Page last updated: 2024-08-16

sulforaphane and phenethyl isothiocyanate

sulforaphane has been researched along with phenethyl isothiocyanate in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.38)18.2507
2000's13 (30.95)29.6817
2010's24 (57.14)24.3611
2020's4 (9.52)2.80

Authors

AuthorsStudies
Lai, B; Liang, H; Yuan, Q1
Amin, S; Desai, D; Emmert, SW; Richie, JP1
Chung, FL; Di Pasqua, AJ; Fine, RL; Govind, S; Hong, C; Mao, Y; McCracken, E; Mi, L; Tomita, Y; Wang, X; Woodrick, JC; Wu, JY1
Dale, EJ; Gamble, AB; Gommans, AL; Hampton, MB; Nakatani, Y; Rutledge, MT; Smith, RA; Spencer, ES; Tyndall, JD; Vo, CT; Wilbanks, SM1
Barcelo, S; Chipman, JK; Gardiner, JM; Gescher, A1
Chung, FL; Conaway, CC; Rao, CV; Reddy, BS1
Bammler, TK; Buhler, DR; Eaton, DL; Farin, FM; Gross-Steinmeyer, K; Liu, F; Quigley, SD; Safe, SH; Stapleton, PL; Strom, SC; Tracy, JH1
Chen, C; Gélinas, C; Kong, AN; Shen, G; Xu, C1
Chung, FL; Conaway, CC; Hecht, SS; McIntee, EJ; Pittman, B; Schwartz, JE; Tian, D; Wang, CX; Yang, YM1
Gopalkrishnan, A; Keum, YS; Kim, JH; Kong, AN; Nair, S; Shen, G; Xu, C; Yuan, X1
Barillari, J; Bartsch, H; Gerhäuser, C; Iori, R; Lichtenberg, M; Pappa, G1
Li, G; Song, L; Tang, L; Zhang, Y1
Chung, FL; Conrads, TP; Goldman, R; Govind, S; Hood, BL; Mi, L; Saha, DT; Veenstra, TD; Wang, X1
Cheung, KL; Khor, TO; Kong, AN1
Chung, FL; Mi, L1
Brazeau, DA; Morris, ME; Telang, U1
Chung, FL; Gan, N; Mi, L1
Cheung, KL; Kong, AN1
Kumar, A; Sabbioni, G1
Bammler, TK; Eaton, DL; Gross-Steinmeyer, K; Stapleton, PL; Strom, SC; Tracy, JH1
Han, W; Shi, M; Spivack, SD; Tan, XL; Tang, H1
Coldham, N; Hanlon, N; Ioannides, C; Konsue, N; Sauer, MJ1
Anderson, KC; Blotta, S; Cervi, D; Cholujova, D; Daley, JF; Delmore, J; Hideshima, T; Jakubikova, J; Kim, K; Klippel, S; Leiba, M; McMillin, DW; Mitsiades, CS; Nahar, S; Negri, J; Ooi, M; Richardson, PG; Sedlak, J1
Ho, JN; Jeon, H; Jun, W; Kang, ER; Lee, J; Watson, RR; Yoon, HG1
Graeser, AC; Huebbe, P; Rimbach, G; Schrader, C; Wagner, AE1
Choue, R; Ho, JN; Jun, W; Kim, S; Lee, J; Park, CS; Yoon, HG1
Coyle, EM; Ghosh, A; Hahm, ER; Lee, J; Sarkar, SN; Singh, SV; Zhu, J1
Gerhauser, C1
Jeffery, EH; Juvik, JA; Ku, KM1
Ernst, IM; Fischer, TW; Kleszczyński, K; Kruse, N; Rimbach, G; Wagner, AE; Zillikens, D1
Amjad, AI; Chinni, SR; Parikh, R; Sakao, K; Singh, SV; Vyas, AR1
De Nicola, GR; Esatbeyoglu, T; Iori, R; Piegholdt, S; Rimbach, G; Sturm, C; Wagner, AE; Wolf, IM1
Bae, YS; Chang, HW; Chang, YC; Cho, HJ; Chung, IK; Jeong, YJ; Jin, F; Kim, CH; Kim, M; Lee, CS; Park, KK; Park, YY; Shin, JM1
Gao, L; Kong, AN; Li, W; Ramirez, CN; Su, S; Wang, C; Wu, R; Yin, R; Zhang, C1
Abdull Razis, AF; Ioannides, C; Konsue, N1
Fahey, JW; Kensler, TW; Palliyaguru, DL; Yuan, JM1
Abd Karim, NA; Abdull Razis, AF; Enas, ME; Jaafaru, MS; Mazzon, E; Rollin, P1
Bogucka, K; Herman-Antosiewicz, A; Maciąg-Dorszyńska, M; Nowicki, D; Szalewska-Pałasz, A1
Fasano, A; Larocca, M; Latronico, T; Liuzzi, GM; Milella, S; Rossano, R1
Herman-Antosiewicz, A; Karczewska, M; Krause, K; Narajczyk, M; Nowicki, D; Pyrczak-Felczykowska, A; Szalewska-Pałasz, A1
Karczewska, M; Krause, K; Nowicki, D; Szalewska-Pałasz, A1
Hayashi, I; Kainoh, M; Konno, M; Majima, Y; Moriyama, M; Serizawa, K; Suzuki, T; Yuzawa, N1

Reviews

6 review(s) available for sulforaphane and phenethyl isothiocyanate

ArticleYear
Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention.
    The AAPS journal, 2010, Volume: 12, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Cycle; Cytochrome P-450 Enzyme Inhibitors; Diet; Enzyme Induction; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; MAP Kinase Signaling System; Neoplasms; NF-E2-Related Factor 2; NF-kappa B; Sulfoxides; Thiocyanates

2010
Epigenetic impact of dietary isothiocyanates in cancer chemoprevention.
    Current opinion in clinical nutrition and metabolic care, 2013, Volume: 16, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Brassica; Catechin; Chemoprevention; Diet; DNA Methylation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; MicroRNAs; Neoplasms; NF-E2-Related Factor 2; Signal Transduction; Sulfoxides

2013
Isothiocyanates and Xenobiotic Detoxification.
    Molecular nutrition & food research, 2018, Volume: 62, Issue:18

    Topics: Animals; Carcinogens; Cell Line, Tumor; Disease Models, Animal; DNA Damage; Epoxide Hydrolases; Glucosinolates; Glucuronosyltransferase; Glutathione Transferase; Hepatocytes; Humans; Inactivation, Metabolic; Isothiocyanates; Sulfides; Sulfoxides; Thiocyanates; Xenobiotics

2018
Isothiocyanates: Translating the Power of Plants to People.
    Molecular nutrition & food research, 2018, Volume: 62, Issue:18

    Topics: Brassica; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Humans; Isothiocyanates; Neoplasms; Skin Diseases; Sulfoxides; Treatment Outcome; Vegetables

2018
Protective Effect of Glucosinolates Hydrolytic Products in Neurodegenerative Diseases (NDDs).
    Nutrients, 2018, May-08, Volume: 10, Issue:5

    Topics: Brassica; Glucosinolates; Humans; Isothiocyanates; Neurodegenerative Diseases; Neuroprotective Agents; Sulfides; Sulfoxides; Thiocyanates; Vegetables

2018
Anti-pruritic effect of isothiocyanates: Potential involvement of toll-like receptor 3 signaling.
    Pharmacology research & perspectives, 2022, Volume: 10, Issue:6

    Topics: Animals; Antipruritics; Chloroquine; Humans; Mice; Mice, Knockout; Pruritus; Skin; Toll-Like Receptor 3

2022

Other Studies

36 other study(ies) available for sulforaphane and phenethyl isothiocyanate

ArticleYear
Sulforaphane induces cell-cycle arrest and apoptosis in cultured human lung adenocarcinoma LTEP-A2 cells and retards growth of LTEP-A2 xenografts in vivo.
    Journal of natural products, 2008, Volume: 71, Issue:11

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Anticarcinogenic Agents; Apoptosis; Brassica; Cell Cycle; Dose-Response Relationship, Drug; Humans; Isothiocyanates; Lung Neoplasms; Mice; Sulfoxides; Thiocyanates; Transplantation, Heterologous

2008
Enhanced Nrf2-dependent induction of glutathione in mouse embryonic fibroblasts by isoselenocyanate analog of sulforaphane.
    Bioorganic & medicinal chemistry letters, 2010, Apr-15, Volume: 20, Issue:8

    Topics: Animals; Cell Line, Tumor; Cyanates; Embryo, Mammalian; Fibroblasts; Glutathione; Humans; Isothiocyanates; Mice; NF-E2-Related Factor 2; Sulfoxides; Thiocyanates

2010
Selective depletion of mutant p53 by cancer chemopreventive isothiocyanates and their structure-activity relationships.
    Journal of medicinal chemistry, 2011, Feb-10, Volume: 54, Issue:3

    Topics: Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cysteine; Drug Screening Assays, Antitumor; Humans; Isothiocyanates; Mutation; Protein Conformation; Structure-Activity Relationship; Tumor Suppressor Protein p53

2011
Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor.
    European journal of medicinal chemistry, 2015, Mar-26, Volume: 93

    Topics: Drug Design; Enzyme Inhibitors; Humans; Intramolecular Oxidoreductases; Isothiocyanates; Jurkat Cells; Macrophage Migration-Inhibitory Factors; Molecular Docking Simulation; Protein Binding; Protein Conformation

2015
CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane.
    Carcinogenesis, 1996, Volume: 17, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Azides; Biotransformation; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; DNA Repair; Isothiocyanates; Male; Mice; Mice, Inbred BALB C; Mixed Function Oxygenases; Mutagenicity Tests; Nitroso Compounds; Oxidoreductases, N-Demethylating; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Sodium Azide; Sulfoxides; Thiocyanates

1996
Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate.
    Carcinogenesis, 2000, Volume: 21, Issue:12

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Brassica; Carcinogens; Colon; Colonic Neoplasms; Genotype; Glutathione Transferase; Humans; Intestinal Mucosa; Isothiocyanates; Male; Rats; Rats, Inbred F344; Sulfoxides; Thiocyanates; Vegetables

2000
Phytochemical-induced changes in gene expression of carcinogen-metabolizing enzymes in cultured human primary hepatocytes.
    Xenobiotica; the fate of foreign compounds in biological systems, 2004, Volume: 34, Issue:7

    Topics: Anticarcinogenic Agents; Carcinogens; Carrier Proteins; Curcumin; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Enzymes; Flavanones; Gene Expression Regulation; Glutathione Transferase; Hepatocytes; Humans; Inactivation, Metabolic; Indoles; Isothiocyanates; NAD(P)H Dehydrogenase (Quinone); Plants; Sulfoxides; Thiocyanates

2004
Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells.
    Oncogene, 2005, Jun-30, Volume: 24, Issue:28

    Topics: Anticarcinogenic Agents; bcl-X Protein; Cell Line, Tumor; Cell Survival; Cyclin D1; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; I-kappa B Kinase; I-kappa B Proteins; Isothiocyanates; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Sulfoxides; Thiocyanates; Transcription, Genetic; Vascular Endothelial Growth Factor A

2005
Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.
    Cancer research, 2005, Sep-15, Volume: 65, Issue:18

    Topics: Acetylcysteine; Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Body Weight; Carcinogens; Caspase 3; Caspases; Cell Growth Processes; Disease Progression; Female; In Situ Nick-End Labeling; Isothiocyanates; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Smoking; Sulfoxides; Thiocyanates

2005
ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells.
    Carcinogenesis, 2006, Volume: 27, Issue:3

    Topics: Anticarcinogenic Agents; Apoptosis; Extracellular Signal-Regulated MAP Kinases; Food Preservatives; Humans; Isothiocyanates; JNK Mitogen-Activated Protein Kinases; Male; Prostatic Neoplasms; Signal Transduction; Sulfoxides; Thiocyanates; Transcription Factor AP-1; Transcription, Genetic; Transfection; Tumor Cells, Cultured

2006
Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae.
    Mutation research, 2006, Jul-25, Volume: 599, Issue:1-2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brassicaceae; Caspase 7; Caspase 9; Caspases; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Gene Expression Profiling; Genes, p53; Humans; Indoles; Isothiocyanates; Phytotherapy; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Sulfoxides; Thiocyanates

2006
The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells.
    Anti-cancer drugs, 2006, Volume: 17, Issue:3

    Topics: Acetylcysteine; Apoptosis; Cell Cycle; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Isothiocyanates; Sulfoxides; Thiocyanates; Urinary Bladder Neoplasms

2006
The role of protein binding in induction of apoptosis by phenethyl isothiocyanate and sulforaphane in human non-small lung cancer cells.
    Cancer research, 2007, Jul-01, Volume: 67, Issue:13

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cattle; Cell Line, Tumor; DNA Damage; Humans; Isothiocyanates; Lung Neoplasms; Oxidative Stress; Protein Binding; Reactive Oxygen Species; Serum Albumin, Bovine; Sulfoxides; Thiocyanates

2007
Synergistic effect of combination of phenethyl isothiocyanate and sulforaphane or curcumin and sulforaphane in the inhibition of inflammation.
    Pharmaceutical research, 2009, Volume: 26, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Biomarkers; Cell Line; Curcumin; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Interleukin-1; Isothiocyanates; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitric Oxide Synthase Type II; Reverse Transcriptase Polymerase Chain Reaction; Sulfoxides; Thiocyanates; Tumor Necrosis Factor-alpha

2009
Binding to protein by isothiocyanates: a potential mechanism for apoptosis induction in human non small lung cancer cells.
    Nutrition and cancer, 2008, Volume: 60 Suppl 1

    Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cysteine; DNA Damage; Humans; Isothiocyanates; Lung Neoplasms; Oxidative Stress; Protein Binding; Protein Carbonylation; Sulfoxides; Thiocyanates; Tubulin

2008
Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells.
    Experimental biology and medicine (Maywood, N.J.), 2009, Volume: 234, Issue:3

    Topics: Breast Neoplasms; Cell Line; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Mammary Glands, Human; Oligonucleotide Array Sequence Analysis; Sulfoxides; Thiocyanates

2009
Aggresome-like structure induced by isothiocyanates is novel proteasome-dependent degradation machinery.
    Biochemical and biophysical research communications, 2009, Oct-16, Volume: 388, Issue:2

    Topics: Anticarcinogenic Agents; Biomarkers; Cytoplasm; HeLa Cells; Humans; Isothiocyanates; Proteasome Endopeptidase Complex; Protein Folding; Sulfoxides; Thiocyanates; Tubulin

2009
New biomarkers for monitoring the levels of isothiocyanates in humans.
    Chemical research in toxicology, 2010, Apr-19, Volume: 23, Issue:4

    Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Hemoglobins; Humans; Isothiocyanates; Kinetics; Lysine; Mice; Rats; Serum Albumin; Spectrometry, Mass, Electrospray Ionization; Sulfoxides; Thiocyanates

2010
Sulforaphane- and phenethyl isothiocyanate-induced inhibition of aflatoxin B1-mediated genotoxicity in human hepatocytes: role of GSTM1 genotype and CYP3A4 gene expression.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 116, Issue:2

    Topics: Aflatoxin B1; Cells, Cultured; Cytochrome P-450 CYP3A; DNA Adducts; DNA Repair; Genotype; Glutathione Transferase; Hepatocytes; Humans; Isothiocyanates; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfoxides; Thiocyanates

2010
Candidate dietary phytochemicals modulate expression of phase II enzymes GSTP1 and NQO1 in human lung cells.
    The Journal of nutrition, 2010, Volume: 140, Issue:8

    Topics: Anticarcinogenic Agents; Brassica; Bronchi; Camellia sinensis; Catechin; Cell Division; Cell Line; Cell Line, Tumor; Epithelial Cells; Gene Expression; Glutathione S-Transferase pi; Humans; Isothiocyanates; Lung; Lung Neoplasms; NAD(P)H Dehydrogenase (Quinone); Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfoxides; Thiocyanates

2010
Exposure to isothiocyanates suppresses urinary mutagenicity in rats treated with heterocyclic amine IQ: lack of association with CYP1 activity.
    Nutrition and cancer, 2011, Volume: 63, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cytochrome P-450 CYP1A2; Cytochromes; Glutathione Transferase; Isothiocyanates; Liver; Male; Mutagenicity Tests; Mutagens; Quinolines; Rats; Rats, Wistar; Sulfides; Sulfoxides; Thiocyanates

2011
Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma.
    Haematologica, 2011, Volume: 96, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line; Cell Proliferation; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Isothiocyanates; Mice; Mice, SCID; Multiple Myeloma; Signal Transduction; Stromal Cells; Sulfoxides; Thiocyanates; Tumor Burden; Xenograft Model Antitumor Assays

2011
Inhibition of premature death by isothiocyanates through immune restoration in LP-BM5 leukemia retrovirus-infected C57BL/6 mice.
    Bioscience, biotechnology, and biochemistry, 2011, Volume: 75, Issue:7

    Topics: Animals; Cytokines; Disease Progression; Female; Isothiocyanates; Lipid Peroxidation; Longevity; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Oxidative Stress; Sulfoxides; Th1 Cells; Th2 Cells; Thiocyanates; Vitamin E

2011
Allyl isothiocyanate as a potential inducer of paraoxonase-1--studies in cultured hepatocytes and in mice.
    IUBMB life, 2012, Volume: 64, Issue:2

    Topics: Animals; Aryldialkylphosphatase; Cell Line, Tumor; Cell Survival; Enzyme Induction; Female; Hepatocytes; Humans; Isothiocyanates; Liver; Mice; Mice, Inbred C57BL; Sulfoxides; Thiocyanates; Transcription, Genetic; Transcriptional Activation

2012
Isothiocyanates ameliorate the symptom of heart dysfunction and mortality in a murine AIDS model by inhibiting apoptosis in the left ventricle.
    Journal of medicinal food, 2012, Volume: 15, Issue:9

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cardiotonic Agents; Dietary Supplements; Female; Gene Expression Regulation; Heart Ventricles; Isothiocyanates; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; NF-kappa B; Nitric Oxide Synthase Type II; Random Allocation; RNA, Messenger; Sulfoxides; Survival Analysis; Thiocyanates; Ventricular Dysfunction, Left

2012
Differential effects of phenethyl isothiocyanate and D,L-sulforaphane on TLR3 signaling.
    Journal of immunology (Baltimore, Md. : 1950), 2013, Apr-15, Volume: 190, Issue:8

    Topics: Cell Line; Cell Line, Tumor; HEK293 Cells; Humans; Interferon Regulatory Factor-3; Isothiocyanates; NF-kappa B; Signal Transduction; Sulfoxides; Thiocyanates; Toll-Like Receptor 3

2013
Influence of seasonal variation and methyl jasmonate mediated induction of glucosinolate biosynthesis on quinone reductase activity in broccoli florets.
    Journal of agricultural and food chemistry, 2013, Oct-09, Volume: 61, Issue:40

    Topics: Acetates; Brassica; Cyclopentanes; Glucosinolates; Hydrolysis; Imidoesters; Indoles; Isothiocyanates; NAD(P)H Dehydrogenase (Quinone); Oximes; Oxylipins; Plant Proteins; Seasons; Sulfoxides

2013
Sulforaphane and phenylethyl isothiocyanate protect human skin against UVR-induced oxidative stress and apoptosis: role of Nrf2-dependent gene expression and antioxidant enzymes.
    Pharmacological research, 2013, Volume: 78

    Topics: Anticarcinogenic Agents; Apoptosis; Caspase 3; Catalase; Cell Line; Gene Expression Regulation; Humans; Isothiocyanates; NF-E2-Related Factor 2; Oxidative Stress; Skin; Sulfoxides; Ultraviolet Rays

2013
CXCR4 is a novel target of cancer chemopreventative isothiocyanates in prostate cancer cells.
    Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:5

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Cell Line, Tumor; Chemoprevention; Humans; Isothiocyanates; Male; Mice; Mice, Transgenic; Molecular Targeted Therapy; Prostatic Neoplasms; Receptors, CXCR4; RNA, Small Interfering; Sulfoxides; Xenograft Model Antitumor Assays

2015
Myrosinase-treated glucoerucin is a potent inducer of the Nrf2 target gene heme oxygenase 1--studies in cultured HT-29 cells and mice.
    The Journal of nutritional biochemistry, 2015, Volume: 26, Issue:6

    Topics: Animals; Brain; Diet, High-Fat; Female; Glucose; Glucosinolates; Glycoside Hydrolases; Heme Oxygenase-1; HT29 Cells; Humans; Imidoesters; Intestinal Mucosa; Intestines; Isothiocyanates; Liver; Membrane Proteins; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 3; Mustard Plant; NF-E2-Related Factor 2; Oximes; p38 Mitogen-Activated Protein Kinases; Plant Extracts; RNA, Messenger; Signal Transduction; Sulfoxides; Up-Regulation

2015
Isothiocyanates inhibit the invasion and migration of C6 glioma cells by blocking FAK/JNK-mediated MMP-9 expression.
    Oncology reports, 2015, Volume: 34, Issue:6

    Topics: Cell Line, Tumor; Cell Movement; Extracellular Matrix; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Glioma; Humans; Isothiocyanates; MAP Kinase Kinase 4; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Sulfoxides; Transcription Factor AP-1

2015
In Vitro-In Vivo Dose Response of Ursolic Acid, Sulforaphane, PEITC, and Curcumin in Cancer Prevention.
    The AAPS journal, 2017, 12-20, Volume: 20, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Cell Line, Tumor; Chemoprevention; Curcumin; Dose-Response Relationship, Drug; Humans; Isothiocyanates; NF-E2-Related Factor 2; Sulfoxides; Triterpenes; Ursolic Acid

2017
Various modes of action of dietary phytochemicals, sulforaphane and phenethyl isothiocyanate, on pathogenic bacteria.
    Scientific reports, 2019, 09-23, Volume: 9, Issue:1

    Topics: Bacillus subtilis; Escherichia coli; Isothiocyanates; Klebsiella pneumoniae; Phytochemicals; Staphylococcus aureus; Sulfoxides

2019
Neuroprotective potential of isothiocyanates in an in vitro model of neuroinflammation.
    Inflammopharmacology, 2021, Volume: 29, Issue:2

    Topics: Animals; Astrocytes; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Isothiocyanates; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neuroprotective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfoxides

2021
Dietary Isothiocyanates, Sulforaphane and 2-Phenethyl Isothiocyanate, Effectively Impair
    International journal of molecular sciences, 2021, Sep-22, Volume: 22, Issue:19

    Topics: Animals; Anti-Bacterial Agents; Biofilms; Cell Line; Chlorocebus aethiops; Cholera; Disease Models, Animal; DNA; Guanosine Tetraphosphate; HeLa Cells; Humans; Isothiocyanates; Microbial Sensitivity Tests; Moths; Nucleic Acid Synthesis Inhibitors; RNA; Sulfoxides; Vero Cells; Vibrio cholerae; Virulence; Virulence Factors

2021
Evaluation of the Anti-Shigellosis Activity of Dietary Isothiocyanates in
    Nutrients, 2021, Nov-07, Volume: 13, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Chlorocebus aethiops; Diet; HeLa Cells; Hemocytes; Humans; Isothiocyanates; Larva; Microbial Sensitivity Tests; Moths; Phagocytosis; Shiga Toxin; Shigella dysenteriae; Sulfoxides; Vero Cells

2021