substance p has been researched along with neurokinin b in 397 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 97 (24.43) | 18.7374 |
| 1990's | 193 (48.61) | 18.2507 |
| 2000's | 55 (13.85) | 29.6817 |
| 2010's | 46 (11.59) | 24.3611 |
| 2020's | 6 (1.51) | 2.80 |
| Authors | Studies |
|---|---|
| Buck, SH; Harbeson, SL; Le, TB; Shatzer, SA | 1 |
| Deal, MJ; Hagan, RM; Ireland, SJ; Jordan, CC; McElroy, AB; Porter, B; Ross, BC; Stephens-Smith, M; Ward, P | 1 |
| Breliere, JC; Emonds-Alt, X; Golliot, F; Le Fur, G; Pointeau, P | 1 |
| Brawner, ME; Elshourbagy, NA; Foley, JJ; Giardina, GA; Griswold, DE; Hay, DW; Martin, LD; Medhurst, AD; Potts, W; Sarau, HM; Schmidt, DB; Webb, EF | 1 |
| Cascieri, MA; Harrison, T; Korsgaard, MP; Sadowski, S; Seabrook, GR; Swain, CJ | 1 |
| Allen, J; Gembitsky, DS; Lovas, S; Murnin, M; Murphy, RF; Otvös, FL | 1 |
| Ames, RS; Brawner, ME; Buckley, PT; Elshourbagy, NA; Feild, JA; Foley, JJ; Giardina, GA; Hay, DW; Luttmann, MA; Nuthulaganti, P; Sarau, HM; Schmidt, DB | 1 |
| Acker, GM; Advenier, C; Devillier, P; Frossard, N; Marsac, J; Regoli, D | 1 |
| Bellmann, R; Krause, JE; Marksteiner, J; Ortler, M; Sperk, G; Wahler, R | 1 |
| North, RA; Shen, KZ | 1 |
| Dorsett, JA; Mandel, KG; Yau, WM; Youther, ML | 1 |
| Fong, TM; Huang, RR; Strader, CD; Yu, H | 1 |
| Czarnobilski, K; Gustaw, P; Jaworek, J; Konturek, SJ; Pawlik, WW; Sendur, R; Yanaihara, N | 1 |
| Desban, M; Gauchy, C; Glowinski, J; Kemel, ML; Tremblay, L | 1 |
| Fong, TM; Huang, RR; Strader, CD | 1 |
| Krause, JE; Marksteiner, J; Saria, A | 1 |
| Zilov, VG | 1 |
| Chrétien, L; Guillemette, G; Regoli, D; Tousignant, C | 1 |
| Flowers, JM; Hall, JM; Morton, IK | 1 |
| Chang, FY; Lee, SD; Wang, PS; Yeh, GH | 2 |
| Hyman, PE; Kimura, S; McRoberts, JA; Snape, WJ; Tomomasa, T; Yuan, QX | 1 |
| Mio, M; Tasaka, K; Yoshida, T | 1 |
| Krause, JE; Marksteiner, J; Sperk, G | 1 |
| Akhundova, A; Fahrenholz, F; Gorbulev, V; Luzius, H | 1 |
| Brown, DR; Chandan, R; Larson, AA; Murray, CR; Parsons, AM; Seybold, VS; Soldani, G; Vogt, J | 1 |
| Bonici, B; Cuiné, F; Faucher, DC; Garret, C; Laduron, PM; Le Prado, N; Moussaoui, SM | 1 |
| Ferrell, WR; Lam, FY | 2 |
| Bowery, B; Hill, RG; Main, M; Seabrook, GR; Wood, N | 1 |
| Bonavera, JJ; Kalra, PS; Kalra, SP; Sahu, A | 1 |
| Hrabec, E; Hrabec, Z; Płucienniczak, A | 1 |
| Ertl, RF; Koyama, S; O'Neill, D; Rennard, SI; Robbins, RA; Rubinstein, I; Von Essen, SG | 1 |
| Albus, K; Chao, HH; Hicks, TP | 1 |
| Kanazawa, I; Konishi, S; Ogawa, T; Song, SY | 2 |
| Advenier, C; Dion, S; Drapeau, G; Naline, E; Nantel, F; Regoli, D; Rouissi, N | 1 |
| Brown, JR; Ewan, GB; Hagan, RM; Ireland, SJ; Jordan, CC; Ward, P | 1 |
| Bleicher, S; Freyer-Barski, A; Hahn, HL; Hümmer, B | 1 |
| Kimura, S | 1 |
| Dion, S; Drapeau, G; Nantel, F; Regoli, D; Rhaleb, NE; Rouissi, N | 2 |
| Brunelleschi, S; Fantozzi, R; Giotti, A; Ledda, F; Maggi, CA; Vanni, L | 1 |
| Otsuka, M; Yanagisawa, M | 1 |
| Couture, R; Jacques, L | 1 |
| Hellström, PM; Söder, O; Theodorsson, E | 1 |
| Gaedicke, G; McGregor, GP; Voigt, K | 1 |
| Geppetti, P; Grassi, J; Maillet, S; Mantellini, P; Renzi, D; Santicioli, P; Surrenti, C; Theodorsson, E | 1 |
| Jew, JY; Maher, JW; Sandler, AD; Schlegel, JF; Schmidt, CD; Weinstock, JV; Williams, TH | 1 |
| Brunelleschi, S; Fantozzi, R; Giotti, A; Tarli, S | 1 |
| Brunelleschi, S; Ceni, E; Fantozzi, R; Giotti, A | 1 |
| Cherniack, NS; Haxhiu, MA; van Lunteren, E | 1 |
| Shinkai, M; Takayanagi, I | 1 |
| Ball, DI; Coleman, RA; Sheldrick, RL | 1 |
| Hall, JM; Morton, IK | 2 |
| Coy, DH; Holst, JJ; Poulsen, SS; Schjoldager, B; Schmidt, P | 1 |
| Rance, NE; Young, WS | 1 |
| Munekata, E | 1 |
| Ball, JM; Bloom, SR; Cardoso, HM; Ghatei, MA; Lee, YC; Stock, MJ; Williams, G | 1 |
| Denis, P; Elena, PP; Fardin, V; Laroche, L; Nordmann, JP; Rostene, W; Saraux, H | 1 |
| Buchanan, KD; Fairweather, I; Halton, DW; Johnston, CF; McKay, DM; Shaw, C | 1 |
| Constantine, JW; Lebel, WS; Woody, HA | 1 |
| Lei, SZ; Lipkowski, AW; Wilcox, GL | 1 |
| Alafaci, C; Edvinsson, L; Jansen, I; McCulloch, J; Uddman, R | 1 |
| Barsacchi, P; Criscuoli, M; Lucacchini, A; Renzetti, AR | 1 |
| Oblin, A; Zivkovic, B | 1 |
| Kambam, JR; Kruskal, JB; Naukam, RJ; Parris, WC | 1 |
| Barnes, PJ; Kuo, HP; Rogers, DF; Rohde, JA; Tokuyama, K | 1 |
| Herrera-Marschitz, M; Reid, MS; Ungerstedt, U | 1 |
| De Caro, G; Massi, M; Perfumi, M; Polidori, C; Pompei, PL | 1 |
| Kato, T; Shinkai, M; Takayanagi, I | 1 |
| Giuliani, S; Maggi, CA; Patacchini, R; Santicioli, P | 1 |
| Braunstein, G; Fajac, I; Frossard, N; Lacronique, J | 1 |
| Boussougou, M; Jukic, D; Laprise, R; Regoli, D; Rouissi, N | 1 |
| Beresford, IJ; Deal, MJ; Hagan, RM; Ireland, SJ; Jordan, CC; Ward, P | 1 |
| Buck, SH; Fanger, BO; van Giersbergen, PL | 1 |
| Dube, G; Kalra, PS; Kalra, SP; Sahu, A | 1 |
| Chang, FY; Ouyang, A; Sharp, D | 1 |
| Brodin, E; Lorens, SA; Paris, JM | 1 |
| Nakanishi, S; Ohkubo, H | 1 |
| Luk, DE; Nolan, PN; Staszewska-Woolley, J | 1 |
| Kawashima, K; Kobayashi, N; Onishi, Y; Otsuka, M; Sakuma, M; Yanagisawa, M; Yoshioka, K | 1 |
| Brodin, E; Franck, J; Fried, G; Fried, K; Rosén, A; Yamamoto, Y | 1 |
| Claing, A; D'Orléans-Juste, P; Regoli, D; Télémaque, S; Warner, TD | 1 |
| Kayser, H; Schemann, M | 1 |
| Drapeau, G; Guillemain, I; Imhoff, V; Regoli, D; Rollandy, I; Rossignol, B | 1 |
| Kanazawa, I | 1 |
| Brodin, E; Lindgren, PG; Lundberg, JM; Norheim, I; Oberg, K; Tatemoto, K; Theodorsson-Norheim, E | 1 |
| Hannah, PA; Hunter, JC; Maggio, JE | 1 |
| Gamse, R; Saria, A | 1 |
| Amann, R; Holzer-Petsche, U; Lembeck, F; Schimek, E | 1 |
| Bitar, KN; Grider, JR; Makhlouf, GM; Souquet, JC | 2 |
| Chorev, M; Friedman, ZY; Gilon, C; Laufer, R; Selinger, Z; Wormser, U | 1 |
| Kanazawa, I; Kimura, S; Ogawa, T | 1 |
| Kamiya, H; Takano, Y; Takeda, Y; Yamada, K | 1 |
| Goto, K; Kanazawa, I; Kubo, K; Munekata, E; Osakada, F | 1 |
| Eimerl, J; Ezra, D; Feuerstein, G; Goldstein, RE; Laurindo, FR; Peck, CC | 1 |
| Maggio, JE | 1 |
| Asseraf, A; Descours, B; Devillier, P; Marsac, J; Regoli, D; Renoux, M | 1 |
| D'Orléans-Juste, P; Dion, S; Drapeau, G; Regoli, D | 2 |
| Beaujouan, JC; Bergström, L; Chassaing, G; Glowinski, J; Julien, S; Lavielle, S; Marquet, A; Torrens, Y | 1 |
| Glowinski, J; Petit, F | 1 |
| Jacoby, HI; Lopez, I; Vaught, JL; Wright, D | 1 |
| Beaujouan, JC; Bergström, L; Besseyre, J; Chassaing, G; Glowinski, J; Lavielle, S; Marquet, A; Torrens, Y | 1 |
| Fujiwara, M; Kanazawa, I; Masuo, Y; Taniguchi, T | 1 |
| Bartfai, T; Solti, M | 1 |
| Arai, H; Emson, PC | 1 |
| Goode, TL; Raffa, RB; Scott, RW | 1 |
| Hisayama, T; Hosoki, R; Takayanagi, I | 1 |
| Kuwahara, A; Yanaihara, N | 1 |
| Abelli, L; Giuliani, S; Maggi, CA; Meli, A; Regoli, D; Santicioli, P | 1 |
| Brodin, E; Ogren, SO; Theodorsson-Norheim, E | 1 |
| Brown, JR; Hunter, JC; Kilpatrick, GJ | 1 |
| Fujiwara, M; Muramatsu, I; Nakanishi, S | 1 |
| Cuello, AC | 1 |
| Gamse, R; Jancsó, G; Posch, M; Saria, A | 1 |
| D'Orléans-Juste, P; Dion, S; Drapeau, G; Regoli, D; Rhaleb, NE; Rouissi, NE | 1 |
| Conrath, M; Couraud, JY; Drapeau, G; Frobert, Y; Grassi, J; Pradelles, P; Regoli, D; Renzi, D | 1 |
| Dourish, CT; Iversen, LL; Iversen, SD; Stoessl, AJ; Williams, BJ; Young, SC | 1 |
| Beaujouan, JC; Bergström, L; Chassaing, G; d'Orléans-Juste, P; Dion, S; Julien, S; Lavielle, S; Marquet, A; Ploux, O; Regoli, D | 1 |
| Regoli, D | 1 |
| Diez-Guerra, FJ; Emson, PC; Richardson, PJ | 1 |
| Basbaum, CB; Borson, DB; Graf, PD; Nadel, JA; Sekizawa, K; Tamaoki, J | 1 |
| Galligan, JJ; North, RA; Tokimasa, T | 1 |
| Arai, H; Carrasco, LH; Emson, PC | 1 |
| Del Rio, J; Molinero, MT | 1 |
| Barbanti, G; Beneforti, P; Cellerini, M; Maggi, CA; Meli, A; Patacchini, R; Rovero, P; Santicioli, P; Turini, D | 1 |
| Couture, R; Dorais, J; Laneuville, O | 1 |
| Barnes, PJ; Frossard, N; Grandordy, BM; Rhoden, KJ | 1 |
| Warden, MK; Young, WS | 1 |
| Wilcox, GL | 1 |
| Giuliani, S; Maggi, CA; Meli, A; Rovero, P | 1 |
| Alessandri, M; Amenta, F; Ballerini, G; Fanciullacci, M; Geppetti, P; Maggi, CA; Santicioli, P; Theodorsson-Norheim, E | 1 |
| Gates, T; Maggio, JE; Mantyh, CR; Mantyh, PW; Vigna, SR | 1 |
| Hamada, M; Hasegawa, S; Kimura, S; Nomura, A; Otsuka, M; Uchida, Y | 1 |
| Drapeau, G; Giuliani, S; Maggi, CA; Meli, A; Regoli, D; Rovero, P | 1 |
| Cuello, AC; Elliott, P; Escher, E; Neugebauer, W | 1 |
| Advenier, C; Devillier, P; Drapeau, G; Marsac, J; Regoli, D | 1 |
| Khalil, Z; Livett, BG; Marley, PD | 1 |
| Vaught, JL | 1 |
| Joos, GF; Pauwels, RA; van der Straeten, ME | 1 |
| de Caro, G; Gentili, L; Maggi, CA; Massi, M; Perfumi, M; Polidori, C | 1 |
| Koelbel, CB; Mayer, EA; Patel, A; Snape, WJ; van Deventer, G | 1 |
| Ho, FJ; Koelbel, CB; Mayer, EA; Patel, A; Reeve, JR; Snape, WJ | 1 |
| Beding-Barnekow, B; Brodin, E; Håkanson, R | 1 |
| Aursudkij, B; Barnes, PJ; Belvisi, MG; Evans, TW; Rogers, DF | 1 |
| Burgunder, JM; Young, WS | 2 |
| Couture, R; Marceau, F; Regoli, D; Tremblay, B | 1 |
| Brain, SD; Williams, TJ | 1 |
| Borson, DB; Iwamoto, I; Nadel, JA; Ueki, IF | 1 |
| Hamaoka, T; Kamiya, H; Matsuoka, Y; Nagashima, A; Takano, Y; Tateishi, K | 2 |
| Larsen, PJ; Mikkelsen, JD; Møller, M; Saermark, T; Vilhardt, H | 1 |
| Abelli, L; Astolfi, M; Conte, B; Maggi, CA; Meli, A; Parlani, M; Regoli, D; Rovero, P; Somma, V | 1 |
| Advenier, C; Bakdach, H; Devillier, P; Drapeau, G; Naline, E; Regoli, D; Toty, L | 1 |
| Davison, JS; Mathison, R | 1 |
| Bertrand, C; Landry, Y; Magneney, S; Mayer, M; Michelot, R; Schmitt, P; Tschirhart, E | 1 |
| Maggi, CA; Meli, A; Patacchini, R; Rovero, P | 1 |
| Couture, R; Drapeau, G; Jacques, L; Regoli, D | 1 |
| Apperl, A; Braunsteiner, H; Kieselbach, G; Konwalinka, G; Wiedermann, CJ; Wiedermann, FJ | 1 |
| Dalsgaard, CJ; Laurenzi, MA; Persson, MA; Ringdén, O | 1 |
| Barnes, PJ; McCormack, DG; Salonen, RO | 1 |
| Hicks, CR; Mizoguchi, H | 1 |
| Couture, R; Drapeau, G; Guimond, C; Laneuville, O; Regoli, D | 1 |
| Aursudkij, B; Barnes, PJ; Rogers, DF | 1 |
| Furukawa, K; Irie, K; Muraki, H; Nomoto, T | 1 |
| Anderson, K; Brecha, NC; Krause, JE; Sternini, C | 1 |
| Johnston, SA; Merali, Z | 1 |
| Cascieri, MA; Chicchi, GG; Liang, T | 1 |
| Goedert, M; Hunter, JC; Pinnock, RD | 1 |
| Brodin, E; Lindefors, N; Theodorsson-Norheim, E; Ungerstedt, U | 1 |
| Brodin, E; Hua, X; Lundberg, JM; Theodorsson-Norheim, E | 1 |
| Kanazawa, I; Matsuto, T; Munekata, E; Otsuka, M; Yanagisawa, M | 1 |
| Kanazawa, I; Kimura, S; Munekata, E; Ogawa, T | 1 |
| Goto, K; Kanazawa, I; Kimura, S; Ogawa, T; Sugita, Y | 1 |
| Pilapil, C; Quirion, R | 1 |
| Watson, SP | 1 |
| Jacoby, HI; Post, LJ; Vaught, JL; Wright, D | 1 |
| Kangawa, K; Masuda, H; Matsuo, H; Minamino, N | 1 |
| Broccardo, M; Improta, G; Severini, C | 1 |
| Myers, AC; Undem, BJ | 1 |
| Harlan, RE; Zhang, L | 1 |
| Boyle, SJ; Guard, S; McKnight, AT; Watling, KJ; Woodruff, GN | 1 |
| Cenarruzabeitia, E; Del Río, J; Lasheras, B; Ramírez, MJ | 2 |
| Cynader, MS; Gu, Q; Liu, Y | 1 |
| Baranauskas, G; Fisher, ND; Nistri, A | 1 |
| Couture, R; Picard, P; Regoli, D | 1 |
| Fredholm, BB; Johansson, B; Lindström, K | 1 |
| Bürger, E; Czernilofsky, AP; Himmler, A; Mayer, SK; Schäfer, R; Stratowa, C; Weyer, U | 1 |
| Bertrand, C; Da Silva, A; Landry, Y | 1 |
| Giolitti, A; Maggi, CA | 1 |
| Gomi, Y; Mizuno, K; Suzuki, N | 1 |
| Ishihara, H; Nagaki, M; Sasaki, T; Shimura, S; Shirato, K; Takishima, T | 1 |
| Bruce, TR; Rance, NE | 1 |
| Chung, FZ; Grimson, P; Guard, S; Madden, Z; Pinnock, R; Suman-Chauhan, N; Watling, K; Woodruff, G | 1 |
| Ashton, IK; Eisenstein, SM; Polak, JM; Walsh, DA | 1 |
| Giuliani, S; Maggi, CA; Zagorodnyuk, V | 1 |
| Arioli, F; Belloli, C; Beretta, C; Madonna, M | 1 |
| McDonald, TJ; Prokopiw, I | 1 |
| Lefebvre, RA; Smits, GJ | 1 |
| Arkinstall, S; Beresford, IJ; Hagan, RM; Ireland, SJ; Seale, PW; Stables, JM; Walsh, DM; Ward, P | 1 |
| Allen, CJ; Basbaum, AI; Ghilardi, JR; Liu, H; Maggio, JE; Mantyh, CR; Mantyh, PW; Rogers, SD; Vigna, SR | 1 |
| Krause, JE; McCarson, KE | 1 |
| Kitano, I; Matsunaga, T; Mori, N; Nario, K | 1 |
| Bowery, BJ; Hill, RG; Seabrook, GR | 1 |
| Maggi, CA; Quartara, L; Rovero, P | 1 |
| Fujimori, K; Inoue, K; Nakazawa, K | 1 |
| Andersson, KE; Ishizuka, O; Mattiasson, A | 1 |
| Fukuhara, S; Mukai, H; Munekata, E | 1 |
| Accili, EA; Brown, JC; Buchan, AM; Kwok, YN; Ledsome, JR | 1 |
| Culman, J; Klee, S; Spitznagel, H; Unger, T; Wiegand, B | 1 |
| Fong, TM; Huang, RR; Strader, CD; Vicario, PP | 1 |
| Killingsworth, CR; Shore, SA | 1 |
| Coy, DH; Jensen, RT; Lin, JT; Mantey, SA | 1 |
| Kanda, M; Kurahashi, K; Nakamura, S; Shimizu, Y; Shirahase, H; Usui, H | 1 |
| Barr, AJ; Watson, SP | 1 |
| Mak, JC; Meini, S; Rogers, DF; Rohde, JA | 1 |
| Håkanson, R; Wang, ZY | 1 |
| Cascieri, MA; Fong, TM; Huang, RR; Marko, O; Sadowski, S | 1 |
| Anding, P; Gao, XP; Lowe, J; Rennard, SI; Robbins, RA; Rubinstein, I; Snider, RM | 1 |
| Barrett, C; Dornan, WA; Malen, P; Short, K; Struthers, W; Vink, KL | 1 |
| Crossman, DC; Dashwood, MR; Fuller, RW; Taylor, GW; Wellings, R | 1 |
| Bersch, B; Koehl, P; Milon, A; Nakatani, Y; Ourisson, G | 1 |
| Conlon, JM; Homo-Delarche, F; Kerdelhue, B; Leboulenger, F; Pelletier, G; Vaglini, L; Vaudry, H; Wang, Y | 1 |
| Itoshima, T; Kato, N; Masui, A; Nakajima, T; Tsunashima, K; Yanaihara, N | 1 |
| Bertrand, C; Bunnett, NW; Debas, HT; Geppetti, P; Huber, O; Nadel, JA; Pellegrini, CA | 1 |
| Betts, WH; Halliday, DA; McNeil, JD; Scicchitano, R | 1 |
| Fuchikami, J; Isohama, Y; Kai, H; Miyata, T; Takahama, K | 1 |
| Konishi, S; Saito, K; Song, SY; Yamakuni, T | 1 |
| Jukic, D; Nguyen, QT; Regoli, D; Rouissi, N | 1 |
| Guo, JZ; Hagan, RM; Otsuka, M; Yanagisawa, M; Yoshioka, K | 1 |
| Hess, HJ; Kanai, Y; Lowe, JA; Nagahisa, A; Suga, O; Taniguchi, K; Tsuchiya, M | 1 |
| Humpel, C; Saria, A | 1 |
| Ahluwalia, A; Giuliani, S; Maggi, CA | 1 |
| Kondo, M; Konno, K; Sakai, A; Takemura, H; Tamaoki, J | 1 |
| Coleman, RA; Fischer, A; Magnussen, H; Rabe, KF; Sheldrick, RL | 1 |
| Horwell, DC; Howson, W; Ratcliffe, GS; Willems, HM | 1 |
| Chung, FZ; Oxender, DL; Tian, Y; Wu, LH | 1 |
| Chapman, RW; Danko, G; del Prado, M; Hey, JA | 1 |
| Kondo, M; Konno, K; Sakai, A; Tagaya, E; Takemura, H; Tamaoki, J | 1 |
| Marchionni, D; Nisato, D; Roccon, A | 1 |
| Martini-Luccarini, F; Puizillout, JJ; Reynaud, JC | 1 |
| Inoue, H; Koshihara, Y; Nagata, N | 1 |
| Chitano, P; Fabbri, LM; Lucchini, RE; Mapp, CE; Polak, JM; Springall, DR | 1 |
| Bertrand, C; Emanueli, C; Figini, M; Geppetti, P; Javdan, P | 1 |
| Fujii, T; Itaba, M; Kagaya, M; Miura, M; Sano, M; Shindo, T; Shioya, T | 1 |
| Brodbeck, RM; Bu, JY; Karpitskiy, VV; Krause, JE; Mentzer, JN; Schmidt, SK; Staveteig, PT; Tucker, JB | 1 |
| Martin, TV; Weiss, RM; Wheeler, MA | 1 |
| Hay, DW; Medhurst, AD; Parsons, AA; Roberts, JC | 1 |
| Andolfi, L; Bagnoli, P; Casini, G; Trasarti, L | 1 |
| Couture, R; Yuan, YD | 1 |
| Beaujouan, JC; Glowinski, J; Saffroy, M; Torrens, Y | 1 |
| Couture, R; Sgambato, V; Toma, N | 1 |
| O'Grady, SM; Vetter, AE | 1 |
| Chawla, MK; Gutierrez, GM; McMullen, NT; Rance, NE; Young, WS | 1 |
| Gobeil, F; Nguyen-Le, XK; Nsa Allogho, S; Pheng, LH; Regoli, D | 1 |
| Griswold, DE; Hay, DW; Martin, LD; Medhurst, AD; Parsons, AA | 1 |
| Ciucci, A; Manzini, S; Palma, C; Riitano, D; Werge, TM | 1 |
| MacNaughton, W; Moore, B; Vanner, S | 1 |
| Kondo, A; Ohmura, M; Saito, M | 1 |
| Bränström, R; Hellström, PM; Lördal, M | 1 |
| Cody, C; Jones, RS; Maubach, KA | 1 |
| Jino, H; Kanda, M; Kurahashi, K; Murase, K; Nakamura, S; Shirahase, H; Usui, H | 1 |
| Brechenmacher, C; Feltz, P; Larmet, Y; Rodeau, JL | 1 |
| Hadden, CE; Hicks, RP; McNair, SD; Whitehead, TL; Young, JK | 1 |
| Qiao, J; Tao, Z; Xiao, J; Zhao, C; Zhao, S | 1 |
| Bordin, G; Brunelleschi, S; Colangelo, D; Viano, I | 2 |
| Tao, Z; Xiao, J; Zhao, C | 1 |
| Endoh, T; Suzuki, T; Yamada, T | 1 |
| Buffington, CA; Wolfe, SA | 1 |
| Blanchet, F; Gauchy, C; Glowinski, J; Kemel, ML; Perez, S; Soubrié, P | 1 |
| Ciucci, A; Manzini, S; Palma, C; Werge, TM | 1 |
| Fukuhara, S; Matsushima, H; Mukai, H; Munekata, E; Shimizu, M | 1 |
| El-Agnaf, OM; Fitzpatrick, G; Glass, WK; Guthrie, DJ; Irvine, GB | 1 |
| Chen, HH; Kuo, HP | 1 |
| Guo, JZ; Otsuka, M; Yoshioka, K | 1 |
| Stahl, SM | 1 |
| Bianchi, B; Cappugi, P; Danesi, A; Giannotti, B; Ipponi, P; Johansson, O; Matucci, R; Rossi, R | 1 |
| Krause, JE; Roth, KA; Yunker, AM | 1 |
| Hellström, PM; Lördal, M | 1 |
| Braun, A; Gessner, R; Pfeufer, A; Renz, H; Wiebe, P | 1 |
| Broccardo, M; Improta, G; Tabacco, A | 1 |
| Ikeda, T; Minakata, H; Nomoto, K | 1 |
| Bredenbröker, D; Fehmann, H; Klüber, D; Lange, A; Wagner, U; Wichert, P | 1 |
| Calixto, JB; De Lima, TC; Ribeiro, SJ; Teixeira, RM | 1 |
| Geraghty, DP; Mazzone, SB | 2 |
| Krause, JE; McLeod, AL; Ribeiro-Da-Silva, A | 1 |
| Advenier, C; Daoui, S; Emonds-Alt, X; Lagente, V; Naline, E | 1 |
| Fleming, AJ; Lilley, A; Patak, EN; Pennefather, JN; Story, ME; Ziccone, S | 1 |
| Bulboacă, A; Pop, R | 1 |
| Calixto, JB; Campos, MM | 1 |
| Coupar, IM; Kerr, KP; Thai, B | 1 |
| Broccardo, M; Improta, G | 1 |
| Culmsee, C; Krieglstein, J; Schafer, MK; Stumm, R; Weihe, E | 1 |
| Bolle, P; Erspamer, V; Falconieri-Erspamer, G; Severini, C; Tucci, P | 1 |
| Krysiak, PS; Preiksaitis, HG | 1 |
| Ackley, MA; Asghar, AU; King, AE; Worsley, MA | 1 |
| Baird, AW; Goldhill, J; Moriarty, D; O'Donoghue, DP; Selve, N | 1 |
| Baulmann, J; Blume, A; Culman, J; Spitznagel, H; Unger, T | 1 |
| Marchetti, C; Nistri, A | 1 |
| Ehlers, CL; Jimenéz-Vasquez, P; Mathé, AA; Slawecki, CJ | 1 |
| Advenier, C; Daoui, S; Emonds-Alt, X; Gueudet, C; Le Fur, G; Maffrand, JP; Michaud, JC; Naline, E; Oury-Donat, F; Pascal, M; Poncelet, M; Proietto, V; Soubrié, P; Steinberg, R; Vilain, P | 1 |
| Akhtar, R; Brain, SD; Gerard, NP; Grant, AD | 1 |
| Hirano, K; Kanaide, H; Naito, S; Nishimura, J; Takahashi, R | 1 |
| Jones, RS; Stacey, AE; Woodhall, GL | 1 |
| Baude, A; Blondeau, C; Colin, I | 1 |
| Barbato, C; Calissano, P; Ciotti, MT; Mercanti, D; Severini, C | 1 |
| Baamonde, A; Candenas, ML; Hidalgo, A; Pennefather, JN; Pintado, CO; Pinto, FM; Sanchez, T | 1 |
| Cvetkovic, V; Fellmann, D; Griffond, B; Poncet, F; Risold, PY | 1 |
| Bolle, P; Severini, C; Tucci, P; Valeri, P | 1 |
| Bunnett, NW; Roosterman, D; Schmidlin, F | 1 |
| Li, ZW; Yang, YL; Yao, KH | 1 |
| Lao, LJ; Marvizon, JC; Song, B; Wang, X | 1 |
| Cunha-Vaz, JG; Gaspar, MN; Macedo, TR; Ribeiro, CA | 1 |
| de Francischi, JN; Lisboa, MC; Santos, JM; Tatsuo, MA; Turchetti-Maia, RM | 1 |
| Abbott, MA; Jeannotte, L; Joksimovic, M; Krieger, KE; Lueth, PA; Sonea, IM; Tuggle, CK | 1 |
| Marriott, I | 1 |
| Bost, KL; Nelson, DA | 1 |
| Morimoto, K; Mukaiyama, O; Nosaka, E; Takahashi, S; Yamashita, M | 1 |
| Han, SK; Herbison, AE; Todman, MG | 1 |
| Aguirre, JA; Coveñas, R; Gómez, A; Narváez, JA; Sánchez, L; Tramu, G | 1 |
| Gerspacher, M | 1 |
| Chan, MH; Kao, PC; Lin, YR | 1 |
| Hirsch, EC; Michel, PP; Salthun-Lassalle, B; Traver, S | 1 |
| Liashchenko, TP; Makarchuk, MIu; Spivak, LS; Vesel's'kyĭ, SP | 1 |
| Furuta, T; Kaneko, T; Polgár, E; Todd, A | 1 |
| Chrones, T; Kovac, JR; Preiksaitis, HG; Sims, SM | 1 |
| Fischer-Colbrie, R; Haas, G; Kieselbach, G; Kralinger, M; Krause, JE; Leierer, J; Nguyen, QA; Schmid, E; Stemberger, K; Teuchner, B; Troger, J | 1 |
| Candenas, ML; Fernández-Sánchez, M; Orea, A; Pintado, CO; Pinto, FM; Ravina, CG; Seda, M | 1 |
| Morimoto, K; Mukaiyama, O; Nosaka, E; Takahashi, S; Tsuchida, H; Yamashita, M | 1 |
| Cheng, L; Goulding, M; Lima, D; Liu, Y; Lopes, C; Ma, Q; Qian, Y; Turner, EE; Xu, Y | 1 |
| Aizawa, N; Imamura, T; Ishizuka, O; Nakayama, T; Nishizawa, O; Ogawa, T; Tanabe, T; Zhong, C | 1 |
| Aura Kullmann, F; de Groat, WC; Sculptoreanu, A | 1 |
| Rance, NE | 1 |
| Fukuhara, S; Kikuchi, M; Kiso, Y; Mukai, H; Munekata, E | 1 |
| Medd, AM; Simmons, MA; Sobotka-Briner, CD | 1 |
| Andersson, KE; Imamura, T; Ishizuka, O; Kurizaki, Y; Nakayama, T; Nishizawa, O; Ogawa, T; Tanabe, T; Zhong, C | 1 |
| Akcay, T; Atay, Z; Bereket, A; Canan, H; Gribble, FM; Guran, T; Kotan, LD; O'Rahilly, S; Porter, K; Reimann, F; Rocha, N; Semple, RK; Serin, A; Tolhurst, G; Topaloglu, AK; Turan, S | 1 |
| Cluderay, JE; Dada, A; Davies, CH; Dawson, LA; de la Flor, R; Hagan, JJ; Hill, MD; Jones, DN; Jones, GA; Langmead, CJ; Murkitt, GS; Smith, PW; Southam, E; Watson, JM; Wu, Z | 1 |
| Cline, MA; Khan, MS; Matsuda, K; Tachibana, T; Ueda, H | 1 |
| Bechrakis, N; Dietrich, H; Dimmer, A; Fischer-Colbrie, R; Kieselbach, G; Schmid, E; Teuchner, B; Troger, J | 1 |
| Altman, SN; Billings, HJ; Connors, JM; Goodman, RL; Hileman, SM; Holaskova, I; Jacobs, BH; Lehman, MN; McManus, CJ; Nestor, CC | 1 |
| Ali, B; Amin, NA; Ciofi, P; Plant, TM; Ramaswamy, S; Seminara, SB | 1 |
| Dhillo, WS; Jayasena, CN | 1 |
| Castellano, JM; Clifton, DK; McConkey, SM; Navarro, VM; Pineda, R; Pinilla, L; Ruiz-Pino, F; Steiner, RA; Tena-Sempere, M | 1 |
| Imamura, T; Ishikawa, M; Ishizuka, O; Kurizaki, Y; Nishizawa, O; Noguchi, W; Zhang, L | 1 |
| Couto, N; Moreira, A; Ramalho, R; Soares, R | 1 |
| Nagano, M; Oishi, T; Suzuki, H | 1 |
| Dacks, PA; Krajewski, SJ; Rance, NE | 1 |
| Akasaka, Y; Hatta, A; Inoue, H; Sakai, A; Suzuki, H; Takasu, K; Tsukahara, M | 1 |
| Blomenröhr, M; García-Galiano, D; Gaytan, F; Krajnc-Franken, MA; Leon, S; Manfredi-Lozano, M; Navarro, VM; Pinilla, L; Romero-Ruiz, A; Tena-Sempere, M; van Ingen Schenau, D; van Noort, PI | 1 |
| Grachev, P; Kinsey-Jones, JS; Li, XF; Lightman, SL; Lin, YS; Milligan, SR; O'Byrne, KT | 1 |
| Briscoe, AM; Davis, SM; Goodman, RL; Hileman, SM; Nestor, CC; Valent, M | 1 |
| Cynkier, A; Danilewicz, M; Erkiert-Polguj, A; Stasikowska-Kanicka, O; Sysa-Jędrzejowska, A; Wągrowska-Danilewicz, M; Waszczykowska, E; Zebrowska, A | 1 |
| Holzman, S; Hoon, MA; Mishra, SK | 1 |
| Bentsen, AH; Ciofi, P; Garcia-Galiano, D; Mikkelsen, JD; Navarro, VM; Pinilla, L; Ruiz-Pino, F; Sanchez-Garrido, MA; Steiner, RA; Tena-Sempere, M | 1 |
| di Domenico, AL; Grachev, P; Kinsey-Jones, JS; Li, XF; Lightman, SL; Millar, RP; O'Byrne, KT | 1 |
| Elsamani, L; Grachev, P; Hu, MH; Li, XF; Lightman, SL; Lin, YS; Millar, RP; O'Byrne, KT; Paterson, SJ | 1 |
| Mori, Y; Okamura, H; Sakamoto, K; Wakabayashi, Y; Yamamura, T | 1 |
| Chen, R; Lai, K; Liu, C; Luo, W; Zhong, N | 1 |
| Glidewell-Kenney, CA; Grove, AM; Iyer, AK; Meadows, JD; Mellon, PL; Shao, PP | 1 |
| Navarro, VM | 1 |
| Boehm, U; de Croft, S; Herbison, AE | 1 |
| Burger, LL; Moenter, SM; Ruka, KA | 2 |
| Deura, C; Fujii, N; Iwase, A; Kikkawa, F; Maeda, K; Minabe, S; Nakahara, T; Nakamura, S; Noguchi, T; Oishi, S; Tsukamura, H; Uenoyama, Y; Watanabe, Y | 1 |
| Bloom, SR; Borsay, BÁ; Ciofi, P; Dhillo, WS; Ghatei, MA; Herczeg, L; Hrabovszky, E; Liposits, Z; Rácz, K | 1 |
| Dani, JA; Dao, DQ; De Biasi, M; Perez, EE; Teng, Y | 1 |
| Grachev, P; Hu, MH; Li, SY; Li, XF; Lightman, SL; Millar, RP; O'Byrne, KT | 1 |
| Feixia, L; Jia, Z | 1 |
| Bloom, SR; Borsay, BÁ; Ciofi, P; Dhillo, WS; Ghatei, MA; Herczeg, L; Hrabovszky, E; Liposits, Z; Skrapits, K | 2 |
| Fujii, N; Matsuda, F; Misu, R; Noguchi, T; Ohkura, S; Ohno, H; Oishi, S; Okamura, H; Yamada, A; Yamamoto, K; Yamamura, T | 1 |
| Garcia-Galiano, D; Leon, S; Manfredi-Lozano, M; Navarro, VM; Pinilla, L; Roa, J; Ruiz-Pino, F; Sánchez-Garrido, MA; Tena-Sempere, M | 1 |
| Clarke, IJ; Li, Q; Millar, RP; Smith, JT | 1 |
| Almeida, TA; Bello, AR; Candenas, L; Gallardo-Castro, M; Pinto, FM; Tena-Sempere, M; Valladares, F | 1 |
| Leng, G; Ludwig, M; Millar, RP; Pineda, R; Sabatier, N | 1 |
| Coolen, LM; Fergani, C; Goodman, RL; Grachev, P; Hardy, SL; Lehman, MN; Mazzella, L; McCosh, RB; Newcomb, N | 1 |
| Goto, T; Hirabayashi, M; Ieda, N; Ikegami, K; Inoue, N; Maeda, KI; Maturana, AD; Minabe, S; Nakamura, S; Oishi, S; Sanbo, M; Sugimoto, A; Tsukamura, H; Uenoyama, Y | 1 |
| Garcia, JP; Guerriero, KA; Keen, KL; Kenealy, BP; Seminara, SB; Terasawa, E | 1 |
| Irahara, M; Iwasa, T; Kato, T; Kuwahara, A; Matsui, S; Matsuzaki, T; Mayila, Y; Munkhzaya, M; Tokui, T; Tungalagsuvd, A; Yanagihara, R; Yano, K | 1 |
| Arlt, W; Chan, YM; Cole, TR; Farooqi, IS; Fergani, C; Hall, JE; Jones, CM; León, S; Lippincott, MF; Navarro, VM; Seminara, SB; Shaw, ND; Stewart, SE; Talbi, R; Terasawa, E | 1 |
| Fergani, C; Gerutshang, A; León, S; Maguire, CA; Navarro, VM; Simavli, S; Talbi, R | 1 |
| Dees, WL; Hiney, JK; Srivastava, VK | 1 |
| Amodei, R; Coolen, LM; Corder, KR; Estill, CT; Gribbin, K; He, W; Jonker, SS; Lehman, MN; Lindgren, I; Roselli, CE; Stormshak, F; Whitler, W | 1 |
| Dong, L; Fei, X; Liu, D; Yuan, J; Zhang, C; Zhou, Y; Zhu, Y; Zhu, Z | 1 |
| Matsuyama, S; Miwa, M; Morita, Y; Nakamura, S; Ohkura, S; Wakabayashi, Y; Yamamura, T | 1 |
| Chen, Y; Gao, W; Gao, Y; Lu, W | 1 |
| Jung, HJ; Priefer, R | 1 |
| Boyle, CA; Hu, B; Lei, S; Mastrud, MR; Quaintance, KL | 1 |
19 review(s) available for substance p and neurokinin b
| Article | Year |
|---|---|
[Tachykinins in the central mechanisms of biological motivation].
Topics: Animals; Appetite; Appetite Depressants; Brain; Feeding Behavior; Models, Psychological; Neurokinin A; Neurokinin B; Rabbits; Rats; Rats, Sprague-Dawley; Substance P; Tachykinins | 1992 |
[Biosynthesis of substance P and other mammalian neurokinins].
Topics: Animals; Brain; Cattle; Humans; Neurokinin A; Neurokinin B; Neuropeptides; Protein Biosynthesis; Rats; Spinal Cord; Substance P; Swine; Transcription, Genetic | 1992 |
Neurokinin A and B.
Topics: Amino Acid Sequence; Animals; Humans; Molecular Sequence Data; Neurokinin A; Neurokinin B; Structure-Activity Relationship; Substance P; Tissue Distribution | 1991 |
Pharmacological and biochemical evidence for multiple types of tachykinin NK2 receptors.
Topics: Animals; Molecular Weight; Neurokinin A; Neurokinin B; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins | 1991 |
Effects of various tachykinins on pituitary LH secretion, feeding, and sexual behavior in the rat.
Topics: Animals; Feeding Behavior; Female; Luteinizing Hormone; Male; Neurokinin A; Neurokinin B; Neuropeptides; Pituitary Gland, Anterior; Rats; Sexual Behavior, Animal; Substance P; Tachykinins | 1991 |
Molecular characterization of the three tachykinin receptors.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Molecular Sequence Data; Neurokinin A; Neurokinin B; Protein Conformation; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Neurotransmitter; Sequence Homology, Nucleic Acid; Substance P; Tachykinins | 1991 |
[Recent advances in research on substance P and related neuropeptides].
Topics: Amino Acid Sequence; Animals; Base Sequence; Cats; Central Nervous System; Guinea Pigs; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Neurons; Neurotransmitter Agents; Oligopeptides; Rats; Substance P | 1985 |
Pharmacological receptors for substance P and neurokinins.
Topics: Animals; Dogs; Guinea Pigs; Neurokinin A; Neurokinin B; Neuropeptides; Rabbits; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Structure-Activity Relationship; Substance P | 1987 |
Peptides as neuromodulators in primary sensory neurons.
Topics: Amino Acid Sequence; Animals; Calcitonin Gene-Related Peptide; Neurokinin A; Neurokinin B; Neurons, Afferent; Neuropeptides; Neurotransmitter Agents; Substance P | 1987 |
Substance P antagonists and analgesia: a review of the hypothesis.
Topics: Amino Acid Sequence; Analgesics; Animals; Molecular Sequence Data; Neurokinin A; Neurokinin B; Species Specificity; Substance P | 1988 |
Are the proposed substance P receptor sub-types, substance P receptors?
Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Eledoisin; Hydrolysis; Kassinin; Muscle Contraction; Neurokinin B; Oligopeptides; Peptide Fragments; Phospholipids; Physalaemin; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Structure-Activity Relationship; Substance P | 1984 |
Species variants of tachykinin receptor types.
Topics: Amino Acid Sequence; Animals; Brain; Cattle; Cricetinae; Guinea Pigs; Kinetics; Molecular Sequence Data; Neurokinin A; Neurokinin B; Rabbits; Radioligand Assay; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Sequence Homology, Amino Acid; Species Specificity; Substance P; Urinary Bladder | 1994 |
Peptide-based tachykinin NK2 receptor antagonists.
Topics: Animals; Dipeptides; Humans; Neurokinin A; Neurokinin B; Oligopeptides; Peptide Fragments; Peptides; Peptides, Cyclic; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P | 1995 |
Neurokinin mediation of edema and inflammation.
Topics: Animals; Edema; Humans; Inflammation; Neurokinin A; Neurokinin B; Substance P; Tachykinins | 2000 |
The role of tachykinins in central nervous system inflammatory responses.
Topics: Animals; Astrocytes; Central Nervous System; Humans; Inflammation; Microglia; Neurokinin A; Neurokinin B; Neurons; Oligodendroglia; Substance P; Tachykinins | 2004 |
Non-neuronal mammalian tachykinin expression.
Topics: Animals; Gene Expression Regulation; Ligands; Neurokinin A; Neurokinin B; Peptides; Physalaemin; Protein Binding; Receptors, Neurokinin-1; Substance P; Tachykinins | 2004 |
Selective and combined neurokinin receptor antagonists.
Topics: Animals; Central Nervous System Diseases; Drug Combinations; Gastrointestinal Diseases; Humans; Lung Diseases; Neurokinin A; Neurokinin B; Pain; Receptors, Tachykinin; Substance P; Urologic Diseases; Vomiting | 2005 |
Tachykinin receptors antagonism for asthma: a systematic review.
Topics: Anti-Asthmatic Agents; Asthma; Humans; Neurokinin A; Neurokinin B; Receptors, Tachykinin; Substance P; Treatment Outcome | 2011 |
Tachykinin NK
Topics: Humans; Neurokinin A; Neurokinin B; Receptors, Neurokinin-2; Substance P; Tachykinins | 2021 |
1 trial(s) available for substance p and neurokinin b
| Article | Year |
|---|---|
Localization of neurons expressing substance P and neurokinin B gene transcripts in the human hypothalamus and basal forebrain.
Topics: Adolescent; Adult; Amygdala; Corpus Striatum; Gene Expression Regulation; Humans; Hypothalamus; In Situ Hybridization; Male; Mammillary Bodies; Middle Aged; Neurokinin B; Neurons; Oligonucleotide Probes; Optic Chiasm; Prosencephalon; Substance P | 1997 |
377 other study(ies) available for substance p and neurokinin b
| Article | Year |
|---|---|
A new class of high affinity ligands for the neurokinin A NK2 receptor: psi (CH2NR) reduced peptide bond analogues of neurokinin A4-10.
Topics: Amino Acid Sequence; Animals; Cricetinae; In Vitro Techniques; Ligands; Molecular Sequence Data; Neurokinin A; Oxidation-Reduction; Peptide Fragments; Phosphatidylinositols; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Urinary Bladder | 1992 |
Conformationally constrained tachykinin analogues: potent and highly selective neurokinin NK-2 receptor agonists.
Topics: Amino Acid Sequence; Animals; Guinea Pigs; In Vitro Techniques; Lactams; Male; Models, Molecular; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Protein Conformation; Rats; Receptors, Neurotransmitter; Receptors, Tachykinin; Stereoisomerism; Structure-Activity Relationship; Tachykinins | 1992 |
Characterization of the binding sites of [3H]SR 48968, a potent nonpeptide radioligand antagonist of the neurokinin-2 receptor.
Topics: Animals; Benzamides; Binding Sites; Binding, Competitive; Cricetinae; Duodenum; Guinea Pigs; In Vitro Techniques; Kinetics; Mesocricetus; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Urinary Bladder | 1993 |
Nonpeptide tachykinin receptor antagonists: I. Pharmacological and pharmacokinetic characterization of SB 223412, a novel, potent and selective neurokinin-3 receptor antagonist.
Topics: Animals; Calcium; CHO Cells; Cricetinae; Dogs; Humans; Mice; Piperidines; Quinolines; Rabbits; Radioligand Assay; Rats; Receptors, Neurokinin-3; Receptors, Tachykinin | 1997 |
High affinity, selective neurokinin 2 and neurokinin 3 receptor antagonists from a common structural template.
Topics: Animals; Calcium; CHO Cells; Cricetinae; Fluorescent Dyes; Fura-2; Humans; Lactams; Molecular Conformation; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Spectrometry, Fluorescence; Structure-Activity Relationship | 1998 |
Importance of the aromatic residue at position 6 of [Nle(10)]neurokinin A(4-10) for binding to the NK-2 receptor and receptor activation.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Humans; In Vitro Techniques; Male; Mesocricetus; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Receptors, Neurokinin-2; Structure-Activity Relationship; Trachea | 1999 |
Molecular and pharmacological characterization of the murine tachykinin NK(3) receptor.
Topics: Amino Acid Sequence; Animals; Calcium; Cloning, Molecular; Humans; Mice; Molecular Sequence Data; Neurokinin A; Quinolines; Receptors, Neurokinin-3 | 2001 |
Activation of an epithelial neurokinin NK-1 receptor induces relaxation of rat trachea through release of prostaglandin E2.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Binding Sites; Biological Factors; Dinoprost; Dinoprostone; Epithelium; Indomethacin; Male; Muscle Relaxation; Neurokinin B; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Thromboxane B2; Time Factors; Trachea | 1992 |
Limbic seizures cause pronounced changes in the expression of neurokinin B in the hippocampus of the rat.
Topics: Animals; Hippocampus; Immunohistochemistry; Kainic Acid; Limbic System; Male; Neurokinin B; Nucleic Acid Hybridization; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures; Substance P; Tachykinins | 1992 |
Substance P opens cation channels and closes potassium channels in rat locus coeruleus neurons.
Topics: Animals; Calcium; Cations; Chlorides; In Vitro Techniques; Ion Channel Gating; Ion Channels; Locus Coeruleus; Magnesium; Membrane Potentials; Neurokinin A; Neurokinin B; Neurons; Potassium; Potassium Channels; Rats; Substance P; Tetrodotoxin | 1992 |
Neurokinin3 receptor regulation of acetylcholine release from myenteric plexus.
Topics: Acetylcholine; Animals; Calcium; Calcium Channel Blockers; Enzyme Activation; Guinea Pigs; In Vitro Techniques; Myenteric Plexus; Neurokinin B; Peptide Fragments; Protein Kinase C; Receptors, Neurokinin-3; Receptors, Neurotransmitter; Substance P; Tetrodotoxin | 1992 |
The extracellular domain of the neurokinin-1 receptor is required for high-affinity binding of peptides.
Topics: Amino Acid Sequence; Animals; Cell Line; Glutamates; Glutamic Acid; Glycosylation; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurokinin A; Neurokinin B; Rats; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Structure-Activity Relationship; Substance P; Transfection; Valine | 1992 |
Role of tachykinins in the control of pancreatic secretion and circulation.
Topics: Amino Acid Sequence; Amylases; Anesthesia; Animals; Dogs; Dose-Response Relationship, Drug; Male; Molecular Sequence Data; Neurokinin A; Neurokinin B; Oxygen Consumption; Pancreas; Pancreatic Hormones; Rats; Rats, Wistar; Regional Blood Flow; Stimulation, Chemical; Substance P; Tachykinins | 1992 |
Distinct presynaptic control of dopamine release in striosomal- and matrix-enriched areas of the rat striatum by selective agonists of NK1, NK2, and NK3 tachykinin receptors.
Topics: Animals; Atropine; Corpus Striatum; Dopamine; Male; Neurokinin A; Neurokinin B; Pempidine; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Synaptic Membranes; Synaptic Transmission; Tetrodotoxin | 1992 |
Localization of agonist and antagonist binding domains of the human neurokinin-1 receptor.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Membrane; Chlorides; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurokinin A; Neurokinin B; Oocytes; Polymerase Chain Reaction; Protein Conformation; Quinuclidines; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Recombinant Proteins; Substance P; Xenopus | 1992 |
Comparative distribution of neurokinin B-, substance P- and enkephalin-like immunoreactivities and neurokinin B messenger RNA in the basal forebrain of the rat: evidence for neurochemical compartmentation.
Topics: Animals; Basal Ganglia; Enkephalins; Immunoenzyme Techniques; Immunohistochemistry; In Situ Hybridization; Male; Neurokinin B; Organ Specificity; Prosencephalon; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P | 1992 |
Characterization of NK-1 receptors in guinea pig and rat brain membranes with NK-1 peptides and a non-peptide antagonist.
Topics: Amino Acid Sequence; Animals; Biphenyl Compounds; Brain; Guinea Pigs; Membranes; Molecular Sequence Data; Neurokinin A; Neurokinin B; Rats; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1992 |
A pharmacological study of NK1 and NK2 tachykinin receptor characteristics in the rat isolated urinary bladder.
Topics: Animals; Carbachol; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Rats; Rats, Wistar; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Urinary Bladder | 1992 |
The motor actions of natural neurokinins and their specific agonists on the gastrointestinal tract of the rat.
Topics: Animals; Charcoal; Gastrointestinal Motility; Injections, Intraperitoneal; Male; Neurokinin A; Neurokinin B; Peptide Fragments; Pilot Projects; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Tachykinins | 1992 |
Postnatal changes in the substance P receptor on rabbit gastric smooth muscle.
Topics: Aging; Animals; Animals, Newborn; Binding, Competitive; Dose-Response Relationship, Drug; Gastric Mucosa; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Osmolar Concentration; Rabbits; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Stomach; Substance P; Tachykinins; Time Factors | 1992 |
Cortisol secretion induced by substance P from bovine adrenocortical cells and its inhibition by calmodulin inhibitors.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Calcium; Calmodulin; Cattle; Cyclic AMP; Dose-Response Relationship, Drug; Hydrocortisone; Imidazoles; Neurokinin A; Neurokinin B; Signal Transduction; Substance P; Sulfonamides; Trifluoperazine | 1992 |
Distribution of neurons expressing neurokinin B in the rat brain: immunohistochemistry and in situ hybridization.
Topics: Amino Acid Sequence; Animals; Brain; Cerebral Cortex; Immunohistochemistry; Male; Molecular Sequence Data; Neurokinin B; Neurons; Nucleic Acid Hybridization; Olfactory Bulb; Rabbits; Rats; Rats, Inbred Strains; RNA, Messenger; Substance P; Telencephalon | 1992 |
Molecular cloning of substance P receptor cDNA from guinea-pig uterus.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA, Recombinant; Female; Guinea Pigs; Molecular Sequence Data; Neurokinin A; Neurokinin B; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Uterus | 1992 |
Neurokinin receptors and mucosal ion transport in porcine jejunum.
Topics: Animals; Autoradiography; Binding Sites; Biological Transport, Active; Female; Intestinal Mucosa; Jejunum; Male; Muscle Contraction; Neurokinin A; Neurokinin B; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Succinimides; Swine | 1992 |
Distribution of neurokinin B in rat spinal cord and peripheral tissues: comparison with neurokinin A and substance P and effects of neonatal capsaicin treatment.
Topics: Animals; Animals, Newborn; Capsaicin; Ganglia, Spinal; Guinea Pigs; Male; Neurokinin A; Neurokinin B; Organ Specificity; Radioimmunoassay; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Cord; Substance P | 1992 |
CGRP modulates nerve-mediated vasoconstriction of rat knee joint blood vessels.
Topics: Animals; Arteries; Calcitonin Gene-Related Peptide; Electric Stimulation; Humans; Joints; Male; Muscle, Smooth, Vascular; Nerve Fibers; Neurokinin A; Neurokinin B; Neuropeptides; Peripheral Nerves; Rats; Rats, Inbred Strains; Regional Blood Flow; Substance P; Vasoconstriction; Vasodilation | 1992 |
Differences in neurokinin receptor pharmacology between rat and guinea-pig superior cervical ganglia.
Topics: Animals; Ganglia, Sympathetic; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Neurokinin A; Neurokinin B; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Species Specificity; Substance P | 1992 |
Diverse effects of tachykinins on luteinizing hormone release in male rats: mechanism of action.
Topics: Animals; Cerebral Ventricles; Dose-Response Relationship, Drug; Injections, Intraventricular; Luteinizing Hormone; Male; Neurokinin A; Neurokinin B; Neuropeptides; Orchiectomy; Peptide Fragments; Rats; Rats, Inbred Strains; Reference Values; Substance P; Tachykinins | 1992 |
Bronchial epithelial cells release neutrophil chemotactic activity in response to tachykinins.
Topics: Animals; Bronchi; Epithelial Cells; Epithelium; Interleukin-8; Neprilysin; Neurokinin A; Neurokinin B; Peptide Fragments; Protease Inhibitors; Substance P; Tachykinins | 1992 |
Tachykinins preferentially excite certain complex cells in the infragranular layers of feline striate cortex.
Topics: Animals; Cats; Evoked Potentials, Visual; Female; Iontophoresis; Male; Neurokinin A; Neurokinin B; Neurons; Peptide Fragments; Substance P; Tachykinins; Visual Cortex | 1992 |
Fast and slow depolarizations produced by substance P and other tachykinins in sympathetic neurons of rat prevertebral ganglia.
Topics: Animals; Chromatography, High Pressure Liquid; Electrophysiology; Ganglia, Sympathetic; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Neuromuscular Depolarizing Agents; Neurons; Radioimmunoassay; Rats; Substance P; Tachykinins; Temperature | 1992 |
Receptors for neurokinins in human bronchus and urinary bladder are of the NK-2 type.
Topics: Bronchi; Humans; In Vitro Techniques; Middle Aged; Muscle, Smooth; Neurokinin A; Neurokinin B; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Urinary Bladder | 1990 |
Potent and highly selective neurokinin antagonists.
Topics: Amino Acid Sequence; Animals; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Intestines; Molecular Sequence Data; Molecular Structure; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Protein Conformation; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Neurotransmitter; Structure-Activity Relationship; Substance P | 1990 |
[Stimulation of mucous glands of the respiratory tract by neuropeptides: comparison of exogenous administration and endogenous liberation].
Topics: Animals; Exocrine Glands; Female; Ferrets; Male; Mucus; Neurokinin A; Neurokinin B; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Trachea | 1990 |
[Localization and physiologic role of neuropeptides and their receptors--the tachykinin family of substance P, neurokinin A and neurokinin B].
Topics: Amino Acid Sequence; Animals; Binding Sites; Molecular Sequence Data; Nervous System; Neurokinin A; Neurokinin B; Neurotransmitter Agents; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P | 1990 |
Inhibitors of peptidases: how they influence the biological activities of substance P, neurokinins, kinins and angiotensins in isolated vessels.
Topics: Angiotensin II; Animals; Captopril; Carotid Arteries; Dogs; Female; In Vitro Techniques; Kinins; Leucine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Portal Vein; Protease Inhibitors; Pulmonary Artery; Rabbits; Rats; Rats, Inbred Strains; Substance P | 1990 |
Inhibitors of peptidases: how they influence the biological activities of substance P, neurokinins, bradykinin and angiotensin in guinea pig, hamster and rat urinary bladders.
Topics: Angiotensin II; Animals; Cricetinae; Female; Guinea Pigs; In Vitro Techniques; Kinins; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Protease Inhibitors; Rats; Rats, Inbred Strains; Substance P; Urinary Bladder | 1990 |
Tachykinins activate guinea-pig alveolar macrophages: involvement of NK2 and NK1 receptors.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Macrophage Activation; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Neurokinin A; Neurokinin B; Pulmonary Alveoli; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Neurotransmitter; Substance P; Superoxides; Tachykinins | 1990 |
Pharmacological profile of a tachykinin antagonist, spantide, as examined on rat spinal motoneurones.
Topics: Analgesics; Animals; Animals, Newborn; Motor Neurons; Neurokinin A; Neurokinin B; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Spinal Cord; Substance P; Tachykinins; Tetrodotoxin | 1990 |
Studies on the vascular permeability induced by intrathecal substance P and bradykinin in the rat.
Topics: Adrenalectomy; Animals; Blood Proteins; Bradykinin; Capillary Permeability; Capsaicin; Decerebrate State; In Vitro Techniques; Injections, Spinal; Male; Neurokinin A; Neurokinin B; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Vagotomy | 1990 |
Occurrence, release, and effects of multiple tachykinins in cat colonic tissues and nerves.
Topics: Animals; Cats; Chromatography, High Pressure Liquid; Colon; Electric Stimulation; Eledoisin; Female; Ganglia, Autonomic; Male; Muscle Contraction; Neurokinin A; Neurokinin B; Physalaemin; Physical Stimulation; Radioimmunoassay; Substance P; Tachykinins; Vasodilation | 1991 |
Neurokinin-immunoreactivity in human neuroblastomas. Evidence for selective expression of the preprotachykinin (PPT) II gene.
Topics: Chromatography, High Pressure Liquid; Gene Expression; Humans; Neuroblastoma; Neurokinin A; Neurokinin B; Protein Precursors; Radioimmunoassay; Substance P; Tachykinins | 1990 |
Enzyme immunoassay for tachykinin-like immunoreactivity in the guinea pig spinal cord.
Topics: Acetylcholinesterase; Animals; Capsaicin; Eledoisin; Guinea Pigs; Immunoenzyme Techniques; Kassinin; Male; Neurokinin A; Neurokinin B; Physalaemin; Potassium; Radioimmunoassay; Spinal Cord; Substance P; Tachykinins; Thiorphan | 1991 |
Tachykinins in the canine gastroesophageal junction.
Topics: Animals; Atropine; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Esophagogastric Junction; Esophagus; Gastric Mucosa; Immunohistochemistry; Manometry; Muscle Contraction; Neurokinin A; Neurokinin B; Neurons; Phentolamine; Radioimmunoassay; Substance P; Tachykinins; Tetrodotoxin | 1991 |
Priming effects of mammalian tachykinins on human neutrophils.
Topics: Dose-Response Relationship, Drug; Humans; Neurokinin A; Neurokinin B; Neutrophils; Platelet Activating Factor; Stimulation, Chemical; Substance P; Superoxides; Tachykinins | 1991 |
Tachykinins stimulate lyso-PAF:acetyl-CoA acetyltransferase activity in neutrophils.
Topics: Acetyltransferases; Animals; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Phenylalanine; Neurokinin A; Neurokinin B; Neutrophils; Rats; Rats, Inbred Strains; Stimulation, Chemical; Substance P; Tachykinins | 1990 |
Central action of tachykinins on activity of expiratory pumping muscles.
Topics: Animals; Cats; Dogs; Electromyography; Electrophysiology; Female; Injections; Male; Medulla Oblongata; Neurokinin A; Neurokinin B; Respiratory Muscles; Substance P; Tachykinins | 1990 |
Characterization of tachykinin receptors in urinary bladder from guinea pig.
Topics: Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; Muscle Contraction; Neurokinin A; Neurokinin B; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Urinary Bladder | 1990 |
Characterisation of the neurokinin receptors mediating contraction of isolated tracheal preparations from a variety of species.
Topics: Animals; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Neurokinin A; Neurokinin B; Peptide Fragments; Rabbits; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Neurotransmitter; Substance P; Swine; Trachea | 1990 |
Novel selective agonists and antagonists confirm neurokinin NK1 receptors in guinea-pig vas deferens.
Topics: Animals; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Neurokinin A; Neurokinin B; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Tachykinins; Vas Deferens | 1991 |
Gastrin-releasing peptide is a transmitter mediating porcine gallbladder contraction.
Topics: Animals; Atropine; Carbachol; Electric Stimulation; Gallbladder; Gastrin-Releasing Peptide; Gastrointestinal Hormones; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth; Nerve Fibers; Neurokinin B; Peptides; Sincalide; Substance P; Swine; Tetrodotoxin | 1991 |
Hypertrophy and increased gene expression of neurons containing neurokinin-B and substance-P messenger ribonucleic acids in the hypothalami of postmenopausal women.
Topics: Adolescent; Adult; Aged; Cell Count; Female; Gene Expression Regulation; Humans; Hypertrophy; Hypothalamus; Menopause; Middle Aged; Neurokinin B; Neurons; Receptors, Estrogen; RNA, Messenger; Substance P | 1991 |
Hypothalamic regulatory peptides in obese and lean Zucker rats.
Topics: Animals; Bombesin; Calcitonin Gene-Related Peptide; Food Deprivation; Galanin; Hypothalamus; Hypothalamus, Middle; Neurokinin B; Neuropeptide Y; Neuropeptides; Neurotensin; Obesity; Peptides; Radioimmunoassay; Rats; Rats, Zucker; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1991 |
Localization and characterization of substance P binding sites in rat and rabbit eyes.
Topics: Animals; Autoradiography; Binding Sites; Eye; Kinetics; Neurokinin B; Rabbits; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P | 1991 |
Tachykinin immunoreactivity in the European common frog, Rana temporaria: localization, quantification and chromatographic characterization.
Topics: Amino Acid Sequence; Animals; Brain Chemistry; Chromatography, Gel; Chromatography, High Pressure Liquid; Fluorescent Antibody Technique; Intestines; Molecular Sequence Data; Nerve Fibers; Neurokinin B; Radioimmunoassay; Rana temporaria; Skin; Stomach; Substance P; Tachykinins; Tissue Distribution | 1990 |
Smooth muscle of rabbit isolated aorta contains the NK-2 tachykinin receptor.
Topics: Animals; Aorta, Thoracic; Female; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Rabbits; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P | 1990 |
Opioid and neurokinin activities of substance P fragments and their analogs.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Neurokinin A; Neurokinin B; Peptide Fragments; Premedication; Substance P | 1991 |
Tachykinins (substance P, neurokinin A, neuropeptide K, and neurokinin B) in the cerebral circulation: vasomotor responses in vitro and in situ.
Topics: Animals; Arterioles; Basilar Artery; Binding, Competitive; Cats; Cerebral Arteries; Cerebrovascular Circulation; Endothelium, Vascular; Guinea Pigs; Humans; Neurokinin A; Neurokinin B; Neuropeptides; Pia Mater; Substance P; Tachykinins; Vasodilation | 1991 |
Characterization of NK-3 binding sites in rat and guinea pig cortical membranes by the selective ligand [3H]Senktide.
Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Cell Membrane; Cerebral Cortex; Guinea Pigs; Kinetics; Ligands; Male; Molecular Sequence Data; Neurokinin B; Neuropeptides; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Neurokinin-3; Receptors, Neurotransmitter; Substance P | 1991 |
Tachykinins in the rat substantia nigra: effects of selective dopamine receptor antagonists.
Topics: Amino Acid Sequence; Animals; Benzazepines; Chromatography, High Pressure Liquid; Dopamine Antagonists; Haloperidol; Male; Molecular Sequence Data; Neurokinin B; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra; Sulpiride; Tachykinins | 1991 |
The effects of neurokinin A, neurokinin B, and eledoisin on substance P analysis.
Topics: Angina Pectoris; Back Pain; Carcinoid Tumor; Eledoisin; Humans; Neurokinin A; Neurokinin B; Pericardial Effusion; Protein Binding; Saliva; Species Specificity; Substance P | 1991 |
Capsaicin and sensory neuropeptide stimulation of goblet cell secretion in guinea-pig trachea.
Topics: Anesthesia, General; Animals; Axons; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Exocrine Glands; Guinea Pigs; Male; Mucus; Neurokinin A; Neurokinin B; Neuropeptides; Substance P; Time Factors; Trachea | 1990 |
Effects of intranigral substance P and neurokinin A injections on extracellular dopamine levels measured with microdialysis in the striatum and frontoparietal cortex of rats.
Topics: Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dopamine; Injections, Intraventricular; Injections, Subcutaneous; Male; Neurokinin B; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra | 1991 |
The tachykinin NH2-senktide inhibits alcohol intake in alcohol-preferring rats.
Topics: Alcohol Drinking; Animals; Captopril; Dose-Response Relationship, Drug; Drinking; Injections, Intraventricular; Male; Neurokinin B; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Neurokinin-3; Receptors, Neurotransmitter; Substance P | 1991 |
Contrasting effects of tachykinins and guanethidine on the acetylcholine output stimulated by nicotine from guinea-pig bladder [corrected].
Topics: Acetylcholine; Analgesics; Animals; Atropine; Female; Guanethidine; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Neurokinin B; Nicotine; Radioimmunoassay; Substance P; Sulfones; Sympathetic Nervous System; Tachykinins; Urinary Bladder | 1991 |
Specific neurokinin receptors mediate plasma extravasation in the rat knee joint.
Topics: Animals; Calcitonin Gene-Related Peptide; Cartilage, Articular; Injections; Knee Joint; Male; Neurokinin A; Neurokinin B; Neuropeptides; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1991 |
Tachykinin antagonists and capsaicin-induced contraction of the rat isolated urinary bladder: evidence for tachykinin-mediated cotransmission.
Topics: Adenosine Triphosphate; Animals; Bombesin; Capsaicin; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Rats; Rats, Inbred Strains; Receptors, Purinergic; Substance P; Synaptic Transmission; Tachykinins; Urinary Bladder | 1991 |
Clinical and inflammatory responses to exogenous tachykinins in allergic rhinitis.
Topics: Adult; Airway Resistance; Dose-Response Relationship, Drug; Eosinophils; Female; Flushing; Hemodynamics; Histamine; Humans; Male; Nasal Mucosa; Nasal Provocation Tests; Neurokinin B; Neutrophils; Peptide Fragments; Proteins; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Substance P; Tachykinins | 1991 |
Neurokinin receptors antagonists: old and new.
Topics: Amino Acid Sequence; Analgesics; Animals; Dogs; Guinea Pigs; Kinetics; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Peptide Fragments; Rabbits; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1991 |
Receptor-selective, peptidase-resistant agonists at neurokinin NK-1 and NK-2 receptors: new tools for investigating neurokinin function.
Topics: Administration, Cutaneous; Amino Acid Sequence; Animals; Bronchoconstriction; Capillary Permeability; Chromatography, High Pressure Liquid; Guinea Pigs; Male; Molecular Sequence Data; Neurokinin A; Neurokinin B; Peptide Fragments; Rats; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Trachea | 1991 |
Multiple neurokinin receptor subtypes are present in the colon of the cat and rat.
Topics: Animals; Atropine; Cats; Colon; In Vitro Techniques; Isometric Contraction; Muscle, Smooth; Neurokinin B; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tetrodotoxin | 1991 |
Novel ligands confirm NK-1 receptor-mediated modulation of neurotransmission in the guinea pig vas deferens preparation.
Topics: Animals; Electric Stimulation; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Synaptic Transmission; Vas Deferens | 1991 |
Neurokinin innervation of the rat median raphe nucleus does not originate in the brain stem.
Topics: Animals; Axonal Transport; Brain Stem; Chromatography, High Pressure Liquid; Fluorescent Dyes; Male; Neurokinin A; Neurokinin B; Radioimmunoassay; Raphe Nuclei; Rats; Rats, Inbred Strains; Stilbamidines; Substance P | 1991 |
Studies of reflexogenic effects of capsaicin and neuropeptides on neural afferents in the dog parietal pericardium.
Topics: Afferent Pathways; Animals; Arachidonic Acid; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Denervation; Dogs; Female; Heart Rate; Male; Neurokinin A; Neurokinin B; Neuropeptides; Pentolinium Tartrate; Pericardium; Propranolol; Substance P | 1991 |
Substance P-evoked release of acetylcholine from isolated spinal cord of the newborn rat.
Topics: Acetylcholine; Animals; Animals, Newborn; Calcium; Dihydro-beta-Erythroidine; Edrophonium; Neurokinin A; Neurokinin B; Peptide Fragments; Physostigmine; Potassium; Rats; Rats, Inbred Strains; Secretory Rate; Spinal Cord; Stimulation, Chemical; Substance P; Tetrodotoxin; Veratridine | 1991 |
The effect of selective serotonergic neurotoxin treatment on tachykinin levels in the rat ventral spinal cord.
Topics: 5,7-Dihydroxytryptamine; Animals; Chromatography, High Pressure Liquid; Gene Expression Regulation; Male; Neurokinin A; Neurokinin B; Neuropeptides; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Substance P; Tachykinins | 1991 |
Neurokinins produce selective venoconstriction via NK-3 receptors in the rat mesenteric vascular bed.
Topics: Acetylcholine; Animals; Bradykinin; Cholic Acids; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Perfusion; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Tachykinin; Splanchnic Circulation; Structure-Activity Relationship; Substance P; Vasoconstriction; Vasodilation | 1991 |
Effects of tachykinins on myenteric neurones of the guinea-pig gastric corpus: involvement of NK-3 receptors.
Topics: Animals; Electrophysiology; Guinea Pigs; In Vitro Techniques; Myenteric Plexus; Neurokinin A; Neurokinin B; Neurons; Receptors, Neurotransmitter; Receptors, Tachykinin; Stomach; Substance P; Tachykinins | 1991 |
Involvement of NK1 receptors and importance of the N-terminal sequence of substance P in the stimulation of protein secretion in rat parotid glands.
Topics: Amino Acid Sequence; Animals; Male; Molecular Sequence Data; Neurokinin A; Neurokinin B; Parotid Gland; Proteins; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Tachykinin; Stimulation, Chemical; Substance P | 1991 |
Neuropeptide K: a major tachykinin in plasma and tumor tissues from carcinoid patients.
Topics: Carcinoid Tumor; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Eledoisin; Humans; Immunoassay; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Substance P; Tachykinins | 1985 |
The regional distribution of kassinin-like immunoreactivity in central and peripheral tissues of the cat.
Topics: Adrenal Glands; Animals; Cats; Central Nervous System; Chromatography, High Pressure Liquid; Digestive System; Ganglia, Spinal; Ganglia, Sympathetic; Kassinin; Male; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Radioimmunoassay; Substance P; Tissue Distribution | 1985 |
Potentiation of tachykinin-induced plasma protein extravasation by calcitonin gene-related peptide.
Topics: Animals; Blood Proteins; Calcitonin Gene-Related Peptide; Drug Synergism; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Neuropeptide Y; Oligopeptides; Rats; Substance P; Tachykinins | 1985 |
In vivo and in vitro actions of mammalian tachykinins.
Topics: Animals; Blood Pressure; Eledoisin; Female; Guinea Pigs; Hindlimb; Histamine Release; Ileum; In Vitro Techniques; Jejunum; Kassinin; Male; Muscle Contraction; Muscle, Smooth; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Rabbits; Rats; Rats, Inbred Strains; Salivation; Substance P; Tachykinins; Vas Deferens; Vasodilation | 1985 |
Receptors for mammalian tachykinins on isolated intestinal smooth muscle cells.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Intestines; Muscle Contraction; Muscle, Smooth; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P | 1985 |
Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin.
Topics: Animals; Atropine; Enkephalin, Methionine; Guinea Pigs; Ileum; Muscle Contraction; Muscle, Smooth; Naloxone; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Neurons; Neurotransmitter Agents; Oligopeptides; Peptide Fragments; Receptors, Muscarinic; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Substrate Specificity; Tachykinins | 1985 |
Regional distribution of substance P, neurokinin alpha and neurokinin beta in rat spinal cord, nerve roots and dorsal root ganglia, and the effects of dorsal root section or spinal transection.
Topics: Animals; Central Nervous System; Ganglia, Spinal; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Rats; Rats, Inbred Strains; Spinal Cord; Spinal Nerve Roots; Spinal Nerves; Substance P | 1985 |
Substance K, a novel tachykinin injected bilaterally into the ventral tegmental area of rats increases behavioral response.
Topics: Animals; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Male; Motor Activity; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Rats; Rats, Inbred Strains; Substance P; Tegmentum Mesencephali; Time Factors | 1985 |
The contractile activities of neurokinin A, B and related peptides on smooth muscles.
Topics: Amino Acid Sequence; Animals; Duodenum; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Rats; Structure-Activity Relationship; Substance P; Vas Deferens | 1986 |
Tachykinin modulation of coronary blood flow.
Topics: Animals; Coronary Circulation; Female; Hemodynamics; Male; Myocardial Contraction; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Substance P; Swine; Tachykinins | 1986 |
"Kassinin" in mammals: the newest tachykinins.
Topics: Amino Acid Sequence; Animals; Kassinin; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Radioimmunoassay; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins; Tissue Distribution | 1985 |
Histamine release and local responses of rat and human skin to substance P and other mammalian tachykinins.
Topics: Animals; Capillary Permeability; Histamine Release; Humans; In Vitro Techniques; Kassinin; Kinins; Mast Cells; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Rats; Rats, Inbred Strains; Skin; Skin Tests; Structure-Activity Relationship; Substance P | 1986 |
Different receptors are involved in the endothelium-mediated relaxation and the smooth muscle contraction of the rabbit pulmonary artery in response to substance P and related neurokinins.
Topics: Animals; Endothelium; In Vitro Techniques; Kassinin; Kinins; Muscle, Smooth, Vascular; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Pulmonary Artery; Rabbits; Receptors, Bradykinin; Receptors, Neurotransmitter; Substance P | 1986 |
Specific recognition of SP or NKB receptors by analogues of SP substituted at positions 8 and 9.
Topics: Animals; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neurokinin B; Oligopeptides; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P | 1986 |
Stimulatory effect of substance P on the spontaneous release of newly synthesized [3H]dopamine from rat striatal slices: a tetrodotoxin-sensitive process.
Topics: Acetylcholine; Animals; Corpus Striatum; Dopamine; Drug Synergism; Male; Neurokinin B; Neuropeptides; Rats; Rats, Inbred Strains; Recombinant Proteins; Substance P; Tetrodotoxin | 1986 |
Differentiation of multiple neurokinin receptors in the guinea pig ileum.
Topics: Animals; Atropine; Binding, Competitive; Guinea Pigs; Ileum; Male; Muscle Contraction; Neurokinin A; Neurokinin B; Neuropeptides; Peptide Fragments; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1986 |
A cyclic analogue selective for the NKB specific binding site on rat brain synaptosomes.
Topics: Animals; Brain Chemistry; Guinea Pigs; In Vitro Techniques; Iodine Radioisotopes; Muscle, Smooth; Neurokinin B; Peptides, Cyclic; Substance P; Synaptosomes | 1986 |
Levels of neurokinin A, neurokinin B and substance P in rabbit iris sphincter muscle.
Topics: Animals; Female; Iris; Male; Muscle, Smooth; Neurokinin A; Neurokinin B; Neuropeptides; Protein Precursors; Rabbits; RNA, Messenger; Substance P; Tachykinins | 1986 |
Tachykinin regulation of serotonin release: enhancement of [3H]serotonin release from rat cerebral cortex by neuromedin K and substance P acting at distinct receptor sites.
Topics: Animals; Cerebral Cortex; Drug Synergism; Male; Neurokinin B; Neuropeptides; Potassium; Rats; Rats, Inbred Strains; Serotonin; Substance P | 1987 |
Regional distribution of neuropeptide K and other tachykinins (neurokinin A, neurokinin B and substance P) in rat central nervous system.
Topics: Animals; Antibodies; Antibody Specificity; Central Nervous System; Chromatography, High Pressure Liquid; Male; Neurokinin A; Neurokinin B; Neuropeptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P; Tachykinins | 1986 |
Pilocarpine-induced reciprocal hindlimb scratching in mice.
Topics: Animals; Cerebral Ventricles; Injections, Intraventricular; Male; Methysergide; Mice; Naloxone; Neurokinin B; Neuropeptides; Peptide Fragments; Phentolamine; Pilocarpine; Stereotyped Behavior; Substance P; Yohimbine | 1987 |
Pharmacological evidence for the possible coexistence of multiple receptor sites for mammalian tachykinins in rabbit iris sphincter smooth muscle.
Topics: Animals; Carbachol; Eledoisin; In Vitro Techniques; Iris; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Neuropeptides; Rabbits; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tetrodotoxin | 1987 |
Action of the newly discovered mammalian tachykinins, substance K and neuromedin K, on gastroduodenal motility of anesthetized dogs.
Topics: Animals; Dogs; Duodenum; Eledoisin; Gastrointestinal Motility; Muscle Contraction; Neurokinin A; Neurokinin B; Neuropeptides; Physalaemin; Stomach; Substance P; Tachykinins | 1987 |
Further studies on the mechanisms of the tachykinin-induced activation of micturition reflex in rats: evidence for the involvement of the capsaicin-sensitive bladder mechanoreceptors.
Topics: Aging; Animals; Capsaicin; Diphenhydramine; Electric Stimulation; In Vitro Techniques; Indomethacin; Kassinin; Male; Mechanoreceptors; Neurokinin A; Neurokinin B; Neuropeptides; Oligopeptides; Rats; Rats, Inbred Strains; Substance P; Tetrodotoxin; Urinary Bladder; Urination | 1987 |
Effects of subchronic treatment with imipramine, zimelidine and alaproclate on regional tissue levels of substance P- and neurokinin A/neurokinin B-like immunoreactivity in the brain and spinal cord of the rat.
Topics: Alanine; Animals; Antidepressive Agents; Brain Chemistry; Central Nervous System; Imipramine; Immune Sera; Male; Neurokinin A; Neurokinin B; Neuropeptides; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Zimeldine | 1987 |
Pharmacological analysis of 125I-Bolton and Hunter labelled eledoisin binding sites in rat spinal cord by quantitative autoradiography.
Topics: Animals; Autoradiography; Binding Sites; Cerebral Cortex; Eledoisin; Iodine Radioisotopes; Male; Neurokinin A; Neurokinin B; Neuropeptides; Rats; Spinal Cord; Substance P; Succinimides | 1987 |
Comparison of the responses to the sensory neuropeptides, substance P, neurokinin A, neurokinin B and calcitonin gene-related peptide and to trigeminal nerve stimulation in the iris sphincter muscle of the rabbit.
Topics: Animals; Atropine; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Eledoisin; Female; Iris; Kinins; Male; Muscle Contraction; Neurokinin A; Neurokinin B; Neuropeptides; Physalaemin; Potassium Chloride; Rabbits; Substance P; Trigeminal Nerve | 1987 |
Several mediators appear to interact in neurogenic inflammation.
Topics: Animals; Blood Proteins; Calcitonin Gene-Related Peptide; In Vitro Techniques; Inflammation; Neurokinin A; Neurokinin B; Neuropeptides; Rabbits; Rats; Rats, Inbred Strains; Substance P; Vasodilation | 1987 |
Selective agonists for substance P and neurokinin receptors.
Topics: Animals; Dogs; Neurokinin A; Neurokinin B; Neuropeptides; Peptide Fragments; Protein Conformation; Rabbits; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Structure-Activity Relationship; Substance P | 1987 |
Monoclonal antibodies to substance P: production, characterization of their fine specificities, and use in immunocytochemistry.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens; Female; Ganglia, Sympathetic; Hybridomas; Immunization; Immunoenzyme Techniques; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neurokinin A; Neurokinin B; Neuropeptides; Peptide Fragments; Radioimmunoassay; Rats; Spinal Cord; Substance P | 1987 |
Senktide, a selective neurokinin B-like agonist, elicits serotonin-mediated behaviour following intracisternal administration in the mouse.
Topics: Animals; Eledoisin; Female; Mice; Neurokinin B; Neuropeptides; Oligopeptides; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Serotonin; Serotonin Antagonists; Stereotyped Behavior; Substance P | 1987 |
Interaction of tachykinins with their receptors studied with cyclic analogues of substance P and neurokinin B.
Topics: Amino Acid Sequence; Animals; Brain Chemistry; Dogs; Guinea Pigs; Ileum; Male; Molecular Conformation; Neurokinin B; Neuropeptides; Rabbits; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Synaptosomes | 1987 |
Receptors for substance P on isolated intestinal smooth muscle cells of the guinea pig.
Topics: Animals; Binding, Competitive; Guinea Pigs; Intestinal Mucosa; Iodine Radioisotopes; Kinetics; Muscle, Smooth; Neurokinin A; Neurokinin B; Neuropeptides; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P | 1987 |
Peptide receptors in the airways.
Topics: Animals; Bradykinin; Carotid Arteries; Dogs; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Neuropeptides; Portal Vein; Rats; Receptors, Neurotransmitter; Substance P; Trachea | 1987 |
Subcellular distribution of mammalian tachykinins in rat basal ganglia.
Topics: Animals; Basal Ganglia; Caudate Nucleus; Cell Fractionation; Chromatography, High Pressure Liquid; Dopamine; Female; Microscopy, Electron; Neurokinin A; Neurokinin B; Neuropeptides; Norepinephrine; Putamen; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra; Synaptic Vesicles; Synaptosomes; Tachykinins | 1988 |
Enkephalinase inhibitor potentiates mammalian tachykinin-induced contraction in ferret trachea.
Topics: Animals; Atropine; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Epithelium; Ferrets; In Vitro Techniques; Metalloendopeptidases; Muscle Contraction; Neprilysin; Neurokinin A; Neurokinin B; Neuropeptides; Substance P; Tachykinins; Thiorphan; Tiopronin; Trachea | 1987 |
Effects of three mammalian tachykinins on single enteric neurons.
Topics: Animals; Electrophysiology; Guinea Pigs; Intestine, Small; Male; Myenteric Plexus; Neurokinin A; Neurokinin B; Neurons; Neuropeptides; Substance P | 1987 |
Huntington's disease: changes in tachykinin content in postmortem brains.
Topics: Animals; Brain; Humans; Huntington Disease; Immunohistochemistry; Male; Neurokinin A; Neurokinin B; Neuropeptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P; Tachykinins | 1987 |
Substance P, nicotinic acetylcholine receptors and antinociception in the rat.
Topics: Analgesics; Animals; Hexamethonium Compounds; Injections, Intraventricular; Male; Mecamylamine; Naloxone; Neurokinin A; Neurokinin B; Neuropeptides; Nicotine; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Cholinergic; Substance P | 1987 |
Contractile response of the human isolated urinary bladder to neurokinins: involvement of NK-2 receptors.
Topics: Aged; Female; Humans; In Vitro Techniques; Isometric Contraction; Male; Middle Aged; Neurokinin A; Neurokinin B; Neuropeptides; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Urinary Bladder | 1988 |
Characterization of the effects produced by neurokinins and three agonists selective for neurokinin receptor subtypes in a spinal nociceptive reflex of the rat.
Topics: Adrenalectomy; Animals; Bradykinin; Dioxanes; Hot Temperature; Idazoxan; Male; Naloxone; Neurokinin A; Neurokinin B; Neuropeptides; Nociceptors; Pain Measurement; Peptide Fragments; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Spinal Cord; Substance P | 1988 |
Tachykinin-induced phosphoinositide breakdown in airway smooth muscle and epithelium: relationship to contraction.
Topics: Animals; Epithelium; Guinea Pigs; In Vitro Techniques; Kinins; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Neuropeptides; Oligopeptides; Phosphatidylinositols; Substance P; Tachykinins; Trachea | 1988 |
Distribution of cells containing mRNAs encoding substance P and neurokinin B in the rat central nervous system.
Topics: Animals; Autoradiography; Brain; Brain Mapping; Male; Neurokinin B; Neuropeptides; Nucleic Acid Hybridization; Rats; Rats, Inbred Strains; RNA, Messenger; Spinal Cord; Substance P | 1988 |
Pharmacological studies of grooming and scratching behavior elicited by spinal substance P and excitatory amino acids.
Topics: Amino Acids; Animals; Behavior, Animal; Grooming; Injections, Spinal; Neurokinin A; Neurokinin B; Neuropeptides; Serotonin; Serotonin Antagonists; Somatostatin; Spinal Cord; Substance P; Tryptamines | 1988 |
Neurokinins induce a relaxation of the rat duodenum "in vivo" by activating postganglionic sympathetic elements in prevertebral ganglia: involvement of an NK-2 type of neurokinin receptor.
Topics: Adrenalectomy; Animals; Duodenum; Guanethidine; Kassinin; Male; Muscle Contraction; Muscle Relaxation; Neurokinin A; Neurokinin B; Neuropeptides; Norepinephrine; Oligopeptides; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1988 |
Capsaicin-sensitive tachykinin-like immunoreactivity in the thymus of rats and guinea-pigs.
Topics: Animals; Capsaicin; Chromatography, High Pressure Liquid; Cricetinae; Eledoisin; Guinea Pigs; Immunologic Techniques; Mice; Neurokinin A; Neurokinin B; Neuropeptides; Rats; Species Specificity; Substance P; Tachykinins; Thymus Gland | 1988 |
Receptor binding sites for substance P and substance K in the canine gastrointestinal tract and their possible role in inflammatory bowel disease.
Topics: Animals; Digestive System; Dogs; Gastrointestinal Diseases; Neurokinin A; Neurokinin B; Neurons; Neuropeptides; Substance P | 1988 |
[Quantification of neurokinin A neurokinin B, and substance P in the guinea pig lung by high performance liquid chromatography and subsequent radioimmunoassay].
Topics: Animals; Bronchi; Chromatography, High Pressure Liquid; Guinea Pigs; Lung; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Neuropeptides; Radioimmunoassay; Substance P | 1988 |
NK-1 receptors mediate the tachykinin stimulation of salivary secretion: selective agonists provide further evidence.
Topics: Animals; Male; Neurokinin A; Neurokinin B; Neuropeptides; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Salivation; Substance P; Tachykinins | 1988 |
Synthesis and immunological evaluation of N-terminal, noncrossreactive tachykinin antigens.
Topics: Animals; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Female; Mice; Mice, Inbred BALB C; Neurokinin A; Neurokinin B; Substance P; Tachykinins | 1988 |
Comparison of the effects of epithelium removal and of an enkephalinase inhibitor on the neurokinin-induced contractions of guinea-pig isolated trachea.
Topics: Airway Resistance; Animals; Epithelium; Guinea Pigs; In Vitro Techniques; Male; Neprilysin; Neurokinin A; Neurokinin B; Substance P; Tachykinins; Thiorphan; Trachea | 1988 |
Mammalian tachykinins modulate the nicotinic secretory response of cultured bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Catecholamines; Cattle; Cells, Cultured; Neurokinin A; Neurokinin B; Nicotine; Receptors, Nicotinic; Recombinant Proteins; Substance P | 1988 |
The mechanism of tachykinin-induced bronchoconstriction in the rat.
Topics: Airway Resistance; Animals; Bronchi; Dose-Response Relationship, Drug; Eledoisin; Kassinin; Lung Compliance; Male; Neurokinin A; Neurokinin B; Rats; Rats, Inbred F344; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins; Vagotomy | 1988 |
The tachykinin NH2-senktide, a selective neurokinin B receptor agonist, is a very potent inhibitor of salt appetite in the rat.
Topics: Animals; Appetite; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Neurokinin B; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Neurokinin-3; Receptors, Neurotransmitter; Sodium Chloride; Substance P; Tachykinins | 1988 |
Characterization of the effects of neurokinins on canine antral muscle.
Topics: Acetylcholine; Animals; Atropine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dogs; Female; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Pyloric Antrum; Reference Values; Substance P; Tetrodotoxin | 1988 |
Involvement of substance P in noncholinergic excitation of rabbit colonic muscle.
Topics: Acetylcholine; Animals; Atropine; Calcium; Colon; Electric Stimulation; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Male; Muscle Contraction; Neurokinin A; Neurokinin B; Rabbits; Substance P | 1989 |
Substance P, neurokinin A and neurokinin B in the ocular response to injury in the rabbit.
Topics: Animals; Electric Stimulation; Eye; Eye Injuries; Female; In Vitro Techniques; Infrared Rays; Male; Muscle, Smooth; Neurokinin A; Neurokinin B; Pupil; Rabbits; Radioimmunoassay; Substance P | 1988 |
Effects and interactions of sensory neuropeptides on airway microvascular leakage in guinea-pigs.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capillary Permeability; Guinea Pigs; Male; Neurokinin A; Neurokinin B; Neuropeptides; Receptors, Neurotransmitter; Receptors, Tachykinin; Respiratory System; Substance P | 1988 |
Neurokinin B and substance P genes are co-expressed in a subset of neurons in the rat habenula.
Topics: Animals; Histocytochemistry; Male; Neurokinin B; Rats; Rats, Inbred Strains; RNA, Messenger; Substance P; Thalamus | 1989 |
Prostacyclin release induced by neurokinins in cultured human endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Humans; Neurokinin A; Neurokinin B; Substance P | 1989 |
Interactions between the tachykinins and calcitonin gene-related peptide lead to the modulation of oedema formation and blood flow in rat skin.
Topics: Animals; Calcitonin Gene-Related Peptide; Drug Interactions; Edema; Histamine Antagonists; Male; Neurokinin A; Neurokinin B; Neuropeptides; Rats; Rats, Inbred Strains; Regional Blood Flow; Rheology; Serotonin Antagonists; Skin; Substance P; Tachykinins | 1989 |
Neutral endopeptidase modulates tachykinin-induced increase in vascular permeability in guinea pig skin.
Topics: Animals; Capillary Permeability; Endopeptidases; Guinea Pigs; Male; Neurokinin B; Protease Inhibitors; Skin; Substance P; Tachykinins | 1989 |
Cardiovascular roles of tachykinin peptides in the nucleus tractus solitarii of rats.
Topics: Animals; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; Heart Rate; Male; Medulla Oblongata; Microinjections; Neurokinin A; Neurokinin B; Peptide Fragments; Rats; Rats, Inbred Strains; Substance P | 1989 |
Substance p in the median eminence and pituitary of the rat: demonstration of immunoreactive fibers and specific binding sites.
Topics: Animals; Immunohistochemistry; Iodine Radioisotopes; Male; Median Eminence; Neurokinin A; Neurokinin B; Neurons; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P | 1989 |
Tachykinins produce fast and slow depolarizations in sympathetic neurons of rat coeliac-superior mesenteric ganglia.
Topics: Animals; Ganglia, Sympathetic; In Vitro Techniques; Membrane Potentials; Mesentery; Neurokinin A; Neurokinin B; Rats; Substance P | 1989 |
Effects of tachykinins and selective tachykinin receptor agonists on vascular permeability in the rat lower urinary tract: evidence for the involvement of NK-1 receptors.
Topics: Animals; Blood Pressure; Capillary Permeability; Cimetidine; Diphenhydramine; Kassinin; Male; Methysergide; Neurokinin A; Neurokinin B; Physalaemin; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins; Urinary Tract | 1989 |
Characterization of neurokinin effects and receptor selectivity in human isolated bronchi.
Topics: Acetylcholine; Bronchi; Epithelium; Glycopeptides; Humans; In Vitro Techniques; Muscle Contraction; Neurokinin A; Neurokinin B; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Neurotransmitter; Substance P | 1989 |
Regulation of epithelial transport in the jejunal mucosa of the guinea pig by neurokinins.
Topics: Animals; Atropine; Biological Transport; Calcitonin Gene-Related Peptide; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Jejunum; Male; Neurokinin A; Neurokinin B; Substance P; Tachykinins; Tetrodotoxin | 1989 |
Contractile activity of the N-acylated C-terminal part of substance P7-11 in guinea pig trachea. Effect of epithelium removal.
Topics: Animals; Epithelium; Guinea Pigs; In Vitro Techniques; Indicators and Reagents; Male; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptide Fragments; Substance P; Trachea | 1989 |
Central pressor actions of neurokinin B: increases in neurokinin B contents in discrete nuclei in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Neurokinin B; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Substance P | 1989 |
The hamster isolated trachea: a new preparation for studying NK-2 receptors.
Topics: Animals; Atropine; Cricetinae; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Pyrilamine; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Tachykinins; Thiorphan; Trachea | 1989 |
Capillary permeability induced by intravenous neurokinins. Receptor characterization and mechanism of action.
Topics: Animals; Blood Proteins; Capillary Permeability; Evans Blue; Female; Injections, Intravenous; Kinins; Male; Mast Cells; Neurokinin A; Neurokinin B; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Skin; Substance P | 1989 |
In vitro human polymorphonuclear leukocyte chemokinesis and human monocyte chemotaxis are different activities of aminoterminal and carboxyterminal substance P.
Topics: Calcitonin Gene-Related Peptide; Chemotaxis; Chemotaxis, Leukocyte; Humans; In Vitro Techniques; Monocytes; Neurokinin A; Neurokinin B; Neutrophils; Substance P | 1989 |
Distribution, projection and dopaminergic regulation of the neurokinin B mRNA-containing neurons of the rat caudate-putamen.
Topics: Animals; Caudate Nucleus; Cell Count; Dopamine; Enkephalins; Hydroxydopamines; Male; Neurokinin B; Nucleic Acid Hybridization; Oxidopamine; Putamen; Rats; Rats, Inbred Strains; RNA, Messenger; Substance P; Substantia Nigra | 1989 |
Stimulation of human B lymphocyte differentiation by the neuropeptides substance P and neurokinin A.
Topics: Amino Acid Sequence; B-Lymphocytes; Cells, Cultured; Herpesvirus 4, Human; Humans; Immunoglobulins; Lymphocyte Activation; Molecular Sequence Data; Neurokinin B; Staphylococcal Protein A; Substance P; Viral Plaque Assay | 1989 |
Effect of sensory neuropeptides on canine bronchial and pulmonary vessels in vitro.
Topics: Animals; Bronchial Arteries; Calcitonin Gene-Related Peptide; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Neuropeptides; Pulmonary Artery; Pulmonary Circulation; Pulmonary Veins; Substance P; Vasodilation | 1989 |
Effects of neurokinins on ion transport and sulfated macromolecule release in the isolated ferret trachea.
Topics: Amiloride; Animals; Biological Transport; Bumetanide; Chlorides; Electrodes; Ferrets; In Vitro Techniques; Macromolecular Substances; Male; Neurokinin A; Neurokinin B; Peptide Fragments; Sodium; Substance P; Sulfates; Trachea | 1989 |
Characterization of the peripheral action of neurokinins and neurokinin receptor selective agonists on the rat cardiovascular system.
Topics: Animals; Cardiovascular System; Female; Injections, Intravenous; Male; Neurokinin A; Neurokinin B; Neurons, Afferent; Parasympathetic Nervous System; Peptide Fragments; Prostaglandins; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Substance P; Sympathetic Nervous System; Tachycardia | 1989 |
Effects of tachykinins on mucus secretion in human bronchi in vitro.
Topics: Adolescent; Adult; Aged; Bronchi; Child; Female; Glycopeptides; Humans; In Vitro Techniques; Male; Middle Aged; Mucus; Neprilysin; Neurokinin A; Neurokinin B; Substance P; Tachykinins | 1989 |
[Developmental changes in tachykinin response of the isolated rat duodenum].
Topics: Age Factors; Animals; Duodenum; Gastrointestinal Motility; In Vitro Techniques; Neurokinin A; Neurokinin B; Rats; Rats, Inbred Strains; Substance P | 1989 |
Expression and cellular localization of substance P/neurokinin A and neurokinin B mRNAs in the rat retina.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Autoradiography; Fluorescent Antibody Technique; Gene Expression; Male; Molecular Sequence Data; Neurokinin A; Neurokinin B; Nucleic Acid Hybridization; Plasmids; Rats; Rats, Inbred Strains; Retina; RNA Probes; RNA, Antisense; RNA, Messenger; Substance P | 1989 |
Specific neuroanatomical and neurochemical correlates of grooming and satiety effects of bombesin.
Topics: Animals; Bombesin; Feeding Behavior; Gastrin-Releasing Peptide; Grooming; Male; Medulla Oblongata; Neurokinin B; Neuropeptide Y; Nucleus Accumbens; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Satiation; Substance P | 1988 |
Demonstration of two distinct tachykinin receptors in rat brain cortex.
Topics: Animals; Cell Membrane; Cerebral Cortex; Chlorides; Eledoisin; Guanylyl Imidodiphosphate; Indicators and Reagents; Kassinin; Manganese; Manganese Compounds; Neurokinin B; Oligopeptides; Peptide Fragments; Physalaemin; Rats; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Succinimides | 1985 |
Mammalian tachykinin-induced hydrolysis of inositol phospholipids in rat brain slices.
Topics: Animals; Brain; Cyclic AMP; Hydrolysis; In Vitro Techniques; Male; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Phosphatidylinositols; Rats; Rats, Inbred Strains; Substance P | 1985 |
Regional distribution and in vivo release of tachykinin-like immunoreactivities in rat brain: evidence for regional differences in relative proportions of tachykinins.
Topics: Animals; Brain Chemistry; Corpus Striatum; Dialysis; Eledoisin; Kassinin; Male; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Physalaemin; Potassium; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P; Tachykinins; Tissue Extracts | 1985 |
Comparison of cardiovascular and bronchoconstrictor effects of substance P, substance K and other tachykinins.
Topics: Animals; Bombesin; Bronchi; Eledoisin; Guinea Pigs; Hemodynamics; In Vitro Techniques; Kassinin; Male; Muscle, Smooth; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Physalaemin; Respiration; Substance P; Time Factors | 1984 |
The excitatory action of the newly-discovered mammalian tachykinins, neurokinin alpha and neurokinin beta, on neurons of the isolated spinal cord of the newborn rat.
Topics: Animals; Animals, Newborn; In Vitro Techniques; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Synaptic Transmission | 1984 |
Regional distribution of substance P, neurokinin alpha and neurokinin beta in rat central nervous system.
Topics: Animals; Central Nervous System; Cerebellum; Cerebral Cortex; Corpus Striatum; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Substantia Nigra | 1984 |
Pharmacological characterization of novel mammalian tachykinins, neurokinin alpha and neurokinin beta.
Topics: Animals; Chemical Phenomena; Chemistry; Duodenum; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Rats; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Vas Deferens | 1984 |
Comparative potencies of substance P, substance K and neuromedin K on brain substance P receptors.
Topics: Animals; Binding Sites; Binding, Competitive; Male; Neurokinin A; Neurokinin B; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Neurokinin-1; Substance P | 1984 |
Tachykinin-like central activity of neuromedin K in mice.
Topics: Animals; Behavior, Animal; Brain; Eledoisin; Kassinin; Male; Mice; Neurokinin B; Oligopeptides; Peptides; Physalaemin; Substance P; Tachykinins | 1984 |
Regional distribution of neuromedin K and neuromedin L in rat brain and spinal cord.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Cross Reactions; Immune Sera; Male; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Oligopeptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Tissue Distribution | 1984 |
Parallel bioassay of PG-SPI, an amphibian acidic SP-like peptide, mammalian basic substance P, and neurokinins A and B on in vitro and in vivo test systems.
Topics: Amino Acid Sequence; Animals; Biological Assay; Biphenyl Compounds; Cricetinae; Evaluation Studies as Topic; Gastric Mucosa; Guinea Pigs; Injections, Intraventricular; Male; Molecular Sequence Data; Neurokinin A; Neurokinin B; Oligopeptides; Organ Culture Techniques; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rabbits; Ranidae; Rats; Rats, Wistar; Receptors, Tachykinin; Substance P | 1995 |
Electrophysiological effects of tachykinins and capsaicin on guinea-pig bronchial parasympathetic ganglion neurones.
Topics: Animals; Bronchi; Capsaicin; Electrophysiology; Ganglia, Parasympathetic; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Microelectrodes; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neurons; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P; Tachykinins | 1993 |
Ontogeny of the distribution of tachykinins in rat cerebral cortex: immunocytochemistry and in situ hybridization histochemistry.
Topics: Aging; Animals; Cerebral Cortex; Histocytochemistry; Immunohistochemistry; In Situ Hybridization; Neurokinin B; Protein Precursors; Rats; Rats, Sprague-Dawley; Substance P; Tachykinins; Tissue Distribution | 1994 |
Involvement of neurokinins in the non-cholinergic response to activation of 5-HT3 and 5-HT4 receptors in guinea-pig ileum.
Topics: 5-Methoxytryptamine; Acetylcholine; Animals; Atropine; Autonomic Nervous System; Choline; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin B; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Substance P | 1994 |
A study of tachykinin-immunoreactivity in the cat visual cortex.
Topics: Animals; Antibodies, Monoclonal; Cats; Immunohistochemistry; Neurokinin A; Neurokinin B; Neurons; Presynaptic Terminals; Substance P; Tachykinins; Visual Cortex | 1994 |
Multiple types of tachykinin receptor mediate a slow excitation of rat spinal motoneurones in vitro.
Topics: Animals; Animals, Newborn; Female; In Vitro Techniques; Male; Membrane Potentials; Motor Neurons; Neurokinin A; Neurokinin B; Peptide Fragments; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Spinal Cord; Substance P; Tetrodotoxin | 1994 |
Cardiovascular and behavioural effects of centrally administered tachykinins in the rat: characterization of receptors with selective antagonists.
Topics: Animals; Behavior, Animal; Benzamides; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Indoles; Injections, Intraventricular; Isoindoles; Male; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Oligopeptides; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P; Tachykinins | 1994 |
Differences in the regional and cellular localization of c-fos messenger RNA induced by amphetamine, cocaine and caffeine in the rat.
Topics: Amphetamine; Animals; Biomarkers; Brain; Caffeine; Choline O-Acetyltransferase; Cocaine; Corpus Striatum; Dopamine; Enkephalins; Gene Expression Regulation; Genes, fos; Male; Nerve Tissue Proteins; Neurokinin B; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Somatostatin; Substance P | 1994 |
Establishment of a cellular assay system for G protein-linked receptors: coupling of human NK2 and 5-HT2 receptors to phospholipase C activates a luciferase reporter gene.
Topics: Biological Assay; Cell Line; Gene Expression Regulation; Genes, Reporter; GTP-Binding Proteins; Humans; Intercellular Adhesion Molecule-1; Luciferases; Neurokinin A; Neurokinin B; Phosphatidylinositols; Receptors, Neurokinin-2; Receptors, Serotonin; Second Messenger Systems; Substance P; Transfection; Type C Phospholipases | 1993 |
Epithelium modulates the kinetics of the response to substance P and its intrinsic activity in the guinea-pig trachea.
Topics: Animals; Carbachol; Epithelium; Guinea Pigs; Histamine; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Neprilysin; Neurokinin A; Neurokinin B; Substance P; Thiorphan; Trachea | 1994 |
Structural comparison of NK2 receptor agonists and antagonists.
Topics: Amino Acid Sequence; Drug Design; Models, Molecular; Molecular Sequence Data; Molecular Structure; Neurokinin A; Neurokinin B; Peptide Fragments; Protein Conformation; Receptors, Neurokinin-2; Substance P; Tachykinins; Thermodynamics | 1994 |
Tachykinin-induced contractions in the circular muscle of guinea pig ileum.
Topics: Animals; Atropine; Biphenyl Compounds; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptides, Cyclic; Rats; Structure-Activity Relationship; Substance P; Tachykinins; Tetrodotoxin | 1994 |
On the nature of the 5-HT receptor subtype inhibiting acetylcholine release in the guinea-pig ileum.
Topics: Acetylcholine; Animals; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neurokinin B; Peptide Fragments; Receptors, Neurokinin-3; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substance P | 1994 |
Tachykinins induce a [Ca2+]i rise in the acinar cells of feline tracheal submucosal gland.
Topics: Animals; Calcium; Cats; Exocrine Glands; Fura-2; Glycoproteins; In Vitro Techniques; Indicators and Reagents; Mucins; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Receptors, Neurokinin-2; Substance P; Tachykinins; Trachea | 1994 |
Neurokinin B gene expression is increased in the arcuate nucleus of ovariectomized rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Autoradiography; Estradiol; Estrogens, Conjugated (USP); Female; Gene Expression; Image Processing, Computer-Assisted; In Situ Hybridization; Neurokinin B; Ovariectomy; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P | 1994 |
Characterisation of [125I][MePhe7]neurokinin B binding to tachykinin NK3 receptors: evidence for interspecies variance.
Topics: Amino Acid Sequence; Animals; Benzamides; Binding, Competitive; Cerebral Cortex; CHO Cells; Cricetinae; Cricetulus; Guinea Pigs; Humans; Molecular Sequence Data; Neurokinin B; Peptide Fragments; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Receptors, Tachykinin; Regression Analysis; Substance P | 1994 |
Substance P in intervertebral discs. Binding sites on vascular endothelium of the human annulus fibrosus.
Topics: Adult; Binding Sites; Endothelium, Vascular; Female; Guanylyl Imidodiphosphate; Humans; Intervertebral Disc; Iodine Radioisotopes; Male; Middle Aged; Neurokinin A; Neurokinin B; Receptors, Neurokinin-1; Substance P | 1994 |
Tachykinin NK3 receptor mediates NANC hyperpolarization and relaxation via nitric oxide release in the circular muscle of the guinea-pig colon.
Topics: Animals; Apamin; Arginine; Atropine; Colon; Dose-Response Relationship, Drug; Guanethidine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Neurokinin B; Nitric Oxide; Nitroarginine; Oligopeptides; Peptide Fragments; Piperidines; Quinuclidines; Receptors, Neurokinin-3; Stereoisomerism; Substance P; Tetrodotoxin | 1994 |
In vitro effects of tachykinins on the smooth musculature of horse gut.
Topics: Analysis of Variance; Animals; Atropine; Colon; Dose-Response Relationship, Drug; Duodenum; Electrophysiology; Eledoisin; Horses; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Regression Analysis; Substance P; Tetrodotoxin | 1994 |
Effects of tachykinins on the splanchnic circulation: a comparison of the dog and rat.
Topics: Animals; Dogs; Female; Hemodynamics; Male; Mesenteric Artery, Superior; Neurokinin A; Neurokinin B; Rats; Rats, Wistar; Species Specificity; Splanchnic Circulation; Substance P; Tachykinins; Vascular Resistance; Vasodilation | 1994 |
Tachykinin receptors involved in the contractile effect of the natural tachykinins in the rat gastric fundus.
Topics: Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Gastric Fundus; Indoles; Isoindoles; Male; Methacholine Chloride; Muscle Contraction; Neurokinin A; Neurokinin B; Peptide Fragments; Peptides, Cyclic; Rats; Receptors, Tachykinin; Substance P; Tachykinins | 1994 |
GR138676, a novel peptidic tachykinin antagonist which is potent at NK3 receptors.
Topics: Amino Acid Sequence; Animals; Arachidonic Acid; Astrocytoma; Binding, Competitive; Calcium; CHO Cells; Cricetinae; Humans; Male; Molecular Sequence Data; Neurokinin B; Oligopeptides; Peptide Fragments; Portal Vein; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Transfection; Tumor Cells, Cultured | 1994 |
Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo.
Topics: Analysis of Variance; Animals; Cell Membrane; Corpus Striatum; Endocytosis; Endosomes; GTP-Binding Proteins; Immunohistochemistry; Kinetics; Male; Microscopy, Immunoelectron; Neurokinin A; Neurokinin B; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Tissue Distribution | 1995 |
The formalin-induced expression of tachykinin peptide and neurokinin receptor messenger RNAs in rat sensory ganglia and spinal cord is modulated by opiate preadministration.
Topics: Animals; Formaldehyde; Ganglia, Spinal; Gene Expression Regulation; Male; Morphine; Naltrexone; Neurokinin B; Pain; Premedication; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-3; RNA, Messenger; Spinal Cord; Substance P; Time Factors | 1995 |
The action of substance P methyl ester on cochlear potentials in the guinea pig.
Topics: Action Potentials; Animals; Cochlea; Cochlear Microphonic Potentials; Dose-Response Relationship, Drug; Guinea Pigs; Neurokinin A; Neurokinin B; Peptide Fragments; Reaction Time; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P | 1995 |
Pharmacology of tachykinin receptors on neurones in the ventral tegmental area of rat brain slices.
Topics: Action Potentials; Animals; Electrophysiology; In Vitro Techniques; Microelectrodes; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neurons; Peptide Fragments; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P; Ventral Tegmental Area | 1995 |
Nonselective cation channels coupled with tachykinin receptors in rat sensory neurons.
Topics: Animals; Cations; Cells, Cultured; Electric Conductivity; Electrophysiology; Female; Ganglia, Spinal; Ion Channels; Ions; Male; Neurokinin B; Neurons, Afferent; Permeability; Rats; Rats, Wistar; Receptors, Tachykinin; Substance P | 1995 |
Tachykinin effects on bladder activity in conscious normal rats.
Topics: Administration, Intravesical; Animals; Benzamides; Female; Indoles; Injections, Intra-Arterial; Isoindoles; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Substance P; Urinary Bladder; Urination | 1995 |
Pharmacological evidence for neurokinin receptors in murine neuroblastoma C1300 cells.
Topics: Animals; Benzamides; Calcium; Cell Line; Kinetics; Mice; Neuroblastoma; Neurokinin A; Neurokinin B; Piperidines; Receptors, Tachykinin; Substance P; Tumor Cells, Cultured | 1995 |
Presence and actions of vasoactive intestinal peptide in the isolated rabbit heart.
Topics: Animals; Coronary Circulation; Ganglia; Heart; Immunohistochemistry; In Vitro Techniques; Male; Myocardium; Neurokinin A; Neurokinin B; Neurons; Rabbits; Substance P; Vasoactive Intestinal Peptide; Vasodilation | 1995 |
Effects of the tachykinin NK1 receptor antagonist, RP 67580, on central cardiovascular and behavioural effects of substance P, neurokinin A and neurokinin B.
Topics: Animals; Behavior, Animal; Cardiovascular System; Indoles; Injections, Intraventricular; Isoindoles; Male; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Rats; Rats, Wistar; Substance P; Tachykinins | 1995 |
Identification of residues involved in ligand binding to the neurokinin-2 receptor.
Topics: Amino Acid Sequence; Benzamides; Binding Sites; DNA Mutational Analysis; Dose-Response Relationship, Drug; Humans; Ligands; Molecular Sequence Data; Neurokinin A; Neurokinin B; Peptide Fragments; Phosphatidylinositols; Piperidines; Receptors, Neurokinin-2; Recombinant Proteins; Signal Transduction; Structure-Activity Relationship; Substance P; Tachykinins | 1995 |
Tachykinin receptors mediating contraction of guinea pig lung strips.
Topics: Acetylcholine; Animals; Benzamides; Biphenyl Compounds; Dipeptides; Guinea Pigs; In Vitro Techniques; Lung; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P; Trachea | 1995 |
Peptide structural requirements for antagonism differ between the two mammalian bombesin receptor subtypes.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Bombesin; Esophagus; Gastrin-Releasing Peptide; Glioma; Male; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neurokinin B; Pancreas; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Bombesin; Structure-Activity Relationship; Substance P | 1995 |
Endothelium-dependent contraction in intrapulmonary arteries: mediation by endothelial NK1 receptors and TXA2.
Topics: Animals; Cyclooxygenase Inhibitors; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Rabbits; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Tachykinins; Thromboxane A2; Thromboxane-A Synthase | 1995 |
Non-peptide antagonists, CP-96,345 and RP 67580, distinguish species variants in tachykinin NK1 receptors.
Topics: Animals; Binding Sites; Biphenyl Compounds; Carbachol; Cell Line; Female; Guinea Pigs; Humans; Hydrolysis; Ileum; Indoles; Inositol Phosphates; Isoindoles; Male; Muscle, Smooth; Neurokinin B; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tumor Cells, Cultured | 1993 |
Tachykinin control of ferret airways: mucus secretion, bronchoconstriction and receptor mapping.
Topics: Animals; Bronchoconstriction; Capsaicin; Ferrets; Male; Methacholine Chloride; Mucus; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Reproducibility of Results; Stimulation, Chemical; Substance P; Tachykinins; Trachea | 1993 |
The rabbit iris sphincter contains NK1 and NK3 but not NK2 receptors: a study with selective agonists and antagonists.
Topics: Animals; Dactinomycin; Female; Iris; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptide Fragments; Rabbits; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P | 1993 |
Characterization of the binding of [125I-iodo-histidyl, methyl-Phe7] neurokinin B to the neurokinin-3 receptor.
Topics: Animals; Cell Membrane; Cells, Cultured; Cerebral Cortex; CHO Cells; Cricetinae; Humans; Neurokinin A; Neurokinin B; Rats; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Recombinant Proteins; Substance P | 1993 |
NK1 receptors mediate tachykinin-induced increase in microvascular clearance in hamster cheek pouch.
Topics: Animals; Biphenyl Compounds; Capsaicin; Cheek; Cricetinae; Macromolecular Substances; Male; Mesocricetus; Microcirculation; Neurokinin A; Neurokinin B; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Tachykinins | 1993 |
Site-specific effects of intracerebral injections of three neurokinins (neurokinin A, neurokinin K, and neurokinin gamma) on the expression of male rat sexual behavior.
Topics: Amygdala; Animals; Brain Mapping; Copulation; Dose-Response Relationship, Drug; Ejaculation; Male; Neural Pathways; Neurokinin A; Neurokinin B; Peptide Fragments; Preoptic Area; Rats; Reaction Time; Sexual Behavior, Animal; Substance P; Tachykinins | 1993 |
Sodium cromoglycate: evidence of tachykinin antagonist activity in the human skin.
Topics: Adult; Autoradiography; Capillary Permeability; Chromatography, Gel; Chromatography, High Pressure Liquid; Cromolyn Sodium; Dinoprostone; Histamine Antagonists; Humans; Injections, Intradermal; Iodine Radioisotopes; Male; Neurokinin B; Skin; Skin Tests; Solvents; Substance P; Succinimides; Tachykinins | 1993 |
1H nuclear magnetic resonance determination of the membrane-bound conformation of senktide, a highly selective neurokinin B agonist.
Topics: Amino Acid Sequence; Liposomes; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Neurokinin B; Peptide Fragments; Protein Conformation; Solutions; Substance P; Thermodynamics; Water | 1993 |
Immunohistochemical distribution, biochemical characterization, and biological action of tachykinins in the frog adrenal gland.
Topics: 6-Ketoprostaglandin F1 alpha; Adrenal Cortex Hormones; Adrenal Glands; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Dinoprostone; Fluorescent Antibody Technique; Immunohistochemistry; Male; Microscopy, Immunoelectron; Molecular Sequence Data; Neurokinin A; Neurokinin B; Rana ridibunda; Substance P; Tachykinins; Tissue Distribution | 1993 |
Scratching behavior induced by bombesin-related peptides. Comparison of bombesin, gastrin-releasing peptide and phyllolitorins.
Topics: Amino Acid Sequence; Animals; Bombesin; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Gastrin-Releasing Peptide; Grooming; Injections, Intraventricular; Male; Molecular Sequence Data; Neurokinin B; Oligopeptides; Peptide Fragments; Peptides; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Structure-Activity Relationship; Substance P | 1993 |
Tachykinins contract the circular muscle of the human esophageal body in vitro via NK2 receptors.
Topics: Adolescent; Adult; Aged; Atropine; Benzamides; Biphenyl Compounds; Carbachol; Dose-Response Relationship, Drug; Esophagus; Glycopeptides; Humans; Isometric Contraction; Middle Aged; Muscle Contraction; Muscle, Smooth; Neprilysin; Neurokinin A; Neurokinin B; Piperidines; Receptors, Tachykinin; Substance P; Tachykinins; Tetrodotoxin | 1993 |
A role for the C-terminal fragment of substance P,SP7-11 in the pathogenesis of arthritis.
Topics: Amino Acid Sequence; Animals; Arthritis; Cartilage, Articular; Cattle; Collagenases; Dinoprostone; Kinetics; Molecular Sequence Data; Neurokinin A; Neurokinin B; Peptide Fragments; Substance P | 1993 |
Neurokinin A, but not neurokinin B and substance P, induces codeine-resistant coughs in awake guinea-pigs.
Topics: Animals; Capsaicin; Codeine; Cough; Dose-Response Relationship, Drug; Drug Resistance; Guinea Pigs; Male; Neurokinin A; Neurokinin B; Substance P | 1993 |
Multiple actions of substance P and other tachykinins on sympathetic neurons in rat prevertebral ganglia.
Topics: Action Potentials; Animals; Electrophysiology; Evoked Potentials; Ganglia, Sympathetic; In Vitro Techniques; Membrane Potentials; Neurokinin A; Neurokinin B; Neurons; Rats; Receptors, Tachykinin; Substance P; Time Factors | 1993 |
Functional characterization of neurokinin receptors with agonists and antagonists.
Topics: Amino Acid Sequence; Animals; Biphenyl Compounds; Guinea Pigs; Molecular Sequence Data; Muscle, Smooth; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Portal Vein; Rabbits; Rats; Receptors, Tachykinin; Structure-Activity Relationship; Substance P; Tachykinins; Trachea; Venae Cavae | 1993 |
Blockade of cutaneous nerve-evoked responses by GR71251 in the isolated spinal cord preparation of newborn rat.
Topics: Animals; Animals, Newborn; Bombesin; Electric Stimulation; Evoked Potentials; Gastrin-Releasing Peptide; In Vitro Techniques; Neurokinin A; Neurokinin B; Peptides; Peripheral Nerves; Rats; Rats, Wistar; Skin; Spinal Cord; Substance P | 1993 |
Antiinflammatory and analgesic activity of CP-96,345: an orally active non-peptide substance P receptor antagonist.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Dose-Response Relationship, Drug; Evans Blue; Guinea Pigs; Histamine; Leukotriene D4; Male; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Platelet Activating Factor; Receptors, Neurokinin-1; Skin; Substance P; Ureter | 1993 |
Intranigral injection of selective neurokinin-1 and neurokinin-3 but not neurokinin-2 receptor agonists biphasically modulate striatal dopamine metabolism but not striatal preprotachykinin-A mRNA in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Female; Gene Expression Regulation; Injections; Neurokinin A; Neurokinin B; Peptide Fragments; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; RNA, Messenger; Substance P; Substantia Nigra; Tachykinins | 1993 |
Demonstration of a 'septide-sensitive' inflammatory response in rat skin.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Capillary Permeability; Dermatitis, Contact; Dose-Response Relationship, Drug; Edema; Indoles; Isoindoles; Male; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Nitric Oxide Synthase; p-Methoxy-N-methylphenethylamine; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 1995 |
Role of nitric oxide in tachykinin-induced increase in potential difference of rabbit tracheal mucosa.
Topics: Amiloride; Animals; Arginine; Electrophysiology; Epithelium; Histocytochemistry; Male; Membrane Potentials; Mucous Membrane; NADPH Dehydrogenase; Neurokinin A; Neurokinin B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Substance P; Tachykinins; Trachea | 1995 |
Further evidence that tachykinin-induced contraction of human isolated bronchus is mediated only by NK2-receptors.
Topics: Aged; Bronchi; Carbachol; Female; Glycopeptides; Humans; Male; Middle Aged; Muscle Contraction; Neurokinin A; Neurokinin B; Peptide Fragments; Protease Inhibitors; Receptors, Neurokinin-2; Substance P; Tachykinins | 1995 |
The design of dipeptide helical mimetics: the synthesis, tachykinin receptor affinity and conformational analysis of 1,1,6-trisubstituted indanes.
Topics: Amino Acid Sequence; Animals; Biological Assay; Crystallography, X-Ray; Dipeptides; Humans; Indans; Models, Molecular; Molecular Mimicry; Molecular Sequence Data; Molecular Structure; Neurokinin A; Neurokinin B; Protein Conformation; Receptors, Tachykinin; Structure-Activity Relationship; Substance P | 1996 |
The unpredicted high affinities of a large number of naturally occurring tachykinins for chimeric NK1/NK3 receptors suggest a role for an inhibitory domain in determining receptor specificity.
Topics: Amino Acid Sequence; Binding, Competitive; Humans; Ligands; Membrane Proteins; Molecular Sequence Data; Neurokinin A; Neurokinin B; Phosphatidylinositols; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Recombinant Fusion Proteins; Structure-Activity Relationship; Substance P; Tachykinins | 1996 |
Augmentation of neurally evoked cholinergic bronchoconstrictor responses by prejunctional NK2 receptors in the guinea-pig.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Biphenyl Compounds; Bronchoconstriction; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Male; Medulla Oblongata; Methacholine Chloride; Muscle, Smooth; Neurokinin A; Neurokinin B; Piperidines; Substance P | 1996 |
Tachykinins stimulate nitric oxide generation by canine cultured tracheal epithelium.
Topics: Animals; Arginine; Cells, Cultured; Dogs; Epithelium; Glycopeptides; Neurokinin A; Neurokinin B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Penicillamine; Receptors, Neurokinin-2; S-Nitroso-N-Acetylpenicillamine; Substance P; Trachea | 1995 |
Study of SR 142801, a new potent non-peptide NK3 receptor antagonist on cardiovascular responses in conscious guinea-pig.
Topics: Analysis of Variance; Animals; Blood Pressure; Dose-Response Relationship, Drug; Guinea Pigs; Heart Rate; Injections, Intravenous; Male; Neurokinin A; Neurokinin B; Peptide Fragments; Piperidines; Substance P | 1996 |
Effects of tachykinins on identified dorsal vagal neurons: an electrophysiological study in vitro.
Topics: Action Potentials; Animals; Brain Stem; Electrophysiology; Female; Histocytochemistry; In Vitro Techniques; Lysine; Male; Microelectrodes; Motor Neurons; Neurokinin A; Neurokinin B; Neurons; Rats; Rats, Wistar; Receptors, Tachykinin; Substance P; Tachykinins; Vagus Nerve | 1996 |
Involvement of tachykinin receptors in oedema formation and plasma extravasation induced by substance P, neurokinin A, and neurokinin B in mouse ear.
Topics: Animals; Capillary Permeability; Edema; Glycopeptides; Male; Mice; Neurokinin A; Neurokinin B; Piperidines; Quinuclidines; Receptors, Tachykinin; Substance P | 1996 |
In vivo exposure to nitrogen dioxide (NO2) induces a decrease in calcitonin gene-related peptide (CGRP) and tachykinin immunoreactivity in guinea-pig peripheral airways.
Topics: Administration, Inhalation; Air Pollutants; Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Environmental Exposure; Guinea Pigs; Immunoenzyme Techniques; Irritants; Lung; Male; Nerve Fibers; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Neurons, Afferent; Nitrogen Dioxide; Oxidants, Photochemical; Substance P; Tachykinins; Thiolester Hydrolases; Ubiquitin Thiolesterase | 1996 |
Evidence that tachykinins relax the guinea-pig trachea via nitric oxide release and by stimulation of a septide-insensitive NK1 receptor.
Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Neurokinin A; Neurokinin B; Nitric Oxide; Peptide Fragments; Pyrrolidonecarboxylic Acid; Receptors, Neurokinin-1; Substance P; Tachykinins; Trachea | 1996 |
Effect of a new dual neurokinin antagonist on airway smooth muscle in situ.
Topics: Animals; Dogs; Female; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Receptors, Neurokinin-2; Respiratory System; Substance P; Trachea | 1995 |
Functional expression of a novel human neurokinin-3 receptor homolog that binds [3H]senktide and [125I-MePhe7]neurokinin B, and is responsive to tachykinin peptide agonists.
Topics: Animals; Arachidonic Acid; Binding, Competitive; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Neurokinin B; Peptide Fragments; Radioligand Assay; Receptors, Neurokinin-3; Recombinant Proteins; Second Messenger Systems; Sequence Homology; Substance P; Tachykinins | 1997 |
Neurokinin induced inositol phosphate production in guinea pig bladder.
Topics: Adenylyl Cyclases; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Inositol Phosphates; Male; Neurokinin A; Neurokinin B; Substance P; Urinary Bladder | 1997 |
Characterization of NK3 receptors in rabbit isolated iris sphincter muscle.
Topics: Adrenergic alpha-Antagonists; Animals; Autoradiography; Benzamides; Electric Stimulation; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscle, Smooth; Neurokinin B; Peptide Fragments; Phenoxybenzamine; Piperidines; Rabbits; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P | 1997 |
Morphologic maturation of tachykinin peptide-expressing cells in the postnatal rabbit retina.
Topics: Age Factors; Animals; Animals, Newborn; Antibodies, Monoclonal; Immunohistochemistry; Neurokinin A; Neurokinin B; Rabbits; Retina; Retinal Ganglion Cells; Substance P; Tachykinins | 1997 |
Renal effects of intracerebroventricularly injected tachykinins in the conscious saline-loaded rat: receptor characterization.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Diuresis; Injections, Intraventricular; Kidney; Male; Natriuresis; Neurokinin A; Neurokinin B; Rats; Rats, Wistar; Receptors, Tachykinin; Substance P; Vasopressins | 1997 |
Substance P(6-11) and natural tachykinins interact with septide-sensitive tachykinin receptors coupled to a phospholipase C in the rat urinary bladder.
Topics: Analgesics; Animals; Benzamides; Binding Sites; Inositol Phosphates; Male; Neurokinin A; Neurokinin B; Neuropeptides; Peptide Fragments; Piperidines; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P; Tachykinins; Tritium; Type C Phospholipases; Urinary Bladder | 1997 |
Effect of angiotensin II on a spinal nociceptive reflex in the rat: receptor and mechanism of action.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Imidazoles; Injections, Spinal; Losartan; Male; Naloxone; Neurokinin A; Neurokinin B; Nociceptors; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord; Substance P; Tetrazoles | 1997 |
Mechanisms of electrolyte transport across the endometrium. II. Regulation by GRP and substance P.
Topics: Amiloride; Animals; Biological Transport; Cell Membrane Permeability; Electrolytes; Female; Gastrin-Releasing Peptide; Gastrointestinal Hormones; Ionomycin; Kinetics; Membrane Potentials; Models, Biological; Mucous Membrane; Myometrium; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peptides; Piperidines; Potassium; Substance P; Swine; Thapsigargin | 1997 |
Neurokinin receptors (NK1, NK2) in the mouse: a pharmacological study.
Topics: Animals; In Vitro Techniques; Kinetics; Mice; Mice, Inbred C57BL; Muscle Contraction; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Rabbits; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Stomach; Substance P; Tachykinins; Urinary Bladder | 1997 |
In vitro and in vivo characterization of NK3 receptors in the rabbit eye by use of selective non-peptide NK3 receptor antagonists.
Topics: Animals; In Vitro Techniques; Iris; Male; Miosis; Muscle Contraction; Muscle, Smooth; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Quinolines; Rabbits; Receptors, Neurokinin-3; Substance P | 1997 |
Gly166 in the NK1 receptor regulates tachykinin selectivity and receptor conformation.
Topics: Amino Acid Substitution; Animals; Binding Sites; CHO Cells; COS Cells; Cricetinae; Cysteine; Dithiothreitol; Ethylmaleimide; Glycine; Humans; Kinetics; Mutagenesis, Site-Directed; Neurokinin A; Neurokinin B; Protein Conformation; Rats; Receptors, Neurokinin-1; Receptors, Tachykinin; Recombinant Proteins; Substance P | 1997 |
Cellular pathways mediating tachykinin-evoked secretomotor responses in guinea pig ileum.
Topics: Animals; Capsaicin; Electric Stimulation; Evoked Potentials; Guinea Pigs; Ileum; In Vitro Techniques; Intestinal Mucosa; Membrane Potentials; Muscle, Smooth; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neurons; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Tachykinins | 1997 |
Response of isolated human neurogenic bladders to tachykinins.
Topics: Adolescent; Atropine; Child; Dose-Response Relationship, Drug; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Meningomyelocele; Muscle Contraction; Neurokinin A; Neurokinin B; Sacrococcygeal Region; Substance P; Tachykinins; Urinary Bladder, Neurogenic | 1997 |
Mediation of irregular spiking activity by multiple neurokinin-receptors in the small intestine of the rat.
Topics: Animals; Electromyography; Electrophysiology; Gastrointestinal Motility; Intestine, Small; Male; Myoelectric Complex, Migrating; Neurokinin A; Neurokinin B; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Tachykinins | 1998 |
Tachykinins may modify spontaneous epileptiform activity in the rat entorhinal cortex in vitro by activating GABAergic inhibition.
Topics: Animals; Baclofen; Bicuculline; Entorhinal Cortex; Epilepsy; Evoked Potentials; In Vitro Techniques; Male; Membrane Potentials; Neurokinin A; Neurokinin B; Neurons; Peptide Fragments; Phosphinic Acids; Propanolamines; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Receptors, GABA-B; Substance P; Synapses; Tachykinins | 1998 |
[Tachykinin receptor subtypes involved in endothelium-dependent and -independent responses in rabbit intrapulmonary arteries].
Topics: Animals; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Piperidines; Pulmonary Artery; Rabbits; Receptors, Tachykinin; Substance P | 1997 |
Cultured rat sensory neurones express functional tachykinin receptor subtypes 1, 2 and 3.
Topics: Analysis of Variance; Animals; Cells, Cultured; Ganglia, Spinal; Neurokinin A; Neurokinin B; Neurons, Afferent; Rats; Rats, Wistar; Receptors, Tachykinin; Substance P | 1998 |
Membrane-induced secondary structures of neuropeptides: a comparison of the solution conformations adopted by agonists and antagonists of the mammalian tachykinin NK1 receptor.
Topics: Amino Acid Sequence; Membranes; Micelles; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neuropeptides; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Structure, Secondary; Receptors, Neurokinin-1; Sodium Dodecyl Sulfate; Solutions; Substance P | 1998 |
Changes in tachykinin--ergic nerve terminal densities in rat nasal mucosa during hypersensitivity.
Topics: Animals; Female; Male; Nasal Mucosa; Nerve Endings; Neurokinin A; Neurokinin B; Rats; Rats, Wistar; Rhinitis, Allergic, Perennial; Substance P; Tachykinins; Toluene 2,4-Diisocyanate | 1997 |
Tachykinin receptors are present on human monocytes and play a role in rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Cell Separation; Female; Humans; Male; Middle Aged; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neurokinin A; Neurokinin B; Peptide Fragments; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
[Immunohistochemical study on three peptidergic terminals in nasal mucosa in a rat AR model].
Topics: Animals; Female; Immunohistochemistry; Male; Nasal Mucosa; Neurokinin A; Neurokinin B; Rats; Rats, Wistar; Rhinitis, Allergic, Perennial; Substance P; Tachykinins; Toluene 2,4-Diisocyanate | 1996 |
Tachykinin-depolarizations mediated by neurokinin-3 receptors in the hamster submandibular ganglion cells.
Topics: Animals; Cricetinae; Electric Impedance; Electrophysiology; Ganglia, Parasympathetic; Ion Channels; Membrane Potentials; Neurokinin B; Patch-Clamp Techniques; Peptide Fragments; Potassium Channels; Receptors, Neurokinin-3; Substance P; Tachykinins | 1998 |
High affinity binding sites for [3H]substance P in urinary bladders of cats with interstitial cystitis.
Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Blood Vessels; Brain; Cats; Cystitis, Interstitial; Female; Iodine Radioisotopes; Male; Neurokinin A; Neurokinin B; Pain; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Substrate Specificity; Tritium; Up-Regulation; Urinary Bladder | 1998 |
Distinct modifications by neurokinin1 (SR140333) and neurokinin2 (SR48968) tachykinin receptor antagonists of the N-methyl-D-aspartate-evoked release of acetylcholine in striosomes and matrix of the rat striatum.
Topics: Acetylcholine; Animals; Benzamides; Dopamine; Excitatory Amino Acid Agonists; In Vitro Techniques; Male; N-Methylaspartate; Neostriatum; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-2; Stimulation, Chemical; Substance P | 1998 |
Point mutation increases a form of the NK1 receptor with high affinity for neurokinin A and B and septide.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Neurokinin A; Neurokinin B; Peptide Fragments; Point Mutation; Pyrrolidonecarboxylic Acid; Radioligand Assay; Receptors, Neurokinin-1; Recombinant Proteins; Substance P | 1998 |
Signaling pathways via NK1 receptors and their desensitization in an AR42J cell line.
Topics: Animals; Calcium Signaling; Carcinoma, Acinar Cell; Cyclic AMP; Desensitization, Immunologic; Hydrolysis; Neurokinin A; Neurokinin B; Pancreatic Neoplasms; Phosphatidylinositols; Rats; Receptors, Neurokinin-1; Signal Transduction; Substance P; Tumor Cells, Cultured | 1998 |
Comparative studies on peptides representing the so-called tachykinin-like region of the Alzheimer Abeta peptide [Abeta(25-35)].
Topics: Alzheimer Disease; Amides; Amyloid beta-Peptides; Animals; Circular Dichroism; Eledoisin; Magnetic Resonance Spectroscopy; Neurokinin B; Norleucine; Peptide Fragments; Phenylalanine; Rats; Substance P; Tachykinins | 1998 |
Effect of sensory neuropeptides on mucus secretion from cultured goblet cells.
Topics: Animals; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Exocytosis; Guinea Pigs; Male; Mucus; Neurokinin A; Neurokinin B; Substance P; Trachea | 1998 |
Effects of a tachykinin NK3 receptor antagonist, SR 142801, studied in isolated neonatal rat spinal cord.
Topics: Animals; Animals, Newborn; Capsaicin; Electrophysiology; Female; In Vitro Techniques; Male; Membrane Potentials; Neurokinin B; Neurons, Afferent; Patch-Clamp Techniques; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-3; Spinal Cord; Spinal Nerve Roots; Substance P | 1998 |
Rat gastrointestinal motor responses mediated via activation of neurokinin receptors.
Topics: Animals; Chromates; Chromium Radioisotopes; Gastric Emptying; Gastrointestinal Motility; Intubation, Gastrointestinal; Male; Neurokinin A; Neurokinin B; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Sodium Compounds; Substance P | 1999 |
Substance P and the neurokinins: novel peptide neurotransmitters in psychopharmacology.
Topics: Humans; Neurokinin A; Neurokinin B; Neurotransmitter Agents; Psychotropic Drugs; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Tachykinins; Terminology as Topic | 1999 |
Characterization of [3H]substance P binding sites in human skin.
Topics: Aged; Binding, Competitive; Female; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Middle Aged; Neurokinin A; Neurokinin B; Peptide Fragments; Radioligand Assay; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Skin; Substance P; Tritium | 1999 |
Tachykinin receptors on human monocytes: their involvement in rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Gene Expression; Humans; Male; Middle Aged; Monocytes; Neurokinin A; Neurokinin B; Receptors, Tachykinin; RNA, Messenger; Substance P; Superoxides; Tumor Necrosis Factor-alpha | 1998 |
Neurokinin B- and substance P-like immunoreactivity are co-localized in enteric nerves of rat ileum.
Topics: Animals; Cross Reactions; Enteric Nervous System; Gastric Mucosa; Ileum; Immunohistochemistry; Male; Muscle, Smooth; Neurokinin B; Peptide Fragments; Protein Precursors; Rabbits; Rats; Rats, Sprague-Dawley; Substance P; Tachykinins | 1999 |
The tachykinins neurokinin A and substance P, but not neurokinin B, stimulate contraction of isolated muscle cells from rat small intestine.
Topics: Animals; Dose-Response Relationship, Drug; Gastrointestinal Motility; Intestine, Small; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Smooth; Neurokinin A; Neurokinin B; Rats; Substance P | 1999 |
Differential modulation of human immunoglobulin isotype production by the neuropeptides substance P, NKA and NKB.
Topics: B-Lymphocytes; Cells, Cultured; DNA Primers; Enzyme-Linked Immunosorbent Assay; Epitopes; Gene Expression; Humans; Immunoglobulin A; Immunoglobulin E; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Interleukin-5; Lymphocyte Activation; Mucous Membrane; Neuroimmunomodulation; Neurokinin A; Neurokinin B; Pokeweed Mitogens; Receptors, Neurokinin-1; RNA, Messenger; Sensitivity and Specificity; Substance P; T-Lymphocytes; Tachykinins; Transforming Growth Factor beta | 1999 |
Central tachykinin NK3 receptors in the inhibitory action on the rat colonic propulsion of a new tachykinin, PG-KII.
Topics: Animals; Colon; Gastrointestinal Transit; Injections, Intraventricular; Male; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Tachykinins | 1999 |
The importance of C-terminal residues of vertebrate and invertebrate tachykinins for their contractile activities in gut tissues.
Topics: Amino Acid Substitution; Animals; Arginine; Cockroaches; Guinea Pigs; Helminth Proteins; Male; Methionine; Muscle Contraction; Neurokinin A; Neurokinin B; Neuropeptides; Species Specificity; Substance P | 1999 |
Effects of selective tachykinin-receptor antagonists on tachykinin-induced airway mucus secretion in the rat.
Topics: Animals; Benzamides; Male; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Respiratory Mucosa; Substance P; Tachykinins; Trachea | 1999 |
Tachykinin NK(3)receptor involvement in anxiety.
Topics: Animals; Anxiety; Cerebral Ventricles; Injections, Intraventricular; Male; Maze Learning; Mice; Neurokinin A; Neurokinin B; Peptide Fragments; Piperidines; Receptors, Neurokinin-3; Substance P; Tachykinins | 1999 |
Respiratory actions of tachykinins in the nucleus of the solitary tract: characterization of receptors using selective agonists and antagonists.
Topics: Animals; Benzamides; Indoles; Isoindoles; Male; Microinjections; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Respiratory Mechanics; Solitary Nucleus; Substance P; Tachykinins; Tidal Volume | 2000 |
Respiratory actions of tachykinins in the nucleus of the solitary tract: effect of neonatal capsaicin pretreatment.
Topics: Animals; Animals, Newborn; Capsaicin; Male; Microinjections; Neurokinin A; Neurokinin B; Peptide Fragments; Rats; Rats, Wistar; Respiratory Mechanics; Solitary Nucleus; Substance P; Tachykinins | 2000 |
Immunocytochemical localization of neurokinin B in the rat spinal dorsal horn and its association with substance P and GABA: an electron microscopic study.
Topics: Animals; Axons; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Microscopy, Electron; Neurokinin B; Nociceptors; Pain; Posterior Horn Cells; Rats; Rats, Wistar; Substance P | 2000 |
Neurokinin B- and specific tachykinin NK(3) receptor agonists-induced airway hyperresponsiveness in the guinea-pig.
Topics: Acetylcholine; Animals; Bronchi; Bronchoconstrictor Agents; Female; Guinea Pigs; Male; Neurokinin B; Peptide Fragments; Piperidines; Receptors, Neurokinin-3; Substance P; Tachykinins; Vasodilator Agents | 2000 |
Activation of neurokinin NK(2) receptors by tachykinin peptides causes contraction of uterus in pregnant women near term.
Topics: Adult; Analysis of Variance; Female; Humans; In Vitro Techniques; Neurokinin A; Neurokinin B; Pregnancy; Pregnancy Trimester, Third; Protease Inhibitors; Receptors, Neurokinin-2; Substance P; Tachykinins; Uterine Contraction | 2000 |
[The neurogenic mechanisms of ocular inflammation and their modulation under local treatment with indomethacin].
Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Capillary Permeability; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Indomethacin; Inflammation; Neurokinin A; Neurokinin B; Rabbits; Substance P | 2000 |
Tachykinin-induced contraction of the guinea-pig isolated oesophageal mucosa is mediated by NK(2) receptors.
Topics: Animals; Benzamides; Captopril; Dose-Response Relationship, Drug; Esophagus; Guinea Pigs; In Vitro Techniques; Mucous Membrane; Muscle Contraction; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Protease Inhibitors; Quinolines; Quinuclidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Tachykinins; Thiorphan | 2000 |
Effects of supraspinal administration of PG-SPI and PG-KII, two amphibian tachykinin peptides, on nociception in the rat.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Hot Temperature; Indoles; Male; Naloxone; Narcotic Antagonists; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Oligopeptides; Pain Measurement; Pain Threshold; Piperidines; Pyrrolidonecarboxylic Acid; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Tachykinins; Time Factors | 2000 |
Adaptive plasticity in tachykinin and tachykinin receptor expression after focal cerebral ischemia is differentially linked to gabaergic and glutamatergic cerebrocortical circuits and cerebrovenular endothelium.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Cerebrovascular Circulation; Endothelium, Vascular; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Infarction, Middle Cerebral Artery; Male; Neurokinin B; Neuronal Plasticity; Protein Precursors; Rats; Rats, Long-Evans; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Receptors, Tachykinin; RNA, Messenger; Substance P; Tachykinins; Venules | 2001 |
Effects of natural tachykinins on porcine lower urinary tract smooth muscle.
Topics: Animals; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Swine; Urinary Bladder | 2000 |
Tachykinins contribute to nerve-mediated contractions in the human esophagus.
Topics: Atropine; Autonomic Nervous System; Benzamides; Dose-Response Relationship, Drug; Esophagus; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Parasympatholytics; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Substance P; Tachykinins | 2001 |
Peripheral inflammation reduces the response of spinal dorsal horn neurons to an NK3 receptor agonist.
Topics: Action Potentials; Animals; Carrageenan; Hyperalgesia; Inflammation; Lysine; Neurokinin B; Nociceptors; Pain; Peptide Fragments; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P | 2001 |
Human colonic anti-secretory activity of the potent NK(1) antagonist, SR140333: assessment of potential anti-diarrhoeal activity in food allergy and inflammatory bowel disease.
Topics: Animals; Antidiarrheals; Capsaicin; Colitis, Ulcerative; Colon; Crohn Disease; Epithelial Cells; Food Hypersensitivity; Guinea Pigs; Humans; Immunoglobulin E; Inflammatory Bowel Diseases; Male; Mast Cells; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Rats; Receptors, Neurokinin-1; Species Specificity; Substance P; Tachykinins | 2001 |
C-FOS expression in the rat brain in response to substance P and neurokinin B.
Topics: Analgesics; Animals; Autonomic Nervous System; Behavior, Animal; Brain; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; Immunohistochemistry; Indoles; Isoindoles; Male; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neurons; Neurosecretory Systems; Pain; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Receptors, Tachykinin; Stress, Physiological; Substance P | 2001 |
Neuronal bursting induced by NK3 receptor activation in the neonatal rat spinal cord in vitro.
Topics: Animals; Animals, Newborn; Evoked Potentials; Excitatory Postsynaptic Potentials; In Vitro Techniques; Locomotion; Membrane Potentials; Motor Neurons; Neurokinin B; Neurons; Patch-Clamp Techniques; Peptide Fragments; Rats; Rats, Wistar; Receptors, Neurokinin-3; Spinal Cord; Substance P; Tachyphylaxis | 2001 |
Substance P and neurokinin levels are decreased in the cortex and hypothalamus of alcohol-preferring (P) rats.
Topics: Alcohol Drinking; Animals; Cerebral Cortex; Hypothalamus; Male; Neurokinin A; Neurokinin B; Rats; Species Specificity; Substance P | 2001 |
Biochemical and pharmacological activities of SSR 146977, a new potent nonpeptide tachykinin NK3 receptor antagonist.
Topics: Animals; CHO Cells; Cricetinae; Gerbillinae; Guinea Pigs; Humans; Methylurea Compounds; Motor Activity; Neurokinin B; Peptide Fragments; Piperidines; Rabbits; Rats; Receptors, Neurokinin-3; Substance P | 2002 |
Neurokinin B induces oedema formation in mouse lung via tachykinin receptor-independent mechanisms.
Topics: Animals; Antipsychotic Agents; Benzamides; Cyclooxygenase Inhibitors; Edema; Enzyme Inhibitors; Extravascular Lung Water; Female; Indomethacin; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurokinin B; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Piperidines; Plasma; Pulmonary Edema; Receptors, Neurokinin-1; Substance P | 2002 |
The mechanisms for tachykinin-induced contractions of the rabbit corpus cavernosum.
Topics: Animals; Benzamides; Calcium; Dose-Response Relationship, Drug; Glycopeptides; In Vitro Techniques; Male; Muscle Contraction; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Penis; Permeability; Piperidines; Quinuclidines; Rabbits; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Tachykinins; Type C Phospholipases | 2002 |
Neurokinin-receptor-mediated depolarization of cortical neurons elicits an increase in glutamate release at excitatory synapses.
Topics: Action Potentials; Animals; Entorhinal Cortex; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Interneurons; Male; Neurokinin A; Neurokinin B; Patch-Clamp Techniques; Peptide Fragments; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P; Synapses; Tetrodotoxin | 2002 |
Neurokinin release in the rat nucleus of the solitary tract via NMDA and AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; N-Methylaspartate; Neurokinin A; Neurokinin B; Presynaptic Terminals; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Solitary Nucleus; Substance P; Synaptic Transmission; Vagus Nerve; Visceral Afferents | 2002 |
A tachykinin-like factor increases glutamate toxicity in rat cerebellar granule cells.
Topics: Animals; Antibodies; Cells, Cultured; Cerebellum; Glutamic Acid; Neurokinin A; Neurokinin B; Rats; Rats, Wistar; Receptors, Tachykinin; Substance P; Tachykinins | 2003 |
A role for tachykinins in female mouse and rat reproductive function.
Topics: Animals; Capsaicin; Embryo, Mammalian; Female; Fertility; Gene Expression Regulation; Litter Size; Male; Mice; Neprilysin; Neurokinin A; Neurokinin B; Oocytes; Ovary; Pregnancy; Protein Precursors; Rats; Rats, Wistar; Receptors, Tachykinin; RNA, Messenger; Spermatozoa; Substance P; Tachykinins; Uterus | 2003 |
Diencephalic neurons producing melanin-concentrating hormone are influenced by local and multiple extra-hypothalamic tachykininergic projections through the neurokinin 3 receptor.
Topics: Animals; Brain; Colchicine; Feeding Behavior; Hypothalamic Hormones; Hypothalamus; Interneurons; Male; Melanins; Neural Pathways; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neurons; Organ Culture Techniques; Peptide Fragments; Piperidines; Pituitary Hormones; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-3; RNA, Messenger; Sexual Behavior; Substance P; Tachykinins | 2003 |
Biologic activity of the tachykinins on lamb and sheep gallbladder.
Topics: Animals; Binding Sites; Capsaicin; Dose-Response Relationship, Drug; Female; Gallbladder; Male; Muscles; Neurokinin A; Neurokinin B; Peptide Fragments; Physalaemin; Protein Structure, Tertiary; Pyrrolidonecarboxylic Acid; Receptors, Tachykinin; Sheep; Substance P; Tachykinins | 2003 |
The third intracellular loop and carboxyl tail of neurokinin 1 and 3 receptors determine interactions with beta-arrestins.
Topics: Animals; Arrestins; beta-Arrestin 1; beta-Arrestin 2; beta-Arrestins; Biological Transport; Calcium; Calcium Signaling; Cell Line; Enzyme Activation; Mitogen-Activated Protein Kinases; Neurokinin B; Protein Structure, Tertiary; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Tissue Distribution | 2003 |
Similarities of SP-, NKA- and NKB-induced currents in rat dorsal root ganglion neurons.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Ganglia, Spinal; Membrane Potentials; Neurokinin A; Neurokinin B; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA; Substance P; Tachykinins | 2003 |
Effect of peptidases on the ability of exogenous and endogenous neurokinins to produce neurokinin 1 receptor internalization in the rat spinal cord.
Topics: Aminopeptidases; Animals; Electric Stimulation; Enzyme Inhibitors; Immunohistochemistry; In Vitro Techniques; Microscopy, Confocal; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Spinal Nerve Roots; Substance P | 2003 |
Effects of neuropeptides on the sumatriptan-disturbed circulation in the optic nerve head of rabbits.
Topics: Animals; Arterioles; Blood-Retinal Barrier; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Female; Male; Microinjections; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neuropeptides; Optic Nerve; Peptide Fragments; Rabbits; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Retinal Vessels; Substance P; Sumatriptan; Vasodilation | 2004 |
Leukocyte recruitment to peritoneal cavity of rats following formalin injection: role of tachykinin receptors.
Topics: Animals; Benzamides; Cell Movement; Dose-Response Relationship, Drug; Female; Formaldehyde; Injections, Intraperitoneal; Leukocytes; Models, Biological; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peritoneal Cavity; Peritoneal Lavage; Piperidines; Quinuclidines; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P; Time Factors | 2004 |
Transgenic mice ectopically expressing HOXA5 in the dorsal spinal cord show structural defects of the cervical spinal cord along with sensory and motor defects of the forelimb.
Topics: Animals; Behavior, Animal; Butorphanol; Cell Count; Cloning, Molecular; Embryo, Mammalian; Forelimb; Gene Expression Regulation, Developmental; Homeodomain Proteins; Humans; Immunohistochemistry; In Situ Hybridization; In Situ Nick-End Labeling; Mice; Mice, Knockout; Motor Activity; Narcotics; Neural Pathways; Neurokinin B; Pain; Pain Threshold; Phosphoproteins; Psychomotor Performance; Reaction Time; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensation Disorders; Spinal Cord; Substance P; Transcription Factors | 2004 |
Involvement of enhanced neurokinin NK3 receptor expression in the severe asthma guinea pig model.
Topics: Animals; Asthma; Benzamides; Binding, Competitive; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoconstrictor Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Lung; Male; Methacholine Chloride; Neurokinin B; Ovalbumin; Peptide Fragments; Piperidines; Receptors, Neurokinin-3; Substance P; Tritium | 2004 |
Profiling neurotransmitter receptor expression in mouse gonadotropin-releasing hormone neurons using green fluorescent protein-promoter transgenics and microarrays.
Topics: Animals; Drug Interactions; Female; Galanin; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; Hormone Antagonists; In Situ Hybridization; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurokinin B; Neurons; Oligonucleotide Array Sequence Analysis; Oligopeptides; Patch-Clamp Techniques; Preoptic Area; Receptors, Neurotransmitter; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Somatostatin; Somatostatin-28; Substance P; Tetrodotoxin | 2005 |
Mapping of tachykinins in the cat spinal cord.
Topics: Animals; Antibody Specificity; Brain Mapping; Cats; Cell Shape; Immunohistochemistry; Male; Neurokinin A; Neurokinin B; Neurons; Nociceptors; Pain; Posterior Horn Cells; Presynaptic Terminals; Species Specificity; Spinal Cord; Substance P; Synaptic Transmission; Tachykinins | 2005 |
Involvement of Ca2+ signaling in tachykinin-mediated contractile responses in swine trachea.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Carbachol; Cytosol; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Substance P; Swine; Tachykinins; Trachea | 2005 |
Substance P, neurokinins A and B, and synthetic tachykinin peptides protect mesencephalic dopaminergic neurons in culture via an activity-dependent mechanism.
Topics: Animals; Calcium Channels, N-Type; Cell Count; Cell Survival; Dopamine; Ion Channel Gating; Mesencephalon; Neurokinin A; Neurokinin B; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Sodium Channels; Substance P; Tetrodotoxin | 2005 |
[Effect of natural tachykinins on the bile production in rats].
Topics: Animals; Bile; Bile Acids and Salts; Cholesterol; Liver; Neurokinin A; Neurokinin B; Phospholipids; Rats; Solubility; Substance P; Tachykinins | 2005 |
Characterization of neurons that express preprotachykinin B in the dorsal horn of the rat spinal cord.
Topics: Animals; Calcitonin Gene-Related Peptide; Gene Expression Regulation; Immunohistochemistry; Male; Neurokinin B; Oncogene Proteins v-fos; Phosphopyruvate Hydratase; Physical Stimulation; Posterior Horn Cells; Protein Kinase C; Rats; Rats, Wistar; Receptors, Opioid, mu; Spinal Cord; Substance P; Vesicular Glutamate Transport Protein 2 | 2006 |
Tachykinin receptor expression and function in human esophageal smooth muscle.
Topics: Calcium; Calcium Channels, L-Type; Cell Separation; Cholinergic Agonists; Electrophysiology; Esophagus; Fluorescent Antibody Technique; Humans; Ion Channels; Muscle, Smooth; Neurokinin A; Neurokinin B; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Substance P; Tetrodotoxin | 2006 |
Neurokinin A and neurokinin B in the human retina.
Topics: Chromatography, High Pressure Liquid; Fluorescent Antibody Technique; Humans; Neurokinin A; Neurokinin B; Radioimmunoassay; Retina; Substance P | 2006 |
A role for tachykinins in the regulation of human sperm motility.
Topics: Benzamides; Humans; Immunohistochemistry; Male; Neurokinin A; Neurokinin B; Piperidines; Quinuclidines; Receptors, Tachykinin; Sperm Motility; Spermatozoa; Substance P; Tachykinins | 2007 |
Novel triple neurokinin receptor antagonist CS-003 strongly inhibits neurokinin related responses.
Topics: Animals; Bronchi; Capillary Permeability; Capsaicin; Chlorocebus aethiops; Citric Acid; COS Cells; Cough; Cyclic S-Oxides; Dipeptides; Dose-Response Relationship, Drug; Guinea Pigs; Humans; In Vitro Techniques; Indoles; Inositol Phosphates; Male; Molecular Sequence Data; Morpholines; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Trachea | 2008 |
Tlx1 and Tlx3 coordinate specification of dorsal horn pain-modulatory peptidergic neurons.
Topics: Aging; Animals; Animals, Newborn; Cholecystokinin; Embryo, Mammalian; Gene Expression Regulation; Homeodomain Proteins; Mice; Mice, Transgenic; Mutation; Neurokinin B; Neurons; Neuropeptides; Pain; PAX2 Transcription Factor; Somatostatin; Spinal Cord; Substance P; Transcription Factor Brn-3A; Transcription, Genetic | 2008 |
Gosha-jinki-gan reduces transmitter proteins and sensory receptors associated with C fiber activation induced by acetic acid in rat urinary bladder.
Topics: Acetic Acid; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Immunohistochemistry; Nerve Fibers, Unmyelinated; Neurokinin A; Neurokinin B; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Tachykinins; TRPV Cation Channels; Urinary Bladder; Urinary Bladder, Overactive; Urothelium | 2008 |
Neurokinin 2 receptor-mediated activation of protein kinase C modulates capsaicin responses in DRG neurons from adult rats.
Topics: Age Factors; Animals; Calcium; Capsaicin; Carcinogens; Cells, Cultured; Ganglia, Spinal; Male; Neurokinin A; Neurokinin B; Neurons, Afferent; Nociceptors; Patch-Clamp Techniques; Peptide Fragments; Phorbol Esters; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Sensory System Agents; Signal Transduction; Substance P; TRPV Cation Channels | 2008 |
Menopause and the human hypothalamus: evidence for the role of kisspeptin/neurokinin B neurons in the regulation of estrogen negative feedback.
Topics: Aging; Animals; Dynorphins; Estrogens; Feedback, Physiological; Female; Humans; Hypothalamus; Kisspeptins; Menopause; Middle Aged; Neurokinin B; Neurons; Neurosecretory Systems; Ovary; Rats; Substance P; Tumor Suppressor Proteins | 2009 |
Cryptide signaling: Amphiphilic peptide-induced exocytotic mechanisms in mast cells.
Topics: Animals; Calcium; Calcium Signaling; Cells, Cultured; Exocytosis; GTP-Binding Protein alpha Subunits, Gi-Go; Intercellular Signaling Peptides and Proteins; Mast Cells; Neurokinin A; Neurokinin B; Peptides; Peritoneum; Pertussis Toxin; Rats; Rats, Wistar; Substance P; Wasp Venoms | 2008 |
Localization and function of NK(3) subtype tachykinin receptors of layer V pyramidal neurons of the guinea-pig medial prefrontal cortex.
Topics: Animals; Autoradiography; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Guinea Pigs; In Vitro Techniques; Iodine Isotopes; Male; Membrane Potentials; Neurokinin B; Patch-Clamp Techniques; Peptide Fragments; Prefrontal Cortex; Protein Binding; Pyramidal Cells; Quinolines; Quinoxalines; Receptors, Neurokinin-3; Substance P; Valine | 2008 |
An extract (THC-002) of Ba-Wei-Die-Huang-Wan inhibits expression of tachykinins, and P2X3 and TRPV1 receptors, and inhibits ATP-induced detrusor overactivity in spontaneously hypertensive rats.
Topics: Adenosine Triphosphate; Administration, Oral; Animals; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Female; Hypertension; Immunohistochemistry; Neurokinin A; Neurokinin B; Rats; Rats, Inbred SHR; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Tachykinins; TRPV Cation Channels; Urinary Bladder; Urinary Bladder, Overactive; Urination | 2009 |
Hypogonadotropic hypogonadism due to a novel missense mutation in the first extracellular loop of the neurokinin B receptor.
Topics: Adolescent; Adult; Amenorrhea; Breast; DNA Mutational Analysis; Female; Histidine; Homozygote; Hormones; Humans; Hypogonadism; Leucine; Male; Mutation, Missense; Neurokinin B; Pedigree; Peptide Fragments; Puberty; Receptors, Neurokinin-3; Siblings; Signal Transduction; Substance P | 2009 |
In vitro and in vivo comparison of two non-peptide tachykinin NK3 receptor antagonists: Improvements in efficacy achieved through enhanced brain penetration or altered pharmacological characteristics.
Topics: Aminoquinolines; Animals; Behavior, Animal; Brain; Cerebral Cortex; Cloning, Molecular; Dopamine; Extracellular Space; Guinea Pigs; Habenula; Haloperidol; Humans; Inositol Phosphates; Male; Microdialysis; Neurokinin B; Neurons; Nucleus Accumbens; Peptide Fragments; Peptides; Quinolines; Rats; Receptors, Tachykinin; Substance P | 2010 |
Central administration of substance P inhibits feeding behavior in chicks.
Topics: Animals; Central Nervous System Agents; Chickens; Corticosterone; Corticotropin-Releasing Hormone; Drinking Behavior; Fasting; Feeding Behavior; Male; Motor Activity; Neurokinin A; Neurokinin B; Peptide Fragments; Substance P; Time Factors; Water | 2010 |
Secretoneurin and the tachykinins substance P and neurokinin-A/B in NMDA-induced excitotoxicity in the rat retina.
Topics: Animals; Intravitreal Injections; Male; N-Methylaspartate; Neurokinin A; Neurokinin B; Neuropeptides; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Retina; Secretogranin II; Substance P | 2010 |
Neurokinin B acts via the neurokinin-3 receptor in the retrochiasmatic area to stimulate luteinizing hormone secretion in sheep.
Topics: Anestrus; Animals; Brain; Dopamine; Female; Follicular Phase; Gonadotropin-Releasing Hormone; Injections, Intraventricular; Luteal Phase; Luteinizing Hormone; Models, Biological; Neurokinin B; Neurons; Neurotransmitter Agents; Peptide Fragments; Receptors, Neurokinin-3; Sheep; Substance P | 2010 |
Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Drug Interactions; Gonadotropin-Releasing Hormone; Humans; Immunohistochemistry; Injections, Intravenous; Kisspeptins; Luteinizing Hormone; Macaca mulatta; Male; Microscopy, Confocal; Neurokinin B; Oligopeptides; Orchiectomy; Peptide Fragments; Quinolines; Receptors, G-Protein-Coupled; Receptors, LHRH; Receptors, Neurokinin-3; Substance P | 2010 |
Neurokinin B and kisspeptin: sexual partners or single agents?
Topics: Animals; Arcuate Nucleus of Hypothalamus; Drug Interactions; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Macaca mulatta; Male; Neurokinin B; Oligopeptides; Orchiectomy; Peptide Fragments; Quinolines; Receptors, G-Protein-Coupled; Receptors, Neurokinin-3; Substance P | 2010 |
Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Estradiol; Estrous Cycle; Feedback, Physiological; Female; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Neurons; Organ Specificity; Peptide Fragments; Prosencephalon; Proteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Neurokinin-3; RNA, Messenger; Signal Transduction; Substance P | 2011 |
A galenical of traditional Chinese herbal mixture (THC-002) reduces expression of tachykinin peptides within urethras of spontaneously hypertensive rats.
Topics: Aging; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Hypertension; Male; Models, Animal; Neurokinin A; Neurokinin B; Rats; Rats, Inbred SHR; RNA, Messenger; Sodium Chloride; Substance P; Urethra | 2012 |
Distribution and pharmacological characterization of primate NK-2 tachykinin receptor in the central nervous system of the rhesus monkey.
Topics: Animals; Central Nervous System; CHO Cells; Cricetinae; Humans; Macaca mulatta; Male; Neurokinin A; Neurokinin B; Protein Binding; Receptors, Neurokinin-1; Receptors, Neurokinin-2; RNA, Messenger; Substance P; Transfection | 2011 |
Activation of neurokinin 3 receptors in the median preoptic nucleus decreases core temperature in the rat.
Topics: Animals; Body Temperature; Body Temperature Regulation; Estradiol; Female; Hot Flashes; Neurokinin B; Neurons; Peptide Fragments; Preoptic Area; Proto-Oncogene Proteins c-fos; Rats; Receptors, Neurokinin-3; Substance P | 2011 |
Suppressive effects of glycyrrhetinic acid derivatives on tachykinin receptor activation and hyperalgesia.
Topics: Analgesics; Animals; Calcium; Capsaicin; CHO Cells; Cricetinae; Disease Models, Animal; Formaldehyde; Glycyrrhetinic Acid; Hot Temperature; Humans; Hyperalgesia; Inflammation; Ligation; Male; Neuralgia; Neurokinin A; Neurokinin B; Pain; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Sciatic Nerve; Substance P | 2011 |
Kisspeptin signaling is indispensable for neurokinin B, but not glutamate, stimulation of gonadotropin secretion in mice.
Topics: Adamantane; Animals; Dipeptides; Follicle Stimulating Hormone; Galanin-Like Peptide; Glutamic Acid; Gonadotropin-Releasing Hormone; Gonadotropins; Hypogonadism; Kisspeptins; Luteinizing Hormone; Male; Mice; Mice, Knockout; Models, Neurological; Naltrexone; Neurokinin B; Peptide Fragments; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, N-Methyl-D-Aspartate; Receptors, Neuropeptide; Signal Transduction; Substance P; Testosterone | 2012 |
The inhibitory effects of neurokinin B on GnRH pulse generator frequency in the female rat.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Narcotic Antagonists; Neurokinin B; Ovariectomy; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Receptors, Opioid; Receptors, Opioid, kappa; Signal Transduction; Substance P | 2012 |
Evidence of a role for kisspeptin and neurokinin B in puberty of female sheep.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Female; Gonadotropin-Releasing Hormone; Immunohistochemistry; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Neurons; Oligopeptides; Orchiectomy; Ovariectomy; Peptide Fragments; Receptors, Neurokinin-3; Sexual Maturation; Sheep; Substance P; Time Factors | 2012 |
Expression of selected neuropeptides in pathogenesis of bullous pemphigoid and dermatitis herpetiformis.
Topics: Aged; Aged, 80 and over; Calcitonin Gene-Related Peptide; Corticotropin-Releasing Hormone; Dermatitis Herpetiformis; Female; Humans; Immunohistochemistry; Male; Middle Aged; Neurokinin B; Neuropeptides; Pemphigoid, Bullous; Pruritus; Receptor, Endothelin B; Substance P | 2012 |
A nociceptive signaling role for neuromedin B.
Topics: Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Ganglia, Spinal; Hot Temperature; Immunohistochemistry; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Microarray Analysis; Neuritis; Neurokinin B; Neuropeptides; Nociception; Pain Measurement; Posterior Horn Cells; Receptors, Bombesin; Sensory Receptor Cells; Signal Transduction; Spinal Cord; Substance P | 2012 |
Neurokinin B and the control of the gonadotropic axis in the rat: developmental changes, sexual dimorphism, and regulation by gonadal steroids.
Topics: Androgens; Animals; Arcuate Nucleus of Hypothalamus; Dihydrotestosterone; Estradiol; Estrogens; Female; Luteinizing Hormone; Male; Neurokinin B; Neurons; Peptide Fragments; Rats; Rats, Wistar; Receptors, Neurokinin-3; Sex Characteristics; Sex Factors; Sexual Maturation; Substance P; Testosterone | 2012 |
Suppression of the GnRH pulse generator by neurokinin B involves a κ-opioid receptor-dependent mechanism.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Estradiol; Estrous Cycle; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Neurokinin B; Peptide Fragments; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Substance P | 2012 |
GPR54-dependent stimulation of luteinizing hormone secretion by neurokinin B in prepubertal rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antihypertensive Agents; Bodily Secretions; Female; Kisspeptins; Luteinizing Hormone; Male; Naltrexone; Narcotic Antagonists; Neurokinin B; Peptide Fragments; Radioimmunoassay; Rats; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Tachykinin; Substance P | 2012 |
Electrophysiological and morphological evidence for synchronized GnRH pulse generator activity among Kisspeptin/neurokinin B/dynorphin A (KNDy) neurons in goats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Axons; Dynorphins; Electrodes; Electrophysiological Phenomena; Female; Gene Expression Regulation, Developmental; Goats; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Neurokinin B; Neurons; Peptide Fragments; Pheromones; Substance P | 2013 |
Neurogenic airway inflammation induced by repeated intra-esophageal instillation of HCl in guinea pigs.
Topics: Animals; Bronchi; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Esophagus; Guinea Pigs; Hydrochloric Acid; Lung; Neurogenic Inflammation; Neurokinin A; Neurokinin B; Neuropeptides; Nodose Ganglion; Pneumonia; Respiratory System; Substance P; Trachea | 2013 |
Neurokinin B causes acute GnRH secretion and repression of GnRH transcription in GT1-7 GnRH neurons.
Topics: Animals; Base Pairing; Binding Sites; Cell Line; Chromatin Assembly and Disassembly; Enhancer Elements, Genetic; Gonadotropin-Releasing Hormone; Humans; Mice; Neurokinin B; Neurons; Peptide Fragments; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-fos; Rats; Receptors, Neurokinin-3; Sequence Deletion; Substance P; Time Factors; Transcription Factor AP-1; Transcription, Genetic | 2013 |
Interactions between kisspeptins and neurokinin B.
Topics: Animals; Dynorphins; gamma-Aminobutyric Acid; Glutamic Acid; Gonadal Steroid Hormones; Humans; Kisspeptins; Luteinizing Hormone; Mutation; Neurokinin B; Neurons; Peptide Fragments; Puberty; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Rodentia; Sexual Maturation; Substance P | 2013 |
Neurokinin B activates arcuate kisspeptin neurons through multiple tachykinin receptors in the male mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Green Fluorescent Proteins; Kisspeptins; Male; Membrane Potentials; Mice; Mice, Transgenic; Neurokinin B; Neurons; Oligopeptides; Patch-Clamp Techniques; Peptide Fragments; Piperidines; Quinolines; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Receptors, Tachykinin; Substance P | 2013 |
Regulation of arcuate neurons coexpressing kisspeptin, neurokinin B, and dynorphin by modulators of neurokinin 3 and κ-opioid receptors in adult male mice.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Benzeneacetamides; Dynorphins; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; Kisspeptins; Male; Membrane Potentials; Mice; Mice, Transgenic; Neurokinin B; Neurons; Orchiectomy; Peptide Fragments; Pyrrolidines; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Substance P; Time Factors | 2013 |
Chronic peripheral administration of kappa-opioid receptor antagonist advances puberty onset associated with acceleration of pulsatile luteinizing hormone secretion in female rats.
Topics: Animals; Drug Implants; Dynorphins; Female; Luteinizing Hormone; Naltrexone; Narcotic Antagonists; Nerve Tissue Proteins; Neurokinin B; Neurons; Ovary; Peptide Fragments; Puberty, Precocious; Random Allocation; Rats; Rats, Wistar; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Sexual Maturation; Signal Transduction; Substance P; Weaning | 2013 |
Substance P immunoreactivity exhibits frequent colocalization with kisspeptin and neurokinin B in the human infundibular region.
Topics: Adult; Aged; Aged, 80 and over; Arcuate Nucleus of Hypothalamus; Axons; Capillaries; Cell Body; Female; Fluorescent Antibody Technique; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Male; Middle Aged; Neurokinin B; Pituitary Gland; Protein Transport; Substance P; Young Adult | 2013 |
Nicotine enhances excitability of medial habenular neurons via facilitation of neurokinin signaling.
Topics: Action Potentials; Animals; Female; Habenula; Male; Mice; Mice, Inbred C57BL; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neurons; Nicotine; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Receptors, Nicotinic; Signal Transduction; Substance P; Substance Withdrawal Syndrome | 2014 |
Neurokinin B signaling in the female rat: a novel link between stress and reproduction.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arcuate Nucleus of Hypothalamus; Corticosterone; Corticotropin-Releasing Hormone; Female; Gonadotropin-Releasing Hormone; Injections, Intraventricular; Lipopolysaccharides; Luteinizing Hormone; Neurokinin B; Neurons; Ovariectomy; Peptide Fragments; Pyrimidines; Pyrroles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Receptors, Neurokinin-3; Receptors, Vasopressin; Reproduction; Signal Transduction; Stress, Physiological; Substance P | 2014 |
Effects of Qufeng Xuanfei decoction in animal model of post-infectious cough.
Topics: Animals; Bronchoalveolar Lavage; Calcitonin Gene-Related Peptide; Cell Count; Cough; Disease Models, Animal; Drugs, Chinese Herbal; Infections; Lung; Male; Neurokinin A; Neurokinin B; Rats; Rats, Sprague-Dawley; Substance P | 2014 |
Colocalization of cocaine- and amphetamine-regulated transcript with kisspeptin and neurokinin B in the human infundibular region.
Topics: Aged; Aged, 80 and over; Agouti-Related Protein; Axons; Female; Fluorescent Antibody Technique; Gonadotropin-Releasing Hormone; Humans; Kisspeptins; Middle Aged; Nerve Tissue Proteins; Neurokinin B; Pituitary Gland; Protein Transport; Substance P | 2014 |
Development of novel neurokinin 3 receptor (NK3R) selective agonists with resistance to proteolytic degradation.
Topics: Animals; Female; Goats; Humans; Hypothalamus; Inhibitory Concentration 50; Neurokinin B; Ovariectomy; Peptide Fragments; Peptide Hydrolases; Peptidomimetics; Protein Stability; Receptors, Neurokinin-3; Serum; Substance P; Swine | 2014 |
Hypophysiotropic gonadotropin-releasing hormone projections are exposed to dense plexuses of kisspeptin, neurokinin B and substance p immunoreactive fibers in the human: a study on tissues from postmenopausal women.
Topics: Aged; Aged, 80 and over; Axons; Female; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Immunohistochemistry; Kisspeptins; Middle Aged; Neurokinin B; Neurons; Pituitary Gland; Postmenopause; Substance P | 2014 |
Effects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult rats.
Topics: Aging; Animals; Dynorphins; Enkephalins; Female; Follicle Stimulating Hormone; Hypothalamus; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Peptide Fragments; Protein Precursors; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 2015 |
Evidence that Neurokinin B Controls Basal Gonadotropin-Releasing Hormone Secretion but Is Not Critical for Estrogen-Positive Feedback in Sheep.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Estrogens; Estrous Cycle; Female; Gonadotropin-Releasing Hormone; Immunohistochemistry; In Situ Hybridization; Kisspeptins; Luteinizing Hormone; Models, Animal; Neurokinin B; Neurons; Neurotransmitter Agents; Ovariectomy; Peptide Fragments; Receptors, Neurokinin-3; RNA, Messenger; Sheep; Substance P | 2015 |
Analysis of the Expression of Tachykinins and Tachykinin Receptors in the Rat Uterus During Early Pregnancy.
Topics: Animals; Decidua; Embryo Implantation; Female; Litter Size; Neurokinin B; Pregnancy; Proestrus; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P; Tachykinins; Uterus | 2015 |
Both Estrogen and Androgen Modify the Response to Activation of Neurokinin-3 and κ-Opioid Receptors in Arcuate Kisspeptin Neurons From Male Mice.
Topics: Androgens; Animals; Arcuate Nucleus of Hypothalamus; Dihydrotestosterone; Dynorphins; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Mice; Neurokinin B; Neurons; Orchiectomy; Patch-Clamp Techniques; Peptide Fragments; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Receptors, Steroid; Substance P | 2016 |
A Direct Neurokinin B Projection from the Arcuate Nucleus Regulates Magnocellular Vasopressin Cells of the Supraoptic Nucleus.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Infusions, Intraventricular; Kisspeptins; Male; Mice; Mice, Transgenic; Neuroanatomical Tract-Tracing Techniques; Neurokinin B; Neurons; Oxytocin; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Receptors, Neurokinin-3; Substance P; Supraoptic Nucleus; Vasopressins | 2016 |
Do Substance P and Neurokinin A Play Important Roles in the Control of LH Secretion in Ewes?
Topics: Animals; Dose-Response Relationship, Drug; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Immunohistochemistry; Kisspeptins; Luteinizing Hormone; Neurokinin A; Neurokinin B; Neurons; Receptors, Neurokinin-1; Sheep; Signal Transduction; Substance P | 2016 |
Evidence of involvement of neurone-glia/neurone-neurone communications via gap junctions in synchronised activity of KNDy neurones.
Topics: Animals; Cells, Cultured; Connexins; Dynorphins; Gap Junctions; Glycyrrhetinic Acid; Kisspeptins; Medulla Oblongata; Mefloquine; Mice, Transgenic; Neuroglia; Neurokinin B; Neurons; Peptide Fragments; Substance P | 2017 |
Kisspeptin and Neurokinin B Signaling Network Underlies the Pubertal Increase in GnRH Release in Female Rhesus Monkeys.
Topics: Animals; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Macaca mulatta; Median Eminence; Neurokinin B; Neurons; Peptide Fragments; Quinolines; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Sexual Maturation; Signal Transduction; Substance P | 2017 |
Neurokinin B receptor agonist and Dynorphin receptor antagonist stimulated luteinizing hormone secretion in fasted male rodents.
Topics: Animals; Fasting; Luteinizing Hormone; Male; Naltrexone; Narcotic Antagonists; Neurokinin B; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Receptors, Opioid; Signal Transduction; Substance P | 2018 |
Hypothalamic Reproductive Endocrine Pulse Generator Activity Independent of Neurokinin B and Dynorphin Signaling.
Topics: Academic Medical Centers; Adolescent; Adult; Animals; Case-Control Studies; Child; Disease Models, Animal; Dynorphins; Female; Gonadotropin-Releasing Hormone; Humans; Hypogonadism; Kisspeptins; Luteinizing Hormone; Mice; Mice, Knockout; Narcotic Antagonists; Neurokinin B; Neurons; Signal Transduction; Substance P; Treatment Outcome; Young Adult | 2019 |
Characterization of the Role of NKA in the Control of Puberty Onset and Gonadotropin Release in the Female Mouse.
Topics: Animals; Female; Gonadotropins; Kisspeptins; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurokinin A; Neurokinin B; Protein Precursors; Receptors, Neurokinin-2; Sexual Maturation; Substance P; Tachykinins | 2019 |
Regulation of prepubertal dynorphin secretion in the medial basal hypothalamus of the female rat.
Topics: Animals; Dynorphins; Female; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Insulin-Like Growth Factor I; Microinjections; Neurokinin B; Peptide Fragments; Peptides; Rats; Receptor, IGF Type 1; Receptors, Neurokinin-3; Receptors, Opioid; Sexual Maturation; Substance P; Up-Regulation | 2019 |
Role for Kisspeptin and Neurokinin B in Regulation of Luteinizing Hormone and Testosterone Secretion in the Fetal Sheep.
Topics: Animals; Female; Fetus; Gonadotropin-Releasing Hormone; Hypothalamus; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Oligopeptides; Peptide Fragments; Pregnancy; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Sheep; Substance P; Testosterone | 2020 |
Effects of inhalation of sevoflurane at different concentrations on TRPV1 in airways of rats at different developmental stages.
Topics: Administration, Inhalation; Age Factors; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Body Weight; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Neurokinin A; Neurokinin B; Rats; Rats, Sprague-Dawley; Respiration; Sevoflurane; Substance P; Trachea; TRPV Cation Channels | 2020 |
Neurokinin 3 receptor-selective agonist, senktide, decreases core temperature in Japanese Black cattle.
Topics: Animals; Body Temperature; Body Temperature Regulation; Cattle; Female; Gonadotropin-Releasing Hormone; Heat-Shock Response; Luteinizing Hormone; Neurokinin B; Ovary; Peptide Fragments; Receptors, Neurokinin-3; Signal Transduction; Substance P; Vagina | 2021 |
Influence of acupuncture on the expression of VIP, SP, NKA and NKB, cAMP/cGMP and HE content and treatment of bronchial asthma in rats.
Topics: Acupuncture Therapy; Animals; Asthma; Cyclic AMP; Cyclic GMP; Immunohistochemistry; Inflammation Mediators; Lung; Male; Neurokinin B; Rats; Rats, Wistar; Substance P; Vasoactive Intestinal Peptide | 2020 |
Ionic signalling mechanisms involved in neurokinin-3 receptor-mediated augmentation of fear-potentiated startle response in the basolateral amygdala.
Topics: Animals; Basolateral Nuclear Complex; Fear; Mice; Neurokinin A; Neurokinin B; Phosphatidylinositols; Phospholipases; Protein Kinase C; Rats; Receptors, Neurokinin-3; Reflex, Startle; Substance P; TRPC Cation Channels | 2022 |