sulfamethoxazole hydroxylamine has been researched along with fluconazole in 2 studies
| Studies (sulfamethoxazole hydroxylamine) | Trials (sulfamethoxazole hydroxylamine) | Recent Studies (post-2010) (sulfamethoxazole hydroxylamine) | Studies (fluconazole) | Trials (fluconazole) | Recent Studies (post-2010) (fluconazole) |
|---|---|---|---|---|---|
| 45 | 6 | 7 | 9,343 | 721 | 3,664 |
| Protein | Taxonomy | sulfamethoxazole hydroxylamine (IC50) | fluconazole (IC50) |
|---|---|---|---|
| Lanosterol 14-alpha demethylase | Candida albicans SC5314 | 0.1296 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 9.21 | |
| Sterol 14-alpha demethylase | Trypanosoma cruzi strain CL Brener | 0.88 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kalhorn, TF; Kharasch, ED; Mitra, AK; Slattery, JT; Thummel, KE; Unadkat, JD | 1 |
| Greenspan, DL; Hooton, TM; Jacobson, M; Slattery, JT; Trapnell, CB; Unadkat, JD; Winter, HR | 1 |
2 trial(s) available for sulfamethoxazole hydroxylamine and fluconazole
| Article | Year |
|---|---|
Inhibition of sulfamethoxazole hydroxylamine formation by fluconazole in human liver microsomes and healthy volunteers.
Topics: Adult; Antifungal Agents; Cimetidine; Fluconazole; Histamine H2 Antagonists; Humans; Ketoconazole; Male; Microsomes, Liver; Reference Values; Sulfamethoxazole | 1996 |
The effect of clarithromycin, fluconazole, and rifabutin on sulfamethoxazole hydroxylamine formation in individuals with human immunodeficiency virus infection (AACTG 283).
Topics: Adult; Anti-Infective Agents; Area Under Curve; CD4 Lymphocyte Count; Clarithromycin; Drug Interactions; Female; Fluconazole; HIV Infections; HIV-1; Humans; Male; Middle Aged; Rifabutin; Sulfamethoxazole; Trimethoprim, Sulfamethoxazole Drug Combination | 2004 |