succinimide has been researched along with aspartic acid in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.57) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 9 (32.14) | 29.6817 |
| 2010's | 9 (32.14) | 24.3611 |
| 2020's | 3 (10.71) | 2.80 |
| Authors | Studies |
|---|---|
| Cabonce, MA; Duffin, KL; Kolodziej, EW; Schlittler, MR; Siegel, NR; Smith, CE; Toren, PC; Tou, JS; Violand, BN; Zobel, JF | 1 |
| Benkovic, SJ; Gibbs, RA; Taylor, S | 1 |
| Chiappinelli, L; Filtri, P; Mancini, V; Pessi, A | 1 |
| Clarke, S; McFadden, PN | 1 |
| Aswad, DW; Buckley, D; Eberlein, G; Mischak, R; Paranandi, MV; Shahrokh, Z; Stratton, P; Wang, YJ | 1 |
| Miyawaki, K; Noguchi, S; Satow, Y | 1 |
| Chang, BS; Chow, DT; Haniu, M; Hui, JO; Katta, V; Markell, D; Nixon, L; Robinson, JH; Rohde, MF | 1 |
| Benson, MD; Kluve-Beckerman, B; Liepnieks, JJ; Orpiszewski, J; Schormann, N | 1 |
| Bossemeyer, D; Kinzel, V; König, N; Lehmann, WD; Pipkorn, R | 1 |
| Capasso, S; Di Cerbo, P | 1 |
| Clarke, S; Houk, KN; Radkiewicz, JL; Zipse, H | 1 |
| Athmer, L; Georges, F; Kindrachuk, J; Napper, S | 1 |
| Bondarenko, PV; Chelius, D; Chu, GC; Jacob, J; Xiao, G | 1 |
| Groebe, K; Schrattenholz, A; Soskić, V | 1 |
| Delbaere, LT; Napper, S; Prasad, L | 1 |
| Aviyente, V; Catak, S; Monard, G; Ruiz-López, MF | 1 |
| Kobayashi, K; Oda, A; Takahashi, O | 1 |
| Fujii, N; Nakagomi, K; Sadakane, Y | 1 |
| Katta, V; Zhang, J | 1 |
| Aki, K; Fujii, N | 1 |
| Kirikoshi, R; Manabe, N; Takahashi, O | 2 |
| Aki, K; Okamura, E | 1 |
| Friedrich, MG; Schey, KL; Truscott, RJW; Wang, Z | 1 |
| Fukuyoshi, S; Kato, K; Kurimoto, E; Nakayoshi, T; Oda, A | 1 |
| Bautista, J; Cao, X; Chen, Z; Das, TK; Hershey, N; Ludwig, R; Tao, L; Zeng, M; Zhou, K | 1 |
| Fukuyoshi, S; Kato, K; Kurimoto, E; Nakayoshi, T; Oda, A; Takahashi, H; Takahashi, O | 1 |
| Chemmalil, L; Ding, J; Kuang, J; Li, ZJ; Mussa, N; Song, Y; Tao, Y | 1 |
1 review(s) available for succinimide and aspartic acid
| Article | Year |
|---|---|
Nonenzymatic posttranslational protein modifications in ageing.
Topics: Aging; Asparagine; Aspartic Acid; Deamination; Glycation End Products, Advanced; Humans; Maillard Reaction; Mass Spectrometry; Oxidative Stress; Peptide Mapping; Protein Carbonylation; Protein Processing, Post-Translational; Reactive Nitrogen Species; Reactive Oxygen Species; Succinimides | 2008 |
27 other study(ies) available for succinimide and aspartic acid
| Article | Year |
|---|---|
Isolation and characterization of porcine somatotropin containing a succinimide residue in place of aspartate129.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Isoelectric Focusing; Mass Spectrometry; Molecular Weight; Peptide Fragments; Somatostatin; Succinimides; Swine; Trypsin | 1992 |
Antibody-catalyzed rearrangement of the peptide bond.
Topics: Antibodies, Catalytic; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Dipeptides; Glycine; Hydrogen-Ion Concentration; Kinetics; Peptides; Stereoisomerism; Succinimides | 1992 |
Side reactions in solid phase synthesis of histidine-containing peptides. Characterization of two major impurities by sample displacement chromatography and FAB-MS.
Topics: Amino Acid Sequence; Aspartic Acid; Chromatography, High Pressure Liquid; Histidine; Molecular Sequence Data; Peptides; Spectrometry, Mass, Fast Atom Bombardment; Succinimides | 1992 |
Conversion of isoaspartyl peptides to normal peptides: implications for the cellular repair of damaged proteins.
Topics: Animals; Aspartic Acid; Cattle; Erythrocytes; Gastrins; Humans; Kinetics; Models, Biological; Protein Methyltransferases; Protein O-Methyltransferase; Proteins; Succinimides; Tetragastrin | 1987 |
Major degradation products of basic fibroblast growth factor: detection of succinimide and iso-aspartate in place of aspartate.
Topics: Amino Acid Sequence; Aspartic Acid; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Fibroblast Growth Factor 2; Humans; Hydrolysis; Molecular Sequence Data; Protein Conformation; Recombinant Proteins; Succinimides | 1994 |
Succinimide and isoaspartate residues in the crystal structures of hen egg-white lysozyme complexed with tri-N-acetylchitotriose.
Topics: Animals; Aspartic Acid; Chickens; Crystallography, X-Ray; Egg White; Isoenzymes; Models, Molecular; Muramidase; Succinimides; Trisaccharides | 1998 |
Identification of Asp95 as the site of succinimide formation in recombinant human glial cell line-derived neurotrophic factor.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Glial Cell Line-Derived Neurotrophic Factor; Humans; Hydrolysis; Molecular Sequence Data; Nerve Growth Factors; Nerve Tissue Proteins; Peptide Fragments; Peptide Mapping; Recombinant Proteins; Sequence Analysis; Succinimides | 1998 |
Protein aging hypothesis of Alzheimer disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Aspartic Acid; Biopolymers; Cyclization; Humans; Isomerism; Models, Biological; Models, Molecular; Molecular Sequence Data; Plaque, Amyloid; Protein Folding; Protein Structure, Quaternary; Protein Structure, Secondary; Solubility; Succinimides; Thermodynamics; Time Factors | 2000 |
The amino terminus of PKA catalytic subunit--a site for introduction of posttranslational heterogeneities by deamidation: D-Asp2 and D-isoAsp2 containing isozymes.
Topics: Animals; Aspartic Acid; Catalytic Domain; Cattle; Chromatography, High Pressure Liquid; Cyclic AMP-Dependent Protein Kinases; Hydrolysis; Isoenzymes; Mass Spectrometry; Models, Chemical; Myocardium; Peptide Biosynthesis; Peptides; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Stereoisomerism; Succinimides | 2000 |
Kinetic and thermodynamic control of the relative yield of the deamidation of asparagine and isomerization of aspartic acid residues.
Topics: Animals; Asparagine; Aspartic Acid; Cattle; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Isomerism; Kinetics; Models, Chemical; Pancreas; Ribonuclease, Pancreatic; Succinimides; Temperature; Thermodynamics; Time Factors | 2000 |
Neighboring side chain effects on asparaginyl and aspartyl degradation: an ab initio study of the relationship between peptide conformation and backbone NH acidity.
Topics: Amides; Asparagine; Aspartic Acid; Glycine; Models, Chemical; Nitrogen; Protein Conformation; Proteins; Succinimides | 2001 |
The influence of protein structure on the products emerging from succinimide hydrolysis.
Topics: Aspartic Acid; Hydrolysis; Isoaspartic Acid; Phosphorylation; Proteins; Succinimides | 2002 |
18O labeling method for identification and quantification of succinimide in proteins.
Topics: Aspartic Acid; Hydrolysis; Kinetics; Molecular Structure; Oxygen Isotopes; Proteins; Sensitivity and Specificity; Succinimides; Tandem Mass Spectrometry; Time Factors; Water | 2007 |
Structural investigation of a phosphorylation-catalyzed, isoaspartate-free, protein succinimide: crystallographic structure of post-succinimide His15Asp histidine-containing protein.
Topics: Aspartic Acid; Bacterial Proteins; Catalysis; Crystallography, X-Ray; Escherichia coli; Hydrolysis; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Protein Structure, Tertiary; Succinimides | 2008 |
Deamidation of asparagine residues: direct hydrolysis versus succinimide-mediated deamidation mechanisms.
Topics: Amides; Asparagine; Aspartic Acid; Catalysis; Feasibility Studies; Hydrolysis; Models, Chemical; Models, Molecular; Molecular Conformation; Quantum Theory; Succinimides; Water | 2009 |
Computational modeling of the enolization in a direct mechanism of racemization of the aspartic acid residue.
Topics: Aspartic Acid; Models, Chemical; Models, Molecular; Stereoisomerism; Succinimides; Thermodynamics; Water | 2010 |
Determination of rate constants for β-linkage isomerization of three specific aspartyl residues in recombinant human αA-crystallin protein by reversed-phase HPLC.
Topics: Aspartic Acid; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Circular Dichroism; Crystallins; Humans; Kinetics; Least-Squares Analysis; Protein Structure, Secondary; Recombinant Proteins; Stereoisomerism; Succinimides; Temperature | 2011 |
Identification of Asp isomerization in proteins by ¹⁸O labeling and tandem mass spectrometry.
Topics: Amino Acid Sequence; Aspartic Acid; Chromatography, High Pressure Liquid; Hydrolysis; Isoaspartic Acid; Oxygen Radioisotopes; Peptide Mapping; Peptides; Protein Stability; Proteolysis; Staining and Labeling; Succinimides; Tandem Mass Spectrometry; Water | 2012 |
Kinetics of isomerization and inversion of aspartate 58 of αA-crystallin peptide mimics under physiological conditions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; alpha-Crystallin A Chain; Aspartic Acid; Child; Child, Preschool; Computer Simulation; Humans; Hydrogen-Ion Concentration; Hydrolysis; Infant; Infant, Newborn; Kinetics; Life Expectancy; Middle Aged; Models, Theoretical; Molecular Mimicry; Peptides; Stereoisomerism; Succinimides; Temperature; Young Adult | 2013 |
Roles of intramolecular and intermolecular hydrogen bonding in a three-water-assisted mechanism of succinimide formation from aspartic acid residues.
Topics: Aspartic Acid; Chemistry Techniques, Synthetic; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Succinimides; Water | 2014 |
Acetic acid can catalyze succinimide formation from aspartic acid residues by a concerted bond reorganization mechanism: a computational study.
Topics: Acetic Acid; Aspartic Acid; Catalysis; Cyclization; Models, Chemical; Models, Molecular; Succinimides | 2015 |
Kinetics of the competitive reactions of isomerization and peptide bond cleavage at l-α- and d-β-aspartyl residues in an αA-crystallin fragment.
Topics: alpha-Crystallin A Chain; Amino Acid Sequence; Aspartic Acid; Fluorenes; Humans; Kinetics; Lens, Crystalline; Oligopeptides; Protein Stability; Proteolysis; Stereoisomerism; Succinimides | 2017 |
Spontaneous cross-linking of proteins at aspartate and asparagine residues is mediated via a succinimide intermediate.
Topics: Aged; Amino Acid Sequence; Asparagine; Aspartic Acid; Humans; Lens, Crystalline; Succinimides | 2018 |
Computational Studies on Water-Catalyzed Mechanisms for Stereoinversion of Glutarimide Intermediates Formed from Glutamic Acid Residues in Aqueous Phase.
Topics: Aspartic Acid; Catalysis; Drug Resistance; Glutamic Acid; Molecular Structure; Peptides; Piperidones; Proteins; Stereoisomerism; Succinimides; Water | 2019 |
Structure-Function Assessment and High-Throughput Quantification of Site-Specific Aspartate Isomerization in Monoclonal Antibody Using a Novel Analytical Tool Kit.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Aspartic Acid; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Complementarity Determining Regions; Drug Compounding; Drug Stability; Drug Storage; High-Throughput Screening Assays; Immunoglobulin Fab Fragments; Immunoglobulin G; Isoaspartic Acid; Isomerism; Peptide Mapping; Protein Stability; Structure-Activity Relationship; Succinimides; Tandem Mass Spectrometry | 2020 |
Computational studies on nonenzymatic succinimide-formation mechanisms of the aspartic acid residues catalyzed by two water molecules.
Topics: Amides; Aspartic Acid; Catalysis; Cyclization; Isomerism; Models, Chemical; Models, Molecular; Nitrogen; Proteins; Succinimides; Water | 2020 |
Understanding the pathway and kinetics of aspartic acid isomerization in peptide mapping methods for monoclonal antibodies.
Topics: Antibodies, Monoclonal; Aspartic Acid; Chromatography, High Pressure Liquid; Isomerism; Kinetics; Peptide Mapping; Peptides; Succinimides; Tandem Mass Spectrometry | 2021 |