sulfanilamide has been researched along with acetazolamide in 133 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 36 (27.07) | 18.7374 |
1990's | 3 (2.26) | 18.2507 |
2000's | 35 (26.32) | 29.6817 |
2010's | 54 (40.60) | 24.3611 |
2020's | 5 (3.76) | 2.80 |
Authors | Studies |
---|---|
Briganti, F; Menabuoni, L; Mincione, F; Mincione, G; Scozzafava, A; Supuran, CT | 2 |
Briganti, F; Ilies, MA; Scozzafava, A; Supuran, CT | 1 |
Menabuoni, L; Mincione, F; Mincione, G; Scozzafava, A; Supuran, CT | 1 |
Menabuoni, L; Mincione, F; Scozzafava, A; Supuran, CT | 1 |
Franchi, M; Gallori, E; Pastorek, J; Pastorekova, S; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Caproiu, MT; Ilies, M; Ilies, MA; Pastorek, J; Pastorekova, S; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Casini, A; Mincione, F; Montero, JL; Scozzafava, A; Starnotti, M; Supuran, CT; Winum, JY | 1 |
Antel, J; Franchi, M; Gallori, E; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Jaiswal, M; Khadikar, PV; Scozzafava, A; Supuran, CT | 1 |
Casini, A; Lehtonen, JM; Parkkila, S; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Fasolis, G; Garaj, V; Innocenti, A; Montero, JL; Puccetti, L; Scozzafava, A; Supuran, CT; Vullo, D; Winum, JY | 1 |
Casini, A; Ferry, JG; Innocenti, A; Scozzafava, A; Supuran, CT; Zimmerman, S | 1 |
Durgun, M; Emul, M; Innocenti, A; Scozzafava, A; Supuran, CT; Turkmen, H; Vullo, D; Yilmaztekin, S | 1 |
Innocenti, A; Kaila, K; Ranki, H; Rivera, C; Scozzafava, A; Supuran, CT; Voipio, J; Vullo, D | 1 |
Antel, J; Firnges, MA; Innocenti, A; Scozzafava, A; Supuran, CT; Wurl, M | 1 |
Cecchi, A; Fasolis, G; Gamberi, A; Montero, JL; Puccetti, L; Scozzafava, A; Supuran, CT; Winum, JY | 1 |
Cecchi, A; Innocenti, A; Montero, JL; Scozzafava, A; Supuran, CT; Winum, JY | 1 |
Innocenti, A; Mastrolorenzo, A; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D | 2 |
Bacciottini, L; Casini, A; Masini, E; Mincione, F; Scozzafava, A; Scrivanti, C; Starnotti, M; Supuran, CT; Vullo, D | 1 |
Arslan, O; Fasolis, G; Ozensoy, O; Puccetti, L; Scozzafava, A; Supuran, CT | 1 |
Minakuchi, T; Morimoto, K; Nishimori, I; Onishi, S; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Minakuchi, T; Morimoto, K; Nishimori, I; Onishi, S; Sano, S; Scozzafava, A; Supuran, CT; Takeuchi, H; Vullo, D | 1 |
Minakuchi, T; Nishimori, I; Onishi, S; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Kohsaki, T; Minakuchi, T; Nishimori, I; Onishi, S; Scozzafava, A; Supuran, CT; Takeuchi, H; Vullo, D | 1 |
Cecchi, A; Minakuchi, T; Nishimori, I; Onishi, S; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Innocenti, A; Montero, JL; Rami, M; Scozzafava, A; Supuran, CT; Winum, JY | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Arslan, O; Aydin, M; Guler, OO; Innocenti, A; Isik, S; Kockar, F; Scozzafava, A; Supuran, CT | 1 |
Hilvo, M; Innocenti, A; Kulomaa, MS; Parkkila, S; Salzano, AM; Scaloni, A; Scozzafava, A; Supuran, CT | 1 |
Minakuchi, T; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D | 2 |
Innocenti, A; Minakuchi, T; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Hall, RA; Innocenti, A; Mühlschlegel, FA; Schlicker, C; Scozzafava, A; Steegborn, C; Supuran, CT | 1 |
Bertucci, A; Innocenti, A; Scozzafava, A; Supuran, CT; Tambutté, S; Zoccola, D | 2 |
Carta, F; Covarrubias, AS; Jones, TA; Maresca, A; Mowbray, SL; Supuran, CT | 1 |
Davis, RA; Innocenti, A; Poulsen, SA; Supuran, CT | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Innocenti, A; Parkkila, S; Scozzafava, A; Supuran, CT; Temperini, C | 1 |
Joseph, P; Köhler, S; Minakuchi, T; Montero, JL; Nishimori, I; Ouahrani-Bettache, S; Scozzafava, A; Supuran, CT; Turtaut, F; Vullo, D; Winum, JY | 1 |
Köhler, S; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D; Winum, JY | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Arslan, O; Aydin, M; Güler, OO; Işik, S; Kockar, F; Maresca, A; Sinan, S; Supuran, CT; Turan, Y; Turkoglu, S | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Carta, F; Pacchiano, F; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Joseph, P; Köhler, S; Minakuchi, T; Montero, JL; Nishimori, I; Ouahrani-Bettache, S; Scozzafava, A; Supuran, CT; Vullo, D; Winum, JY | 1 |
Davis, RA; Hall, RA; Hofmann, A; Innocenti, A; Mühlschlegel, FA; Osman, A; Poulsen, SA; Supuran, CT; Vullo, D | 1 |
Maresca, A; Montero, JL; Rami, M; Scozzafava, A; Smaine, FZ; Supuran, CT; Winum, JY | 1 |
Basar, E; Bülbül, M; Cakir, E; Kaya, M; Tunca, E | 1 |
Innocenti, A; Knaus, EE; Scozzafava, A; Supuran, CT | 1 |
Alp, C; Alp, NA; Erdem, D; Gültekin, MS; Küfrevioğlu, Öİ; Özsoy, Ş; Şentürk, M; Supuran, CT | 1 |
Jackson, DJ; Ohradanova, A; Pastorek, J; Pastorekova, S; Supuran, CT; Vullo, D; Wörheide, G | 1 |
Bornaghi, LF; Innocenti, A; Lopez, M; Moeker, J; Poulsen, SA; Rossit, S; Supuran, CT; Teruya, K; Wilkinson, BL | 1 |
Alper, M; Arslan, O; Işık, S; Kockar, F; Maresca, A; Ozensoy, O; Sinan, S; Supuran, CT; Turkoglu, S | 1 |
Hewitson, KS; Mastrolorenzo, A; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Capasso, C; Carginale, V; Luca, VD; Rossi, M; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Isik, S; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Capaci Rodrigues, G; Capasso, C; Pan, P; Parkkila, S; Scozzafava, A; Supuran, CT; Tolvanen, ME; Vermelho, AB | 1 |
Capasso, C; Leewattanapasuk, W; Mastrolorenzo, A; Mühlschlegel, FA; Supuran, CT; Vullo, D | 1 |
Duan, YT; Qin, YJ; Qiu, HY; Sang, YL; Wang, PF; Wang, YT; Wang, ZC; Wen, Q; Yang, YA; Zhang, X; Zhu, HL | 1 |
Capasso, C; Corte-Real, S; Pan, P; Parkkila, S; Rodrigues, Ide A; Salonen, T; Supuran, CT; Syrjänen, L; Vermelho, AB; Vullo, D | 1 |
Bozdag, M; Carta, F; Ferraroni, M; Nuti, E; Rossello, A; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Alothman, Z; Capasso, C; De Luca, V; Del Prete, S; Osman, SM; Scozzafava, A; Supuran, CT; Vullo, D | 2 |
Balboni, G; Congiu, C; Onnis, V; Supuran, CT | 1 |
Barboiu, M; Cristian, A; Nasr, G; Supuran, CT; Vullo, D; Winum, JY | 1 |
Capasso, C; Minakuchi, T; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
AlOthman, Z; Capasso, C; Osman, SM; Prete, SD; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Andrews, KT; Capasso, C; Del Prete, S; Fisher, GM; Poulsen, SA; Supuran, CT; Vullo, D | 1 |
Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Scozzafava, A; Supuran, CT; Vullo, D | 2 |
Kuuslahti, M; Parkkila, S; Supuran, CT; Syrjänen, L; Tolvanen, M; Vullo, D | 1 |
Capasso, C; Dedeoglu, N; DeLuca, V; Isik, S; Kockar, F; Supuran, CT; Yildirim, H | 1 |
Bhatt, A; Mahon, BP; McKenna, R; Supuran, CT; Vullo, D | 1 |
AlOthman, Z; Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Osman, SM; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
AlOthman, Z; Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Ferraroni, M; Osman, SM; Supuran, CT; Vullo, D | 1 |
Aşık, A; Beldüz, AO; Çanakçı, S; Çolak, DN; Eminoğlu, A; Supuran, CT; Vullo, D | 1 |
AlOthman, Z; Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Osman, SM; Supuran, CT; Vullo, D | 2 |
Bao, Y; Chang, XW; Cheng, MS; Guo, C; Hou, Z; Lin, B; Liu, Y; Wang, ZJ; Wei, GF; Yan, HN; Zhang, M; Zhang, XX | 1 |
Angapelly, S; Angeli, A; Arifuddin, M; Capasso, C; Del Prete, S; Ramya, PVS; Supuran, CT | 1 |
Bua, S; Kopecka, J; Mujumdar, P; Poulsen, SA; Riganti, C; Supuran, CT | 1 |
Angeli, A; Berrino, E; Capasso, C; De Luca, L; Del Prete, S; Gitto, R; Mancuso, F; Supuran, CT | 1 |
Beteck, RM; Jesumoroti, OJ; Legoabe, LJ; Patel, OPS | 1 |
Aguenaou, H; Colin, DA | 1 |
MAREN, TH | 2 |
FRIEDBERG, CK; HALPERN, M; MINOR, JB; TAYMOR, R | 1 |
BELSKY, H | 1 |
BUSO, R; SABATER, J; SUAREZ, RM | 1 |
MAREN, TH; MAYER, E; WADSWORTH, BC | 1 |
BONANNO, S; REITANO, U | 1 |
ANDREUCCI, G; CORDOVA, C; COSTA, C; PALMA, G | 1 |
FISHER, ER; GLUSHIEN, AS | 1 |
COCCHI, P | 1 |
HERKEN, H; WILUTZKY, H | 1 |
ARIENS, EJ; SIMONIS, AM | 1 |
JOHNSON, MJ; MITCHELL, DF | 1 |
FORD, RV; MOYER, JH; SPURR, CL | 1 |
NOCKER, J; SCHLEUSING, G | 1 |
SALISBURY, GW; VANDEMARK, NL | 1 |
HAZARD, R; PIGNARD, P | 1 |
OTTO, H | 1 |
HEJTMANCIK, MR; HERRMANN, GR; KROETZ, FW | 1 |
RICHTERICH, R | 1 |
BARRETT, WE; PLUMMER, AJ; RUTLEDGE, RA; SHEPPARD, H | 1 |
CHART, JJ; GAUNT, R; RENZI, AA | 1 |
GROBIN, W | 1 |
GOERES, E; HILGETAG, G; JUNG, F | 1 |
AZZOLINI, G; MARRO, F | 1 |
AZZOLINI, G; GADOLINI, G; MARRO, F | 1 |
COZZALI, G; FRASCARELLI, R; LUCIDI, E | 1 |
HENTRICH, K | 1 |
FELLNER, SK | 1 |
KORE, R; MCINTOSH, HW; SERAGLIA, M; UHLEMANN, I | 1 |
ARMASCRUZ, R; GOMEZ, R; MARDONES, J; PLAZADELOSREYES, M | 1 |
HIRASAWA, Y; KINOSHITA, Y | 1 |
LASSEN, JB; NIELSEN, OE | 1 |
CASTLES, TR; WILLIAMSON, HE | 1 |
IASTREBOVA, LP; KIRPISHCHIKOVA, TP | 1 |
Demir, N; Demir, Y; Nadaroğlu, H | 1 |
Dincer, B; Karahalil, F; Kolayli, S; Sahin, H; Supuran, CT | 1 |
Scozzafava, A; Supuran, CT | 1 |
Al-Rashida, M; Hamayoun, M; Iqbal, J; Mumtaz, A; Saeed, A | 1 |
Berg, S; Isupov, MN; James, P; Kotlar, HK; Lioliou, M; Littlechild, JA; Saneei, V; Sayer, C | 1 |
Supuran, CT | 2 |
Angeli, A; Bucolo, F; Capasso, C; De Luca, L; De Luca, V; Gitto, R; Mancuso, F; Supuran, CT | 1 |
Aisala, H; Aspatwar, A; Bonardi, A; Lumme, J; Parkkila, S; Primmer, CR; Supuran, CT; Zueva, K | 1 |
Angeli, A; Paoletti, N; Supuran, CT | 1 |
6 review(s) available for sulfanilamide and acetazolamide
Article | Year |
---|---|
Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antiprotozoal Agents; Drug Development; Humans; Hypoglycemic Agents; Metronidazole | 2021 |
[PROGRESS OF CARBONIC ANHYDRASE INHIBITORS].
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dogs; Enzyme Inhibitors; Pharmacology; Research; Sulfanilamide; Sulfanilamides; Sulfonamides | 1964 |
Glaucoma and the applications of carbonic anhydrase inhibitors.
Topics: Acetazolamide; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IV; Carbonic Anhydrases; Glaucoma; Humans; Intraocular Pressure; Nitric Oxide; Structure-Activity Relationship; Sulfanilamide; Sulfanilamides; Sulfonamides; Thiazines | 2014 |
Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors.
Topics: Acetazolamide; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Antibodies, Monoclonal; Anticonvulsants; Antineoplastic Agents; Benzodiazepines; Carbonic Anhydrase Inhibitors; Celecoxib; Clinical Trials as Topic; Contraindications; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Fructose; Humans; Isoxazoles; Methazolamide; Phenobarbital; Sulfanilamide; Sulfanilamides; Sulfonamides; Sulfonic Acids; Thiazines; Thiophenes; Topiramate; Zonisamide | 2016 |
Carbonic anhydrase inhibition and the management of neuropathic pain.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Neuralgia; Sulfanilamide; Sulfanilamides | 2016 |
Five-Membered Heterocyclic Sulfonamides as Carbonic Anhydrase Inhibitors.
Topics: Acetazolamide; Anticonvulsants; Carbonic Anhydrase Inhibitors; Dermatologic Agents; Structure-Activity Relationship; Sulfanilamide; Sulfonamides | 2023 |
127 other study(ies) available for sulfanilamide and acetazolamide
Article | Year |
---|---|
Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring?
Topics: Administration, Topical; Animals; Aqueous Humor; Benzene Derivatives; Carbonic Anhydrase Inhibitors; Cattle; Eye; Humans; Intraocular Pressure; Isoenzymes; Male; Ophthalmic Solutions; Pyridines; Rabbits; Solubility; Structure-Activity Relationship; Sulfonamides; Thiadiazoles; Tissue Distribution | 1999 |
Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Membrane Permeability; Cornea; Delayed-Action Preparations; Dipeptides; Disease Models, Animal; Glaucoma; Humans; Intraocular Pressure; Isoenzymes; Models, Molecular; Rabbits; Solubility; Sulfonamides; Time Factors | 1999 |
Carbonic anhydrase inhibitors: synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes.
Topics: Animals; Carbonic Anhydrase Inhibitors; Cattle; Cell Membrane Permeability; Cytosol; Erythrocyte Membrane; Humans; Isoenzymes; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Sulfonamides | 2000 |
Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Intraocular Pressure; Pentetic Acid; Quantitative Structure-Activity Relationship; Rabbits; Sulfonamides; Zinc | 2001 |
Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.
Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chelating Agents; Chloroform; Chromatography, High Pressure Liquid; Cornea; DNA, Complementary; Edetic Acid; Enzyme Inhibitors; Escherichia coli; Glaucoma; Humans; Hydrogen-Ion Concentration; Imino Acids; Kinetics; Male; Models, Chemical; Nitrilotriacetic Acid; Pentetic Acid; Pressure; Rabbits; Sulfonamides; Temperature; Time Factors; Ultraviolet Rays; Water | 2002 |
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.
Topics: Animals; Antigens, Neoplasm; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cattle; Heterocyclic Compounds; Humans; Hydrocarbons, Aromatic; Isoenzymes; Kinetics; Neoplasm Proteins; Neoplasms; Structure-Activity Relationship; Sulfonamides | 2003 |
Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Benzene Derivatives; Bromine; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase IV; Carbonic Anhydrase IX; Carbonic Anhydrases; Chlorine; Enzyme Inhibitors; Humans; Iodine; Neoplasm Proteins; Structure-Activity Relationship; Sulfanilamides; Sulfonamides | 2003 |
Carbonic anhydrase inhibitors: N-(p-sulfamoylphenyl)-alpha-D-glycopyranosylamines as topically acting antiglaucoma agents in hypertensive rabbits.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Glaucoma; Hypertension; Intraocular Pressure; Male; Monosaccharides; Rabbits; Sulfanilamides | 2004 |
Carbonic anhydrase inhibitors. Inhibition of mitochondrial isozyme V with aromatic and heterocyclic sulfonamides.
Topics: Animals; Benzene Derivatives; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase V; Coumarins; Mice; Mitochondria; Structure-Activity Relationship; Sulfonamides; Thiadiazoles | 2004 |
Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides.
Topics: Antigens, Neoplasm; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Isoenzymes; Quantitative Structure-Activity Relationship; Sulfonamides | 2004 |
Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design.
Topics: Amino Acid Sequence; Animals; Carbonic Anhydrase Inhibitors; Cytosol; Drug Design; Humans; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Molecular Sequence Data; Neoplasms; Rats; Structure-Activity Relationship; Sulfonamides | 2004 |
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cytosol; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Sulfonamides; Triazines | 2004 |
Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides.
Topics: Archaea; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Isoenzymes; Molecular Structure; Structure-Activity Relationship; Sulfonamides | 2004 |
Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.
Topics: Acetazolamide; Amines; Biomarkers, Tumor; Carbonic Anhydrase Inhibitors; Catalysis; Cytosol; Heterocyclic Compounds; Humans; Isoenzymes; Morpholines; Piperazine; Piperazines; Piperidines; Structure-Activity Relationship; Sulfanilamide; Sulfanilamides | 2005 |
Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.
Topics: Anticonvulsants; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Heterocyclic Compounds; Humans; Hydrocarbons, Aromatic; Isoenzymes; Protein Subunits; Structure-Activity Relationship; Sulfonamides | 2005 |
Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides.
Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IV; Cattle; Dose-Response Relationship, Drug; Humans; Isoenzymes; Kinetics; Membrane Proteins; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids | 2005 |
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.
Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Catalytic Domain; Cytosol; Humans; Kinetics; Neoplasms; Structure-Activity Relationship; Sulfonamides; Urea | 2005 |
Carbonic anhydrase inhibitors. Synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with boron-containing sulfonamides, sulfamides, and sulfamates: toward agents for boron neutron capture therapy of hypoxic tumo
Topics: Antigens, Neoplasm; Boron Compounds; Boron Neutron Capture Therapy; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Humans; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids | 2005 |
Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Fructose; Humans; Kinetics; Membrane Proteins; Protein Binding; Structure-Activity Relationship; Sulfonamides; Topiramate | 2005 |
Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma.
Topics: Animals; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Disease Models, Animal; Drug Design; Glaucoma; Intraocular Pressure; Rabbits; Structure-Activity Relationship; Sulfonamides | 2005 |
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozymes IX and XII with a library of aromatic and heteroaromatic sulfonamides.
Topics: Antigens, Neoplasm; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Humans; Neoplasm Proteins; Structure-Activity Relationship; Sulfonamides | 2005 |
Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase V; Catalysis; Cloning, Molecular; Humans; Isoenzymes; Kinetics; Mitochondria; Molecular Sequence Data; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids | 2005 |
Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.
Topics: Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Helicobacter pylori; Humans; Hydrogen-Ion Concentration; Structure-Activity Relationship; Sulfonamides | 2006 |
Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; DNA, Bacterial; Gastric Mucosa; Gastritis; Helicobacter pylori; Humans; Molecular Sequence Data; Polymorphism, Genetic; Stomach Neoplasms; Stomach Ulcer; Sulfonamides; Sulfonic Acids | 2006 |
Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalysis; Cloning, Molecular; DNA; Humans; Isoenzymes; Molecular Sequence Data; Protein Subunits; Sequence Homology, Amino Acid; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids | 2007 |
Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chemistry, Pharmaceutical; Cloning, Molecular; Drug Design; Enzyme Inhibitors; Helicobacter pylori; Humans; Molecular Sequence Data; Recombinant Proteins; Sequence Homology, Amino Acid; Stomach Neoplasms; Stomach Ulcer; Sulfonamides | 2007 |
Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides.
Topics: Amino Acid Sequence; Carbonic Anhydrase III; Carbonic Anhydrase Inhibitors; Cloning, Molecular; Cytosol; Enzyme Activation; Humans; Isoenzymes; Kinetics; Molecular Sequence Data; Recombinant Proteins; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids | 2007 |
Carbonic anhydrase inhibitors: copper(II) complexes of polyamino-polycarboxylamido aromatic/heterocyclic sulfonamides are very potent inhibitors of the tumor-associated isoforms IX and XII.
Topics: Amines; Carbonic Anhydrase Inhibitors; Copper; Heterocyclic Compounds; Isoenzymes; Neoplasms; Sulfonamides | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates.
Topics: Amino Acid Sequence; Antifungal Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Kinetics; Molecular Sequence Data; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Sulfonamides; Sulfonic Acids | 2009 |
Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV.
Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Isoenzymes; Kidney; Mice; Protein Processing, Post-Translational | 2009 |
Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalysis; Cloning, Molecular; Drug Resistance, Multiple, Bacterial; Humans; Molecular Sequence Data; Mycobacterium tuberculosis; Recombinant Proteins; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids | 2009 |
Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis.
Topics: Amino Acid Sequence; Biocatalysis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Molecular Sequence Data; Mycobacterium tuberculosis; Sulfonamides; Sulfonic Acids | 2009 |
Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides.
Topics: Amino Acid Sequence; Antifungal Agents; Bacterial Proteins; Candida albicans; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cryptococcus neoformans; Helicobacter pylori; Humans; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Sequence Alignment; Structure-Activity Relationship; Sulfonamides | 2009 |
Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides.
Topics: Amino Acid Sequence; Animals; Anthozoa; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Molecular Sequence Data; Molecular Structure; Recombinant Proteins; Sequence Alignment; Sulfonamides | 2009 |
Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalytic Domain; Drug Design; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2009 |
Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library.
Topics: Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cytosol; Humans; Isoenzymes; Mitochondria; Molecular Structure; Phenols; Structure-Activity Relationship | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors.
Topics: Acetamides; Binding Sites; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Coumarins; Crystallography, X-Ray; Humans; Lacosamide; Structure-Activity Relationship | 2010 |
Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brucella suis; Brucellosis; Carbonic Anhydrases; Cloning, Molecular; DNA, Bacterial; Humans; Kinetics; Molecular Sequence Data; Phylogeny; Polymerase Chain Reaction; Sequence Alignment; Sequence Analysis, DNA; Structure-Activity Relationship; Sulfonamides | 2010 |
Inhibition studies of a beta-carbonic anhydrase from Brucella suis with a series of water soluble glycosyl sulfanilamides.
Topics: Amino Acid Sequence; Brucella suis; Carbohydrates; Carbonic Anhydrase I; Carbonic Anhydrase Inhibitors; Humans; Kinetics; Molecular Sequence Data; Sequence Alignment; Structure-Activity Relationship; Sulfanilamides; Water | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Binding Sites; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Cell Line, Tumor; Computer Simulation; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Sulfonamides | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Inhibition of β-carbonic anhydrases with ureido-substituted benzenesulfonamides.
Topics: Benzenesulfonamides; Candida albicans; Carbonic Anhydrase II; Enzyme Inhibitors; Humans; Mycobacterium tuberculosis; Structure-Activity Relationship; Sulfonamides | 2011 |
Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.
Topics: Animals; Anions; Anthozoa; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Structure-Activity Relationship; Sulfonamides | 2011 |
A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth.
Topics: Anti-Bacterial Agents; Brucella suis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Drug Design; Drug Discovery; Inhibitory Concentration 50; Kinetics; Sulfonamides; Sulfonic Acids | 2011 |
Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases.
Topics: Anti-Bacterial Agents; Antifungal Agents; Biological Products; Candida albicans; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalytic Domain; Cryptococcus neoformans; Crystallography, X-Ray; Humans; Hydrogen Bonding; Isoenzymes; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Phenols; Protein Binding; Small Molecule Libraries | 2011 |
Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Boron Compounds; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Enzyme Activation; Humans; Molecular Structure; Neoplasm Proteins; Oxazolidinones; Protein Isoforms; Structure-Activity Relationship; Sulfonamides | 2011 |
Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates.
Topics: Anti-Bacterial Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Salmonella Infections; Salmonella typhimurium; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids | 2011 |
Synthesis and characterization of novel dioxoacridine sulfonamide derivatives as new carbonic anhydrase inhibitors.
Topics: Acridines; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship; Sulfonamides | 2012 |
Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.
Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cytosol; Drug Screening Assays, Antitumor; Humans; Isoenzymes; Molecular Targeted Therapy; Neoplasms; Stereoisomerism; Structure-Activity Relationship; Sulfonamides | 2011 |
Sulfapyridine-like benzenesulfonamide derivatives as inhibitors of carbonic anhydrase isoenzymes I, II and VI.
Topics: Benzenesulfonates; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Electrophoresis, Polyacrylamide Gel; Enzyme Assays; Erythrocytes; Humans; Kinetics; Molecular Mimicry; Molecular Structure; Structure-Activity Relationship; Substrate Specificity; Sulfapyridine; Sulfonamides | 2012 |
Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.
Topics: Amino Acid Sequence; Animals; Carbonic Anhydrases; Cloning, Molecular; Fossils; Humans; Molecular Sequence Data; Porifera; Protein Binding; Sequence Alignment; Sulfonamides; Sulfonic Acids | 2012 |
Design and synthesis of thiourea compounds that inhibit transmembrane anchored carbonic anhydrases.
Topics: Carbohydrates; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Drug Design; Glycoconjugates; Humans; Protein Isoforms; Solubility; Sulfonamides; Thiourea | 2012 |
Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase II: influences on the catalytic activity and affinity for inhibitors.
Topics: Amino Acid Sequence; Amino Acid Substitution; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalytic Domain; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Sulfonamides | 2012 |
Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target.
Topics: Amino Acid Sequence; Animals; Antifungal Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Dermatomycoses; Fungal Proteins; Humans; Isoenzymes; Malassezia; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Recombinant Fusion Proteins; Scalp Dermatoses; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids | 2012 |
The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides.
Topics: Amino Acid Sequence; Bacteria; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Kinetics; Molecular Sequence Data; Phylogeny; Protein Binding; Recombinant Proteins; Sequence Alignment; Sulfonamides | 2013 |
DNA cloning, characterization, and inhibition studies of an α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.
Topics: Amino Acid Sequence; Biocatalysis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; DNA; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Phylogeny; Sequence Homology, Amino Acid; Vibrio cholerae | 2012 |
Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chagas Disease; Cloning, Molecular; Humans; Molecular Sequence Data; Phylogeny; Protozoan Proteins; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfonamides; Thiadiazoles; Trypanocidal Agents; Trypanosoma cruzi | 2013 |
Carbonic anhydrase inhibitors: inhibition of the β-class enzyme from the pathogenic yeast Candida glabrata with sulfonamides, sulfamates and sulfamides.
Topics: Acetazolamide; Amino Acid Sequence; Antifungal Agents; Candida glabrata; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Kinetics; Molecular Sequence Data; Phylogeny; Protein Binding; Sequence Alignment; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids | 2013 |
Sulfonamides containing coumarin moieties selectively and potently inhibit carbonic anhydrases II and IX: design, synthesis, inhibitory activity and 3D-QSAR analysis.
Topics: Antineoplastic Agents; Apoptosis; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IV; Chemistry Techniques, Synthetic; Coumarins; Drug Design; Humans; Isoenzymes; MCF-7 Cells; Melanoma, Experimental; Molecular Docking Simulation; Protein Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Sulfonamides | 2013 |
Cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Leishmania donovani chagasi, the protozoan parasite responsible for leishmaniasis.
Topics: Amino Acid Sequence; Antiprotozoal Agents; Biocatalysis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Leishmania infantum; Leishmaniasis; Molecular Sequence Data | 2013 |
Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Crystallography, X-Ray; Humans; Models, Molecular; Protein Isoforms; Structure-Activity Relationship | 2014 |
Sulfonamide inhibition studies of the δ-carbonic anhydrase from the diatom Thalassiosira weissflogii.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Diatoms; Dose-Response Relationship, Drug; Molecular Structure; Structure-Activity Relationship; Sulfonamides | 2014 |
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Molecular Structure; Porphyromonas gingivalis; Structure-Activity Relationship; Sulfonamides | 2014 |
Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties.
Topics: Butanones; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Imidazoles; Molecular Structure; Structure-Activity Relationship; Sulfanilamides; Thiones; Thiourea | 2014 |
Carbonic anhydrase inhibitors. Inhibition of human cytosolic isoforms I and II with (reduced) Schiff's bases incorporating sulfonamide, carboxylate and carboxymethyl moieties.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Carboxylic Acids; Dose-Response Relationship, Drug; Humans; Isoenzymes; Molecular Structure; Schiff Bases; Structure-Activity Relationship; Sulfonamides | 2014 |
Sulfonamide inhibition studies of two β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Legionella pneumophila; Molecular Sequence Data; Molecular Structure; Sequence Alignment; Structure-Activity Relationship; Sulfonamides | 2014 |
Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: the β-class (PgiCAb) versus the γ-class (PgiCA) enzymes.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Molecular Sequence Data; Molecular Structure; Phylogeny; Porphyromonas gingivalis; Structure-Activity Relationship; Sulfonamides | 2014 |
Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum.
Topics: Antimalarials; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Plasmodium falciparum; Structure-Activity Relationship; Sulfonamides | 2015 |
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Molecular Sequence Data; Nostoc commune; Sequence Alignment; Sulfanilamide; Sulfanilamides; Sulfonamides; Thiazines; Thiophenes | 2015 |
The β-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides.
Topics: Amino Acid Sequence; Animals; Anopheles; Baculoviridae; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Gene Expression; High-Throughput Screening Assays; Insect Proteins; Insecticides; Kinetics; Molecular Sequence Data; Phylogeny; Protons; Recombinant Proteins; Sequence Alignment; Sf9 Cells; Spodoptera; Sulfanilamides | 2015 |
Sulfonamide inhibition study of the β-class carbonic anhydrase from the caries producing pathogen Streptococcus mutans.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Molecular Structure; Phylogeny; Streptococcus mutans; Sulfonamides | 2015 |
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.
Topics: Acclimatization; Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cold Temperature; Humans; Molecular Sequence Data; Phylogeny; Pseudoalteromonas; Sequence Alignment; Sulfonamides | 2015 |
Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA.
Topics: Anti-Bacterial Agents; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Gammaproteobacteria; Molecular Docking Simulation; Sulfonamides | 2016 |
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea.
Topics: Alteromonadaceae; Anti-Bacterial Agents; Bacterial Proteins; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Kinetics; Phylogeny; Protein Binding; Sulfanilamide; Sulfanilamides | 2016 |
Sulfonamide inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.
Topics: Amino Acid Sequence; Base Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cholera; Crystallography, X-Ray; Humans; Models, Molecular; Molecular Sequence Data; Sulfonamides; Vibrio cholerae | 2016 |
Sulfonamide inhibition studies of the β-carbonic anhydrase from the newly discovered bacterium Enterobacter sp. B13.
Topics: Acetazolamide; Benzenesulfonamides; Carbonic Anhydrase I; Carbonic Anhydrase Inhibitors; Enterobacter; Enterobacteriaceae Infections; Humans; Methazolamide; Structure-Activity Relationship; Sulfonamides | 2016 |
Comparison of the sulfonamide inhibition profiles of the α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship; Sulfonamides; Vibrio cholerae | 2016 |
Cloning, expression, purification and sulfonamide inhibition profile of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum.
Topics: Amino Acid Sequence; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Humans; Kinetics; Molecular Sequence Data; Plasmodium falciparum; Protein Isoforms; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Structure-Activity Relationship; Sulfonamides | 2016 |
Dual-tail approach to discovery of novel carbonic anhydrase IX inhibitors by simultaneously matching the hydrophobic and hydrophilic halves of the active site.
Topics: Antineoplastic Agents; Binding Sites; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Cinnamates; Drug Design; Glucosamine; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Molecular Docking Simulation; Protein Binding; Structure-Activity Relationship | 2017 |
Development of sulfonamides incorporating phenylacrylamido functionalities as carbonic anhydrase isoforms I, II, IX and XII inhibitors.
Topics: Amides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Enzyme Activation; Humans; Isoenzymes; Molecular Structure; Structure-Activity Relationship; Sulfonamides | 2017 |
Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Survival; Drug Design; Drug Resistance, Neoplasm; Female; Glioblastoma; Humans; Mice; Mice, Nude; Protein Isoforms; Structure-Activity Relationship; Temozolomide; Transplantation, Heterologous; Tumor Cells, Cultured | 2019 |
In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in
Topics: | 2020 |
Subcellular distribution of carbonic anhydrase in the enterocyte of the rabbit ileum and the Caco-2 cell. Evidence for the presence of two isozymes bound to brush-border membranes.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Membrane; Ileum; Male; Microvilli; Polyethylene Glycols; Rabbits; Sulfanilamide; Sulfanilamides; Temperature; Tumor Cells, Cultured | 1992 |
Pharmacological and renal effects of diamox (6063), a new carbonic anhydrase inhibitor.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Hydro-Lyases; Kidney; Sulfanilamide; Sulfanilamides; Sulfonamides | 1952 |
The use of diamox, a carbonic anhydrase inhibitor, as an oral diuretic in patients with congestive heart failure.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Diuretics; Heart Failure; Hydro-Lyases; Sulfanilamide; Sulfanilamides; Sulfonamides | 1953 |
Use of a new oral diuretic, diamox, in congestive heart failure.
Topics: Acetazolamide; Diuretics; Heart Failure; Hydro-Lyases; Sulfanilamide; Sulfanilamides; Sulfonamides | 1953 |
[Diamox; a new non-mercurial diuretic for oral administration; clinical observations on the treatment of edema due to cardiac failure].
Topics: Acetazolamide; Administration, Oral; Diuretics; Edema; Heart Diseases; Heart Failure; Humans; Sulfanilamide; Sulfanilamides; Sulfonamides | 1953 |
Carbonic anhydrase inhibition. I. The pharmacology of diamox 2-acetylamino-1,3,4-thiadiazole-5-sulfonamide.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Diuretics; Hydro-Lyases; Sulfanilamide; Sulfanilamides; Sulfonamides; Thiadiazoles | 1954 |
[Clearance tests of kidney function in patients treated with 2-acetylamino-1,3,4-thiadiazole-5-sulfonamide (diamox)].
Topics: Acetazolamide; Diuretics; Hydro-Lyases; Kidney Function Tests; Sulfanilamide; Sulfanilamides; Sulfonamides; Thiadiazoles | 1955 |
[Variations of urinary pH of R.A. during 2-acetamido-1, 3, 4-thiadiazole-6-sulfonamide (diamox) therapy of cardiac insufficiency].
Topics: Acetazolamide; Diuretics; Heart Failure; Humans; Hydro-Lyases; Hydrogen-Ion Concentration; Sulfanilamide; Sulfanilamides; Sulfonamides | 1955 |
Renal lesions of sulfonamide type after treatment with acetazolamide (diamox).
Topics: Acetazolamide; Diuretics; Hodgkin Disease; Hydro-Lyases; Kidney; Sulfanilamide; Sulfanilamides; Sulfonamides | 1956 |
[Clinical uses of 5-acetamido-1, 3, 4-thiadiazole-2-sulfonamide (diamox)].
Topics: Acetazolamide; Diuretics; Hydro-Lyases; Sulfanilamide; Sulfanilamides; Sulfonamides | 1955 |
[The effect of 5-acetamido-1, 3, 4-thiadiazole-2-sulfonamide (diamox) on sodium balance and water excretion in cardiac edema].
Topics: Acetazolamide; Body Fluids; Diuretics; Edema, Cardiac; Heart Failure; Hydro-Lyases; Sodium; Sulfanilamide; Sulfanilamides; Sulfonamides; Water | 1955 |
[Sulfonamide therapy of non-infectious diseases].
Topics: Acetazolamide; Sulfanilamide; Sulfanilamides; Sulfonamides; Urea | 1957 |
Effect of 2-acetylamino-1,3,4-thiadiazole-5-sulfonamide (diamox) on dental caries resistance in hamsters.
Topics: Acetazolamide; Animals; Cricetinae; Dental Caries; Dental Caries Susceptibility; Sulfanilamide; Sulfanilamides; Sulfonamides; Thiadiazoles | 1957 |
The problem of bioassay and comparative potency of diuretics. II. Carbonic anhydrase inhibitors as oral diuretics.
Topics: Acetazolamide; Benzoates; Biological Assay; Carbonic Anhydrase Inhibitors; Diuretics; Humans; Sulfanilamide; Sulfanilamides; Sulfonamides | 1957 |
[Clinical experiences with mercury-free diuretics. II. Experiences with 2-acetylamino-1, 3, 4-thiadiazol-5-sulfonamide (nephramid)].
Topics: Acetazolamide; Diuretics; Edema; Humans; Mercury; Sulfanilamide; Sulfanilamides; Sulfonamides | 1957 |
Sulfa compounds in reversible inhibition of sperm metabolism by carbon dioxide.
Topics: Acetazolamide; Carbohydrate Metabolism; Carbohydrates; Carbon Dioxide; Male; Spermatozoa; Sulfanilamide; Sulfanilamides | 1957 |
[Sulfonamide inhibitors of tubular function, carbonic anhydrase inhibitors & hypoglycemics].
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Humans; Hypoglycemic Agents; Probenecid; Sulfanilamide; Sulfanilamides; Sulfonamides | 1957 |
[A new sulfonamide diuretic: chlorothiazide].
Topics: Acetazolamide; Chlorothiazide; Diuretics; Sulfanilamide; Sulfanilamides; Sulfonamides | 1958 |
[Effect of the carbonic anhydrase inhibitor 2-acetylamino-1,3,4-thiadiazole-5-sulfonamide (acetazolamide) on citric acid excretion in the urine].
Topics: Acetazolamide; Body Fluids; Carbonic Anhydrase Inhibitors; Citrates; Citric Acid; Humans; Sulfanilamide; Sulfanilamides; Sulfonamides; Thiadiazoles | 1958 |
Clinical evaluation of Su-5879 (esidrix), a new oral sulfonamide diuretic; preliminary report.
Topics: Acetazolamide; Diuretics; Hydrochlorothiazide; Sulfanilamide; Sulfanilamides; Sulfonamides | 1958 |
[Experimental-clinical studies on hydrochlorothiazide (esidrex) a new diuretically effective sulfonamide].
Topics: Acetazolamide; Biomedical Research; Diuretics; Hydrochlorothiazide; Sulfanilamide; Sulfanilamides; Sulfonamides | 1959 |
The pharmacology of hydrochlorothiazide (esidrix) a new, orally effective sulfonamide diuretic.
Topics: Acetazolamide; Diuretics; Hydrochlorothiazide; Sulfanilamide; Sulfanilamides; Sulfonamides | 1959 |
Sulfonamide compounds with high diuretic activity.
Topics: Acetazolamide; Diuretics; Electrolytes; Sulfanilamide; Sulfanilamides; Sulfonamides; Water | 1959 |
Hydrochlorothiazide; a new sulfonamide diuretic.
Topics: Acetazolamide; Diuretics; Hydrochlorothiazide; Sulfanilamide; Sulfanilamides; Sulfonamides | 1959 |
[Experimental studies on the anticonvulsive effect of acetazolamide, its derivatives and some sulfonamides].
Topics: Acetazolamide; Anticonvulsants; Sulfanilamide; Sulfanilamides; Sulfonamides | 1961 |
[Mechanism of action of some sulfonamide diuretics (acetazolamide, chlorothiazide and K-572). Experimental research on man].
Topics: Acetazolamide; Chlorothiazide; Diuretics; Humans; Male; Sulfanilamide; Sulfanilamides; Sulfonamides | 1960 |
[Acid-base equilibrium of the blood and renal function in the man subjected to a single administration of chlorothiazide or of K-572, carried out after 3 days of acetazolamide pretreatment].
Topics: Acetazolamide; Acid-Base Equilibrium; Chlorothiazide; Diuretics; Humans; Kidney; Male; Sulfanilamide; Sulfanilamides; Sulfonamides | 1959 |
[The influence of diuretics of the sulfonamide type on the urinary excretion of uric acid and on the blood level of uric acid].
Topics: Acetazolamide; Chlorothiazide; Diuretics; Humans; Sulfanilamide; Sulfanilamides; Sulfonamides; Uric Acid | 1960 |
The relation between enzyme inhibition and physiological response in the carbonic anhydrase system.
Topics: Acetazolamide; Carbonic Anhydrases; Chlorothiazide; Hydrochlorothiazide; Sulfanilamide; Sulfanilamides | 1963 |
[ON THE PAPER CHROMATOGRAPHIC DISTINCTIONS OF SULFONAMIDE DIURETICS AND SULFONAMIDES WITH OTHER AREAS OF INDICATIONS].
Topics: Acetazolamide; Antineoplastic Agents; Carbutamide; Chlorothiazide; Chromatography; Diuretics; Hydrochlorothiazide; Research; Sulfacetamide; Sulfamerazine; Sulfamethoxypyridazine; Sulfanilamide; Sulfanilamides; Sulfathiazoles; Sulfonamides; Tolbutamide | 1963 |
ZINC-FREE PLANT CARBONIC ANHYDRASE; LACK OF INHIBITION BY SULFONAMIDES.
Topics: Acetazolamide; Carbonic Anhydrases; Chemical Phenomena; Chemistry; Cobalt; Cysteine; Edetic Acid; Research; Sulfanilamide; Sulfanilamides; Sulfonamides; Zinc | 1963 |
EFFECT OF ACETAZOLAMIDE AND TRIPLE SULFONAMIDE ON CITRATE AND CALCIUM EXCRETION.
Topics: Acetazolamide; Calcium; Calcium, Dietary; Citrates; Citric Acid; Humans; Sulfacetamide; Sulfadiazine; Sulfamerazine; Sulfanilamide; Sulfanilamides; Sulfonamides; Time; Toxicology; Urinary Calculi; Urine | 1963 |
[NATRIURETIC DRUGS].
Topics: Acetazolamide; Aldosterone; Ascites; Chlorothiazide; Dexamethasone; Diabetes Insipidus; Diuresis; Diuretics; Heart Failure; Hydrochlorothiazide; Hydroflumethiazide; Hypertension; Kidney Tubules; Metyrapone; Mineralocorticoid Receptor Antagonists; Natriuresis; Pharmacology; Physiology; Spironolactone; Sulfanilamide; Sulfanilamides; Thiazines | 1963 |
TRIAMTERENE ACTIVITY INVESTIGATED BY THE STOP-FLOW TECHNIQUE AND IN VITRO STUDIES ON CARBONIC ANHYDRASE.
Topics: Acetazolamide; Ammonia; Animals; Carbonic Anhydrases; Chlorothiazide; Diuretics; In Vitro Techniques; Kidney Tubules; Pharmacology; Potassium; Research; Sulfanilamide; Sulfanilamides; Swine; Triamterene | 1963 |
COMPARISON OF THE DIURETIC ACTIVITIES OF BENZIMIDAZOLYL-TOLUENESULFANAMIDE COMPOUNDS AND ACETAZOLAMIDE.
Topics: Acetazolamide; Diuretics; Pharmacology; Rats; Research; Sulfanilamide; Sulfanilamides; Sulfonamides | 1964 |
[Clinical studies on a new sulfonamide diuretic - diacarb].
Topics: Acetazolamide; Biomedical Research; Diuretics; Sulfanilamide; Sulfanilamides; Sulfonamides | 1959 |
Purification and some properties of carbonic anhydrase from Elephas trogontherii (Steppe elephant) bone.
Topics: Acetazolamide; Animals; Bone and Bones; Carbonic Anhydrases; Elephants; Hydrogen-Ion Concentration; Isoenzymes; Sodium Azide; Sulfanilamide; Sulfanilamides; Thiocyanates | 2007 |
Characterization and inhibition studies of an α-carbonic anhydrase from the endangered sturgeon species Acipenser gueldenstaedti.
Topics: Acetazolamide; Animals; Carbonic Anhydrases; Dose-Response Relationship, Drug; Endangered Species; Enzyme Inhibitors; Erythrocytes; Fishes; Humans; Kinetics; Pesticides; Structure-Activity Relationship; Sulfanilamide; Sulfanilamides | 2011 |
Carbonic anhydrase inhibition by 1-aroyl-3-(4-aminosulfonylphenyl)thioureas.
Topics: Acetazolamide; Animals; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Cattle; Isothiocyanates; Molecular Docking Simulation; Molecular Structure; Solutions; Structure-Activity Relationship; Sulfanilamide; Sulfanilamides; Thiourea | 2014 |
The structure of a tetrameric α-carbonic anhydrase from Thermovibrio ammonificans reveals a core formed around intermolecular disulfides that contribute to its thermostability.
Topics: Acetazolamide; Bacteria; Bacterial Proteins; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Disulfides; Enzyme Stability; Kinetics; Models, Molecular; Nitrophenols; Protein Conformation; Sulfanilamide; Sulfanilamides; Temperature | 2014 |
Synthesis and biological evaluation of sulfonamide-based compounds as inhibitors of carbonic anhydrase from Vibrio cholerae.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Isoenzymes; Molecular Structure; Structure-Activity Relationship; Sulfanilamide; Sulfonamides; Vibrio cholerae | 2022 |
Sulphonamide inhibition studies of the β-carbonic anhydrase GsaCAβ present in the salmon platyhelminth parasite
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Methazolamide; Parasites; Platyhelminths; Salmon; Structure-Activity Relationship; Sulfanilamide; Sulfonamides | 2023 |