Page last updated: 2024-08-23

substance p and l 733060

substance p has been researched along with l 733060 in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (2.38)	18.2507
2000's	18 (42.86)	29.6817
2010's	20 (47.62)	24.3611
2020's	3 (7.14)	2.80

Authors

Authors	Studies
Boyce, S; Carlson, E; Hill, RG; Rupniak, NMJ; Webb, JK	1
Carlson, EC; de Felipe, C; Harrison, T; Hunt, S; Oates, B; Owen, S; Rupniak, NM; Seward, E; Wheeldon, A	1
Bredesen, DE; Castro-Obregón, S; Chen, SF; Del Rio, G; Frankowski, H; Nicholls, DG; Rao, RV; Stoka, V; Swanson, RA; Vesce, S	1
Angulo, JA; Cadet, JL; Yu, J	1
Jang, JH; Leem, JW; Nam, TS; Paik, KS	1
Castro, E; Coveñas, R; Muñoz, M; Pérez, A; Rosso, M	1
Guo, ZQ; Huang, PQ; Liu, LX; Ruan, YP	1
Charette, AB; Grenon, M; Lemire, A; Pourashraf, M	1
Fiebich, BL; Heinen, M; Herpfer, I; Kupferschmid, S; Langosch, JM; Lieb, K; Walden, J	1
Coveñas, R; Muñoz, M; Pérez, A; Piruat, JI; Rosso, M; Rosso, R; Zamarriego, C	1
Coveñas, R; Montero, I; Muñoz, M; Pérez, A; Rosso, M; Rosso, R; Soult, JA; Zamarriego, C	1
Fiebich, BL; Hamke, M; Herpfer, I; Lieb, K; Wandelt, C	1
Budai, D; Khasabov, SG; Mantyh, PW; Simone, DA	1
Coveñas, R; González-Moles, MA; Montero, I; Muñoz, M; Robles, MJ; Rosso, M	1
Inoue, T; Ishikawa, T; Kamei, C; Ohtsu, H; Rahman, MA; Yatsuzuka, R	1
Aguilar, FJ; Esteban, F; González-Moles, MA; Muñoz, M; Redondo, M; Rosso, M	1
Kamei, C; Kuyama, S; Ogawa, M; Yokota, E	1
Coveñas, R; Muñoz, M; Robles-Frías, MJ; Rosso, M; Salinas-Martín, MV	1
Dolber, PC; Douglas, KL; Eldaif, BM; Fraser, MO; Jin, H; Nassar, R; Zhang, X	1
Hamity, MV; Hammond, DL; White, SR	1
Alysandratos, KD; Angelidou, A; Asadi, S; Conti, P; Kalogeromitros, D; Kempuraj, D; Leeman, S; Peterson, E; Stavrianeas, N; Tagen, M; Theoharides, TC; Vasiadi, M; Zhang, B	1
Coveñas, R; González-Ortega, A; Muñoz, M	1
Almendro, V; Ametller, E; Casas, I; Fernández-Nogueira, P; García-Recio, S; Gascón, P; Mayordomo, C; Pastor-Arroyo, EM; Vinyals, L	1
Coveñas, R; Rodriguez, FD	1
Fish, EW; Heilig, M; Krouse, MC; Malanga, CJ; Robinson, JE; Thorsell, A	1
Henry, PJ; Mann, TS; Taylor, SJ	1
Aricò, G; Parenti, C; Ronsisvalle, G; Scoto, GM	1
Thornton, E; Vink, R	1
Wang, DH; Wang, Y	1
Carranza, A; Coveñas, R; González-Ortega, A; Muñoz, M; Robles-Frias, MJ; Rosso, M; Salinas-Martín, MV	1
Akiyama, T; Carstens, E; Carstens, MI; Takamori, K; Tominaga, M	1
Almendro, V; Carranza, A; Coveñas, R; Garcia-Recio, S; González-Ortega, A; Muñoz, M; Salinas-Martín, MV	1
Dong, J; Feng, F; Hong, L; Xu, G; Yang, J; Zhang, H	1
Ding, D; Hu, JL; Liu, XP; Ren, H; Wang, JG; Yang, WL; Yu, J; Zhang, L	1
Chang, C; Ling, J; Lv, B; Ping, F; Qian, J; Shang, J; Song, H; Wang, L; Wang, Y; Zhou, J	1
Alevizos, M; Conti, P; Karagkouni, A; Leeman, SE; Norwitz, E; Taracanova, A; Theoharides, TC; Weng, Z	1
Bing, G; Byun, JK; Dang, DK; Hong, JS; Jang, CG; Jeong, JH; Kim, DJ; Kim, HC; Ko, SK; Nah, SY; Shin, EJ; Tran, HQ	1
He, F; Li, Q; Luo, C; Tao, L; Wu, X; Xu, X; Yang, Y; Zhang, Y; Zhang, Z	1
Bonci, A; Demarest, TG; Francis, TC; Shen, H; Yano, H	1
Hatano, M; Kimura, K; Nishida, T; Uchi, SH; Yamada, N; Yanai, R	1
Favila, N; Gurney, K; Overton, PG	2

Reviews

1 review(s) available for substance p and l 733060

Article	Year
Targeting opioid and neurokinin-1 receptors to treat alcoholism. Current medicinal chemistry, 2011, Volume: 18, Issue:28 Topics: Alcoholism; Animals; Humans; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Opioid Peptides; Piperidines; Receptors, Neurokinin-1; Receptors, Opioid; Substance P	2011

Other Studies

41 other study(ies) available for substance p and l 733060

Article	Year
Enantioselective inhibition of the formalin paw late phase by the NK1 receptor antagonist L-733,060 in gerbils. Pain, 1996, Volume: 67, Issue:1 Topics: Animals; Female; Foot; Formaldehyde; Gerbillinae; Injections; Male; Motor Activity; Neurokinin-1 Receptor Antagonists; Nociceptors; Peptide Fragments; Piperidines; Stereoisomerism; Substance P; Time Factors	1996
Pharmacological blockade or genetic deletion of substance P (NK(1)) receptors attenuates neonatal vocalisation in guinea-pigs and mice. Neuropharmacology, 2000, Jun-08, Volume: 39, Issue:8 Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Buspirone; Diazepam; Dose-Response Relationship, Drug; Female; Fluoxetine; Gene Deletion; Guinea Pigs; Imipramine; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Motor Activity; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Social Isolation; Stress, Psychological; Substance P; Tetrazoles; Vocalization, Animal	2000
A ligand-receptor pair that triggers a non-apoptotic form of programmed cell death. Cell death and differentiation, 2002, Volume: 9, Issue:8 Topics: Animals; Annexin A5; Apoptosis; Caspase Inhibitors; Caspases; Cell Size; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Fetus; Humans; Immunohistochemistry; Kidney; Microscopy, Electron; Neurokinin-1 Receptor Antagonists; Neurons; Piperidines; Prosencephalon; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Tryptophan	2002
Neurokinin-1 (NK-1) receptor antagonists abrogate methamphetamine-induced striatal dopaminergic neurotoxicity in the murine brain. Journal of neurochemistry, 2002, Volume: 83, Issue:3 Topics: Androstanes; Animals; Autoradiography; Benzimidazoles; Binding Sites; Brain; Brain Chemistry; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fever; Glial Fibrillary Acidic Protein; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Neurokinin-1 Receptor Antagonists; Neuroprotective Agents; Piperidines; Signal Transduction; Substance P; Tyrosine 3-Monooxygenase	2002
Involvement of peripherally released substance P and calcitonin gene-related peptide in mediating mechanical hyperalgesia in a traumatic neuropathy model of the rat. Neuroscience letters, 2004, Apr-29, Volume: 360, Issue:3 Topics: Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Disease Models, Animal; Functional Laterality; Hyperalgesia; Lumbosacral Region; Male; Pain Measurement; Pain Threshold; Peptide Fragments; Piperidines; Rats; Rats, Sprague-Dawley; Rhizotomy; Spinal Cord Injuries; Statistics, Nonparametric; Substance P; Time Factors	2004
Antitumoural action of L-733,060 on neuroblastoma and glioma cell lines. Archives italiennes de biologie, 2004, Volume: 142, Issue:2 Topics: Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Glioma; Humans; Neuroblastoma; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Substance P	2004
A general approach to (5S,6R)-6-alkyl-5-benzyloxy-2-piperidinones: application to the asymmetric syntheses of neurokinin substance P receptor antagonist (-)-L-733,061 and (-)-deoxocassine. The Journal of organic chemistry, 2004, Sep-03, Volume: 69, Issue:18 Topics: Catalysis; Combinatorial Chemistry Techniques; HIV Protease Inhibitors; Molecular Structure; Neurokinin-1 Receptor Antagonists; Piperidines; Stereoisomerism; Substance P	2004
Nucleophilic addition to 3-substituted pyridinium salts: expedient syntheses of (-)-L-733,061 and (-)-CP-99,994. Organic letters, 2004, Sep-30, Volume: 6, Issue:20 Topics: Molecular Structure; Piperidines; Pyridinium Compounds; Stereoisomerism; Structure-Activity Relationship; Substance P	2004
Effects of substance P and its antagonist L-733060 on long term potentiation in guinea pig hippocampal slices. Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Neurokinin-1 Receptor Antagonists; Piperidines; Substance P; Time Factors	2005
The NK1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on neuroblastoma and glioma cell lines. Neuropeptides, 2005, Volume: 39, Issue:4 Topics: Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line, Tumor; Glioma; Humans; Mitogens; Neuroblastoma; Piperidines; Receptors, Neurokinin-1; Substance P	2005
Antitumoral action of the neurokinin-1-receptor antagonist L-733,060 and mitogenic action of substance P on human retinoblastoma cell lines. Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:7 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Mitogens; Neurokinin-1 Receptor Antagonists; Piperidines; Retinal Neoplasms; Retinoblastoma; Substance P; Tetrazolium Salts	2005
Substance P induces expression of the corticotropin-releasing factor receptor 1 by activation of the neurokinin-1 receptor. Brain research, 2006, Aug-02, Volume: 1102, Issue:1 Topics: Animals; Animals, Newborn; Astrocytes; Astrocytoma; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Neurokinin-1 Receptor Antagonists; Oligonucleotide Array Sequence Analysis; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Time Factors	2006
NK-1 receptors modulate the excitability of ON cells in the rostral ventromedial medulla. Journal of neurophysiology, 2007, Volume: 97, Issue:2 Topics: Animals; Capsaicin; Electrophysiology; Excitatory Amino Acid Agonists; Extracellular Space; Immunohistochemistry; Iontophoresis; Male; Medulla Oblongata; Microscopy, Confocal; N-Methylaspartate; Neurons; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P	2007
Neurokinin-1 receptors located in human retinoblastoma cell lines: antitumor action of its antagonist, L-732,138. Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:6 Topics: Apoptosis; Blotting, Western; Cell Count; Cell Proliferation; Child, Preschool; Dose-Response Relationship, Drug; Humans; Immunoenzyme Techniques; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Retinal Neoplasms; Retinoblastoma; Stereoisomerism; Substance P; Tryptophan; Tumor Cells, Cultured	2007
Involvement of chemical mediators in nasal allergic responses of HDC-KO mice. European journal of pharmacology, 2007, Jul-19, Volume: 567, Issue:3 Topics: Animals; Behavior, Animal; Chlorpheniramine; Histamine H1 Antagonists; Histidine Decarboxylase; Hydantoins; Immunization; Immunoglobulin E; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Ovalbumin; Piperidines; Receptors, Immunologic; Receptors, Prostaglandin; Rhinitis, Allergic, Seasonal; Sneezing; Substance P	2007
NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human laryngeal cancer cell line HEp-2. Investigational new drugs, 2008, Volume: 26, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Humans; Laryngeal Neoplasms; Mitosis; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Substance P; Tryptophan	2008
Substance P is involved in the effect of histamine H3 receptor agonist, Sch 50971 on nasal allergic symptoms in mice. International immunopharmacology, 2008, Volume: 8, Issue:8 Topics: Animals; Capsaicin; Cetirizine; Disease Models, Animal; Female; Histamine; Histamine Agonists; Histamine H1 Antagonists, Non-Sedating; Imidazoles; Mice; Mice, Inbred BALB C; Ovalbumin; Piperidines; Pyrrolidines; Receptors, Histamine H3; Rhinitis, Allergic, Perennial; Substance P; Thiourea	2008
The NK-1 receptor is expressed in human primary gastric and colon adenocarcinomas and is involved in the antitumor action of L-733,060 and the mitogenic action of substance P on human gastrointestinal cancer cell lines. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2008, Volume: 29, Issue:4 Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, Drug; Humans; Immunohistochemistry; Mitogens; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Stomach Neoplasms; Substance P	2008
Sprouting of substance P-expressing primary afferent central terminals and spinal micturition reflex NK1 receptor dependence after spinal cord injury. American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:6 Topics: Animals; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Electromyography; Female; Injections, Spinal; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Piperidines; Pressure; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Reflex; Spinal Cord Ischemia; Spinal Nerves; Substance P; Time Factors; Urinary Bladder; Urination	2008
Effects of neurokinin-1 receptor agonism and antagonism in the rostral ventromedial medulla of rats with acute or persistent inflammatory nociception. Neuroscience, 2010, Feb-03, Volume: 165, Issue:3 Topics: Animals; Capsaicin; Central Nervous System Agents; Freund's Adjuvant; Hot Temperature; Male; Medulla Oblongata; Mustard Plant; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Piperidines; Plant Oils; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Time Factors	2010
IL-33 augments substance P-induced VEGF secretion from human mast cells and is increased in psoriatic skin. Proceedings of the National Academy of Sciences of the United States of America, 2010, Mar-02, Volume: 107, Issue:9 Topics: Calcium; Cytosol; Humans; Immunohistochemistry; Interleukin-33; Interleukins; Mast Cells; Neurokinin-1 Receptor Antagonists; Piperidines; Psoriasis; RNA, Messenger; Skin; Substance P; Vascular Endothelial Growth Factor A	2010
The NK-1 receptor is expressed in human leukemia and is involved in the antitumor action of aprepitant and other NK-1 receptor antagonists on acute lymphoblastic leukemia cell lines. Investigational new drugs, 2012, Volume: 30, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Aprepitant; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Child; Dose-Response Relationship, Drug; Female; Humans; Inhibitory Concentration 50; Morpholines; Neurokinin-1 Receptor Antagonists; Piperidines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Real-Time Polymerase Chain Reaction; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Substance P; Tryptophan	2012
Targeting of substance P induces cancer cell death and decreases the steady state of EGFR and Her2. Journal of cellular physiology, 2012, Volume: 227, Issue:4 Topics: Antibodies; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Female; Humans; Lapatinib; Ligands; Male; Neoplasms; Neurokinin-1 Receptor Antagonists; Piperidines; Prostatic Neoplasms; Quinazolines; Receptor, ErbB-2; Receptors, Neurokinin-1; Signal Transduction; Substance P; Trastuzumab	2012
Potentiation of brain stimulation reward by morphine: effects of neurokinin-1 receptor antagonism. Psychopharmacology, 2012, Volume: 220, Issue:1 Topics: Analgesics, Opioid; Animals; Brain; Dose-Response Relationship, Drug; Electric Stimulation; Male; Mice; Mice, Inbred C57BL; Morphine; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Reinforcement, Psychology; Reward; Substance P	2012
Influence of influenza A infection on capsaicin-induced responses in murine airways. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2 Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Inflammation; Influenza A virus; Isoproterenol; Leukocytes; Male; Mice; Mice, Inbred BALB C; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Orthomyxoviridae Infections; Piperidines; Prostaglandin Antagonists; Respiratory Mucosa; Specific Pathogen-Free Organisms; Substance P; Trachea; TRPV Cation Channels; Xanthones	2012
Supraspinal injection of Substance P attenuates allodynia and hyperalgesia in a rat model of inflammatory pain. Peptides, 2012, Volume: 34, Issue:2 Topics: Animals; Carrageenan; Dose-Response Relationship, Drug; Hyperalgesia; Infusions, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Naloxone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Nociception; Pain; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P	2012
Treatment with a substance P receptor antagonist is neuroprotective in the intrastriatal 6-hydroxydopamine model of early Parkinson's disease. PloS one, 2012, Volume: 7, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Blood-Brain Barrier; Cells; Dopaminergic Neurons; Inflammation; Male; Motor Activity; Neurokinin-1 Receptor Antagonists; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Piperidines; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Substance P; Substantia Nigra; Tryptophan	2012
Role of substance P in renal injury during DOCA-salt hypertension. Endocrinology, 2012, Volume: 153, Issue:12 Topics: Animals; Blood Pressure; Desoxycorticosterone; Hydroxyproline; Hypertension; Isoindoles; Kidney; Male; Mice; Mice, Inbred C57BL; Piperidines; Receptors, Neurokinin-1; Substance P; Telemetry; Time Factors	2012
The substance P/neurokinin-1 receptor system in lung cancer: focus on the antitumor action of neurokinin-1 receptor antagonists. Peptides, 2012, Volume: 38, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Aprepitant; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Morpholines; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Structure-Activity Relationship; Substance P; Tryptophan; Tumor Cells, Cultured	2012
Roles of glutamate, substance P, and gastrin-releasing peptide as spinal neurotransmitters of histaminergic and nonhistaminergic itch. Pain, 2014, Volume: 155, Issue:1 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Antirheumatic Agents; Bombesin; Chloroquine; Drug Combinations; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Gastrin-Releasing Peptide; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Neurons; Peptide Fragments; Piperidines; Pruritus; Substance P; Vesicular Glutamate Transport Protein 2	2014
The neurokinin-1 receptor antagonist aprepitant is a promising candidate for the treatment of breast cancer. International journal of oncology, 2014, Volume: 45, Issue:4 Topics: Antineoplastic Agents; Aprepitant; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; MCF-7 Cells; Morpholines; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Substance P; Tryptophan	2014
Elevated SP/NK-1R in esophageal carcinoma promotes esophageal carcinoma cell proliferation and migration. Gene, 2015, Apr-15, Volume: 560, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Calcium Channel Blockers; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Esophageal Neoplasms; Female; Humans; Imidazoles; Lymphatic Metastasis; Male; Mice, Nude; Middle Aged; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Substance P; Xenograft Model Antitumor Assays	2015
Neurokinin-1 activation affects EGFR related signal transduction in triple negative breast cancer. Cellular signalling, 2015, Volume: 27, Issue:7 Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cetuximab; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Middle Aged; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Receptors, Neurokinin-1; RNA Interference; RNA, Small Interfering; Signal Transduction; Substance P; Triple Negative Breast Neoplasms	2015
Neurokinin-1 receptor is a novel positive regulator of Wnt/ β-catenin signaling in melanogenesis. Oncotarget, 2016, Dec-06, Volume: 7, Issue:49 Topics: Animals; beta Catenin; Cells, Cultured; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3 beta; Humans; Intercellular Signaling Peptides and Proteins; Melanins; Melanocytes; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Phosphorylation; Piperidines; Receptors, Neurokinin-1; Skin; Skin Pigmentation; Substance P; Time Factors; Wnt Signaling Pathway	2016
SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors. Proceedings of the National Academy of Sciences of the United States of America, 2017, 05-16, Volume: 114, Issue:20 Topics: Biphenyl Compounds; Cell Line, Tumor; Humans; Interleukin-1 Receptor-Like 1 Protein; Interleukin-33; Luteolin; MAP Kinase Signaling System; Mast Cells; NF-kappa B; Piperidines; Receptors, Neurokinin-1; Substance P; Tumor Necrosis Factor-alpha	2017
Ginsenoside Re protects methamphetamine-induced dopaminergic neurotoxicity in mice via upregulation of dynorphin-mediated κ-opioid receptor and downregulation of substance P-mediated neurokinin 1 receptor. Journal of neuroinflammation, 2018, Feb-21, Volume: 15, Issue:1 Topics: Animals; Dopamine; Dopaminergic Neurons; Dynorphins; Ginsenosides; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Piperidines; Reactive Oxygen Species; Receptors, Neurokinin-1; Receptors, Opioid, kappa; Substance P; Up-Regulation	2018
Tachykinin NK1 receptor antagonist L-733,060 and substance P deletion exert neuroprotection through inhibiting oxidative stress and cell death after traumatic brain injury in mice. The international journal of biochemistry & cell biology, 2019, Volume: 107 Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Injuries, Traumatic; Gene Expression Regulation; Gene Knockout Techniques; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Motor Activity; Neurokinin-1 Receptor Antagonists; Neuroprotection; Oxidative Stress; Piperidines; Receptors, Neurokinin-1; Spatial Memory; Substance P	2019
High-Frequency Activation of Nucleus Accumbens D1-MSNs Drives Excitatory Potentiation on D2-MSNs. Neuron, 2019, 08-07, Volume: 103, Issue:3 Topics: Action Potentials; Animals; Aprepitant; Calcium Signaling; Cholinergic Neurons; Dopaminergic Neurons; Excitatory Postsynaptic Potentials; Interneurons; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Motivation; Neurokinin-1 Receptor Antagonists; Nucleus Accumbens; Photic Stimulation; Piperidines; Receptor, Muscarinic M1; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Neurokinin-1; Substance P	2019
Role of the Neurokinin-1 Receptor in the Promotion of Corneal Epithelial Wound Healing by the Peptides FGLM-NH2 and SSSR in Neurotrophic Keratopathy. Investigative ophthalmology & visual science, 2020, 07-01, Volume: 61, Issue:8 Topics: Animals; Corneal Injuries; Epithelium, Corneal; Insulin-Like Growth Factor I; Mice; Neurokinin-1 Receptor Antagonists; Neurotransmitter Agents; Piperidines; Proto-Oncogene Proteins c-akt; Receptors, Neurokinin-1; Signal Transduction; Substance P; Wound Healing	2020
Blocking NK1 receptors disrupts the sequential and temporal organization of chain grooming in rats. Neuropharmacology, 2021, 09-15, Volume: 196 Topics: Animals; Basal Ganglia; Behavior, Animal; Grooming; Markov Chains; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Receptors, Neurokinin-1; Substance P	2021
The NK1 antagonist L-733,060 facilitates sequence learning. Journal of psychopharmacology (Oxford, England), 2023, Volume: 37, Issue:6 Topics: Animals; Conditioning, Operant; Learning; Piperidines; Rats; Receptors, Neurokinin-1; Reinforcement, Psychology; Reward; Substance P	2023