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sulfobromophthalein and methotrexate

sulfobromophthalein has been researched along with methotrexate in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199018 (62.07)18.7374
1990's9 (31.03)18.2507
2000's0 (0.00)29.6817
2010's2 (6.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ekins, S; Williams, AJ; Xu, JJ1
Henderson, GB1
Henderson, GB; Strauss, BP1
O'Leary, DF; Sirotnak, FM1
Henderson, GB; Tsuji, JM3
Henderson, GB; Zevely, EM1
Henderson, GB; Kumar, HP; Tsuji, JM1
Hollander, D; Said, HM1
Lee, JC; Maibach, HI; Shapiro, HA; Trowbridge, JO1
Aach, RD; Eisen, AZ; Grisham, JW; Reese, LT1
Almeyda, J; Baker, H; Barnardo, D; Landells, J; Levene, G1
Dabels, J; Diwok, K; Leithäuser, W; Moldenhauer, E; Nowotny, P1
Leonardi, D; Megirian, R1
Dubin, HV; Harrell, ER1
Cox, JW; Frost, P; Kalser, M; Millard, MM; Suringa, DW; Weinstein, GD1
Dahl, MG; Gregory, MM; Scheuer, PJ1
Borrie, PF; Mackay, IB; Robinson, TW1
Bertino, JR; Coward, JK; Hsieh, P; McGuire, JJ1
Gewirtz, DA; Goldman, ID; Randolph, JK1
Brigle, KE; Goldman, ID; Sierra, EE; Spinella, MJ3
Henderson, GB; Hughes, TR1
Honscha, W; Petzinger, E1
NORCROSS, JW; SULLIVAN, RD; WATKINS, E1
Hong, M; Huang, J; Liu, X; Sun, Y; Zhan, K; Zhang, Z1

Other Studies

29 other study(ies) available for sulfobromophthalein and methotrexate

ArticleYear
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Separation and inhibitor specificity of a second unidirectional efflux route for methotrexate in L1210 cells.
    Biochimica et biophysica acta, 1992, Oct-05, Volume: 1110, Issue:2

    Topics: Adenosine Triphosphate; Animals; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Leukemia L1210; Methotrexate; Mice; Probenecid; Prostaglandins A; Quinidine; Reserpine; Sulfobromophthalein; Tumor Cells, Cultured; Verapamil; Vincristine

1992
Evidence for cAMP and cholate extrusion in C6 rat glioma cells by a common anion efflux pump.
    The Journal of biological chemistry, 1991, Jan-25, Volume: 266, Issue:3

    Topics: Animals; Antimycin A; Biological Transport, Active; Cholic Acids; Cyclic AMP; Glioma; Isoproterenol; Methotrexate; Probenecid; Prostaglandins A; Rats; Sulfobromophthalein; Tumor Cells, Cultured; Verapamil

1991
The issues of transport multiplicity and energetics pertaining to methotrexate efflux in L1210 cells addressed by an analysis of cis and trans effects of inhibitors.
    Cancer research, 1991, Mar-01, Volume: 51, Issue:5

    Topics: Adenosine Triphosphate; Animals; Biological Transport; Energy Metabolism; Leukemia L1210; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Probenecid; Sulfobromophthalein; Verapamil

1991
Identification of cholate as a shared substrate for the unidirectional efflux systems for methotrexate in L1210 mouse cells.
    Biochimica et biophysica acta, 1990, Jan-23, Volume: 1051, Issue:1

    Topics: Animals; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cholic Acids; Cytochalasin B; Folic Acid; Glucose; Leukemia L1210; Methotrexate; Mice; Probenecid; Substrate Specificity; Sulfobromophthalein; Temperature; Tumor Cells, Cultured; Uric Acid; Vincristine

1990
Methotrexate efflux in L1210 cells. Kinetic and specificity properties of the efflux system sensitive to bromosulfophthalein and its possible identity with a system which mediates the efflux of 3',5'-cyclic AMP.
    The Journal of biological chemistry, 1987, Oct-05, Volume: 262, Issue:28

    Topics: Adenosine Triphosphate; Animals; Biological Transport; Buffers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cyclic AMP; Glucose; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Leukemia L1210; Methotrexate; Mice; Onium Compounds; Organophosphorus Compounds; Potassium; Sulfobromophthalein

1987
Identification of the bromosulfophthalein-sensitive efflux route for methotrexate as the site of action of vincristine in the vincristine-dependent enhancement of methotrexate uptake in L1210 cells.
    Cancer research, 1988, Nov-01, Volume: 48, Issue:21

    Topics: Adenosine Triphosphate; Animals; Cyclic AMP; Cytoskeleton; Energy Metabolism; Leukemia L1210; Methotrexate; Onium Compounds; Organophosphorus Compounds; Sulfobromophthalein; Tumor Cells, Cultured; Vincristine

1988
Characterization of the multiple transport routes for methotrexate in L1210 cells using phthalate as a model anion substrate.
    The Journal of membrane biology, 1985, Volume: 85, Issue:3

    Topics: Animals; Biological Transport; Carbon Radioisotopes; Glucose; Kinetics; Leukemia L1210; Methotrexate; Mice; Oligomycins; Phosphates; Phthalic Acids; Radioisotope Dilution Technique; Sulfobromophthalein; Thiamine Pyrophosphate

1985
Characterization of the individual transport routes that mediate the influx and efflux of methotrexate in CCRF-CEM human lymphoblastic cells.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Cells, Cultured; Glucose; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Leukemia; Leukemia L1210; Lymphocytes; Methotrexate; Mice; Neoplasm Proteins; Oligomycins; Probenecid; Sulfobromophthalein; Tetrahydrofolates; Tritium

1986
Inhibitory effect of bile salts on the enterohepatic circulation of methotrexate in the unanesthetized rat: inhibition of methotrexate intestinal absorption.
    Cancer chemotherapy and pharmacology, 1986, Volume: 16, Issue:2

    Topics: Animals; Bile; Bile Acids and Salts; Drug Interactions; Enterohepatic Circulation; Folic Acid; Hydrogen-Ion Concentration; Intestinal Absorption; Liver; Male; Methotrexate; Perfusion; Rats; Rats, Inbred Strains; Rose Bengal; Sulfobromophthalein; Tetrahydrofolates

1986
Liver disease in psoriatics--An effect of methotrexate therapy?
    Archives of dermatology, 1974, Volume: 110, Issue:4

    Topics: Adolescent; Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Biopsy; Cell Nucleus; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Humans; Infant; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Methods; Methotrexate; Mitochondria, Liver; Psoriasis; Sulfobromophthalein; Time Factors

1974
Psoriasis-liver-methotrexate interactions.
    Archives of dermatology, 1973, Volume: 108, Issue:1

    Topics: Administration, Oral; Adrenal Cortex Hormones; Age Factors; Alanine Transaminase; Alcohol Drinking; Alkaline Phosphatase; Aspartate Aminotransferases; Biopsy; Diabetes Complications; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Obesity; Psoriasis; Sex Factors; Sulfobromophthalein; Time Factors

1973
Effects of methotrexate on the liver in psoriasis.
    The Journal of investigative dermatology, 1974, Volume: 62, Issue:6

    Topics: Biopsy; Cell Nucleus; Chemical and Drug Induced Liver Injury; Ethanol; Fatty Liver; Follow-Up Studies; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Necrosis; Psoriasis; Sulfobromophthalein

1974
Hepatic structure and function in psoriasis before and after treatment with methotrexate.
    Gut, 1971, Volume: 12, Issue:10

    Topics: Biopsy; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Prospective Studies; Psoriasis; Sulfobromophthalein

1971
[Liver changes in psoriasis vulgaris].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1971, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Alanine Transaminase; Aspartate Aminotransferases; Fatty Liver; Female; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Sulfobromophthalein

1971
Effect of chlorambucil and methotrexate on the removal of bromsulfalein from blood after India ink.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 168, Issue:1

    Topics: Animals; Blood Flow Velocity; Chlorambucil; Drug Antagonism; Drug Synergism; Ink; Leucovorin; Liver; Male; Methotrexate; Mononuclear Phagocyte System; Rats; Sulfobromophthalein

1967
Liver disease associated with methotrexate treatment of psoriatic patients.
    Archives of dermatology, 1970, Volume: 102, Issue:5

    Topics: Adult; Alanine Transaminase; Aminopterin; Arthritis; Aspartate Aminotransferases; Blood Cell Count; Cell Division; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; DNA Replication; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Sulfobromophthalein; Tetrahydrofolate Dehydrogenase

1970
Evaluation of possible chronic hepatotoxicity from methotrexate for psoriasis.
    Archives of dermatology, 1970, Volume: 102, Issue:6

    Topics: Adult; Aged; Alcohol Drinking; Biopsy; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis; Sulfobromophthalein

1970
Liver damage due to methotrexate in patients with psoriasis.
    British medical journal, 1971, Mar-20, Volume: 1, Issue:5750

    Topics: Adult; Aged; Biopsy; Cell Nucleus; Fatty Liver; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Middle Aged; Psoriasis; Sulfobromophthalein

1971
The treatment of psoriasis with methotrexate.
    The British journal of dermatology, 1967, Volume: 79, Issue:2

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Alopecia; Anemia, Macrocytic; Aspartate Aminotransferases; Diarrhea; Dyspepsia; Female; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Nucleotidases; Psoriasis; Stomatitis; Sulfobromophthalein

1967
In vitro methotrexate polyglutamate synthesis by rat liver folylpolyglutamate synthetase and inhibition by bromosulfophthalein.
    Advances in experimental medicine and biology, 1983, Volume: 163

    Topics: Animals; Chromatography, High Pressure Liquid; Corynebacterium; Escherichia coli; Kinetics; Liver; Methotrexate; Mice; Neurospora crassa; Peptide Synthases; Peptides; Polyglutamic Acid; Rabbits; Rats; Species Specificity; Sulfobromophthalein

1983
Potent bile salt and organic anion inhibition of methotrexate uptake and accumulation in the freshly isolated rat hepatocyte.
    Cancer research, 1980, Volume: 40, Issue:6

    Topics: Adenine Nucleotides; Animals; Anions; Bile Acids and Salts; Biological Transport; Cells, Cultured; Depression, Chemical; Kinetics; Liver; Male; Methotrexate; Rats; Rose Bengal; Sulfobromophthalein

1980
Comparison of transport properties of the reduced folate carrier and folate receptor in murine L1210 leukemia cells.
    Biochemical pharmacology, 1995, Oct-12, Volume: 50, Issue:8

    Topics: Animals; Biological Transport; Carrier Proteins; Folate Receptors, GPI-Anchored; Hydrogen-Ion Concentration; Kinetics; Leukemia L1210; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Mice; Probenecid; Receptors, Cell Surface; Reduced Folate Carrier Protein; Sulfobromophthalein; Tumor Cells, Cultured

1995
Distinguishing between folate receptor-alpha-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells.
    The Journal of biological chemistry, 1995, Apr-07, Volume: 270, Issue:14

    Topics: Alkenes; Animals; Biological Transport; Carrier Proteins; Energy Metabolism; Folate Receptors, GPI-Anchored; Folic Acid; Hydrogen-Ion Concentration; Ions; Leukemia L1210; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Mice; Polyenes; Probenecid; Pyrones; Receptors, Cell Surface; Reduced Folate Carrier Protein; Sulfobromophthalein; Temperature; Transfection; Tumor Cells, Cultured

1995
Altered expression of unidirectional extrusion routes for methotrexate and cholate in an efflux variant of L1210 cells.
    Biochimica et biophysica acta, 1993, Oct-10, Volume: 1152, Issue:1

    Topics: Animals; Cell Division; Cholic Acids; Drug Interactions; Drug Tolerance; Exocytosis; Leukemia L1210; Methotrexate; Mice; Probenecid; Sulfobromophthalein; Tumor Cells, Cultured

1993
pH dependence of methotrexate transport by the reduced folate carrier and the folate receptor in L1210 leukemia cells. Further evidence for a third route mediated at low pH.
    Biochemical pharmacology, 1997, Jan-24, Volume: 53, Issue:2

    Topics: Animals; Biological Transport; Carrier Proteins; Cell Division; Folate Receptors, GPI-Anchored; Folic Acid Antagonists; Hydrogen-Ion Concentration; Leukemia L1210; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Mice; Receptors, Cell Surface; Reduced Folate Carrier Protein; Sulfobromophthalein; Tumor Cells, Cultured

1997
Characterization of the bile acid sensitive methotrexate carrier of rat liver cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:5

    Topics: Animals; Bile Acids and Salts; Buffers; Carrier Proteins; Cell Line; Cell Membrane; Cells, Cultured; Folate Receptors, GPI-Anchored; Folic Acid; Kinetics; Liver; Male; Methotrexate; Oligomycins; Rats; Rats, Wistar; Receptors, Cell Surface; Sodium Chloride; Sulfobromophthalein; Tetrahydrofolates; Tritium; Xenobiotics

1999
CHEMOTHERAPY OF METASTATIC LIVER CANCER BY PROLONGED HEPATIC-ARTERY INFUSION.
    The New England journal of medicine, 1964, Feb-13, Volume: 270

    Topics: Alkaline Phosphatase; Bile Duct Neoplasms; Bilirubin; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Erythrocyte Count; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Sulfobromophthalein; Transaminases; Uterine Cervical Neoplasms

1964
Identification of multiple binding sites for substrate transport in bovine organic anion transporting polypeptide 1a2.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:3

    Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Cattle; Estrone; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Methotrexate; Organic Anion Transporters; Protein Structure, Secondary; Recombinant Proteins; Rifampin; Sulfobromophthalein; Taurocholic Acid; Transfection

2013