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sulotroban and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid

sulotroban has been researched along with 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199021 (60.00)18.7374
1990's11 (31.43)18.2507
2000's2 (5.71)29.6817
2010's1 (2.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amerini, S; Ledda, F; Mantelli, L; Rubino, A1
Higo, K; Karasawa, A; Kubo, K; Shirakura, S1
Karasawa, A; Kubo, K; Shirakura, S1
Higo, K; Karasawa, A; Kawakage, M; Kubo, K; Obase, H; Ohshima, E; Shirakura, S1
Ezumi, K; Narisada, M; Yamakawa, M1
Beckerman, RC; Bellan, JA; Braquet, P; Dyson, MC; Kadowitz, PJ; McNamara, DB; Minkes, RK; Wegmann, MJ1
de Chaffoy de Courcelles, D; De Clerck, F1
Müller, B; Stürzebecher, S; Witt, W1
Stürzebecher, S; Witt, W1
Mest, HJ; Riedel, A; Schneider, S2
McGiff, JC; Nasjletti, A; Quilley, J1
Whittle, BJ1
Bolofo, ML; Giles, H; Kelly, MG; Leff, P; Robertson, AD1
Darius, H; Lefer, AM1
Patscheke, H; Witte, EC; Wolff, HP; Zehender, H1
Esplugues, JV; Whittle, BJ1
Hiller, E; Höfling, B; Riess, H; von Arnim, T1
Hamid-Bloomfield, S; Whittle, BJ1
Ceuppens, JL; Deckmyn, H; Vermylen, J; Vertessen, S1
Patscheke, H; Stegmeier, K2
McDonald, J; Smith, EF1
Daniel, JL; Morinelli, TA; Niewiarowski, S; Smith, JB1
Endele, R; Kaufmann, B; Neugebauer, G; Patscheke, H; Staiger, C; Stegmeier, K; Strein, K1
Müller-Beckmann, B; Neugebauer, G; Patscheke, H; Sponer, G; Staiger, C; Stegmeier, K1
Arnout, J; Deckmyn, H; Gresele, P; Janssens, W; Lemmens, J; Vermylen, J1
Müller-Beckmann, B; Patscheke, H; Pill, J; Schmidt, FH; Stegmeier, K; Witte, EC; Wolff, HP1
Brüne, B; Ullrich, V; von Appen, F1
Heptinstall, S; Lösche, W; Sanderson, HM; Vickers, J1
Dieter, JP; Komiotis, D; Le Breton, GC; Lim, CT; Wencel-Drake, JD1
Asai, F; Koike, H; Ogawa, T; Sugidachi, A1
Delarge, J; Dogné, JM; Masereel, B; Michaux, C; Rolin, S1
Fu, LW; Longhurst, JC; Phan, A1
Beitinger, F; Bilzer, M; Gerbes, AL; Göke, B; Gülberg, V; Härtl, JM; Steib, CJ1

Trials

2 trial(s) available for sulotroban and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid

ArticleYear
Thromboxane receptor blockade versus cyclooxigenase inhibition: antiplatelet effects in patients.
    Thrombosis research, 1986, Apr-15, Volume: 42, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angioplasty, Balloon; Arteriosclerosis; Aspirin; Bleeding Time; Blood Platelets; Clinical Trials as Topic; Collagen; Cyclooxygenase Inhibitors; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane B2; Thromboxanes

1986
BM 13.177, a selective blocker of platelet and vessel wall thromboxane receptors, is active in man.
    Lancet (London, England), 1984, May-05, Volume: 1, Issue:8384

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Blood Platelets; Blood Vessels; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Random Allocation; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Vasoconstriction

1984

Other Studies

33 other study(ies) available for sulotroban and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid

ArticleYear
Effects of thromboxane agonists on cardiac adrenergic neurotransmission.
    European journal of pharmacology, 1992, Mar-17, Volume: 213, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Norepinephrine; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Sympathetic Nervous System; Synaptic Transmission; Thromboxane A2; Thromboxane B2

1992
Actions of the novel thromboxane A2 receptor antagonist sodium (E)-11-[2-(5,6-dimethyl-1-benzimidazolyl)-ethylidene]-6,11- dihydrodibenz[b,e]oxepine-1-carboxylate monohydrate on smooth muscle preparations.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzimidazoles; Benzoxepins; Blood Pressure; Cats; Dogs; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Phenylacetates; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Sulfonamides; Thromboxane A2

1991
Protective effects of the novel thromboxane A2 receptor antagonist sodium (E)-11-[2-(5,6-dimethyl-1-benzimidazolyl)-ethylidene]-6,11- dihydrodibenz[b,e]oxepine-2-carboxylate monohydrate against 9,11-dideoxy- 9 alpha, 11 alpha-epoxymethano-prostaglandin F2
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aspirin; Benzimidazoles; Benzoxepins; Blood Pressure; Death, Sudden; Dose-Response Relationship, Drug; Guinea Pigs; Male; Phenylacetates; Platelet Aggregation Inhibitors; Platelet Count; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Sulfonamides; Thromboxane A2; Thromboxanes; Ticlopidine

1991
Antiplatelet effects of the novel thromboxane A2 receptor antagonist sodium (E)-11-[2-(5,6-dimethyl-1-benzimidazolyl)-ethylidene]-6,11- dihydrodibenz[b,e] oxepine-2-carboxylate monohydrate.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Adult; Animals; Benzimidazoles; Benzoxepins; Cats; Dogs; Drug Interactions; Epinephrine; Guinea Pigs; Humans; In Vitro Techniques; Mice; Middle Aged; Phenylacetates; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Rabbits; Rats; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2

1991
Computer-aided molecular modeling of a thromboxane receptor antagonist S-145 and its related compounds.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Computer Simulation; Fatty Acids, Monounsaturated; Models, Molecular; Molecular Conformation; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Thromboxane A2

1990
Influence of SK&F 95587 and BN 50730 on bronchoconstrictor responses in the cat.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Azepines; Bronchoconstriction; Cats; Dose-Response Relationship, Drug; Female; Lung; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Receptors, Thromboxane; Respiration; Sulfonamides; Tetrazoles; Thienopyridines; Time Factors; Triazoles

1990
Effect of thromboxane A2 synthetase inhibition, singly and combined with thromboxane A2/prostaglandin endoperoxide receptor antagonism, on inositol phospholipid turnover and on 5-HT release by washed human platelets.
    European journal of pharmacology, 1990, Mar-13, Volume: 188, Issue:2-3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Collagen; Humans; In Vitro Techniques; Indomethacin; Inositol Phosphates; Methacrylates; Platelet Activating Factor; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Serotonin; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase

1990
Synergistic antiplatelet and antithrombotic effects of a prostacyclin analogue (iloprost) combined with a thromboxane antagonist (sulotroban) in guinea pigs and rats.
    Thrombosis research, 1988, Sep-15, Volume: 51, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cardiovascular Agents; Collagen; Drug Synergism; Epoprostenol; Fibrinolytic Agents; Guinea Pigs; Iloprost; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Rats; Sulfonamides; Thrombocytopenia; Thrombophlebitis; Thromboxanes

1988
The PGI2-analogue iloprost and the TXA2-receptor antagonist sulotroban synergistically inhibit TXA2-dependent platelet activation.
    Prostaglandins, 1988, Volume: 36, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Aspirin; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Drug Synergism; Epoprostenol; Fatty Acids, Unsaturated; Humans; Hydrazines; Iloprost; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Prostaglandins, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides

1988
The effect of substances influencing the arachidonic acid cascade on experimental cardiac arrhythmias.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:10-11

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Arrhythmia Agents; Arachidonic Acids; Arrhythmias, Cardiac; Epoprostenol; Guinea Pigs; Heart; Iloprost; Ouabain; Prostaglandin Endoperoxides, Synthetic; Reference Values; Sulfonamides

1988
Role of endoperoxides in arachidonic acid-induced vasoconstriction in the isolated perfused kidney of the rat.
    British journal of pharmacology, 1989, Volume: 96, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Arrhythmia Agents; Arachidonic Acids; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hydrazines; In Vitro Techniques; Kidney; Male; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins G; Prostaglandins H; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes; Vasoconstriction

1989
Role of eicosanoids and related mediators in gastric mucosal ulceration.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 16,16-Dimethylprostaglandin E2; Animals; Eicosanoids; Gastric Mucosa; Hydrogen Peroxide; Male; Prostaglandin Endoperoxides, Synthetic; Rats; Stomach; Stomach Ulcer; Sulfonamides

1989
The classification of prostaglandin DP-receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist.
    British journal of pharmacology, 1989, Volume: 96, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Platelets; Blood Vessels; Guinea Pigs; Humans; Hydantoins; In Vitro Techniques; Jugular Veins; Male; Muscle Contraction; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Rabbits; Receptors, Prostaglandin; Sulfonamides; Trachea

1989
Antiaggregatory effects of thromboxane receptor antagonists in vivo.
    Thrombosis research, 1985, Dec-01, Volume: 40, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Fatty Acids, Unsaturated; Fibrinolytic Agents; Hydrazines; Imidazoles; Kinetics; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Rabbits; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane-A Synthase; Thromboxanes

1985
Irreversible inhibition of the TXA2/PGH2 receptor of human platelets by a photoaffinity ligand.
    Biochemical pharmacology, 1988, Feb-01, Volume: 37, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Affinity Labels; Azides; Blood Platelets; Fibrinolytic Agents; Humans; Kinetics; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2

1988
Close-arterial administration of the thromboxane mimetic U-46619 induces damage to the rat gastric mucosa.
    Prostaglandins, 1988, Volume: 35, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 16,16-Dimethylprostaglandin E2; Animals; Arteries; Drug Synergism; Ethanol; Gastric Mucosa; Infusions, Intra-Arterial; Male; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Stomach; Stomach Ulcer; Sulfonamides

1988
Prostaglandin D2 interacts at thromboxane receptor-sites on guinea-pig platelets.
    British journal of pharmacology, 1986, Volume: 88, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Guinea Pigs; Male; Organophosphonates; Organophosphorus Compounds; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandins D; Prostanoic Acids; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides

1986
Effects of thromboxane A2 on lymphocyte proliferation.
    Cellular immunology, 1985, Volume: 90, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Antibodies, Monoclonal; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Imidazoles; Indomethacin; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes

1985
Effects of the prostaglandin H2/thromboxane A2 antagonist BM 13.177 on human platelets.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1985, Volume: 13

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Blood Platelets; Collagen; Humans; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Serotonin; Sulfonamides; Thrombin; Thromboxane A2; Thromboxanes

1985
Relevance of eicosanoids for biochemical regulation of cardiac rhythm disturbances.
    Biomedica biochimica acta, 1987, Volume: 46, Issue:8-9

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arrhythmias, Cardiac; Epoprostenol; Fatty Acids, Unsaturated; Guinea Pigs; Male; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Sulfonamides; Thromboxanes

1987
Protective effects of the thromboxane receptor antagonists BM 13.177 and BM 13.505 against U 46619-induced sudden death in rats.
    Pharmacology, 1988, Volume: 36, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Arrhythmia Agents; Death, Sudden; Dose-Response Relationship, Drug; Electrocardiography; Male; Phenylacetates; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Respiration; Sulfonamides; Thromboxanes

1988
Receptor-mediated effects of a PGH2 analogue (U 46619) on human platelets.
    The American journal of physiology, 1987, Volume: 253, Issue:5 Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Humans; Kinetics; Myosin-Light-Chain Kinase; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Serotonin; Sulfonamides

1987
Single dose pharmacokinetics and effects on platelet function of the thromboxane receptor blocker BM 13.177.
    European journal of clinical pharmacology, 1986, Volume: 29, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Blood Platelets; Fibrinolytic Agents; Humans; Kinetics; Male; Methylmercury Compounds; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Serotonin; Sulfonamides; Time Factors

1986
Inhibitory effects of the selective thromboxane receptor antagonist BM 13.177 on platelet aggregation, vasoconstriction and sudden death.
    Biomedica biochimica acta, 1984, Volume: 43, Issue:8-9

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Dinoprost; Humans; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins F; Rats; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Sulfonamides; Thromboxanes; Vasoconstriction

1984
The pharmacological profile of the thromboxane A2 antagonist BM 13.177. A new anti-platelet and anti-thrombotic drug.
    Thrombosis research, 1984, Aug-15, Volume: 35, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Epoprostenol; Female; Fibrinolytic Agents; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Rabbits; Sulfonamides; Thrombosis; Thromboxane A2; Thromboxane B2; Thromboxanes

1984
Investigation on a selective non-prostanoic thromboxane antagonist, BM 13.177, in human platelets.
    Thrombosis research, 1984, Feb-01, Volume: 33, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Epinephrine; Humans; Hydrogen Peroxide; Imidazoles; Indomethacin; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Serotonin; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxanes

1984
Receptor occupancy regulates Ca2+ entry and intracellular Ca2+ redistribution in activated human platelets.
    The Biochemical journal, 1994, Dec-15, Volume: 304 ( Pt 3)

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Cytosol; Epoprostenol; Humans; Intracellular Fluid; Nitroprusside; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Signal Transduction; Sulfonamides; Terpenes; Thapsigargin; Thromboxane A2

1994
Studies on the effects of agonists and antagonists on platelet shape change and platelet aggregation in whole blood.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1996, Volume: 7, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Azepines; Blood Platelets; Humans; In Vitro Techniques; Piperazines; Piperidines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Serotonin; Succinates; Sulfonamides; Thromboxane A2; Triazoles; Vasoconstrictor Agents

1996
Labeling of human platelet plasma membrane thromboxane A2/prostaglandin H2 receptors using SQB, a novel biotinylated receptor probe.
    Biochemical pharmacology, 1996, Sep-13, Volume: 52, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Biotin; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Fatty Acids, Unsaturated; Humans; Hydrazines; Microscopy, Fluorescence; Molecular Probes; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Radioligand Assay; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Spectrometry, Fluorescence; Sulfonamides; Thromboxane A2

1996
Involvement of platelet-derived 5-hydroxytryptamine in thromboxane A2-induced aggregation in cat platelets.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1998, Volume: 9, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Platelets; Cats; Collagen; Cyclooxygenase Inhibitors; Drug Interactions; Female; Indomethacin; Ketanserin; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin; Serotonin Antagonists; Sulfonamides; Thromboxane A2

1998
Activity of a novel dual thromboxane A(2)receptor antagonist and thromboxane synthase inhibitor (BM-573) on platelet function and isolated smooth muscles.
    Prostaglandins, leukotrienes, and essential fatty acids, 2001, Volume: 65, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antihypertensive Agents; Aorta; Arachidonic Acid; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Guinea Pigs; Humans; Hydrazines; Inhibitory Concentration 50; Models, Chemical; Muscle, Smooth; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Receptors, Thromboxane; Sulfonamides; Thromboxane-A Synthase; Torsemide; Trachea; Vasoconstrictor Agents

2001
Myocardial ischemia-mediated excitatory reflexes: a new function for thromboxane A2?
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anesthetics, Local; Animals; Cats; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Heart; Hemodynamics; Histamine H1 Antagonists; Indoles; Kidney; Male; Myocardial Ischemia; Pressoreceptors; Procaine; Pyrilamine; Receptors, Thromboxane; Reflex; Serotonin Antagonists; Sulfonamides; Sympathetic Nervous System; Thromboxane A2; Tropisetron; Vagotomy

2008
Kupffer cell activation by hydrogen peroxide: a new mechanism of portal pressure increase.
    Shock (Augusta, Ga.), 2010, Volume: 33, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Gadolinium; Hydrogen Peroxide; Kupffer Cells; Liver Cirrhosis; Male; Microfilament Proteins; Portal Pressure; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sulfonamides; Xanthine; Xanthine Oxidase

2010