sulfaphenazole has been researched along with tolbutamide in 40 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (27.50) | 18.7374 |
1990's | 16 (40.00) | 18.2507 |
2000's | 7 (17.50) | 29.6817 |
2010's | 6 (15.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Aoyama, R; Jones, JP; Rao, S; Rettie, A; Schrag, M; Trager, WF | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Ekins, S; Harwood, HJ; Hoover, DJ; Lawton, MP; Mankowski, DC; Treadway, JL | 1 |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Dai, R; Liu, Y; She, M; Wu, Z | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Brown, KF; Crooks, MJ | 1 |
Konishi, R; Shibasaki, J; Yamasaki, K | 1 |
Birkett, DJ; Pond, SM; Wade, DN | 1 |
Birkett, DJ; Doecke, CJ; Mackenzie, PI; McManus, ME; Miners, JO; Veronese, ME | 1 |
Birkett, DJ; Doecke, CJ; McManus, ME; Miners, JO; Pond, SM; Sansom, LN; Veronese, ME | 1 |
Birkett, DJ; Gregov, D; Miners, JO; Randles, D; Veronese, ME | 1 |
Brian, WR; Guengerich, FP; Lloyd, RS; Srivastava, PK; Umbenhauer, DR | 1 |
Back, DJ; Mönig, H; Ohnhaus, EE; Park, BK; Tjia, J | 1 |
Göres, E; Kiesewetter, R | 1 |
Christensen, LK; Kristensen, M | 1 |
Hellman, B | 1 |
Hanano, M; Iga, T; Sawada, Y; Sugita, O; Sugiyama, Y | 2 |
Ayrton, AD; Baldwin, SJ; Bloomer, JC; Chenery, RJ; Clarke, SE; Smith, GJ | 1 |
Chiba, K; Echizen, H; Ishizaki, T; Tani, M; Yoshimoto, K | 1 |
Birkett, DJ; Miners, JO; Rees, DL; Valente, L; Veronese, ME | 1 |
Birkett, DJ; Doecke, CJ; Gasser, R; Mackenzie, PI; McManus, ME; Meyer, UA; Miners, JO; Rees, DL; Veronese, ME | 1 |
Feron, VJ; Groene, EM; Horbach, GJ; Kappers, WA; Kleij, LA; Witkamp, RF; Zweers-Zeilmaker, WM | 1 |
Gonzalez, FJ; Korzekwa, KR; Marra, C; Tracy, TS; Wrighton, SA | 1 |
Horbach, GJ; Witkamp, RF; Zweers-Zeilmaker, WM | 1 |
Shimada, T; Yamazaki, H | 1 |
Inoue, K; Kamataki, T; Kodama, T; Nagashima, K; Nakamura, K; Shimada, N; Shimizu, T; Yokoi, T | 1 |
Back, DJ; Eagling, VA; Tjia, JF | 1 |
Inoue, T; Kuroiwa, Y; Nakajima, M; Shimada, N; Tokudome, S; Yamamoto, T | 1 |
Inoue, K; Shimada, T; Yamazaki, H | 1 |
Ball, DE; Kamali, F; McLaughlin, WS; Seymour, RA | 1 |
Ito, K; Kanamitsu, S; Sugiyama, Y | 1 |
CHRISTENSEN, LK; HANSEN, JM; KRISTENSEN, M | 1 |
Chan, SL; Or, PM; Yeung, JH | 1 |
Huang, HH; Lin, LH; Zhang, P; Zhong, DF | 1 |
Pickova, J; Vestergren, AS; Zamaratskaia, G; Zlabek, V | 1 |
Burmistrova, OA; Poloznikov, AA; Sakharov, DA; Shkurnikov, MY; Zakhariants, AA | 1 |
Chappell, J; Kellie Turner, P; Ng, WT; Perkins, EJ; Posada, M; Twelves, C | 1 |
40 other study(ies) available for sulfaphenazole and tolbutamide
Article | Year |
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A refined 3-dimensional QSAR of cytochrome P450 2C9: computational predictions of drug interactions.
Topics: Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Ligands; Models, Biological; Models, Molecular; Protein Binding; Reproducibility of Results; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Sulfaphenazole; Sulfonamides; Warfarin | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
Topics: Amides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Oxidoreductases; Quantitative Structure-Activity Relationship; Sterol 14-Demethylase | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors.
Topics: Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Molecular Structure; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Displacement of tolbutamide, glibencalmide and chlorpropamide from serum albumin by anionic drugs.
Topics: Acetaminophen; Animals; Cattle; Chlorpropamide; Dialysis; Glyburide; Humans; Phenylbutazone; Protein Binding; Salicylates; Serum Albumin; Serum Albumin, Bovine; Sulfaphenazole; Tolbutamide; Warfarin | 1976 |
Tolbutamide-sulfaphenazole interaction in rabbits.
Topics: Animals; Drug Interactions; Kinetics; Male; Rabbits; Sulfaphenazole; Tolbutamide | 1977 |
Mechanisms of inhibition of tolbutamide metabolism: phenylbutazone, oxyphenbutazone, sulfaphenazole.
Topics: Adult; Depression, Chemical; Drug Interactions; Half-Life; Humans; Male; Oxyphenbutazone; Phenylbutazone; Sulfaphenazole; Time Factors; Tolbutamide | 1977 |
Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9.
Topics: Animals; Base Sequence; Cell Line; Cytochrome P-450 Enzyme System; DNA; Gene Library; Humans; Hydroxylation; Kinetics; Liver; Microsomes, Liver; Molecular Sequence Data; Oligonucleotide Probes; Phenytoin; Recombinant Proteins; Substrate Specificity; Sulfaphenazole; Tolbutamide; Transfection | 1991 |
Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes.
Topics: Binding, Competitive; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Immunoglobulin G; In Vitro Techniques; Kinetics; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; Phenytoin; Sulfaphenazole; Tolbutamide | 1991 |
Validation of the tolbutamide metabolic ratio for population screening with use of sulfaphenazole to produce model phenotypic poor metabolizers.
Topics: Administration, Oral; Adult; Chromatography; Female; Half-Life; Humans; Hydroxylation; Male; Phenotype; Random Allocation; Sulfaphenazole; Tolbutamide | 1990 |
Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae.
Topics: Catalysis; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Electrophoresis; Gene Expression Regulation; Genetic Vectors; Hexobarbital; Humans; Liver; Mephenytoin; Mixed Function Oxygenases; Oxidation-Reduction; Plasmids; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Sulfaphenazole; Tolbutamide | 1989 |
Selective inhibition of drug oxidation after simultaneous administration of two probe drugs, antipyrine and tolbutamide.
Topics: Adult; Antipyrine; Cimetidine; Female; Half-Life; Humans; Male; Oxidation-Reduction; Pharmaceutical Preparations; Primaquine; Sulfaphenazole; Tolbutamide | 1988 |
[Dangers in drug combinations].
Topics: Dicumarol; Dosage Forms; Drug Antagonism; Drug Interactions; Drug Synergism; Erythroblastosis, Fetal; Female; Humans; Isocarboxazid; Microsomes, Liver; Phenylbutazone; Pregnancy; Sulfaphenazole; Sulfonamides; Tolbutamide | 1972 |
[Drug induced changes of the blood glucose lowering effect of oral hypoglycemic agents].
Topics: Aged; Blood Glucose; Chlorpropamide; Chromatography, Thin Layer; Dicumarol; Drug Synergism; Humans; Hypoglycemia; Hypoglycemic Agents; Liver; Protein Binding; Sulfaphenazole; Sulfur Isotopes; Tolbutamide | 1969 |
Potentiating effects of drugs on the binding of glibenclamide to pancreatic beta cells.
Topics: Animals; Binding Sites; Drug Synergism; Female; Glyburide; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Phenylbutazone; Serum Albumin; Sucrose; Sulfaphenazole; Sulfisomidine; Sulfisoxazole; Sulfonamides; Tolbutamide | 1974 |
Effect of sulfaphenazole on tolbutamide distribution in rabbits: analysis of interspecies differences in tissue distribution of tolbutamide.
Topics: Animals; Male; Rabbits; Rats; Species Specificity; Sulfaphenazole; Tissue Distribution; Tolbutamide | 1984 |
Prediction of drug-drug interaction from in vitro plasma protein binding and metabolism. A study of tolbutamide-sulfonamide interaction in rats.
Topics: Animals; Blood Proteins; Drug Interactions; Half-Life; Male; Mathematics; Metabolic Clearance Rate; Rats; Rats, Inbred Strains; Sulfadimethoxine; Sulfamethoxazole; Sulfaphenazole; Sulfonamides; Tolbutamide | 1981 |
Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Female; Humans; Ketoconazole; Male; Microsomes, Liver; Mixed Function Oxygenases; Steroid Hydroxylases; Sulfaphenazole; Tolbutamide | 1995 |
Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.
Topics: Aged; Benzoflavones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Ditiocarb; Female; Humans; Hydroxylation; In Vitro Techniques; Isoenzymes; Male; Mephenytoin; Microsomes, Liver; Middle Aged; Oxazines; Phenacetin; Propranolol; Quinidine; Recombinant Proteins; Stereoisomerism; Substrate Specificity; Sulfaphenazole; Tolbutamide; Troleandomycin | 1995 |
Human hepatic cytochrome P450 2C9 catalyzes the rate-limiting pathway of torsemide metabolism.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diuretics; Humans; In Vitro Techniques; Kinetics; Liver; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sulfaphenazole; Sulfonamides; Tolbutamide; Torsemide | 1995 |
Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily.
Topics: Amino Acid Sequence; Aryl Hydrocarbon Hydroxylases; Base Sequence; Cell Line; Cytochrome P-450 Enzyme System; DNA; Humans; Hydroxylation; Isoenzymes; Kinetics; Liver; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sulfaphenazole; Tolbutamide; Transfection | 1993 |
Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Cell Line; Cricetinae; Cricetulus; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Diclofenac; Drug Interactions; Enzyme Inhibitors; Flurbiprofen; Gene Expression; Humans; Hydroxylation; Ketoprofen; Lung; Methylation; Mixed Function Oxygenases; Phenylbutazone; Sulfaphenazole; Tolbutamide; Transfection | 1996 |
Involvement of multiple cytochrome P450 isoforms in naproxen O-demethylation.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dealkylation; Humans; In Vitro Techniques; Microsomes, Liver; Naproxen; Piroxicam; Sulfaphenazole; Tolbutamide; Transfection; Vaccinia virus; Warfarin | 1997 |
Differential inhibitory effects of phenytoin, diclofenac, phenylbutazone and a series of sulfonamides on hepatic cytochrome P4502C activity in vitro, and correlation with some molecular descriptors in the dwarf goat (Caprus hircus aegagrus).
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme Inhibitors; Female; Goats; Hydroxylation; Kinetics; Liver; Microsomes, Liver; Phenylbutazone; Phenytoin; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sulfaphenazole; Sulfonamides; Tolbutamide | 1997 |
Human liver cytochrome P450 enzymes involved in the 7-hydroxylation of R- and S-warfarin enantiomers.
Topics: Animals; Anticoagulants; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Stereoisomerism; Sulfaphenazole; Tolbutamide; Warfarin | 1997 |
Oxidation of histamine H1 antagonist mequitazine is catalyzed by cytochrome P450 2D6 in human liver microsomes.
Topics: 1-Propanol; Caffeine; Chlorzoxazone; Coumarins; Cyclosporine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Histamine H1 Antagonists; Humans; Microsomes, Liver; Mixed Function Oxygenases; Phenacetin; Phenothiazines; Precipitin Tests; Sulfaphenazole; Tolbutamide | 1998 |
Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes.
Topics: Animals; Chlorzoxazone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Enzyme Inhibitors; Humans; Ketoconazole; Kinetics; Male; Microsomes, Liver; Phenacetin; Rats; Rats, Wistar; Substrate Specificity; Sulfaphenazole; Testosterone; Theophylline; Tolbutamide | 1998 |
Cytochrome P450 2C9 catalyzes indomethacin O-demethylation in human liver microsomes.
Topics: Alkylation; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indomethacin; Isoenzymes; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Molecular Structure; Oxidoreductases, O-Demethylating; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sulfaphenazole; Tolbutamide; Tumor Cells, Cultured; Warfarin | 1998 |
Roles of two allelic variants (Arg144Cys and Ile359Leu) of cytochrome P4502C9 in the oxidation of tolbutamide and warfarin by human liver microsomes.
Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Genotype; Humans; Hydroxylation; Japan; Kinetics; Microsomes, Liver; Polymorphism, Genetic; Recombinant Proteins; Stereoisomerism; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sulfaphenazole; Tolbutamide; Warfarin | 1998 |
Phenytoin metabolism to 5-(4-hydroxyphenyl)-5-phenylhydantoin (HPPH) in man, cat and rat in vitro and in vivo, and susceptibility to phenytoin-induced gingival overgrowth.
Topics: Adult; Aged; Animals; Anticonvulsants; Area Under Curve; Biotransformation; Cats; Chlorophyll; Chromatography, High Pressure Liquid; Epilepsy; Female; Gingival Overgrowth; Humans; Hydroxylation; Liver; Male; Microsomes; Middle Aged; Phenytoin; Photosensitizing Agents; Rats; Rats, Wistar; Species Specificity; Statistics, Nonparametric; Sulfaphenazole; Tolbutamide | 1999 |
Quantitative prediction of in vivo drug-drug interactions from in vitro data based on physiological pharmacokinetics: use of maximum unbound concentration of inhibitor at the inlet to the liver.
Topics: Animals; Anti-Infective Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Humans; Hypoglycemic Agents; Liver; Models, Biological; Predictive Value of Tests; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sulfaphenazole; Tolbutamide | 2000 |
SULPHAPHENAZOLE-INDUCED HYPOGLYCAEMIC ATTACKS IN TOLBUTAMIDE-TREATED DIABETICS.
Topics: Aged; Diabetes Mellitus; Geriatrics; Humans; Hypoglycemia; Hypoglycemic Agents; Phenylbutazone; Sulfadiazine; Sulfadimethoxine; Sulfaphenazole; Tolbutamide | 1963 |
Polysaccharide peptides from COV-1 strain of Coriolus versicolor inhibit tolbutamide 4-hydroxylation in the rat in vitro and in vivo.
Topics: Animals; Basidiomycota; Carbohydrate Sequence; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hydroxylation; Hypoglycemic Agents; Isoenzymes; Liver; Male; Microsomes, Liver; Molecular Sequence Data; Proteoglycans; Rats; Rats, Sprague-Dawley; Sulfaphenazole; Tolbutamide | 2006 |
[The inhibition of CYP2C9 isoenzyme in Cunninghamella blakesleeana AS 3. 910].
Topics: Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Catalysis; Chromatography, High Pressure Liquid; Cunninghamella; Cytochrome P-450 CYP2C9; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Fungal Proteins; Indomethacin; Isoenzymes; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Sulfaphenazole; Tolbutamide; Valproic Acid | 2006 |
Tolbutamide hydroxylation by hepatic microsomes from Atlantic salmon (Salmo salar L.).
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diclofenac; Dioxoles; Ellipticines; Fish Proteins; Fluconazole; Hydroxylation; Ketoconazole; Kinetics; Lignans; Microsomes, Liver; Oxazines; Salmo salar; Sulfaphenazole; Tolbutamide | 2012 |
Development of a Specific Substrate-Inhibitor Panel (Liver-on-a-Chip) for Evaluation of Cytochrome P450 Activity.
Topics: Bupropion; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Humans; Ketoconazole; Lab-On-A-Chip Devices; Liver; Mass Spectrometry; Mephenytoin; Microsomes, Liver; Omeprazole; Phencyclidine; Substrate Specificity; Sulfaphenazole; Testosterone; Tolbutamide | 2016 |
Physiologically Based Pharmacokinetic Modelling of Cytochrome P450 2C9-Related Tolbutamide Drug Interactions with Sulfaphenazole and Tasisulam.
Topics: Benzamides; Clinical Trials as Topic; Cytochrome P-450 CYP2C9; Drug Interactions; Humans; Models, Biological; Sulfaphenazole; Sulfonamides; Tolbutamide | 2018 |