sucrose and sucrose octasulfate

sucrose has been researched along with sucrose octasulfate in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.90)18.7374
1990's26 (37.68)18.2507
2000's21 (30.43)29.6817
2010's15 (21.74)24.3611
2020's5 (7.25)2.80

Authors

AuthorsStudies
Ishimitsu, S; Kakehi, H; Komatsu, H; Murai, M; Okada, S1
Silvey, GL1
Boland, CR; Kraus, ER; Scheiman, JM; Yoshimura, K1
DelValle, J; Lucey, MR; Park, J; Wang, LD; Yamada, T1
Folkman, J; Scarbrough, E; Szabo, S; Vattay, P1
Ivey, KJ; Razandi, M; Romano, M1
Orlando, RC; Tobey, NA1
Orlando, RC; Powell, DW; Schreiner, VJ; Tobey, NA1
Brown, A; Szabo, S1
Hsu, BT; Rees, DC; Zhu, X1
Burke, CJ; Mach, H; Marfia, KE; Middaugh, CR; Verticelli, AM; Volkin, DB1
Beylin, I; Eberlein, G; Sluzky, V; Stratton, P; Vemuri, S; Wang, YJ1
Arakawa, T; Philo, JS; Wen, J1
Audus, KL; Shah, PK; Zheng, H1
Carter, K; Goddard, PJ; Ito, S; Khakee, R; McNeil, PL; Paimela, H; Silen, W1
Desai, UR; Linhardt, RJ; Pervin, A; Vlahov, IR1
Lerner, LE; Shen, J1
Brown, PW; Chang, J; Hwang, KK; Rao, N; Yerino, P1
Okabe, S; Takahashi, S1
Duffy, FJ; Hergrueter, CA; Maitz, PK; Pribaz, JJ1
Hileman, RE; Kagan, MZ; Linhardt, RJ; Siegel, MM; Tabei, K; Vlahov, IR1
Furukawa, O; Matsui, H; Suzuki, N1
Brown, PW; Chang, J; Geary, J; Otis, KW; Rao, N; Thompson, TN1
Kruidenier, L; Verspaget, HW1
Akita, S; Fujii, T; Ishihara, H; Rashid, MA; Razzaque, MS; Taguchi, T; Tanaka, K; Yoshimoto, H1
Iwata, M; Kitajima, A; Maekawa, K; Okada, S; Saito, H; Tanimoto, T1
Helander, HF; Jacobson, I; Poorkhalkali, N1
Bottaro, DP; Byrd, RA; Casas-Finet, JR; Heath Coats, R; Kaufman, JD; Rubin, JS; Stahl, SJ; Wingfield, PT; Zhou, H1
Forsten, KE; Nugent, MA; Robinson, RM; Wang, N1
Forsten, KE; Nugent, MA1
Bjordal, K; Evensen, JF; Jacobsen, AB; Løkkevik, E; Tausjø, JE1
Arunkumar, AI; Chang, GG; Chen, HC; Chi, YH; Chiu, IM; Kathir, KM; Kumar, TK; Leena, PS; Srisailam, S; Wang, HM; Wu, CH; Wu, RT; Yu, C1
Hiebert, LM; Hileman, RE; Linhardt, RJ; Ping, T; Polat, T; Wice, SM1
Eliseenkova, AV; Green, D; Gritli-Linde, A; Linhardt, RJ; Mohammadi, M; Pinnell, J; Plotnikov, AN; Polat, T; Yeh, BK1
Birdsall, B; Chai, W; Frenkiel, TA; Kogelberg, H; Muskett, FW1
Hyvönen, M; Innis, CA1
Gunay, NS; Ishizuka, I; Linhardt, RJ; Tadano-Aritomi, K; Toida, T1
Chi, YH; Chiu, IM; Hung, KW; Kumar, TK; Yu, C1
Berezin, V; Bock, E; Kiselyov, V; Kulahin, N; Poulsen, FM; Rudenko, O1
Chen, MC; Chiu, IM; Hung, KW; Ji, HH; Kathir, KM; Kumar, TK; Lin, FP; Ni, F; Xu, P; Yang, CC; Yu, C1
Leary, JA; Saad, OM; Sweeney, MD; Yu, Y1
Joshi, SB; Kamerzell, TJ; Li, M; McClean, D; Middaugh, CR; Papac, D; Peplinskie, L; Toney, K1
Clark, SJ; Day, AJ; Johnson, S; Lea, SM; Prosser, BE; Roversi, P; Sim, RB; Tarelli, E1
Barlow, PN; Blaum, BS; Clark, SJ; Day, AJ; Herbert, AP; Johnson, S; Jowitt, TA; Lea, SM; Prosser, BE; Roversi, P; Sim, RB; Tarelli, E; Tyrrell, J; Uhrín, D1
Barnes, C; Chu, CL; Fannon, M; Forsten-Williams, K; Goerges-Wildt, AL; Gregory, KJ; Kaipainen, A; Lapp, C; Nugent, MA; Panigrahy, D; Shing, Y1
Berezin, V; Bock, E; Gajhede, M; Kastrup, JS; Kiselyov, V; Kochoyan, A; Kristensen, O; Kulahin, N1
Helbert, W; Jacquinet, JC; Jouanneau, D; Ohara, K; Smietana, M; Vasseur, JJ1
Bespalov, MM; Goldman, A; Jurvansuu, JM; Leppänen, VM; Parkash, V; Runeberg-Roos, P; Saarma, M; Sidorova, YA; Virtanen, H1
Amster, IJ; Laremore, TN; Leach Ii, FE; Linhardt, RJ; Wolff, JJ1
Demeler, B; Folta-Stogniew, E; Ha, Y; Hoopes, JT; Li, C; Liu, X; Xu, X1
Gailani, D; Habib, SY; Kravtsov, DV; Matafonov, A; Sarilla, S; Verhamme, IM1
Cho, KJ; Kim, KH; Kim, TG; Lee, JH; Park, BS; Park, Y; Yang, IS1
Boothello, RS; Desai, BJ; Desai, UR; Mehta, AY; Scarsdale, JN; Wright, HT1
Barnard, TJ; Buchanan, SK; Felek, S; Hinnebusch, BJ; Krukonis, ES; Lukacik, P; Noinaj, N; Tsang, TM; Yamashita, S1
Bach, E; Buczek-Thomas, JA; Chu, CL; Fannon, M; Forsten-Williams, K; Goerges-Wildt, AL; Nugent, MA; Parekh, PP; Zhao, B1
Calderini, G; Comelli, MC; Marianelli, C; Petrucci, P1
Chang, LD; Kapanadze, T; Ke, Y; Li, SL1
Alfayate-García, JM; Bohbot, S; Edmonds, M; Kerihuel, JC; Lázaro-Martínez, JL; Lobmann, R; Martini, J; Petit, JM; Piaggesi, A; Rayman, G; Sauvadet, A; Uccioli, L1
Chen, K; Deelman, TE; Karp, JM; Lee, Y; Lin, DSY; Tavakkoli, A1
Fu, J; Guo, M; Liu, D; Liu, H; Sun, B; Wei, W; Yang, W; Yang, Z1
Chi, D; Liu, J; Pan, S; Wang, D; Wang, X; Wang, Y; Zhao, L1
Adachi, K; Hayakawa, T; Hirayama, Y; Kawasaki, S; Kon, R; Suematsu, M; Sugiura, Y; Sugiyama, E; Tsutsui, T1
Apelqvist, J; Bohbot, S; Edmonds, M; Hartemann, A; Kerihuel, JC; Lázaro-Martínez, JL; Lobmann, R; Martini, J; Piaggesi, A; Rayman, G; Van Acker, K1
Augustin, M; Fietz, C; Lawall, H; Lobmann, R; Potempa, C; Rychlik, RP; Thiem, H; Tigges, W1
Augustin, M; Dietlein, M; Dissemond, J; Keuthage, W; Läuchli, S; Lobmann, R; Münter, KC; Strohal, R; Stücker, M; Traber, J; Vanscheidt, W1
Grünerbel, A; Lawall, H; Lobmann, R; Lüdemann, C; Morbach, S; Rychlik, RP; Tigges, W; Völkel, L1
Bassetto, F; Scarpa, C; Vindigni, V1
Gallardo, RC; Pozo, AP; Sagüez, FS1
Al Sayah, F; Jin, X; Johnson, JA; Ohinmaa, A; Paulden, M; Wen, J1

Reviews

3 review(s) available for sucrose and sucrose octasulfate

ArticleYear
Antioxidants and mucosa protectives: realistic therapeutic options in inflammatory bowel disease?
    Mediators of inflammation, 1998, Volume: 7, Issue:3

    Topics: Antioxidants; Fatty Acids; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Reactive Oxygen Species; Sucrose

1998
[Sucrose octasulfate-evidence in the treatment of chronic wounds].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2020, Volume: 71, Issue:10

    Topics: Anti-Ulcer Agents; Humans; Sucrose; Varicose Ulcer; Wound Healing

2020
Uso de apósitos con TLC-NOSF en el manejo de la úlcera de pie diabético, basado en la revisión de la evidencia y la práctica clínica.
    Journal of wound care, 2020, Nov-01, Volume: 29, Issue:LatAm sup

    Topics: Bandages; Colloids; Diabetic Foot; Humans; Prevalence; Sucrose; Technology; Treatment Outcome; Wound Healing

2020

Trials

5 trial(s) available for sucrose and sucrose octasulfate

ArticleYear
Effects of Na-sucrose octasulfate on skin and mucosa reactions during radiotherapy of head and neck cancers--a randomized prospective study.
    Acta oncologica (Stockholm, Sweden), 2001, Volume: 40, Issue:6

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-Blind Method; Female; Gels; Head and Neck Neoplasms; Humans; Male; Middle Aged; Prospective Studies; Radiotherapy; Skin Diseases; Stomatitis; Sucrose; Treatment Outcome

2001
Sucrose octasulfate dressing versus control dressing in patients with neuroischaemic diabetic foot ulcers (Explorer): an international, multicentre, double-blind, randomised, controlled trial.
    The lancet. Diabetes & endocrinology, 2018, Volume: 6, Issue:3

    Topics: Aged; Anti-Ulcer Agents; Bandages; Diabetic Foot; Diabetic Neuropathies; Double-Blind Method; Female; Humans; International Agencies; Ischemia; Male; Prognosis; Sucrose

2018
Optimal wound closure of diabetic foot ulcers with early initiation of TLC-NOSF treatment: post-hoc analysis of Explorer.
    Journal of wound care, 2019, Jun-02, Volume: 28, Issue:6

    Topics: Aged; Bandages; Colloids; Diabetic Foot; Double-Blind Method; Female; Humans; Male; Middle Aged; Sucrose; Time Factors; Treatment Outcome; Wound Healing

2019
Cost-effectiveness of TLC-sucrose octasulfate versus control dressings in the treatment of diabetic foot ulcers.
    Journal of wound care, 2019, Dec-02, Volume: 28, Issue:12

    Topics: Anti-Ulcer Agents; Bandages, Hydrocolloid; Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Diabetic Foot; Double-Blind Method; Europe; Female; Humans; Male; Middle Aged; Sucrose; Treatment Outcome

2019
Impact of wound duration on diabetic foot ulcer healing: evaluation of a new sucrose octasulfate wound dressing.
    Journal of wound care, 2020, Oct-02, Volume: 29, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Bandages; Diabetes Complications; Diabetes Mellitus; Diabetic Foot; Double-Blind Method; Female; Germany; Humans; Male; Middle Aged; Sucrose; Time Factors; Treatment Outcome; Wound Healing

2020

Other Studies

61 other study(ies) available for sucrose and sucrose octasulfate

ArticleYear
[Potassium Sucrose Octa Sulfate Reference Standard (Control 901) of National Institute of Hygienic Sciences].
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1991, Issue:109

    Topics: Chromatography, High Pressure Liquid; Government Agencies; Hygiene; Japan; Pharmacopoeias as Topic; Spectrophotometry, Infrared; Sucrose

1991
Two-dimensional and deuterium-induced, differential-isotope-shift nuclear magnetic resonance characterization of potassium sucrose octasulfate and sucralfate.
    Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:5

    Topics: Carbohydrate Sequence; Carbon Isotopes; Deuterium; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Spectrum Analysis; Sucralfate; Sucrose; Sulfur

1992
Effect of sucralfate on components of mucosal barrier produced by cultured canine epithelial cells in vitro.
    Digestive diseases and sciences, 1992, Volume: 37, Issue:12

    Topics: Animals; Cells, Cultured; Dinoprostone; Dogs; Gastric Mucosa; Glycoproteins; Indomethacin; Mucins; Phospholipids; Sucralfate; Sucrose

1992
Sucrose octasulfate stimulates gastric somatostatin release.
    The American journal of medicine, 1991, Aug-08, Volume: 91, Issue:2A

    Topics: Aminopyrine; Animals; Bucladesine; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Gastric Fundus; Gastrins; Isoproterenol; Male; Octreotide; Parietal Cells, Gastric; Peptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Sucrose; Tetradecanoylphorbol Acetate

1991
Role of vascular factors, including angiogenesis, in the mechanisms of action of sucralfate.
    The American journal of medicine, 1991, Aug-08, Volume: 91, Issue:2A

    Topics: Animals; Drug Evaluation, Preclinical; Drug Implants; Female; Gastric Mucosa; Granulation Tissue; Neovascularization, Pathologic; Rats; Rats, Inbred Strains; Sucralfate; Sucrose; Wound Healing

1991
Effect of sucralfate and its components on taurocholate-induced damage to rat gastric mucosal cells in tissue culture.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:4

    Topics: Aluminum Hydroxide; Animals; Cells, Cultured; Chromium Radioisotopes; Culture Techniques; Drug Interactions; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Iodoacetamide; Prostaglandins; Radioimmunoassay; Rats; Rats, Inbred Strains; Sucralfate; Sucrose; Sulfhydryl Compounds; Taurocholic Acid

1990
Why does sucralfate improve healing in reflux esophagitis? The role of sucrose octasulfate.
    Scandinavian journal of gastroenterology. Supplement, 1990, Volume: 173

    Topics: Antacids; Drug Combinations; Drug Evaluation, Preclinical; Esophagitis, Peptic; Esophagus; Gastric Acid; Gastric Mucosa; Humans; In Vitro Techniques; Sucralfate; Sucrose; Wound Healing

1990
Cytoprotection by sucralfate: role of sulfate ions.
    Scandinavian journal of gastroenterology. Supplement, 1987, Volume: 140

    Topics: Animals; Esophagitis, Peptic; Esophagus; Rabbits; Structure-Activity Relationship; Sucralfate; Sucrose; Sulfates

1987
Prevention of ethanol-induced vascular injury and gastric mucosal lesions by sucralfate and its components: possible role of endogenous sulfhydryls.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1987, Volume: 185, Issue:4

    Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Ethanol; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Rats; Rats, Inbred Strains; Stomach Diseases; Sucralfate; Sucrose; Sulfates

1987
Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factor.
    Structure (London, England : 1993), 1993, Sep-15, Volume: 1, Issue:1

    Topics: Amino Acid Sequence; Anti-Ulcer Agents; Binding Sites; Computer Graphics; Crystallography, X-Ray; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Sucrose

1993
Sucralfate and soluble sucrose octasulfate bind and stabilize acidic fibroblast growth factor.
    Biochimica et biophysica acta, 1993, Nov-10, Volume: 1203, Issue:1

    Topics: Binding, Competitive; Calorimetry, Differential Scanning; Circular Dichroism; Fibroblast Growth Factor 1; Heparin; Hot Temperature; Hydrogen-Ion Concentration; Recombinant Proteins; Spectrometry, Fluorescence; Sucralfate; Sucrose; Suramin; Urea

1993
The stability of bFGF against thermal denaturation.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:6

    Topics: Buffers; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Drug Stability; Electrophoresis, Polyacrylamide Gel; Fibroblast Growth Factor 2; Heparin; Hot Temperature; Humans; Hydrogen-Ion Concentration; Inositol; Protein Denaturation; Recombinant Proteins; Sucrose; Technology, Pharmaceutical

1994
Densimetric determination of equilibrium binding of sucrose octasulfate with basic fibroblast growth factor.
    Journal of protein chemistry, 1993, Volume: 12, Issue:6

    Topics: Amino Acid Sequence; Fibroblast Growth Factor 2; Hot Temperature; Kinetics; Mutagenesis, Site-Directed; Protein Binding; Protein Denaturation; Recombinant Proteins; Spectrophotometry; Sucrose; Thermodynamics

1993
Primary culture of rat gastric epithelial cells as an in vitro model to evaluate antiulcer agents.
    Pharmaceutical research, 1994, Volume: 11, Issue:1

    Topics: Acids; Aluminum Hydroxide; Animals; Anti-Ulcer Agents; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Coloring Agents; Drug Evaluation, Preclinical; Epithelial Cells; Gastric Mucosa; Indomethacin; Microscopy, Phase-Contrast; Neutral Red; Rats; Rats, Sprague-Dawley; Sucralfate; Sucrose; Tetrazolium Salts; Thiazoles

1994
Restitution of frog gastric mucosa in vitro: effect of basic fibroblast growth factor.
    Gastroenterology, 1993, Volume: 104, Issue:5

    Topics: Animals; Fibroblast Growth Factor 2; Gastric Mucosa; Immunohistochemistry; In Vitro Techniques; Protamines; Rana catesbeiana; Sucrose; Suramin; Wound Healing

1993
Conformational analysis of sucrose octasulfate by high resolution nuclear magnetic resonance spectroscopy.
    Carbohydrate research, 1995, Oct-02, Volume: 275, Issue:2

    Topics: Carbohydrate Conformation; Carbohydrate Sequence; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Sucrose

1995
A comparison of the conformation of sucrose octasulfate, free and bound to acidic fibroblast growth factor.
    Carbohydrate research, 1995, Aug-25, Volume: 273, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Carbohydrate Conformation; Carbohydrate Sequence; Crystallography, X-Ray; Fibroblast Growth Factor 1; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Protein Binding; Sucrose

1995
Comparative absorption of bismuth in Sprague-Dawley rats following oral administration of preparations containing bismuth sucrose octasulfate, bismuth subsalicylate, and bismuth subcitrate.
    Biopharmaceutics & drug disposition, 1997, Volume: 18, Issue:1

    Topics: Administration, Oral; Animals; Antacids; Area Under Curve; Bismuth; Intestinal Absorption; Male; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Salicylates; Spectrophotometry, Atomic; Sucrose; Tissue Distribution

1997
Effects of sucralfate and its components on indomethacin-induced damage to cultured rabbit gastric mucosal cells.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1996, Volume: 47, Issue:4

    Topics: Aluminum Hydroxide; Animals; Cell Survival; Cells, Cultured; Gastric Mucosa; Gastrointestinal Agents; Indomethacin; Male; Rabbits; Sucralfate; Sucrose

1996
Maximizing flap survival in a prefabrication model using exogenous and endogenous bFGF: a new approach.
    Microsurgery, 1996, Volume: 17, Issue:4

    Topics: Animals; Ear, External; Female; Fibroblast Growth Factor 2; Graft Survival; Rabbits; Sucrose; Surgical Flaps

1996
Polysulfated carbohydrates analyzed as ion-paired complexes with basic peptides and proteins using electrospray negative ionization mass spectrometry.
    Journal of mass spectrometry : JMS, 1997, Volume: 32, Issue:7

    Topics: Carbohydrates; Cyclodextrins; Mass Spectrometry; Molecular Weight; Oligosaccharides; Peptides; Proteins; Sucrose; Sulfates

1997
Effects of sucralfate and its components on acid- and pepsin-induced damage to rat gastric epithelial cells.
    Japanese journal of pharmacology, 1997, Volume: 75, Issue:1

    Topics: Acids; Aluminum Hydroxide; Animals; Anti-Ulcer Agents; Cells, Cultured; Epithelial Cells; Gastric Mucosa; Hydrogen-Ion Concentration; Pepsin A; Pepstatins; Protease Inhibitors; Rats; Sucralfate; Sucrose

1997
Mass balance of 14C-bismuth sucrose octasulfate in Sprague-Dawley rats: evidence for dissociation of bismuth from sucrose octasulfate.
    Biopharmaceutics & drug disposition, 1997, Volume: 18, Issue:9

    Topics: Absorption; Administration, Oral; Animals; Anti-Ulcer Agents; Area Under Curve; Bile; Bismuth; Brain; Carbon Radioisotopes; Feces; Kidney; Liver; Lung; Male; Rats; Rats, Sprague-Dawley; Sucrose; Tissue Distribution

1997
Coadministration of basic fibroblast growth factor and sucrose octasulfate (sucralfate) facilitates the rat dorsal flap survival and viability.
    Plastic and reconstructive surgery, 1999, Volume: 103, Issue:3

    Topics: Actins; Angiography; Animals; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Graft Survival; Immunohistochemistry; Male; Microradiography; Polymerase Chain Reaction; Rats; Rats, Wistar; Sucralfate; Sucrose; Surgical Flaps

1999
[Potassium Sucrose Octa Sulfate Reference Standard (Control 961) of National Institute of Health Sciences].
    Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences, 1998, Issue:116

    Topics: Government Agencies; Japan; Reference Standards; Sucrose

1998
Lectin histochemistry of the esophagus in several mammalian species.
    Anatomy and embryology, 1999, Volume: 200, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Cats; Dogs; Esophagus; Ferrets; Fluorescent Antibody Technique; Glycoconjugates; Humans; Hydrochloric Acid; Lectins; Pepsin A; Rabbits; Sucrose; Swine

1999
Identification and dynamics of a heparin-binding site in hepatocyte growth factor.
    Biochemistry, 1999, Nov-09, Volume: 38, Issue:45

    Topics: Animals; Binding Sites; Dimerization; Heparin; Hepatocyte Growth Factor; Kinetics; Models, Molecular; Molecular Weight; Peptide Fragments; Sucrose; Swine

1999
A simple assay for evaluating inhibitors of proteoglycan-ligand binding.
    Annals of biomedical engineering, 2000, Volume: 28, Issue:1

    Topics: Animals; Biomedical Engineering; Cattle; Cell-Free System; Cells, Cultured; Culture Media, Conditioned; Drug Evaluation, Preclinical; Endothelium, Vascular; Fibroblast Growth Factor 2; Heparan Sulfate Proteoglycans; Heparin; Heparitin Sulfate; Humans; In Vitro Techniques; Insulin-Like Growth Factor I; Kinetics; Ligands; Protamines; Protein Binding; Proteoglycans; Recombinant Proteins; Sucrose

2000
Binding constant measurements for inhibitors of growth factor binding to heparan sulfate proteoglycans.
    Methods in molecular biology (Clifton, N.J.), 2001, Volume: 171

    Topics: Animals; Cattle; Fibroblast Growth Factor 2; Growth Substances; Heparan Sulfate Proteoglycans; Humans; In Vitro Techniques; Kinetics; Ligands; Protamines; Protein Binding; Recombinant Proteins; Software; Sucrose

2001
Oligomerization of acidic fibroblast growth factor is not a prerequisite for its cell proliferation activity.
    Protein science : a publication of the Protein Society, 2002, Volume: 11, Issue:5

    Topics: Animals; Binding Sites; Chromatography; Fibroblast Growth Factor 1; Mitogens; Notophthalmus viridescens; Sucrose

2002
Tissue distribution of [14C]sucrose octasulfate following oral administration to rats.
    Pharmaceutical research, 2002, Volume: 19, Issue:6

    Topics: Administration, Oral; Animals; Carbon Radioisotopes; Male; Rats; Rats, Wistar; Sucrose; Tissue Distribution

2002
Structural basis for activation of fibroblast growth factor signaling by sucrose octasulfate.
    Molecular and cellular biology, 2002, Volume: 22, Issue:20

    Topics: Animals; Crystallography, X-Ray; Dimerization; Fibroblast Growth Factor 2; Heparin; Mice; Models, Molecular; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Signal Transduction; Sucrose

2002
Binding of sucrose octasulphate to the C-type lectin-like domain of the recombinant natural killer cell receptor NKR-P1A observed by NMR spectroscopy.
    Chembiochem : a European journal of chemical biology, 2002, Nov-04, Volume: 3, Issue:11

    Topics: Antigens, Surface; Humans; Killer Cells, Natural; Lectins, C-Type; Ligands; Magnetic Resonance Spectroscopy; NK Cell Lectin-Like Receptor Subfamily B; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sucrose

2002
Crystal structures of the heparan sulfate-binding domain of follistatin. Insights into ligand binding.
    The Journal of biological chemistry, 2003, Oct-10, Volume: 278, Issue:41

    Topics: Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Follistatin; Heparitin Sulfate; In Vitro Techniques; Inositol; Ligands; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Static Electricity; Sucrose

2003
Evaluation of counterions for electrospray ionization mass spectral analysis of a highly sulfated carbohydrate, sucrose octasulfate.
    Analytical chemistry, 2003, Jul-01, Volume: 75, Issue:13

    Topics: Cations; Quaternary Ammonium Compounds; Spectrometry, Mass, Electrospray Ionization; Sucrose

2003
Molecular cloning, overexpression, and characterization of the ligand-binding D2 domain of fibroblast growth factor receptor.
    Biochemical and biophysical research communications, 2004, Apr-23, Volume: 317, Issue:1

    Topics: Amino Acid Sequence; Calorimetry; Circular Dichroism; Cloning, Molecular; Escherichia coli; Fibroblast Growth Factors; Humans; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Denaturation; Protein Renaturation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor; Recombinant Proteins; Sucrose; Urea

2004
Modulation of the homophilic interaction between the first and second Ig modules of neural cell adhesion molecule by heparin.
    Journal of neurochemistry, 2005, Volume: 95, Issue:1

    Topics: Animals; Binding Sites; Cell Line; Cerebellum; Chondroitin Sulfates; Coculture Techniques; Fibroblasts; Heparin; Heparitin Sulfate; Immunoglobulins; Magnetic Resonance Spectroscopy; Mice; Neural Cell Adhesion Molecules; Neurites; Neurons; Peptide Fragments; Protein Structure, Tertiary; Sucrose; Surface Plasmon Resonance

2005
Solution structure of the ligand binding domain of the fibroblast growth factor receptor: role of heparin in the activation of the receptor.
    Biochemistry, 2005, Dec-06, Volume: 44, Issue:48

    Topics: Binding Sites; Electron Spin Resonance Spectroscopy; Heparin; Humans; Ligands; Models, Molecular; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Fibroblast Growth Factor; Sucrose

2005
Potential inhibitors of chemokine function: analysis of noncovalent complexes of CC chemokine and small polyanionic molecules by ESI FT-ICR mass spectrometry.
    Journal of the American Society for Mass Spectrometry, 2006, Volume: 17, Issue:4

    Topics: Calorimetry; Carbohydrate Sequence; Chemokine CCL2; Chemokine CCL7; Chemokines, CC; Cyclodextrins; Fondaparinux; Fourier Analysis; Humans; In Vitro Techniques; Kinetics; Macromolecular Substances; Molecular Sequence Data; Molecular Structure; Monocyte Chemoattractant Proteins; Polyelectrolytes; Polymers; Polysaccharides; Spectrometry, Mass, Electrospray Ionization; Sucrose

2006
Parathyroid hormone is a heparin/polyanion binding protein: binding energetics and structure modification.
    Protein science : a publication of the Protein Society, 2007, Volume: 16, Issue:6

    Topics: Calorimetry; Dextran Sulfate; Heparin; Parathyroid Hormone; Phytic Acid; Polyelectrolytes; Polymers; Protein Binding; Protein Structure, Tertiary; Spectrometry, Fluorescence; Sucrose

2007
Expression, purification, cocrystallization and preliminary crystallographic analysis of sucrose octasulfate/human complement regulator factor H SCRs 6-8.
    Acta crystallographica. Section F, Structural biology and crystallization communications, 2007, Jun-01, Volume: 63, Issue:Pt 6

    Topics: Complement Factor H; Crystallization; Crystallography, X-Ray; Gene Expression Regulation; Humans; Recombinant Proteins; Sucrose

2007
Structural basis for complement factor H linked age-related macular degeneration.
    The Journal of experimental medicine, 2007, Oct-01, Volume: 204, Issue:10

    Topics: Aging; Binding Sites; Complement Factor H; Crystallography, X-Ray; Gene Products, gag; Ligands; Models, Molecular; Mutation; Polysaccharides; Protein Structure, Quaternary; Protein Structure, Tertiary; Sucrose; Surface Properties

2007
Sucrose octasulfate regulates fibroblast growth factor-2 binding, transport, and activity: potential for regulation of tumor growth.
    Journal of cellular physiology, 2008, Volume: 215, Issue:2

    Topics: Animals; Biological Transport; Blood Coagulation; Capillaries; Carcinoma, Lewis Lung; Cattle; Cell Division; Cell Proliferation; Cells, Cultured; Descemet Membrane; Dose-Response Relationship, Drug; Endothelial Cells; Fibroblast Growth Factor 2; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Sucrose

2008
Dimerization effect of sucrose octasulfate on rat FGF1.
    Acta crystallographica. Section F, Structural biology and crystallization communications, 2008, Jun-01, Volume: 64, Issue:Pt 6

    Topics: Animals; Anti-Ulcer Agents; Binding Sites; Chromatography, Gel; Crystallography, X-Ray; Dimerization; DNA, Complementary; Escherichia coli; Fibroblast Growth Factor 1; Hydrogen Bonding; Models, Molecular; Molecular Weight; Protein Binding; Protein Structure, Tertiary; Rats; Sucrose

2008
Matrix-assisted laser desorption/ionization mass spectrometric analysis of polysulfated-derived oligosaccharides using pyrenemethylguanidine.
    Journal of the American Society for Mass Spectrometry, 2009, Volume: 20, Issue:1

    Topics: Carrageenan; Chondroitin Sulfates; Eukaryota; Methylguanidine; Oligosaccharides; Pyrenes; Software; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sucrose; Sulfates

2009
The structure of the glial cell line-derived neurotrophic factor-coreceptor complex: insights into RET signaling and heparin binding.
    The Journal of biological chemistry, 2008, Dec-12, Volume: 283, Issue:50

    Topics: Animals; Binding Sites; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Heparin; Humans; Ligands; MAP Kinase Signaling System; Molecular Conformation; Protein Binding; Protein Structure, Quaternary; Proto-Oncogene Proteins c-ret; Rats; Sucrose; Thrombin

2008
Electron capture dissociation, electron detachment dissociation and infrared multiphoton dissociation of sucrose octasulfate.
    European journal of mass spectrometry (Chichester, England), 2009, Volume: 15, Issue:2

    Topics: Electrons; Fourier Analysis; Ions; Spectrometry, Mass, Electrospray Ionization; Sucrose; Tandem Mass Spectrometry

2009
Structural characterization of the E2 domain of APL-1, a Caenorhabditis elegans homolog of human amyloid precursor protein, and its heparin binding site.
    The Journal of biological chemistry, 2010, Jan-15, Volume: 285, Issue:3

    Topics: Amino Acid Sequence; Amyloid beta-Protein Precursor; Animals; Binding Sites; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Crystallography, X-Ray; Heparin; Humans; Hydrogen-Ion Concentration; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Stability; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Solutions; Sucrose

2010
Sucrose octasulfate selectively accelerates thrombin inactivation by heparin cofactor II.
    The Journal of biological chemistry, 2010, Mar-12, Volume: 285, Issue:11

    Topics: Allosteric Regulation; Anticoagulants; Binding, Competitive; Blood Coagulation; Enzyme Activation; Enzyme Precursors; Heparin Cofactor II; Hirudins; Humans; Kinetics; Models, Chemical; Plasma; Protease Inhibitors; Prothrombin; Spectrometry, Fluorescence; Sucrose; Thrombin

2010
Crystal structures of aprotinin and its complex with sucrose octasulfate reveal multiple modes of interactions with implications for heparin binding.
    Biochemical and biophysical research communications, 2010, Jul-02, Volume: 397, Issue:3

    Topics: Animals; Aprotinin; Cattle; Crystallization; Crystallography, X-Ray; Heparin; Protein Binding; Protein Conformation; Protein Multimerization; Protein Stability; Sucrose

2010
Interaction of thrombin with sucrose octasulfate.
    Biochemistry, 2011, Aug-16, Volume: 50, Issue:32

    Topics: Animals; Carbohydrate Sequence; Cattle; Crystallography, X-Ray; Heparin, Low-Molecular-Weight; Humans; Models, Molecular; Molecular Sequence Data; Protein Binding; Spectrometry, Fluorescence; Sucrose; Thermodynamics; Thrombin; Ultracentrifugation

2011
Structural insights into Ail-mediated adhesion in Yersinia pestis.
    Structure (London, England : 1993), 2011, Nov-09, Volume: 19, Issue:11

    Topics: Amino Acid Sequence; Bacterial Adhesion; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cell Line; Crystallography, X-Ray; Extracellular Matrix; Extracellular Matrix Proteins; Host-Pathogen Interactions; Humans; Laminin; Membrane Proteins; Molecular Chaperones; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Sequence Alignment; Sucrose; Surface Properties; Virulence Factors; Yersinia pestis

2011
Facilitated diffusion of VEGF165 through descemet's membrane with sucrose octasulfate.
    Journal of cellular physiology, 2012, Volume: 227, Issue:11

    Topics: Animals; Cattle; Cells, Cultured; Descemet Membrane; Diffusion Chambers, Culture; Extracellular Matrix; Facilitated Diffusion; Fibronectins; Humans; Muscle, Smooth, Vascular; Protein Binding; Sucrose; Vascular Endothelial Growth Factor A

2012
Silver sucrose octasulfate (IASOS™) as a valid active ingredient into a novel vaginal gel against human vaginal pathogens: in vitro antimicrobial activity assessment.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Anti-Infective Agents; Candida albicans; Enterobacter aerogenes; Escherichia coli; Female; Gardnerella vaginalis; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Silver; Staphylococcus aureus; Streptococcus agalactiae; Sucrose; Vagina; Vaginal Creams, Foams, and Jellies

2014
A novel ultra performance liquid chromatography-tandem mass spectrometry method for the determination of sucrose octasulfate in dog plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015, Jan-26, Volume: 978-979

    Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Drug Stability; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Sucrose; Tandem Mass Spectrometry

2015
Therapeutic luminal coating of the intestine.
    Nature materials, 2018, Volume: 17, Issue:9

    Topics: Aluminum; Animals; Hydrogen-Ion Concentration; Intestinal Mucosa; Organometallic Compounds; Porosity; Rats; Rats, Sprague-Dawley; Sucrose; Tomography, X-Ray Computed

2018
The influence of trapping agents on the antitumor efficacy of irinotecan liposomes: head-to-head comparison of ammonium sulfate, sulfobutylether-β-cyclodextrin and sucrose octasulfate.
    Biomaterials science, 2018, Dec-18, Volume: 7, Issue:1

    Topics: Ammonium Sulfate; Animals; Antineoplastic Agents; beta-Cyclodextrins; Colonic Neoplasms; Delayed-Action Preparations; Drug Liberation; HT29 Cells; Humans; Irinotecan; Liposomes; Male; Mice, Nude; Rats, Sprague-Dawley; Sucrose; Topoisomerase I Inhibitors

2018
Effective co-encapsulation of doxorubicin and irinotecan for synergistic therapy using liposomes prepared with triethylammonium sucrose octasulfate as drug trapping agent.
    International journal of pharmaceutics, 2019, Feb-25, Volume: 557

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Doxorubicin; Drug Liberation; Drug Synergism; Erythrocytes; Female; Humans; Irinotecan; Liposomes; Methylamines; Mice, Inbred BALB C; Neoplasms; Rabbits; Rats, Sprague-Dawley; Sucrose; Tissue Distribution; Tumor Burden

2019
A thin layer of sucrose octasulfate protects the oesophageal mucosal epithelium in reflux oesophagitis.
    Scientific reports, 2019, 03-05, Volume: 9, Issue:1

    Topics: Animals; Esophageal Mucosa; Esophagitis, Peptic; Gastric Juice; Male; Peptic Ulcer; Rats; Rats, Sprague-Dawley; Sucrose

2019
The TLC-NOSF (Technology Lipido-Colloid Plus Nano-Oligo Saccharide Factor) protease inhibitor for the treatment of ulceration in rheumatic disease A case report.
    Annali italiani di chirurgia, 2020, Oct-14, Volume: 9

    Topics: Adult; Bandages, Hydrocolloid; Chronic Disease; Colloids; Female; Humans; Leg Ulcer; Lipids; Lupus Erythematosus, Systemic; Protease Inhibitors; Sucrose; Vasculitis; Wound Healing

2020
Economic Evaluation of Sucrose Octasulfate Dressing for Treatment of Diabetic Foot Ulcers in Patients with Type 2 Diabetes.
    Canadian journal of diabetes, 2022, Volume: 46, Issue:2

    Topics: Bandages; Canada; Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Diabetic Foot; Humans; Sucrose

2022