sucrose has been researched along with irinotecan in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Butler, RN; Davidson, GP; Howarth, GS; Tooley, KL | 1 |
| Chen, LT; Dito, E; Ko, AH; Lin, YL; Ong, A; Shan, YS; Su, WC; Tempero, MA; Wang, YW; Yeh, CG | 1 |
| Calderon, RI; Cruz, RE; Drummond, DC; Fitzgerald, JB; Hall, CP; Hindle, A; Kang, MH; Ko, W; Lee, JS; Makena, MR; Paz, N; Reynolds, CP; Song, MM; Triche, TJ; Wang, J | 1 |
| André, T; Arbaud, C; Bachet, JB; Bennamoun, M; Bonnetain, F; Brusquant, D; Chibaudel, B; de Gramont, A; Dupuis, O; Garcia, ML; Hammel, P; Khalil, A; Larsen, AK; Louvet, C; Maindrault-Gœbel, F; Tournigand, C; Wang, YW; Yeh, CG | 1 |
| Fu, J; Guo, M; Liu, D; Liu, H; Sun, B; Wei, W; Yang, W; Yang, Z | 1 |
| Chi, D; Liu, J; Pan, S; Wang, D; Wang, X; Wang, Y; Zhao, L | 1 |
| Huh, YC; Hur, M; Kim, JH; Kim, YH; Koo, SC; Lee, YJ; Moon, YH; Park, WT; Vinh, LB; Yang, SY | 1 |
2 trial(s) available for sucrose and irinotecan
| Article | Year |
|---|---|
A multinational phase 2 study of nanoliposomal irinotecan sucrosofate (PEP02, MM-398) for patients with gemcitabine-refractory metastatic pancreatic cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Disease-Free Survival; Drug Combinations; Female; Humans; Irinotecan; Liposomes; Male; Middle Aged; Pancreatic Neoplasms; Salvage Therapy; Sucrose; Treatment Outcome | 2013 |
PEPCOL: a GERCOR randomized phase II study of nanoliposomal irinotecan PEP02 (MM-398) or irinotecan with leucovorin/5-fluorouracil as second-line therapy in metastatic colorectal cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Quality of Life; Retreatment; Sucrose; Treatment Outcome | 2016 |
6 other study(ies) available for sucrose and irinotecan
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A non-invasive method for detection of intestinal mucositis induced by different classes of chemotherapy drugs in the rat.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breath Tests; Camptothecin; Cyclophosphamide; Disease Models, Animal; DNA Topoisomerases, Type I; Doxorubicin; Etoposide; Female; Intestine, Small; Irinotecan; Mucositis; Rats; Sucrase; Sucrose; Topoisomerase I Inhibitors | 2006 |
Activity of MM-398, nanoliposomal irinotecan (nal-IRI), in Ewing's family tumor xenografts is associated with high exposure of tumor to drug and high SLFN11 expression.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Disease Models, Animal; Drug Combinations; Female; Gene Expression; Humans; Irinotecan; Liposomes; Macrophages; Mice; Nuclear Proteins; Sarcoma, Ewing; Sucrose; Tissue Distribution; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
The influence of trapping agents on the antitumor efficacy of irinotecan liposomes: head-to-head comparison of ammonium sulfate, sulfobutylether-β-cyclodextrin and sucrose octasulfate.
Topics: Ammonium Sulfate; Animals; Antineoplastic Agents; beta-Cyclodextrins; Colonic Neoplasms; Delayed-Action Preparations; Drug Liberation; HT29 Cells; Humans; Irinotecan; Liposomes; Male; Mice, Nude; Rats, Sprague-Dawley; Sucrose; Topoisomerase I Inhibitors | 2018 |
Effective co-encapsulation of doxorubicin and irinotecan for synergistic therapy using liposomes prepared with triethylammonium sucrose octasulfate as drug trapping agent.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Doxorubicin; Drug Liberation; Drug Synergism; Erythrocytes; Female; Humans; Irinotecan; Liposomes; Methylamines; Mice, Inbred BALB C; Neoplasms; Rabbits; Rats, Sprague-Dawley; Sucrose; Tissue Distribution; Tumor Burden | 2019 |
Inhibitory Activity of 4-
Topics: Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Glucuronidase; Irinotecan; Molecular Docking Simulation; Molecular Dynamics Simulation; Polygala; Protein Structure, Tertiary; Sucrose | 2021 |