sulforaphane has been researched along with 2-tert-butylhydroquinone in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.33) | 18.2507 |
| 2000's | 11 (36.67) | 29.6817 |
| 2010's | 17 (56.67) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Boumendjel, A; Day, BJ; Di Pietro, A; Franklin, CC; Gauthier, C; Genoux-Bastide, E; Kachadourian, R; Mahaffey, G; Pugazhenti, S | 1 |
| Gao, Y; Guo, QL; Guo, XK; Hu, R; Jia, JM; Jiang, JW; Jiang, ZY; Sun, HP; Sun, ZY; Tao, L; Wang, YJ; Xi, MY; Xu, LL; Xu, XL; Xue, X; Yang, X; Ye, M; You, QD; Zhang, MY; Zhang, XJ; Zhu, JF | 1 |
| Guo, XK; Jiang, ZY; Lu, MC; Sun, HP; Xi, MY; Xu, LL; Xu, XL; Yang, TT; You, QD; Zhang, XJ | 1 |
| Li, GH; Li, YR; Lou, HX; Ren, DM; Shen, T; Wang, XN; Xiang, L; Zhou, MX | 1 |
| Chen, J; Gu, X; Guan, M; Li, X; Qiu, J; Song, Q; Zhang, Y; Zhou, Q | 1 |
| Chen, XM; Cheng, XP; Hu, HX; Lou, HX; Ren, DM; Shen, T; Wang, SQ; Wang, XN; Xu, LT; Yang, WJ; Zhao, BB | 1 |
| Der, CJ; Kong, AN; Lei, W; Mandlekar, S; Weber, MJ; Wu, J; Yu, R | 1 |
| Fahl, WE; Kong, AN; Lei, W; Mandlekar, S; Tan, TH; Yu, R | 1 |
| Juurlink, BH; Wu, L | 1 |
| Jeffery, EH; Matusheski, NV | 1 |
| Chen, C; Hebbar, V; Jiang, ZQ; Kong, AN; Yang, B | 1 |
| Johnson, DA; Johnson, JA; Kraft, AD | 1 |
| Bowden, GT; Cooper, S; Rohwer, J; Sikorski, E; Zhang, Y; Zhu, M | 1 |
| Cross, JV; Hannink, M; Lo, SC; Templeton, DJ; Zhang, DD | 1 |
| Banning, A; Brigelius-Flohé, R; Deubel, S; Kluth, D; Zhou, Z | 1 |
| Ebert, B; Lampen, A; Seidel, A | 1 |
| Chen, W; Eblin, KE; Gandolfi, JA; Sun, Z; Wang, XJ; Zhang, DD | 1 |
| Chandrasekaran, K; Desai, V; Fiskum, G; Jafri, MS; Siebert, A | 1 |
| Jiang, YL; Qu, LY; Quan, K; Tang, XW; Wu, XY | 1 |
| Kensler, TW; Motohashi, H; Onodera, K; Satomi, S; Suzuki, T; Takaya, K; Yamamoto, M | 1 |
| Cho, IJ; Jin, SH; Ki, SH; Shin, BY | 1 |
| Choi, BH; Jung, KA; Kim, ST; Kwak, MK; Lee, JY; Nam, CW; Song, M | 1 |
| Lau, A; Tao, S; Wang, H; White, E; Whitman, SA; Zhang, DD; Zheng, Y | 1 |
| Fuller, S; Kersaitis, C; Münch, G; Ooi, L; Patel, M; Steele, ML | 1 |
| Omiecinski, CJ; Su, S; Yang, X | 1 |
| Aronowski, J; Edwards, NJ; Song, S; Sun, G; Ting, SM; Zhang, J; Zhao, X | 1 |
| Chen, C; Gu, S; Jiang, X; Lai, Y; Liu, Y; Zhang, Z | 1 |
| Hanmer, KL; Mavri-Damelin, D | 1 |
| Chen, Y; Tang, X; Wang, H; Wang, XJ; Zhang, J | 1 |
| Chang, E; Han, L; Hu, X; Ko, CC; Kwon, J; Lee, DJ; Nay, N; Powers, J; Tseng, H; Wong, SW; Wu, TH; Xue, P | 1 |
30 other study(ies) available for sulforaphane and 2-tert-butylhydroquinone
| Article | Year |
|---|---|
A synthetic chalcone as a potent inducer of glutathione biosynthesis.
Topics: Antioxidants; Cell Line, Tumor; Chalcones; Genes, Reporter; Glutamate-Cysteine Ligase; Glutathione; Holoenzymes; Humans; Intracellular Space; Luciferases; NF-E2 Transcription Factor, p45 Subunit; Response Elements; Structure-Activity Relationship; Transcription, Genetic | 2012 |
3-aroylmethylene-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-ones as potent Nrf2/ARE inducers in human cancer cells and AOM-DSS treated mice.
Topics: Active Transport, Cell Nucleus; Adenoma; Animals; Antineoplastic Agents; Antioxidant Response Elements; Azoxymethane; Blotting, Western; Cell Nucleus; Colorectal Neoplasms; Dextran Sulfate; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; Heme Oxygenase-1; Hep G2 Cells; Heterocyclic Compounds, 3-Ring; Humans; Interleukin-1beta; Interleukin-6; Mice; Mice, Inbred C57BL; Models, Chemical; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Neoplasms; NF-E2-Related Factor 2 | 2013 |
Discovery of potent Keap1-Nrf2 protein-protein interaction inhibitor based on molecular binding determinants analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Membrane Permeability; Computational Biology; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Discovery; Electrochemistry; Humans; Hydrogen Bonding; Interferometry; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Luciferases; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; NF-E2-Related Factor 2; Oxidative Stress; Protein Binding; Real-Time Polymerase Chain Reaction; RNA; Small Molecule Libraries; Transcription, Genetic | 2014 |
Discovery of natural flavonoids as activators of Nrf2-mediated defense system: Structure-activity relationship and inhibition of intracellular oxidative insults.
Topics: Arsenic; Biological Products; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Discovery; Epithelial Cells; Flavonoids; Humans; Molecular Structure; NF-E2-Related Factor 2; Structure-Activity Relationship | 2018 |
Synthesis and assessment of phenylacrylamide derivatives as potential anti-oxidant and anti-inflammatory agents.
Topics: Acrylamide; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Survival; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Hydrogen Peroxide; Inflammation; Molecular Structure; Oxidative Stress; Structure-Activity Relationship | 2019 |
4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of
Topics: Animals; Antioxidants; Epithelial Cells; Fruit; Humans; Kelch-Like ECH-Associated Protein 1; Lung; Mice; Molecular Structure; NF-E2-Related Factor 2; Nicotiana; Oxidative Stress; Physalis; Signal Transduction; Smoke; Withanolides | 2020 |
Role of a mitogen-activated protein kinase pathway in the induction of phase II detoxifying enzymes by chemicals.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Genes, Reporter; Humans; Hydroquinones; Isothiocyanates; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; NAD(P)H Dehydrogenase (Quinone); Recombinant Proteins; Signal Transduction; Sulfoxides; Thiocyanates; Tumor Cells, Cultured | 1999 |
p38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens.
Topics: Animals; Antioxidants; beta-Naphthoflavone; Butylated Hydroxyanisole; Carcinogens; Enzyme Activation; Enzyme Induction; Gene Expression Regulation, Enzymologic; Genes, Reporter; Humans; Hydroquinones; Imidazoles; Inactivation, Metabolic; Isothiocyanates; Kinetics; MAP Kinase Kinase 3; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; NAD(P)H Dehydrogenase (Quinone); p38 Mitogen-Activated Protein Kinases; Protein-Tyrosine Kinases; Pyridines; Sulfoxides; Thiocyanates; Tumor Cells, Cultured | 2000 |
The impaired glutathione system and its up-regulation by sulforaphane in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Animals; Cells, Cultured; Glutathione; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydroquinones; Hypertension; Isothiocyanates; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfoxides; Thiocyanates; Up-Regulation | 2001 |
Comparison of the bioactivity of two glucoraphanin hydrolysis products found in broccoli, sulforaphane and sulforaphane nitrile.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Brassica; Colon; Glucose; Glucosinolates; Glutathione Transferase; Hydrolysis; Hydroquinones; Imidoesters; Isothiocyanates; Liver; Male; NAD(P)H Dehydrogenase (Quinone); Nitriles; Oximes; Pancreas; Rats; Rats, Inbred F344; Sulfoxides; Thiocyanates | 2001 |
Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers.
Topics: Aldehyde Reductase; Animals; Anticarcinogenic Agents; beta-Naphthoflavone; Chemoprevention; Drug Screening Assays, Antitumor; Enzyme Induction; Enzyme Inhibitors; Female; Glutathione Reductase; Glutathione Transferase; Humans; Hydroquinones; Inactivation, Metabolic; Isothiocyanates; Male; Mice; NAD(P)H Dehydrogenase (Quinone); Oxidoreductases; Sulfoxides; Thiocyanates; Tumor Cells, Cultured | 2003 |
Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.
Topics: Adenoviridae; Animals; Antioxidants; Astrocytes; Calcium-Transporting ATPases; Cell Death; Cell Separation; Cells, Cultured; Cytoprotection; DNA-Binding Proteins; Enzyme Inhibitors; Glutamic Acid; Humans; Hydroquinones; Isothiocyanates; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidants; Oxidative Stress; Phosphoinositide-3 Kinase Inhibitors; Response Elements; Sulfoxides; Thiocyanates; Trans-Activators | 2004 |
Phase II enzyme inducer, sulforaphane, inhibits UVB-induced AP-1 activation in human keratinocytes by a novel mechanism.
Topics: Anticarcinogenic Agents; Binding Sites; Calcium-Transporting ATPases; Cells, Cultured; Collagenases; Electrophoretic Mobility Shift Assay; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Glutathione; Humans; Hydroquinones; Isothiocyanates; Keratinocytes; Luciferases; NAD(P)H Dehydrogenase (Quinone); Promoter Regions, Genetic; Sulfoxides; Thiocyanates; Transcription Factor AP-1; Transfection; Ultraviolet Rays | 2004 |
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Amino Acid Substitution; Animals; Anticarcinogenic Agents; Antioxidants; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Cullin Proteins; DNA-Binding Proteins; Genes, Reporter; Humans; Hydroquinones; Immunoblotting; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Luciferases; Lysine; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Precipitin Tests; Protein Structure, Tertiary; Proteins; Serine; Substrate Specificity; Sulfoxides; Thiocyanates; Trans-Activators; Ubiquitin-Protein Ligases; Ubiquitins | 2004 |
The GI-GPx gene is a target for Nrf2.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Cell Line, Tumor; Curcumin; DNA-Binding Proteins; Gene Expression Regulation; Genes, Reporter; Glutathione Peroxidase; Humans; Hydroquinones; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Promoter Regions, Genetic; Protein Binding; Proteins; Response Elements; Sulfoxides; Thiocyanates; Trans-Activators | 2005 |
Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzo(a)pyrene; Biological Transport; Caco-2 Cells; Catechin; Cell Line, Tumor; Chalcones; Flavonoids; Gene Expression; Humans; Hydroquinones; Indoles; Isothiocyanates; Maleates; Molecular Structure; Neoplasm Proteins; Plant Extracts; Quercetin; Receptors, Aryl Hydrocarbon; Resveratrol; RNA, Messenger; Silymarin; Stilbenes; Sulfoxides; Thiocyanates; Transfection | 2007 |
Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Arsenicals; Arsenites; Cell Line; Embryo, Mammalian; Environmental Pollutants; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Humans; Hydroquinones; Isothiocyanates; Mice; NF-E2-Related Factor 2; RNA, Small Interfering; Sodium Compounds; Sulfoxides; Thiocyanates; Urinary Bladder; Urothelium | 2007 |
Nrf2 activators provide neuroprotection against 6-hydroxydopamine toxicity in rat organotypic nigrostriatal cocultures.
Topics: Animals; Antioxidants; Cell Death; Coculture Techniques; Corpus Striatum; Cytoprotection; Dopamine; Gene Expression; Hydroquinones; Isothiocyanates; NAD(P)H Dehydrogenase (Quinone); Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sulfoxides; Thiocyanates | 2009 |
[Effect of tBHQ and sulforaphane on Nrf2-ARE signaling pathway of Caco2 cells].
Topics: Anticarcinogenic Agents; Antioxidants; Caco-2 Cells; Calcium-Transporting ATPases; Humans; Hydroquinones; Isothiocyanates; NF-E2-Related Factor 2; Oxidative Stress; Response Elements; Signal Transduction; Sulfoxides; Thiocyanates | 2010 |
Validation of the multiple sensor mechanism of the Keap1-Nrf2 system.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Animals; Antioxidants; Azoles; Cytoskeletal Proteins; Dimethyl Fumarate; Fumarates; Gene Expression; Gene Expression Regulation; Glutamate-Cysteine Ligase; HEK293 Cells; Humans; Hydroquinones; Imidazoles; Isoindoles; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Macrophages, Peritoneal; Maleates; Mice; Mice, Transgenic; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oleanolic Acid; Organoselenium Compounds; Oxidants; Oxidative Stress; Sulfoxides; Transcriptional Activation | 2012 |
Nrf2-ARE pathway regulates induction of Sestrin-2 expression.
Topics: Animals; Antioxidant Response Elements; Antioxidants; Cell Line; Gene Expression; Gene Expression Regulation; Heat-Shock Proteins; Hepatocytes; Humans; Hydrogen Peroxide; Hydroquinones; Isothiocyanates; Liver; Mice; NF-E2-Related Factor 2; Nuclear Proteins; Oxidants; Sequence Analysis, DNA; Sulfoxides; Thiocyanates; Transcriptional Activation | 2012 |
Identification of aldo-keto reductases as NRF2-target marker genes in human cells.
Topics: 20-Hydroxysteroid Dehydrogenases; Acrolein; Aldehyde Reductase; Biomarkers; Enzyme Induction; Gene Expression Regulation; Gene Knockdown Techniques; Gene Silencing; Genetic Markers; Humans; Hydrogen Peroxide; Hydroquinones; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Kidney Tubules, Proximal; Leukemia, Monocytic, Acute; Monocytes; NF-E2-Related Factor 2; Oxidative Stress; Sulfoxides; Thiocyanates; U937 Cells | 2013 |
Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Arsenic; Autophagy; Cell Line; Cell Survival; Cytoskeletal Proteins; Enzyme Activation; Epithelium; HEK293 Cells; Humans; Hydroquinones; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Lung; Mice; Microtubule-Associated Proteins; Neoplasms; NF-E2-Related Factor 2; RNA Interference; RNA, Small Interfering; Signal Transduction; Sulfoxides; Thiocyanates; Transcription Factor TFIIH; Transcription Factors | 2013 |
Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells.
Topics: Astrocytes; Cell Line, Tumor; Cell Survival; Dipeptides; Glutathione; Homocysteine; Humans; Hydroquinones; Isothiocyanates; NF-E2-Related Factor 2; Plant Extracts; Resveratrol; Stilbenes; Sulfoxides; Thioctic Acid | 2013 |
Intronic DNA elements regulate Nrf2 chemical responsiveness of the human microsomal epoxide hydrolase gene (EPHX1) through a far upstream alternative promoter.
Topics: Anticarcinogenic Agents; Antioxidants; Blotting, Western; Bronchi; Cells, Cultured; Chromatin Immunoprecipitation; Electrophoretic Mobility Shift Assay; Epoxide Hydrolases; Gene Expression Regulation; Humans; Hydroquinones; Introns; Isothiocyanates; Lung Neoplasms; NF-E2-Related Factor 2; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Sulfoxides; Transcription, Genetic | 2014 |
Cleaning up after ICH: the role of Nrf2 in modulating microglia function and hematoma clearance.
Topics: Animals; Brain; CD36 Antigens; Cell Count; Cells, Cultured; Cerebral Hemorrhage; Hydrogen Peroxide; Hydroquinones; Isothiocyanates; Mice; Mice, Knockout; Microglia; NF-E2 Transcription Factor, p45 Subunit; Phagocytosis; Sulfoxides | 2015 |
Protection of Nrf2 against arsenite-induced oxidative damage is regulated by the cyclic guanosine monophosphate-protein kinase G signaling pathway.
Topics: Antioxidants; Arsenites; Cell Line; Cyclic GMP-Dependent Protein Kinases; Humans; Hydroquinones; Isothiocyanates; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction; Sulfoxides | 2017 |
Peroxidasin is a novel target of the redox-sensitive transcription factor Nrf2.
Topics: Extracellular Matrix Proteins; HEK293 Cells; HeLa Cells; Humans; Hydrogen Peroxide; Hydroquinones; Isothiocyanates; NF-E2-Related Factor 2; Oxidation-Reduction; Peroxidase; Peroxidasin; Promoter Regions, Genetic; Sulfoxides; Transcriptional Activation | 2018 |
Using Nrf2/antioxidant response element-dependent signaling to assess the toxicity potential of fly ash particles.
Topics: Antioxidant Response Elements; Cell Survival; China; Coal Ash; DNA Damage; Dose-Response Relationship, Drug; Humans; Hydroquinones; Incineration; Isothiocyanates; MCF-7 Cells; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Particulate Matter; Signal Transduction; Sulfoxides | 2019 |
CDDO-Me, Sulforaphane and tBHQ attenuate the RANKL-induced osteoclast differentiation via activating the NRF2-mediated antioxidant response.
Topics: Animals; Antioxidants; Cell Differentiation; Cell Line; Cells, Cultured; Hydroquinones; Isothiocyanates; Male; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oleanolic Acid; Osteoclasts; Osteogenesis; RANK Ligand; Reactive Oxygen Species; Sulfoxides | 2019 |