Page last updated: 2024-08-16

succinylacetone and aminolevulinic acid

succinylacetone has been researched along with aminolevulinic acid in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19905 (21.74)18.7374
1990's12 (52.17)18.2507
2000's4 (17.39)29.6817
2010's2 (8.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Padmanaban, G; Surolia, N1
Hjalmarson, O; Holme, E; Lindstedt, S; Lock, EA; Strandvik, B1
Bloomer, JR; Freese, D; Glock, M; Pascual-Leone, A; Payne, W; Rank, JM; Sharp, H1
Carter, BE; Moses, LC; Roth, KS; Spencer, PD1
Ascher, N; Bloomer, JR; Freese, DK; Ramnaraine, ML; Sharp, HL; Tuchman, M1
Graber, SG; Woodworth, RC1
De Matteis, F; Ray, DE1
Fällström, SP; Lindblad, B; Steen, G1
Baekmark, UB; Brandt, NJ; Christensen, E; Gregersen, N; Hjeds, H; Jacobsen, BB; Pedersen, JB1
Castro, M; Díaz, M; Gangoiti, J; García, MJ; Medina, E; Merinero, B; Pérez-Cerdá, C; Sanz, P; Ugarte, M1
Beukeveld, GJ; Bijsterveld, K; Schierbeek, H; Smit, GP; van Faassen, H; van Spronsen, FJ; Venekamp-Hoolsema, EE; Wolthers, BG1
Bensoussan, AL; Blanchard, H; Bruneau, N; LaBerge, JM; Luks, FI; St-Vil, D1
Chan, RY; Kühn, LC; Ponka, P; Schulman, HM; Seiser, C1
Baumgartner, M; Bogdan, A; Callebert, J; Deybach, JC; Nordmann, Y; Puy, H; Touitou, Y; Voisin, P1
Hayakawa, T; Kawasaki, N; Morimoto, K; Tanimoto, T1
Barkaoui, E; Bernard, O; Debray, D; Habès, D; Ogier, H1
Berg, K; Dubbelman, TM; Gederaas, OA; Lagerberg, JW; Rasch, MH1
Bandy, B; Bechara, EJ; Costa, CA; de Barros, MP; Pinto, AM; Rocha, ME1
Dailey, HA; Woodard, SI1
Brindley, AA; Cooper, JB; Erskine, PT; Newbold, R; Shoolingin-Jordan, PM; Warren, MJ; Wood, SP1
Laftah, AH; Peters, TJ; Raja, KB; Simpson, RJ1
Adams, MA; Benjamin, CD; Bourque, SL; Nakatsu, K1
Qiu, B; Ren, C; Xiong, X; Zhi, T; Zhou, Z; Zhu, Q1

Trials

1 trial(s) available for succinylacetone and aminolevulinic acid

ArticleYear
Hematin therapy for the neurologic crisis of tyrosinemia.
    The Journal of pediatrics, 1991, Volume: 118, Issue:1

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminolevulinic Acid; Heme; Hemin; Heptanoates; Humans; Infant; Liver Transplantation; Male; Tyrosine

1991

Other Studies

22 other study(ies) available for succinylacetone and aminolevulinic acid

ArticleYear
de novo biosynthesis of heme offers a new chemotherapeutic target in the human malarial parasite.
    Biochemical and biophysical research communications, 1992, Sep-16, Volume: 187, Issue:2

    Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Glutamates; Glutamic Acid; Heme; Heptanoates; Isoleucine; Plasmodium falciparum; Porphobilinogen Synthase; Protein Biosynthesis

1992
Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase.
    Lancet (London, England), 1992, Oct-03, Volume: 340, Issue:8823

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Acetoacetates; alpha-Fetoproteins; Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Child; Child, Preschool; Cyclohexanones; Erythrocytes; Heptanoates; Humans; Hydroxybenzoates; Infant; Kidney Tubules; Liver; Nitrobenzoates; Phenylalanine; Phosphates; Porphobilinogen Synthase; Proteinuria; Tyrosine

1992
On rat renal aminolevulinate transport and metabolism in experimental Fanconi syndrome.
    Biochemical medicine and metabolic biology, 1990, Volume: 44, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Animals; Biological Transport, Active; Fanconi Syndrome; Heme; Heptanoates; In Vitro Techniques; Kidney Tubules; Male; Maleates; Microvilli; Porphobilinogen Synthase; Rats; Rats, Inbred Strains; Tyrosine

1990
Contribution of extrahepatic tissues to biochemical abnormalities in hereditary tyrosinemia type I: study of three patients after liver transplantation.
    The Journal of pediatrics, 1987, Volume: 110, Issue:3

    Topics: Acetoacetates; Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Child, Preschool; Female; Heptanoates; Humans; Infant; Liver Transplantation; Male; Porphobilinogen Synthase; Tyrosine

1987
Myoglobin expression in L6 muscle cells. Role of differentiation and heme.
    The Journal of biological chemistry, 1986, Jul-15, Volume: 261, Issue:20

    Topics: Aminolevulinic Acid; Animals; Cell Differentiation; Cell Line; Cytarabine; DNA; Ferric Compounds; Heme; Hemin; Heptanoates; Muscles; Myoglobin; Porphobilinogen Synthase; Rats

1986
Studied on cerebellar haem metabolism in the rat in vivo.
    Journal of neurochemistry, 1982, Volume: 39, Issue:2

    Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Cerebellum; Feedback; Heme; Heptanoates; Kinetics; Male; Porphobilinogen Synthase; Porphyrins; Rats; Rats, Inbred Strains; Tissue Distribution

1982
On the renal tubular damage in hereditary tyrosinemia and on the formation of succinylacetoacetate and succinylacetone.
    Acta paediatrica Scandinavica, 1981, Volume: 70, Issue:3

    Topics: Acetoacetates; Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Child; Heptanoates; Homogentisic Acid; Humans; Infant; Keto Acids; Kidney Diseases; Kidney Tubules; Male; Phenylalanine; Proteinuria; Tyrosine

1981
Urinary excretion of succinylacetone and delta-aminolevulinic acid in patients with hereditary tyrosinemia.
    Clinica chimica acta; international journal of clinical chemistry, 1981, Nov-11, Volume: 116, Issue:3

    Topics: Acetoacetates; Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Female; Fumarates; Heptanoates; Heptanoic Acids; Humans; Hydrolases; Infant; Keto Acids; Levulinic Acids; Male; Models, Biological; Tyrosine

1981
Liver transplantation in nine Spanish patients with tyrosinaemia type I.
    Journal of inherited metabolic disease, 1995, Volume: 18, Issue:2

    Topics: Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Enzyme Inhibitors; Graft Rejection; Heptanoates; Humans; Infant; Infant, Newborn; Liver Transplantation; Porphobilinogen Synthase; Spain; Treatment Outcome; Tyrosine

1995
Hereditary tyrosinaemia type I: a long-term study of the relationship between the urinary excretions of succinylacetone and delta-aminolevulinic acid.
    Journal of inherited metabolic disease, 1993, Volume: 16, Issue:6

    Topics: Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Child, Preschool; Creatinine; Heptanoates; Humans; Infant; Liver Transplantation; Male; Tyrosine

1993
[Surgical and metabolic aspects of liver transplantation for tyrosinemia].
    Annales de chirurgie, 1993, Volume: 47, Issue:9

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Central Nervous System Diseases; Child; Child, Preschool; Female; Heptanoates; Humans; Infant; Kidney Function Tests; Kidney Transplantation; Liver Failure; Liver Transplantation; Male; Postoperative Care; Preoperative Care; Quebec; Renal Insufficiency; Tyrosine

1993
Regulation of transferrin receptor mRNA expression. Distinct regulatory features in erythroid cells.
    European journal of biochemistry, 1994, Mar-15, Volume: 220, Issue:3

    Topics: Aminolevulinic Acid; Animals; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Erythroid Precursor Cells; Gene Expression Regulation; Heme; Heptanoates; Iron; Iron-Regulatory Proteins; Isoniazid; Mice; Receptors, Transferrin; RNA-Binding Proteins; RNA, Messenger; Transcription, Genetic

1994
Increased delta aminolevulinic acid and decreased pineal melatonin production. A common event in acute porphyria studies in the rat.
    The Journal of clinical investigation, 1996, Jan-01, Volume: 97, Issue:1

    Topics: Acetylserotonin O-Methyltransferase; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aminolevulinic Acid; Animals; Arylamine N-Acetyltransferase; Cells, Cultured; Enzyme Inhibitors; gamma-Aminobutyric Acid; Heme; Heptanoates; In Vitro Techniques; Isoproterenol; Male; Melatonin; Norepinephrine; Photoperiod; Pineal Gland; Porphobilinogen Synthase; Porphyria, Acute Intermittent; Rats; Rats, Wistar; Tryptophan

1996
Control of hemoglobin synthesis in erythroid differentiating K562 cells. I. Role of iron in erythroid cell heme synthesis.
    Archives of biochemistry and biophysics, 1996, Apr-15, Volume: 328, Issue:2

    Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Culture Media; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Glycophorins; Hemoglobins; Heptanoates; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Transferrin; Tumor Cells, Cultured

1996
[Favorable outcome of treatment with NTBC of acute liver insufficiency disclosing hereditary tyrosinemia type I].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1999, Volume: 6, Issue:5

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Acute Disease; Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Cyclohexanones; Enzyme Inhibitors; Female; Follow-Up Studies; Heptanoates; Humans; Infant; Infant, Newborn; Liver Failure; Male; Methionine; Nitrobenzoates; Porphobilinogen Synthase; Treatment Outcome; Tyrosine

1999
Photodynamically induced effects in colon carcinoma cells (WiDr) by endogenous photosensitizers generated by incubation with 5-aminolaevulinic acid.
    Journal of photochemistry and photobiology. B, Biology, 1999, Volume: 49, Issue:2-3

    Topics: Adenosine Triphosphate; Aminolevulinic Acid; Biomarkers, Tumor; Colonic Neoplasms; Fluorescent Dyes; Heptanoates; Humans; Microscopy, Confocal; Microscopy, Fluorescence; Oxygen Consumption; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Rhodamine 123; Time Factors; Tumor Cells, Cultured

1999
Iron mobilization by succinylacetone methyl ester in rats. A model study for hereditary tyrosinemia and porphyrias characterized by 5-aminolevulinic acid overload.
    Free radical research, 2000, Volume: 32, Issue:4

    Topics: Aminolevulinic Acid; Animals; Brain; Enzyme Inhibitors; Ferritins; Heptanoates; Iron; Liver; Male; Methylation; Porphobilinogen Synthase; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Transferrin

2000
Multiple regulatory steps in erythroid heme biosynthesis.
    Archives of biochemistry and biophysics, 2000, Dec-15, Volume: 384, Issue:2

    Topics: Aminolevulinic Acid; Animals; Enzyme Inhibitors; Erythroid Precursor Cells; Erythropoiesis; Heme; Heptanoates; Iron; Kinetics; Leukemia, Erythroblastic, Acute; Mice; Porphyrins; Tumor Cells, Cultured

2000
The x-ray structure of yeast 5-aminolaevulinic acid dehydratase complexed with substrate and three inhibitors.
    Journal of molecular biology, 2001, Sep-07, Volume: 312, Issue:1

    Topics: Aminolevulinic Acid; Binding, Competitive; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Heptanoates; Humans; Levulinic Acids; Lysine; Models, Molecular; Porphobilinogen Synthase; Protein Conformation; Tyrosinemias; Yeasts

2001
The effect of haem biosynthesis inhibitors and inducers on intestinal iron absorption and liver haem biosynthetic enzyme activities.
    Toxicology and applied pharmacology, 2008, Jun-15, Volume: 229, Issue:3

    Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Antimicrobial Cationic Peptides; Duodenum; Enzyme Inhibitors; Heme; Hepcidins; Heptanoates; Intestinal Absorption; Iron Compounds; Male; Mice; Porphobilinogen; Porphobilinogen Synthase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2008
Lack of hemodynamic effects after extended heme synthesis inhibition by succinylacetone in rats.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 333, Issue:1

    Topics: Aminolevulinic Acid; Animals; Blood Pressure; Guanylate Cyclase; Heme; Hemodynamics; Heptanoates; Hypertension; Kidney; Male; Nitric Oxide Synthase; Organ Specificity; Porphobilinogen Synthase; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sodium; Soluble Guanylyl Cyclase

2010
Loss of fumarylacetoacetate hydrolase causes light-dependent increases in protochlorophyllide and cell death in Arabidopsis.
    The Plant journal : for cell and molecular biology, 2019, Volume: 98, Issue:4

    Topics: Aldehyde Oxidoreductases; Aminolevulinic Acid; Arabidopsis; Arabidopsis Proteins; Cell Death; Chlorophyll; Gene Expression Regulation, Plant; Heptanoates; Hydro-Lyases; Hydrolases; Light; Lyases; Oxygen; Protochlorophyllide; Reactive Oxygen Species; Seedlings; Transcriptome

2019