sulfur has been researched along with ag-1549 in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 20 (95.24) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bartlett, JG | 1 |
| Gallant, JE | 1 |
| Auwerx, J; Balzarini, J; De Clercq, E; Esnouf, R | 1 |
| Tarby, CM | 1 |
| Amantea, MA; Bu, HZ; Pool, WF; Raber, SR; Shetty, BV; Wu, EY | 1 |
| Pauwels, R | 1 |
| Dahl, TA; Dezube, BJ; Fujiwara, T; Gewurz, BE; Jacobs, M; Proper, JA | 1 |
| el-Badawi, MA; el-Barbary, AA; Loksha, YM; Nielsen, C; Pedersen, EB | 1 |
| Bu, HZ; Kang, P; Pool, WF; Wu, EY; Zhao, P | 2 |
| Nelson, MR; Waters, L | 1 |
| Alexander, TN; Binford, S; Fujiwara, T; Graham, JP; Hammond, J; Patick, AK; Sato, A; Sugimoto, H; Sugita, K | 1 |
| Dupont, T; Jones, LH; Mowbray, CE; Newman, SD | 1 |
| Bu, HZ; Kang, P; Pool, WF; Shetty, BV; Wu, EY; Zhao, P | 1 |
| Amantea, MA; Nickens, DJ; Raber, SR; Reynolds, RR; Sarapa, N | 1 |
| Manallack, DT | 1 |
| Allan, G; Corbau, R; Hay, D; Jones, LH; Middleton, DS; Mowbray, CE; Newman, SD; Perros, M; Randall, A; Vuong, H; Webster, R; Westby, M; Williams, D | 1 |
| Allan, G; Barba, O; Burt, C; Corbau, R; Dupont, T; Irving, S; Jones, LH; Knöchel, T; Middleton, DS; Mowbray, CE; Perros, M; Phillips, C; Ringrose, H; Swain, NA; Webster, R; Westby, M | 1 |
| Bu, HZ; Pool, WF; Shetty, BV; Wu, EY | 1 |
| De Clercq, E; Li, X; Liu, X; Zhan, P | 1 |
4 review(s) available for sulfur and ag-1549
| Article | Year |
|---|---|
Recent advances in the development of next generation non-nucleoside reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Coumarins; HIV Reverse Transcriptase; Humans; Imidazoles; Molecular Structure; Nitriles; Patents as Topic; Pyranocoumarins; Pyridazines; Pyrimidines; Quinazolines; Reverse Transcriptase Inhibitors; Sulfur Compounds | 2004 |
New non-nucleoside reverse transcriptase inhibitors (NNRTIs) in development for the treatment of HIV infections.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Imidazoles; Models, Molecular; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfur Compounds | 2004 |
New drugs.
Topics: Anti-HIV Agents; Benzophenones; Cytidine Triphosphate; Darunavir; Deoxycytidine; Emtricitabine; HIV; HIV Fusion Inhibitors; HIV Reverse Transcriptase; Humans; Imidazoles; Nitriles; Protease Inhibitors; Pyridazines; Pyridines; Pyrimidines; Pyrones; Reverse Transcriptase Inhibitors; Sulfonamides; Sulfur Compounds; Zalcitabine | 2005 |
The HIV-1 non-nucleoside reverse transcriptase inhibitors (part V): capravirine and its analogues.
Topics: Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Imidazoles; Molecular Docking Simulation; Nucleosides; Protein Binding; Reverse Transcriptase Inhibitors; Sulfur Compounds | 2012 |
3 trial(s) available for sulfur and ag-1549
| Article | Year |
|---|---|
Metabolism and excretion of capravirine, a new non-nucleoside reverse transcriptase inhibitor, alone and in combination with ritonavir in healthy volunteers.
Topics: Administration, Oral; Anti-HIV Agents; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Feces; Humans; Imidazoles; Male; Reverse Transcriptase Inhibitors; Ritonavir; Spectrometry, Mass, Electrospray Ionization; Sulfur Compounds; Time Factors | 2004 |
Capravirine, a nonnucleoside reverse-transcriptase inhibitor in patients infected with HIV-1: a phase 1 study.
Topics: Administration, Oral; Anti-HIV Agents; CD4 Lymphocyte Count; Diarrhea; Female; HIV Infections; HIV-1; Humans; Imidazoles; Male; Nausea; Reverse Transcriptase Inhibitors; Sulfur Compounds; Viral Load | 2004 |
Ritonavir 100 mg does not cause QTc prolongation in healthy subjects: a possible role as CYP3A inhibitor in thorough QTc studies.
Topics: Adult; Aza Compounds; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Drug Therapy, Combination; Electrocardiography; Female; Fluoroquinolones; Heart Rate; HIV Protease Inhibitors; Humans; Imidazoles; Ketoconazole; Liver; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Quinolines; Reference Values; Reproducibility of Results; Research Design; Reverse Transcriptase Inhibitors; Ritonavir; Sulfur Compounds; Treatment Outcome | 2008 |
14 other study(ies) available for sulfur and ag-1549
| Article | Year |
|---|---|
Capravirine trials stopped.
Topics: Animals; Anti-HIV Agents; Clinical Trials as Topic; Dogs; HIV Infections; Humans; Imidazoles; Sulfur Compounds; Vasculitis | 2001 |
Report on new drugs.
Topics: Anti-HIV Agents; Antiviral Agents; Atazanavir Sulfate; Dioxolanes; Drugs, Investigational; Humans; Imidazoles; Lopinavir; Oligopeptides; Purine Nucleosides; Pyridines; Pyrimidinones; Pyrones; Sulfonamides; Sulfur Compounds | 2000 |
New antiretroviral agents.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Carbamates; Deoxycytidine; Dioxolanes; Drugs, Investigational; Emtricitabine; Furans; Guanosine; HIV Fusion Inhibitors; Humans; Imidazoles; Oligopeptides; Organophosphates; Organophosphonates; Organophosphorus Compounds; Prodrugs; Protease Inhibitors; Pyridines; Pyrones; Quinazolines; Reverse Transcriptase Inhibitors; Sulfonamides; Sulfur Compounds; Tenofovir | 2001 |
Susceptibility of feline immunodeficiency virus/human immunodeficiency virus type 1 reverse transcriptase chimeras to non-nucleoside RT inhibitors.
Topics: Amino Acid Sequence; Animals; Anti-HIV Agents; Catalysis; Cats; Deoxyguanine Nucleotides; Dideoxynucleotides; Foscarnet; HIV Reverse Transcriptase; HIV-1; Humans; Imidazoles; Immunodeficiency Virus, Feline; Kinetics; Molecular Sequence Data; Nevirapine; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Homology, Amino Acid; Species Specificity; Sulfur Compounds | 2004 |
Synthesis of 2-(aminocarbonylmethylthio)-1H-imidazoles as novel Capravirine analogues.
Topics: Anti-HIV Agents; Cell Line; HIV-1; Humans; Imidazoles; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfur Compounds; Virus Replication | 2005 |
A simple sequential incubation method for deconvoluting the complicated sequential metabolism of capravirine in humans.
Topics: Biotransformation; Carbon Radioisotopes; Humans; Imidazoles; In Vitro Techniques; Methods; Microsomes, Liver; Reverse Transcriptase Inhibitors; Sulfur Compounds | 2005 |
In vitro selection of mutations in human immunodeficiency virus type 1 reverse transcriptase that confer resistance to capravirine, a novel nonnucleoside reverse transcriptase inhibitor.
Topics: Anti-HIV Agents; Drug Resistance, Viral; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Imidazoles; Mutagenesis, Site-Directed; Mutation; Reverse Transcriptase Inhibitors; Sequence Analysis, DNA; Sulfur Compounds | 2006 |
A concise and selective synthesis of novel 5-aryloxyimidazole NNRTIs.
Topics: Anti-HIV Agents; Imidazoles; Molecular Structure; Reverse Transcriptase Inhibitors; Sulfur Compounds | 2006 |
Identification of enzymes responsible for primary and sequential oxygenation reactions of capravirine in human liver microsomes.
Topics: Anti-HIV Agents; Biotransformation; Cytochrome P-450 Enzyme System; Humans; Imidazoles; In Vitro Techniques; Microsomes, Liver; Molecular Structure; Oxidation-Reduction; Sulfur Compounds | 2006 |
Evaluation of capravirine as a CYP3A probe substrate: in vitro and in vivo metabolism of capravirine in rats and dogs.
Topics: Animals; Anti-HIV Agents; Antibodies, Blocking; Biotransformation; Chromatography, Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dogs; Imidazoles; In Vitro Techniques; Male; Mass Spectrometry; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Ritonavir; Species Specificity; Substrate Specificity; Sulfur Compounds | 2007 |
The use of local surface properties for molecular superimposition.
Topics: Amino Acid Chloromethyl Ketones; Anti-HIV Agents; Anticoagulants; Antimetabolites, Antineoplastic; Crystallography, X-Ray; Dipeptides; Folic Acid; HIV Protease Inhibitors; Humans; Imidazoles; Ligands; Methotrexate; Models, Molecular; Molecular Structure; Piperidines; Protein Binding; Proteins; Quinoxalines; Reverse Transcriptase Inhibitors; Software; Static Electricity; Structure-Activity Relationship; Sulfur Compounds; Surface Properties; Tetrahydrofolate Dehydrogenase | 2008 |
Optimization of 5-aryloxyimidazole non-nucleoside reverse transcriptase inhibitors.
Topics: Acquired Immunodeficiency Syndrome; Allosteric Site; Antiviral Agents; Cell Line; Chemistry, Pharmaceutical; Drug Design; Drug Resistance, Viral; HIV Reverse Transcriptase; Humans; Imidazoles; Inhibitory Concentration 50; Models, Chemical; Mutation; Reverse Transcriptase Inhibitors; Sulfur Compounds | 2008 |
Novel indazole non-nucleoside reverse transcriptase inhibitors using molecular hybridization based on crystallographic overlays.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Crystallography, X-Ray; Cyclopropanes; Drug Design; Drug Resistance, Viral; Drug Stability; HIV; HIV Reverse Transcriptase; Humans; Imidazoles; Indazoles; Molecular Structure; Mutation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfur Compounds | 2009 |
A unique example of drug metabolism: tetra- and penta-oxygenation reactions of capravirine in rats, dogs and humans.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Chromatography, High Pressure Liquid; Dogs; Humans; Imidazoles; Isomerism; Mass Spectrometry; Oxygen; Rats; Rats, Sprague-Dawley; Species Specificity; Sulfur Compounds | 2007 |