sucrose and irinotecan

sucrose has been researched along with irinotecan in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Butler, RN; Davidson, GP; Howarth, GS; Tooley, KL1
Chen, LT; Dito, E; Ko, AH; Lin, YL; Ong, A; Shan, YS; Su, WC; Tempero, MA; Wang, YW; Yeh, CG1
Calderon, RI; Cruz, RE; Drummond, DC; Fitzgerald, JB; Hall, CP; Hindle, A; Kang, MH; Ko, W; Lee, JS; Makena, MR; Paz, N; Reynolds, CP; Song, MM; Triche, TJ; Wang, J1
André, T; Arbaud, C; Bachet, JB; Bennamoun, M; Bonnetain, F; Brusquant, D; Chibaudel, B; de Gramont, A; Dupuis, O; Garcia, ML; Hammel, P; Khalil, A; Larsen, AK; Louvet, C; Maindrault-Gœbel, F; Tournigand, C; Wang, YW; Yeh, CG1
Fu, J; Guo, M; Liu, D; Liu, H; Sun, B; Wei, W; Yang, W; Yang, Z1
Chi, D; Liu, J; Pan, S; Wang, D; Wang, X; Wang, Y; Zhao, L1
Huh, YC; Hur, M; Kim, JH; Kim, YH; Koo, SC; Lee, YJ; Moon, YH; Park, WT; Vinh, LB; Yang, SY1

Trials

2 trial(s) available for sucrose and irinotecan

ArticleYear
A multinational phase 2 study of nanoliposomal irinotecan sucrosofate (PEP02, MM-398) for patients with gemcitabine-refractory metastatic pancreatic cancer.
    British journal of cancer, 2013, Aug-20, Volume: 109, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Disease-Free Survival; Drug Combinations; Female; Humans; Irinotecan; Liposomes; Male; Middle Aged; Pancreatic Neoplasms; Salvage Therapy; Sucrose; Treatment Outcome

2013
PEPCOL: a GERCOR randomized phase II study of nanoliposomal irinotecan PEP02 (MM-398) or irinotecan with leucovorin/5-fluorouracil as second-line therapy in metastatic colorectal cancer.
    Cancer medicine, 2016, Volume: 5, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Quality of Life; Retreatment; Sucrose; Treatment Outcome

2016

Other Studies

6 other study(ies) available for sucrose and irinotecan

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A non-invasive method for detection of intestinal mucositis induced by different classes of chemotherapy drugs in the rat.
    Cancer biology & therapy, 2006, Volume: 5, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breath Tests; Camptothecin; Cyclophosphamide; Disease Models, Animal; DNA Topoisomerases, Type I; Doxorubicin; Etoposide; Female; Intestine, Small; Irinotecan; Mucositis; Rats; Sucrase; Sucrose; Topoisomerase I Inhibitors

2006
Activity of MM-398, nanoliposomal irinotecan (nal-IRI), in Ewing's family tumor xenografts is associated with high exposure of tumor to drug and high SLFN11 expression.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Mar-01, Volume: 21, Issue:5

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Disease Models, Animal; Drug Combinations; Female; Gene Expression; Humans; Irinotecan; Liposomes; Macrophages; Mice; Nuclear Proteins; Sarcoma, Ewing; Sucrose; Tissue Distribution; Tumor Burden; Xenograft Model Antitumor Assays

2015
The influence of trapping agents on the antitumor efficacy of irinotecan liposomes: head-to-head comparison of ammonium sulfate, sulfobutylether-β-cyclodextrin and sucrose octasulfate.
    Biomaterials science, 2018, Dec-18, Volume: 7, Issue:1

    Topics: Ammonium Sulfate; Animals; Antineoplastic Agents; beta-Cyclodextrins; Colonic Neoplasms; Delayed-Action Preparations; Drug Liberation; HT29 Cells; Humans; Irinotecan; Liposomes; Male; Mice, Nude; Rats, Sprague-Dawley; Sucrose; Topoisomerase I Inhibitors

2018
Effective co-encapsulation of doxorubicin and irinotecan for synergistic therapy using liposomes prepared with triethylammonium sucrose octasulfate as drug trapping agent.
    International journal of pharmaceutics, 2019, Feb-25, Volume: 557

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Doxorubicin; Drug Liberation; Drug Synergism; Erythrocytes; Female; Humans; Irinotecan; Liposomes; Methylamines; Mice, Inbred BALB C; Neoplasms; Rabbits; Rats, Sprague-Dawley; Sucrose; Tissue Distribution; Tumor Burden

2019
Inhibitory Activity of 4-
    Journal of microbiology and biotechnology, 2021, 11-28, Volume: 31, Issue:11

    Topics: Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Glucuronidase; Irinotecan; Molecular Docking Simulation; Molecular Dynamics Simulation; Polygala; Protein Structure, Tertiary; Sucrose

2021