sulforaphane has been researched along with glucoraphanin in 78 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.28) | 18.2507 |
| 2000's | 5 (6.41) | 29.6817 |
| 2010's | 57 (73.08) | 24.3611 |
| 2020's | 15 (19.23) | 2.80 |
| Authors | Studies |
|---|---|
| Bernardi, R; Gueyrard, D; Iori, R; Palmieri, S; Rollin, P | 1 |
| Botero-Omary, M; Chung, FL; Conaway, CC; Getahun, SM; Liebes, LL; Pusateri, DJ; Topham, DK | 1 |
| Jeffery, EH; Matusheski, NV | 1 |
| Jeffery, EH; Juvik, JA; Matusheski, NV | 1 |
| Abdel-Rahman, SZ; Affatato, A; Barillari, J; Broccoli, M; Bronzetti, G; Canistro, D; Iori, R; Legator, MS; Paolini, M; Pedulli, GF; Perocco, P; Pozzetti, L; Sapone, A; Sblendorio, V; Valgimigli, L | 1 |
| Bueno-Solano, C; Camacho-Gil, F; Campas-Baypoli, ON; Lóez-Cervantes, J; Martínez-Ibarra, DM; Rodríguez-Núñez, JR; Sánchez-Machado, DI; Villa-Lerma, AG | 1 |
| Bueno-Solano, C; Campas-Baypoli, ON; López-Cervantes, J; Ramírez-Wong, B; Sánchez-Machado, DI | 1 |
| Jeffery, EH; Lai, RH; Soendergaard, M; Zhu, N | 1 |
| Abdull Razis, AF; Bagatta, M; De Nicola, GR; Ioannides, C; Iori, R | 2 |
| Brauer, MN; Brigelius-Flohé, R; Glatt, H; Haack, M; Iori, R; Kipp, A; Lippmann, D; Löwinger, M; Monien, BH; Pagnotta, E; Wessjohann, LA | 1 |
| Cramer, JM; Jeffery, EH | 1 |
| Botting, NP; Chen, JG; Chen, TY; Chen, YS; Egner, PA; Fahey, JW; Friesen, MD; Groopman, JD; Jacobson, LP; Kensler, TW; Lu, JH; Muñoz, A; Ng, D; Qian, GS; Sun, Y; Talalay, P; Wang, JB; Wu, Y; Zhang, Q; Zhang, YH; Zhu, J; Zhu, YR | 1 |
| Jeffery, E; Lai, RH; Miller, MJ | 1 |
| Cramer, JM; Jeffery, EH; Teran-Garcia, M | 1 |
| Bella, D; Clarke, JD; Ho, E; Riedl, K; Schwartz, SJ; Stevens, JF | 1 |
| Liang, H; Yuan, Q | 1 |
| Carmella, SG; Chen, JG; Chen, M; Chen, TY; Egner, PA; Fahey, JW; Groopman, JD; Hecht, SS; Jacobson, LP; Kensler, TW; Muñoz, A; Ng, D; Qian, GS; Talalay, P; Yuan, JM | 1 |
| Chen, Z; Gu, Y; Gu, Z; Guo, Q; Han, Y; Zhang, L | 1 |
| Liang, H; Liu, M; Yuan, Q | 1 |
| Barrett, DA; Hollands, W; Kroon, PA; Mithen, RF; Narbad, A; Needs, PW; Ortori, CA; Rossiter, JT; Saha, S; Teucher, B | 1 |
| Bellur, P; Boddupalli, S; Devaraj, S; James, D; Lakkanna, S; Vicini, J | 1 |
| Ghawi, SK; Methven, L; Niranjan, K | 1 |
| Blaut, M; Brigelius-Flohé, R; Budnowski, J; Haack, M; Hanschen, FS; Hanske, L; Kroh, LW; Lehmann, C; Rohn, S | 1 |
| Dosz, EB; Jeffery, EH | 1 |
| Angeloni, C; Hrelia, P; Hrelia, S; Malaguti, M; Morroni, F; Tarozzi, A | 1 |
| Abdull Razis, AF; Noor, NM | 1 |
| Jeffery, EH; Juvik, JA; Ku, KM | 1 |
| Dominguez-Perles, R; Ferreres, F; García-Viguera, C; Gil-Izquierdo, Á; Medina, S; Moreno, DÁ | 1 |
| Barrientos, H; Mahn, A; Pérez, C; Román, J | 1 |
| Bennett, M; Luang-In, V; Mithen, R; Narbad, A; Nueno-Palop, C; Rossiter, JT | 1 |
| Gu, Z; Guo, L; Guo, Q; Wang, Z; Yang, R | 1 |
| Dekker, M; Oliviero, T; Verkerk, R; Vermeulen, M | 1 |
| Barknowitz, G; Brigelius-Flohé, R; Florian, S; Glatt, H; Haack, M; Kipp, AP; Lehmann, C; Lippmann, D; Mewis, I; Schreiner, M; Wiesner, M | 1 |
| De Nicola, GR; Iori, R; Mazzon, E; Rollin, P | 1 |
| Carmella, SG; Chen, JG; Chen, TY; Egner, PA; Fahey, JW; Groopman, JD; Hecht, SS; Jacobson, LP; Johnson, JL; Kensler, KH; Kensler, TW; Muñoz, A; Ng, DK; Qian, GS; Talalay, P; Wang, JB; Zarth, AT; Zhu, J | 1 |
| Bricker, GV; Oberyszyn, TM; Ralston, RA; Riedl, KM; Schwartz, SJ; Tober, KL | 1 |
| Domínguez-Perles, R; Ferreres, F; García-Viguera, C; Gil, JI; Gil-Izquierdo, Á; Medina, S; Moreno, DA | 1 |
| Conzatti, A; Fróes, FC; Schweigert Perry, ID; Souza, CG | 1 |
| De Nicola, GR; Esatbeyoglu, T; Iori, R; Piegholdt, S; Rimbach, G; Sturm, C; Wagner, AE; Wolf, IM | 1 |
| Glade, MJ; Meguid, MM | 1 |
| Fahey, JW; Holtzclaw, WD; Stephenson, KK; Talalay, P; Wade, KL; Wehage, SL | 1 |
| Bunch, R; Felker, P; Leung, AM | 1 |
| Kensler, TW; Palliyaguru, DL; Yang, L | 1 |
| Dong, C; Han, M; Hashimoto, K; Ma, M; Ren, Q; Suganuma, H; Ushida, Y; Wu, J; Yang, C; Yao, W; Zhang, JC | 1 |
| Fahey, JW; Fuchs, E; Holtzclaw, WD; Liu, H; Stephenson, KK; Talalay, P; Wade, KL; Wehage, SL | 1 |
| Di Giacomo, M; Ferramosca, A; Zara, V | 1 |
| Aguayo, E; Artés, F; Artés-Hernández, F; Castillejo, N; Gómez, PA; Lozano-Guerrero, AJ; Martínez-Hernández, GB; Pedreño-Molina, JL | 1 |
| Dainty, JR; Melchini, A; Mithen, RF; Needs, PW; Saha, S; Sivapalan, T; Tapp, H; Traka, MH | 1 |
| Capuano, E; Dekker, M; Lamers, S; Oliviero, T; Verkerk, R | 1 |
| Castillo, A; Cottet, L; Mahn, A; Román, J | 1 |
| Ghawi, SK; Kuhnle, G; Methven, L; Niranjan, K; Okunade, O | 1 |
| Artés Calero, F; Artés-Hernández, F; Carrión-Monteagudo, MDM; López-Nicolás, JM; Martínez-Hernández, GB; Venzke-Klug, T | 1 |
| Baima, S; Bello, C; Maldini, M; Natella, F; Scaccini, C | 1 |
| Calderone, V; Citi, V; De Nicola, GR; Di Cesare Mannelli, L; Ghelardini, C; Iori, R; Lucarini, E; Martelli, A; Micheli, L; Testai, L; Trallori, E | 1 |
| Anzenbacher, P; Anzenbacherova, E; Vanduchova, A | 1 |
| Charron, CS; Jeffery, EH; Novotny, JA; Ross, SA; Seifried, HE; Vinyard, BT | 1 |
| Hung, YC; Jiang, Z; Li, L; Liu, H; Nirasawa, S; Song, S | 1 |
| Fang, Z; Li, L; Li, Z; Liu, Y; Lv, H; Yang, L; Zhang, Y; Zhuang, M | 1 |
| Al Kadhi, O; Ball, RY; Bernuzzi, F; Coode-Bate, J; Cooper, CS; Dainty, JR; Defernez, M; Hughes, J; Kibblewhite, H; Melchini, A; Mills, RD; Mithen, RF; Mythen, L; Needs, PW; O'Neill, CM; Saha, S; Savva, GM; Traka, MH; Troncoso-Rey, P | 1 |
| Gharabaghi, N; Gross, W; Hackert, T; Herr, I; Lozanovski, VJ; Mehrabi, A; Polychronidis, G; Schemmer, P | 1 |
| Cheskin, LJ; Cornblatt, BS; Cornblatt, G; Fahey, JW; Fuchs, E; Holtzclaw, WD; Liu, H; Ownby, SL; Panjwani, AA; Stephenson, KK; Wade, KL | 1 |
| Chiewchan, N; Devahastin, S; Pongmalai, P; Sangkret, S | 1 |
| Ball, RY; Beasy, G; Coode-Bate, J; Dainty, JR; Maicha, JB; Melchini, A; Mills, RD; Mithen, RF; Needs, PW; Saha, S; Sivapalan, T; Traka, MH | 1 |
| Liu, C; Wei, L; Zheng, H; Zheng, L | 1 |
| Hashimoto, K | 1 |
| AbdElgawad, H; Al Jaouni, SK; Almuhayawi, MS; Hassan, AHA; Khamis, G; Selim, S | 1 |
| Abukhabta, S; Allwood, JW; Charalampopoulos, D; Gill, CIR; Karatzas, KA; Khalil Ghawi, S; Latimer, C; Lavery, S; Lawther, R; McDougall, G; O'Connor, G; Pourshahidi, LK; Rowland, I; Verrall, S | 1 |
| Guo, L; Wang, F; Xiao, J; Xu, K; Zhu, Y; Zhuang, L | 1 |
| Chengzhi, L; Jianwei, M; Juan, S; Ligen, Z; Xinjie, S; Yao, Z; Yuanfeng, W | 1 |
| Augustin, MA; Jegasothy, H; Shokri, S; Terefe, NS | 1 |
| Hu, Q; Li, X; Liu, J; Lu, Y; Pang, X; Sun, J; Tian, S; Wang, J; Wang, Y | 1 |
| Del Río, R; González, F; Mahn, A; Quintero, J | 1 |
| Dayarathne, LA; Dinh, DTT; Han, CH; Jee, Y; Mihindukulasooriya, SP; Natraj, P; Rajan, P; Ranaweera, SS | 1 |
| Chang, L; Hashimoto, K; Liu, G; Wang, X; Wei, Y; Yang, Y | 1 |
| Bao, J; Li, S; Lu, X; Lu, Y; Ma, L; Ma, S; Shi, X; Tian, P; Wei, Y; Yang, J; Zhang, C; Zhang, X | 1 |
| Chen, W; Cui, S; Guo, W; Jin, Y; Lu, W; Mao, B; Tang, X; Wu, J; Zhang, Q; Zhao, J | 1 |
| Armstrong, E; Bowen-Forbes, C; Fahlman, R; Koosha, H; Moses, A; Yager, JY | 1 |
10 review(s) available for sulforaphane and glucoraphanin
| Article | Year |
|---|---|
Natural sulforaphane as a functional chemopreventive agent: including a review of isolation, purification and analysis methods.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Biotechnology; Cells, Cultured; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Oximes; Sulfoxides; Thiocyanates | 2012 |
Novel concepts of broccoli sulforaphanes and disease: induction of phase II antioxidant and detoxification enzymes by enhanced-glucoraphanin broccoli.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Brassica; Enzyme Induction; Glucosinolates; Humans; Imidoesters; Isothiocyanates; NAD(P)H Dehydrogenase (Quinone); Oximes; Sulfoxides; Thiocyanates | 2012 |
Sulforaphane as a potential protective phytochemical against neurodegenerative diseases.
Topics: Animals; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Oximes; Sulfoxides; Thiocyanates | 2013 |
Clinical and molecular evidence of the consumption of broccoli, glucoraphanin and sulforaphane in humans.
Topics: Anticarcinogenic Agents; Brassica; Diet; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Myocardial Infarction; Neoplasms; Oximes; Sulfoxides | 2014 |
Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism.
Topics: Brassica; Diet; Glucosinolates; Humans; Hypothyroidism; Imidoesters; Indoles; Iodine; Isothiocyanates; Oxazolidinones; Oximes; Plant Extracts; Sulfoxides; Thiocyanates; Thyroid Gland; Thyroid Hormones; Vegetables | 2016 |
Frugal chemoprevention: targeting Nrf2 with foods rich in sulforaphane.
Topics: Animals; Anticarcinogenic Agents; Brassica; Chemoprevention; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Neoplasms; NF-E2-Related Factor 2; Oximes; Signal Transduction; Sulfoxides; Vegetables | 2016 |
Antioxidant dietary approach in treatment of fatty liver: New insights and updates.
Topics: Animals; Anthocyanins; Antioxidants; Carotenoids; Catechin; Coumestrol; Curcumin; Energy Metabolism; Fatty Liver; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Lipogenesis; Mitochondria; Non-alcoholic Fatty Liver Disease; Nutritional Sciences; Oxidative Stress; Oximes; Polyphenols; Quercetin; Resveratrol; Stilbenes; Sulfoxides; Xanthophylls | 2017 |
Isothiocyanate from Broccoli, Sulforaphane, and Its Properties.
Topics: Animals; Antineoplastic Agents, Phytogenic; Autistic Disorder; Brassica; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Neoplasms; Osteoporosis; Oximes; Sulfoxides | 2019 |
Approaches for enhancing the stability and formation of sulforaphane.
Topics: Bacteria; Bacterial Proteins; Brassica; Cooking; Drug Stability; Glucosinolates; Glycoside Hydrolases; Hydrolysis; Imidoesters; Isothiocyanates; Oximes; Pressure; Sulfoxides | 2021 |
The effect of processing and cooking on glucoraphanin and sulforaphane in brassica vegetables.
Topics: Brassica; Cooking; Glucosinolates; Humans; Isothiocyanates; Microwaves; Oximes; Sulfoxides | 2021 |
13 trial(s) available for sulforaphane and glucoraphanin
| Article | Year |
|---|---|
Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli.
Topics: Adult; Anticarcinogenic Agents; Biological Availability; Brassica; Chromatography, High Pressure Liquid; Cooking; Cross-Over Studies; Glucose; Glucosinolates; Glycoside Hydrolases; Humans; Imidoesters; Intestinal Absorption; Isothiocyanates; Male; Middle Aged; Oximes; Sulfoxides; Thiocyanates | 2000 |
Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, China.
Topics: Adult; Aged; Anticarcinogenic Agents; Beverages; Biological Availability; Brassica; China; Cross-Over Studies; Female; Genotype; Glucosinolates; Glycoside Hydrolases; Humans; Imidoesters; Isothiocyanates; Male; Middle Aged; Oximes; Raphanus; Reproducibility of Results; Signal Transduction; Sulfhydryl Compounds; Sulfoxides; Thiocyanates; Treatment Outcome | 2011 |
Enhancing sulforaphane absorption and excretion in healthy men through the combined consumption of fresh broccoli sprouts and a glucoraphanin-rich powder.
Topics: Absorption; Acetylcysteine; Adolescent; Adult; Anticarcinogenic Agents; Biomarkers; Brassica; Cross-Over Studies; Diet; Dietary Supplements; Glucosinolates; Humans; Hydrolysis; Imidoesters; Isothiocyanates; Male; Neoplasms; Nutritional Sciences; Oximes; Powders; Sulfoxides; Surveys and Questionnaires; Young Adult | 2012 |
Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China.
Topics: Acetylcysteine; Acrolein; Adult; Air Pollutants; Aldehydes; Benzene; Beverages; Biomarkers; Brassica; China; DNA Adducts; Ethylene Oxide; Female; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Male; Middle Aged; Oximes; Polycyclic Aromatic Hydrocarbons; Smoking; Sulfoxides; Thiocyanates | 2012 |
Isothiocyanate concentrations and interconversion of sulforaphane to erucin in human subjects after consumption of commercial frozen broccoli compared to fresh broccoli.
Topics: Adult; Aged; Anticarcinogenic Agents; Biological Availability; Brassica; Cross-Over Studies; Female; Food Handling; Freezing; Gastrointestinal Tract; Glucosinolates; Glycoside Hydrolases; Humans; Imidoesters; Isothiocyanates; Kinetics; Male; Metagenome; Middle Aged; Oximes; Sulfides; Sulfoxides; Thiocyanates; Young Adult | 2012 |
In vivo formation and bioavailability of isothiocyanates from glucosinolates in broccoli as affected by processing conditions.
Topics: Adult; Biological Availability; Brassica; Cross-Over Studies; Female; Glucosinolates; Glycoside Hydrolases; Healthy Volunteers; Humans; Imidoesters; Isothiocyanates; Male; Middle Aged; Oximes; Sulfoxides | 2014 |
Rapid and sustainable detoxication of airborne pollutants by broccoli sprout beverage: results of a randomized clinical trial in China.
Topics: Adult; Aged; Air Pollutants; Air Pollution; Beverages; Biological Availability; Biomarkers; Brassica; China; Chromatography, Liquid; Female; Genotype; Glucosinolates; Glutathione Transferase; Humans; Imidoesters; Isothiocyanates; Male; Mass Spectrometry; Middle Aged; Oximes; Polymorphism, Single Nucleotide; Sulfoxides; Time Factors; Young Adult | 2014 |
Bioavailability of Glucoraphanin and Sulforaphane from High-Glucoraphanin Broccoli.
Topics: Adolescent; Adult; Aged; Alleles; Biological Availability; Brassica; Cross-Over Studies; Diet; Double-Blind Method; Female; Genotype; Genotyping Techniques; Glucosinolates; Glycoside Hydrolases; Humans; Imidoesters; Isothiocyanates; Male; Middle Aged; Oximes; Plant Proteins; Sulfoxides; Tandem Mass Spectrometry; Young Adult | 2018 |
Supplementation of the Diet by Exogenous Myrosinase via Mustard Seeds to Increase the Bioavailability of Sulforaphane in Healthy Human Subjects after the Consumption of Cooked Broccoli.
Topics: Adolescent; Adult; Biological Availability; Brassica; Cooking; Creatinine; Cross-Over Studies; Diet; Glucosinolates; Glycoside Hydrolases; Humans; Imidoesters; Isothiocyanates; Middle Aged; Mustard Plant; Oximes; Powders; Protein Denaturation; Seeds; Sulfoxides; Vegetables; Young Adult | 2018 |
Absorption and metabolism of isothiocyanates formed from broccoli glucosinolates: effects of BMI and daily consumption in a randomised clinical trial.
Topics: Acetylcysteine; Adult; Aged; Anticarcinogenic Agents; Area Under Curve; Body Mass Index; Brassica; Cooking; Cross-Over Studies; Diet; Female; Genotype; Glucose; Glucosinolates; Glutathione Transferase; Glycoside Hydrolases; Humans; Imidoesters; Isothiocyanates; Male; Mannitol; Middle Aged; Oximes; Raphanus; Sulfides; Sulfoxides; Tandem Mass Spectrometry; Thiocyanates | 2018 |
Transcriptional changes in prostate of men on active surveillance after a 12-mo glucoraphanin-rich broccoli intervention-results from the Effect of Sulforaphane on prostate CAncer PrEvention (ESCAPE) randomized controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brassica; Gene Expression; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Male; Middle Aged; Oximes; Prostate; Prostatic Neoplasms; Sulfoxides; Transcription, Genetic; Young Adult | 2019 |
Broccoli sprout supplementation in patients with advanced pancreatic cancer is difficult despite positive effects-results from the POUDER pilot study.
Topics: Aged; Biological Products; Brassica; Carcinoma, Pancreatic Ductal; Dietary Supplements; Female; Glucosinolates; Humans; Isothiocyanates; Male; Middle Aged; Oximes; Pancreatic Neoplasms; Pilot Projects; Prospective Studies; Sulfoxides; Survival Rate | 2020 |
Bioavailability of Sulforaphane Following Ingestion of Glucoraphanin-Rich Broccoli Sprout and Seed Extracts with Active Myrosinase: A Pilot Study of the Effects of Proton Pump Inhibitor Administration.
Topics: Adult; Aged; Biological Availability; Brassica; Dietary Supplements; Drug Interactions; Female; Gastric Acid; Gene Expression Regulation; Glucosinolates; Glycoside Hydrolases; Humans; Hydrogen-Ion Concentration; Imidoesters; Isothiocyanates; Leukocytes, Mononuclear; Male; Middle Aged; Omeprazole; Oximes; Pilot Projects; Plant Extracts; Proton Pump Inhibitors; Seedlings; Seeds; Sulfoxides; Young Adult | 2019 |
55 other study(ies) available for sulforaphane and glucoraphanin
| Article | Year |
|---|---|
Formation of glucoraphanin by chemoselective oxidation of natural glucoerucin: a chemoenzymatic route to sulforaphane.
Topics: Catalysis; Chromatography, High Pressure Liquid; Glucose; Glucosinolates; Glycoside Hydrolases; Imidoesters; Isothiocyanates; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Oximes; Sulfoxides; Thiocyanates | 1999 |
Comparison of the bioactivity of two glucoraphanin hydrolysis products found in broccoli, sulforaphane and sulforaphane nitrile.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Brassica; Colon; Glucose; Glucosinolates; Glutathione Transferase; Hydrolysis; Hydroquinones; Imidoesters; Isothiocyanates; Liver; Male; NAD(P)H Dehydrogenase (Quinone); Nitriles; Oximes; Pancreas; Rats; Rats, Inbred F344; Sulfoxides; Thiocyanates | 2001 |
Heating decreases epithiospecifier protein activity and increases sulforaphane formation in broccoli.
Topics: Animals; Anticarcinogenic Agents; Brassica; Cell Line, Tumor; Glucose; Glucosinolates; Heating; Imidoesters; Isothiocyanates; Mice; Oximes; Plant Proteins; Plant Shoots; Sulfoxides; Temperature; Thiocyanates | 2004 |
Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver.
Topics: Animals; Anticarcinogenic Agents; Biomarkers; Blotting, Northern; Blotting, Western; Brassica; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dietary Supplements; Electron Spin Resonance Spectroscopy; Fluorometry; Free Radicals; Glucose; Glucosinolates; Imidoesters; Isothiocyanates; Liver; Metabolic Detoxication, Phase I; Metabolic Detoxication, Phase II; Molecular Probes; Oximes; Rats; Rats, Sprague-Dawley; Sulfoxides; Thiocyanates; Xenobiotics | 2006 |
[Sulforaphane (1-isothiocyanato-4-(methylsulfinyl)-butane) content in cruciferous vegetables].
Topics: Anticarcinogenic Agents; Brassica; Chromatography, High Pressure Liquid; Glucosinolates; Imidoesters; Isothiocyanates; Oximes; Plant Leaves; Sulfoxides; Thiocyanates; Vegetables | 2009 |
HPLC method validation for measurement of sulforaphane level in broccoli by-products.
Topics: Brassica; Chromatography, High Pressure Liquid; Glucosinolates; Hydrogen-Ion Concentration; Imidoesters; Isothiocyanates; Oximes; Reproducibility of Results; Solid Phase Extraction; Sulfoxides; Thiocyanates | 2010 |
The impact of loss of myrosinase on the bioactivity of broccoli products in F344 rats.
Topics: Animals; Biological Availability; Brassica; Colon; Food Handling; Gene Expression; Glucosinolates; Glycoside Hydrolases; Hydrolysis; Imidoesters; Isothiocyanates; Liver; Male; NAD(P)H Dehydrogenase (Quinone); Oximes; Plant Extracts; Rats; Rats, Inbred F344; Seeds; Sulfoxides; Thiocyanates | 2010 |
Up-regulation of cytochrome P450 and phase II enzyme systems in rat precision-cut rat lung slices by the intact glucosinolates, glucoraphanin and glucoerucin.
Topics: Animals; Anticarcinogenic Agents; Cytochrome P-450 Enzyme System; Dealkylation; Glucose; Glucosinolates; Glutathione; Glutathione Transferase; Glycoside Hydrolases; Imidoesters; In Vitro Techniques; Isothiocyanates; Lung; Male; Metabolic Detoxication, Phase II; Oxazines; Oximes; Rats; Rats, Wistar; Sulfides; Sulfoxides; Thiocyanates; Up-Regulation | 2011 |
Breakdown products of neoglucobrassicin inhibit activation of Nrf2 target genes mediated by myrosinase-derived glucoraphanin hydrolysis products.
Topics: Benzo(a)pyrene; Brassica; Cell Line, Tumor; Gene Expression Regulation; Glucosinolates; Glutathione Peroxidase; Glycoside Hydrolases; Hep G2 Cells; Humans; Hydrolysis; Imidoesters; Indoles; Isothiocyanates; Mutagenesis, Site-Directed; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oximes; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Sulfoxides; Thiocyanates; Transcriptional Activation; Xenobiotics | 2010 |
Induction of epoxide hydrolase and glucuronosyl transferase by isothiocyanates and intact glucosinolates in precision-cut rat liver slices: importance of side-chain substituent and chirality.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Induction; Epoxide Hydrolases; Glucose; Glucosinolates; Glucuronosyltransferase; Imidoesters; Isothiocyanates; Liver; Male; Oximes; Rats; Rats, Wistar; Stereoisomerism; Sulfides; Sulfoxides; Thiocyanates | 2011 |
Sulforaphane absorption and excretion following ingestion of a semi-purified broccoli powder rich in glucoraphanin and broccoli sprouts in healthy men.
Topics: Adolescent; Adult; Biological Transport; Brassica; Cross-Over Studies; Diet; Eating; Glucosinolates; Glycoside Hydrolases; Humans; Hydrolysis; Imidoesters; Isothiocyanates; Male; Nutritional Physiological Phenomena; Oximes; Sulfoxides; Surveys and Questionnaires; Thiocyanates; Young Adult | 2011 |
Glucoraphanin hydrolysis by microbiota in the rat cecum results in sulforaphane absorption.
Topics: Animals; Brassica; Cecum; Digestion; Enterocytes; Enzymes; Glucosinolates; Hydrogen-Ion Concentration; Hydrolysis; Imidoesters; Intestinal Absorption; Isothiocyanates; Male; Metagenome; Oximes; Rats; Rats, Inbred F344; Sulfoxides; Thiocyanates | 2010 |
Comparison of isothiocyanate metabolite levels and histone deacetylase activity in human subjects consuming broccoli sprouts or broccoli supplement.
Topics: Adult; Brassica; Diet; Dietary Supplements; Female; Glucose; Glucosinolates; Histone Deacetylases; Humans; Imidoesters; Isothiocyanates; Male; Middle Aged; Oximes; Plant Shoots; Sulfides; Sulfoxides; Thiocyanates | 2011 |
Physiological and biochemical metabolism of germinating broccoli seeds and sprouts.
Topics: Brassica; Germination; Glucosinolates; Imidoesters; Isothiocyanates; Oximes; Plant Extracts; Seeds; Sulfoxides; Thiocyanates | 2012 |
Simultaneous determination of glucoraphanin and sulforaphane in Brassica oleracea seeds by high-performance liquid chromatography with evaporative light-scattering detector.
Topics: Brassica; Chromatography, High Pressure Liquid; Glucosinolates; Imidoesters; Isothiocyanates; Light; Oximes; Plant Extracts; Scattering, Radiation; Seeds; Sulfoxides; Thiocyanates | 2013 |
The potential to intensify sulforaphane formation in cooked broccoli (Brassica oleracea var. italica) using mustard seeds (Sinapis alba).
Topics: Brassica; Cooking; Glucosinolates; Hot Temperature; Imidoesters; Isothiocyanates; Mustard Plant; Oximes; Seeds; Sulfoxides; Thiocyanates | 2013 |
A derivatization method for the simultaneous detection of glucosinolates and isothiocyanates in biological samples.
Topics: Animals; Chromatography, High Pressure Liquid; Cystine; Feces; Glucose; Glucosinolates; Hydrolysis; Imidoesters; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; Oximes; Sulfides; Sulfoxides; Thiocyanates | 2013 |
Modifying the processing and handling of frozen broccoli for increased sulforaphane formation.
Topics: Anticarcinogenic Agents; Brassica; Food Additives; Food Handling; Freezing; Glucosinolates; Glycoside Hydrolases; Hot Temperature; Imidoesters; Isothiocyanates; Lipoxygenase; Microwaves; Oximes; Raphanus; Sulfoxides | 2013 |
Sulforaphane is superior to glucoraphanin in modulating carcinogen-metabolising enzymes in Hep G2 cells.
Topics: Anticarcinogenic Agents; Carcinoma, Hepatocellular; Glucosinolates; Glutathione Transferase; Glycoside Hydrolases; Humans; Imidoesters; Isothiocyanates; Liver Neoplasms; NAD(P)H Dehydrogenase (Quinone); Oximes; Sulfoxides; Tumor Cells, Cultured | 2013 |
Influence of seasonal variation and methyl jasmonate mediated induction of glucosinolate biosynthesis on quinone reductase activity in broccoli florets.
Topics: Acetates; Brassica; Cyclopentanes; Glucosinolates; Hydrolysis; Imidoesters; Indoles; Isothiocyanates; NAD(P)H Dehydrogenase (Quinone); Oximes; Oxylipins; Plant Proteins; Seasons; Sulfoxides | 2013 |
A new ultra-rapid UHPLC/MS/MS method for assessing glucoraphanin and sulforaphane bioavailability in human urine.
Topics: Adult; Biological Availability; Brassica; Chromatography, High Pressure Liquid; Female; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Male; Oximes; Plant Extracts; Sulfoxides; Tandem Mass Spectrometry | 2014 |
Optimization of a blanching step to maximize sulforaphane synthesis in broccoli florets.
Topics: Brassica; Food Handling; Glucosinolates; Glycoside Hydrolases; Hot Temperature; Imidoesters; Isothiocyanates; Oximes; Sulfoxides | 2014 |
The metabolism of methylsulfinylalkyl- and methylthioalkyl-glucosinolates by a selection of human gut bacteria.
Topics: Brassica; Cell-Free System; Enterococcus; Escherichia coli; Gastrointestinal Tract; Glucose; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Lactobacillus; Oximes; Sulfides; Sulfoxides; Thiocyanates | 2014 |
Effect of NaCl stress on health-promoting compounds and antioxidant activity in the sprouts of three broccoli cultivars.
Topics: Antioxidants; Ascorbic Acid; Brassica; China; Down-Regulation; Functional Food; Glucosinolates; Glycoside Hydrolases; Imidoesters; Isothiocyanates; Oximes; Phenols; Plant Proteins, Dietary; Plant Shoots; Salinity; Species Specificity; Stress, Physiological; Sulfoxides; Up-Regulation | 2014 |
Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancer differently.
Topics: Animals; Anticarcinogenic Agents; Basic Helix-Loop-Helix Transcription Factors; Brassica; Colon; Colonic Neoplasms; Cytochrome P-450 CYP1A1; Diet; Glucosinolates; Glutathione Peroxidase; Glutathione Transferase; Imidoesters; Indoles; Inflammation; Isothiocyanates; Lysine; Male; Mice; Mice, Inbred C57BL; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidoreductases Acting on Sulfur Group Donors; Oximes; Plant Extracts; Receptors, Aryl Hydrocarbon; Sulfoxides; Vegetables | 2014 |
Novel gram-scale production of enantiopure R-sulforaphane from Tuscan black kale seeds.
Topics: Brassica; Glucosinolates; Glycoside Hydrolases; Imidoesters; Isothiocyanates; Oximes; Seeds; Sulfoxides | 2014 |
Isothiocyanate metabolism, distribution, and interconversion in mice following consumption of thermally processed broccoli sprouts or purified sulforaphane.
Topics: Animals; Anticarcinogenic Agents; Brassica; Dietary Supplements; Female; Food Handling; Freeze Drying; Functional Food; Glucose; Glucosinolates; Hot Temperature; Imidoesters; Isothiocyanates; Kidney; Liver; Mice, Hairless; Organ Specificity; Oximes; Plant Shoots; Sulfides; Sulfoxides; Thiocyanates; Urinary Bladder; Weight Gain | 2014 |
The intake of broccoli sprouts modulates the inflammatory and vascular prostanoids but not the oxidative stress-related isoprostanes in healthy humans.
Topics: Adult; Ascorbic Acid; Biomarkers; Brassica; Chromatography, High Pressure Liquid; Cross-Over Studies; Female; Glucosinolates; Healthy Volunteers; Humans; Imidoesters; Inflammation; Isoprostanes; Isothiocyanates; Male; Middle Aged; Oxidative Stress; Oximes; Plant Extracts; Prostaglandins; Sulfoxides; Tandem Mass Spectrometry; Thromboxane B2; Vascular Diseases; White People; Young Adult | 2015 |
Myrosinase-treated glucoerucin is a potent inducer of the Nrf2 target gene heme oxygenase 1--studies in cultured HT-29 cells and mice.
Topics: Animals; Brain; Diet, High-Fat; Female; Glucose; Glucosinolates; Glycoside Hydrolases; Heme Oxygenase-1; HT29 Cells; Humans; Imidoesters; Intestinal Mucosa; Intestines; Isothiocyanates; Liver; Membrane Proteins; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 3; Mustard Plant; NF-E2-Related Factor 2; Oximes; p38 Mitogen-Activated Protein Kinases; Plant Extracts; RNA, Messenger; Signal Transduction; Sulfoxides; Up-Regulation | 2015 |
A Glance at… Broccoli, glucoraphanin, and sulforaphane.
Topics: Anti-Inflammatory Agents; Antioxidants; Brassica; Diet; Glucose; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Oximes; Sulfoxides | 2015 |
Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase.
Topics: Adult; Biological Availability; Brassica; Dietary Supplements; Drug Delivery Systems; Female; Glucosinolates; Glycoside Hydrolases; Humans; Imidoesters; Isothiocyanates; Male; Middle Aged; Oximes; Plant Extracts; Seedlings; Seeds; Sulfoxides | 2015 |
Prophylactic effects of sulforaphane on depression-like behavior and dendritic changes in mice after inflammation.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Brassica; Depression; Disease Models, Animal; Disks Large Homolog 4 Protein; Glucosinolates; Imidoesters; Inflammation; Interleukin-10; Isothiocyanates; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Oximes; Receptors, AMPA; Sulfoxides; Tumor Necrosis Factor-alpha | 2017 |
Stabilized sulforaphane for clinical use: Phytochemical delivery efficiency.
Topics: alpha-Cyclodextrins; Animals; Anticarcinogenic Agents; Biological Availability; Brassica; Dietary Supplements; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Mice; Oximes; Phytochemicals; Sulfoxides; Thiocyanates | 2017 |
Microwave heating modelling of a green smoothie: Effects on glucoraphanin, sulforaphane and S-methyl cysteine sulfoxide changes during storage.
Topics: Color; Cysteine; Food Handling; Food Storage; Fruit; Fruit and Vegetable Juices; Glucosinolates; Hot Temperature; Imidoesters; Isothiocyanates; Microwaves; Oximes; Sulfoxides; Vegetables | 2018 |
Bioavailability of Isothiocyanates From Broccoli Sprouts in Protein, Lipid, and Fiber Gels.
Topics: Adult; Body Mass Index; Brassica; Cross-Over Studies; Dietary Fats; Dietary Fiber; Dietary Proteins; Female; Gels; Glucosinolates; Glycoproteins; Humans; Imidoesters; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Male; Middle Aged; Oximes; Plant Proteins; Powders; Sulfoxides; Young Adult | 2018 |
Kinetic and structural study of broccoli myrosinase and its interaction with different glucosinolates.
Topics: Amino Acid Sequence; Binding Sites; Brassica; DNA, Complementary; Glucosinolates; Glycoside Hydrolases; Humans; Hydrolysis; Imidoesters; Isothiocyanates; Kinetics; Molecular Docking Simulation; Oximes; Sulfoxides | 2018 |
Effects of α-, β- and maltosyl-β-cyclodextrins use on the glucoraphanin-sulforaphane system of broccoli juice.
Topics: alpha-Cyclodextrins; beta-Cyclodextrins; Brassica; Food Additives; Fruit and Vegetable Juices; gamma-Cyclodextrins; Glucosinolates; Imidoesters; Isothiocyanates; Maillard Reaction; Oximes; Plant Extracts; Sulfoxides | 2019 |
Glucoraphanin and sulforaphane evolution during juice preparation from broccoli sprouts.
Topics: Brassica; Food Handling; Fruit and Vegetable Juices; Glucosinolates; Imidoesters; Isothiocyanates; Oximes; Sulfoxides | 2018 |
Effect of glucoraphanin and sulforaphane against chemotherapy-induced neuropathic pain: Kv7 potassium channels modulation by H
Topics: Animals; Antineoplastic Agents; Glucosinolates; Hydrogen Sulfide; Imidoesters; Isothiocyanates; KCNQ1 Potassium Channel; Male; Mice; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Oximes; Sulfoxides | 2018 |
Slightly Acidic Electrolyzed Water Treatment Enhances the Main Bioactive Phytochemicals Content in Broccoli Sprouts via Changing Metabolism.
Topics: Anthocyanins; Brassica; Electrolysis; Germination; Glucosinolates; Hydrogen-Ion Concentration; Imidoesters; Isothiocyanates; Oximes; Phytochemicals; Seeds; Sulfoxides; Water | 2019 |
Transcriptome reveals the gene expression patterns of sulforaphane metabolism in broccoli florets.
Topics: Anticarcinogenic Agents; Brassica; Cytochrome P-450 Enzyme System; Flowers; Gene Expression Regulation, Plant; Genes, Plant; Glucosinolates; Imidoesters; Isothiocyanates; Metabolic Networks and Pathways; Oximes; Plant Growth Regulators; Plant Proteins; Sulfoxides; Transcriptome | 2019 |
Enhanced production of sulforaphane by exogenous glucoraphanin hydrolysis catalyzed by myrosinase extracted from Chinese flowering cabbage (Brassica rapa var. parachinensis).
Topics: Brassica rapa; Catalysis; Glucosinolates; Glycoside Hydrolases; Hydrolysis; Imidoesters; Isothiocyanates; Oximes; Sulfoxides; Vegetables | 2019 |
Accumulation of Dietary S-Methyl Cysteine Sulfoxide in Human Prostate Tissue.
Topics: Aged; Allium; Brassica; Dietary Supplements; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Male; Middle Aged; Oximes; Prostate; Prostatic Neoplasms; Single-Blind Method; Sulfoxides | 2019 |
Melatonin treatment affects the glucoraphanin-sulforaphane system in postharvest fresh-cut broccoli (Brassica oleracea L.).
Topics: Brassica; Food Handling; Gene Expression Regulation, Plant; Glucosinolates; Imidoesters; Isothiocyanates; Melatonin; Metabolic Networks and Pathways; Oximes; Sulfoxides | 2020 |
Risk of neuropsychiatric disorders in offspring of COVID-19-infected pregnant women and nutritional intervention.
Topics: Autism Spectrum Disorder; C-Reactive Protein; COVID-19; Dietary Supplements; Female; Gestational Age; Glucosinolates; Humans; Imidoesters; Infectious Disease Transmission, Vertical; Inflammation; Isothiocyanates; Oximes; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; SARS-CoV-2; Schizophrenia; Sulfoxides | 2021 |
Elevated CO
Topics: Amino Acids; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Brassica; Carbon Dioxide; Cell Line; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Oximes; Plant Extracts; Sulfoxides | 2020 |
Sulforaphane-enriched extracts from glucoraphanin-rich broccoli exert antimicrobial activity against gut pathogens in vitro and innovative cooking methods increase in vivo intestinal delivery of sulforaphane.
Topics: Anti-Infective Agents; Brassica; Cooking; Cross-Over Studies; Glucosinolates; Humans; Isothiocyanates; Oximes; Plant Extracts; Sulfoxides | 2021 |
Calcium affects glucoraphanin metabolism in broccoli sprouts under ZnSO
Topics: Brassica; Calcium Chloride; Egtazic Acid; Glucosinolates; Glycoside Hydrolases; Hydrolysis; Imidoesters; Isothiocyanates; Malondialdehyde; Oximes; Plant Proteins; Seedlings; Stress, Physiological; Sulfoxides; Zinc Sulfate | 2021 |
Thermosonication for the Production of Sulforaphane Rich Broccoli Ingredients.
Topics: Biomass; Brassica; Cell Wall; Dietary Supplements; Food Handling; Food Technology; Glucosinolates; Glycoside Hydrolases; Hot Temperature; Isothiocyanates; Oximes; Polyphenols; Sonication; Sulfoxides; Temperature | 2021 |
Optimization of an Extraction Process to Obtain a Food-Grade Sulforaphane-Rich Extract from Broccoli (
Topics: Brassica; Chemical Fractionation; Ethanol; Glucosinolates; Isothiocyanates; Oximes; Plant Extracts; Sulfoxides | 2021 |
Anti-obesity effect of sulforaphane in broccoli leaf extract on 3T3-L1 adipocytes and ob/ob mice.
Topics: 3T3-L1 Cells; Adipocytes; Adipocytes, White; AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; Blood Glucose; Brassica; Glucose; Glucosinolates; Isothiocyanates; Lipid Metabolism; Lipids; Liver; Male; Mice; Mice, Obese; Obesity; Oximes; Phosphorylation; Plant Extracts; Plant Leaves; Sulfoxides; Transcriptome; Triglycerides | 2022 |
Long-lasting beneficial effects of maternal intake of sulforaphane glucosinolate on gut microbiota in adult offspring.
Topics: Adult Children; Female; Gastrointestinal Microbiome; Glucosinolates; Humans; Interleukin-6; Isothiocyanates; Lipopolysaccharides; Male; Oximes; Pregnancy; Sulfoxides; Tumor Necrosis Factor-alpha | 2022 |
Transcriptome analysis of genes related to glucoraphanin and sulforaphane synthesis in methyl jasmonate treated broccoli (Brassica oleracea var. italica) hairy roots.
Topics: Brassica; Gene Expression Profiling | 2022 |
Broccoli seed extract rich in polysaccharides and glucoraphanin ameliorates DSS-induced colitis via intestinal barrier protection and gut microbiota modulation in mice.
Topics: Animals; Anti-Inflammatory Agents; Brassica; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Mice; Mice, Inbred C57BL; Plant Extracts; Polysaccharides | 2023 |
Broccoli, Kale, and Radish Sprouts: Key Phytochemical Constituents and DPPH Free Radical Scavenging Activity.
Topics: Brassica; Free Radicals; Glucosinolates; Isothiocyanates; Raphanus | 2023 |