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sumatriptan and 1-(3-(5-(1,2,4-triazol-4-yl)-1h-indol-3-yl)propyl)-4-(2-(3-fluorophenyl)ethyl)piperazine

sumatriptan has been researched along with 1-(3-(5-(1,2,4-triazol-4-yl)-1h-indol-3-yl)propyl)-4-(2-(3-fluorophenyl)ethyl)piperazine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beer, MS; Jelley, RA; MacLeod, AM; Matassa, VG; Rathbone, D; Reeve, AJ; Stanton, JA; Sternfeld, F; Street, LJ; Watt, AP1
Beer, MS; Chambers, MS; Goodacre, S; Hobbs, SC; Hunt, P; Jelley, RA; MacLeod, AM; Matassa, VG; Rathbone, D; Reeve, AJ; Stanton, JA; Sternfeld, F; Street, LJ; Watt, AP1
Audinot, V; Millan, MJ; Moreira, C; Newman-Tancredi, A; Verrièle, L1
Choi, SK; Green, D; Ho, A; Klein, U; Marquess, D; Taylor, R; Turner, SD1
Hill, RG; Longmore, J; MacLeod, A; Maguire, JJ; Schofield, WN; Street, L1

Other Studies

5 other study(ies) available for sumatriptan and 1-(3-(5-(1,2,4-triazol-4-yl)-1h-indol-3-yl)propyl)-4-(2-(3-fluorophenyl)ethyl)piperazine

ArticleYear
Selective, orally active 5-HT1D receptor agonists as potential antimigraine agents.
    Journal of medicinal chemistry, 1997, Oct-24, Volume: 40, Issue:22

    Topics: Administration, Oral; Animals; Biological Availability; Migraine Disorders; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Species Specificity

1997
3-(Piperazinylpropyl)indoles: selective, orally bioavailable h5-HT1D receptor agonists as potential antimigraine agents.
    Journal of medicinal chemistry, 1999, Feb-25, Volume: 42, Issue:4

    Topics: Administration, Oral; Animals; Biological Availability; CHO Cells; Cricetinae; Indoles; Male; Migraine Disorders; Models, Molecular; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Recombinant Proteins; Serotonin Receptor Agonists; Structure-Activity Relationship

1999
Inverse agonism and constitutive activity as functional correlates of serotonin h5-HT(1B) receptor/G-protein stoichiometry.
    Molecular pharmacology, 2000, Volume: 58, Issue:5

    Topics: Animals; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ligands; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Antagonists; Sulfur Radioisotopes; Tritium

2000
Designing selective, high affinity ligands of 5-HT1D receptor by covalent dimerization of 5-HT1F ligands derived from 4-fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide.
    Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12

    Topics: Animals; Benzamides; CHO Cells; Cricetinae; Cricetulus; Dimerization; In Vitro Techniques; Indoles; Ligands; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Radioligand Assay; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT1F; Receptors, Serotonin; Saphenous Vein; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Structure-Activity Relationship

2008
Comparison of the vasoconstrictor effects of the selective 5-HT1D-receptor agonist L-775,606 with the mixed 5-HT1B/1D-receptor agonist sumatriptan and 5-HT in human isolated coronary artery.
    British journal of clinical pharmacology, 2000, Volume: 49, Issue:2

    Topics: Adult; Analysis of Variance; Coronary Vessels; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Indoles; Male; Middle Aged; Piperazines; Potassium Chloride; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Sumatriptan; Vasoconstriction

2000