Page last updated: 2024-08-16

sulforaphane and fluorouracil

sulforaphane has been researched along with fluorouracil in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's6 (50.00)24.3611
2020's5 (41.67)2.80

Authors

AuthorsStudies
Chen, X; Hu, K; Jiang, HF; Qi, YJ; Ren, J; Zhao, J1
Li, BX; Lu, YJ; Wang, XF; Wu, DM; Yang, BF1
Ferruzzi, L; Fimognari, C; Turrini, E1
Chilmonczyk, Z; Dąbrowska, A; Koronkiewicz, M; Lubelska, K; Matosiuk, D; Mielczarek, L; Milczarek, M; Wiktorska, K1
Bjørklund, G; Chirumbolo, S1
Ashry, R; Elghanam, GA; Elkashty, OA; Pham, HM; Stegen, C; Su, X; Tran, SD1
Chilmonczyk, Z; Dąbrowska, A; Lubelska, K; Matosiuk, D; Mielczarek, L; Milczarek, M; Wiktorska, K1
Milczarek, M; Pogorzelska, A; Wiktorska, K1
Afzal, O; Akhter, MH; Al-Abbasi, FA; Alharbi, KS; Almalki, WH; Alrobaian, M; Altamimi, ASA; Altowayan, WM; Beg, S; Gupta, M; Kazmi, I; Li, S; Rahman, M; Singh, T; Xu, Z1
Baušys, A; Bruns, H; Čekauskas, A; Čižauskaitė, A; Herr, I; Kallifatidis, G; Schemmer, P; Schultze, D; Šimčikas, D; Strupas, K1
Blazev, R; Li, W; Lynch, GS; Murphy, KT; Parker, BL; Swiderski, K; Trieu, J1
Cierpiał, T; Kiełbasiński, P; Mazur, M; Małecka-Giełdowska, M; Milczarek, M; Świtalska, M; Wietrzyk, J; Wiktorska, K1

Reviews

1 review(s) available for sulforaphane and fluorouracil

ArticleYear
Natural compounds to overcome cancer chemoresistance: toxicological and clinical issues.
    Expert opinion on drug metabolism & toxicology, 2014, Volume: 10, Issue:12

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Curcumin; Drug Resistance, Neoplasm; Fluorouracil; Humans; Isothiocyanates; Neoplasms; Platinum Compounds; Signal Transduction; Sulfoxides

2014

Other Studies

11 other study(ies) available for sulforaphane and fluorouracil

ArticleYear
Synthesis and biological evaluation of sulforaphane derivatives as potential antitumor agents.
    European journal of medicinal chemistry, 2013, Volume: 64

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HCT116 Cells; Hep G2 Cells; Humans; Isothiocyanates; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship; Sulfoxides; Thiocyanates; Vero Cells

2013
Synergistic inhibitory effect of sulforaphane and 5-fluorouracil in high and low metastasis cell lines of salivary gland adenoid cystic carcinoma.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:3

    Topics: Anticarcinogenic Agents; Antimetabolites, Antineoplastic; Carcinoma, Adenoid Cystic; Cell Line, Tumor; Drug Combinations; Drug Synergism; Fluorouracil; Humans; Isothiocyanates; Salivary Gland Neoplasms; Sulfoxides; Thiocyanates; Transcription Factor RelA

2009
Autophagic cell death and premature senescence: New mechanism of 5-fluorouracil and sulforaphane synergistic anticancer effect in MDA-MB-231 triple negative breast cancer cell line.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 111

    Topics: Antineoplastic Agents; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Synergism; Female; Fluorouracil; Humans; Isothiocyanates; Sulfoxides

2018
Sulforaphane and 5-fluorouracil synergistically inducing autophagy in breast cancer: A possible role for the Nrf2-Keap1-ARE signaling?
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 112

    Topics: Autophagy; Breast Neoplasms; Fluorouracil; Humans; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Sulfoxides

2018
Broccoli extract improves chemotherapeutic drug efficacy against head-neck squamous cell carcinomas.
    Medical oncology (Northwood, London, England), 2018, Aug-04, Volume: 35, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; DNA Damage; Fluorouracil; Gene Expression; Head and Neck Neoplasms; Humans; Isothiocyanates; Male; Middle Aged; Plant Extracts; Squamous Cell Carcinoma of Head and Neck; Sulfoxides

2018
In Vitro Evaluation of Sulforaphane and a Natural Analog as Potent Inducers of 5-Fluorouracil Anticancer Activity.
    Molecules (Basel, Switzerland), 2018, Nov-21, Volume: 23, Issue:11

    Topics: Antineoplastic Agents; Caco-2 Cells; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytostatic Agents; Drug Synergism; Fluorouracil; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; In Vitro Techniques; Isothiocyanates; Neoplasms; Signal Transduction; Sulfoxides; Thiocyanates

2018
Synergistic Interaction between 5-FU and an Analog of Sulforaphane-2-Oxohexyl Isothiocyanate-In an In Vitro Colon Cancer Model.
    Molecules (Basel, Switzerland), 2021, May-19, Volume: 26, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Fluorouracil; Humans; In Vitro Techniques; Isothiocyanates; Models, Biological; Sulfoxides; Thiocyanates

2021
EGF-functionalized lipid-polymer hybrid nanoparticles of 5-fluorouracil and sulforaphane with enhanced bioavailability and anticancer activity against colon carcinoma.
    Biotechnology and applied biochemistry, 2022, Volume: 69, Issue:5

    Topics: Biological Availability; Carcinoma; Cell Survival; Colonic Neoplasms; Drug Carriers; Drug Delivery Systems; Epidermal Growth Factor; Fluorouracil; Humans; Lipids; Nanoparticles; Particle Size; Polymers

2022
Sulforaphane has an additive anticancer effect to FOLFOX in highly metastatic human colon carcinoma cells.
    Oncology reports, 2022, Volume: 48, Issue:5

    Topics: Aldehyde Dehydrogenase 1 Family; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neoplasms; Fluorouracil; Humans; Isothiocyanates; Leucovorin; Organoplatinum Compounds; Oxaliplatin; Sulfoxides

2022
Sulforaphane attenuates cancer cell-induced atrophy of C2C12 myotubes.
    American journal of physiology. Cell physiology, 2023, 02-01, Volume: 324, Issue:2

    Topics: Antioxidants; Dimethyl Sulfoxide; Fluorouracil; Humans; Muscle Fibers, Skeletal; Muscular Atrophy; Neoplasms; NF-E2-Related Factor 2; Oxidative Stress; Quality of Life

2023
An Organofluorine Isoselenocyanate Analogue of Sulforaphane Affects Antimetabolite 5-Fluorouracil's Anticancer Activity: A Perspective for New Combinatory Therapy in Triple-Negative Breast Cancer.
    Molecules (Basel, Switzerland), 2023, Aug-01, Volume: 28, Issue:15

    Topics: Animals; Antimetabolites; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Fluorouracil; Humans; Immunosuppressive Agents; Mice; Sulfoxides; Triple Negative Breast Neoplasms

2023