sulforaphane has been researched along with acetylcysteine in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (31.25) | 29.6817 |
| 2010's | 17 (53.13) | 24.3611 |
| 2020's | 5 (15.63) | 2.80 |
| Authors | Studies |
|---|---|
| Biswal, S; Hassan, M; Kumar, A; Kumar, S; Kumar, V; Malhotra, SV; Parmar, VS; Sharma, SK; Thimmulappa, RK; Wu, H | 1 |
| Hebbar, V; Hu, R; Keum, YS; Kim, BR; Kong, AN; Nair, SS; Shen, G | 1 |
| Antosiewicz, J; Choi, S; Herman-Antosiewicz, A; Johnson, CS; Lee, YJ; Lew, KL; Singh, SV; Srivastava, SK; Trump, DL; Watkins, SC; Xiao, D; Xiao, H; Zeng, Y | 1 |
| Hwang, ES; Jeffery, EH | 1 |
| Chung, FL; Conaway, CC; Hecht, SS; McIntee, EJ; Pittman, B; Schwartz, JE; Tian, D; Wang, CX; Yang, YM | 1 |
| Chen, C; Hebbar, V; Kong, AN; Shen, G; Xu, C | 1 |
| Li, G; Song, L; Tang, L; Zhang, Y | 1 |
| Al Janobi, AA; Barrett, DA; Gasper, AV; Middleton, RJ; Mithen, RF; Ortori, CA; Shaw, PN | 1 |
| Duncan, AJ; Fuller, Z; Ratcliffe, B; Rungapamestry, V | 1 |
| Sens, DA; Shavali, S | 1 |
| Barajas, B; Kim, HJ; Nel, AE; Wang, M | 1 |
| Gan, N; Mi, L; Sirajuddin, P; Wang, X | 1 |
| Cramer, JM; Jeffery, EH; Teran-Garcia, M | 1 |
| Carmella, SG; Chen, JG; Chen, M; Chen, TY; Egner, PA; Fahey, JW; Groopman, JD; Hecht, SS; Jacobson, LP; Kensler, TW; Muñoz, A; Ng, D; Qian, GS; Talalay, P; Yuan, JM | 1 |
| Lee, SH; Lee, YJ | 2 |
| Ahamed, M; Akhtar, MJ; Alrokayan, SA; Fareed, M; Kumar, S | 1 |
| Hunter, JJ; Sparrow, JR; Williams, DR; Yamamoto, K; Zhou, J | 1 |
| Jang, JH; Lee, C; Lee, SR; Park, GH | 1 |
| Blair, I; Gillespie, K; Koo, KA; Lorent, K; Marchione, DM; Pack, M; Porter, JR; Shin, D; So, J; Waisbourd-Zinman, O; Wells, RG; Wilkins, BJ; Zhao, X | 1 |
| Abramov, AY; Antoine, DJ; Aronica, E; Balosso, S; Del Giudice, E; Liang, LP; Pascente, R; Pastore, A; Patel, M; Pauletti, A; Ravizza, T; Rizzi, M; Salamone, A; Shekh-Ahmad, T; Terrone, G; van Vliet, EA; Vezzani, A; Villa, BR; Walker, MC | 1 |
| Bao, Y; Bowater, RP; Chen, Y; Liu, P; Smith, AJO; Wang, W; Wormstone, IM; Zhou, Z | 1 |
| Hu, Y; Li, J; Wang, Y; Wu, W; Yan, Y; Yang, G; Zheng, Z; Zhou, Y | 1 |
| Cui, HX; Du, J; Kang, L; Li, S; Liu, HJ; Wang, L | 1 |
| Charron, CS; Jeffery, EH; Novotny, JA; Ross, SA; Seifried, HE; Vinyard, BT | 1 |
| Abramov, AY; Aronica, E; Balosso, S; Del Giudice, E; Liang, LP; Pascente, R; Pastore, A; Patel, M; Pauletti, A; Ravizza, T; Rizzi, M; Salamone, A; Shekh-Ahmad, T; Terrone, G; van Vliet, EA; Vezzani, A; Villa, BR; Walker, MC | 1 |
| Bertini, ES; D'Amico, J; La Rosa, P; Petrillo, S; Piemonte, F | 1 |
| Hong, JH; Jeong, SH; Kim, SH; Kim, YJ; Kyung, SY; Park, JW; Son, ES | 1 |
| Chiang, S; Huang, MLH; Richardson, DR | 1 |
| Baba, ZA; Bhat, MA; Ganai, SA; Gani, M; Mohan, S; Padder, BA; Qadri, RA; Rajamanikandan, S; Shah, BA; Srinivasan, P; Yatoo, MA | 1 |
| Balosso, S; Bañuelos, I; Das Gupta, S; Hämäläinen, E; Hiltunen, M; Kajevu, N; Kyyriäinen, J; Lara, L; Lipponen, A; Natunen, T; Pitkänen, A; Puhakka, N; Ravizza, T; Vezzani, A | 1 |
| Bernuzzi, F; Bowater, RP; Huynh, TPN; Saha, S; Wormstone, IM | 1 |
4 trial(s) available for sulforaphane and acetylcysteine
| Article | Year |
|---|---|
Effect of meal composition and cooking duration on the fate of sulforaphane following consumption of broccoli by healthy human subjects.
Topics: Acetylcysteine; Adult; Brassica; Cooking; Diet; Diet, Vegetarian; Female; Glucosinolates; Glycoside Hydrolases; Humans; Isothiocyanates; Male; Meat; Nutritional Physiological Phenomena; Sulfoxides; Thiocyanates; Time Factors | 2007 |
Enhancing sulforaphane absorption and excretion in healthy men through the combined consumption of fresh broccoli sprouts and a glucoraphanin-rich powder.
Topics: Absorption; Acetylcysteine; Adolescent; Adult; Anticarcinogenic Agents; Biomarkers; Brassica; Cross-Over Studies; Diet; Dietary Supplements; Glucosinolates; Humans; Hydrolysis; Imidoesters; Isothiocyanates; Male; Neoplasms; Nutritional Sciences; Oximes; Powders; Sulfoxides; Surveys and Questionnaires; Young Adult | 2012 |
Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China.
Topics: Acetylcysteine; Acrolein; Adult; Air Pollutants; Aldehydes; Benzene; Beverages; Biomarkers; Brassica; China; DNA Adducts; Ethylene Oxide; Female; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Male; Middle Aged; Oximes; Polycyclic Aromatic Hydrocarbons; Smoking; Sulfoxides; Thiocyanates | 2012 |
Absorption and metabolism of isothiocyanates formed from broccoli glucosinolates: effects of BMI and daily consumption in a randomised clinical trial.
Topics: Acetylcysteine; Adult; Aged; Anticarcinogenic Agents; Area Under Curve; Body Mass Index; Brassica; Cooking; Cross-Over Studies; Diet; Female; Genotype; Glucose; Glucosinolates; Glutathione Transferase; Glycoside Hydrolases; Humans; Imidoesters; Isothiocyanates; Male; Mannitol; Middle Aged; Oximes; Raphanus; Sulfides; Sulfoxides; Tandem Mass Spectrometry; Thiocyanates | 2018 |
28 other study(ies) available for sulforaphane and acetylcysteine
| Article | Year |
|---|---|
Novel chalcone derivatives as potent Nrf2 activators in mice and human lung epithelial cells.
Topics: Animals; Bronchi; Cell Line; Cell Survival; Chalcones; Enzyme Activators; Epithelial Cells; Glutamate-Cysteine Ligase; Heme Oxygenase-1; Humans; Male; Mice; Mice, Inbred C57BL; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidation-Reduction; Quantitative Structure-Activity Relationship; Reactive Oxygen Species; Stereoisomerism; Transcription, Genetic | 2011 |
Effects of glutathione on antioxidant response element-mediated gene expression and apoptosis elicited by sulforaphane.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Buthionine Sulfoximine; Caspase 3; Caspases; Cell Line, Tumor; Enzyme Activation; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Isothiocyanates; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Response Elements; Sulfoxides; Thiocyanates | 2003 |
Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspase 8; Caspases; Cell Line, Tumor; Cells, Cultured; Cytochromes c; Enzyme Activation; Humans; Isothiocyanates; Male; Membrane Potentials; Mice; Mice, Knockout; Mitochondria; Models, Biological; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Sulfoxides; Thiocyanates | 2005 |
Induction of quinone reductase by sulforaphane and sulforaphane N-acetylcysteine conjugate in murine hepatoma cells.
Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Brassica; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Enzyme Induction; Glucosinolates; Isothiocyanates; Liver Neoplasms; NAD(P)H Dehydrogenase (Quinone); Phytotherapy; Sulfoxides; Thiocyanates; Tumor Cells, Cultured | 2005 |
Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.
Topics: Acetylcysteine; Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Body Weight; Carcinogens; Caspase 3; Caspases; Cell Growth Processes; Disease Progression; Female; In Situ Nick-End Labeling; Isothiocyanates; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Smoking; Sulfoxides; Thiocyanates | 2005 |
p53-independent G1 cell cycle arrest of human colon carcinoma cells HT-29 by sulforaphane is associated with induction of p21CIP1 and inhibition of expression of cyclin D1.
Topics: Acetylcysteine; Anticarcinogenic Agents; Blotting, Western; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Enzyme Activation; G1 Phase; Gene Expression; Glutathione; HT29 Cells; Humans; Isothiocyanates; Mitogen-Activated Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; Sulfoxides; Tetrazolium Salts; Thiocyanates; Time Factors; Tumor Suppressor Protein p53; Up-Regulation | 2006 |
The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells.
Topics: Acetylcysteine; Apoptosis; Cell Cycle; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Isothiocyanates; Sulfoxides; Thiocyanates; Urinary Bladder Neoplasms | 2006 |
Quantitative measurement of sulforaphane, iberin and their mercapturic acid pathway metabolites in human plasma and urine using liquid chromatography-tandem electrospray ionisation mass spectrometry.
Topics: Acetylcysteine; Chromatography, Liquid; Humans; Isothiocyanates; Molecular Structure; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Sulfoxides; Thiocyanates | 2006 |
Synergistic neurotoxic effects of arsenic and dopamine in human dopaminergic neuroblastoma SH-SY5Y cells.
Topics: Acetylcysteine; Anticarcinogenic Agents; Antioxidants; Arsenites; Cell Line, Tumor; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Drug Combinations; Drug Synergism; Humans; Isothiocyanates; Necrosis; Neuroblastoma; Neurons; Parkinson Disease; Sulfoxides; Thiocyanates | 2008 |
Nrf2 activation by sulforaphane restores the age-related decrease of T(H)1 immunity: role of dendritic cells.
Topics: Acetylcysteine; Adoptive Transfer; Aging; Animals; Dendritic Cells; Dermatitis, Contact; Female; Flow Cytometry; Free Radical Scavengers; Glutathione; Interferon-gamma; Interleukin-4; Isothiocyanates; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidation-Reduction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfoxides; Th1 Cells; Thiocyanates | 2008 |
A cautionary note on using N-acetylcysteine as an antagonist to assess isothiocyanate-induced reactive oxygen species-mediated apoptosis.
Topics: Acetylcysteine; Apoptosis; Carbon Isotopes; Cell Line, Tumor; HeLa Cells; Humans; Isothiocyanates; Reactive Oxygen Species; Sulfoxides; Thiocyanates | 2010 |
Sulforaphane induces antioxidative and antiproliferative responses by generating reactive oxygen species in human bronchial epithelial BEAS-2B cells.
Topics: Acetylcysteine; Anticarcinogenic Agents; Antioxidants; Bronchi; Cell Line; Cell Proliferation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Free Radical Scavengers; Heme Oxygenase-1; Humans; Isothiocyanates; NF-E2-Related Factor 2; Oxidative Stress; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Respiratory Mucosa; RNA Interference; RNA, Small Interfering; Signal Transduction; Sulfoxides; Thiocyanates | 2011 |
Protective effect of sulphoraphane against oxidative stress mediated toxicity induced by CuO nanoparticles in mouse embryonic fibroblasts BALB 3T3.
Topics: Acetylcysteine; Animals; Antioxidants; BALB 3T3 Cells; Cell Survival; Copper; Glutathione; Glutathione Reductase; Isothiocyanates; L-Lactate Dehydrogenase; Lipid Peroxidation; Mice; Microscopy, Electron, Transmission; Nanoparticles; Oxidative Stress; Reactive Oxygen Species; Sulfoxides; Thiocyanates | 2012 |
Toward an understanding of bisretinoid autofluorescence bleaching and recovery.
Topics: Acetylcysteine; Apoptosis; Cell Line; Chromatography, High Pressure Liquid; Fluorescence; Glutathione; Humans; Isothiocyanates; Light; Mass Spectrometry; Microscopy, Fluorescence; Pyridinium Compounds; Retinal Pigment Epithelium; Retinoids; Sulfoxides; Thiocyanates; Vitamin E | 2012 |
Attenuation of β-amyloid-induced oxidative cell death by sulforaphane via activation of NF-E2-related factor 2.
Topics: Acetylcysteine; Amyloid beta-Peptides; Antioxidants; Cell Death; Cell Line, Tumor; Gene Knockdown Techniques; Humans; Intracellular Space; Isothiocyanates; Models, Biological; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Signal Transduction; Sulfoxides | 2013 |
Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish.
Topics: Acetylcysteine; Animals; Animals, Genetically Modified; Benzodioxoles; Biliary Atresia; Disease Models, Animal; Glutathione; Hepatocytes; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Liver; NF-E2-Related Factor 2; Oxidation-Reduction; Sulfoxides; Zebrafish | 2016 |
Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.
Topics: Acetylcysteine; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Disease Models, Animal; Drug Therapy, Combination; Epilepsy; Hippocampus; HMG-Box Domains; HMGB1 Protein; Isothiocyanates; Male; Nerve Degeneration; Neurons; Oxidative Stress; Rats; Sulfoxides | 2017 |
Pro-oxidant activity of sulforaphane and cisplatin potentiates apoptosis and simultaneously promotes autophagy in malignant mesothelioma cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Autophagy; bcl-2-Associated X Protein; Cell Cycle Checkpoints; Cell Line, Tumor; Cisplatin; Glutathione; Humans; Isothiocyanates; Lung Neoplasms; Membrane Potential, Mitochondrial; Mesothelioma; Mesothelioma, Malignant; Microtubule-Associated Proteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Sulfoxides; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53; Up-Regulation | 2017 |
Chemopreventive Activities of Sulforaphane and Its Metabolites in Human Hepatoma HepG2 Cells.
Topics: Acetylcysteine; Anticarcinogenic Agents; Antioxidant Response Elements; Cell Adhesion; Cell Movement; Cell Survival; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Glutathione; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Isothiocyanates; NF-E2-Related Factor 2; Sulfoxides | 2018 |
Sulforaphane-N-Acetyl-Cysteine inhibited autophagy leading to apoptosis via Hsp70-mediated microtubule disruption.
Topics: Acetylcysteine; Aged; Anticarcinogenic Agents; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; HSP70 Heat-Shock Proteins; Humans; Isothiocyanates; Lung Neoplasms; Macrolides; Male; Microtubules; Middle Aged; Phenotype; Stathmin; Sulfoxides; Tissue Array Analysis; Tubulin | 2018 |
Sulforaphane-N-Acetyl-Cysteine Induces Autophagy Through Activation of ERK1/2 in U87MG and U373MG Cells.
Topics: Acetylcysteine; Anticarcinogenic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Databases, Factual; Flavonoids; G2 Phase Cell Cycle Checkpoints; Humans; Isothiocyanates; MAP Kinase Signaling System; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Proportional Hazards Models; RNA Interference; RNA, Small Interfering; Sulfoxides; Tubulin | 2018 |
Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.
Topics: Acetylcysteine; Animals; Astrocytes; Biomarkers; Case-Control Studies; Cell Count; Cognitive Dysfunction; Disease Models, Animal; Electric Stimulation; Epilepsy; Glutathione; Hippocampus; HMGB1 Protein; Humans; Isothiocyanates; Male; Neurons; Oxidative Stress; Rats; Status Epilepticus; Sulfoxides | 2019 |
Targeting NRF2 for the Treatment of Friedreich's Ataxia: A Comparison among Drugs.
Topics: Acetylcysteine; Biopsy; Down-Regulation; Drug Evaluation, Preclinical; Frataxin; Friedreich Ataxia; Humans; Iron-Binding Proteins; Isothiocyanates; Molecular Targeted Therapy; NF-E2-Related Factor 2; Oxidation-Reduction; Signal Transduction; Sulfoxides; Time Factors; Transcriptional Activation | 2019 |
Effects of antioxidants on oxidative stress and inflammatory responses of human bronchial epithelial cells exposed to particulate matter and cigarette smoke extract.
Topics: Acetylcysteine; Antioxidants; Bronchi; Cell Line; Cell Survival; Cytokines; Epithelial Cells; Humans; Isothiocyanates; NF-E2-Related Factor 2; Oxidative Stress; Particulate Matter; Reactive Oxygen Species; Sulfoxides; Tobacco Products | 2020 |
Treatment of dilated cardiomyopathy in a mouse model of Friedreich's ataxia using N-acetylcysteine and identification of alterations in microRNA expression that could be involved in its pathogenesis.
Topics: Acetylcysteine; Animals; Basic-Leucine Zipper Transcription Factors; Cardiomyopathy, Dilated; Cell Line, Tumor; Disease Models, Animal; Frataxin; Friedreich Ataxia; Gene Expression Regulation; Humans; Iron-Binding Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Mice, Knockout; MicroRNAs; Myocytes, Cardiac; NF-E2-Related Factor 2; Sulfoxides | 2020 |
Delineating binding potential, stability of Sulforaphane-N-acetyl-cysteine in the active site of histone deacetylase 2 and testing its cytotoxicity against distinct cancer lines through stringent molecular dynamics, DFT and cell-based assays.
Topics: Acetylcysteine; Antineoplastic Agents; Benzamides; Binding Sites; Catalytic Domain; Cell Line, Tumor; Cell Survival; Density Functional Theory; Drug Stability; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Humans; Hydrogen Bonding; Isothiocyanates; Molecular Docking Simulation; Mutagenesis; Pyridines; Sulfoxides; Thermodynamics | 2021 |
Targeting Oxidative Stress with Antioxidant Duotherapy after Experimental Traumatic Brain Injury.
Topics: Acetylcysteine; Animals; Antioxidants; Brain; Brain Injuries, Traumatic; Cell Line; Cell Survival; Cells, Cultured; Disease Models, Animal; Gene Expression; Heme Oxygenase-1; Isothiocyanates; Male; Mice, Inbred C57BL; Microglia; Neurons; NF-E2-Related Factor 2; Oxidative Stress; Rats, Sprague-Dawley; Sulfoxides | 2021 |
GSH Levels Serve As a Biological Redox Switch Regulating Sulforaphane-Induced Cell Fate in Human Lens Cells.
Topics: Acetylcysteine; Activating Transcription Factor 6; Aged; Aged, 80 and over; Anticarcinogenic Agents; Apoptosis; Biomarkers; Cell Line; Cell Survival; Chromatography, Liquid; Epithelial Cells; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Glutathione Reductase; Humans; Immunoblotting; Isothiocyanates; Lens, Crystalline; Membrane Potential, Mitochondrial; Middle Aged; Oxidation-Reduction; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Sulfoxides; Tandem Mass Spectrometry | 2021 |