Page last updated: 2024-08-16

sulfamethoxazole and tolbutamide

sulfamethoxazole has been researched along with tolbutamide in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199011 (37.93)18.7374
1990's5 (17.24)18.2507
2000's5 (17.24)29.6817
2010's8 (27.59)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Angelini, G; Meneghini, CL1
Rahal, JJ; Simberkoff, MS1
Amla, V; Kohli, K; Sharma, JD1
Hughes, WT; Smith-McCain, BL1
Garg, SK; Ghosh, SS; Mathur, VS1
Miners, JO; Wing, LM1
Hatao, K; Kaku, K; Kaneko, T; Matsuda, M; Tsuchiya, M1
Hasselblatt, A; Poser, W; Schwabe, U1
Hossie, RD; Mattok, GL; McGilveray, IJ1
Funk, KF1
Hanano, M; Iga, T; Sawada, Y; Sugita, O; Sugiyama, Y1
Günter, S; Kunkel, A; Wätzig, H2
Back, DJ; Gill, HJ; Kitteringham, NR; Park, BK; Pirmohamed, M; Tjia, JF1
Kunkel, A; Wätzig, H2
Miller, JL; Trepanier, LA1

Other Studies

29 other study(ies) available for sulfamethoxazole and tolbutamide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
[Group sensitization by photosensitizing drugs].
    Zeitschrift fur Hautkrankheiten, 1978, May-15, Volume: 53, Issue:10

    Topics: Carbutamide; Chlorpropamide; Drug Interactions; Photosensitivity Disorders; Promethazine; Structure-Activity Relationship; Sulfamethoxazole; Sulfonamides; Tartrazine; Tolbutamide

1978
Urinary frequency in a diabetic.
    Postgraduate medicine, 1977, Volume: 62, Issue:6

    Topics: Adult; Diabetes Complications; Drug Interactions; Female; Humans; Sulfamethoxazole; Tolbutamide; Trimethoprim; Urinary Tract Infections

1977
Modification of hypoglycaemic effect of tolbutamide by co-trimoxazole.
    Journal of the Indian Medical Association, 1988, Volume: 86, Issue:3

    Topics: Animals; Blood Glucose; Drug Combinations; Drug Interactions; Female; Male; Rabbits; Sulfamethoxazole; Tolbutamide; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1988
Effects of sulfonylurea compounds on Pneumocystis carinii.
    The Journal of infectious diseases, 1986, Volume: 153, Issue:5

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Carbutamide; Chemical Phenomena; Chemistry; Drug Combinations; Immune Tolerance; Pneumonia, Pneumocystis; Rats; Sulfamethoxazole; Tolbutamide; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1986
Effect of tolbutamide treatment on the pharmacokinetics of intravenously administered sulphamethoxazole in rabbits.
    Pharmacology, 1987, Volume: 35, Issue:1

    Topics: Animals; Arylamine N-Acetyltransferase; Kinetics; Male; Protein Binding; Rabbits; Sulfamethoxazole; Tolbutamide

1987
Cotrimoxazole as an inhibitor of oxidative drug metabolism: effects of trimethoprim and sulphamethoxazole separately and combined on tolbutamide disposition.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:5

    Topics: Adult; Drug Combinations; Drug Interactions; Humans; Male; Metabolic Clearance Rate; Protein Binding; Sulfamethoxazole; Tolbutamide; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1985
Sulfonylurea stimulates liver fructose-2,6-bisphosphate formation in proportion to its hypoglycemic action.
    Diabetes research and clinical practice, 1985, Volume: 1, Issue:1

    Topics: Acetohexamide; Animals; Buformin; Chlorpropamide; Fructosediphosphates; Gliclazide; Gluconeogenesis; Glyburide; Glycolysis; Hexosediphosphates; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; Stimulation, Chemical; Sulfamethoxazole; Sulfonylurea Compounds; Tolbutamide

1985
[The blood sugar lowering effect of sulfafurazole and sulfamethoxazole in the rat].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1969, Volume: 262, Issue:1

    Topics: Animals; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Hepatectomy; Hypoglycemia; Male; Oxazoles; Rats; Sulfamethoxazole; Sulfisoxazole; Tolbutamide

1969
Technical problems of the USP-NF dissolution test.
    Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:3

    Topics: Formularies as Topic; Hydrochloric Acid; Hydrogen-Ion Concentration; Methods; Pharmacopoeias as Topic; Phosphates; Solubility; Sulfamethoxazole; Sulfisoxazole; Tablets; Time Factors; Tolbutamide; Tromethamine

1972
[Effect of protein binding on the pharmacokinetics of sulfanilamides in rats].
    Acta biologica et medica Germanica, 1971, Volume: 27, Issue:3

    Topics: Animals; Drug Antagonism; Drug Interactions; Glomerular Filtration Rate; Protein Binding; Rats; Rats, Inbred Strains; Sulfamerazine; Sulfamethoxazole; Sulfamethoxypyridazine; Sulfanilamides; Sulfisomidine; Tolbutamide

1971
Prediction of drug-drug interaction from in vitro plasma protein binding and metabolism. A study of tolbutamide-sulfonamide interaction in rats.
    Biochemical pharmacology, 1981, Dec-15, Volume: 30, Issue:24

    Topics: Animals; Blood Proteins; Drug Interactions; Half-Life; Male; Mathematics; Metabolic Clearance Rate; Rats; Rats, Inbred Strains; Sulfadimethoxine; Sulfamethoxazole; Sulfaphenazole; Sulfonamides; Tolbutamide

1981
Quantitation of acetaminophen and salicylic acid in plasma using capillary electrophoresis without sample pretreatment. Improvement of precision.
    Journal of chromatography. A, 1997, Apr-18, Volume: 768, Issue:1

    Topics: Acetaminophen; Borates; Buffers; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Reproducibility of Results; Salicylates; Salicylic Acid; Sodium Dodecyl Sulfate; Sulfamethoxazole; Tolbutamide

1997
Determination of pharmaceuticals in plasma by capillary electrophoresis without sample pretreatment reproducibility, limit of quantitation and limit of detection.
    Electrophoresis, 1997, Volume: 18, Issue:10

    Topics: Acetaminophen; Buffers; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Reproducibility of Results; Salicylates; Salicylic Acid; Sodium Dodecyl Sulfate; Sulfamethoxazole; Tolbutamide; Trimethoprim

1997
The effect of genetic polymorphisms in CYP2C9 on sulphamethoxazole N-hydroxylation.
    Pharmacogenetics, 1999, Volume: 9, Issue:1

    Topics: Aryl Hydrocarbon Hydroxylases; Base Sequence; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; DNA Primers; Humans; Hydroxylation; Kinetics; Microsomes, Liver; Mutation; Polymorphism, Genetic; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sulfamethoxazole; Tolbutamide

1999
Pharmacokinetic investigations with direct injection of plasma samples: possible savings using capillary electrophoresis (CE).
    Archiv der Pharmazie, 1999, Volume: 332, Issue:5

    Topics: Acetaminophen; Blood Proteins; Drug Monitoring; Electrophoresis, Capillary; Humans; Reproducibility of Results; Salicylic Acid; Sulfamethoxazole; Theophylline; Tolbutamide; Trimethoprim

1999
Micellar electrokinetic capillary chromatography as a powerful tool for pharmacological investigations without sample pretreatment: a precise technique providing cost advantages and limits of detection to the low nanomolar range.
    Electrophoresis, 1999, Volume: 20, Issue:12

    Topics: Acetaminophen; Chromatography, Micellar Electrokinetic Capillary; Costs and Cost Analysis; Humans; Reproducibility of Results; Salicylic Acid; Sulfamethoxazole; Theophylline; Time Factors; Tolbutamide; Trimethoprim

1999
NADH-dependent reduction of sulphamethoxazole hydroxylamine in dog and human liver microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 2000, Volume: 30, Issue:12

    Topics: Adult; Animals; Anti-Infective Agents; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Dogs; Erythromycin; Female; Humans; Inactivation, Metabolic; Kinetics; Male; Microsomes, Liver; Middle Aged; NAD; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Protein Synthesis Inhibitors; Species Specificity; Sulfamethoxazole; Tolbutamide

2000