substance p has been researched along with icatibant in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (68.18) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ichinose, M; Igarashi, A; Inoue, H; Miura, M; Nakajima, N; Shirato, K; Takahashi, T; Takishima, T; Yamauchi, H | 1 |
| Bertrand, C; Chan, B; Geppetti, P; Nadel, JA; Ricciardolo, FL; Yamawaki, I | 1 |
| Giuliani, S; Lecci, A; Maggi, CA; Meini, S | 1 |
| Damas, J | 1 |
| Cioncolini, F; Figini, M; Geppetti, P; Javdan, P | 1 |
| Brain, SD; Cambridge, H | 1 |
| Giuliani, S; Lecci, A; Lippe, IT; Maggi, CA; Santicioli, P | 1 |
| Bertrand, C; Geppetti, P; Nadel, JA; Yamawaki, I | 1 |
| Seybold, VS; Stucky, CL; Thayer, SA | 1 |
| Böhm, SK; Bunnett, NW; Caughey, GH; Corvera, CU; Déry, O; Khitin, LM; McConalogue, K; Payan, DG | 1 |
| Andersson, RG; Lindström, EG | 1 |
| Bunnett, NW; Emanueli, C; Figini, M; Geppetti, P; Grady, EF; Madeddu, P; Parisi, D; Regoli, D | 1 |
| Brain, SD; Towler, PK | 1 |
| Baluk, P; Bunnett, NW; McDonald, DM; Murphy, TJ; Thurston, G | 1 |
| Ferreira, SH; Tonussi, CR | 1 |
| Cicha, MZ; Farley, DM; Kopp, UC; Smith, LA | 1 |
| Al-Rashed, S; Brain, SD; Cao, T; Gerard, N; Hoult, JR; Pintér, E | 1 |
| Carpenter, TC; Stenmark, KR | 1 |
| Fox, KA; Helmy, A; Newby, DE; Webb, DJ; Witherow, FN | 1 |
| Bergren, DR | 1 |
| Antunes, E; Camargo, EA; de Nucci, G; Ferreira, T; Landucci, EC; Ribela, MT | 1 |
| Ali, H; Alkanfari, I; Gupta, K; Jahan, T | 1 |
1 trial(s) available for substance p and icatibant
| Article | Year |
|---|---|
Bradykinin contributes to the vasodilator effects of chronic angiotensin-converting enzyme inhibition in patients with heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Female; Forearm; Heart Failure; Heart Rate; Humans; Infusions, Intravenous; Male; Middle Aged; Plethysmography; Reference Values; Regional Blood Flow; Substance P; Vasodilation | 2001 |
21 other study(ies) available for substance p and icatibant
| Article | Year |
|---|---|
Bradykinin-induced airway inflammation. Contribution of sensory neuropeptides differs according to airway site.
Topics: Animals; Asthma; Atropine; Bradykinin; Capillary Permeability; Dipeptides; Evans Blue; Guinea Pigs; Indoles; Indomethacin; Inflammation; Male; Neurons, Afferent; Premedication; Propranolol; Substance P; Tachykinins | 1994 |
Tachykinins and kinins in antigen-evoked plasma extravasation in guinea-pig nasal mucosa.
Topics: Animals; Biphenyl Compounds; Bradykinin; Capillary Permeability; Capsaicin; Evans Blue; Glycopeptides; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Kinins; Male; Nasal Mucosa; Nerve Endings; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Ovalbumin; Protease Inhibitors; Substance P; Tachykinins | 1994 |
Pharmacological analysis of the local and reflex responses to bradykinin on rat urinary bladder motility in vivo.
Topics: Adrenergic beta-Antagonists; Animals; Bradykinin; Capsaicin; Dose-Response Relationship, Drug; Indoles; Indomethacin; Injections, Spinal; Isoindoles; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Quinuclidines; Rats; Rats, Wistar; Reflex; Substance P; Urinary Bladder | 1995 |
Involvement of the kallikrein-kinin system in the salivary secretion elicited in rats by heat stress.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arginine; Atropine; Bradykinin; Hot Temperature; Kallikrein-Kinin System; Kallikreins; Kininogens; Male; Nitroarginine; Pilocarpine; Rats; Rats, Inbred BN; Rats, Wistar; Saliva; Stress, Physiological; Submandibular Gland; Substance P | 1994 |
Involvement of tachykinins in plasma extravasation induced by bradykinin and low pH medium in the guinea-pig conjunctiva.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Capsaicin; Conjunctiva; Guinea Pigs; Hydrogen-Ion Concentration; Male; Neuritis; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Bradykinin; Substance P; Tachykinins | 1995 |
Mechanism of bradykinin-induced plasma extravasation in the rat knee joint.
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Blood Pressure; Bradykinin; Capillary Permeability; Enzyme Inhibitors; Indoles; Injections, Intra-Articular; Isoindoles; Knee Joint; Male; Mast Cells; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidopamine; Perfusion; Rats; Rats, Wistar; Regional Blood Flow; Serum Albumin; Substance P; Sympathectomy; Synovial Fluid | 1995 |
Effect of bradykinin and tachykinin receptor antagonist on xylene-induced cystitis in rats.
Topics: Administration, Intravesical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Cystitis; Female; Rats; Rats, Wistar; Substance P; Xylenes | 1993 |
Role of kinins in the vascular extravasation evoked by antigen and mediated by tachykinins in guinea pig trachea.
Topics: Animals; Antigens; Biphenyl Compounds; Bradykinin; Capillary Permeability; Guinea Pigs; Kinins; Male; Neurons, Afferent; Ovalbumin; Substance P; Tachykinins; Trachea | 1993 |
Prostaglandin E2 increases the proportion of neonatal rat dorsal root ganglion neurons that respond to bradykinin.
Topics: Animals; Animals, Newborn; Bradykinin; Bradykinin Receptor Antagonists; Calcium; Cell Size; Cells, Cultured; Dinoprostone; Epoprostenol; Ganglia, Spinal; Immunohistochemistry; Neurons; Rats; Rats, Sprague-Dawley; Substance P | 1996 |
Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2.
Topics: Adrenergic beta-Antagonists; Animals; Benzimidazoles; Bradykinin; Calcium; Cells, Cultured; Chymases; Colon; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Gastrointestinal Motility; In Vitro Techniques; Indomethacin; Inflammation Mediators; Leupeptins; Mast Cells; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitroprusside; Rats; Receptor, PAR-2; Receptors, Cell Surface; Serine Endopeptidases; Substance P; Tetrodotoxin; Time Factors; Trypsin; Tryptases | 1997 |
Neurokinin A-LI release after antigen challenge in guinea-pig bronchial tubes: influence of histamine and bradykinin.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Bronchi; Capsaicin; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Ovalbumin; Pyrilamine; Substance P; Trachea | 1997 |
Acute ACE inhibition causes plasma extravasation in mice that is mediated by bradykinin and substance P.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Coloring Agents; Data Interpretation, Statistical; Enalapril; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Indicators and Reagents; Indoles; Injections, Intravenous; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Organometallic Compounds; Piperidines; Quinuclidines; Substance P; Time Factors | 1998 |
Activity of tachykinin NK1 and bradykinin B2 receptor antagonists, and an opioid ligand at different stimulation parameters in neurogenic inflammation in the rat.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Edema; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Extravasation of Diagnostic and Therapeutic Materials; Male; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Peptide Fragments; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptor, Bradykinin B2; Receptors, Neurokinin-1; Receptors, Opioid, mu; Substance P; Time Factors | 1998 |
Neurogenic plasma leakage in mouse airways.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzamides; Blood Vessels; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Capsaicin; Captopril; Dose-Response Relationship, Drug; Evans Blue; Glycopeptides; Lung; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Piperidines; Protease Inhibitors; Quinuclidines; Receptors, Neurokinin-2; Skin; Specific Pathogen-Free Organisms; Substance P; Trachea; Urinary Bladder | 1999 |
Tumour necrosis factor-alpha mediates carrageenin-induced knee-joint incapacitation and also triggers overt nociception in previously inflamed rat knee-joints.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Bradykinin; Bradykinin Receptor Antagonists; Carrageenan; Dinoprostone; Inflammation Mediators; Injections, Intra-Articular; Knee Joint; Male; Pain; Rats; Rats, Wistar; Stimulation, Chemical; Substance P; Tumor Necrosis Factor-alpha | 1999 |
Activation of renal mechanosensitive neurons involves bradykinin, protein kinase C, PGE(2), and substance P.
Topics: Adrenergic beta-Antagonists; Analgesics; Animals; Antimetabolites; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Indoles; Isoindoles; Kidney; Kidney Pelvis; Male; Mechanoreceptors; Naphthalenes; Natriuresis; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Pressure; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Receptors, Bradykinin; Receptors, Neurokinin-1; Substance P | 2000 |
Neurokinin-1 receptor agonists are involved in mediating neutrophil accumulation in the inflamed, but not normal, cutaneous microvasculature: an in vivo study using neurokinin-1 receptor knockout mice.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Carrageenan; Cell Movement; Drug Combinations; Female; Injections, Intradermal; Injections, Intravenous; Interleukin-1; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Neutrophils; Receptors, Neurokinin-1; Skin; Substance P; Zymosan | 2000 |
Hypoxia decreases lung neprilysin expression and increases pulmonary vascular leak.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Gene Expression Regulation, Enzymologic; Hypoxia; Lung; Male; Methionine; Microcirculation; Neprilysin; Neurokinin-1 Receptor Antagonists; Oxygen; Piperidines; Protease Inhibitors; Pulmonary Edema; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Specific Pathogen-Free Organisms; Substance P; Water | 2001 |
Prostaglandin involvement in lung C-fiber activation by substance P in guinea pigs.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Asthma; Blood Pressure; Bradykinin; Capsaicin; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Guinea Pigs; Heart Rate; Indomethacin; Lung; Nerve Fibers, Unmyelinated; Prostaglandins; Respiratory Hypersensitivity; Substance P | 2006 |
Role of substance P and bradykinin in acute pancreatitis induced by secretory phospholipase A2.
Topics: Acute Disease; Amylases; Animals; Bradykinin; Bradykinin B2 Receptor Antagonists; Disease Models, Animal; Lung; Male; Neurokinin-1 Receptor Antagonists; Pancreas; Pancreatitis; Peroxidase; Phospholipases A2, Secretory; Piperidines; Pneumonia; Quinuclidines; Rats; Rats, Wistar; Receptor, Bradykinin B2; Receptors, Neurokinin-1; Substance P; Tumor Necrosis Factor-alpha | 2008 |
Naturally Occurring Missense MRGPRX2 Variants Display Loss of Function Phenotype for Mast Cell Degranulation in Response to Substance P, Hemokinin-1, Human β-Defensin-3, and Icatibant.
Topics: Animals; beta-Defensins; Bradykinin; Cell Degranulation; Cell Line, Tumor; Humans; Ligands; Loss of Function Mutation; Mast Cells; Mutation, Missense; Nerve Tissue Proteins; Neuropeptides; Phenotype; Rats; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Substance P; Tachykinins | 2018 |