substance p has been researched along with endomorphin 2 in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (7.14) | 18.2507 |
| 2000's | 17 (60.71) | 29.6817 |
| 2010's | 9 (32.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bushy, TM; Fairbanks, CA; Laughlin, TM; Nguyen, HO; Stone, LS; Wessendorf, MW; Wilcox, GL | 1 |
| Gerall, AA; Kastin, AJ; Martin-Schild, S; Zadina, JE | 1 |
| Beinborn, M; Carr, DB; Foran, SE; Kopin, AS; Kream, RM; Lipkowski, AW; Marchand, JE; Maszczynska, I; Misicka, A | 2 |
| Kastin, AJ; Martin-Schild, S; Smith, RR; Zadina, JE | 1 |
| Puskár, Z; Sakamoto, H; Spike, RC; Stewart, W; Todd, AJ; Watt, C | 1 |
| Dun, NJ; Hua, F; Ricketts, BA; Williams, CA | 1 |
| Fujimoto, JM; Leitermann, RJ; Sun, HS; Thompson, J; Tseng, LF; Wu, HE | 1 |
| Basbaum, AI; Julius, D; Sanderson Nydahl, K; Skinner, K | 1 |
| Clithero, AD; Leitermann, RJ; Sun, HS; Terashvili, M; Tseng, LF; Wu, HE | 1 |
| Buschnack, SH; Kremmer, S; Muth-Selbach, U; Selbach, JM; Steuhl, KP | 1 |
| Bailey, AL; Dorfman, HN; Ribeiro-da-Silva, A; St Louis, M; Zadina, JE | 1 |
| Bonney, I; Carr, DB; Kosson, P; Lipkowski, AW | 1 |
| Carrega, L; Devaux, C; Fajloun, Z; Fenouillet, E; Guieu, R; Marguet, D; Sabatier, JM; Sauze, N | 1 |
| Botros, M; Frändberg, PA; Hallberg, M; Johansson, T; Le Grevès, P; Lindeberg, G; Nyberg, F; Tömböly, C; Tóth, G; Zhou, Q | 1 |
| Greenwell, TN; Inglis, FM; Martin-Schild, S; Zadina, JE | 1 |
| Janecka, A; Zubrzycka, M | 1 |
| Botros, M; Hallberg, M; Johansson, T; Le Grevès, P; Lindeberg, G; Nyberg, F; Tömböly, C; Tóth, G; Zhou, Q | 1 |
| Chen, T; Li, YQ; Niu, L; Wang, YY | 1 |
| Brancati, SB; Gyires, K; Németh, J; Zádori, ZS | 1 |
| Mizoguchi, H; Sakurada, S; Sakurada, T; Sato, T; Takagi, H; Watanabe, C; Yonezawa, A | 1 |
| Dong, YL; Huang, J; Li, YQ; Lu, YC; Luo, DS; Wang, W; Wang, YY; Wei, YY; Wu, SX; Wu, ZY; Yanagawa, Y | 1 |
| Dai, GH; Deng, WT; Guo, XD; Huang, KB; Luo, GQ; Pan, SY; Peng, KR; Qian, NS; Wu, XN; Xiang, W; Yang, HJ; Zhang, T | 1 |
| Gao, CJ; He, ZY; Jiao, XW; Kou, ZZ; Li, JP; Li, YQ; Wu, ZY; Zhang, LX; Zhang, T | 1 |
| Appleyard, CB; Cruz, ML; Hernandez, S; Seguinot, II; Torres-Reveron, A | 1 |
| Hallberg, M; Sandstrom, A | 1 |
| Botros, M; Fransson, R; Hallberg, M; Lindeberg, G; Nyberg, F; Sandström, A; Sköld, C | 1 |
| Diwakarla, S; Fransson, R; Gaugaz, FZ; Hallberg, M; Jonsson, A; Karlgren, M; Lesniak, A; Nyberg, F; Sandström, A; Skogh, A; Sköld, C; Svensson, R | 1 |
1 review(s) available for substance p and endomorphin 2
| Article | Year |
|---|---|
From the Anti-Nociceptive Substance P Metabolite Substance P (1-7) to Small Peptidomimetics.
Topics: Analgesics; Animals; Binding Sites; Dipeptides; Humans; Hyperalgesia; Neuralgia; Oligopeptides; Peptide Fragments; Peptidomimetics; Protein Conformation; Structure-Activity Relationship; Substance P | 2018 |
27 other study(ies) available for substance p and endomorphin 2
| Article | Year |
|---|---|
Spinal analgesic actions of the new endogenous opioid peptides endomorphin-1 and -2.
Topics: Analgesics, Opioid; Animals; Cattle; Drug Tolerance; Hot Temperature; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Oligopeptides; Receptors, Opioid, mu; Substance P | 1997 |
Endomorphin-2 is an endogenous opioid in primary sensory afferent fibers.
Topics: Analgesics, Opioid; Animals; Brain Chemistry; Nerve Fibers; Neurons, Afferent; Neurotransmitter Agents; Oligopeptides; Rats; Receptors, Opioid, mu; Substance P | 1998 |
A substance P-opioid chimeric peptide as a unique nontolerance-forming analgesic.
Topics: Analgesics; Animals; Drug Design; Male; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Substance P | 2000 |
Inhibition of morphine tolerance development by a substance P-opioid peptide chimera.
Topics: Analgesics, Opioid; Animals; Drug Tolerance; Indoles; Isoindoles; Male; Morphine; Naltrexone; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Structure-Activity Relationship; Substance P | 2000 |
Decreases in endomorphin-2-like immunoreactivity concomitant with chronic pain after nerve injury.
Topics: Animals; Calcitonin Gene-Related Peptide; Chronic Disease; Down-Regulation; Functional Laterality; Hyperalgesia; Immunohistochemistry; Ligation; Male; Mice; Mice, Inbred ICR; Nerve Crush; Neuralgia; Oligopeptides; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Posterior Horn Cells; Reaction Time; Sciatic Nerve; Substance P | 2001 |
MOR-1-immunoreactive neurons in the dorsal horn of the rat spinal cord: evidence for nonsynaptic innervation by substance P-containing primary afferents and for selective activation by noxious thermal stimuli.
Topics: Afferent Pathways; Animals; Cell Communication; Female; Hot Temperature; Hyperalgesia; Male; Nerve Fibers; Nociceptors; Oligopeptides; Pain; Posterior Horn Cells; Presynaptic Terminals; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Opioid, mu; Substance P; Synaptic Transmission | 2002 |
Endomorphin-2 is not released from rat spinal dorsal horn in response to intraplantar formalin.
Topics: Animals; Female; Formaldehyde; Genes, fos; Hindlimb; Male; Oligopeptides; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Substance P | 2002 |
Nonopioidergic mechanism mediating morphine-induced antianalgesia in the mouse spinal cord.
Topics: Analgesia; Animals; beta-Endorphin; Dizocilpine Maleate; Drug Interactions; Drug Tolerance; Dynorphins; Enkephalins; Male; Mice; Morphine; Naloxone; Naltrexone; Oligopeptides; Pain; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Substance P | 2004 |
Co-localization of endomorphin-2 and substance P in primary afferent nociceptors and effects of injury: a light and electron microscopic study in the rat.
Topics: Afferent Pathways; Animals; Axotomy; Biomarkers; Calcitonin Gene-Related Peptide; Cell Size; Functional Laterality; Ganglia, Spinal; Glycoproteins; Immunohistochemistry; Intermediate Filament Proteins; Lectins; Male; Membrane Glycoproteins; Mice; Mice, Knockout; Microscopy, Immunoelectron; Nerve Tissue Proteins; Neurofilament Proteins; Neurons, Afferent; Oligopeptides; Peripherins; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Substance P; Versicans | 2004 |
Differential mechanisms of antianalgesia induced by endomorphin-1 and endomorphin-2 in the ventral periaqueductal gray of the rat.
Topics: Analgesia; Animals; beta-Endorphin; Cholecystokinin; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Morphine; Naloxone; Oligopeptides; Periaqueductal Gray; Rats; Receptors, Opioid, mu; Substance P | 2005 |
Substance P and opioid peptidergic innervation of the anterior eye segment of the rat: an immunohistochemical study.
Topics: Animals; Anterior Eye Segment; Ciliary Body; Conjunctiva; Cornea; Enkephalin, Leucine; Enkephalin, Methionine; Immunohistochemistry; Iris; Nociceptin; Oligopeptides; Opioid Peptides; Rats; Rats, Sprague-Dawley; Sclera; Substance P; Trabecular Meshwork | 2005 |
Postnatal development of ectopic sensory fibers containing endomorphin-2 in the white matter of the spinal cord of a transgenic mouse expressing nerve growth factor in oligodendrocytes.
Topics: Animals; Animals, Newborn; Female; Immunohistochemistry; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Nerve Growth Factor; Neurons, Afferent; Oligodendroglia; Oligopeptides; Pain; Receptors, Opioid, mu; Spinal Cord; Substance P | 2005 |
Endomorphins interact with tachykinin receptors.
Topics: Animals; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Molecular Structure; Neurokinin-1 Receptor Antagonists; Oligopeptides; Peptide Fragments; Radioligand Assay; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Opioid; Receptors, Tachykinin; Substance P | 2005 |
CD26 modulates nociception in mice via its dipeptidyl-peptidase IV activity.
Topics: Analysis of Variance; Androstanes; Animals; Benzimidazoles; Dipeptidyl Peptidase 4; Dose-Response Relationship, Drug; Female; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Pain; Pain Measurement; Reaction Time; Substance P | 2006 |
Endomorphin-1 and endomorphin-2 differentially interact with specific binding sites for substance P (SP) aminoterminal SP1-7 in the rat spinal cord.
Topics: Animals; Binding Sites; Cell Line, Tumor; Male; Neurotransmitter Agents; Oligopeptides; Peptide Fragments; Protein Binding; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 2006 |
Colocalization and shared distribution of endomorphins with substance P, calcitonin gene-related peptide, gamma-aminobutyric acid, and the mu opioid receptor.
Topics: Animals; Brain; Calcitonin Gene-Related Peptide; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Neurons; Oligopeptides; Opioid Peptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord; Substance P; Tissue Distribution | 2007 |
Interactions of galanin with endomorphin-2, vasopressin and oxytocin in nociceptive modulation of the trigemino-hypoglossal reflex in rats.
Topics: Animals; Arginine Vasopressin; Cerebral Ventricles; Dental Pulp; Electric Stimulation; Galanin; Hypoglossal Nerve; Male; Narcotic Antagonists; Oligopeptides; Oxytocin; Pain; Pain Measurement; Perfusion; Rats; Rats, Long-Evans; Reflex; Substance P; Tongue; Trigeminal Nerve | 2008 |
Endomorphins interact with the substance P (SP) aminoterminal SP(1-7) binding in the ventral tegmental area of the rat brain.
Topics: Analgesics, Opioid; Animals; Binding Sites; Male; Oligopeptides; Peptide Fragments; Protein Binding; Rats; Rats, Sprague-Dawley; Substance P; Ventral Tegmental Area | 2008 |
Neurochemical phenotypes of endomorphin-2-containing neurons in vagal nodose neurons of the adult rat.
Topics: Analgesics, Opioid; Animals; Antibody Specificity; Biomarkers; Biotin; Dextrans; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Immunohistochemistry; Male; Microscopy, Confocal; Neurons; Neurotransmitter Agents; Nodose Ganglion; Oligopeptides; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Substance P; Vagus Nerve | 2009 |
Substance P induces gastric mucosal protection at supraspinal level via increasing the level of endomorphin-2 in rats.
Topics: Alcohols; Animals; Calcitonin Gene-Related Peptide; Disease Models, Animal; Ethanol; Gastric Mucosa; Injections, Intraventricular; Male; Neurotransmitter Agents; Oligopeptides; Radioimmunoassay; Rats; Rats, Wistar; Stomach Ulcer; Substance P | 2013 |
Involvement of multiple µ-opioid receptor subtypes on the presynaptic or postsynaptic inhibition of spinal pain transmission.
Topics: Analgesics; Animals; Capsaicin; Male; Mice; N-Methylaspartate; Nociception; Oligopeptides; Pain; Presynaptic Terminals; Receptors, Opioid, mu; Somatostatin; Substance P; Synaptic Transmission | 2014 |
Connections between EM2- and SP-containing terminals and GABAergic neurons in the mouse spinal dorsal horn.
Topics: Animals; GABAergic Neurons; Glutamate Decarboxylase; Green Fluorescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Immunoelectron; Oligopeptides; Oncogene Proteins v-fos; Presynaptic Terminals; Spinal Cord Dorsal Horn; Substance P | 2014 |
Antinociceptive effects of endomorphin-2: suppression of substance P release in the inflammatory pain model rat.
Topics: Animals; Arthritis, Experimental; Chronic Pain; Ganglia, Spinal; Hyperalgesia; Injections, Spinal; Male; Microdialysis; Microscopy, Electron; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Nociception; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Receptors, Presynaptic; Spinal Cord; Spinal Cord Dorsal Horn; Stress, Mechanical; Substance P; Tryptophan | 2015 |
Neurochemical features of endomorphin-2-containing neurons in the submucosal plexus of the rat colon.
Topics: Animals; Biomarkers; Calcitonin Gene-Related Peptide; Choline O-Acetyltransferase; Colon; Fluorescent Antibody Technique; Intestinal Mucosa; Male; Microscopy, Confocal; Muscle, Smooth; Myenteric Plexus; Neurons; Nitric Oxide Synthase; Oligopeptides; Organ Culture Techniques; Phenotype; Phosphopyruvate Hydratase; Rats, Sprague-Dawley; Substance P; Vasoactive Intestinal Peptide | 2015 |
Impact of Psychological Stress on Pain Perception in an Animal Model of Endometriosis.
Topics: Animals; Anxiety; Corticosterone; Disease Models, Animal; Endometriosis; Enkephalins; Female; Oligopeptides; Pain Measurement; Pain Perception; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid, mu; Spinal Cord; Stress, Psychological; Substance P | 2017 |
Discovery of dipeptides with high affinity to the specific binding site for substance P1-7.
Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Dipeptides; Drug Discovery; Humans; Kinetics; Male; Molecular Structure; Peptide Fragments; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Spinal Cord; Substance P | 2010 |
An imidazole based H-Phe-Phe-NH
Topics: Amides; Animals; Cell Death; Cell Survival; Cells, Cultured; Dipeptides; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Injections, Intraperitoneal; Mice; Molecular Structure; Peptidomimetics; Rats; Spinal Nerves | 2018 |