstrictor Agents

1997
Naratriptan: biological profile in animal models relevant to migraine.
    Cephalalgia : an international journal of headache, 1997, Volume: 17, Issue:3

    Topics: Animals; Basilar Artery; Cerebrovascular Circulation; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Female; Humans; Indoles; Male; Mice; Muscle Contraction; Piperidines; Rats; Sumatriptan; Tryptamines

1997
Agonist activity of antimigraine drugs at recombinant human 5-HT1A receptors: potential implications for prophylactic and acute therapy.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Binding, Competitive; Cell Membrane; Cricetinae; Dihydroergotamine; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Humans; In Vitro Techniques; Indoles; Lisuride; Methysergide; Migraine Disorders; Piperazines; Piperidines; Pizotyline; Propranolol; Propylamines; Protein Binding; Pyridines; Pyrimidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tryptamines

1997
A triptan too far?
    Journal of neurology, neurosurgery, and psychiatry, 1998, Volume: 64, Issue:2

    Topics: Acute Disease; Clinical Trials as Topic; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines

1998
Contractile responses evoked by dihydroergotamine, naratriptan and sumatriptan in the canine isolated coronary artery.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:2

    Topics: Animals; Coronary Vessels; Dihydroergotamine; Dogs; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents

1998
Coronary side-effect potential of current and prospective antimigraine drugs.
    Circulation, 1998, Jul-07, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Angina Pectoris; Child; Coronary Vessels; Dihydroergotamine; Ergotamine; Female; Humans; In Vitro Techniques; Indoles; Male; Methysergide; Middle Aged; Migraine Disorders; Piperidines; Sulfonamides; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents

1998
When the migraine rx isn't working.
    RN, 1998, Volume: 61, Issue:8

    Topics: Administration, Oral; Adult; Contraindications; Female; Humans; Indoles; Migraine Disorders; Patient Selection; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Tryptamines

1998
New "triptans" and other drugs for migraine.
    The Medical letter on drugs and therapeutics, 1998, Oct-09, Volume: 40, Issue:1037

    Topics: Adrenergic beta-Antagonists; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Dihydroergotamine; Drug Interactions; Ergotamine; Humans; Indoles; Methysergide; Migraine Disorders; Naproxen; Oxazoles; Oxazolidinones; Piperidines; Propranolol; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Timolol; Triazoles; Tryptamines; Valproic Acid; Vasoconstrictor Agents

1998
[Zolmitriptan].
    Revue medicale de Bruxelles, 1998, Volume: 19, Issue:6

    Topics: Chemistry, Pharmaceutical; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines

1998
Vasoconstrictive properties of the 5HT1B/1D agonists: response to Dahlöf and Mathew.
    Cephalalgia : an international journal of headache, 1999, Volume: 19, Issue:5

    Topics: Humans; Indoles; Migraine Disorders; Piperidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Risk Factors; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents

1999
Drug-induced headaches.
    Lancet (London, England), 1999, Jul-17, Volume: 354, Issue:9174

    Topics: Analgesics, Non-Narcotic; Ergotamine; Headache; Humans; Indoles; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines

1999
Determination of antimigraine compounds rizatriptan, zolmitriptan, naratriptan and sumatriptan in human serum by liquid chromatography/electrospray tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2000, Volume: 14, Issue:3

    Topics: Bufotenin; Chromatography, High Pressure Liquid; Humans; Indoles; Mass Spectrometry; Migraine Disorders; Molecular Structure; Oxazoles; Oxazolidinones; Piperidines; Sensitivity and Specificity; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents

2000
Triptans to the rescue: effective therapy for migraine headaches in the workplace.
    Mayo Clinic proceedings, 2000, Volume: 75, Issue:8

    Topics: Absenteeism; Adult; Cost-Benefit Analysis; Efficiency; Female; Humans; Indoles; Injections, Subcutaneous; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Self Administration; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines; Workplace

2000
A comment on time-to-event analysis for headache relief.
    Cephalalgia : an international journal of headache, 2000, Volume: 20, Issue:4

    Topics: Analgesics; Headache; Humans; Indoles; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Triazoles; Tryptamines

2000
Are triptans with enhanced lipophilicity used for the acute treatment of migraine associated with an increased consulting rate for depressive illness?
    Cephalalgia : an international journal of headache, 2000, Volume: 20, Issue:8

    Topics: Cohort Studies; Depression; Female; Humans; Indoles; Male; Migraine Disorders; Oxazolidinones; Piperidines; Referral and Consultation; Regression Analysis; Serotonin Receptor Agonists; Sumatriptan; Tryptamines

2000
Effect of rizatriptan and other triptans on the nausea symptom of migraine: a post hoc analysis.
    Headache, 2001, Volume: 41, Issue:8

    Topics: Administration, Oral; Adult; Double-Blind Method; Humans; Indoles; Migraine Disorders; Nausea; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents

2001
Sumatriptan and naratriptan tolerability and safety: an update of post-marketing experience.
    Cephalalgia : an international journal of headache, 2001, Volume: 21 Suppl 1

    Topics: Contraindications; Coronary Circulation; Dose-Response Relationship, Drug; Humans; Indoles; Injections, Subcutaneous; Migraine Disorders; Piperidines; Product Surveillance, Postmarketing; Risk Factors; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents

2001
Building on the sumatriptan experience: the development of naratriptan.
    Cephalalgia : an international journal of headache, 2001, Volume: 21 Suppl 1

    Topics: Administration, Oral; Biological Availability; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disorders; Piperidines; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Treatment Outcome; Tryptamines; Vasoconstrictor Agents

2001
Looking forward: the expanding utility of sumatriptan and naratriptan.
    Cephalalgia : an international journal of headache, 2001, Volume: 21 Suppl 1

    Topics: Headache Disorders; Humans; Indoles; Migraine Disorders; Piperidines; Primary Health Care; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines; Vasoconstrictor Agents

2001
Intranasal absorption of sumatriptan and naratriptan: no evidence of local transfer from the nasal cavities to the brain arterial blood in male rats.
    Biopharmaceutics & drug disposition, 2001, Volume: 22, Issue:5

    Topics: Absorption; Animals; Cerebral Arteries; Indoles; Male; Nasal Cavity; Piperidines; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Sumatriptan; Tryptamines

2001
Comparison of triptan tablet consumption per attack: a prospective study of migraineurs in Spain.
    Headache, 2002, Volume: 42, Issue:2

    Topics: Female; Humans; Indoles; Male; Migraine Disorders; Oxazolidinones; Piperidines; Prospective Studies; Serotonin Receptor Agonists; Sumatriptan; Tablets; Triazoles; Tryptamines

2002
Agonist-directed trafficking explaining the difference between response pattern of naratriptan and sumatriptan in rabbit common carotid artery.
    British journal of pharmacology, 2002, Volume: 136, Issue:2

    Topics: Animals; Carotid Artery, Common; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Indoles; Piperidines; Protein Transport; Rabbits; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstriction

2002
Restoring migraine sufferers' ability to function normally: a comparison of rizatriptan and other triptans in randomized trials.
    European neurology, 2002, Volume: 48, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Female; Humans; Indoles; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Retrospective Studies; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines

2002
Eletriptan metabolism by human hepatic CYP450 enzymes and transport by human P-glycoprotein.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:7

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Genes, MDR; Humans; Indoles; Injections, Intravenous; Male; Mice; Mice, Mutant Strains; Miconazole; Microsomes, Liver; Oxazolidinones; Oxidoreductases, N-Demethylating; Phenotype; Piperidines; Pyrrolidines; Recombinant Proteins; Statistics as Topic; Sumatriptan; Triazoles; Troleandomycin; Tryptamines

2003
Investigation of the effects of naratriptan, rizatriptan, and sumatriptan on jugular venous oxygen saturation in anesthetized pigs: implications for their mechanism of acute antimigraine action.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:1

    Topics: Anesthesia; Animals; Blood Gas Analysis; Hemodynamics; Indoles; Jugular Veins; Male; Migraine Disorders; Oxygen; Piperidines; Sumatriptan; Swine; Triazoles; Tryptamines; Vasoconstriction; Vasoconstrictor Agents

2003
[Improved pharmacokinetics. Fast tryptan with sustained response].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Administration, Oral; Controlled Clinical Trials as Topic; Delayed-Action Preparations; Female; Headache; Humans; Indoles; Male; Migraine Disorders; Oxazolidinones; Piperidines; Placebos; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Tryptamines

2003
[Highly selective beginning. Associated symptoms and side effects in retrospect].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines

2003
Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:1

    Topics: Animals; Benzamides; Brain; Carbazoles; Dinoprost; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelium, Vascular; Female; Forecasting; Guinea Pigs; Iliac Artery; Indoles; Ketanserin; Male; Muscle Contraction; Muscle, Smooth; Oxadiazoles; Oxazolidinones; Piperazines; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Sumatriptan; Triazoles; Tryptamines

2004
The sumatriptan/naratriptan aggregated patient (SNAP) database: aggregation, validation and application.
    Cephalalgia : an international journal of headache, 2004, Volume: 24, Issue:7

    Topics: Clinical Trials as Topic; Data Collection; Databases, Factual; Humans; Indoles; Logistic Models; Migraine Disorders; Piperidines; Sumatriptan; Tryptamines

2004
Correlation between lipophilicity and triptan outcomes.
    Headache, 2005, Volume: 45, Issue:1

    Topics: Central Nervous System Diseases; Chemical Phenomena; Chemistry, Physical; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Statistics as Topic; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines

2005
Triptans induce vasoconstriction of human arteries and veins from the thoracic wall.
    Journal of cardiovascular pharmacology, 2005, Volume: 45, Issue:5

    Topics: Aged; Aged, 80 and over; Arteries; Dose-Response Relationship, Drug; Female; Humans; Indoles; Male; Middle Aged; Oxazolidinones; Piperidines; Polymerase Chain Reaction; Serotonin Receptor Agonists; Sumatriptan; Thorax; Triazoles; Tryptamines; Vasoconstriction; Veins

2005
Uncertainty analysis in pharmacokinetics and pharmacodynamics: application to naratriptan.
    Pharmaceutical research, 2005, Volume: 22, Issue:10

    Topics: Algorithms; Analgesics; Female; Humans; Male; Migraine Disorders; Models, Biological; Piperidines; Serotonin Receptor Agonists; Software; Sumatriptan; Tryptamines; Vasoconstrictor Agents

2005
[Medical treatment of migraine attacks in the child].
    Revue de l'infirmiere, 2006, Issue:117

    Topics: Acetaminophen; Age Factors; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Ergot Alkaloids; Humans; Ibuprofen; Life Style; Migraine Disorders; Oxazolidinones; Parents; Patient Education as Topic; Pediatrics; Piperidines; Pyrrolidines; Risk Factors; Serotonin Receptor Agonists; Sumatriptan; Taste Disorders; Triazoles; Tryptamines; Vasoconstrictor Agents

2006
A model-based approach to treatment comparison in acute migraine.
    British journal of clinical pharmacology, 2006, Volume: 62, Issue:5

    Topics: Dose-Response Relationship, Drug; Humans; Markov Chains; Migraine Disorders; Models, Biological; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines

2006
Characterization of the human basilar artery contractile response to 5-HT and triptans.
    Fundamental & clinical pharmacology, 2007, Volume: 21, Issue:3

    Topics: Basilar Artery; Female; Humans; In Vitro Techniques; Male; Middle Aged; Oxazolidinones; Piperidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstriction; Vasoconstrictor Agents

2007
Maximum effect of triptans in migraine? A comment.
    Cephalalgia : an international journal of headache, 2008, Volume: 28, Issue:7

    Topics: Dose-Response Relationship, Drug; Humans; Injections, Subcutaneous; Migraine Disorders; Pain Measurement; Piperidines; Randomized Controlled Trials as Topic; Sumatriptan; Treatment Outcome; Tryptamines

2008
Drug dependence associated with triptans and ergot derivatives: a case/non-case study.
    European journal of clinical pharmacology, 2010, Volume: 66, Issue:4

    Topics: Claviceps; Dihydroergotamine; Ergotamine; Humans; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Risk; Substance-Related Disorders; Sumatriptan; Tryptamines

2010
Safety of triptans for migraine headaches during pregnancy and breastfeeding.
    Canadian family physician Medecin de famille canadien, 2010, Volume: 56, Issue:6

    Topics: Breast Feeding; Female; Humans; Migraine Disorders; Piperidines; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Risk Factors; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Tryptamines

2010
Development and validation of a sensitive and rapid method to determine naratriptan in human plasma by LC-ESI-MS-MS: application to a bioequivalence study.
    Journal of chromatographic science, 2011, Volume: 49, Issue:2

    Topics: Adult; Area Under Curve; Chromatography, Liquid; Drug Stability; Humans; Piperidines; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Sumatriptan; Tandem Mass Spectrometry; Therapeutic Equivalency; Tryptamines

2011
Triptans attenuate capsaicin-induced CREB phosphorylation within the trigeminal nucleus caudalis: a mechanism to prevent central sensitization?
    The journal of headache and pain, 2011, Volume: 12, Issue:4

    Topics: Animals; Capsaicin; Cyclic AMP Response Element-Binding Protein; Hyperalgesia; Immunohistochemistry; Male; Pain; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Sensory System Agents; Sumatriptan; Trigeminal Caudal Nucleus; Tryptamines

2011
Triptan partition in model membranes.
    Journal of molecular modeling, 2014, Volume: 20, Issue:10

    Topics: Drug Stability; Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Structure; Phosphatidylcholines; Piperidines; Protons; Solubility; Structure-Activity Relationship; Sumatriptan; Tryptamines; Water

2014
[Pregnant women can take triptans].
    MMW Fortschritte der Medizin, 2014, Oct-23, Volume: 156, Issue:18

    Topics: Congenital Abnormalities; Female; Humans; Naproxen; Piperidines; Pregnancy; Sumatriptan; Tryptamines

2014
Use of existing electronic health care databases to evaluate medication safety in pregnancy: Triptan exposure in pregnancy as a case study.
    Pharmacoepidemiology and drug safety, 2018, Volume: 27, Issue:12

    Topics: Abnormalities, Drug-Induced; Administrative Claims, Healthcare; Adolescent; Adult; Databases, Factual; Drug Combinations; Electronic Health Records; Female; Humans; Infant, Newborn; Migraine Disorders; Naproxen; Piperidines; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Registries; Retrospective Studies; Sumatriptan; Tryptamines; United States; Young Adult

2018