sucrose-monolaurate has been researched along with perfluorooctane-sulfonic-acid* in 1 studies
1 other study(ies) available for sucrose-monolaurate and perfluorooctane-sulfonic-acid
Article | Year |
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Are additive effects of dietary surfactants on intestinal tight junction integrity an overlooked human health risk? - A mixture study on Caco-2 monolayers.
Surfactants may cause dysfunction of intestinal tight junctions (TJs), which is a common feature of intestinal autoimmune diseases. Effects of dietary surfactants on TJ integrity, measured as trans-epithelial resistance (TEER), were studied in Caco-2 cell monolayers. Cytotoxicity was assessed as apical LDH leakage. Monolayers were apically exposed for 60 min to the dietary surfactants solanine and chaconine (SC, potato glycoalkaloids, 0-0.25 mM), perfluorooctane sulfonic acid (PFOS, industrial contaminant, 0-0.8 mM), and sucrose monolaurate (SML, food emulsifier E 473, 0-2.0 mM) separately and as a mixture. Dose-response modelling of TEER EC Topics: Alkanesulfonic Acids; Caco-2 Cells; Fluorocarbons; Food Additives; Humans; Intestines; L-Lactate Dehydrogenase; Plant Extracts; Solanine; Solanum tuberosum; Sucrose; Surface-Active Agents; Tight Junctions | 2017 |