Page last updated: 2024-08-23

substance p and formaldehyde

substance p has been researched along with formaldehyde in 99 studies

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-199013 (13.13)18.7374
1990's41 (41.41)18.2507
2000's26 (26.26)29.6817
2010's19 (19.19)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grimelius, L; Lundqvist, G; Portela-Gomes, G; Skoog, V; Westermark, P; Wilander, E1
Berge, OG; Hole, K; Lund, A; Mjellem-Joly, N1
Chayvialle, JA; Chéry-Croze, S; Miampamba, M1
Inoki, R; Ohkubo, T; Shibata, M; Takahashi, H2
Goldstein, BD; McCarson, KE3
Goldstein, BD; Holland, LN2
Cowan, A; Larson, AA; Murray, CW1
Ono, M; Satoh, T1
Anderson, K; Bernstein, D; Cominelli, F; Davis, W; Eysselein, VE; Khan, H; Nast, CC; Patel, A; Reinshagen, M; Sternini, C1
Ferrell, WR; Lam, FY1
Goldstein, BD; Kantner, RM; Kirby, ML2
Wakisaka, S1
Fasmer, OB; Hole, K; Post, C1
Besson, JM; Calvino, B; Couraud, JY; Maillet, S; Pradelles, P1
Hanashima, N; Hirota, N; Kuraishi, Y; Sato, Y; Satoh, M; Takagi, H1
Fujita, T; Iwanaga, T; Teraki, Y; Yoshie, S1
Fasmer, OB; Hole, K; Hunskaar, S1
Somogyi, P; Takagi, H1
Mishima, H; Sears, M; Stjernschantz, J1
McDonald, DM1
Bravo, R; Herdegen, T; Mayer, B; Rüdiger, S; Zimmermann, M1
Mi, ZP; Qiao, JT; Zhang, RX1
Coderre, TJ; Yashpal, K1
Krause, JE; McCarson, KE1
Hayashi, K; Kuraishi, Y; Nagasawa, T; Satoh, M1
Katsumata, K; Kisara, K; Ohba, M; Sakurada, S; Sakurada, T; Tan-No, K; Yogo, H1
Coderre, TJ; Henry, JL; Radhakrishnan, V; Yashpal, K1
Mi, ZP; Qiao, JT; Xie, YF; Zhang, RX1
Hitosugi, H; Kamei, J; Kasuya, Y2
Katsumata, K; Kisara, K; Sakurada, S; Sakurada, T; Tan-No, K; Yogo, H1
Carruette, A; Garret, C; Moussaoui, S1
Katsumata, K; Kisara, K; Manome, Y; Ohba, M; Sakurada, S; Sakurada, T; Tan-No, K1
Ohkubo, T; Shibata, M; Takahashi, H1
Canella, R; Leon, A; Marcolongo, G; Mazzari, S; Petrelli, L1
Traub, RJ1
Boyce, S; Carlson, E; Hill, RG; Rupniak, NMJ; Webb, JK1
Goettl, VM; Larson, AA1
Boucher, S; Couture, R; Gehlert, DR; Helton, DR; Hipskind, PA; Iyengar, S; Kallman, MJ; Li, DL; Lobb, KL; Nixon, JA; Schober, D; Simmons, RM1
Chen, P; Hua, XY; Marsala, M; Nagy, I; Phillips, E; Polgar, E; Urban, L; Webb, M; Wollaston, L; Yaksh, TL1
Altier, N; Stewart, J1
Baffi, J; König, M; Mezey, E; Palkovits, M; Reynolds, K; Usdin, T; Zimmer, A; Zimmer, AM1
Belmonte, C; Cervero, F; De Felipe, C; Doyle, CA; Herrero, JF; Hunt, SP; Laird, JM; O'Brien, JA; Palmer, JA; Smith, AJ1
Choi, HS; Kim, SK; Nah, JJ; Nah, SY; Nam, KY; Shin, YH; Yoon, SR1
Calixto, JB; Campos, MM; Cechinel Filho, V; Mendes, GL; Santos, AR; Tratsk, KS; Yunes, RA1
Betsholtz, C; Gebre-Medhin, S; Mulder, H; Sundler, F; Zhang, Y1
Chabot, J; Coderre, TJ; Henry, JL; Pitcher, GM; Yashpal, K1
McCarson, KE1
Calcutt, NA; Gustafsson, H; Malmberg, AB; Stiller, C1
Choi, SS; Chung, KM; Lee, KC; Suh, HW1
Hashimoto, T; Iijima, Y; Ishigooka, M; Nakada, T; Yaguchi, H1
Forrest, L; Hughes, C; Puskar, Z; Spike, RC; Todd, AJ; Watt, C1
Salam, OM1
Calixto, JB; Cechinel-Filho, V; Ferreira, J; Malheiros, A; Santos, AR; Scheidt, C; Yunes, RA1
Dun, NJ; Hua, F; Ricketts, BA; Williams, CA1
Adler, G; Eysselein, VE; Reinshagen, M1
Inoue, M; Kawashima, T; Kishioka, S; Maeda, T; Matsumoto, M; Rashid, MH; Ueda, H1
Blisnick, T; Desor, D; Dugave, C; Hermitte, V; Messaoudi, M; Rigault, AG; Rougeon, F; Rougeot, C1
Anderson, LJ; Barskey, A; Haynes, LM; Jones, LP; Tripp, RA1
Calcutt, NA; Campana, WM; Catalano, R; Feng, Y; Freshwater, JD; Marsala, M; Protter, AA; Scott, B; Svensson, CI; Westerlund, A; Yaksh, TL1
Choi, SS; Han, EJ; Han, KJ; Lee, HK; Suh, HW1
Czaja, K; Kaleczyc, J; Lakomy, M; Pidsudko, Z; Sienkiewicz, W; Wasowicz, K1
Del Turco, D; Deller, T; Feil, R; Geisslinger, G; Hofmann, F; Ruth, P; Sausbier, M; Schmidtko, A; Tegeder, I1
de Francischi, JN; Lisboa, MC; Santos, JM; Tatsuo, MA; Turchetti-Maia, RM1
Bianchi, M; Biella, G; Ferrario, P; Martucci, C; Sacerdote, P1
Liu, Y; Yang, MH; Zhang, HY1
Kato, M; Kuramasu, A; Mobarakeh, JI; Orito, T; Sakurada, S; Sakurai, E; Yanai, K; Yoshida, A1
Fu, NA; Liu, JY; Wang, QX; Wang, XY; Yao, SL1
Akada, Y; Amano, K; Fukudome, Y; Itoh, M; Ogawa, S; Yamamoto, I; Yamasaki, F1
DeHate, RB; Richards, IS1
Buscone, S; Di Bella, P; Greco, R; Nappi, G; Sandrini, G; Tassorelli, C1
Choi, HW; Jang, JE; Jung, JS; Kwon, MS; Lee, JK; Park, SH; Seo, YJ; Suh, HW1
Choi, HW; Choi, SM; Jung, JS; Kwon, MS; Lee, JK; Nam, JS; Park, SH; Seo, YJ; Suh, HW1
Christianson, CA; Hua, XY; Nazarian, A; Yaksh, TL1
Dong, H; Geng, X; Lu, X; Yu, H; Zeng, Y; Zhang, L1
Ito, K; Miyake, M; Muto, T; Ohshima, M; Sakamoto, T; Takeda, M; Ueda, N1
Csillik, B; Knyihár-Csillik, E; Mihály, A1
Ballard, CJ; Hurley, JH; Kunkler, PE; Oxford, GS1
Fitzsimmons, B; Hua, XY; Newton, AC; O'Neill, A; Steinauer, J; Xu, Q; Yaksh, TL1
Beaudry, H; Dubois, D; Gendron, L1
Ikeda, T; Naono-Nakayama, R; Nishimori, T; Sunakawa, N1
Akasaka, Y; Hatta, A; Inoue, H; Sakai, A; Suzuki, H; Takasu, K; Tsukahara, M1
Ikeda, T; Matsushima, O; Naono-Nakayama, R; Nishimori, T; Sunakawa, N1
Jin, Y; Li, C; Liu, W; Wang, F1
Chen, PX; Guo, HM; Huang, JH; Luo, YL; Zhang, YL; Zhou, WL; Zhu, YX1
Hisaoka-Nakashima, K; Izumi, H; Morioka, N; Nakamura, Y; Nakata, Y; Shimizu, T1
Chen, T; Ji, W; Li, H; Li, YQ; Pei, LY; Wang, W; Wu, SX; Zhang, MM; Zhang, T1
Chen, R; Lai, K; Li, J; Li, L; Liu, X; Ma, P; Wu, Y; Yang, X; Yao, H; Ye, X; You, H; Yuan, Y1
Kang, YJ; Kim, CH; Kim, SJ; Kim, SS; Lim, SM; Park, SH; Sim, YB; Suh, HW1
Almasarweh, F; Are, D; Armendariz, A; Nazarian, A; Tenayuca, JM1
Ganev, EG; Hiruma-Lima, CA; Martins, DF; Mazzardo-Martins, L; Nishijima, CM; Rocha, LR; Santos, AR1
Ebihara, K; Funahashi, H; Ikeda, T; Ishida, Y; Koganemaru, G; Kuramashi, A; Naono-Nakayama, R; Nishimori, T1
Dong, YL; Li, YQ; Lu, YC; Wang, J; Wang, W; Wei, YY; Wu, HH; Wu, SX; Yin, JB; Zhang, T; Zhang, Y1
Hong, JW; Jang, SP; Lee, HJ; Lee, JR; Park, SH; Suh, HW1

Other Studies

99 other study(ies) available for substance p and formaldehyde

ArticleYear
Substance P and enteroglucagon-like immunoreactivity in argentaffin and argyrophil midgut carcinoid tumours.
    Scandinavian journal of gastroenterology. Supplement, 1979, Volume: 53

    Topics: Aged; Carcinoid Tumor; Female; Fluorescent Antibody Technique; Formaldehyde; Gastrointestinal Hormones; Glucagon-Like Peptides; Humans; Immunoenzyme Techniques; Intestinal Neoplasms; Male; Middle Aged; Serotonin; Substance P

1979
Intrathecal co-administration of substance P and NMDA augments nociceptive responses in the formalin test.
    Pain, 1992, Volume: 51, Issue:2

    Topics: Animals; Formaldehyde; Injections, Spinal; Male; Mice; N-Methylaspartate; Nociceptors; Pain; Pain Measurement; Substance P

1992
Spinal and intestinal levels of substance P, calcitonin gene-related peptide and vasoactive intestinal polypeptide following perendoscopic injection of formalin in rat colonic wall.
    Neuropeptides, 1992, Volume: 22, Issue:2

    Topics: Animals; Calcitonin Gene-Related Peptide; Colitis; Colon, Sigmoid; Colonoscopy; Female; Formaldehyde; Neuropeptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Vasoactive Intestinal Peptide

1992
Roles of substance P and somatostatin on transmission of nociceptive information induced by formalin in spinal cord.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:3

    Topics: Animals; Capsaicin; Cysteamine; Drug Interactions; Formaldehyde; Mice; Pain; Pain Measurement; Somatostatin; Spinal Cord; Substance P; Synaptic Transmission

1990
Time course of the alteration in dorsal horn substance P levels following formalin: blockade by naloxone.
    Pain, 1990, Volume: 41, Issue:1

    Topics: Animals; Female; Foot; Formaldehyde; Injections; Naloxone; Rats; Rats, Inbred Strains; Sodium Chloride; Spinal Cord; Substance P; Time Factors

1990
Changes of substance P-like immunoreactivity in the dorsal horn are associated with the 'phasic' behavioral response to a formalin stimulus.
    Brain research, 1990, Dec-24, Volume: 537, Issue:1-2

    Topics: Animals; Behavior, Animal; Epinephrine; Formaldehyde; Immunochemistry; Lidocaine; Male; Nociceptors; Rats; Rats, Inbred Strains; Spinal Cord; Stereotyped Behavior; Stimulation, Chemical; Substance P

1990
Neurokinin and NMDA antagonists (but not a kainic acid antagonist) are antinociceptive in the mouse formalin model.
    Pain, 1991, Volume: 44, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Dose-Response Relationship, Drug; Formaldehyde; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Naloxone; Nociceptors; Pain; Peptide Fragments; Reaction Time; Substance P; Urethane

1991
Pharmacological studies on lappaconitine: antinociception and inhibition of the spinal action of substance P and somatostatin.
    Japanese journal of pharmacology, 1991, Volume: 55, Issue:4

    Topics: Aconitine; Analgesics; Animals; Behavior, Animal; Brain; Cysteamine; Diclofenac; Formaldehyde; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Morphine; Neurons; Nociceptors; Somatostatin; Spinal Cord; Substance P

1991
Calcitonin gene-related peptide and substance P decrease in the rabbit colon during colitis. A time study.
    Gastroenterology, 1991, Volume: 101, Issue:5

    Topics: Animals; Antigen-Antibody Complex; Calcitonin Gene-Related Peptide; Colitis; Colon; Formaldehyde; Immunohistochemistry; Intestinal Mucosa; Male; Nerve Fibers; Neurons; Rabbits; Substance P; Time Factors

1991
Neurogenic component of different models of acute inflammation in the rat knee joint.
    Annals of the rheumatic diseases, 1991, Volume: 50, Issue:11

    Topics: Animals; Capsaicin; Carrageenan; Disease Models, Animal; Formaldehyde; Hindlimb; Inflammation; Joints; Male; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Substance P; Uric Acid

1991
Release of substance P into the superficial dorsal horn following nociceptive activation of the hindpaw of the rat.
    Brain research, 1991, Dec-24, Volume: 568, Issue:1-2

    Topics: Animals; Formaldehyde; Hindlimb; Kinetics; Pain; Rats; Spinal Cord; Substance P; Time Factors

1991
Increase in substance P in the dorsal horn during a chemogenic nociceptive stimulus.
    Brain research, 1985, Jul-08, Volume: 338, Issue:1

    Topics: Animals; Electrophysiology; Female; Formaldehyde; Ganglia, Spinal; Immunoenzyme Techniques; Nociceptors; Photometry; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Time Factors

1985
[Immunohistochemical study on substance P in rat molar pulp and periodontal tissues. 1. Effect of decalcifying agents on substance P-like immunoreactivity].
    [Osaka Daigaku shigaku zasshi] The journal of Osaka University Dental Society, 1986, Volume: 31, Issue:1

    Topics: Animals; Decalcification Technique; Edetic Acid; Formaldehyde; Formates; Male; Mice; Mice, Inbred Strains; Picrates; Polymers; Spinal Cord; Spine; Substance P

1986
Regulatory mechanisms for substance P in the dorsal horn during a nociceptive stimulus: axoplasmic transport vs electrical activity.
    Brain research, 1986, Oct-22, Volume: 385, Issue:2

    Topics: Animals; Axonal Transport; Colchicine; Electrophysiology; Female; Formaldehyde; Nociceptors; Pain; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Tetrodotoxin

1986
Changes in nociception after acute and chronic administration of zimelidine: different effects in the formalin test and the substance P behavioural assay.
    Neuropharmacology, 1987, Volume: 26, Issue:4

    Topics: Animals; Behavior, Animal; Formaldehyde; Male; Mice; Pain; Substance P; Zimeldine

1987
Increased reactivity to chemical but not to heat noxious stimuli in mice producing anti-idiotypic antibodies for substance P.
    Brain research, 1988, Sep-20, Volume: 460, Issue:2

    Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Formaldehyde; Hot Temperature; Immunoglobulin Idiotypes; Male; Mice; Mice, Inbred BALB C; Pain; Substance P

1988
Stimulus specificity of peripherally evoked substance P release from the rabbit dorsal horn in situ.
    Neuroscience, 1989, Volume: 30, Issue:1

    Topics: Animals; Formaldehyde; Hot Temperature; Male; Pain; Physical Stimulation; Rabbits; Spinal Cord; Substance P

1989
Naloxone blocks the formalin-induced increase of substance P in the dorsal horn.
    Pain, 1989, Volume: 38, Issue:3

    Topics: Animals; Female; Formaldehyde; Immunoenzyme Techniques; Morphine; Naloxone; Pain; Rats; Rats, Inbred Strains; Spinal Cord; Substance P

1989
Modified formalin test: characteristic biphasic pain response.
    Pain, 1989, Volume: 38, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bromelains; Capsaicin; Dexamethasone; Dose-Response Relationship, Drug; Formaldehyde; Indomethacin; Male; Mice; Morphine; Nerve Fibers; p-Methoxy-N-methylphenethylamine; Pain; Pain Measurement; Sciatic Nerve; Substance P; Time Factors

1989
Immunocytochemistry of neuron-specific proteins and neuropeptides in taste buds and associated nerves.
    Archives of histology and cytology, 1989, Volume: 52 Suppl

    Topics: Animals; Calbindin 1; Calbindins; Calcium-Binding Proteins; Cats; Female; Formaldehyde; Guinea Pigs; Immunohistochemistry; Intermediate Filament Proteins; Male; Mice; Microscopy, Fluorescence; Nerve Tissue Proteins; Neurons; Phosphopyruvate Hydratase; Rats; S100 Calcium Binding Protein G; Substance P; Taste Buds

1989
Antinociceptive effects of serotonergic reuptake inhibitors in mice.
    Neuropharmacology, 1989, Volume: 28, Issue:12

    Topics: Alanine; Analgesics; Animals; Citalopram; Clomipramine; Desipramine; Formaldehyde; Hot Temperature; Male; Mice; Neurotransmitter Uptake Inhibitors; Serotonin Antagonists; Substance P

1989
A note on the use of picric acid-paraformaldehyde-glutaraldehyde fixative for correlated light and electron microscopic immunocytochemistry.
    Neuroscience, 1982, Volume: 7, Issue:7

    Topics: Animals; Axons; Brain; Enkephalin, Leucine; Fixatives; Formaldehyde; Glutaral; Histological Techniques; Immunoenzyme Techniques; Male; Microscopy, Electron; Muridae; Neurons; Neurotransmitter Agents; Picrates; Polymers; Somatostatin; Substance P; Synapses

1982
Role of substance P in the antidromic vasodilation, neurogenic plasma extravasation and disruption of the blood-aqueous barrier in the rabbit eye.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 321, Issue:4

    Topics: Animals; Aqueous Humor; Blood Pressure; Capillary Permeability; Ciliary Body; Eye; Female; Formaldehyde; Male; Rabbits; Substance P; Vasodilation

1982
Endothelial gaps and permeability of venules in rat tracheas exposed to inflammatory stimuli.
    The American journal of physiology, 1994, Volume: 266, Issue:1 Pt 1

    Topics: Animals; Blood Vessels; Capillary Permeability; Electric Stimulation; Endothelium, Vascular; Formaldehyde; Microcirculation; Microscopy, Electron; Rats; Rats, Inbred F344; Staining and Labeling; Substance P; Trachea; Vagus Nerve; Vasculitis; Venules

1994
Expression of nitric oxide synthase and colocalisation with Jun, Fos and Krox transcription factors in spinal cord neurons following noxious stimulation of the rat hindpaw.
    Brain research. Molecular brain research, 1994, Volume: 22, Issue:1-4

    Topics: Amino Acid Oxidoreductases; Animals; Calcitonin Gene-Related Peptide; DNA-Binding Proteins; Early Growth Response Protein 1; Foot; Formaldehyde; Genes, Immediate-Early; Immediate-Early Proteins; Immunohistochemistry; Male; NADPH Dehydrogenase; Nitric Oxide Synthase; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Transcription Factors; Zinc Fingers

1994
Examination of tonic nociceptive behavior using a method of substance P-receptor desensitization in the dorsal horn.
    Pain, 1994, Volume: 56, Issue:3

    Topics: Animals; Formaldehyde; Injections, Spinal; Male; Morphine; Naloxone; Nociceptors; Pain Measurement; Rats; Rats, Wistar; Receptors, Neurokinin-1; Reflex; Spinal Cord; Stereotyped Behavior; Substance P; Uric Acid

1994
Changes of spinal substance P, calcitonin gene-related peptide, somatostatin, Met-enkephalin and neurotensin in rats in response to formalin-induced pain.
    Regulatory peptides, 1994, Apr-14, Volume: 51, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Enkephalin, Methionine; Female; Formaldehyde; Image Processing, Computer-Assisted; Male; Microscopy, Electron; Neuropeptides; Neurotensin; Pain; Rats; Rats, Sprague-Dawley; Somatostatin; Spinal Cord; Substance P

1994
Intracellular messengers contributing to persistent nociception and hyperalgesia induced by L-glutamate and substance P in the rat formalin pain model.
    The European journal of neuroscience, 1994, Aug-01, Volume: 6, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arginine; Dexamethasone; Formaldehyde; Glutamic Acid; Hyperalgesia; Injections, Spinal; Isoquinolines; Male; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Pain; Pain Measurement; Pain Threshold; Piperazines; Protein Kinase C; Rats; Reflex; Substance P

1994
The formalin-induced expression of tachykinin peptide and neurokinin receptor messenger RNAs in rat sensory ganglia and spinal cord is modulated by opiate preadministration.
    Neuroscience, 1995, Volume: 64, Issue:3

    Topics: Animals; Formaldehyde; Ganglia, Spinal; Gene Expression Regulation; Male; Morphine; Naltrexone; Neurokinin B; Pain; Premedication; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-3; RNA, Messenger; Spinal Cord; Substance P; Time Factors

1995
Scratching behavior induced by pruritogenic but not algesiogenic agents in mice.
    European journal of pharmacology, 1995, Mar-14, Volume: 275, Issue:3

    Topics: Animals; Behavior, Animal; Capsaicin; Formaldehyde; Histamine; Male; Mice; p-Methoxy-N-methylphenethylamine; Pain; Pruritus; Substance P

1995
The neurokinin-1 receptor antagonist, sendide, exhibits antinociceptive activity in the formalin test.
    Pain, 1995, Volume: 60, Issue:2

    Topics: Animals; Behavior, Animal; Formaldehyde; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Peptide Fragments; Pyrrolidonecarboxylic Acid; Substance P

1995
CP-96,345, but not its stereoisomer, CP-96,344, blocks the nociceptive responses to intrathecally administered substance P and to noxious thermal and chemical stimuli in the rat.
    Neuroscience, 1993, Volume: 52, Issue:4

    Topics: Animals; Biphenyl Compounds; Blood Pressure; Formaldehyde; Heart Rate; Hot Temperature; Injections, Spinal; Male; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Spinal Cord; Stereoisomerism; Substance P

1993
Morphological evidence for the activation of descending modulatory control by nociceptive afferent pathways: an immunocytochemical study.
    Brain research, 1993, Feb-12, Volume: 603, Issue:1

    Topics: Afferent Pathways; Animals; Enkephalin, Methionine; Female; Formaldehyde; Immunohistochemistry; Male; Neurons, Afferent; Neurotensin; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

1993
Formalin-induced nociceptive responses in diabetic mice.
    Neuroscience letters, 1993, Jan-12, Volume: 149, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Formaldehyde; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Nociceptors; Receptors, Opioid, delta; Substance P

1993
Antinociception induced by CP 96,345, a non-peptide NK-1 receptor antagonist, in the mouse formalin and capsaicin tests.
    Neuroscience letters, 1993, Mar-19, Volume: 151, Issue:2

    Topics: Analgesics; Animals; Biphenyl Compounds; Capsaicin; Dose-Response Relationship, Drug; Formaldehyde; Hypnotics and Sedatives; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Naloxone; Pain; Pain Measurement; Postural Balance; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P

1993
Effects of mexiletine on formalin-induced nociceptive responses in mice.
    Research communications in chemical pathology and pharmacology, 1993, Volume: 80, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Formaldehyde; Injections, Intraperitoneal; Injections, Spinal; Male; Mexiletine; Mice; Mice, Inbred ICR; Nociceptors; Pain; Somatostatin; Streptozocin; Substance P

1993
Further evidence that substance P is a mediator of both neurogenic inflammation and pain: two phenomena inhibited either by postsynaptic blockade of NK1 receptors or by presynaptic action of opioid receptor agonists.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Analgesics; Animals; Anticonvulsants; Electric Stimulation; Formaldehyde; Indoles; Inflammation; Isoindoles; Male; Mice; Mice, Inbred Strains; Morphine; Pain; Peripheral Nerves; Pyrroles; Rats; Rats, Sprague-Dawley; Substance P; Thiophenes

1993
Antinociceptive effects in the formalin and capsaicin tests after intrathecal administration of substance P analogues in mice.
    European journal of pharmacology, 1993, Sep-21, Volume: 242, Issue:1

    Topics: Analgesics; Animals; Capsaicin; Drug Interactions; Formaldehyde; Injections, Spinal; Male; Mice; Naloxone; Pain; Substance P

1993
The analgesia induced by intrathecal injection of ruthenium red.
    Pain, 1993, Volume: 54, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Capsaicin; Formaldehyde; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Nociceptors; Pain; Pain Measurement; Ruthenium Red; Substance P

1993
N-(2-hydroxyethyl)hexadecanamide is orally active in reducing edema formation and inflammatory hyperalgesia by down-modulating mast cell activation.
    European journal of pharmacology, 1996, Apr-11, Volume: 300, Issue:3

    Topics: Amides; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cell Degranulation; Dextrans; Ear, External; Edema; Endocannabinoids; Ethanolamines; Evans Blue; Excipients; Extravasation of Diagnostic and Therapeutic Materials; Female; Formaldehyde; Hyperalgesia; Male; Mast Cells; Mice; Mice, Inbred BALB C; Palmitic Acids; Passive Cutaneous Anaphylaxis; Rats; Rats, Wistar; Substance P

1996
The spinal contribution of substance P to the generation and maintenance of inflammatory hyperalgesia in the rat.
    Pain, 1996, Volume: 67, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Biphenyl Compounds; Carrageenan; Dose-Response Relationship, Drug; Foot; Formaldehyde; Hot Temperature; Hyperalgesia; Inflammation; Male; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

1996
Enantioselective inhibition of the formalin paw late phase by the NK1 receptor antagonist L-733,060 in gerbils.
    Pain, 1996, Volume: 67, Issue:1

    Topics: Animals; Female; Foot; Formaldehyde; Gerbillinae; Injections; Male; Motor Activity; Neurokinin-1 Receptor Antagonists; Nociceptors; Peptide Fragments; Piperidines; Stereoisomerism; Substance P; Time Factors

1996
Nitric oxide mediates long-term hyperalgesic and antinociceptive effects of the N-terminus of substance P in the formalin assay in mice.
    Pain, 1996, Volume: 67, Issue:2-3

    Topics: Analgesics; Animals; Arginine; Enzyme Inhibitors; Formaldehyde; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Measurement; Peptide Fragments; Stereoisomerism; Substance P; Time Factors

1996
LY303870, a centrally active neurokinin-1 antagonist with a long duration of action.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: Animals; Drug Synergism; Electroshock; Formaldehyde; Guinea Pigs; Humans; Indoles; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Motor Activity; Neurokinin-1 Receptor Antagonists; Pain; Peptide Fragments; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Reflex, Startle; Species Specificity; Spinal Cord; Substance P

1997
Spinal neurokinin NK1 receptor down-regulation and antinociception: effects of spinal NK1 receptor antisense oligonucleotides and NK1 receptor occupancy.
    Journal of neurochemistry, 1998, Volume: 70, Issue:2

    Topics: Animals; Down-Regulation; Formaldehyde; Indoles; Injections, Spinal; Isoindoles; Male; N-Methylaspartate; Oligonucleotides, Antisense; Pain; Pain Threshold; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P

1998
Tachykinin NK-1 and NK-3 selective agonists induce analgesia in the formalin test for tonic pain following intra-VTA or intra-accumbens microinfusions.
    Behavioural brain research, 1997, Volume: 89, Issue:1-2

    Topics: Amphetamine; Analgesics, Non-Narcotic; Animals; Central Nervous System Stimulants; Formaldehyde; Male; Microinjections; Nucleus Accumbens; Pain Measurement; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Ventral Tegmental Area

1997
Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-03, Volume: 95, Issue:5

    Topics: Acetic Acid; Alleles; Animals; Biomarkers; Calcitonin Gene-Related Peptide; Formaldehyde; Ganglia, Spinal; Gene Deletion; In Situ Hybridization; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurokinin A; Neurons; Pain; Spinal Cord; Substance P

1998
Altered nociception, analgesia and aggression in mice lacking the receptor for substance P.
    Nature, 1998, Mar-26, Volume: 392, Issue:6674

    Topics: Aggression; Analgesia; Analgesics, Opioid; Animals; Electric Stimulation; Electromyography; Female; Formaldehyde; Gene Targeting; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Morphine; Mutagenesis; Neuritis; Pain; Pain Threshold; Physical Stimulation; Receptors, Neurokinin-1; Stress, Physiological; Substance P

1998
Ginsenosides induce differential antinociception and inhibit substance P induced-nociceptive response in mice.
    Life sciences, 1998, Volume: 62, Issue:21

    Topics: Analgesia; Animals; Central Nervous System Agents; Female; Formaldehyde; Ginsenosides; Mice; Nociceptors; Pain; Panax; Plants, Medicinal; Saponins; Substance P

1998
Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae).
    Life sciences, 1998, Volume: 63, Issue:5

    Topics: Abdominal Pain; Acetic Acid; Animals; Bradykinin; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Hyperalgesia; Male; Mice; Motor Activity; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Sesquiterpenes; Substance P; Zymosan

1998
Reduced nociceptive behavior in islet amyloid polypeptide (amylin) knockout mice.
    Brain research. Molecular brain research, 1998, Dec-10, Volume: 63, Issue:1

    Topics: Amyloid; Animals; Ankle Joint; Behavior, Animal; Calcitonin Gene-Related Peptide; Disinfectants; Formaldehyde; Freund's Adjuvant; Ganglia, Spinal; Islet Amyloid Polypeptide; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuritis; Neurons, Afferent; Nociceptors; Somatosensory Cortex; Spinal Cord; Substance P

1998
Evidence for tonic activation of NK-1 receptors during the second phase of the formalin test in the Rat.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Aug-01, Volume: 19, Issue:15

    Topics: Animals; Autoradiography; Behavior, Animal; Electrophysiology; Formaldehyde; Injections, Intravenous; Injections, Spinal; Injections, Subcutaneous; Male; Neurons; Nociceptors; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Skin; Spinal Cord; Substance P; Time Factors

1999
Central and peripheral expression of neurokinin-1 and neurokinin-3 receptor and substance P-encoding messenger RNAs: peripheral regulation during formalin-induced inflammation and lack of neurokinin receptor expression in primary afferent sensory neurons.
    Neuroscience, 1999, Volume: 93, Issue:1

    Topics: Animals; Central Nervous System; Formaldehyde; In Situ Hybridization; Male; Neuritis; Neurons, Afferent; Peripheral Nervous System; Plasmids; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Ribonucleases; RNA Probes; RNA, Messenger; Substance P; Tissue Distribution; Transcription, Genetic

1999
Elevated substance-P-like immunoreactivity levels in spinal dialysates during the formalin test in normal and diabetic rats.
    Brain research, 2000, Feb-21, Volume: 856, Issue:1-2

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Formaldehyde; Hindlimb; Hot Temperature; Pain; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Reference Values; Spinal Cord; Substance P

2000
Differential roles of spinal cholera toxin- and pertussis toxin-sensitive G proteins in nociceptive responses caused by formalin, capsaicin, and substance P in mice.
    Brain research bulletin, 2001, Mar-15, Volume: 54, Issue:5

    Topics: Animals; Behavior, Animal; Capsaicin; Cholera Toxin; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; GTP-Binding Proteins; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Neurons; Nociceptors; Pain; Pain Measurement; Pain Threshold; Pertussis Toxin; Spinal Cord; Substance P; Synaptic Transmission; Virulence Factors, Bordetella

2001
Spinal substance P immunoreactivity is enhanced by acute chemical stimulation of the rat prostate.
    Urology, 2002, Volume: 59, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Fixatives; Formaldehyde; Lumbar Vertebrae; Male; Pain; Prostate; Prostatic Diseases; Rats; Rats, Sprague-Dawley; Sacrococcygeal Region; Spinal Cord; Stimulation, Chemical; Substance P; Sulfonamides; Tamsulosin; Up-Regulation

2002
Projection neurons in lamina I of rat spinal cord with the neurokinin 1 receptor are selectively innervated by substance p-containing afferents and respond to noxious stimulation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, May-15, Volume: 22, Issue:10

    Topics: Animals; Axons; Calcitonin Gene-Related Peptide; Cell Count; Cholera Toxin; Dendrites; Fluorescent Dyes; Formaldehyde; Immunohistochemistry; Male; Microscopy, Confocal; Microscopy, Electron; Neurons; Neurons, Afferent; Pain Measurement; Proto-Oncogene Proteins c-fos; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Neurokinin-1; Spinal Cord; Stilbamidines; Substance P; Synapses

2002
Modulation of inflammatory paw oedema by cysteamine in the rat.
    Pharmacological research, 2002, Volume: 45, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Celecoxib; Corticotropin-Releasing Hormone; Cystamine; Edema; Formaldehyde; Histamine; Indomethacin; Pyrazoles; Rats; Somatostatin; Substance P; Sulfonamides; Tumor Necrosis Factor-alpha

2002
Evidence for the involvement of glutamatergic receptors in the antinociception caused in mice by the sesquiterpene drimanial.
    Neuropharmacology, 2002, Volume: 43, Issue:3

    Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drimys; Excitatory Amino Acids; Formaldehyde; Glutamic Acid; Injections, Spinal; Male; Mice; Morphine; Pain Measurement; Postural Balance; Psychomotor Performance; Receptors, Glutamate; Sesquiterpenes; Substance P

2002
Endomorphin-2 is not released from rat spinal dorsal horn in response to intraplantar formalin.
    Neuroscience letters, 2002, Dec-06, Volume: 334, Issue:1

    Topics: Animals; Female; Formaldehyde; Genes, fos; Hindlimb; Male; Oligopeptides; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Substance P

2002
Substance P gene expression in acute experimental colitis.
    Regulatory peptides, 1995, Sep-22, Volume: 59, Issue:1

    Topics: Acute Disease; Animals; Colitis; Colon; Disease Models, Animal; Formaldehyde; Ganglia, Spinal; Gene Expression Regulation; Muscle, Smooth; Rabbits; Substance P

1995
The algogenic-induced nociceptive flexion test in mice: studies on sensitivity of the test and stress on animals.
    Brain research bulletin, 2003, May-15, Volume: 60, Issue:3

    Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Bites and Stings; Bradykinin; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Epoprostenol; Formaldehyde; Immobilization; Male; Mice; Pain; Pain Measurement; Peripheral Nervous System; Prostaglandins F; Reflex; Sensitivity and Specificity; Stress, Physiological; Substance P

2003
Sialorphin, a natural inhibitor of rat membrane-bound neutral endopeptidase that displays analgesic activity.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Jul-08, Volume: 100, Issue:14

    Topics: Amino Acid Sequence; Analgesics; Animals; Enkephalin, Methionine; Formaldehyde; Glycopeptides; Kidney; Leucine; Male; Membrane Proteins; Molecular Sequence Data; Naltrexone; Neprilysin; Pain; Pain Measurement; Prostate; Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Salivary Proteins and Peptides; Spinal Cord; Submandibular Gland; Substance P; Thiorphan; Wounds and Injuries

2003
Enhanced disease and pulmonary eosinophilia associated with formalin-inactivated respiratory syncytial virus vaccination are linked to G glycoprotein CX3C-CX3CR1 interaction and expression of substance P.
    Journal of virology, 2003, Volume: 77, Issue:18

    Topics: Amino Acid Motifs; Animals; CD4-Positive T-Lymphocytes; Cell Movement; Chemokines; Chemokines, CX3C; CX3C Chemokine Receptor 1; Female; Formaldehyde; Membrane Proteins; Mice; Mice, Inbred BALB C; Pulmonary Eosinophilia; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Chemokine; Respiratory Syncytial Viruses; RNA, Messenger; Substance P; Vaccination; Vaccines, Inactivated; Viral Proteins; Viral Vaccines

2003
Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing.
    Journal of neurochemistry, 2003, Volume: 86, Issue:6

    Topics: Animals; Cyclooxygenase 2; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Formaldehyde; Hyperalgesia; Imidazoles; Inflammation; Injections, Spinal; Isoenzymes; Male; Microglia; Mitogen-Activated Protein Kinases; Neuralgia; p38 Mitogen-Activated Protein Kinases; Pain Measurement; Pain Threshold; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

2003
Antinociceptive profiles of crude extract from roots of Angelica gigas NAKAI in various pain models.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:9

    Topics: Administration, Oral; Analgesics; Angelica; Animals; Capsaicin; Cytokines; Excitatory Amino Acids; Formaldehyde; Hot Temperature; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Plant Extracts; Plant Roots; Postural Balance; Reaction Time; Substance P

2003
The influence of inflammation on the expression of neuropeptides in the ileum-projecting primary sensory neurones in the pig.
    Folia morphologica, 2003, Volume: 62, Issue:3

    Topics: Animals; Calcitonin Gene-Related Peptide; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Fluorescent Dyes; Formaldehyde; Galanin; Ganglia, Spinal; Ileitis; Ileum; Neurons, Afferent; Neuropeptide Y; Neuropeptides; Polymers; Somatostatin; Substance P; Sus scrofa; Thoracic Vertebrae; Up-Regulation; Vasoactive Intestinal Peptide; Visceral Afferents

2003
Reduced inflammatory hyperalgesia with preservation of acute thermal nociception in mice lacking cGMP-dependent protein kinase I.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Mar-02, Volume: 101, Issue:9

    Topics: Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Formaldehyde; Hot Temperature; Hyperalgesia; Inflammation; Mice; Mice, Knockout; Neurons; Pain; Reaction Time; Substance P; Thionucleotides

2004
Leukocyte recruitment to peritoneal cavity of rats following formalin injection: role of tachykinin receptors.
    Journal of pharmacological sciences, 2004, Volume: 94, Issue:4

    Topics: Animals; Benzamides; Cell Movement; Dose-Response Relationship, Drug; Female; Formaldehyde; Injections, Intraperitoneal; Leukocytes; Models, Biological; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peritoneal Cavity; Peritoneal Lavage; Piperidines; Quinuclidines; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P; Time Factors

2004
Increased substance P and tumor necrosis factor-alpha level in the paws following formalin injection in rat tail.
    Brain research, 2004, Sep-03, Volume: 1019, Issue:1-2

    Topics: Animals; Forelimb; Formaldehyde; Hindlimb; Male; Rats; Substance P; Tumor Necrosis Factor-alpha

2004
[Effect of tianyuan ketong recipe on the pain behavior, c-fos expression and P substance contents in dorsal horn of spinal cord in formalin induced pain model rats].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2004, Volume: 24, Issue:11

    Topics: Analgesics, Non-Narcotic; Animals; Drugs, Chinese Herbal; Female; Formaldehyde; Immunohistochemistry; Male; Oncogene Proteins v-fos; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

2004
Intrathecally-administered histamine facilitates nociception through tachykinin NK1 and histamine H1 receptors: a study in histidine decarboxylase gene knockout mice.
    European journal of pharmacology, 2005, Oct-17, Volume: 522, Issue:1-3

    Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Behavior, Animal; Capsaicin; Excitatory Amino Acid Antagonists; Female; Formaldehyde; Histamine; Histidine Decarboxylase; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Peptide Fragments; Pyrrolidonecarboxylic Acid; Receptors, Histamine H1; Receptors, Neurokinin-1; Substance P; Time Factors

2005
Stellate ganglion block inhibits formalin-induced nociceptive responses: mechanism of action.
    European journal of anaesthesiology, 2005, Volume: 22, Issue:12

    Topics: Analgesia; Anesthetics, Local; Animals; Autonomic Nerve Block; Behavior, Animal; Bupivacaine; Formaldehyde; Male; Norepinephrine; Pain; Pain Management; Pain Measurement; Proto-Oncogene Proteins c-fos; Rabbits; Spinal Cord; Stellate Ganglion; Substance P

2005
Potent analgesic effects of a putative sodium channel blocker M58373 on formalin-induced and neuropathic pain in rats.
    European journal of pharmacology, 2006, May-01, Volume: 536, Issue:3

    Topics: Analgesics; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Formaldehyde; Ganglia, Spinal; Hot Temperature; Hyperalgesia; Male; Mexiletine; Motor Activity; Neuralgia; Nitriles; Pain; Pain Measurement; Piperidines; Rats; Rats, Wistar; Sodium Channel Blockers; Stress, Mechanical; Substance P; Veratridine

2006
Formalin produces depolarizations in human airway smooth muscle in vitro.
    Toxicology and industrial health, 2006, Volume: 22, Issue:2

    Topics: Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Capsaicin; Electrophysiology; Formaldehyde; Humans; In Vitro Techniques; Irritants; Membrane Potentials; Muscle, Smooth; Neuromuscular Depolarizing Agents; Substance P; Trachea

2006
Role of calcitonin gene-related peptide and substance P in different models of pain.
    Cephalalgia : an international journal of headache, 2008, Volume: 28, Issue:2

    Topics: Animals; Calcitonin Gene-Related Peptide; Central Nervous System; Formaldehyde; Hyperalgesia; Immunohistochemistry; Injections, Intraperitoneal; Injections, Subcutaneous; Lumbosacral Region; Male; Nitroglycerin; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Substance P; Trigeminal Caudal Nucleus

2008
The differential effect of morphine and beta-endorphin administered intracerebroventricularly on pERK and pCaMK-II expression induced by various nociceptive stimuli in mice brains.
    Neuropeptides, 2008, Volume: 42, Issue:3

    Topics: Analgesics, Opioid; Animals; beta-Endorphin; Blotting, Western; Brain Chemistry; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Extracellular Signal-Regulated MAP Kinases; Formaldehyde; Immunohistochemistry; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Pain; Paraventricular Hypothalamic Nucleus; Substance P

2008
The differential effects of acetaminophen on lipopolysaccharide induced hyperalgesia in various mouse pain models.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 91, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Formaldehyde; Glutamic Acid; Hyperalgesia; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Pain Measurement; Substance P

2008
Dexmedetomidine and ST-91 analgesia in the formalin model is mediated by alpha2A-adrenoceptors: a mechanism of action distinct from morphine.
    British journal of pharmacology, 2008, Volume: 155, Issue:7

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Gene Expression Regulation; Injections, Spinal; Male; Morphine; Pain; Pain Measurement; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Neurokinin-1; Substance P

2008
Substance P expression in the distal cerebrospinal fluid-contacting neurons and spinal trigeminal nucleus in formalin-induced the orofacial inflammatory pain in rats.
    Brain research bulletin, 2009, Mar-16, Volume: 78, Issue:4-5

    Topics: Animals; Facial Pain; Formaldehyde; Immunohistochemistry; Inflammation; Injections, Subcutaneous; Male; Microscopy, Immunoelectron; Neurons; Pain Measurement; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Substance P; Trigeminal Nucleus, Spinal

2009
Development of mechanisms associated with neurogenic-mediated skin inflammation during the growth of rats.
    Pediatric research, 2010, Volume: 67, Issue:4

    Topics: Age Factors; Animals; Capsaicin; Cell Degranulation; Female; Fixatives; Formaldehyde; Male; Mast Cells; Nerve Fibers, Unmyelinated; Neurogenic Inflammation; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Neurokinin-1; Sensory System Agents; Skin; Substance P

2010
Antinociceptive effect of vinpocetine--a comprehensive survey.
    Ideggyogyaszati szemle, 2010, May-30, Volume: 63, Issue:5-6

    Topics: Acid Phosphatase; Analgesics; Animals; Calcitonin Gene-Related Peptide; Densitometry; Formaldehyde; Male; Nerve Growth Factor; Neuroprotective Agents; Pain; Pain Measurement; Phosphoric Monoester Hydrolases; Rats; Rats, Wistar; Spinal Cord; Substance P; Vinca Alkaloids

2010
TRPA1 receptors mediate environmental irritant-induced meningeal vasodilatation.
    Pain, 2011, Volume: 152, Issue:1

    Topics: Acetanilides; Acrolein; Animals; Animals, Newborn; Ankyrins; Calcitonin Gene-Related Peptide; Calcium Channels; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Formaldehyde; Garlic; Laser-Doppler Flowmetry; Meningeal Arteries; Mustard Plant; Neurons; Peptide Fragments; Plant Oils; Purines; Rats; Sensory System Agents; Substance P; Trigeminal Ganglion; TRPA1 Cation Channel; TRPC Cation Channels; Vasodilation

2011
Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Feb-09, Volume: 31, Issue:6

    Topics: Androstadienes; Animals; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Formaldehyde; Gene Expression Regulation, Enzymologic; Hyperalgesia; Inflammation; Male; Nerve Tissue Proteins; Pain Measurement; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reaction Time; Signal Transduction; Sirolimus; Spinal Cord; Statistics, Nonparametric; Substance P; Time Factors; TOR Serine-Threonine Kinases; Wortmannin

2011
Activation of spinal mu- and delta-opioid receptors potently inhibits substance P release induced by peripheral noxious stimuli.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Sep-14, Volume: 31, Issue:37

    Topics: Animals; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Formaldehyde; Injections, Spinal; Male; Mice; Mice, Knockout; Neurons; Neurons, Afferent; Oligopeptides; Pain; Pain Measurement; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Substance P; Tachykinins

2011
Knockdown of the tachykinin neurokinin 1 receptor by intrathecal administration of small interfering RNA in rats.
    European journal of pharmacology, 2011, Nov-30, Volume: 670, Issue:2-3

    Topics: Animals; Base Sequence; Behavior, Animal; Carrageenan; Formaldehyde; Gene Expression Regulation; Gene Knockdown Techniques; Genetic Vectors; Hyperalgesia; Inflammation; Injections, Spinal; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Small Interfering; Sendai virus; Spinal Cord; Substance P

2011
Suppressive effects of glycyrrhetinic acid derivatives on tachykinin receptor activation and hyperalgesia.
    Journal of pharmacological sciences, 2011, Volume: 117, Issue:3

    Topics: Analgesics; Animals; Calcium; Capsaicin; CHO Cells; Cricetinae; Disease Models, Animal; Formaldehyde; Glycyrrhetinic Acid; Hot Temperature; Humans; Hyperalgesia; Inflammation; Ligation; Male; Neuralgia; Neurokinin A; Neurokinin B; Pain; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Sciatic Nerve; Substance P

2011
Pharmacological characteristics of endokinin C/D-derived peptides in nociceptive and inflammatory processing in rats.
    Peptides, 2011, Volume: 32, Issue:12

    Topics: Amino Acid Sequence; Amino Acids; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Formaldehyde; Humans; Hyperalgesia; Immunohistochemistry; Inflammation; Injections, Subcutaneous; Male; Nociceptive Pain; Pain Measurement; Peptide Fragments; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Substance P; Tachykinins; Time Factors; Tryptophan

2011
Effect of exposure to volatile organic compounds (VOCs) on airway inflammatory response in mice.
    The Journal of toxicological sciences, 2012, Volume: 37, Issue:4

    Topics: Administration, Inhalation; Air Pollution, Indoor; Animals; Benzene; Bronchoalveolar Lavage Fluid; China; Formaldehyde; Interferon-gamma; Interleukin-6; Lung; Male; Mice; Mice, Inbred Strains; Neurotrophin 3; Oxidative Stress; Pneumonia; Reactive Oxygen Species; Signal Transduction; Substance P; Toluene; Volatile Organic Compounds; Xylenes

2012
Cellular mechanism underlying formaldehyde-stimulated Cl- secretion in rat airway epithelium.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anions; Biological Transport; Capsaicin; Cells, Cultured; Chlorides; Colforsin; Epinephrine; Epithelial Cells; Formaldehyde; Imines; Male; Nerve Endings; ortho-Aminobenzoates; Quinuclidines; Rats; Respiratory Mucosa; Substance P; Trachea; TRPV Cation Channels

2013
Volume transmission of substance P in striatum induced by intraplantar formalin injection attenuates nociceptive responses via activation of the neurokinin 1 receptor.
    Journal of pharmacological sciences, 2013, Volume: 121, Issue:4

    Topics: Analgesia; Animals; Biphenyl Compounds; Corpus Striatum; Formaldehyde; Genes, fos; Genes, Immediate-Early; Injections; Male; Neurokinin-1 Receptor Antagonists; Nociception; Protein Precursors; Rats; Rats, Wistar; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Tachykinins; Time Factors; Up-Regulation

2013
Acute colitis induces neurokinin 1 receptor internalization in the rat lumbosacral spinal cord.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Acute Disease; Animals; Colitis; Colon; Formaldehyde; Gene Expression; Lumbosacral Region; Male; Neurokinin-1 Receptor Antagonists; Neurons; Nociception; Nociceptive Pain; Protein Transport; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P; Tryptophan

2013
Role of transient receptor potential ion channels and evoked levels of neuropeptides in a formaldehyde-induced model of asthma in BALB/c mice.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Acetanilides; Animals; Asthma; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Formaldehyde; Immunoglobulin E; Immunohistochemistry; Interleukin-1beta; Interleukin-4; Interleukin-6; Lung; Male; Mice; Mice, Inbred BALB C; Neuropeptides; Ovalbumin; Purines; Substance P; Transient Receptor Potential Channels

2013
Antinociceptive profiles and mechanisms of orally administered coumarin in mice.
    Biological & pharmaceutical bulletin, 2013, Volume: 36, Issue:6

    Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Behavior, Animal; Coumarins; Formaldehyde; Glutamic Acid; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Pain; Receptors, Opioid; Substance P

2013
Sex differences in formalin-evoked primary afferent release of substance P.
    European journal of pain (London, England), 2014, Volume: 18, Issue:1

    Topics: Animals; Estradiol; Estrous Cycle; Female; Fluorescent Antibody Technique; Formaldehyde; Image Processing, Computer-Assisted; Immunohistochemistry; Male; Microscopy, Confocal; Neurons, Afferent; Orchiectomy; Ovariectomy; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Sex Characteristics; Substance P

2014
Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.
    European journal of pharmacology, 2014, Aug-05, Volume: 736

    Topics: Acute Pain; Acyclic Monoterpenes; Analgesics; Animals; Capsaicin; Chronic Pain; Excitatory Amino Acids; Formaldehyde; Glutamic Acid; Hyperalgesia; Ischemia; Ketanserin; Male; Mice; Monoterpenes; Neuralgia; Pain, Postoperative; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Stomach Ulcer; Substance P; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2014
Hemokinin-1 mediates pruriceptive processing in the rat spinal cord.
    Neuroscience, 2014, Sep-26, Volume: 277

    Topics: Animals; Disease Models, Animal; Formaldehyde; Histamine; Immunohistochemistry; Male; Nociception; Pain; Proto-Oncogene Proteins c-fos; Pruritus; Rats, Sprague-Dawley; Serotonin; Spinal Cord; Substance P; Tachykinins

2014
Neurochemical properties of BDNF-containing neurons projecting to rostral ventromedial medulla in the ventrolateral periaqueductal gray.
    Frontiers in neural circuits, 2014, Volume: 8

    Topics: Animals; Astrocytes; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Disease Models, Animal; Formaldehyde; Male; Medulla Oblongata; Microglia; Neural Pathways; Neurons; Neurotensin; Nitric Oxide Synthase; Pain; Parvalbumins; Periaqueductal Gray; Rats, Sprague-Dawley; Receptor, trkB; RNA, Messenger; Serotonin; Substance P; Tyrosine Decarboxylase

2014
Antinociceptive profiles and mechanisms of centrally administered oxyntomodulin in various mouse pain models.
    Neuropeptides, 2018, Volume: 68

    Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Cytokines; Disease Models, Animal; Formaldehyde; Glutamic Acid; Injections, Intraventricular; Injections, Spinal; Male; Mice, Inbred ICR; Nociception; Oxyntomodulin; Pain; Rotarod Performance Test; Spinal Cord; Substance P

2018