Page last updated: 2024-08-23

substance p and guaifenesin

substance p has been researched along with guaifenesin in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (29.27)	18.7374
1990's	21 (51.22)	18.2507
2000's	5 (12.20)	29.6817
2010's	3 (7.32)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Sjöberg, E; Skoglund, CR	1
Bleicher, S; Freyer-Barski, A; Hahn, HL; Hümmer, B	1
Ishide, N; Ishihara, H; Masuda, T; Miura, M; Sasaki, H; Sasaki, T; Sato, M; Shimura, S; Takishima, T	1
Ishihara, H; Masuda, T; Sasaki, H; Sasaki, T; Satoh, M; Shimura, S; Takishima, T	1
Lim, JC; Webber, SE; Widdicombe, JG	1
Barnes, PJ; Kuo, HP; Rogers, DF; Rohde, JA; Tokuyama, K	1
Aiello, E; Hernandez, C; Kennedy, J	1
Uchihashi, K; Ueba, H	1
Dolata, J; Lindberg, S; Mercke, U	1
Borson, DB; Caughey, G; Corrales, R; Gold, M; Nadel, JA; Ramachandran, J; Varsano, S; Viro, N	1
Gamse, R; Saria, A; Wolf, G	1
Schaffalitzky de Muckadell, OB; Tønnesen, P	1
Okayama, H; Sasaki, H; Sasaki, T; Shimura, S; Takishima, T	1
Mygind, N; Schaffalitzky de Muckadell, OB; Tønnesen, P	1
Richardson, PS; Webber, SE	1
Shimura, S	1
Webber, SE	1
Aursudkij, B; Barnes, PJ; Rogers, DF	1
Bhaskar, KR; Coles, SJ; Neill, KH; O'Sullivan, DD; Reid, LM	1
Ishihara, A; Jeon, SY; Kawaguchi, S; Majima, Y; Nakano, K; Sakakura, Y; Yasui, Y	1
Cho, CH; Ko, JK; Tang, XL	1
Barth, PJ; Bredenbröker, D; Fehmann, HC; von Wichert, P; Wagner, U; Yu, F	1
Châtelain, C; Lacroix, JS; Pochon, N	1
De Sanctis, GT; King, M; Ramirez, O; Rubin, BK	1
Mak, JC; Meini, S; Rogers, DF; Rohde, JA	1
Blanchard, JC; Carruette, A; Garret, C; Laduron, PM; Montier, F; Moussaoui, SM	1
Chang, CK; Tomic, S; Warner, TF	1
Caramori, G; Ciaccia, A; Fabbri, L; Facchini, F; Lucchini, RE; Maestrelli, P; Mapp, CE; Polak, JM; Saetta, M; Springall, DR; Turato, G	1
Iwabuchi, Y; Iwasaki, S; Okumura, Y	1
Chen, HH; Kuo, HP	1
Ali, M; Baraniuk, JN; Fang, SY; Naranch, K; Yuta, A	1
Khawaja, AM; Liu, YC; Rogers, DF	1
Khawaja, AM; Liu, Y; Rogers, DF	1
Chu, HW; Kraft, M; Krause, JE; Martin, RJ; Rex, MD	1
Khan, S; Khawaja, AM; Liu, YC; Manzini, S; Rogers, DF	1
Fehér, J; Koszegi, T; Kovács, B; Kovács, I; Ludány, A; Pintér, E; Szolcsányi, J	1
Choi, JY; Hanrahan, JW; Ianowski, JP; Wine, JJ	1
Choi, JY; Joo, NS; Khansaheb, M; Krouse, ME; Robbins, RC; Weill, D; Wine, JJ	1
Choi, HS; Choi, JY; Kim, SC; Lee, HJ; Lee, WI; Yang, WS	1
Choi, JY; Joo, NS; Khansaheb, M; Krouse, M; Wine, JJ; Yang, YM	1
Abdullah, AH; Ismail, NFF; Lim, SM; Mastuki, MF; Ming, LC; Neoh, CF; Ramasamy, K; Saim, L; Zainuddin, N	1

Reviews

2 review(s) available for substance p and guaifenesin

Article	Year
The control of mucous secretion in the airways by peptidergic mechanisms. The American review of respiratory disease, 1987, Volume: 136, Issue:6 Pt 2 Topics: Animals; Methacholine Chloride; Methacholine Compounds; Mucous Membrane; Mucus; Muramidase; Neuropeptides; Phenylephrine; Substance P; Trachea; Vasoactive Intestinal Peptide	1987
Airway mucus: composition and regulation of its secretion by neuropeptides in vitro. Ciba Foundation symposium, 1984, Volume: 109 Topics: Animals; Dogs; Exocrine Glands; Glycoproteins; Humans; In Vitro Techniques; Mucus; Nerve Tissue Proteins; Respiratory System; Substance P; Vasoactive Intestinal Peptide	1984

Trials

4 trial(s) available for substance p and guaifenesin

Article	Year
Substance P and vasoactive intestinal peptide in serotonin-induced nasal secretions in normal subjects. Allergy, 1987, Volume: 42, Issue:2 Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Middle Aged; Mucus; Nasal Mucosa; Nasal Provocation Tests; Serotonin; Substance P; Vasoactive Intestinal Peptide	1987
Functional effects of phosphoramidon and captopril on exogenous neuropeptides in human nasal mucosa. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1995, Volume: 252, Issue:2 Topics: Adult; Airway Resistance; Blood Flow Velocity; Calcitonin Gene-Related Peptide; Captopril; Drug Synergism; Endothelium, Vascular; Glycopeptides; Humans; Laser-Doppler Flowmetry; Middle Aged; Mucus; Nasal Mucosa; Neprilysin; Peptidyl-Dipeptidase A; Protease Inhibitors; Substance P; Time Factors; Vasoactive Intestinal Peptide	1995
Substance P and its receptor neurokinin 1 expression in asthmatic airways. The Journal of allergy and clinical immunology, 2000, Volume: 106, Issue:4 Topics: Adult; Anti-Bacterial Agents; Asthma; Biopsy; Bronchi; Epithelium; Female; Forced Expiratory Volume; Humans; Male; Mucus; Mycoplasma pneumoniae; Receptors, Neurokinin-1; Substance P	2000
The immediate effect of facial candling on inflammatory mediators, substance P, symptoms severity, and quality of life in allergic rhinitis patients: Study protocol for a randomized controlled trial. Medicine, 2017, Volume: 96, Issue:30 Topics: Academic Medical Centers; Adolescent; Adult; Aged; Biomarkers; Humans; Malaysia; Medicine, East Asian Traditional; Middle Aged; Mucus; Nasal Cavity; Quality of Life; Rhinitis, Allergic; Severity of Illness Index; Substance P; Time Factors; Treatment Outcome; Young Adult	2017

Other Studies

35 other study(ies) available for substance p and guaifenesin

Article	Year
In vivo studies of individual mucous glands in the frog. Acta physiologica Scandinavica, 1977, Volume: 100, Issue:4 Topics: Animals; Anura; Electric Stimulation; Epithelial Cells; Epithelium; Exocrine Glands; Mucus; Muscle Contraction; Muscle, Smooth; Rana esculenta; Rana temporaria; Substance P; Sympathetic Nervous System; Xenopus	1977
[Stimulation of mucous glands of the respiratory tract by neuropeptides: comparison of exogenous administration and endogenous liberation]. Pneumologie (Stuttgart, Germany), 1990, Volume: 44 Suppl 1 Topics: Animals; Exocrine Glands; Female; Ferrets; Male; Mucus; Neurokinin A; Neurokinin B; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Trachea	1990
Intracellular calcium concentration of acinar cells in feline tracheal submucosal glands. The American journal of physiology, 1990, Volume: 259, Issue:6 Pt 1 Topics: Animals; Calcium; Cats; Detergents; Exocrine Glands; Glycerol; Glycoproteins; In Vitro Techniques; Kinetics; Methacholine Chloride; Mucus; Muscle, Smooth; Phenylephrine; Substance P; Trachea; Vasoactive Intestinal Peptide	1990
[Airway hyperresponsiveness and mucus secretion]. Nihon Kyobu Shikkan Gakkai zasshi, 1990, Volume: 28, Issue:10 Topics: Asthma; Autonomic Nervous System; Bronchi; Exocrine Glands; Humans; Mucus; Platelet Activating Factor; Substance P	1990
The effects of calcitonin gene-related peptide on submucosal gland secretion and epithelial albumin transport in the ferret trachea in vitro. British journal of pharmacology, 1991, Volume: 102, Issue:1 Topics: Albumins; Animals; Calcitonin Gene-Related Peptide; Evoked Potentials; Exocrine Glands; Female; Ferrets; In Vitro Techniques; Male; Methacholine Compounds; Mucus; Muramidase; Substance P; Thiorphan; Trachea	1991
Capsaicin and sensory neuropeptide stimulation of goblet cell secretion in guinea-pig trachea. The Journal of physiology, 1990, Volume: 431 Topics: Anesthesia, General; Animals; Axons; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Exocrine Glands; Guinea Pigs; Male; Mucus; Neurokinin A; Neurokinin B; Neuropeptides; Substance P; Time Factors; Trachea	1990
Stimulation of frog ciliated cells in culture by acetylcholine and substance P. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1991, Volume: 99, Issue:3 Topics: Acetylcholine; Animals; Capsaicin; Cells, Cultured; Cilia; Epithelium; Microscopy; Mouth Mucosa; Mucociliary Clearance; Mucus; Palate; Rana pipiens; Stimulation, Chemical; Substance P; Video Recording	1991
Degranulation of acinar cells in von Ebner's gland of the rat. Journal of Osaka Dental University, 1991, Volume: 25, Issue:1 Topics: Animals; Autonomic Agents; Cytoplasmic Granules; Exocrine Glands; Male; Mucus; Rats; Rats, Inbred Strains; Substance P; Tongue	1991
Effects of neurokinin A and calcitonin gene-related peptide on mucociliary activity in rabbit maxillary sinus. Regulatory peptides, 1986, Dec-01, Volume: 16, Issue:1 Topics: Animals; Calcitonin Gene-Related Peptide; Cilia; Female; Male; Maxillary Sinus; Mucus; Neurokinin A; Neuropeptides; Rabbits; Substance P	1986
Enkephalinase inhibitors potentiate substance P-induced secretion of 35SO4-macromolecules from ferret trachea. Experimental lung research, 1987, Volume: 12, Issue:1 Topics: Animals; Drug Synergism; Endopeptidases; Enkephalin, Methionine; Ferrets; Glycopeptides; In Vitro Techniques; Male; Molecular Weight; Mucus; Neprilysin; Protease Inhibitors; Rabbits; Substance P; Sulfates; Thiorphan; Tiopronin; Trachea	1987
[New aspects of the autonomic innervation of human nasal mucosa]. Laryngologie, Rhinologie, Otologie, 1987, Volume: 66, Issue:3 Topics: Acetylcholine; Afferent Pathways; Autonomic Nervous System; Humans; Mucus; Muscle, Smooth, Vascular; Nasal Mucosa; Norepinephrine; Substance P; Vasodilation	1987
Effect of substance P on mucus secretion of isolated submucosal gland from feline trachea. Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:2 Topics: Animals; Cats; Exocrine Glands; Glycoconjugates; In Vitro Techniques; Mucus; Substance P; Trachea	1987
Nasal challenge with serotonin in asymptomatic hay fever patients. Allergy, 1987, Volume: 42, Issue:6 Topics: Adult; Airway Resistance; Female; Humans; Male; Mucus; Nasal Mucosa; Nasal Provocation Tests; Pruritus; Rhinitis, Allergic, Seasonal; Serotonin; Sneezing; Substance P	1987
[Airway mucus secretion and neuropeptides]. Kokyu to junkan. Respiration & circulation, 1989, Volume: 37, Issue:5 Topics: Animals; Bronchi; Cats; Exocrine Glands; In Vitro Techniques; Mucus; Substance P; Vasoactive Intestinal Peptide	1989
Receptors mediating the effects of substance P and neurokinin A on mucus secretion and smooth muscle tone of the ferret trachea: potentiation by an enkephalinase inhibitor. British journal of pharmacology, 1989, Volume: 98, Issue:4 Topics: Animals; Female; Ferrets; In Vitro Techniques; Male; Mucus; Muramidase; Muscle Tonus; Muscle, Smooth; Neprilysin; Neurokinin A; Receptors, Cell Surface; Serum Albumin, Bovine; Substance P; Thiorphan; Trachea	1989
Effects of tachykinins on mucus secretion in human bronchi in vitro. European journal of pharmacology, 1989, Dec-19, Volume: 174, Issue:2-3 Topics: Adolescent; Adult; Aged; Bronchi; Child; Female; Glycopeptides; Humans; In Vitro Techniques; Male; Middle Aged; Mucus; Neprilysin; Neurokinin A; Neurokinin B; Substance P; Tachykinins	1989
Immunohistochemical and electron microscopic studies of substance P in guinea pig nasal glands. Acta oto-laryngologica. Supplementum, 1993, Volume: 506 Topics: Animals; Exocrine Glands; Female; Guinea Pigs; Immunohistochemistry; Microscopy, Electron; Mucus; Nasal Mucosa; Nerve Endings; Substance P	1993
The differential mechanisms of mild irritants on adaptive cytoprotection. Journal of gastroenterology and hepatology, 1994, Volume: 9 Suppl 1 Topics: Adaptation, Physiological; Animals; Arginine; Atropine; Capsaicin; Chorionic Gonadotropin; Ethanol; Gastric Mucosa; Hexamethonium; Indomethacin; Irritants; Lidocaine; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Stomach Ulcer; Substance P	1994
Galanin and somatostatin inhibition of substance P-induced airway mucus secretion in the rat. Neuropeptides, 1995, Volume: 28, Issue:1 Topics: Animals; Dose-Response Relationship, Drug; Galanin; Lung; Male; Mucus; Peptides; Rats; Rats, Sprague-Dawley; Somatostatin; Substance P; Trachea	1995
Ferret tracheal mucus rheology, clearability and volume following administration of substance P or methacholine. The European respiratory journal, 1993, Volume: 6, Issue:1 Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Elasticity; Ferrets; Male; Methacholine Chloride; Mucociliary Clearance; Mucus; Rheology; Substance P; Trachea; Viscosity	1993
Tachykinin control of ferret airways: mucus secretion, bronchoconstriction and receptor mapping. Neuropeptides, 1993, Volume: 24, Issue:2 Topics: Animals; Bronchoconstriction; Capsaicin; Ferrets; Male; Methacholine Chloride; Mucus; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Reproducibility of Results; Stimulation, Chemical; Substance P; Tachykinins; Trachea	1993
A non-peptide NK1-receptor antagonist, RP 67580, inhibits neurogenic inflammation postsynaptically. British journal of pharmacology, 1993, Volume: 109, Issue:1 Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Capsaicin; Electric Stimulation; Indoles; Inflammation; Injections, Intravenous; Isoindoles; Male; Morphine; Mucus; Nasal Mucosa; Pyrroles; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Synapses; Thiophenes; Xylenes	1993
Neuroendocrine cell-axonal complexes in the minor vestibular gland. The Journal of reproductive medicine, 1996, Volume: 41, Issue:6 Topics: Adult; Axons; Epithelium; Exocrine Glands; Female; Humans; Immunohistochemistry; Mucus; Neurosecretory Systems; Phosphopyruvate Hydratase; Serotonin; Substance P; Vaginal Diseases; Vulvar Diseases	1996
Increased VIP-positive nerve fibers in the mucous glands of subjects with chronic bronchitis. American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Bronchi; Bronchitis; Calcitonin Gene-Related Peptide; Chronic Disease; Exocrine Glands; Humans; Immunohistochemistry; Male; Middle Aged; Mucus; Nerve Tissue Proteins; Neurons; Smoking; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase; Vasoactive Intestinal Peptide	1997
Histological and ultrastructural studies of the effects of tachykinins on protein secretion from the lingual epithelium and the lingual gland of the Tokyo daruma pond frog (Rana porosa porosa). Archives of oral biology, 1998, Volume: 43, Issue:6 Topics: Animals; Cytoplasmic Granules; Eledoisin; Epithelial Cells; Female; Male; Mouth Mucosa; Mucus; Neurokinin A; Physalaemin; Ranidae; Saliva; Salivary Glands; Salivary Proteins and Peptides; Salivation; Substance P; Tachykinins; Tongue	1998
Effect of sensory neuropeptides on mucus secretion from cultured goblet cells. Changgeng yi xue za zhi, 1998, Volume: 21, Issue:3 Topics: Animals; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Exocytosis; Guinea Pigs; Male; Mucus; Neurokinin A; Neurokinin B; Substance P; Trachea	1998
Hypertonic saline nasal provocation stimulates nociceptive nerves, substance P release, and glandular mucous exocytosis in normal humans. American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:2 Topics: Administration, Intranasal; Adult; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Exocytosis; Female; Humans; Male; Mucus; Nasal Mucosa; Nociceptors; Receptors, Neurokinin-1; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Saline Solution, Hypertonic; Substance P	1999
Effect of fenspiride, a non-steroidal antiinflammatory agent, on neurogenic mucus secretion in ferret trachea in vitro. Pulmonary pharmacology & therapeutics, 1999, Volume: 12, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Electric Stimulation; Ferrets; Histamine Antagonists; Male; Mucus; Neurokinin A; Parasympathetic Nervous System; Receptors, Neurokinin-1; Spiro Compounds; Substance P; Sulfates; Sulfur Radioisotopes; Trachea	1999
Effect of non-peptide tachykinin NK(1) receptor antagonists on non-adrenergic, non-cholinergic neurogenic mucus secretion in ferret trachea. European journal of pharmacology, 1999, Nov-19, Volume: 384, Issue:2-3 Topics: Acetylcholine; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Ferrets; In Vitro Techniques; Iodine Radioisotopes; Male; Membranes; Mucus; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Piperidines; Quinolines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Trachea	1999
Effect of the long-acting tachykinin NK(1) receptor antagonist MEN 11467 on tracheal mucus secretion in allergic ferrets. British journal of pharmacology, 2001, Volume: 132, Issue:1 Topics: Acetylcholine; Animals; Autonomic Nervous System; Cyclohexylamines; Electric Stimulation; Ferrets; Histamine; Hypersensitivity; Indoles; Male; Mucus; Neurokinin-1 Receptor Antagonists; Ovalbumin; Receptors, Neurokinin-1; Substance P; Sulfur Radioisotopes; Trachea	2001
Substance P released from sensory nerve endings influences tear secretion and goblet cell function in the rat. Neuropeptides, 2005, Volume: 39, Issue:4 Topics: Animals; Cell Count; Electric Stimulation; Eye Proteins; Goblet Cells; Lacrimal Apparatus; Male; Mucus; Nerve Endings; Neurons, Afferent; Rats; Rats, Wistar; Substance P; Tears; Trigeminal Ganglion	2005
Substance P stimulates CFTR-dependent fluid secretion by mouse tracheal submucosal glands. Pflugers Archiv : European journal of physiology, 2008, Volume: 457, Issue:2 Topics: Animals; Benzoates; Capsaicin; Clotrimazole; Cystic Fibrosis Transmembrane Conductance Regulator; Exocrine Glands; Irritants; Mice; Mice, Inbred CFTR; Mucus; Neurokinin-1 Receptor Antagonists; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Receptors, Neurokinin-1; Respiratory Mucosa; Substance P; Thiazolidines; Time Factors; Trachea; Tryptophan	2008
Substance P stimulates human airway submucosal gland secretion mainly via a CFTR-dependent process. The Journal of clinical investigation, 2009, Volume: 119, Issue:5 Topics: Age Factors; Animals; Calcium Signaling; Capsicum; Carbachol; Chelating Agents; Clotrimazole; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Exocrine Glands; Female; Humans; In Vitro Techniques; Male; Mucus; Plant Oils; Substance P; Sus scrofa; Trachea; Vasoactive Intestinal Peptide	2009
Functional study of mucus secretion of the eustachian tube in Guinea pigs. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2010, Volume: 31, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Calcium; Carbachol; Colforsin; Computer Systems; Cyclic AMP; Eustachian Tube; Exocrine Glands; Guinea Pigs; In Vitro Techniques; Isoproterenol; Kinetics; Male; Mucus; Nicotinic Agonists; Phenylephrine; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Substance P	2010
Properties of substance P-stimulated mucus secretion from porcine tracheal submucosal glands. American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 300, Issue:3 Topics: Animals; Anions; Calcium; Capsaicin; Carbachol; Cystic Fibrosis Transmembrane Conductance Regulator; Fura-2; Humans; In Vitro Techniques; Microscopy, Interference; Mucus; Respiratory Mucosa; Substance P; Sus scrofa; Time Factors; Trachea; Type C Phospholipases	2011