Page last updated: 2024-08-16

sumatriptan and indomethacin

sumatriptan has been researched along with indomethacin in 32 studies

Research

Studies (32)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (15.63)	18.2507
2000's	13 (40.63)	29.6817
2010's	13 (40.63)	24.3611
2020's	1 (3.13)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chang, G; Mathialagan, S; Ryu, S; Varma, MVS; Woody, N	1
Aguilera, JM; Alberca, R; Arenas, C; Casado, JL; López, JM; Moreno, A; Serrano, V	1
Hannerz, J; Jogestrand, T	1
Morales Asín, F	1
Antonaci, F; Caminero, AB; Pareja, JA; Sjaastad, O	1
Buckingham, JC; Kennard, C; Rhodes, KF	1
Aloisio, A; Del Bianco, P; Di Monda, V; Fonzari, M; Grazioli, I; Nicolodi, M; Sicuteri, F; Uslenghi, C; Vecchiet, L	1
Lisotto, C; Maggioni, F; Mainardi, F; Zanchin, G	1
Galeotti, N; Ghelardini, C; Grazioli, I; Uslenghi, C	1
Andrews, PL; Cheng, FH; Moreaux, B; Ngan, MP; Rudd, JA; Sam, TS; Wai, MK; Wan, C	1
Cerbo, R; Del Bene, E; Ferrari, A; Genco, S; Grazioli, I; Martelletti, P; Nappi, G; Pinessi, L; Sandrini, G; Sarchielli, P; Tamburro, P; Uslenghi, C; Zanchin, G	1
Rosenberg-Nordmann, M; Sprenger, T; Tölle, TR	1
Cohen, AS; Goadsby, PJ	1
Galeotti, N; Ghelardini, C; Grazioli, I; Uslenghi, C; Vivoli, E	1
Keller, DL	1
Benoliel, R; Eliav, E	1
Jansen-Olesen, I; Olesen, J; Tfelt-Hansen, P	1

Reviews

6 review(s) available for sumatriptan and indomethacin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Chronic paroxysmal hemicrania]. Neurologia (Barcelona, Spain), 1997, Volume: 12 Suppl 5 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diagnosis, Differential; Female; Headache; Humans; Indomethacin; Male; Sumatriptan; Vasoconstrictor Agents	1997
[Trigeminal autonomic cephalgias: diagnostic and therapeutic implications]. MMW Fortschritte der Medizin, 2007, Sep-06, Volume: 149, Issue:35-36 Topics: Administration, Intranasal; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Cluster Headache; Diagnosis, Differential; Humans; Indomethacin; Injections, Subcutaneous; Magnetic Resonance Imaging; Oxazolidinones; Paroxysmal Hemicrania; Serotonin Receptor Agonists; Sumatriptan; SUNCT Syndrome; Time Factors; Trigeminal Autonomic Cephalalgias; Tryptamines; Vasodilator Agents; Verapamil	2007
[Pathophysiology and treatment of trigeminal autonomic cephalalgias]. Schmerz (Berlin, Germany), 2008, Volume: 22 Suppl 1 Topics: Administration, Oral; Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cluster Headache; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Lamotrigine; Lidocaine; Male; Methysergide; Nociceptors; Oxygen Inhalation Therapy; Paroxysmal Hemicrania; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; SUNCT Syndrome; Topiramate; Triazines; Trigeminal Autonomic Cephalalgias; Trigeminal Nerve; Vasoconstrictor Agents; Vasodilator Agents; Verapamil	2008
Primary headache disorders. Dental clinics of North America, 2013, Volume: 57, Issue:3 Topics: Acetaminophen; Analgesics, Non-Narcotic; Anticonvulsants; Chronic Disease; Cluster Headache; Cyclooxygenase Inhibitors; Diagnosis, Differential; Headache Disorders, Primary; Humans; Indomethacin; Lamotrigine; Migraine Disorders; Paroxysmal Hemicrania; Sumatriptan; SUNCT Syndrome; Tension-Type Headache; Triazines; Trigeminal Autonomic Cephalalgias; Vasoconstrictor Agents	2013
Animal migraine models for drug development: status and future perspectives. CNS drugs, 2013, Volume: 27, Issue:12 Topics: Animals; Animals, Genetically Modified; Disease Models, Animal; Drug Discovery; Forecasting; Humans; Indomethacin; Migraine Disorders; Sumatriptan	2013

Trials

2 trial(s) available for sumatriptan and indomethacin

Article	Year
Efficacy of a fixed combination of indomethacin, prochlorperazine, and caffeine versus sumatriptan in acute treatment of multiple migraine attacks: a multicenter, randomized, crossover trial. Headache, 2003, Volume: 43, Issue:8 Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Drug Combinations; Female; Humans; Indomethacin; Male; Migraine Disorders; Prochlorperazine; Recurrence; Research Design; Serotonin Receptor Agonists; Sumatriptan; Suppositories; Treatment Outcome	2003
Efficacy of dosing and re-dosing of two oral fixed combinations of indomethacin, prochlorperazine and caffeine compared with oral sumatriptan in the acute treatment of multiple migraine attacks: a double-blind, double-dummy, randomised, parallel group, mu International journal of clinical practice, 2007, Volume: 61, Issue:8 Topics: Administration, Oral; Adolescent; Adult; Analgesics; Caffeine; Double-Blind Method; Drug Combinations; Female; Humans; Indomethacin; Male; Middle Aged; Migraine Disorders; Prochlorperazine; Recurrence; Sumatriptan; Treatment Outcome	2007

Article

Year

Efficacy of a fixed combination of indomethacin, prochlorperazine, and caffeine versus sumatriptan in acute treatment of multiple migraine attacks: a multicenter, randomized, crossover trial.

Headache, 2003, Volume: 43, Issue:8

Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Drug Combinations; Female; Humans; Indomethacin; Male; Migraine Disorders; Prochlorperazine; Recurrence; Research Design; Serotonin Receptor Agonists; Sumatriptan; Suppositories; Treatment Outcome

2003

Efficacy of dosing and re-dosing of two oral fixed combinations of indomethacin, prochlorperazine and caffeine compared with oral sumatriptan in the acute treatment of multiple migraine attacks: a double-blind, double-dummy, randomised, parallel group, mu

International journal of clinical practice, 2007, Volume: 61, Issue:8

Topics: Administration, Oral; Adolescent; Adult; Analgesics; Caffeine; Double-Blind Method; Drug Combinations; Female; Humans; Indomethacin; Male; Middle Aged; Migraine Disorders; Prochlorperazine; Recurrence; Sumatriptan; Treatment Outcome

2007

Other Studies

24 other study(ies) available for sumatriptan and indomethacin

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Identification of Organic Anion Transporter 2 Inhibitors: Screening, Structure-Based Analysis, and Clinical Drug Interaction Risk Assessment. Journal of medicinal chemistry, 2022, 11-10, Volume: 65, Issue:21 Topics: Drug Interactions; HEK293 Cells; Humans; Liver; Organic Anion Transporters, Sodium-Independent; Risk Assessment	2022
[Chronic cluster headache: course and outcome of treatment]. Neurologia (Barcelona, Spain), 1994, Volume: 9, Issue:9 Topics: Adrenal Cortex Hormones; Calcium Channel Blockers; Cluster Headache; Ergotamine; Humans; Indomethacin; Lithium Carbonate; Oxygen; Sumatriptan; Treatment Outcome; Trigeminal Ganglion	1994
Intracranial hypertension and sumatriptan efficacy in a case of chronic paroxysmal hemicrania which became bilateral. (The mechanism of indomethacin in CPH). Headache, 1993, Volume: 33, Issue:6 Topics: Adult; Brain; Female; Functional Laterality; Humans; Indoles; Indomethacin; Intracranial Pressure; Magnetic Resonance Imaging; Migraine Disorders; Sulfonamides; Sumatriptan; Vasoconstrictor Agents	1993
Chronic paroxysmal hemicrania and hemicrania continua: lack of efficacy of sumatriptan. Headache, 1998, Volume: 38, Issue:3 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dosage Forms; Female; Headache; Humans; Indomethacin; Male; Middle Aged; Serotonin Receptor Agonists; Sumatriptan	1998
The inhibition of nicotine-evoked relaxation of the guinea-pig isolated basilar artery by some analgesic drugs and progesterone. British journal of pharmacology, 1999, Volume: 126, Issue:4 Topics: Analgesics; Animals; Aspirin; Basilar Artery; Capsaicin; Dinoprost; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Migraine Disorders; NG-Nitroarginine Methyl Ester; Nicotine; Progesterone; Substance P; Sumatriptan; Vasodilation	1999
Hemicrania continua with contralateral episodic cluster headache: a case report. Cephalalgia : an international journal of headache, 2003, Volume: 23, Issue:9 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cluster Headache; Functional Laterality; Humans; Indomethacin; Male; Migraine Disorders; Serotonin Receptor Agonists; Sumatriptan; Vasodilator Agents; Verapamil	2003
Indomethacin, alone and combined with prochlorperazine and caffeine, but not sumatriptan, abolishes peripheral and central sensitization in in vivo models of migraine. The journal of pain, 2004, Volume: 5, Issue:8 Topics: Animals; Caffeine; Disease Models, Animal; Drug Therapy, Combination; Indomethacin; Male; Mice; Migraine Disorders; Pain Measurement; Peripheral Nerves; Prochlorperazine; Sumatriptan; Trigeminal Nerve	2004
Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew). European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3 Topics: Animals; Antiemetics; Butanols; Capsaicin; Cyclooxygenase Inhibitors; Dihydroergotamine; Diphenhydramine; Diterpenes; Domperidone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Indomethacin; Malates; Methysergide; Metoclopramide; Migraine Disorders; Ondansetron; Piperidines; Ruthenium Red; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Shrews; Sumatriptan; Time Factors; Tropanes; Vomiting	2005
The central analgesia induced by antimigraine drugs is independent from Gi proteins: superiority of a fixed combination of indomethacin, prochlorperazine and caffeine, compared to sumatriptan, in an in vivo model. The journal of headache and pain, 2009, Volume: 10, Issue:6 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Caffeine; Central Nervous System Stimulants; Cerebral Arteries; Disease Models, Animal; Dopamine Antagonists; Drug Combinations; Drug Evaluation, Preclinical; Drug Synergism; GTP-Binding Protein alpha Subunits, Gi-Go; Indomethacin; Male; Mice; Migraine Disorders; Prochlorperazine; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome	2009
Triptan therapy in migraine. The New England journal of medicine, 2010, 09-30, Volume: 363, Issue:14 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Indomethacin; Injections, Intravenous; Ketorolac; Migraine Disorders; Sumatriptan; United States; Vasoconstrictor Agents	2010