sulfaphenazole has been researched along with warfarin in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (14.29) | 18.7374 |
| 1990's | 11 (39.29) | 18.2507 |
| 2000's | 8 (28.57) | 29.6817 |
| 2010's | 5 (17.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Afzelius, L; Andersson, TB; Baroni, M; Cruciani, G; Karlén, A; Masimirembwa, CM; Mecucci, S; Zamora, I | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, CH; De Clercq, E; Feng, D; Ginex, T; Kang, D; Lee, KH; Liu, X; Luque, FJ; Murugan, NA; Pannecouque, C; Steitz, TA; Wang, Z; Wei, F; Wu, G; Yang, Y; Zhan, P; Zhang, H; Zhang, J; Zhao, T | 1 |
| Adebesin, AM; Falck, JR; Fischer, R; Konkel, A; Lossie, J; Paudyal, MP; Puli, N; Schunck, WH; Vijaykumar, J; Wesser, T; Westphal, C; Zhu, C | 1 |
| Brown, KF; Crooks, MJ | 1 |
| Eckhardt, W; Rudolph, R; Sauer, H; Schubert, WR; Undeutsch, D | 1 |
| Krieglstein, J | 1 |
| Schrogie, JJ; Solomon, HM | 1 |
| Binkley, SN; Ring, BJ; VandenBranden, M; Wrighton, SA | 1 |
| Gonzalez, FJ; Korzekwa, KR; Marra, C; Tracy, TS; Wrighton, SA | 1 |
| Jones, BC; Smith, DA; Tyman, CA | 1 |
| Shimada, T; Yamazaki, H | 1 |
| Inoue, K; Kamataki, T; Kodama, T; Nagashima, K; Nakamura, K; Shimada, N; Shimizu, T; Yokoi, T | 1 |
| Inoue, T; Kuroiwa, Y; Nakajima, M; Shimada, N; Tokudome, S; Yamamoto, T | 1 |
| Inoue, K; Shimada, T; Yamazaki, H | 1 |
| Griffin, KJ; Johnson, EF; Jung, F; Richardson, TH; Song, W; Yang, M | 1 |
| Fisher, MB; Haining, RL; Henne, KR; Jones, JP; Koop, DR; Rettie, AE; Trager, WF | 1 |
| Gorski, JC; Hall, SD; Hamman, MA; Jones, DR; Wrighton, SA | 1 |
| He, M; Jones, JP; Korzekwa, KR; Rettie, AE; Trager, WF | 1 |
| Aoyama, R; Jones, JP; Rao, S; Rettie, A; Schrag, M; Trager, WF | 1 |
| Beckurts, KT; Brachtendorf, L; Fuhr, U; Hölscher, AH; Jetter, A | 1 |
| Fouda, HG; Khojasteh-Bakht, SC; Prakash, C; Rossulek, MI | 1 |
| Gottesdiener, KM; Kari, PP; Marbury, T; Miller, JL; Mistry, GC; Rodrigues, AD; Simpson, RC; Wagner, JA; Winchell, GA | 1 |
| Horie, T; Inoue, T; Kitamura, S; Nitta, K; Ohta, S; Sugihara, K | 1 |
| Hu, X; Wang, P; Zhang, L; Zhang, LF | 1 |
1 review(s) available for sulfaphenazole and warfarin
| Article | Year |
|---|---|
[Plasma protein binding of drugs].
Topics: Adult; Age Factors; Bilirubin; Blood Protein Disorders; Chemical Phenomena; Chemistry; Chromatography, Gel; Coumarins; Glucocorticoids; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Kidney; Kidney Diseases; Methotrexate; Pharmaceutical Preparations; Protein Binding; Serum Albumin; Sulfaphenazole; Ultracentrifugation; Water | 1969 |
1 trial(s) available for sulfaphenazole and warfarin
| Article | Year |
|---|---|
The effect of ketoconazole on the pharmacokinetics of a selective alpha 1A-adrenoceptor antagonist.
Topics: Administration, Oral; Adrenergic alpha-1 Receptor Antagonists; Adult; Area Under Curve; Carbon Radioisotopes; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Fomepizole; Half-Life; Humans; Ketoconazole; Male; Microsomes, Liver; Pyrazoles; Pyrimidinones; Quinidine; Receptors, Adrenergic, alpha-1; Sulfaphenazole; Theophylline | 2005 |
26 other study(ies) available for sulfaphenazole and warfarin
| Article | Year |
|---|---|
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Conformer- and alignment-independent model for predicting structurally diverse competitive CYP2C9 inhibitors.
Topics: Amino Acids; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 CYP2C9; Enzyme Inhibitors; Models, Molecular; Molecular Conformation; Molecular Structure; Quantitative Structure-Activity Relationship | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Identification of Dihydrofuro[3,4- d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties.
Topics: Animals; Anti-HIV Agents; Binding Sites; Cell Line, Tumor; Furans; HIV Reverse Transcriptase; HIV-1; Humans; Male; Microbial Sensitivity Tests; Molecular Dynamics Simulation; Molecular Structure; Pyrimidines; Rats, Wistar; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2019 |
Development of Robust 17(
Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Arachidonic Acids; Dose-Response Relationship, Drug; Drug Stability; Epoxide Hydrolases; Esterification; Hepatocytes; Humans; Male; Mice; Microsomes, Liver; Myocardial Infarction; Myocytes, Cardiac; Rats, Sprague-Dawley; Rats, Wistar | 2019 |
Displacement of tolbutamide, glibencalmide and chlorpropamide from serum albumin by anionic drugs.
Topics: Acetaminophen; Animals; Cattle; Chlorpropamide; Dialysis; Glyburide; Humans; Phenylbutazone; Protein Binding; Salicylates; Serum Albumin; Serum Albumin, Bovine; Sulfaphenazole; Tolbutamide; Warfarin | 1976 |
[Pharmacological interference of glibornuride with sulfaphenazole, phenylbutazone, and phenprocoumon in man].
Topics: Adult; Benzyl Compounds; Blood Glucose; Camphanes; Coumarins; Diabetes Mellitus; Drug Interactions; Half-Life; Humans; Hypoglycemic Agents; Kinetics; Male; Middle Aged; Phenylbutazone; Sulfaphenazole; Sulfonylurea Compounds; Sulfur Isotopes | 1972 |
The effect of various drugs on the binding of warfarin-14C to human albumin.
Topics: Atropine; Butyrates; Carbon Isotopes; Phenethylamines; Phenylbutazone; Protein Binding; Serum Albumin; Sulfaphenazole; Thyroxine; Warfarin | 1967 |
Interaction of human liver cytochromes P450 in vitro with LY307640, a gastric proton pump inhibitor.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Coumarins; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Kinetics; Liver; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; Omeprazole; Proton-Translocating ATPases; Rabbits; Rabeprazole; Recombinant Proteins; Sulfaphenazole; Theophylline | 1996 |
Involvement of multiple cytochrome P450 isoforms in naproxen O-demethylation.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dealkylation; Humans; In Vitro Techniques; Microsomes, Liver; Naproxen; Piroxicam; Sulfaphenazole; Tolbutamide; Transfection; Vaccinia virus; Warfarin | 1997 |
Identification of the cytochrome P450 isoforms involved in the O-demethylation of 4-nitroanisole in human liver microsomes.
Topics: Adult; Aged; Anisoles; Anti-Infective Agents; Anticoagulants; Antifungal Agents; Antimalarials; Binding, Competitive; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Isoenzymes; Ketoconazole; Kinetics; Male; Methylation; Microsomes, Liver; Middle Aged; Quinidine; Substrate Specificity; Sulfaphenazole; Theophylline | 1997 |
Human liver cytochrome P450 enzymes involved in the 7-hydroxylation of R- and S-warfarin enantiomers.
Topics: Animals; Anticoagulants; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Stereoisomerism; Sulfaphenazole; Tolbutamide; Warfarin | 1997 |
Oxidation of histamine H1 antagonist mequitazine is catalyzed by cytochrome P450 2D6 in human liver microsomes.
Topics: 1-Propanol; Caffeine; Chlorzoxazone; Coumarins; Cyclosporine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Histamine H1 Antagonists; Humans; Microsomes, Liver; Mixed Function Oxygenases; Phenacetin; Phenothiazines; Precipitin Tests; Sulfaphenazole; Tolbutamide | 1998 |
Cytochrome P450 2C9 catalyzes indomethacin O-demethylation in human liver microsomes.
Topics: Alkylation; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indomethacin; Isoenzymes; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Molecular Structure; Oxidoreductases, O-Demethylating; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sulfaphenazole; Tolbutamide; Tumor Cells, Cultured; Warfarin | 1998 |
Roles of two allelic variants (Arg144Cys and Ile359Leu) of cytochrome P4502C9 in the oxidation of tolbutamide and warfarin by human liver microsomes.
Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Genotype; Humans; Hydroxylation; Japan; Kinetics; Microsomes, Liver; Polymorphism, Genetic; Recombinant Proteins; Stereoisomerism; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sulfaphenazole; Tolbutamide; Warfarin | 1998 |
Identification of amino acid substitutions that confer a high affinity for sulfaphenazole binding and a high catalytic efficiency for warfarin metabolism to P450 2C19.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Catalysis; Cell Membrane; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Escherichia coli; Genetic Vectors; Humans; Mixed Function Oxygenases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Fusion Proteins; Stereoisomerism; Sulfaphenazole; Warfarin | 1998 |
Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding.
Topics: Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Binding Sites; Blotting, Western; Catalysis; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Kinetics; Lauric Acids; Leucine; Mutagenesis, Site-Directed; Phenylalanine; Protein Structure, Secondary; Static Electricity; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Sulfaphenazole; Warfarin | 1999 |
Biotransformation of alprazolam by members of the human cytochrome P4503A subfamily.
Topics: Alprazolam; Aryl Hydrocarbon Hydroxylases; B-Lymphocytes; Benzoflavones; Biotransformation; Coumarins; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; Hypnotics and Sedatives; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Quinidine; Recombinant Proteins; Sulfaphenazole; Troleandomycin | 1999 |
Structural forms of phenprocoumon and warfarin that are metabolized at the active site of CYP2C9.
Topics: 4-Hydroxycoumarins; Anticoagulants; Aryl Hydrocarbon Hydroxylases; Catalytic Domain; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Models, Molecular; Phenprocoumon; Recombinant Proteins; Stereoisomerism; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Sulfaphenazole; Warfarin | 1999 |
A refined 3-dimensional QSAR of cytochrome P450 2C9: computational predictions of drug interactions.
Topics: Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Ligands; Models, Biological; Models, Molecular; Protein Binding; Reproducibility of Results; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Sulfaphenazole; Sulfonamides; Warfarin | 2000 |
Cytochrome P450 enzymes contributing to demethylation of maprotiline in man.
Topics: Cells, Cultured; Chlorzoxazone; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzymes; Humans; Ketoconazole; Kinetics; Maprotiline; Mephenytoin; Microsomes, Liver; Models, Biological; Quinidine; Sulfaphenazole; Theophylline | 2002 |
Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543.
Topics: Adolescent; Adult; Aged; Chromans; Coumarins; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Ketoconazole; Kinetics; Male; Mephenytoin; Microsomes, Liver; Middle Aged; NADP; Oxidation-Reduction; Quinidine; Receptors, Leukotriene B4; Recombinant Proteins; Sulfaphenazole; Theophylline | 2003 |
CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver.
Topics: Adolescent; Animals; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Child; Child, Preschool; Cytochrome P-450 CYP2C9; Hepatocytes; Humans; Liver; Male; Mice; Mice, SCID; Microsomes, Liver; Sulfaphenazole; Transplantation Chimera; Warfarin | 2008 |
[Metabolism of osthol in isolated hepatocytes of rat].
Topics: Animals; Cells, Cultured; Cnidium; Coumarins; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Hepatocytes; Male; Plants, Medicinal; Quercetin; Rats; Rats, Sprague-Dawley; Rifampin; Sulfaphenazole; Troleandomycin; Yohimbine | 2009 |