Compounds > sulfasalazine

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sulfasalazine and adenosine

sulfasalazine has been researched along with adenosine in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (30.00)	18.2507
2000's	2 (20.00)	29.6817
2010's	5 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Cronstein, BN	1
Buckley, MT; Carlin, G; Cronstein, BN; Gadangi, P; Levin, RI; Longaker, M; Montesinos, MC; Naime, D; Recht, PA	1
Balter, L; Carlin, G; Cronstein, BN; Huie, MA; Montesinos, MC; Morabito, L; Resta, R; Schreibman, DM; Thompson, LF	1
Ganga, A; Rodenburg, RJ; van de Putte, LB; van Lent, PL; van Venrooij, WJ	1
Hashimoto, T; Konno, Y; Matsuda, Y; Nagai, M; Satsukawa, M; Taguchi, T; Yamashita, S	1

Reviews

2 review(s) available for sulfasalazine and adenosine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
A novel approach to the development of anti-inflammatory agents: adenosine release at inflamed sites. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 1995, Volume: 43, Issue:1 Topics: Adenosine; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Humans; Inflammation; Methotrexate; Sulfasalazine	1995

Other Studies

8 other study(ies) available for sulfasalazine and adenosine

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
The anti-inflammatory mechanism of sulfasalazine is related to adenosine release at inflamed sites. Journal of immunology (Baltimore, Md. : 1950), 1996, Mar-01, Volume: 156, Issue:5 Topics: Acyltransferases; Adenosine; Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Endothelium, Vascular; Female; Humans; Hydroxymethyl and Formyl Transferases; Mice; Mice, Inbred BALB C; Neutrophil Activation; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Ribonucleotides; Sulfasalazine	1996
Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5'-nucleotidase-mediated conversion of adenine nucleotides. The Journal of clinical investigation, 1998, Jan-15, Volume: 101, Issue:2 Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Animals; Anti-Inflammatory Agents; Humans; Methotrexate; Mice; Mice, Inbred BALB C; Sulfasalazine; Tumor Cells, Cultured	1998
The antiinflammatory drug sulfasalazine inhibits tumor necrosis factor alpha expression in macrophages by inducing apoptosis. Arthritis and rheumatism, 2000, Volume: 43, Issue:9 Topics: Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase Inhibitors; Cells, Cultured; Cysteine Proteinase Inhibitors; Humans; Macrophage Activation; Macrophages; Macrophages, Peritoneal; Methotrexate; Mice; Mice, Inbred C57BL; Sulfasalazine; Tumor Necrosis Factor-alpha	2000
In vivo assessment of the impact of efflux transporter on oral drug absorption using portal vein-cannulated rats. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:8 Topics: Absorption; Adenosine; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Catheterization; Dibenzocycloheptenes; Diketopiperazines; Heterocyclic Compounds, 4 or More Rings; Male; Portal Vein; Quinolines; Rats; Rats, Sprague-Dawley; Sulfasalazine; Terfenadine; Topotecan	2013