sulprostone has been researched along with cinnamaldehyde* in 1 studies
1 other study(ies) available for sulprostone and cinnamaldehyde
| Article | Year |
|---|---|
[Effect of guizhi tang and its active components on the fever induced by EP3 agonist].
To investigate the effect of Guizhi Tang and its active components on the fever induced by EP3 receptor agonist sulprostone in rats.. The rise in body temperature evoked by a LCV(lateral cerebroventricle)-injection of sulprostone was compared with that of sulprostone induced-fever rats pretreated with Guizgi Tang and its active compounds, cinnamaldehyde, cinnamic acid and total glucosides of paeony.. Pretreatments with Guizhi Tang and cinnamaldehyde inhibited the rise in body temperature induced by sulprostone, while cinnamic acid tended to augment the fever. The sulprostone-induced fever was blocked by an ip pretreatment of total glucosides of paeony even below the basement.. Present data suggest that interruption with the down-stream events of EP3 receptor may contribute to the antipyretic action of Guizhi Tang, cinnamaldehyde and the total glucosides of paeony, while cinnamic acid may have no such effect. Topics: Acrolein; Analgesics, Non-Narcotic; Animals; Body Temperature; Cinnamates; Dinoprostone; Drug Combinations; Drugs, Chinese Herbal; Fever; Glucosides; Male; Paeonia; Plants, Medicinal; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype | 2003 |