succinic acid and oxalylglycine

succinic acid has been researched along with oxalylglycine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Bello, SH; Liénard, BM; McDonough, MA; Mecinović, J; Ng, SS; Oppermann, U; Rose, NR; Schofield, CJ; Sun, Z1
Flashman, E; Hindley, N; Liénard, BM; Loenarz, C; Mecinović, J; Schofield, CJ; Sobott, F; Stubbs, CJ; Yeoh, KK1
Claridge, TD; Flashman, E; Leung, IK; Schofield, CJ; Yeoh, KK1
Claridge, TD; Demetriades, M; Hardy, AP; Kawamura, A; Lejeune, C; Leung, IK; Schofield, CJ; Smart, TJ; Szöllössi, A1
Abboud, MI; Langley, GW; Lohans, CT; Schofield, CJ1
Grabowski, DR; Guan, Y; Jha, BK; Maciejewski, JP; Phillips, JG; Tiwari, AD1
Burckhardt, BC; Burckhardt, G; Hagos, Y; Krick, W; Schley, G; Schödel, J; Willam, C1
Braun, MM; Chen, C; Damjanac, T; Hu, J; Maher, LJ; Zhang, Y1

Other Studies

8 other study(ies) available for succinic acid and oxalylglycine

ArticleYear
Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.
    Journal of medicinal chemistry, 2008, Nov-27, Volume: 51, Issue:22

    Topics: Crystallography, X-Ray; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Ketoglutaric Acids; Models, Molecular; Molecular Structure; Oxidoreductases, N-Demethylating; Protein Structure, Tertiary; Stereoisomerism; Structure-Activity Relationship

2008
Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure.
    Journal of medicinal chemistry, 2009, May-14, Volume: 52, Issue:9

    Topics: Animals; Catalytic Domain; Enzyme Inhibitors; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inhibitory Concentration 50; Mixed Function Oxygenases; Models, Molecular; Peptide Fragments; Protein Stability; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2009
Using NMR solvent water relaxation to investigate metalloenzyme-ligand binding interactions.
    Journal of medicinal chemistry, 2010, Jan-28, Volume: 53, Issue:2

    Topics: Drug Evaluation, Preclinical; Enzyme Inhibitors; Enzymes; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; Ligands; Magnetic Resonance Spectroscopy; Metalloproteins; Procollagen-Proline Dioxygenase; Protein Binding; Solvents; Water

2010
Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors.
    Journal of medicinal chemistry, 2013, Jan-24, Volume: 56, Issue:2

    Topics: Citric Acid Cycle; Enzyme Inhibitors; Humans; Ketoglutaric Acids; Ligands; Magnetic Resonance Spectroscopy; Oxygenases

2013
Inhibition of a viral prolyl hydroxylase.
    Bioorganic & medicinal chemistry, 2019, 06-15, Volume: 27, Issue:12

    Topics: Enzyme Assays; Hydroxylation; Hypoxia-Inducible Factor-Proline Dioxygenases; Ketoglutaric Acids; Oligopeptides; Phycodnaviridae; Procollagen-Proline Dioxygenase; Prolyl-Hydroxylase Inhibitors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2019
SAR insights into TET2 catalytic domain inhibition: Synthesis of 2-Hydroxy-4-Methylene-pentanedicarboxylates.
    Bioorganic & medicinal chemistry, 2021, 06-01, Volume: 39

    Topics: Catalytic Domain; Cell-Free System; Dicarboxylic Acids; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Humans; Molecular Docking Simulation; Spectrum Analysis; Structure-Activity Relationship; THP-1 Cells

2021
α-Ketoglutarate-related inhibitors of HIF prolyl hydroxylases are substrates of renal organic anion transporters 1 (OAT1) and 4 (OAT4).
    Pflugers Archiv : European journal of physiology, 2012, Volume: 464, Issue:4

    Topics: Amino Acids, Dicarboxylic; Biological Transport, Active; Dioxygenases; Estrone; HEK293 Cells; Humans; Hypoxia-Inducible Factor 1; Ketoglutaric Acids; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; p-Aminohippuric Acid; Procollagen-Proline Dioxygenase; Pyridines; Succinic Acid; Symporters

2012
Modeling succinate dehydrogenase loss disorders in C. elegans through effects on hypoxia-inducible factor.
    PloS one, 2019, Volume: 14, Issue:12

    Topics: Adrenal Gland Neoplasms; Amino Acids, Dicarboxylic; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Hypoxia; Disease Models, Animal; Drug Screening Assays, Antitumor; High-Throughput Screening Assays; Humans; Mutation; Paraganglioma; Pheochromocytoma; Succinate Dehydrogenase; Succinic Acid

2019