substance p has been researched along with bradykinin in 563 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 184 (32.68) | 18.7374 |
| 1990's | 232 (41.21) | 18.2507 |
| 2000's | 111 (19.72) | 29.6817 |
| 2010's | 31 (5.51) | 24.3611 |
| 2020's | 5 (0.89) | 2.80 |
| Authors | Studies |
|---|---|
| Caló, G; Camarda, V; Fiorini, S; Guerrini, R; Marzola, E; Regoli, D; Reinscheid, RK; Rizzi, A; Ruzza, C; Salvadori, S; Trapella, C | 1 |
| Greenberg, S; Palmer, GC | 1 |
| Henry, JL | 3 |
| Innis, RB; Snyder, SH | 1 |
| Sakai, K | 1 |
| Arisawa, EA; Graeff, FG | 1 |
| Manberg, PJ; Nemeroff, CB; Osbahr, AJ; Prange, AJ | 1 |
| Kumazawa, T; Mizumura, K | 1 |
| Bennett, A | 1 |
| Mishima, Y | 1 |
| Aghajanian, GK; Guyenet, PG | 1 |
| Iizuka, R; Makino, T; Muraki, T; Yokokura, T | 1 |
| Kampmann, E; Zetler, G | 1 |
| Mills, IH; Newport, PA; Obika, LF | 2 |
| Gillespie, JS; McKnight, AT | 2 |
| Fukasawa, K; Harada, M; Kato, T; Nagatsu, I; Nagatsu, T; Sakakibara, S | 1 |
| Roberts, MH; Wright, DM | 2 |
| Barasi, S; Wright, DM | 1 |
| Brecher, AS; Burkholder, DE; Simmons, WH | 1 |
| Mutt, V; Said, SI | 1 |
| Baker, AP; Hillegass, LM; Holden, DA; Smith, WJ | 1 |
| Barabé, J; Regoli, D; Thériault, B | 1 |
| Chahl, LA | 1 |
| Juan, H; Lembeck, F; Popper, H | 1 |
| Casarini, DE; Fellows, CE; Sampaio, CA; Stella, RC | 1 |
| Beny, JL; Pacicca, C; von der Weid, PY | 1 |
| Azadzoi, KM; Brown, ML; Cohen, RA; Goldstein, I; Kim, N; Saenz de Tejada, I | 1 |
| Håkanson, R; Wallengren, J | 1 |
| Katunuma, N; Kido, H; Yamaguchi, T | 1 |
| Bertrand, C; Da Silva, A; Dhuy, J; Landry, Y; Waeldelé, F | 1 |
| de Nucci, G; Mitchell, JA; Vane, JR; Warner, TD | 1 |
| Barnes, PJ; Chung, KF; Nichol, GM; Parsons, GH | 1 |
| Bachelard, H; Bennett, T; Gardiner, SM; Kemp, PA | 1 |
| Beard, DJ; Hicks, RP; Young, JK | 1 |
| Crook, RB; Lui, GM; Polansky, JR; Song, MK; Tong, LP; Yabu, JM | 1 |
| Håkanson, R; Wang, ZY | 1 |
| Abel, S; deBlois, D; Marceau, F; Petitclerc, E; Poubelle, PE | 1 |
| Inoue, H | 1 |
| Baas, AA; Evers, NA; van der Meer, C | 1 |
| Desmazes, N; Dusser, DJ; Lacroix, H; Lockhart, A | 1 |
| Blake, DR; Cruwys, SC; Kidd, BL; Mapp, PI; Walsh, DA | 1 |
| Cocks, T; Crack, P | 1 |
| Burnstock, G; Vials, A | 1 |
| Allen, SP; Chester, AH; Luu, TN; O'Neil, GS; Schyns, CJ; Tadjkarimi, S; Yacoub, MH | 1 |
| Del Bianco, E; Geppetti, P; Lippe, IT; Maggi, CA; Santicioli, P; Sicuteri, F | 1 |
| Mantione, CR; Rodriguez, R | 1 |
| Cecconi, R; Geppetti, P; Maggi, CA; Meini, S; Nardi, M; Patacchini, R; Romani, A; Tramontana, M | 1 |
| Furukawa, T; Katsuragi, T; Tokunaga, T; Usune, S | 1 |
| Rozengurt, E; Woll, PJ | 2 |
| Sasaki, H; Sekizawa, K | 1 |
| Inoki, R | 2 |
| Kimball, ES | 1 |
| Criscuoli, M; Guelfi, M; Subissi, A | 1 |
| Levi-Schaffer, F; Shalit, M | 2 |
| Hayes, L; MacLean, DB; Wheeler, F | 1 |
| Eriksson, L; Hellberg, S; Jonsson, J; Lindgren, F; Sjöström, M; Skagerberg, B; Wold, S | 1 |
| Couture, R; Jacques, L | 1 |
| Awaya, S; Kumazawa, T; Mizumura, K; Yokoyama, K | 1 |
| Chester, AH; Moncada, S; O'Neil, GS; Tadjkarimi, S; Yacoub, MH | 1 |
| Cohan, VL; Lichtenstein, LM; MacGlashan, DW; Proud, D; Warner, JA | 1 |
| Abraham, WM; Ahmed, A; Baugh, LE; Cortes, A; Farmer, SG; Harbeson, SL; Soler, M | 1 |
| Delashaw, JB; Duling, BR | 1 |
| Erdös, EG; Jackman, HL; Skidgel, RA | 1 |
| Gitter, BD; Howbert, JJ; Nixon, JA; Regoli, D; Rouissi, N; Waters, DC | 1 |
| Yasui, C | 1 |
| Hall, JM; Morton, IK | 1 |
| Jones, AJ; Keen, P; Ray, NJ | 1 |
| Asai, K; Funaki, C; Hayashi, T; Hidaka, H; Ishikawa, T; Kuzuya, F; Kuzuya, M; Naito, M | 1 |
| Coderre, TJ; Gonzales, R; Levine, JD; Sherbourne, CD | 1 |
| Bronner, C; Bueb, JL; Landry, Y; Mousli, M; Rouot, B | 1 |
| Benedito, S; Nielsen, PJ; Nyborg, NC; Prieto, D | 1 |
| Förster, S; Schrör, K; Woditsch, I | 1 |
| Andersson, RG; Lindgren, BR; Persson, K; Rosenqvist, U | 1 |
| Martinez, EJ; Seleznick, MJ | 1 |
| Amann, R; Donnerer, J; Lembeck, F | 1 |
| Drapeau, G; Jukic, D; Regoli, D; Rhaleb, NE; Rouissi, N | 1 |
| Jansen, I; Jensen, K; Pedersen-Bjergaard, U; Tuxen, C | 1 |
| Jukic, D; Nantel, F; Regoli, D; Rhaleb, NE; Rouissi, N | 1 |
| Katsumata, U; Sasaki, H; Sekizawa, K; Takishima, T; Ujiie, Y | 1 |
| Mandrek, K; Milenov, K | 1 |
| Claing, A; D'Orléans-Juste, P; Regoli, D; Télémaque, S; Warner, TD | 1 |
| Edwall, L; Gazelius, B; Olgart, L | 1 |
| Aoki, J; Inoue, K; Matsuda, K; Nagaya, K; Suzuki-Nishimura, T; Uchida, MK; Umeda, M | 1 |
| Christie, MI; Lewis, MJ | 1 |
| Kanai, Y; Misawa, M | 1 |
| Gustafsson, LE; Hedqvist, P; Persson, MG | 1 |
| Leek, BF; Maas, CL | 1 |
| Befus, D; Bienenstock, J; Denburg, JA; Fox, J; Shanahan, F | 1 |
| D'Orléans-Juste, P; Dion, S; Mizrahi, J; Regoli, D | 1 |
| Fujiwara, M; Muramatsu, I; Ueda, N | 3 |
| Lindberg, S; Mercke, U | 1 |
| Badikov, VI; Burchuladze, RA; Fedianina, NG; Gabuniia, AE; Kashmanov, SI | 1 |
| Amara, SG | 1 |
| Goncharova, VA | 1 |
| Becker, KL | 1 |
| Brain, SD; Williams, TJ | 1 |
| Devillier, P; Giroud, JP; Regoli, D; Renoux, M | 1 |
| Akopyan, TN; Arutunyan, AA; Arzumanyan, AM | 1 |
| Lew, WY; Longhurst, JC | 1 |
| Carretero, OA; Murray, RD; Salgado, HC; Scicli, AG | 1 |
| Hirota, Y; Inoki, R; Joh, S; Kotani, Y; Matsuura, H; Shibutani, T; Sugiyama, K | 1 |
| Paegelow, I; Werner, H | 1 |
| Altura, BM; Burton, RW; Gebrewold, A | 1 |
| Daniel, TO; Garovoy, MR; Gibbs, VC; Milfay, DF; Williams, LT | 1 |
| Bauer, V; Matusák, O | 1 |
| Inoki, R; Ohkubo, T; Shibata, M; Takahashi, H | 2 |
| McWade, D; Rangachari, PK | 1 |
| Abrams, GM; Recht, LD | 1 |
| Demarest, KT; Genovesi, S; Stein, RD; Weaver, LC | 1 |
| Garzón, J; Herz, A; Höllt, V; Sánchez-Blázquez, P | 1 |
| Kenny, AJ; Stephenson, SL | 2 |
| Goadsby, PJ; Macdonald, GJ | 1 |
| Beny, JL; Brunet, P; Huggel, H | 1 |
| Kumazawa, T; Mizumura, K; Sato, J | 1 |
| Beding, B; Ekman, R; Håkanson, R; Heilig, M; Sundler, F; Wahlestedt, C | 1 |
| Inoki, R; Shibutani, T; Yonehara, N | 1 |
| Regoli, D | 1 |
| Deblois, D; Marceau, F | 1 |
| Alheid, U; Förstermann, U; Frölich, JC; Haverich, A; Mügge, A | 1 |
| Bassett, JE; Dacey, RG; Takayasu, M | 1 |
| Henry, JL; Salter, MW | 1 |
| Couture, R; Dorais, J; Laneuville, O | 1 |
| Andrews, PL; Young, JZ | 1 |
| Brousseau, A; DeFelice, AF | 1 |
| Frilli, S; Geppetti, P; Maggi, CA; Manzini, S; Perretti, F | 1 |
| White, DM; Zimmermann, M | 1 |
| Cohen, RH; Perl, ER | 1 |
| Fisher, MC; Kimball, ES | 1 |
| Hirota, Y | 1 |
| Gamse, R; Lundberg, JM; Martling, CR; Saria, A; Theodorsson-Norheim, E; Yan, Z | 1 |
| Bény, JL; Brunet, PC | 2 |
| Hayashi, K; Ito, K; Murakami, T; Nakashima, T | 1 |
| Bény, JL; Brunet, PC; Van der Bent, V | 1 |
| Chipens, GI; Nikiforovich, GV; Saulitis, JB; Shenderovich, MD | 1 |
| Alving, K; Lacroix, JS; Lundberg, JM; Martling, CR; Matran, R | 1 |
| Bathon, JM; Krackow, K; Proud, D; Wigley, FM | 1 |
| Brunelli, G; Daffonchio, L; Hernandez, A; Omini, C | 2 |
| De Benedetti, L; Geppetti, P; Maggi, CA; Manzini, S; Perretti, F; Pradelles, P | 1 |
| Cox, HM; Cuthbert, AW | 1 |
| Ehlers, MR; Riordan, JF | 1 |
| Bekemeier, H; Sänze, JU | 1 |
| Okamura, T; Toda, N | 1 |
| Cecconi, R; Geppetti, P; Giuliani, S; Maggi, CA; Meli, A; Patacchini, R; Santicioli, P | 1 |
| Lopez-Belmonte, J; Rees, DD; Whittle, BJ | 1 |
| Antsans, IuE; Chipens, GI; Porunkevich, EA; Ratkevich, MP | 1 |
| Leah, JD; White, DM; Zimmermann, M | 1 |
| Berkenboom, G; Degre, S; Fang, ZY; Fontaine, J; Unger, P | 1 |
| Förstermann, U; Kuhn, M | 1 |
| D'Orléans-Juste, P; Dion, S; Drapeau, G; Escher, E; Mizrahi, J; Regoli, D | 1 |
| Garzón, J; Herz, A; Höllt, V; Schulz, R | 1 |
| Erdös, EG; Johnson, AR | 1 |
| Garcia Leme, J; Hamamura, L | 1 |
| Bertaccini, G; Impicciatore, M | 1 |
| Konishi, S; Otsuka, M | 1 |
| Singh, I | 2 |
| Diniz, CR; Hial, V; Pittella, JE; Tafuri, WL | 1 |
| Fischer, G; Lembeck, F | 1 |
| Mönkemeier, D; Wiechell, H; Zetler, G | 1 |
| Juan, H; Lembeck, F | 2 |
| Bertaccini, G; Cei, JM; Erspamer, V | 1 |
| Lewis, GP; Reit, E | 1 |
| Werle, E | 1 |
| Grassi, M; Grossi, F | 2 |
| Sjöstrand, NO; Swedin, G | 1 |
| Falconieri Erspamer, G; Negri, L; Piccinelli, D | 1 |
| Limacher, JJ; Phillis, JW | 2 |
| Hori, S | 1 |
| Antopol, W; Chryssanthou, C | 1 |
| Bynke, G; Håkanson, R; Wahlestedt, C | 1 |
| Hamprecht, B | 1 |
| Iven, H; Pursche, R; Zetler, G | 1 |
| Butler, JM; Hammond, BR | 1 |
| Alexander, RW; Gimbrone, MA; Gunther, S | 1 |
| Hack, U; Juan, H; Lembeck, F; Seewann, S | 1 |
| Snyder, SH | 1 |
| Chernukh, AM; Gomazkov, OA; Oeme, P | 1 |
| Bertaccini, G; Coruzzi, G | 1 |
| Antunes-Rodrigues, J; Caldo, H; Coelho, HL; Greene, LJ; Martins de Camargo, AC; Martins, AR; Moreira, AC | 1 |
| Clark, KE; Mills, EG; Seeds, AE; Stys, SJ | 1 |
| Lembeck, F | 1 |
| Barabé, J; Couture, R; Gaudreau, P; Marceau, F; Regoli, D | 1 |
| Erdös, EG; Mutt, V; Said, SI | 1 |
| Iven, H; Zetler, G | 1 |
| Malik, KU; Nasjletti, A; Susić, H | 1 |
| Abdel-Hakim, AM; Elhilali, M; Rioux, F | 1 |
| Helle, KB; Jørgensen, G; Knudsen, R; Serck-Hassen, G | 1 |
| Terenius, L | 1 |
| Baertschi, AJ; Dreifuss, JJ; Zingg, HH | 1 |
| Knap, M; Marceau, F; Regoli, D | 1 |
| Chang, JK; Pang, PK; Schimizu, M; Tenner, TE; Yang, CM | 1 |
| Inoki, R; Kotani, Y; Kudo, T; Oka, M; Yonehara, N | 1 |
| Said, SI | 2 |
| Baroody, RA; Bito, LZ; Nichols, RR | 1 |
| Luttinger, D; Nemeroff, CB; Prange, AJ | 1 |
| Butler, JM; Cole, DF; Ohara, K; Zhang, SQ | 1 |
| Eränkö, L; Tervo, K; Tervo, T | 1 |
| Growcott, JW; Tarpey, AV | 1 |
| Fujiwara, M; Hayashi, H; Muramatsu, I; Ueda, N | 1 |
| Abrams, GM; Recht, L | 1 |
| Chelala, CA; Huidobro-Toro, JP; Musacchio, JM | 1 |
| Baccaglini, PI; Hogan, PG | 1 |
| Nakajima, K | 1 |
| Burleigh, DE | 1 |
| Barabé, J; Fournier, A; Kérouac, R; Rioux, F; St-Pierre, S | 1 |
| Ishii, S; Ogura, Y; Yokosawa, H | 1 |
| Baertschi, AJ; Barja, F; Mathison, R; Stoppini, L | 1 |
| Bynke, G; Håkanson, R; Hörig, J; Leander, S | 1 |
| Abdel-Hakim, A; Abdel-Rahman, M; Elhilali, M; Galeano, C; Hassouna, M; Rioux, F; St-Pierre, S | 1 |
| Mouri, T; Murakami, O; Yoshinaga, K | 1 |
| Gintzler, AR; Hyde, D | 1 |
| Angus, JA; Campbell, GR; Cocks, TM; Manderson, JA | 1 |
| Lembeck, F; Lundberg, JM; Saria, A; Skofitsch, G | 1 |
| Furchgott, RF | 1 |
| Baertschi, J; Barja, F; Mathison, R; Stoppini, L | 1 |
| Foreman, JC; Piotrowski, W | 1 |
| Eriksson, M; Gerdin, B; Saldeen, T | 1 |
| Eriksson, M; Saldeen, K; Saldeen, T; Strandberg, K; Wallin, R | 1 |
| Hernandez, DE; Luttinger, D; Nemeroff, CB; Prange, AJ | 1 |
| Larbig, W; Schoenenberger, GA | 1 |
| Suzuki, Y; Tomita, Y | 1 |
| Boyd, RK; Tang, XJ; Thibault, P | 1 |
| Lewis, MJ; Siney, L | 1 |
| Barnes, PJ; Belvisi, MG; Miura, M | 1 |
| Couture, R; Lopes, P; Regoli, D | 1 |
| McDonald, DM; Sulakvelidze, I | 1 |
| Akita, H; Hirata, K; Inoue, N; Yokoyama, M | 1 |
| Ichinose, M; Igarashi, A; Inoue, H; Miura, M; Nakajima, N; Shirato, K; Takahashi, T; Takishima, T; Yamauchi, H | 1 |
| Bowie, D; Feltz, P; Schlichter, R | 1 |
| Mo, N; Wallis, DI; Watson, A | 1 |
| Bény, JL; Chabaud, F; Danna, M | 1 |
| Alford, C; Bunn, PA; Chan, D; Gera, L; Jewett, P; Mochzuki, T; Stewart, J; Tagawa, M; Tolley, R; Yanaihara, N | 1 |
| Garrison, EA; Kadowitz, PJ; Santiago, JA | 1 |
| Proud, D; Subauste, MC; Ward, PE | 1 |
| Brenner, T; Levi-Schaffer, F; Shalit, M; Soffer, D | 1 |
| Cheng, DY; DeWitt, BJ; Kadowitz, PJ; McMahon, TJ | 1 |
| Armour, JA; Huang, MH; Wolf, SG | 1 |
| Bund, SJ; Heagerty, AM; Oldham, AA | 1 |
| Dray, A; Naeem, S; Patel, IA; Urban, L | 1 |
| Campbell, WB; Vasko, MR; Waite, KJ | 1 |
| Abe, T; Kaito, N; Nakajima, M; Onoue, H; Tokudome, S; Tomii, M | 1 |
| Mäkinen, KK; Mäkinen, PL; Syed, SA | 2 |
| Brain, SD; Euzger, H; Wilsoncroft, P | 1 |
| Hull, AD; Pearce, WJ; White, CR | 1 |
| Boyd, RK; Tang, XJ | 1 |
| Armour, JA; Huang, MH; Pelleg, A; Sylvén, C | 1 |
| Gotoh, H; Hikawa, N; Hori, H; Kano, M; Kawakami, T; Takenaka, T | 1 |
| Bowden, JJ; McDonald, DM; Sulakvelidze, I | 1 |
| Bian, RL; Imai, Y; Inoki, R; Takiuchi, S; Tang, FD; Yonehara, N | 1 |
| Anning, P; Evans, H; Grocott-Mason, R; Lewis, MJ; Shah, AM | 1 |
| Tesfamariam, B | 1 |
| Woodhead, CJ | 1 |
| Bertrand, C; Chan, B; Geppetti, P; Nadel, JA; Ricciardolo, FL; Yamawaki, I | 1 |
| Bowles, W; Garry, MG; Hargreaves, KM; Jackson, DL; Roszkowski, MT; Swift, JQ | 1 |
| Botella, A; Bueno, L; Delvaux, M; Fioramonti, J; Frexinos, J | 1 |
| Hingtgen, CM; Vasko, MR | 2 |
| Brett, SE; Chowienczyk, PJ; Cockcroft, JR; Ritter, JM | 1 |
| Englberger, W; Friderichs, E; Reimann, W; Selve, N; Wilffert, B | 1 |
| Hoyle, CH | 1 |
| Ansari, KU | 1 |
| Frendl, G; Reenstra, WR; Stahl, GL | 1 |
| Scheinberg, DA; Wellner, D; Xu, Y | 1 |
| Chang, LC; Kuo, SC; Raung, SL; Wang, JP | 1 |
| Inoki, R; Katori, M; Oh-ishi, S; Saito, K; Yonehara, N | 1 |
| Brain, SD; Newbold, P | 1 |
| Giuliani, S; Lecci, A; Maggi, CA; Meini, S | 1 |
| Lee, H; Lubman, DM | 1 |
| Diekmann, O; Tschesche, H | 1 |
| Damas, J | 1 |
| Logsdon, CD; Simeone, DM; Williams, JA; Yule, DI | 1 |
| Lloyd, GS; Turner, AJ | 1 |
| Advenier, C; Biyah, K | 1 |
| de las Alas, MM; Doria, M; Gaginella, TS; Kachur, JF; Keshavarzian, A; Sundaresan, R; Walsh, R | 1 |
| Carraway, RE; Cochrane, DE; Feldberg, RS; Miller, LA | 2 |
| Cook, DA; Tsuji, T | 1 |
| Cioncolini, F; Figini, M; Geppetti, P; Javdan, P | 1 |
| Arakawa, H; Maeda, S; Morikawa, A; Tokuyama, K | 1 |
| Abe, T; Akiyama, M; Kaito, N; Onoue, H; Tokudome, S; Tomii, M | 1 |
| Inoue, H; Koshihara, Y; Nagata, N | 1 |
| Brain, SD; Cambridge, H | 1 |
| Levi-Schaffer, F; Slavin, S; Vourka-Karussis, U | 1 |
| Abe, T; Kaito, N; Nagashima, H; Nakamura, N; Onoue, H; Tashibu, K; Tokudome, S | 1 |
| Barnes, PJ; Chung, KF; Sakamoto, T | 1 |
| Couture, R; Pham, TM | 1 |
| Jain, B; Leise, KL; Robbins, RA; Rubinstein, I; Sisson, JH | 1 |
| Advenier, C; Molimard, M | 1 |
| Kaya, H; Ohkubo, T; Shibata, M; Takahashi, H; Yamada, Y | 1 |
| Advenier, C; Emonds-Alt, X; Qian, Y | 1 |
| Alhenc-Gelas, F; Jaspard, E; Wei, L | 1 |
| Fan, TP; Hori, Y; Hu, DE | 1 |
| Ichishima, E; Tanaka, T | 1 |
| Giuliani, S; Lecci, A; Lippe, IT; Maggi, CA; Santicioli, P | 1 |
| Coy, DH; Gu, ZF; Jensen, RT; Pradhan, TK; Rossowski, WJ | 1 |
| Marriott, DR; Wilkin, GP | 1 |
| Bertrand, C; Geppetti, P; Nadel, JA; Yamawaki, I | 1 |
| Imai, Y; Inoki, R; Takiuchi, S; Tang, FD; Yonehara, N | 1 |
| Hall, JM; Mitchell, D; Morton, IK | 1 |
| Ando, R; Kawamura, S; Kume, H; Sakurada, T; Yonezawa, A | 1 |
| Hess, HJ; Kanai, Y; Lowe, JA; Nagahisa, A; Suga, O; Taniguchi, K; Tsuchiya, M | 1 |
| Kopp, UC; Smith, LA | 1 |
| Gentle, MJ; Hunter, LN | 1 |
| Advenier, C; Martin, CA | 1 |
| Land, T; Langel, U; Ogren, SO; Pramanik, A | 1 |
| Ebihara, A; Fujimura, A; Shiga, T; Sunaga, K | 1 |
| Emanueli, C; Figini, M; Geppetti, P; Javdan, P | 1 |
| Barber, LA; Vasko, MR | 1 |
| Patra, PB; Westfall, DP | 1 |
| Chadwick, IG; Jackson, PR; Kraskiewicz, M; Ramsay, LE; Yeo, WW | 1 |
| Baskin, SI; Lempka, JC; Nealley, EW | 1 |
| Baumgarten, CR; Kleine-Tebbe, J; Kunkel, G; Witzel, A | 1 |
| Gecse, A; Kis, B; Mezei, Z; Telegdy, G | 1 |
| Beckey, VE; Francis, M; Goodfellow, VS; Jones, S; Srivastava, VP; Whalley, ET; Zuzack, JS | 1 |
| Ma, RC; Szurszewski, JH | 1 |
| Armour, JA; Horackova, M; Huang, MH; Negoescu, RM; Wolf, S | 1 |
| Seybold, VS; Stucky, CL; Thayer, SA | 1 |
| Arakawa, M; Goto, F; Katori, M; Majima, M; Nagai, K | 1 |
| Amerini, S; Ledda, F; Maggi, CA; Parenti, A; Zawieja, D; Ziche, M | 1 |
| Nava, E; Salazar, FJ; Wiklund, NP | 1 |
| Bourdon, V; Damas, J; Liégeois, JF; Simmons, WH | 1 |
| Fredberg, JJ; Heyder, J; Hubmayr, RD; Moller, W; Panettieri, RA; Planus, E; Shore, SA; Wang, N | 1 |
| Chen, YH; Kuo, SC; Wang, JP | 1 |
| Barrett, LT; May, SW; Moore, AB; O'Bryant, CL; Ogonowski, AA; Pollock, SH | 1 |
| Hore, SK; Kumar, D; Tandan, SK; Tripathi, HC | 1 |
| Atzori, L; Bannenberg, G; Congiu, L; Corriga, AM; Lundberg, JM; Moldèus, P; Ryrfeldt, A | 1 |
| Bjorling, DE; Franz, J; Saban, R | 1 |
| Gilabert, R; McNaughton, P | 1 |
| Ansel, J; Bunnett, N; Emanueli, C; Figini, M; Geppetti, P; Gerard, C; Grady, EF; Kirkwood, K; Payan, DG | 1 |
| Bourdon, V; Damas, J; Liégeois, JF | 1 |
| D'Agostino, PA; Hancock, JR; Provost, LR | 1 |
| Trakranrungsie, N; Will, JA | 1 |
| Bjorling, DE; Saban, MR; Saban, R | 2 |
| Helyes, Z; Németh, J; Pintér, E; Szolcsányi, J | 1 |
| Kettenmann, H; Labrakakis, C; Möller, T; Patt, S; Weydt, P | 1 |
| Baker, AG; Houston, CT; Novotny, MV; Reilly, JP | 1 |
| Farley, DM; Kopp, UC; Smith, LA | 1 |
| Champion, HC; Kadowitz, PJ | 1 |
| Ansell, J; Bunnett, N; Emanueli, C; Figini, M; Geppetti, P; Gerard, C; Gerard, NP; Grady, EF; Lu, B; Payan, DG | 1 |
| Carrier, M; Dupuis, J; Mathieu, P; Pelletier, LC; Ryan, J | 1 |
| Gobeil, F; Nguyen-Le, XK; Nsa Allogho, S; Pheng, LH; Regoli, D | 1 |
| Böhm, SK; Bunnett, NW; Caughey, GH; Corvera, CU; Déry, O; Khitin, LM; McConalogue, K; Payan, DG | 1 |
| Cross, LJ; Ennis, M; Heaney, LG | 1 |
| Champion, HC; DeWitt, BJ; Giles, TD; Greenberg, SS; Kadowitz, PJ; Marrone, JR; McNamara, DB | 1 |
| Welton, ML | 1 |
| Andersson, RG; Lindström, EG | 1 |
| Calixto, JB; Cechinel Filho, V; de Campos, RO; Delle Monache, F; Pinheiro, TR; Pizzolatti, MG; Santos, AR; Vaz, ZR; Yunes, RA | 1 |
| Aalkjaer, C; Bjurholm, A; Hansen, ES; Lundgaard, A; Mulvany, MJ | 1 |
| Baumgarten, CR; Dokic, D; Kunkel, G; O'Connor, A; Schultz, KD | 1 |
| Brunz, JT; Miller, AJ; Percy, WH | 1 |
| Gauthier-Rein, KM; Rusch, NJ | 1 |
| Heppelmann, B; Pawlak, M | 1 |
| Katsuragi, T; Sato, C; Tamesue, S | 1 |
| Ens, W; Krutchinsky, AN; McComb, ME; Perreault, H; Standing, KG | 1 |
| Goodis, H; Saeki, K | 1 |
| Cunningham, DF; O'Connor, B | 1 |
| Bunnett, NW; Emanueli, C; Figini, M; Geppetti, P; Grady, EF; Madeddu, P; Parisi, D; Regoli, D | 1 |
| de Beer, WH; Lehmann, SM | 1 |
| Helyes, Z; Németh, J; Oroszi, G; Pintér, E; Szolcsányi, J; Thán, M | 1 |
| Carbini, LA; Gorelik, G; Scicli, AG | 1 |
| Calixto, JB; Campos, MM; Cechinel Filho, V; Mendes, GL; Santos, AR; Tratsk, KS; Yunes, RA | 1 |
| Katusic, ZS; O'Brien, T; Onoue, H; Smith, L; Stelter, A; Tsutsui, M | 1 |
| Cooper, A; Heagerty, AM | 1 |
| Dellsperger, KC; Gutterman, DD; Miller, FJ | 1 |
| Asztély, A; Ekström, J; Havel, G | 1 |
| Brain, SD; Towler, PK | 1 |
| Calixto, JB; Chakravarty, S; Creczynski-Pasa, TB; Kyle, DJ; Mavunkel, BJ; Saleh, TS; Vianna, RM | 1 |
| Blair, SJ; Chinthagada, M; Fareed, J; Hoppenstehdt, D; Kijowski, R | 1 |
| Böckmann, S; Mohrdieck, K; Paegelow, I | 1 |
| Baluk, P; Bunnett, NW; McDonald, DM; Murphy, TJ; Thurston, G | 1 |
| Ahlenius, S; Ericson, E | 1 |
| Ichinose, M | 1 |
| Averbeck, B; Ebersberger, A; Messlinger, K; Reeh, PW | 1 |
| Bueno, L; Fioramonti, J | 1 |
| Brain, SD; Brown, B; Hoult, JR; Pintér, E | 1 |
| Ahluwalia, A; Scotland, R; Vallance, P | 1 |
| Levi, R; Maruyama, R; Seyedi, N | 1 |
| Garry, MG; Geier, HE; Hargreaves, KM; Jackson, DL; Southam, M | 1 |
| Ferreira, SH; Tonussi, CR | 1 |
| de Hemptinne, A; Leybaert, L; Paemeleire, K | 1 |
| Minc, P; Szmidt, M | 1 |
| Bienenstock, J; Furuno, T; McKay, DM; Nakanishi, M; Suzuki, R; Teshima, R; Wolvers, D | 1 |
| Beny, J; Frieden, M; Sollini, M | 1 |
| Mikkelsen, EO; Simonsen, U; Tankó, LB | 1 |
| Calixto, JB; Cechinel-Filho, V; De Campos, RO; Miguel, OG; Santos, AR; Yunes, RA | 1 |
| Endoh, N; Ichinose, M; Mashito, Y; Miura, M; Shirato, K; Sugiura, H | 1 |
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| Ishii, K; Nakayama, K; Tanaka, Y; Uchida, H | 1 |
| Caldwell, RW; Ganapathy, V; Jin, L; Kaesemeyer, WH; Leibach, FH; Ogonowski, AA | 1 |
| Iida, Y; Katusic, ZS; O'Brien, T; Onoue, H; Smith, L; Tsutsui, M | 1 |
| Fenselau, C; Ho, YP | 1 |
| Boels, PJ; Deutsch, J; Gao, B; Haworth, SG | 2 |
| Inoue, M; Mishina, M; Ueda, H | 1 |
| Cicha, MZ; Farley, DM; Kopp, UC; Smith, LA | 1 |
| MacCarthy, PA; Shah, AM | 1 |
| Asti, C; Bertini, R; Brandolini, L; Caselli, GF; Chiusaroli, R; Intilangelo, A; Pellegrini, L; Ruggieri, V | 1 |
| Al-Rashed, S; Brain, SD; Cao, T; Gerard, N; Hoult, JR; Pintér, E | 1 |
| Bjorling, DE; Jerde, TJ; Nakada, SY; Saban, R; Steinberg, H | 1 |
| Ahluwalia, A; McLean, PG; Perretti, M | 1 |
| Axelsson, M; Conlon, JM; Jensen, J; Wang, T | 1 |
| Itoh, T; Kajikuri, J; Suzuki, Y; Suzumori, K | 1 |
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| Bergren, DR | 2 |
| Averbeck, B; Reeh, PW | 1 |
| Freedman, RR; Girgis, R; Mayes, MD | 1 |
| Furuya, K; Kawakami, Y; Takahashi, T; Yamaguchi, E | 1 |
| Amann, R; Peskar, BA; Schuligoi, R | 1 |
| Arnal, JF; Bayard, F; Castano, C; Darblade, B; Gourdy, P; Maupas, E; Michel, JB; Mugniot, A | 1 |
| Brandle, U; Geisler, HS; Glowatzki, E; Gründer, S; Osteroth, R; Paukert, M; Ruppersberg, JP | 1 |
| Echizen, H; Fukatsu, T; Hashiguchi, M; Itoh, T; Kariya, S; Nishimura, E; Odanaka, J; Ohtani, M; Okumura, H; Rikihisa, T; Takahashi, T; Uchino, K; Watanabe, K | 1 |
| Cabrini, DA; Calixto, JB; Campos, MM; Cardozo, AH; Rae, GA; Toro, JH | 1 |
| Ebersberger, A | 1 |
| Aalkjaer, C; Forman, A; Hansen, ES; Hansen, VB; Lundgaard, A; Skajaa, K | 1 |
| Higgins, RD; Keszler, M | 1 |
| Gillard, SE; Hammond, DL; Hurley, RW; Miller, RJ; Oh, SB; Tran, PB | 1 |
| Edwards, G; Félétou, M; Gardener, MJ; Glen, CD; Richards, GR; Vanhoutte, PM; Weston, AH | 1 |
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| Furue, M; Hirano, K; Kanaide, H; Nishimura, J; Ohnishi, Y | 1 |
| Carpenter, TC; Stenmark, KR | 1 |
| Byrne, B; Clive, S; Jodrell, DI; MacLellan, A; Robson, L; Smyth, JF; Webb, DJ; Young, A | 1 |
| Fox, KA; Helmy, A; Newby, DE; Webb, DJ; Witherow, FN | 1 |
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| Berkenboom, G; Crasset, V; Unger, P | 1 |
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| Hayashi, I; Kamijo, Y; Majima, M; Ohwada, T; Soma, K | 1 |
| Davie, AP; McMurray, JJ | 1 |
| Haraldsen, L; Nilsson, GE; Söderström-Lauritzsen, V | 1 |
| Deobagkar, DD; Kulkarni, GV | 1 |
| Armour, JA; Horackova, M; Thompson, GW | 1 |
| Bhalla, P; de Vries, R; Saxena, PR; Sharma, HS; van den Broek, RW; VanDenBrink, AM | 1 |
| Chan, KK; Covey, JM; Feng, WY | 1 |
| Cicha, MZ; Kopp, UC; Smith, LA | 2 |
| Assem, ES; Pearce, FL; Peh, KH; Wan, BY; Yue, SC | 1 |
| Clevenger, CM; DeSouza, CA; Greiner, JJ; Hoetzer, GL; Shapiro, LF; Smith, DT; Stauffer, BL | 1 |
| Bény, JL; Frieden, M; Sollini, M | 1 |
| Janas, J; Janas, RM; Socha, J; Warnawin, K | 1 |
| Ansai, T; Awano, S; Carson, JA; Takehara, T; Turner, AJ; Yu, W | 1 |
| Dawson, P; Fox, KA; Ludlam, CA; Newby, DE; Witherow, FN | 1 |
| Kaneyama, K; Miyamaru, M; Nishimura, M; Segami, N; Suzuki, T | 1 |
| Bény, JL; Marie, I | 1 |
| Burggraaf, J; Chia, S; Cohen, AF; Kemme, MJ; Kluft, C; Newby, DE; Schoemaker, RC; Webb, DJ | 1 |
| Herrmann, J; Lerman, A; Lerman, LO; Napoli, C; Rodriguez-Porcel, M; Sawamura, T | 1 |
| Angdin, M; Liska, J; Lundberg, JO; Malmström, RE; Settergren, G; Törnberg, DC; Weitzberg, E | 1 |
| Adler, JE; Resta, C; Skoff, AM; Swamydas, M | 1 |
| Inoue, M; Kawashima, T; Kishioka, S; Maeda, T; Matsumoto, M; Rashid, MH; Ueda, H | 1 |
| Cummings, J; Haslett, C; Jodrell, D; MacKinnon, AC; Sethi, T; Tufail-Hanif, U; Waters, CM | 1 |
| Davies, C; Harrison, NK; Hilldrup, S; Hope-Gill, BD; Newton, RP | 1 |
| Barbara, G; Blennerhassett, PA; Bunnett, NW; Collins, SM; Corinaldesi, R; Cremon, C; De Giorgio, R; Gerard, C; Gerard, N; Grady, EF; Stanghellini, V | 1 |
| PERNOW, B; ROCHA E SILVA, M | 1 |
| ZETLER, G | 1 |
| CLEUGH, J; GADDUM, JH; HOLTON, P; LEACH, E | 1 |
| BHOOLA, KD; COLLIER, HO; SCHACHTER, M; SHORLEY, PG | 1 |
| BISSET, GW; LEWIS, GP | 1 |
| SMITH, CM; WALASZEK, EJ | 1 |
| MICHAUD, J | 1 |
| LOEFSTROEM, B; PERNOW, B; WAHREN, J | 1 |
| Boileau, G; Carpentier, M; DesGroseillers, L; Marcinkiewicz, M | 1 |
| Hirooka, Y; Inokuchi, K; Ito, K; Kimura, Y; Kishi, T; Sakai, K; Shimokawa, H; Takeshita, A | 1 |
| Cuttle, G; Dovichi, SS; Nicolau, M | 1 |
| Armour, JA; Chen, RP; Waldmann, M | 1 |
| Avery, PS; Haywood, L; McWilliams, DF; Seegers, HC; Walsh, DA | 1 |
| Brooks, DP; Edwards, RM; Pullen, MA; Sulpizio, AC | 1 |
| Chuaychoo, B; Kollarik, M; Lee, MG; Myers, AC; Undem, BJ; Weinreich, D | 1 |
| Hoteling, AJ; Owens, KG | 1 |
| Lai, YL; Lu, FJ; Wu, LL | 1 |
| Bai, N; Laher, I; Min, A; Moien-Afshari, F; Washio, H | 1 |
| Liddle, RA; Nathan, JD | 1 |
| Graham, RM; Husain, A; Liu, K; Naqvi, N | 1 |
| Inoue, A; Kawamoto, M; Nakata, Y; Oshita, K; Tang, HB; Yuge, O | 1 |
| Hirate, K; Inoue, A; Nakata, Y; Oshita, K; Tang, HB | 1 |
| Amine, SA; El-Hashim, AZ | 1 |
| Campbell, WB; Edwards, G; Falck, JR; Félétou, M; Vanhoutte, PM; Weston, AH | 1 |
| Harris, WA; Reilly, PT; Whitten, WB | 1 |
| Danoff, JV; Gerber, LH; Phillips, TM; Shah, JP | 1 |
| Canning, BJ; Mazzone, SB; Mori, N | 1 |
| Guy, J; Murray, KK; Musyimi, HK; Narcisse, DA; Soper, SA | 1 |
| Fraser, MO; Pezzone, MA; Ustinova, EE | 1 |
| Berkout, VD | 1 |
| Hide, I; Inoue, A; Iwasa, M; Nakata, Y; Tang, HB | 1 |
| Hosogi, M; Ikoma, A; Miyachi, Y; Schmelz, M | 1 |
| Gutkin, DW; Pezzone, MA; Ustinova, EE | 1 |
| Fröde, TS; Montanher, AB; Schenkel, EP; Zucolotto, SM | 1 |
| Nakata, Y; Tang, HB | 1 |
| Fujimura, K; Kaneyama, K; Nagao, T; Sato, J; Segami, N; Yoshimura, H | 1 |
| Rubinstein, I | 1 |
| Jesse, CR; Nogueira, CW; Pinto, LG; Rocha, JB; Savegnago, L; Zeni, G | 1 |
| Evans, EH; Handy, R; Harrington, C; Jones, P; Marshall, P; Patel, P | 1 |
| Dolly, JO; Lawrence, G; Meng, J; Wang, J | 1 |
| Fröde, TS; Goulart, S; Lang, KL; Liz, R; Moritz, MI; Schenkel, EP | 1 |
| Buclin, T; Grouzmann, E | 1 |
| Adam, A; Brown, NJ; Byrd, JB; Gainer, JV; Nadeau, J; Sile, S; Touzin, K; Yu, C | 1 |
| Bailey, SR; Berhane, Y; Elliott, J; Putignano, C | 1 |
| Belch, JJ; Dias, MP; Khan, F; McLeod, GA; Newton, DJ | 1 |
| Desouza, CA; Greiner, JJ; Stauffer, BL; Van Guilder, GP | 1 |
| Kang, H; Lourette, NM; Pasa-Tolić, L; Robinson, EW; Smith, RD; Tolmachev, AV; Wu, S | 1 |
| Jesse, CR; Nogueira, CW; Savegnago, L | 1 |
| Antunes, E; Camargo, EA; de Nucci, G; Ferreira, T; Landucci, EC; Ribela, MT | 1 |
| Leung, SW; Man, RY; Ng, KF; Vanhoutte, PM | 1 |
| Barbosa, AL; Moraes, MO; Oliveira, GJ; Pinheiro, CA; Ribeiro, RA; Souza, MH; Vale, ML | 1 |
| Collin, OL; Cook, SL; Jackson, GP | 1 |
| Shvartsburg, AA; Smith, RD; Tang, K | 1 |
| Biavatti, MW; Bürger, C; Busnardo, TC; Claudino, VD; Dalmarco, EM; de Souza, MM; Fröde, TS; Mora, TC; Padoani, C | 1 |
| DuBuske, L; Gawlik, R | 1 |
| Beckett, T; Hersh, LB; Klein, RL; Liu, Y; Murphy, MP; Studzinski, C | 1 |
| Douglas, DJ; Terrier, P | 1 |
| Baker, SJ; Bianchi, BR; Faltynek, CR; Gauvin, DM; Han, P; Honore, P; Joshi, SK; Koenig, JR; Kort, ME; Kym, PR; Lewis, GR; Mikusa, JP; Neelands, TR; Perner, RJ; Puttfarcken, PS; Reilly, RM | 1 |
| Back, W; de Grauw, JC; L'ami, JJ; van Dierendonck, M; van Loon, JP; van Weeren, PR | 1 |
| Birklein, F; Fuchs, D; Reeh, PW; Sauer, SK | 1 |
| Gao, XP; Rubinstein, I | 1 |
| Arms, L; Vizzard, MA | 1 |
| Byrd, JS; Elsayed, R; Marshall, GD; Minor, DS | 1 |
| Emala, CW; Masaki, E; Mizuta, F; Mizuta, K; Panettieri, RA; Xu, D | 1 |
| Jia, MM; Li, XJ; Li, YS; Liu, M; Tang, HB; Wang, JX | 1 |
| Bodenhausen, G; Delsuc, MA; Rolando, C; van Agthoven, MA | 1 |
| Assreuy, AM; Coelho-de-Souza, AN; Leal-Cardoso, JH; Ponte, EL; Rocha, MV; Soares, PM; Sousa, PL | 1 |
| Lacetera, N; Macis, M; Slonim, R | 1 |
| Jia, MM; Li, XJ; Li, YS; Mao, XQ; Tang, HB; Yang, YL | 1 |
| Chen, RW; Wang, Y; Wang, YB; Yang, B; Zhang, HL; Zhou, L | 1 |
| Billings, FT; Brown, NJ; Devin, JK; Nian, H; Pretorius, M; Yu, C | 1 |
| Anderson, TM; Chase, K; Curtice, KJ; Garcia, AJ; Olivera, BM; Raghuraman, S; Ramirez, JM; Teichert, RW; Twede, VD | 1 |
| Gerdle, B; Kristiansen, J; Larsson, B; Saltin, B; Sjøgaard, G; Søgaard, K | 1 |
| Arlinghaus, HF; Dreisewerd, K; Körsgen, M; Pelster, A | 1 |
| Ahlijanian, MK; Graef, JD; Herrington, J; Hoque, N; Kiss, L; Newberry, K; Wang, S | 1 |
| Hamamura, K; Hirai, T; Kodama, D; Kondo, H; Togari, A | 1 |
| Arisi, I; Brandi, R; Bruni, B; Calissano, P; Cattaneo, A; Ciotti, MT; D'Onofrio, M; Florenzano, F; Malerba, F; Petrella, C; Petrocchi Passeri, P; Possenti, R; Severini, C | 1 |
| Aagaard, L; Andersen, MF; Buchwald, CV; Rasmussen, ER; Scott, SI | 1 |
| Beaudry, F; Guillot, M; Martel-Pelletier, J; Moreau, M; Otis, C; Pelletier, JP; Troncy, E | 1 |
| Ali, H; Alkanfari, I; Gupta, K; Jahan, T | 1 |
| Chowdhury, YS; Kostis, JB; Kostis, WJ; Shetty, M | 1 |
| Chua, I; Kennedy, MA; Liau, Y; Maggo, S | 1 |
| Djordjevic, SP; Jarocki, VM; Padula, MP; Raymond, BBA; Tacchi, JL | 1 |
| Bayer, M; Engl, C; König, S; Schreiber, U | 1 |
| Barbato, E; Bellis, A; Di Gioia, G; Mauro, C; Morisco, C; Sorriento, D; Trimarco, B | 1 |
| Al-Ahmad, AJ; Karamyan, VT; Pervaiz, I | 1 |
| Karamyan, VT | 1 |
| Bayer, M; Birklein, F; Engl, C; Escolano-Lozano, F; König, S; Rebhorn, C; Rittner, H | 1 |
39 review(s) available for substance p and bradykinin
| Article | Year |
|---|---|
Peptide neurotransmitters.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Bradykinin; Brain; Brain Chemistry; Endorphins; Enkephalins; Neurotensin; Neurotransmitter Agents; Peptides; Receptors, Opioid; Substance P; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1979 |
Roles of peptides in central transmission: substance P, bradykinin and B-endorphin.
Topics: Animals; Anura; beta-Endorphin; Bradykinin; Cats; Central Nervous System; Endorphins; Pain; Peptides; Rats; Spinal Cord; Substance P; Synaptic Transmission; Trigeminal Nuclei | 1979 |
Pharmacology of colonic muscle.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Angiotensin II; Antidiarrheals; Atropine; Bradykinin; Cathartics; Cholecystokinin; Colon; Electric Stimulation; Gastrointestinal Motility; Histamine; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prostaglandins; Serotonin; Substance P | 1975 |
[Kinins and peripheral circulation].
Topics: Animals; Blood Circulation; Bradykinin; Capillary Permeability; Dogs; Heart Rate; Humans; Kallidin; Kinins; Microcirculation; Prostaglandins E; Substance P | 1978 |
[Site of action of analgesics: the peripheral site of action of these drugs].
Topics: Analgesics; Animals; Aspirin; Bradykinin; Endorphins; Feedback; Humans; Narcotics; Neurons, Afferent; Neurotransmitter Agents; Nociceptors; Substance P | 1990 |
Substance P, cytokines, and arthritis.
Topics: Animals; Arthritis; Biological Factors; Bradykinin; Cytokines; Histamine; Humans; Interleukin-1; Interleukin-6; Substance P; Tumor Necrosis Factor-alpha | 1990 |
Respiratory tract side effects of angiotensin converting enzyme inhibitors: current knowledge.
Topics: Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Cough; Humans; Nasal Obstruction; Receptors, Bradykinin; Receptors, Neurotransmitter; Substance P | 1991 |
Peptide diversity from exon choice: RNA processing regulation in the neuroendocrine system.
Topics: Base Sequence; Bradykinin; Calcitonin; Calcitonin Gene-Related Peptide; Gene Expression Regulation; Nerve Tissue Proteins; Neurosecretory Systems; Peptides; RNA Processing, Post-Transcriptional; RNA Splicing; RNA, Messenger; Substance P | 1985 |
[Vasoactive peptides of the lungs].
Topics: Animals; APUD Cells; Bombesin; Bradykinin; Humans; Lung; Lysine Carboxypeptidase; Oligopeptides; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Substance P; Vasoactive Intestinal Peptide | 1985 |
Neuropeptides and their role in nociception and analgesia.
Topics: Animals; Bombesin; Bradykinin; Calcitonin; Central Nervous System; Cholecystokinin; Endorphins; Neurons, Afferent; Neuropeptides; Neurotensin; Pain; Somatostatin; Substance P; Vasopressins | 1986 |
Angiotensin-converting enzyme: new concepts concerning its biological role.
Topics: Amino Acid Sequence; Angiotensins; Animals; Bradykinin; Gonadotropin-Releasing Hormone; Humans; Molecular Sequence Data; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Substance P | 1989 |
[Tissue hormones. A review].
Topics: Acetylcholine; Amines; Aminobutyrates; Angiotensin II; Animals; Bradykinin; Cholecystokinin; Dopamine; Epinephrine; Gastrins; Gastrointestinal Hormones; Histamine; Hormones; Kallidin; Kallikreins; Norepinephrine; Peptides; Prostaglandins; Renin; Secretin; Serotonin; Substance P; Tryptophan; Vasopressins | 1968 |
[Humoral factors and motility of the intestine. I. Kinino-hormones].
Topics: Angiotensin II; Animals; Bradykinin; Cholecystokinin; Gastrointestinal Hormones; Gastrointestinal Motility; Humans; Kallidin; Kinins; Peptides; Substance P | 1967 |
[Mechanics of actions of analgesics--especially on peripheral actions].
Topics: Acetylcholine; Analgesics; Animals; Bradykinin; Catecholamines; Chemoreceptor Cells; Drug Synergism; Histamine; Humans; Morphine; Pain; Peptide Hydrolases; Peripheral Nerves; Prostaglandins; Sensory Receptor Cells; Serotonin; Substance P | 1973 |
[Vasoactive polypeptide receptors].
Topics: Angiotensins; Animals; Blood Vessels; Bradykinin; Dogs; Guinea Pigs; Rabbits; Rats; Receptors, Cell Surface; Substance P | 1980 |
Biochemical mediators in pain.
Topics: Antidepressive Agents; Bradykinin; Endorphins; Histamine; Humans; Nociceptors; Pain; Prostaglandins; Serotonin; Substance P | 1981 |
Metabolic functions of the pulmonary circulation.
Topics: Angiotensins; Animals; Bradykinin; Endothelium; Epinephrine; Histamine; Humans; Lung; Neurotransmitter Agents; Norepinephrine; Prostaglandins; Pulmonary Circulation; Rabbits; Serotonin; Substance P; Vasoactive Intestinal Peptide; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 1982 |
Pulmonary metabolism of prostaglandins and vasoactive peptides.
Topics: Angiotensin I; Arachidonic Acids; Blood Vessels; Bradykinin; Lung; Peptides; Prostaglandin Antagonists; Prostaglandins; Substance P; Vasoactive Intestinal Peptide | 1982 |
Ocular neuropeptides.
Topics: Animals; Anterior Chamber; Bradykinin; Capsaicin; Enkephalins; Eye; Humans; Nerve Fibers; Neurotensin; Ocular Physiological Phenomena; Peptides; Pupil; Retina; Somatostatin; Substance P; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1982 |
Neuropeptides and their role in pain and analgesia.
Topics: Analgesia; Angiotensin II; Bombesin; Bradykinin; Cholecystokinin; Endorphins; Humans; Nerve Tissue Proteins; Neurotensin; Oligopeptides; Pain; Somatostatin; Substance P; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide; Vasopressins | 1982 |
[Blood pressure regulation and shock].
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Endorphins; Hypertension; Nerve Tissue Proteins; Neurotensin; Rats; Rats, Inbred Strains; Shock; Substance P; Vasopressins | 1983 |
The role of endothelium in the responses of vascular smooth muscle to drugs.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Catechols; Endothelium; Histamine; Hydroquinones; Hypoxia; Masoprocol; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Prostaglandins; Quinacrine; Serotonin; Substance P; Thrombin | 1984 |
Neuropeptides in nasal mucosa.
Topics: Bradykinin; Calcitonin Gene-Related Peptide; Cytokines; Eicosanoids; Histamine H1 Antagonists; Humans; Nasal Mucosa; Nasal Polyps; Neurokinin A; Neuropeptide Y; Platelet Activating Factor; Receptors, Calcitonin Gene-Related Peptide; Rhinitis; Substance P; Vasoactive Intestinal Peptide | 1994 |
Pharmacology of peripheral neuropeptide and inflammatory mediator release.
Topics: Bradykinin; Calcitonin Gene-Related Peptide; Dental Pulp; Dinoprostone; Humans; Inflammation Mediators; Leukotriene B4; Microdialysis; Neuropeptides; Nociceptors; Pulpitis; Substance P; Toothache | 1994 |
Non-adrenergic, non-cholinergic control of the urinary bladder.
Topics: Adenosine Triphosphate; Animals; Bombesin; Bradykinin; Calcitonin Gene-Related Peptide; gamma-Aminobutyric Acid; Humans; Muscle, Smooth; Neuromuscular Junction; Neuropeptide Y; Prostaglandins; Somatostatin; Substance P; Synaptic Transmission; Urinary Bladder; Vasoactive Intestinal Peptide | 1994 |
ACE inhibitor induced cough.
Topics: Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Cough; Humans; Prostaglandins; Substance P | 1994 |
Human colonic microvascular endothelial cells is a model of inflammatory bowel disease.
Topics: Bradykinin; Colon; Endothelial Growth Factors; Endothelium, Vascular; Humans; Inflammatory Bowel Diseases; Microcirculation; Models, Biological; Substance P | 1997 |
[Airway autonomic nervous system dysfunction and asthma].
Topics: Acetylcholine; Animals; Asthma; Autonomic Nervous System Diseases; Bradykinin; Bronchi; Cholinergic Fibers; Humans; Nitric Oxide; Substance P; Sympathetic Nervous System | 1999 |
Effects of inflammatory mediators on gut sensitivity.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcitonin Gene-Related Peptide; Colonic Diseases, Functional; Humans; Hyperalgesia; Inflammation Mediators; Intestines; Serotonin; Substance P | 1999 |
[Cough, bronchoconstriction and bronchial hyperreactivity in relation to treatment with angiotensin-converting enzyme].
Topics: Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Bronchial Hyperreactivity; Bronchial Spasm; Cough; Histamine; Humans; Prostaglandins; Substance P | 1999 |
Physiology of meningeal innervation: aspects and consequences of chemosensitivity of meningeal nociceptors.
Topics: Afferent Pathways; Animals; Bradykinin; Calcitonin Gene-Related Peptide; Dinoprostone; Disease Models, Animal; Headache; Humans; Meninges; Neurokinin A; Neuropeptides; Nociceptors; Prostaglandins; Substance P | 2001 |
Neurogenic inflammation and pancreatitis.
Topics: Bradykinin; Humans; Ion Channels; Neurogenic Inflammation; Neurons, Afferent; Pancreatitis; Receptors, Drug; Substance P; TRPV Cation Channels | 2004 |
Neuropeptides in lower urinary tract function.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Endothelins; Humans; Neural Pathways; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Neuropeptide; Reflex; Signal Transduction; Substance P; Tachykinins; Urinary Tract; Urination; Urologic Diseases; Vasoactive Intestinal Peptide | 2011 |
Towards analytically useful two-dimensional Fourier transform ion cyclotron resonance mass spectrometry.
Topics: Angiotensin I; Animals; Bradykinin; Computers; Cyclotrons; Electronics; Fourier Analysis; Humans; Ions; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metabolomics; Models, Statistical; Peptides; Proteins; Proteomics; Reproducibility of Results; Substance P; Tandem Mass Spectrometry | 2013 |
Dipeptidyl Peptidase-4 Inhibitor Induced Angioedema - An Overlooked Adverse Drug Reaction?
Topics: Angioedema; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Capillary Permeability; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Drug Interactions; Genetic Predisposition to Disease; Humans; Prognosis; Proteolysis; Risk Factors; Substance P; Vasodilation | 2018 |
ACE Inhibitor-Induced Angioedema: a Review.
Topics: Adrenal Cortex Hormones; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Capillary Permeability; Combined Modality Therapy; Epinephrine; Female; Histamine Antagonists; Humans; Hypertension; Intubation, Intratracheal; Risk Factors; Substance P; Vasodilation | 2018 |
Pharmacogenetics of angiotensin-converting enzyme inhibitor-induced angioedema.
Topics: Angioedema; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Genome-Wide Association Study; Humans; Pharmacogenetics; Polymorphism, Genetic; Prevalence; Substance P | 2019 |
The Rationale of Neprilysin Inhibition in Prevention of Myocardial Ischemia-Reperfusion Injury during ST-Elevation Myocardial Infarction.
Topics: Adrenomedullin; Aminobutyrates; Angiotensin II; Animals; Apelin; Atrial Natriuretic Factor; Biphenyl Compounds; Bradykinin; Cardiotonic Agents; Drug Combinations; Gene Expression Regulation; Humans; Mice; Myocardial Reperfusion Injury; Neprilysin; ST Elevation Myocardial Infarction; Substance P; Survival Analysis; Tetrazoles; Valsartan; Ventricular Remodeling | 2020 |
Between two storms, vasoactive peptides or bradykinin underlie severity of COVID-19?
Topics: Animals; Bradykinin; COVID-19; Cytokines; Humans; Microvessels; Neprilysin; Neurotensin; Post-Acute COVID-19 Syndrome; Substance P | 2021 |
16 trial(s) available for substance p and bradykinin
| Article | Year |
|---|---|
Bradykinin-induced cough reflex markedly increases in patients with cough associated with captopril and enalapril.
Topics: Adult; Aerosols; Aged; Bradykinin; Captopril; Citrates; Citric Acid; Cough; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Reflex; Respiratory Function Tests; Substance P | 1991 |
Effect of NG-monomethyl-L-arginine on kinin-induced vasodilation in the human forearm.
Topics: Adult; Analysis of Variance; Arginine; Brachial Artery; Bradykinin; Drug Interactions; Endothelium, Vascular; Forearm; Humans; Infusions, Intra-Arterial; Male; Nitric Oxide; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Substance P; Vasodilation | 1994 |
Effect of procaterol, a beta 2-adrenoceptor agonist, on skin whealing response caused by inflammatory mediators in asthmatic children.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bradykinin; Child; Cross-Over Studies; Female; Histamine; Humans; Male; Platelet Activating Factor; Procaterol; Skin; Skin Tests; Substance P | 1995 |
Chronopharmacology of enalapril in hypertensive patients.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Cough; Dinoprostone; Enalapril; Enalaprilat; Female; Half-Life; Humans; Hypertension; Male; Middle Aged; Substance P | 1995 |
Resolution of ACE inhibitor cough: changes in subjective cough and responses to inhaled capsaicin, intradermal bradykinin and substance-P.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Capsaicin; Cough; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Substance P | 1995 |
The ACE gene polymorphism and cough threshold for capsaicin after cilazapril usage.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Bronchial Provocation Tests; Capsaicin; Cilazapril; Cough; Cross-Over Studies; Double-Blind Method; Female; Genetic Predisposition to Disease; Genotype; Humans; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Skin Tests; Substance P | 2001 |
Forearm blood flow and local responses to peptide vasodilators: a novel pharmacodynamic measure in the phase I trial of antagonist G, a neuropeptide growth factor antagonist.
Topics: Adult; Aged; Antineoplastic Agents; Brachial Artery; Bradykinin; Dose-Response Relationship, Drug; Female; Flushing; Forearm; Humans; Infusion Pumps; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Neuropeptides; Oligopeptides; Regional Blood Flow; Substance P; Treatment Outcome; Vasodilator Agents | 2001 |
Bradykinin contributes to the vasodilator effects of chronic angiotensin-converting enzyme inhibition in patients with heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Female; Forearm; Heart Failure; Heart Rate; Humans; Infusions, Intravenous; Male; Middle Aged; Plethysmography; Reference Values; Regional Blood Flow; Substance P; Vasodilation | 2001 |
Potentiation of bradykinin-induced tissue plasminogen activator release by angiotensin-converting enzyme inhibition.
Topics: Adult; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Brachial Artery; Bradykinin; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Endothelium, Vascular; Fibrinolysis; Forearm; Humans; Infusions, Intravenous; Isoquinolines; Losartan; Male; Nitroprusside; Plethysmography, Impedance; Quinapril; Substance P; Tetrahydroisoquinolines; Tissue Plasminogen Activator; Vasodilator Agents | 2001 |
Evidence for agonist-specific endothelial vasodilator dysfunction with ageing in healthy humans.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adult; Aged; Aging; Blood Pressure; Body Composition; Bradykinin; Endothelium, Vascular; Forearm; Humans; Infusions, Intra-Arterial; Isoproterenol; Male; Middle Aged; Nitroprusside; Regional Blood Flow; Substance P; Vasodilation; Vasodilator Agents; Vital Capacity | 2002 |
Local tissue factor pathway inhibitor release in the human forearm.
Topics: Adult; Bradykinin; Endothelium, Vascular; Forearm; Hemodynamics; Heparin; Humans; Infusions, Intra-Arterial; Lipoproteins; Male; Nitroprusside; Regional Blood Flow; Substance P; Vasodilator Agents | 2003 |
An in vivo microanalytical technique for measuring the local biochemical milieu of human skeletal muscle.
Topics: Bradykinin; Calcitonin Gene-Related Peptide; Electromyography; Humans; Hydrogen-Ion Concentration; Microdialysis; Muscle Contraction; Muscle, Skeletal; Norepinephrine; Pain Threshold; Serotonin; Substance P; Tumor Necrosis Factor-alpha | 2005 |
The inhibitory effects of local anaesthetics on the vascular flare responses to bradykinin and substance P in human skin.
Topics: Adult; Amides; Anesthetics, Local; Bradykinin; Bupivacaine; Double-Blind Method; Humans; Laser-Doppler Flowmetry; Levobupivacaine; Lidocaine; Male; Regional Blood Flow; Ropivacaine; Skin; Substance P; Vasodilator Agents | 2008 |
Impaired endothelium-dependent vasodilation in overweight and obese adult humans is not limited to muscarinic receptor agonists.
Topics: Acetylcholine; Adult; Aged; Body Mass Index; Bradykinin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Infusions, Intravenous; Isoproterenol; Male; Methacholine Chloride; Middle Aged; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Obesity; Regional Blood Flow; Signal Transduction; Substance P; Vasodilation; Vasodilator Agents | 2008 |
Intra-articular opioid analgesia is effective in reducing pain and inflammation in an equine LPS induced synovitis model.
Topics: Analgesics, Opioid; Animals; Bradykinin; Cross-Over Studies; Dinoprostone; Female; Horse Diseases; Horses; Inflammation; Injections, Intra-Articular; Lipopolysaccharides; Morphine; Pain; Proteins; Substance P; Synovial Fluid; Synovitis | 2010 |
Substance P increases sympathetic activity during combined angiotensin-converting enzyme and dipeptidyl peptidase-4 inhibition.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Cross-Over Studies; Dipeptidyl Peptidase 4; Double-Blind Method; Enalaprilat; Enzyme Inhibitors; Female; Heart Rate; Humans; Male; Middle Aged; Neurotransmitter Agents; Norepinephrine; Peptidyl-Dipeptidase A; Pyrazines; Sitagliptin Phosphate; Substance P; Sympathetic Nervous System; Triazoles; Vascular Resistance | 2014 |
508 other study(ies) available for substance p and bradykinin
| Article | Year |
|---|---|
Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists.
Topics: Calcium; Cell Line; Drug Discovery; Humans; Neuropeptides; Receptors, G-Protein-Coupled; Structure-Activity Relationship | 2009 |
Biochemical basis of analgesia: metabolism, storage, regulation, and action.
Topics: Analgesia; Bradykinin; Dopamine; Enkephalins; Glutamates; Histamine; Neurotransmitter Agents; Norepinephrine; Opium; Pain; Prostaglandins; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Serotonin; Substance P | 1978 |
[Role of peptides in central neural transmission: substance P, bradykinin and beta-endorphine].
Topics: Animals; Bradykinin; Cats; Endorphins; Nociceptors; Proprioception; Rats; Receptors, Opioid; Spinal Nerves; Substance P; Synaptic Transmission | 1978 |
Effects of intra-arterial bradykinin and substance P on isolated, blood-perfused small intestine of the rat.
Topics: Animals; Blood; Bradykinin; Hexamethonium Compounds; Ileum; In Vitro Techniques; Injections, Intra-Arterial; Male; Morphine; Muscle Contraction; Muscle, Smooth; Perfusion; Rats; Substance P; Tetrodotoxin | 1979 |
Effect of intracerebroventricular bradykinin, angiotensin II, and substance P on multiple fixed-interval fixed-ratio responding in rabbits.
Topics: Angiotensin II; Animals; Atropine; Bradykinin; Conditioning, Operant; Injections, Intraventricular; Male; Morphine; Naloxone; Rabbits; Reinforcement Schedule; Substance P; Time Factors | 1978 |
Centrally administered neurotensin: activity in the Julou-Courvoisier muscle relaxation test in mice.
Topics: Animals; Bradykinin; Cisterna Magna; In Vitro Techniques; Injections; Male; Mice; Muscle Contraction; Muscle Relaxation; Neurotensin; Substance P; Thyrotropin-Releasing Hormone; Time Factors | 1979 |
Effects of synthetic substance P on unit-discharges of testicular nociceptors of dogs.
Topics: Acetylcholine; Animals; Bradykinin; Chemoreceptor Cells; Dogs; Evoked Potentials; Histamine; Male; Neural Conduction; Nociceptors; Potassium Chloride; Sodium Chloride; Spermatic Cord; Substance P; Synaptic Transmission; Testis; Thermoreceptors | 1979 |
Excitation of neurons in the nucleus locus coeruleus by substance P and related peptides.
Topics: Acetylcholine; Animals; Bradykinin; Eledoisin; Enkephalins; Epinephrine; Evoked Potentials; Locus Coeruleus; Male; Neurons; Neurotensin; Norepinephrine; Physalaemin; Rats; Substance P; Thyrotropin-Releasing Hormone | 1977 |
[A study on the biological action of hypothalamic tridecapeptide, neurotensin (author's transl)].
Topics: Animals; Blood Pressure; Bradykinin; Castration; Duodenum; Estrogens; Female; Follicle Stimulating Hormone; Guinea Pigs; Ileum; In Vitro Techniques; Luteinizing Hormone; Muscle Contraction; Neurotensin; Progesterone; Prolactin; Rats; Substance P; Uterine Contraction | 1979 |
An attempt to differentiate the effects of angiotensin II, substance P and bradykinin on the field-stimulated guinea-pig vas deferens.
Topics: Angiotensin II; Animals; Bradykinin; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Oligopeptides; Saralasin; Substance P; Vas Deferens | 1979 |
Interaction between arterial pressure and vasoactive hormones in the release of renal kallikrein.
Topics: Acetylcholine; Angiotensins; Animals; Blood Pressure; Bradykinin; Dogs; Dopamine; Eledoisin; Isoproterenol; Kallikreins; Kidney; Norepinephrine; Osmolar Concentration; Prostaglandins E; Sodium; Substance P; Urine | 1979 |
The actions of some vasoactive polypeptides and their antagonists on the anococcygeus muscle.
Topics: Animals; Bradykinin; Cats; Eledoisin; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Rabbits; Rats; Substance P | 1978 |
Successive cleavage of N-terminal Arg1--Pro2 and Lys3-Pro4 from substance P but no release of Arg1-Pro2 from bradykinin, by X-Pro dipeptidyl-aminopeptidase.
Topics: Amino Acid Sequence; Amino Acids; Bradykinin; Cathepsins; Humans; Kinetics; Substance P; Substrate Specificity | 1978 |
Functional identification of units in the rat dorsal horn responding to a substance P analogue [proceedings].
Topics: Action Potentials; Animals; Bradykinin; Male; Neurons; Rats; Spinal Cord; Substance P | 1978 |
Neuronal responses to bradykinin.
Topics: Action Potentials; Animals; Bradykinin; Central Nervous System; Interneurons; Neurons; Pain; Rats; Spinal Cord; Substance P; Substantia Nigra | 1978 |
The hydrolysis of biologically active peptides by bovine lung tissue factor (thromboplastin).
Topics: Angiotensin II; Animals; Bradykinin; Cattle; Fibrinopeptide A; Gonadotropin-Releasing Hormone; Hydrolysis; Lung; Macrophage Migration-Inhibitory Factors; Mercaptoethanol; Oxytocin; Substance P; Thromboplastin | 1976 |
Relationship of spasmogenic and smooth muscle relaxant peptides from normal lung to other vasoactive compounds.
Topics: Angiotensin II; Animals; Bradykinin; Cross Reactions; Lung; Muscle Contraction; Muscle, Smooth; Peptides; Prostaglandins; Substance P; Swine; Vasoactive Intestinal Peptide; Vasodilator Agents | 1977 |
Effect of kallidin, substance P, and other basic polypeptides on the production of respiratory macromolecules.
Topics: Animals; Bradykinin; Dogs; Eledoisin; Galactose; Galactosyltransferases; Glycoproteins; Hexadimethrine Bromide; Kallidin; Male; Mucous Membrane; Peptides; Physalaemin; Substance P; Trachea | 1977 |
Does indomethacin antagonize the effects of peptides and other agents on the coronary circulation of rabbit isolated hearts.
Topics: Animals; Bradykinin; Coronary Circulation; Fatty Acids; In Vitro Techniques; Indomethacin; Peptides; Prostaglandins E; Prostaglandins F; Rabbits; Substance P | 1977 |
Interactions of substance P with putative mediators of inflammation and ATP.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Capillary Permeability; Drug Interactions; Histamine; Inflammation; Male; Prostaglandins E; Rats; Serotonin; Substance P | 1977 |
Effects of substance P on functionally identified units in cat spinal cord.
Topics: Acetylcholine; Animals; Bradykinin; Cats; Evoked Potentials; Glutamates; Hot Temperature; Neurons; Norepinephrine; Serotonin; Spinal Cord; Substance P; Touch | 1976 |
The action of some vasoactive polypeptides and their antagonists on the anococcygeus muscle [proceedings].
Topics: Animals; Bradykinin; Eledoisin; In Vitro Techniques; Muscles; Neural Inhibition; Rats; Substance P | 1976 |
Release of prostaglandins by bradykinin as an intrinsic mechanism of its algesic effect.
Topics: Acetylcholine; Animals; Bradykinin; Denervation; Ear; Indomethacin; Pain; Prostaglandins; Prostaglandins E; Rabbits; Substance P | 1976 |
Further characterization of endopeptidase H2 a serine proteinase from human urine.
Topics: Amino Acid Sequence; Bradykinin; Endopeptidases; Humans; Hydrolysis; Kinetics; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Serine Endopeptidases; Substance P; Substrate Specificity | 1992 |
Effect of nitro-L-arginine on endothelium-dependent hyperpolarizations and relaxations of pig coronary arteries.
Topics: Animals; Arginine; Bradykinin; Coronary Vessels; Dinoprost; Dose-Response Relationship, Drug; Endothelium; In Vitro Techniques; Indomethacin; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Prostaglandin Antagonists; Substance P; Swine | 1992 |
Endothelium-derived nitric oxide and cyclooxygenase products modulate corpus cavernosum smooth muscle tone.
Topics: Acetylcholine; Animals; Bradykinin; Cholic Acids; Cyclic GMP; Eicosanoids; Endothelium, Vascular; Guanylate Cyclase; Humans; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Neurotransmitter Agents; Nitric Oxide; Nitroprusside; Papaverine; Penis; Prostaglandin-Endoperoxide Synthases; Rabbits; Substance P; Vasoactive Intestinal Peptide | 1992 |
Effects of capsaicin, bradykinin and prostaglandin E2 in the human skin.
Topics: Adult; Axons; Bradykinin; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Humans; Indomethacin; Inflammation; Lidocaine; Middle Aged; p-Methoxy-N-methylphenethylamine; Pyrilamine; Skin; Substance P; Tachyphylaxis; Time Factors; Vasodilation | 1992 |
A membrane-bound metallo-endopeptidase from rat kidney. Characteristics of its hydrolysis of peptide hormones and neuropeptides.
Topics: Amino Acid Sequence; Angiotensin I; Animals; Atrial Natriuretic Factor; Bradykinin; Chromatography, High Pressure Liquid; Endothelins; Hormones; Hydrolysis; Kidney; Kinetics; Metalloendopeptidases; Molecular Sequence Data; Neuropeptides; Neurotensin; Peptide Mapping; Peptides; Protein Conformation; Rats; Substance P | 1992 |
Endopeptidase 24.15 modulates bradykinin-induced contraction in guinea-pig trachea.
Topics: Amino Acid Sequence; Animals; Bradykinin; Dose-Response Relationship, Drug; Guinea Pigs; Male; Metalloendopeptidases; Molecular Sequence Data; Muscle Contraction; Oligopeptides; Peptidyl-Dipeptidase A; Substance P; Thiorphan; Trachea | 1992 |
Different patterns of release of endothelium-derived relaxing factor and prostacyclin.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arachidonic Acid; Arginine; Bradykinin; Cattle; Endothelium, Vascular; Epoprostenol; Hydrogen-Ion Concentration; In Vitro Techniques; Nitric Oxide; Rabbits; Radioimmunoassay; Substance P | 1992 |
Peptide mediator effects on bronchial blood velocity and lung resistance in conscious sheep.
Topics: Airway Resistance; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Bradykinin; Bronchi; Calcitonin Gene-Related Peptide; Lung; Neprilysin; Peptides; Sheep; Substance P | 1992 |
Involvement of capsaicin-sensitive neurones in the haemodynamic effects of exogenous vasoactive peptides: studies in conscious, adult Long Evans rats treated neonatally with capsaicin.
Topics: Analysis of Variance; Animals; Animals, Newborn; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Cholecystokinin; Hemodynamics; Neurons; Neuropeptides; Rats; Substance P; Vasoconstrictor Agents; Vasodilator Agents | 1992 |
The interactions of neuropeptides with membrane model systems: a case study.
Topics: Bradykinin; Enkephalin, Methionine; Lysophosphatidylcholines; Magnetic Resonance Spectroscopy; Membranes, Artificial; Micelles; Phenylalanine; Substance P | 1992 |
Stimulation of inositol phosphate formation in cultured human retinal pigment epithelium.
Topics: Angiotensin II; Arginine Vasopressin; Bombesin; Bradykinin; Carbachol; Cells, Cultured; Epoprostenol; Histamine; Humans; Inositol; Inositol Phosphates; Kinetics; Norepinephrine; Parasympathomimetics; Pigment Epithelium of Eye; Protease Inhibitors; Serotonin; Substance P; Thrombin; Vasopressins | 1992 |
Effect of resiniferatoxin on the isolated rabbit iris sphincter muscle: comparison with capsaicin and bradykinin.
Topics: Animals; Bradykinin; Capsaicin; Captopril; Diterpenes; Electric Stimulation; Female; Iris; Male; Muscle Contraction; Rabbits; Substance P; Tachykinins; Tachyphylaxis; Thiorphan | 1992 |
Effects of interleukin-1 receptor antagonist on three types of responses to interleukin-1 in rabbit isolated blood vessels.
Topics: Animals; Blood Vessels; Bradykinin; Dose-Response Relationship, Drug; Iloprost; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Norepinephrine; Phenylephrine; Proteins; Rabbits; Receptors, Immunologic; Receptors, Interleukin-1; Recombinant Proteins; Sialoglycoproteins; Substance P; Vasoconstriction; Vasodilation | 1992 |
[Asthma due to airway inflammation].
Topics: Airway Resistance; Animals; Asthma; Bradykinin; Bronchi; Bronchial Hyperreactivity; Bronchitis; Cytokines; Humans; Leukocytes; Substance P | 1992 |
[Cough as a side effect of angiotensin-converting enzyme inhibitors].
Topics: Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Bronchial Hyperreactivity; Cough; Dinoprostone; Humans; Substance P | 1992 |
Carboxypeptidase M-like enzyme modulates the noncholinergic bronchoconstrictor response in guinea pig.
Topics: 3-Mercaptopropionic Acid; Animals; Bradykinin; Bronchoconstriction; Capsaicin; Electric Stimulation; GPI-Linked Proteins; Guinea Pigs; Histamine; Male; Metalloendopeptidases; Neurokinin A; Receptors, Cholinergic; Substance P; Vagus Nerve | 1992 |
The effects of calcitonin gene-related peptide on formation of intra-articular oedema by inflammatory mediators.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Dose-Response Relationship, Drug; Edema; Histamine; Joint Diseases; Male; Rats; Rats, Wistar; Substance P | 1992 |
Thimerosal blocks stimulated but not basal release of endothelium-derived relaxing factor (EDRF) in dog isolated coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arginine; Arteries; Bradykinin; Calcimycin; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Substance P; Thimerosal; Vasoconstrictor Agents | 1992 |
Effects of nitric oxide synthase inhibitors, L-NG-nitroarginine and L-NG-nitroarginine methyl ester, on responses to vasodilators of the guinea-pig coronary vasculature.
Topics: Adenosine Triphosphate; Animals; Arginine; Bradykinin; Coronary Vessels; Female; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroarginine; Nitroprusside; Serotonin; Substance P; Vasodilation; Vasodilator Agents | 1992 |
Comparison of cyclic GMP in human internal mammary artery and saphenous vein: implications for coronary artery bypass graft patency.
Topics: Acetylcholine; Bradykinin; Coronary Artery Bypass; Culture Techniques; Cyclic GMP; Endothelium, Vascular; Graft Occlusion, Vascular; Humans; Mammary Arteries; Nitroglycerin; Saphenous Vein; Substance P; Vascular Patency | 1992 |
Release of sensory neuropeptides from dural venous sinuses of guinea pig.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Cranial Sinuses; Female; Guinea Pigs; In Vitro Techniques; Male; Neurons, Afferent; Potassium; Substance P | 1990 |
A bradykinin (BK)1 receptor antagonist blocks capsaicin-induced ear inflammation in mice.
Topics: Animals; Bradykinin; Capsaicin; Ear, External; Edema; Inflammation; Male; Mice; Receptors, Bradykinin; Receptors, Neurotransmitter; Substance P | 1990 |
Effects of capsaicin, tachykinins, calcitonin gene-related peptide and bradykinin in the pig iris sphincter muscle.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; In Vitro Techniques; Iris; Neurokinin A; Radioimmunoassay; Substance P; Swine; Tachykinins | 1990 |
A possible coupling of postjunctional ATP release and transmitters' receptor stimulation in smooth muscles.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Bethanechol; Bethanechol Compounds; Bradykinin; Dinoprost; Guinea Pigs; Histamine; Ileum; Male; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Nifedipine; Norepinephrine; Potassium Chloride; Prazosin; Receptors, Neurotransmitter; Serotonin; Substance P | 1990 |
A neuropeptide antagonist that inhibits the growth of small cell lung cancer in vitro.
Topics: Animals; Bradykinin; Calcium; Carcinoma, Small Cell; Cell Division; Cells, Cultured; DNA, Neoplasm; Drug Screening Assays, Antitumor; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Mice; Peptide Fragments; Peptides; Recombinant Proteins; Substance P; Tumor Cells, Cultured; Vasopressins | 1990 |
[Cough reflex in respiratory disease].
Topics: Aged; Bradykinin; Cough; Female; Humans; Male; Pneumonia, Aspiration; Reflex; Respiratory Tract Infections; Substance P | 1990 |
Angiotensin converting enzyme inhibitors potentiate the bronchoconstriction induced by substance P in the guinea-pig.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bronchi; Capsaicin; Captopril; Drug Synergism; Enalaprilat; Guinea Pigs; In Vitro Techniques; Male; Neuropeptides; Prazosin; Serotonin; Substance P | 1990 |
Auranofin inhibits histamine release from rat peritoneal mast cells.
Topics: Animals; Auranofin; Bradykinin; Cells, Cultured; Fibroblasts; Histamine Release; Lymphocyte Activation; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Rats; Substance P | 1990 |
Basal and stimulated release of substance P from dissociated cultures of vagal sensory neurons.
Topics: Animals; Animals, Newborn; Bradykinin; Capsaicin; Chromatography, High Pressure Liquid; Kinetics; Neurons, Afferent; Nodose Ganglion; Phorbol 12,13-Dibutyrate; Potassium; Rats; Rats, Inbred Strains; Substance P; Vagus Nerve | 1990 |
Peptide QSAR on substance P analogues, enkephalins and bradykinins containing L- and D-amino acids.
Topics: Amino Acid Sequence; Animals; Bradykinin; Enkephalins; Female; Guinea Pigs; Ileum; Male; Mice; Molecular Sequence Data; Rats; Stereoisomerism; Structure-Activity Relationship; Substance P; Uterus; Vas Deferens | 1990 |
Studies on the vascular permeability induced by intrathecal substance P and bradykinin in the rat.
Topics: Adrenalectomy; Animals; Blood Proteins; Bradykinin; Capillary Permeability; Capsaicin; Decerebrate State; In Vitro Techniques; Injections, Spinal; Male; Neurokinin A; Neurokinin B; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Vagotomy | 1990 |
Implication of polymodal receptor activities in intraocular pressure elevation by neurogenic inflammation.
Topics: Animals; Anterior Chamber; Aspirin; Bradykinin; Female; Glucose; Intraocular Pressure; Male; Neuritis; Procaine; Rabbits; Receptors, Cell Surface; Receptors, Drug; Sodium Chloride; Substance P; Tachyphylaxis | 1990 |
Low basal and stimulated release of nitric oxide in atherosclerotic epicardial coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adolescent; Adult; Arginine; Arteriosclerosis; Bradykinin; Child; Child, Preschool; Coronary Vessels; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Humans; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Substance P; Vasoconstriction; Vasodilation | 1990 |
Mechanisms of mediator release from human skin mast cells upon stimulation by the bradykinin analog, [DArg0-Hyp3-DPhe7]bradykinin.
Topics: Antibodies, Anti-Idiotypic; Bradykinin; Calcium; Cells, Cultured; Cyclic AMP; Histamine; Humans; Immunoglobulin E; Mast Cells; Protein Kinase C; Signal Transduction; Skin; Substance P | 1991 |
Airway effects of inhaled bradykinin, substance P, and neurokinin A in sheep.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Antigens, Helminth; Ascaris; Bradykinin; Bronchoconstriction; Bronchoconstrictor Agents; Carbachol; Dose-Response Relationship, Drug; Hypersensitivity; Neurokinin A; Sheep; Substance P | 1991 |
Heterogeneity in conducted arteriolar vasomotor response is agonist dependent.
Topics: Acetylcholine; Adenosine; Animals; Arterioles; Bradykinin; Cricetinae; Iontophoresis; Isoproterenol; Male; Mesocricetus; Muscarine; Papaverine; Phenylephrine; Substance P; Vasomotor System | 1991 |
Metabolism of substance P and bradykinin by human neutrophils.
Topics: Amino Acid Sequence; Bradykinin; Cathepsin G; Cathepsins; Cell Membrane; Cytochalasin B; Humans; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neprilysin; Neutrophils; Serine Endopeptidases; Subcellular Fractions; Substance P; Tetradecanoylphorbol Acetate | 1991 |
Selectivity and specificity of new, non-peptide, quinuclidine antagonists of substance P.
Topics: Angiotensin II; Animals; Blood Vessels; Bradykinin; Cell Line; Guinea Pigs; Humans; Muscle Contraction; Norepinephrine; Quinuclidines; Rabbits; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P | 1991 |
[Changes in the intracellular free calcium of cultured human epidermal keratinocytes].
Topics: Adenosine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Bradykinin; Bucladesine; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Epidermal Cells; Epinephrine; Histamine; Humans; Keratinocytes; Substance P; Thrombin; Type C Phospholipases | 1991 |
Mechanism of action of substance P in guinea-pig ileum longitudinal smooth muscle: a re-evaluation.
Topics: Animals; Bradykinin; Carbachol; Cell Membrane Permeability; Eledoisin; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Potassium; Propranolol; Substance P; Tetraethylammonium; Tetraethylammonium Compounds | 1990 |
Morphine, but not sodium cromoglycate, modulates the release of substance P from capsaicin-sensitive neurones in the rat trachea in vitro.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Bradykinin; Capsaicin; Cromolyn Sodium; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Naloxone; Neurons; Potassium Chloride; Pyrrolidines; Rats; Rats, Inbred Strains; Substance P; Trachea | 1991 |
Low level hyperlipidemia impairs endothelium-dependent relaxation of porcine coronary arteries by two mechanisms. Functional change in endothelium and impairment of endothelium-dependent relaxation by two mediators.
Topics: Animals; Bradykinin; Calcimycin; Cholesterol; Coronary Vessels; Endothelium, Vascular; Hyperlipidemias; In Vitro Techniques; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Serotonin; Substance P; Swine | 1991 |
Postnatal development of neurogenic inflammation in the rat.
Topics: Aging; Animals; Animals, Newborn; Bradykinin; Dermatitis; Histamine; Injections, Intradermal; Nervous System Physiological Phenomena; Plasma; Rats; Rats, Inbred Strains; Skin; Substance P | 1991 |
G-proteins as targets for non-immunological histamine releasers.
Topics: Animals; Bradykinin; GTP-Binding Proteins; Histamine Release; Intercellular Signaling Peptides and Proteins; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Peptides; Pertussis Toxin; Rats; Rats, Inbred Strains; Spermine; Substance P; Virulence Factors, Bordetella; Wasp Venoms | 1991 |
Calcitonin gene-related peptide is a potent vasodilator of bovine retinal arteries in vitro.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Cattle; Dose-Response Relationship, Drug; In Vitro Techniques; Retinal Vessels; Ruthenium Red; Substance P; Vasodilator Agents | 1991 |
On-line measurement of nitric oxide release from organic nitrates in the intact coronary circulation.
Topics: Animals; Arginine; Bradykinin; Coronary Vessels; In Vitro Techniques; Molsidomine; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Oxyhemoglobins; Rabbits; Substance P; Trypsin; Vasodilation | 1991 |
Effects of cilazaprilat and enalaprilat on experimental dermatitis in guinea pigs.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cilazapril; Dermatitis; Drug Synergism; Enalaprilat; Erythema; Female; Guinea Pigs; Inflammation; Ovalbumin; Pyridazines; Substance P | 1991 |
Activation of primary afferents in the rabbit ear by noxious heat.
Topics: Afferent Pathways; Animals; Bradykinin; Capsaicin; Ear; Hot Temperature; Pain; Potassium; Rabbits; Substance P | 1991 |
Characterization of bradykinin receptors in peripheral organs.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Bradykinin; Cricetinae; Guinea Pigs; In Vitro Techniques; Indomethacin; Jugular Veins; Leukotriene Antagonists; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Neurokinin A; Polyphloretin Phosphate; Prostaglandin Antagonists; Quinolines; Rabbits; Rats; Receptors, Bradykinin; Receptors, Neurotransmitter; Substance P; Trachea; Urinary Bladder | 1991 |
Pain, tenderness, wheal and flare induced by substance-P, bradykinin and 5-hydroxytryptamine in humans.
Topics: Adult; Bradykinin; Female; Forearm; Humans; Male; Muscles; Pain; Serotonin; Skin; Skin Tests; Substance P | 1991 |
Pharmacological evaluation of the angiotensin, kinin, and neurokinin receptors on the rabbit vena cava.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Bradykinin; Calcium; Calcium Channel Blockers; Calcium Channels; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Channels; Rabbits; Receptors, Angiotensin; Receptors, Bradykinin; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Sodium Channels; Substance P; Vena Cava, Inferior | 1991 |
Responses of porcine gastric and duodenal smooth muscle to VIP.
Topics: Acetylcholine; Animals; Bombesin; Bradykinin; Dinoprostone; Duodenum; Electric Stimulation; Gastrointestinal Motility; In Vitro Techniques; Muscle, Smooth; Serotonin; Stomach; Substance P; Swine; Vasoactive Intestinal Peptide | 1991 |
Neurokinins produce selective venoconstriction via NK-3 receptors in the rat mesenteric vascular bed.
Topics: Acetylcholine; Animals; Bradykinin; Cholic Acids; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Perfusion; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Tachykinin; Splanchnic Circulation; Structure-Activity Relationship; Substance P; Vasoconstriction; Vasodilation | 1991 |
Involvement of afferent nerves in pulpal blood-flow reactions in response to clinical and experimental procedures in the cat.
Topics: Administration, Topical; Animals; Bradykinin; Capsaicin; Cats; Dental Cavity Preparation; Dental Pulp; Electric Stimulation; Ganglia, Sympathetic; Injections, Intravenous; Lasers; Male; Mandibular Nerve; Neurons, Afferent; Percussion; Regional Blood Flow; Substance P; Tooth | 1991 |
Sugar-specific inhibitory effects of wheat germ agglutinin and phytohemagglutinin-E4 on histamine release induced by basic secretagogues from rat peritoneal mast cells and their possible action sites.
Topics: Acetylgalactosamine; Acetylglucosamine; Animals; Binding Sites; Bradykinin; Histamine Release; Lectins; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Phytohemagglutinins; Plant Lectins; Plants, Toxic; Polyethyleneimine; Rats; Rats, Inbred Strains; Ricinus communis; Substance P; Wheat Germ Agglutinins | 1991 |
A comparison of endothelium-derived relaxing factor activity in the coronary and renal arteries of the pig.
Topics: Animals; Bradykinin; Coronary Vessels; Nitric Oxide; Nitroprusside; Renal Artery; Substance P; Swine | 1991 |
Effect of the new antiallergic drug epinastine on chemical mediator induced bronchoconstrictions in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bradykinin; Bronchoconstriction; Dibenzazepines; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Neurokinin A; Phthalazines; Piperazines; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; SRS-A; Substance P | 1991 |
Nerve-induced tachykinin-mediated vasodilation in skeletal muscle is dependent on nitric oxide formation.
Topics: Animals; Arginine; Atropine; Bradykinin; Calcitonin Gene-Related Peptide; Dinoprostone; Dose-Response Relationship, Drug; Electric Stimulation; Hindlimb; Hyperemia; Muscles; Neurokinin A; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pancuronium; Rabbits; Substance P; Tachykinins; Vasodilation | 1991 |
Central and local actions of opioids upon reticulo-ruminal motility in sheep.
Topics: Animals; Bradykinin; Enkephalins; Gastrointestinal Motility; In Vitro Techniques; Loperamide; Morphine Derivatives; Muscle Contraction; Naloxone; Narcotics; Prostaglandins E; Reticulum; Rumen; Sheep; Substance P | 1985 |
Mast cell heterogeneity: effects of neuroenteric peptides on histamine release.
Topics: Animals; Bradykinin; Calcium; Cell Separation; Energy Metabolism; Histamine Release; Hydrogen-Ion Concentration; Intestinal Mucosa; Kinetics; Mast Cells; Nerve Tissue Proteins; Rats; Rats, Inbred WF; Somatostatin; Substance P; Temperature; Vasoactive Intestinal Peptide | 1985 |
Activities and antagonism of bombesin on urinary smooth muscles.
Topics: Animals; Atropine; Bombesin; Bradykinin; Guinea Pigs; In Vitro Techniques; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Oligopeptides; Peptides; Propranolol; Rats; Rats, Inbred Strains; Substance P; Urinary Bladder | 1985 |
Prostaglandins enhance trigeminal substance P-ergic responses in the rabbit iris sphincter muscles.
Topics: Animals; Bradykinin; Electric Stimulation; In Vitro Techniques; Indomethacin; Iris; Neuromuscular Junction; Prostaglandins; Rabbits; Substance P; Synaptic Transmission; Trigeminal Nerve | 1985 |
Substance P antagonists and mucociliary activity in rabbit.
Topics: Animals; Bradykinin; Capsaicin; Cilia; Female; Male; Maxillary Sinus; Methacholine Chloride; Methacholine Compounds; Peptide Fragments; Rabbits; Substance P; Time Factors | 1985 |
[Endogenous peptides in the organization of somato-vegetative responses to hypothalamic stimulation].
Topics: Angiotensin II; Animals; beta-Endorphin; Bradykinin; Chinchilla; Delta Sleep-Inducing Peptide; Endorphins; Escape Reaction; Hypothalamus; Male; Oligopeptides; Peptides; Renin; Self Stimulation; Substance P | 1985 |
Peptide hormones and their possible functions in the normal and abnormal lung.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Animals; Bradykinin; Calcitonin; Endorphins; Gastrointestinal Hormones; Hormones; Humans; Lung; Neurotensin; Peptides; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1985 |
Inflammatory oedema induced by synergism between calcitonin gene-related peptide (CGRP) and mediators of increased vascular permeability.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Complement C5; Complement C5a, des-Arginine; Dinoprostone; Drug Synergism; Edema; Histamine; Inflammation; Injections, Intradermal; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Platelet Activating Factor; Prostaglandins E; Rabbits; Rats; Rats, Inbred Lew; Skin; Species Specificity; Substance P | 1985 |
Peptides and histamine release from rat peritoneal mast cells.
Topics: Animals; Bradykinin; Histamine Release; In Vitro Techniques; Kallidin; Kinins; Mast Cells; Nerve Tissue Proteins; Peptides; Peritoneal Cavity; Rats; Rats, Inbred Strains; Substance P; Tachykinins | 1985 |
Synaptosomal degradation of substance P and some other neuropeptides.
Topics: Animals; Bradykinin; Brain; Female; Hydrogen-Ion Concentration; Kinetics; Luteinizing Hormone; Male; Nerve Tissue Proteins; Neurotensin; Peptide Fragments; Peptide Hydrolases; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Synaptosomes; Thyrotropin-Releasing Hormone | 1985 |
Substance P, 5-hydroxytryptamine, and bradykinin stimulate abdominal visceral afferents.
Topics: Abdomen; Animals; Bradykinin; Cats; Female; Male; Nerve Fibers; Nerve Fibers, Myelinated; Neural Conduction; Neurons, Afferent; Serotonin; Stimulation, Chemical; Substance P | 1986 |
Effect of DL-2-mercaptomethyl-3-guanidinoethylthiopropanoic acid on the blood pressure response to vasoactive substances.
Topics: 3-Mercaptopropionic Acid; Acetylcholine; Angiotensins; Animals; Arginine Vasopressin; Blood Pressure; Bradykinin; Carboxypeptidases; Eledoisin; Lysine Carboxypeptidase; Male; Nitroprusside; Phenylephrine; Rats; Substance P; Sulfhydryl Compounds | 1986 |
Effects of noxious stimuli and anesthetic agents on substance P content in rat central nervous system.
Topics: Anesthetics; Animals; Bradykinin; Central Nervous System; Dental Pulp; Electric Stimulation; Male; Rats; Rats, Inbred Strains; Substance P | 1986 |
Immunomodulation by some oligopeptides.
Topics: Adjuvants, Immunologic; Animals; Bradykinin; Chemotaxis, Leukocyte; Concanavalin A; Electrophoresis; In Vitro Techniques; Lymphocytes; Lymphokines; Mice; Mice, Inbred CBA; Oligopeptides; Rats; Rats, Inbred Strains; Substance P | 1986 |
Failure of microscopic metarterioles to elicit vasodilator responses to acetylcholine, bradykinin, histamine and substance P after ischemic shock, endotoxemia and trauma: possible role of endothelial cells.
Topics: Acetylcholine; Animals; Arteries; Arterioles; Bradykinin; Histamine; Male; Mesenteric Arteries; Rats; Rats, Inbred Strains; Shock; Substance P; Toxemia; Vasodilation; Vasodilator Agents; Wounds and Injuries | 1985 |
Thrombin stimulates c-sis gene expression in microvascular endothelial cells.
Topics: Angiotensin II; Bradykinin; Cells, Cultured; Endothelium; Fibroblast Growth Factors; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-2; Kidney; Microcirculation; Norepinephrine; Platelet-Derived Growth Factor; Protein Kinase C; RNA, Messenger; Substance P; Tetradecanoylphorbol Acetate; Thrombin; Time Factors | 1986 |
Effect of desensitization induced by adenosine 5'-triphosphate, substance P, bradykinin, serotonin, gamma-aminobutyric acid and endogenous noncholinergic-nonadrenergic transmitter in the guinea-pig ileum.
Topics: Adenosine Triphosphate; Animals; Bradykinin; gamma-Aminobutyric Acid; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Neurotransmitter Agents; Serotonin; Substance P; Synaptic Transmission | 1986 |
Interaction of bradykinin with substance P on vascular permeability and pain response.
Topics: Animals; Bradykinin; Capillary Permeability; Drug Synergism; Foot; Inflammation; Male; Mice; Pain; Substance P | 1986 |
Peptides increase anion conductance of canine trachea: an effect on tight junctions.
Topics: Animals; Anions; Bradykinin; Chlorides; Dogs; Electric Conductivity; Epithelium; Intercellular Junctions; Isethionic Acid; Membrane Potentials; Neuropeptides; Nitrates; Substance P; Tachykinins; Trachea | 1986 |
Capsaicin treatment attenuates the reflex excitation of sympathetic activity caused by chemical stimulation of intestinal afferent nerves.
Topics: Animals; Bradykinin; Capsaicin; Ganglia, Spinal; Intestines; Kidney; Male; Membrane Potentials; Neurons, Afferent; Radioimmunoassay; Rats; Reflex; Substance P; Sympathetic Nervous System | 1986 |
Neural activation of opioid mechanisms in guinea pig ileum by excitatory peptides.
Topics: Acetylcholine; Angiotensin II; Animals; Bombesin; Bradykinin; Cholecystokinin; Corticotropin-Releasing Hormone; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Endorphins; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Naloxone; Neuropeptides; Neurotensin; Receptors, Opioid; Substance P | 1987 |
Metabolism of neuropeptides. Hydrolysis of the angiotensins, bradykinin, substance P and oxytocin by pig kidney microvillar membranes.
Topics: Angiotensins; Animals; Bradykinin; Chromatography, High Pressure Liquid; Hydrolysis; Kidney; Microvilli; Oxytocin; Peptide Hydrolases; Peptides; Substance P; Swine | 1987 |
The effect of infusion of various peptide antisera on vasodilatation in the cat common carotid vascular territory.
Topics: Animals; Blood Pressure; Bradykinin; Carotid Arteries; Cats; Decerebrate State; Electric Stimulation; Ganglia, Parasympathetic; Immune Sera; Infusions, Intra-Arterial; Locus Coeruleus; Substance P; Vasoactive Intestinal Peptide; Vasodilation | 1985 |
Interaction of bradykinin and des-Arg9-bradykinin with isolated pig coronary arteries: mechanical and electrophysiological events.
Topics: Animals; Bradykinin; Coronary Vessels; Endothelium; In Vitro Techniques; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; Receptors, Bradykinin; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Swine | 1987 |
Effects of prostaglandins and other putative chemical intermediaries on the activity of canine testicular polymodal receptors studied in vitro.
Topics: Animals; Aspirin; Bradykinin; Dinoprostone; Dogs; Epoprostenol; In Vitro Techniques; Male; Nociceptors; Prostaglandins; Prostaglandins E; Saline Solution, Hypertonic; Serotonin; Substance P; Testis | 1987 |
Multiple tachykinin pools in sensory nerve fibres in the rabbit iris.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Iris; Male; Nerve Endings; Neurons, Afferent; Neuropeptides; Rabbits; Substance P; Tachykinins; Tachyphylaxis | 1987 |
Contribution of substance P to heat-induced edema in rat paw.
Topics: Animals; Bradykinin; Capsaicin; Denervation; Edema; Histamine; Hot Temperature; Male; Pyridazines; Rats; Rats, Inbred Strains; Substance P | 1987 |
Peptide receptors in the airways.
Topics: Animals; Bradykinin; Carotid Arteries; Dogs; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Neurokinin A; Neurokinin B; Neuropeptides; Portal Vein; Rats; Receptors, Neurotransmitter; Substance P; Trachea | 1987 |
The ability of des-Arg9-bradykinin to relax rabbit isolated mesenteric arteries is acquired during in vitro incubation.
Topics: Animals; Bradykinin; Cycloheximide; Endothelium, Vascular; Female; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Rabbits; Substance P | 1987 |
Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries.
Topics: Acetylcholine; Adolescent; Adult; Biological Products; Bradykinin; Calcimycin; Coronary Artery Disease; Coronary Vessels; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Middle Aged; Nitric Oxide; Nitroglycerin; Substance P; Vasodilation | 1988 |
Vasomotor responses of rat intracerebral arterioles to vasoactive intestinal peptide, substance P, neuropeptide Y, and bradykinin.
Topics: Animals; Arteries; Arterioles; Bradykinin; Brain; Cerebrovascular Circulation; Neuropeptide Y; Peptides; Rats; Rats, Inbred Strains; Substance P; Vasoactive Intestinal Peptide; Vasomotor System | 1988 |
Purine-induced depression of dorsal horn neurons in the cat spinal cord: enhancement by tachykinins.
Topics: Action Potentials; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bradykinin; Cats; gamma-Aminobutyric Acid; Neural Inhibition; Neurons; Neuropeptides; Physalaemin; Reaction Time; Spinal Cord; Substance P; Tachykinins | 1987 |
Characterization of the effects produced by neurokinins and three agonists selective for neurokinin receptor subtypes in a spinal nociceptive reflex of the rat.
Topics: Adrenalectomy; Animals; Bradykinin; Dioxanes; Hot Temperature; Idazoxan; Male; Naloxone; Neurokinin A; Neurokinin B; Neuropeptides; Nociceptors; Pain Measurement; Peptide Fragments; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Spinal Cord; Substance P | 1988 |
The effect of peptides on the motility of the stomach, intestine and rectum in the skate (Raja).
Topics: Animals; Bradykinin; Electric Fish; Gastrointestinal Motility; In Vitro Techniques; Intestines; Neurotensin; Pentagastrin; Peptides; Rectum; Skates, Fish; Stomach; Substance P; Tetrodotoxin; Vasoactive Intestinal Peptide | 1988 |
Natriuretic and vasodilating activities of intrarenally administered atriopeptin II, substance P and bradykinin in the dog.
Topics: Animals; Atrial Natriuretic Factor; Bradykinin; Dogs; Female; Hydrochlorothiazide; Kidney; Male; Natriuresis; Regional Blood Flow; Substance P; Time Factors; Vascular Resistance; Vasodilation | 1988 |
Simultaneous release by bradykinin of substance P- and calcitonin gene-related peptide immunoreactivities from capsaicin-sensitive structures in guinea-pig heart.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Guinea Pigs; Heart; In Vitro Techniques; Neuropeptides; Perfusion; Substance P | 1988 |
The bradykinin-induced release of substance P from nerve fibre endings in the rat saphenous nerve neuroma is not related to electrophysiological excitation.
Topics: Animals; Bradykinin; Calcium; Electric Stimulation; In Vitro Techniques; Male; Nerve Endings; Neuroma; Peripheral Nervous System Neoplasms; Rats; Rats, Inbred Strains; Substance P | 1988 |
Chemical factors in the sensitization of cutaneous nociceptors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Bradykinin; Indomethacin; Nociceptors; Prostaglandins E; Pyrazoles; Rabbits; Skin; Substance P | 1988 |
The metabolism of neuropeptides. Hydrolysis of peptides by the phosphoramidon-insensitive rat kidney enzyme 'endopeptidase-2' and by rat microvillar membranes.
Topics: Angiotensins; Animals; Atrial Natriuretic Factor; Bradykinin; Chromatography, High Pressure Liquid; Glycopeptides; Gonadotropin-Releasing Hormone; Hydrolysis; Kidney; Kinetics; Metalloendopeptidases; Microvilli; Neprilysin; Neuropeptides; Rats; Substance P; Swine | 1988 |
Potentiation of IL-1-induced BALB/3T3 fibroblast proliferation by neuropeptides.
Topics: Adjuvants, Immunologic; Animals; Bradykinin; Cell Division; Cell Line; Fibroblasts; Histamine; Interleukin-1; Mice; Mice, Inbred BALB C; Neuropeptides; Peptide Fragments; Serotonin; Substance P | 1988 |
[Effects of inhalation anesthetics on release of substance P during ventriculocisternal and spinal perfusions in rats in vivo].
Topics: Anesthesia, Inhalation; Animals; Bradykinin; Ether; Halothane; Methoxyflurane; Morphine; Nervous System; Rats; Substance P | 1987 |
Release of multiple tachykinins from capsaicin-sensitive sensory nerves in the lung by bradykinin, histamine, dimethylphenyl piperazinium, and vagal nerve stimulation.
Topics: Animals; Bradykinin; Capsaicin; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Female; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Nervous System; Neurokinin A; Pulmonary Artery; Sensation; Substance P; Tachykinins; Trachea; Vagus Nerve | 1988 |
Neither nitric oxide nor nitroglycerin accounts for all the characteristics of endothelially mediated vasodilatation of pig coronary arteries.
Topics: Animals; Arteries; Biological Factors; Bradykinin; Coronary Vessels; In Vitro Techniques; Membrane Potentials; Nitric Oxide; Nitroglycerin; Substance P; Swine; Vasodilation | 1988 |
Alteration of fate of vasoactive autacoids in pulmonary circulation following monocrotaline-induced lung vascular injury in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Autacoids; Blood Pressure; Body Weight; Bradykinin; Dinoprostone; Injections, Subcutaneous; Lung; Lung Diseases; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Substance P; Time Factors | 1988 |
Hemoglobin causes both endothelium-dependent and endothelium-independent contraction of the pig coronary arteries, independently of an inhibition of EDRF effects.
Topics: Animals; Biological Factors; Bradykinin; Coronary Vessels; Cyclooxygenase Inhibitors; Endothelium, Vascular; Hemoglobins; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Membrane Potentials; Methemoglobin; Nitric Oxide; Oxyhemoglobins; Substance P; Swine; Vasoconstriction | 1989 |
Determination of cyclopeptide conformations in solution using NMR data and conformational energy calculations.
Topics: Bradykinin; Magnetic Resonance Spectroscopy; Models, Molecular; Peptides, Cyclic; Protein Conformation; Substance P; Thermodynamics | 1988 |
Effects of neuropeptides and capsaicin on tracheobronchial blood flow of the pig.
Topics: Animals; Bradykinin; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Injections, Intravenous; Neuropeptides; Peptide PHI; Regional Blood Flow; Substance P; Swine; Trachea; Vascular Resistance; Vasoactive Intestinal Peptide | 1989 |
Preincubation of human synovial cells with IL-1 modulates prostaglandin E2 release in response to bradykinin.
Topics: Adjuvants, Immunologic; Bradykinin; Calcimycin; Cells, Cultured; Dinoprost; Dinoprostone; Humans; Interleukin-1; Kinetics; Neurokinin A; Substance P; Synovial Membrane | 1989 |
Bradykinin and substance P potentiate acetylcholine-induced bronchospasm in guinea-pig.
Topics: Acetylcholine; Animals; Bradykinin; Bronchi; Bronchial Spasm; Cyclooxygenase Inhibitors; Drug Synergism; Guinea Pigs; Indomethacin; Male; Parasympathetic Nervous System; Substance P; Vagotomy | 1989 |
A comparison of bradykinin- and capsaicin-induced myocardial and coronary effects in isolated perfused heart of guinea-pig: involvement of substance P and calcitonin gene-related peptide release.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Circulation; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Neuropeptides; Radioimmunoassay; Substance P; Time Factors; Vasodilator Agents | 1989 |
Antisecretory activity of the alpha 2-adrenoceptor agonist, xylazine in rat jejunal epithelium.
Topics: Adrenergic alpha-Agonists; Animals; Bradykinin; Carbachol; Chlorides; Colforsin; Epithelium; In Vitro Techniques; Intestinal Mucosa; Ion Channels; Male; Piroxicam; Rats; Rats, Inbred Strains; Substance P; Thiazines; Vasoactive Intestinal Peptide; Xylazine | 1989 |
Vasodepression ex vivo after administration of inflammatory mediators in vivo in the rat.
Topics: Alprostadil; Animals; Biological Factors; Bradykinin; Endotoxins; Epoprostenol; Escherichia coli; Female; Histamine; Inflammation; Norepinephrine; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Serotonin; SRS-A; Substance P; Vasoconstriction | 1989 |
Endothelium-dependent and -independent responses to vasoactive substances of isolated human coronary arteries.
Topics: Acetylcholine; Adult; Aged; Aged, 80 and over; Aging; Bradykinin; Coronary Vessels; Cyclic GMP; Endothelium, Vascular; Female; Histamine; Humans; In Vitro Techniques; Infant; Male; Middle Aged; Serotonin; Substance P; Vasoconstrictor Agents; Vasodilator Agents | 1989 |
Role of the mediators in pulmonary hyperreactivity: the cocktail interaction hypothesis.
Topics: Acetylcholine; Animals; Bradykinin; Disease Models, Animal; Drug Synergism; Guinea Pigs; Male; Prostaglandins D; Respiratory Hypersensitivity; Substance P | 1989 |
Modified formalin test: characteristic biphasic pain response.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bromelains; Capsaicin; Dexamethasone; Dose-Response Relationship, Drug; Formaldehyde; Indomethacin; Male; Mice; Morphine; Nerve Fibers; p-Methoxy-N-methylphenethylamine; Pain; Pain Measurement; Sciatic Nerve; Substance P; Time Factors | 1989 |
Multiple mechanisms in the motor responses of the guinea-pig isolated urinary bladder to bradykinin.
Topics: Animals; Apamin; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; Indomethacin; Kallidin; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Substance P; Tetrodotoxin; Thiorphan; Urinary Bladder | 1989 |
Modulation of the vasodepressor actions of acetylcholine, bradykinin, substance P and endothelin in the rat by a specific inhibitor of nitric oxide formation.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Bradykinin; Endothelins; Epoprostenol; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Peptides; Rats; Stereoisomerism; Substance P | 1989 |
[Structural features of linear and cyclic analogs of angiotensin, affecting secretion of histamine from rat mast cells].
Topics: Adrenocorticotropic Hormone; Amino Acid Sequence; Angiotensin II; Animals; Bradykinin; Concanavalin A; Histamine Release; Kallidin; Mast Cells; Molecular Sequence Data; Neurotensin; p-Methoxy-N-methylphenethylamine; Peptides, Cyclic; Peritoneal Cavity; Polymyxin B; Protein Conformation; Rats; Substance P | 1989 |
The localization and release of substance P and calcitonin gene-related peptide at nerve fibre endings in rat cutaneous nerve neuroma.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Male; Nerve Endings; Neuroma; Peripheral Nervous System Neoplasms; Rats; Rats, Inbred Strains; Substance P | 1989 |
Comparison of responses to acetylcholine and serotonin on isolated canine and human coronary arteries.
Topics: Acetylcholine; Adolescent; Adult; Animals; Bradykinin; Child; Coronary Vessels; Dinoprost; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Muscle Contraction; Muscle, Smooth, Vascular; Serotonin; Substance P | 1989 |
Differential release of histamine and prostaglandin D2 in rat peritoneal mast cells activated with peptides.
Topics: Animals; Bradykinin; Cells, Cultured; Histamine Release; In Vitro Techniques; Male; Mast Cells; Neuropeptides; Neurotensin; Peritoneal Cavity; Prostaglandin D2; Rats; Substance P | 1989 |
Substance P and bradykinin hyperpolarize pig coronary artery endothelial cells in primary culture.
Topics: Animals; Bradykinin; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; In Vitro Techniques; Membrane Potentials; Potassium; Sodium-Potassium-Exchanging ATPase; Substance P; Swine | 1989 |
Two classes of antagonist interact with receptors for the mitogenic neuropeptides bombesin, bradykinin, and vasopressin.
Topics: Animals; Arginine Vasopressin; Bombesin; Bradykinin; Cells, Cultured; DNA Replication; Fluoroacetates; Gastrin-Releasing Peptide; Mice; Peptides; Protein Binding; Receptors, Angiotensin; Receptors, Bombesin; Receptors, Bradykinin; Receptors, Neurotransmitter; Receptors, Vasopressin; Substance P | 1988 |
Endothelium-dependent vasodilatation in human epicardial coronary arteries: effect of prolonged exposure to glyceryl trinitrate or SIN-1.
Topics: Adult; Analysis of Variance; Bradykinin; Calcimycin; Dinoprost; Drug Tolerance; Humans; In Vitro Techniques; Middle Aged; Molsidomine; Myocardial Contraction; Nitroglycerin; Substance P; Vasodilator Agents | 1989 |
Substance P antagonists showing some selectivity for different receptor types.
Topics: Angiotensin II; Animals; Bradykinin; Cricetinae; Dogs; Guinea Pigs; In Vitro Techniques; Muscle, Smooth; Muscle, Smooth, Vascular; Nerve Tissue Proteins; Neurokinin A; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P | 1985 |
Excitatory neuropeptides activate opioid mechanisms in the guinea pig ileum.
Topics: Angiotensin II; Animals; Bombesin; Bradykinin; Corticotropin-Releasing Hormone; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Nerve Tissue Proteins; Neurotensin; Sincalide; Substance P; Tetragastrin | 1985 |
Release of histamine from mast cells by vasoactive peptides.
Topics: Angiotensin II; Animals; Bradykinin; Eledoisin; Glucagon; Histamine Release; Kallidin; L-Lactate Dehydrogenase; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Peptides; Rats; Substance P; Surface-Active Agents; Trypan Blue | 1973 |
Formation of a factor increasing vascular permeability during electrical stimulation of the saphenous nerve in rats.
Topics: Acetylcholine; Animals; Aspirin; Bradykinin; Capillary Permeability; Carboxypeptidases; Chymotrypsin; Dialysis; Electric Stimulation; Histamine; Indomethacin; Kininogens; Kinins; Leg; Male; Neurons; Perfusion; Prostaglandins; Proteins; Rats; Serotonin; Staining and Labeling; Substance P; Trypsin | 1974 |
The bronchoconstrictor action of the tetradecapeptide bombesin in the guinea-pig.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Bronchi; Ceruletide; Eledoisin; Female; Guinea Pigs; Histamine; Isoproterenol; Male; Muscle, Smooth; Peptides; Prostaglandins; Serotonin; Substance P | 1973 |
The effects of substance P and other peptides on spinal neurons of the frog.
Topics: Angiotensin II; Animals; Bradykinin; Ceruletide; Dose-Response Relationship, Drug; Electrophysiology; Eledoisin; Glutamates; Interneurons; Motor Neurons; Nerve Endings; Neurons; Neurotransmitter Agents; Peptides; Rana catesbeiana; Reflex; Spinal Cord; Spinal Nerve Roots; Stimulation, Chemical; Substance P; Synaptic Transmission | 1974 |
Release of a bradykinin-like substance of nervous stimulation of a frog stomach muscle preparation.
Topics: Animals; Anura; Aspirin; Bradykinin; Intestine, Small; Muscle Contraction; Muscle, Smooth; Peptides; Rabbits; Stomach; Substance P; Vagus Nerve | 1967 |
Quantitative study of P substance in the megaesophagus and megacolon of human Trypanosoma cruzi infections.
Topics: Adult; Aged; Animals; Biological Assay; Bradykinin; Chagas Disease; Child, Preschool; Colon; Duodenum; Esophageal Achalasia; Esophagus; Female; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Megacolon; Middle Aged; Muscle Contraction; Rats; Substance P; Trypanosoma cruzi | 1973 |
[Crossed tachyphylaxis of peptides].
Topics: Animals; Bradykinin; Eledoisin; Guinea Pigs; Ileum; In Vitro Techniques; Kallidin; Muscle, Smooth; Peptides; Substance P; Tachyphylaxis | 1967 |
[Peptide receptors for tachykinins in the human Fallopian tube].
Topics: Acetylcholine; Adolescent; Adult; Aged; Animals; Bradykinin; Cats; Eledoisin; Fallopian Tubes; Female; Guinea Pigs; Histamine; Humans; Ileum; In Vitro Techniques; Kinins; Middle Aged; Muscle, Smooth; Ovulation; Peptides; Physiology, Comparative; Prostaglandins; Rabbits; Rats; Receptors, Drug; Serotonin; Sheep; Stimulation, Chemical; Substance P | 1969 |
Proceedings: Influence of prostaglandin E1, indomethacin, calcium and potassium on the action of nociceptive substances.
Topics: Acetylcholine; Animals; Atropine; Autonomic Agents; Blood Pressure; Bradykinin; Calcium; Drug Synergism; Ear; Hexamethonium Compounds; Histamine; Indomethacin; Isoproterenol; Nitrites; Papaverine; Perfusion; Potassium; Prostaglandins; Rabbits; Serotonin; Substance P | 1974 |
Interaction of prostaglandins and indomethacin with algesic substances.
Topics: Acetylcholine; Analgesics; Animals; Blood Pressure; Bradykinin; Drug Interactions; Ear; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Muscle Contraction; Perfusion; Prostaglandins; Rabbits; Regional Blood Flow; Serotonin; Serotonin Antagonists; Substance P | 1974 |
The relation between ionic fluxes and the action of drugs on smooth muscle.
Topics: Angiotensin II; Animals; Anura; Bradykinin; Calcium; Histamine; In Vitro Techniques; Kallidin; Muscle Contraction; Muscle, Smooth; Peptides; Stomach; Substance P | 1964 |
The action of physalaemin on the systemic arterial blood pressure of some experimental animals.
Topics: Angiotensin II; Animals; Atropine; Blood Pressure; Bradykinin; Catecholamines; Cats; Chlorpromazine; Dogs; Electrocardiography; Eledoisin; Histamine; In Vitro Techniques; Peptides; Poultry; Rabbits; Rats; Substance P; Sympatholytics | 1965 |
Further studies on the actions of peptides on the superior cervical ganglion and suprarenal medulla.
Topics: Adrenal Medulla; Angiotensin II; Animals; Bradykinin; Cats; Eledoisin; Female; Ganglia, Autonomic; Histamine; Male; Morphine; Nicotine; Oxytocin; Peptides; Serotonin; Substance P; Sympathetic Nervous System; Vasopressins | 1966 |
Potentiation by smooth muscle stimulants of the hypogastric nerve--vas deferens preparation from normal and castrated guinea-pigs.
Topics: Acetylcholine; Amines; Angiotensin II; Animals; Atropine; Barium; Bradykinin; Castration; Electric Stimulation; Epinephrine; Guinea Pigs; Histamine; Hypogastric Plexus; Lysergic Acid Diethylamide; Male; Muscle Contraction; Norepinephrine; Oxytocin; Phenethylamines; Phentolamine; Prostaglandins; Serotonin; Substance P; Vas Deferens; Vasopressins | 1968 |
[Antipyretics, analgesics and plasmakinins].
Topics: Analgesics; Angiotensin II; Bradykinin; Humans; Kallidin; Kinins; Pain; Peptides; Substance P | 1970 |
The action of polypeptides, amines and prostaglandins on isolated smooth muscle preparations of seminal vesicles and deferent ducts.
Topics: Acetylcholine; Amines; Angiotensin II; Animals; Anura; Bradykinin; Ceruletide; Cricetinae; Eledoisin; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Oxytocin; Peptides; Prostaglandins; Rats; Seminal Vesicles; Serotonin; Substance P; Vas Deferens; Vasopressins | 1973 |
Excitation of cerebral cortical neurons by various polypeptides.
Topics: Acetylcholine; Angiotensin II; Animals; Atropine; Bradykinin; Cerebral Cortex; Eledoisin; Male; Peptides; Rats; Stimulation, Chemical; Substance P; Synaptic Transmission | 1974 |
Substance P excitation of cerebral cortical Betz cells.
Topics: Acetylcholine; Animals; Atropine; Bradykinin; Cerebral Cortex; Evoked Potentials; Glutamates; Neurons; Rats; Refractory Period, Electrophysiological; Substance P | 1974 |
The presence of bradykinin-like polypeptides, kinin-releasing and destroying activity in brain.
Topics: Amino Acids; Animals; Anura; Bradykinin; Brain Chemistry; Cattle; Cytoplasmic Granules; Electrophoresis; Esterases; Kinins; Microsomes; Muscle, Smooth; Peptides; Rabbits; Substance P | 1968 |
Influence of morphine, methadone and methadone isomers on some effects of smooth muscle stimulants.
Topics: Acetylcholine; Animals; Barium; Bradykinin; Capillary Permeability; Depression, Chemical; Female; Guinea Pigs; Ileum; Isomerism; Methadone; Morphine; Muscle Contraction; Muscle, Smooth; Rats; Serotonin Antagonists; Stereoisomerism; Structure-Activity Relationship; Substance P; Uterus | 1970 |
Pupillary constriction by bradykinin and capsaicin: mode of action.
Topics: Animals; Bradykinin; Capsaicin; Female; In Vitro Techniques; Male; Miotics; Muscle Contraction; Pupil; Rabbits; Substance P; Tetrodotoxin | 1984 |
Cell culture as models for studying neural functions.
Topics: Animals; Animals, Newborn; Bradykinin; Cell Membrane Permeability; Cells, Cultured; Clone Cells; Cyclic AMP; Glioma; Hybrid Cells; Mice; Nervous System Physiological Phenomena; Neuroblastoma; Neurotransmitter Agents; Rats; Sodium-Potassium-Exchanging ATPase; Substance P; Taurine | 1984 |
Field-stimulus response of guinea-pig atria as influenced by the peptides angiotensin, bradykinin, and substance P.
Topics: Angiotensin II; Animals; Bradykinin; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Lidocaine; Male; Pindolol; Substance P; Tetrodotoxin; Vas Deferens | 1980 |
The effects of sensory denervation on the responses of the rabbit eye to prostaglandin E1, bradykinin and substance P.
Topics: Animals; Bradykinin; Capsaicin; Denervation; Eye; Intraocular Pressure; Male; Prostaglandins E; Rabbits; Sensory Deprivation; Substance P | 1980 |
Identification and characterization of the high affinity vascular angiotensin II receptor in rat mesenteric artery.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Bradykinin; Calcium; Edetic Acid; Egtazic Acid; Iodine Radioisotopes; Kinetics; Magnesium; Male; Manganese; Mesenteric Arteries; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Substance P | 1980 |
Responses of spinal neurones to a substance P analogue, noxious pinch and bradykinin.
Topics: Animals; Bradykinin; Male; Neurons; Nociceptors; Rats; Spinal Nerves; Substance P | 1980 |
Nociceptor stimulation and PGE release by capsaicin.
Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Calcium; Capsaicin; Ear; Fatty Acids, Unsaturated; Injections, Intra-Arterial; Nociceptors; Prostaglandins; Prostaglandins E; Rabbits; Substance P | 1980 |
Brain peptides as neurotransmitters.
Topics: Angiotensins; Animals; Bradykinin; Brain; Carnosine; Cholecystokinin; Endorphins; Gastrins; Glucagon; Humans; Insulin; Nerve Tissue Proteins; Neurotensin; Peptides; Pituitary Hormone-Releasing Hormones; Receptors, Opioid; Substance P; Vasoactive Intestinal Peptide; Vasopressins | 1980 |
[Hemodynamic characteristics of polypeptide substance P compared to bradykinin and prostaglandin E1].
Topics: Animals; Biotransformation; Blood Pressure; Bradykinin; Lung; Prostaglandins E; Rabbits; Rats; Substance P | 1980 |
Effect of some vasoactive peptides on the lower esophageal sphincter.
Topics: Angiotensin II; Animals; Bradykinin; Esophagogastric Junction; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurotensin; Peptides; Rats; Substance P; Vasopressins | 1980 |
Screening for rabbit brain neuropeptide-metabolizing peptidases. Inhibition of endopeptidase B by bradykinin potentiating peptide 9a (SQ 20881).
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Brain; Gonadotropin-Releasing Hormone; Isoenzymes; Kinetics; Neurotensin; Oligopeptides; Rabbits; Substance P; Substrate Specificity; Teprotide | 1980 |
Effects of vasoactive polypeptides on the uterine vasculature.
Topics: Animals; Blood Pressure; Bradykinin; Epoprostenol; Estradiol; Female; Gastrointestinal Hormones; Heart Rate; Neurotensin; Sheep; Substance P; Uterine Contraction; Uterus; Vasoactive Intestinal Peptide; Vasodilation | 1981 |
[Pharmacology of thin pain fibers].
Topics: Animals; Bradykinin; Capsaicin; Nerve Fibers; Nociceptors; Rabbits; Substance P; Synaptic Transmission | 1980 |
The lung in relation to vasoactive polypeptides.
Topics: Animals; Bombesin; Bradykinin; Gastrointestinal Hormones; Humans; Lung; Lung Neoplasms; Muscle, Smooth; Peptides; Peptidyl-Dipeptidase A; Substance P; Vasoactive Intestinal Peptide | 1980 |
Failure of peptides (angiotensin, bradykinin, substance P, physalaemin, Met-enkephalin) to influence the cardiac action potential.
Topics: Action Potentials; Angiotensin II; Animals; Bradykinin; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Heart; Male; Papillary Muscles; Peptides; Physalaemin; Substance P | 1980 |
Inhibition by bradykinin of the vascular action of angiotensin II in the dog kidney.
Topics: Angiotensin II; Animals; Bradykinin; Dogs; Epoprostenol; Kidney; Male; Meclofenamic Acid; Prostaglandins E; Regional Blood Flow; Substance P; Vasoconstriction | 1981 |
The contractile effect of bombesin on the rat isolated urinary bladder.
Topics: Animals; Bombesin; Bradykinin; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Muscle Contraction; Peptides; Rats; Substance P; Urinary Bladder | 1981 |
Neurotensin-induced contractions in venous smooth muscle.
Topics: Angiotensin II; Animals; Bradykinin; Dose-Response Relationship, Drug; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neurotensin; Norepinephrine; Portal Vein; Rats; Substance P | 1980 |
Enkephalins, substance P, bradykinin and angiotensin II: differential sites of action on the hypothalamo-neurohypophysial system.
Topics: Action Potentials; Angiotensin II; Animals; Bradykinin; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Enkephalin, Leucine; Enkephalins; Female; Hormones; Hypothalamo-Hypophyseal System; Male; Rats; Substance P | 1981 |
Pharmacological characterization of the vascular permeability enhancing effects of kinins in the rabbit skin.
Topics: Animals; Bombesin; Bradykinin; Capillary Permeability; Cholecystokinin; Coloring Agents; Female; Kinins; Male; Peptide Fragments; Rabbits; Sincalide; Skin; Substance P | 1981 |
Pharmacological comparison of bPTH-(1-34) and other hypotensive peptides in the dog.
Topics: Adrenocorticotropic Hormone; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Dogs; Eledoisin; Female; Male; Neurotensin; Oligopeptides; Parathyroid Hormone; Peptide Fragments; Peptides; Substance P; Time Factors; Vasoactive Intestinal Peptide; Xenopus Proteins | 1980 |
Algesiogenic and analgesic activities of synthetic substance P.
Topics: Analgesics; Animals; Bradykinin; Brain Chemistry; Dose-Response Relationship, Drug; Endorphins; Female; Histamine Release; Humans; Male; Mice; Pain; Rabbits; Rats; Rats, Inbred Strains; Substance P | 1981 |
A comparison of the miotic and inflammatory effects of biologically active polypeptides and prostaglandin E2 on the rabbit eye.
Topics: Animals; Bradykinin; Eledoisin; Eye; Inflammation; Intraocular Pressure; Miotics; Peptide Fragments; Peptides; Pituitary Hormones, Posterior; Prostaglandins E; Rabbits; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1982 |
The effects of neuropeptides on discrete-trial conditioned avoidance responding.
Topics: Animals; Avoidance Learning; beta-Endorphin; Bombesin; Bradykinin; Dose-Response Relationship, Drug; Endorphins; Gonadotropin-Releasing Hormone; Male; Melanocyte-Stimulating Hormones; Neurotensin; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Substance P; Thyrotropin-Releasing Hormone | 1982 |
Sensory neural mechanisms in contraction of the isolated sphincter pupillae: the role for substance P and the effects of sensory denervation on the responses to miotics.
Topics: Animals; Bradykinin; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Iris; Male; Miotics; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Rabbits; Substance P; Trigeminal Nerve | 1982 |
Effects of substance P-(1-9) nonapeptide amide on inactivation of substance P in vitro.
Topics: Acetylcholine; Animals; Bradykinin; Female; Guinea Pigs; Ileum; In Vitro Techniques; Muscle, Smooth; Peptide Fragments; Substance P; Urinary Bladder | 1982 |
Trigeminal nerve: the possible origin of substance p-nergic response in isolated rabbit iris sphincter muscle.
Topics: Animals; Bradykinin; Capsaicin; Carbachol; Electric Stimulation; Enkephalins; Female; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscles; Rabbits; Somatostatin; Substance P; Trigeminal Nerve; Vasoactive Intestinal Peptide | 1982 |
Hydrolysis of substance P and bradykinin by black widow spider venom gland extract.
Topics: Animals; Arthropod Venoms; Black Widow Spider; Bradykinin; Exocrine Glands; Guinea Pigs; Hydrolysis; In Vitro Techniques; Isoflurophate; Male; Protease Inhibitors; Proteins; Spider Venoms; Substance P; Time Factors; Tissue Extracts | 1982 |
Some rat sensory neurons in culture express characteristics of differentiated pain sensory cells.
Topics: Animals; Animals, Newborn; Bradykinin; Capsaicin; Cell Differentiation; Cells, Cultured; Dinoprostone; Ganglia, Spinal; Neurons; Pain; Prostaglandins E; Rats; Substance P; Trigeminal Nerve | 1983 |
Pharmacological observations of plasminogen activator release caused by vasoactive agents in isolated perfused pig ears.
Topics: Animals; Bradykinin; Calcium-Binding Proteins; Catecholamines; Dilazep; Dogs; Dose-Response Relationship, Drug; Ear, External; Guinea Pigs; In Vitro Techniques; Perfusion; Plasminogen Activators; Rabbits; Rats; Serotonin; Substance P; Swine; Thrombin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 1983 |
Non-cholinergic, non-adrenergic inhibitory neurons in human internal anal sphincter muscle.
Topics: Anal Canal; Bradykinin; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Morphine; Muscle Contraction; Neural Inhibition; Substance P; Vasoactive Intestinal Peptide | 1983 |
The role of the kallikrein/kinin system in the excretion of water in dogs.
Topics: Acetylcholine; Angiotensin II; Animals; Bradykinin; Diuresis; Dogs; Dopamine; Isoproterenol; Kallikreins; Kinins; Norepinephrine; Prostaglandins E; Substance P; Vasodilator Agents | 1983 |
Evaluation of the contribution of mast cell mediators to the hypotensive activity of various peptides in rats.
Topics: Animals; Blood Pressure; Bradykinin; Dexamethasone; Gastrointestinal Hormones; Hematocrit; Histamine Release; Male; Mast Cells; Rats; Rats, Inbred Strains; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1983 |
Purification and inhibition by neuropeptides of angiotensin-converting enzyme from rat brain.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Brain; Enkephalin, Leucine; Enkephalin, Methionine; Kinetics; Nerve Tissue Proteins; Papain; Peptidyl-Dipeptidase A; Rats; Solubility; Substance P | 1983 |
Neural actions of several substance P antagonists in the rat spinal cord.
Topics: Animals; Bradykinin; Evoked Potentials; Female; Hypothalamo-Hypophyseal System; Neurons; Nociceptors; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Synaptic Transmission | 1983 |
Bradykinin contracts the pupillary sphincter and evokes ocular inflammation through release of neuronal substance P.
Topics: Animals; Atropine; Bradykinin; Eye; In Vitro Techniques; Inflammation; Neurons; Pupil; Rabbits; Substance P; Tetrodotoxin; Time Factors | 1983 |
Response of urethral smooth muscles to pharmacological agents. II. Noncholinergic, nonadrenergic agonists and antagonists.
Topics: Animals; Autonomic Agents; Bradykinin; Cats; Dinoprost; Dinoprostone; Female; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins E; Prostaglandins F; Substance P; Urethra | 1983 |
A specific substance P antagonist attenuates non-cholinergic electrically induced contractures of the guinea pig isolated ileum.
Topics: Animals; Bradykinin; Dinoprost; Dose-Response Relationship, Drug; Drug Interactions; Gastrointestinal Motility; Guinea Pigs; Histamine; In Vitro Techniques; Prostaglandins F; Serotonin; Substance P | 1983 |
Vasodilatation by acetylcholine is endothelium-dependent: a study by sonomicrometry in canine femoral artery in vivo.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Blood Pressure; Bradykinin; Dogs; Endothelium; Female; Femoral Artery; Male; Sonication; Substance P; Vasodilation | 1983 |
Vascular protein linkage in various tissue induced by substance P, capsaicin, bradykinin, serotonin, histamine and by antigen challenge.
Topics: Animals; Antigens; Blood Proteins; Bradykinin; Capillary Permeability; Capsaicin; Guinea Pigs; Histamine; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Substance P | 1983 |
[Effects of bradykinin and capsaicin on substance P-induced reactions in the iris sphincter muscle].
Topics: Animals; Bradykinin; Capsaicin; Electric Stimulation; In Vitro Techniques; Iris; Muscle Contraction; Rabbits; Substance P | 1983 |
Spinal substance P transmits bradykinin but not osmotic stimuli from hepatic portal vein to hypothalamus in rat.
Topics: Animals; Bradykinin; Female; Hypothalamo-Hypophyseal System; Nociceptors; Pain; Portal Vein; Rats; Receptors, Cell Surface; Spinal Cord; Substance P; Synaptic Transmission; Water-Electrolyte Balance | 1984 |
Peptides and histamine release.
Topics: Acetylcholine; Bradykinin; Gastrins; Histamine Release; Humans; Hypersensitivity, Delayed; Injections, Subcutaneous; Mast Cells; Neurons; Peptides; Structure-Activity Relationship; Substance P; Synaptic Transmission | 1984 |
Capsaicin and bradykinin-induced substance P-ergic responses in the iris sphincter muscle of the rabbit.
Topics: Animals; Atropine; Bradykinin; Capsaicin; Carbachol; Electric Stimulation; Female; Guanethidine; Iris; Male; Muscle Contraction; Rabbits; Substance P; Tachyphylaxis | 1984 |
Enhancement of the permeability-increasing effect of bradykinin and substance P by a peptide derived from fibrinogen.
Topics: Animals; Bradykinin; Capillary Permeability; Drug Synergism; Fibrin Fibrinogen Degradation Products; Histamine; Male; Microcirculation; Rats; Rats, Inbred Strains; Serum Albumin, Radio-Iodinated; Skin; Substance P; Tuftsin | 1983 |
Fibrin-derived vasoactive peptides release histamine.
Topics: Animals; Bradykinin; Capillary Permeability; Fibrin Fibrinogen Degradation Products; Histamine H1 Antagonists; Histamine Release; Humans; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Pyrilamine; Rats; Skin; Substance P | 1983 |
Peptides and nociception.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Bombesin; Bradykinin; Cholecystokinin; Dynorphins; Endorphins; Enkephalins; Melanocyte-Stimulating Hormones; Mice; Nervous System; Neurotensin; Pain; Peptide Fragments; Peptides; Rats; Somatostatin; Substance P; Thyrotropin-Releasing Hormone; Vasopressins | 1984 |
[Pathophysiology of pain].
Topics: Bradykinin; Delta Sleep-Inducing Peptide; Dopamine; Endorphins; Humans; Models, Theoretical; Nociceptors; Oligopeptides; Pain; Prostaglandins; Serotonin; Stress, Psychological; Substance P | 1984 |
[A direct central action of bradykinin (1)].
Topics: Animals; Bradykinin; Cats; Dogs; Eledoisin; Guinea Pigs; Humans; Kallidin; Kallikreins; Rabbits; Rats; Substance P; Trypsin | 1984 |
Fragmentation reactions of multiply-protonated peptides and implications for sequencing by tandem mass spectrometry with low-energy collision-induced dissociation.
Topics: Amino Acid Sequence; Angiotensin I; Bradykinin; Endorphins; gamma-Endorphin; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Peptides; Protons; Sequence Analysis; Substance P; Vasoactive Intestinal Peptide | 1993 |
Nitric oxide release from porcine mitral valves.
Topics: Adenosine Diphosphate; Amino Acid Oxidoreductases; Animals; Arginine; Biological Assay; Bradykinin; Calcimycin; Calcium; Culture Techniques; Endocardium; Endothelium; Epithelium; Mitral Valve; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Substance P; Swine; Thrombin | 1993 |
Modulation of nonadrenergic noncholinergic neural bronchoconstriction by bradykinin in anesthetized guinea pigs in vivo.
Topics: Animals; Bradykinin; Bronchoconstriction; Guinea Pigs; Male; Receptors, Adrenergic; Receptors, Cholinergic; Substance P | 1994 |
Cardiovascular effects of intrathecally administered bradykinin in the rat: characterization of receptors with antagonists.
Topics: Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Heart Rate; Injections, Spinal; Male; Rats; Rats, Wistar; Receptors, Bradykinin; Spinal Cord; Substance P | 1993 |
Anti-edema action of formoterol in rat trachea does not depend on capsaicin-sensitive sensory nerves.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Afferent Pathways; Animals; Bradykinin; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Endothelium, Vascular; Ethanolamines; Formoterol Fumarate; Injections, Intravenous; Male; Platelet Activating Factor; Premedication; Rats; Rats, Inbred F344; Substance P; Trachea; Tracheal Diseases | 1994 |
Palmitoyl-L-carnitine modifies the function of vascular endothelium.
Topics: Acetylcholine; Animals; Aorta; Bradykinin; Calcium; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Fura-2; Myocardial Ischemia; Palmitoylcarnitine; Rabbits; Signal Transduction; Substance P; Vasodilation | 1994 |
Bradykinin-induced airway inflammation. Contribution of sensory neuropeptides differs according to airway site.
Topics: Animals; Asthma; Atropine; Bradykinin; Capillary Permeability; Dipeptides; Evans Blue; Guinea Pigs; Indoles; Indomethacin; Inflammation; Male; Neurons, Afferent; Premedication; Propranolol; Substance P; Tachykinins | 1994 |
Subpopulations of neonatal rat sensory neurons express functional neurotransmitter receptors which elevate intracellular calcium.
Topics: Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Bradykinin; Calcium; Capsaicin; Cell Size; Classification; Ganglia, Spinal; Intracellular Fluid; Neurons, Afferent; Rats; Receptors, Neurotransmitter; Substance P | 1994 |
Properties of putative cardiac and non-cardiac neurones in the rat stellate ganglion.
Topics: Action Potentials; Angiotensin II; Animals; Axons; Bradykinin; Electric Stimulation; Female; Heart; Histocytochemistry; Male; Membrane Potentials; Neural Pathways; Neurons; Norepinephrine; Parasympathomimetics; Pons; Rats; Rats, Wistar; Serotonin; Stellate Ganglion; Substance P; Synapses | 1994 |
A vascular smooth muscles nitric oxide relaxation by a mechanism distinct of calcium changes.
Topics: Acetylcholine; Animals; Arginine; Bradykinin; Calcimycin; Calcium; Coronary Vessels; Cytosol; Dinoprost; Egtazic Acid; Endothelium, Vascular; Fura-2; In Vitro Techniques; Indomethacin; Ionomycin; Isometric Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroglycerin; Potassium; Spectrometry, Fluorescence; Substance P; Swine | 1994 |
Effects of neuropeptide analogues on calcium flux and proliferation in lung cancer cell lines.
Topics: Amino Acid Sequence; Bombesin; Bradykinin; Calcium; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cholecystokinin; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Molecular Sequence Data; Neuropeptides; Peptides; Substance P; Tumor Cells, Cultured | 1994 |
Comparative effects of N omega-nitro-L-arginine and N omega-nitro-L-arginine methyl ester on vasodilator responses to acetylcholine, bradykinin, and substance P.
Topics: Acetylcholine; Animals; Arginine; Bradykinin; Cats; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Splanchnic Circulation; Substance P; Vasodilator Agents | 1994 |
Glucocorticoids do not alter peptidase expression on a human bronchial epithelial cell line.
Topics: Aminopeptidases; Bradykinin; Bronchi; Budesonide; CD13 Antigens; Cell Line, Transformed; Enkephalins; Epithelium; Flow Cytometry; Glucocorticoids; Humans; Kallidin; Neprilysin; Pregnenediones; Substance P; Substrate Specificity | 1994 |
Mast cells in experimental allergic encephalomyelitis: characterization, distribution in the CNS and in vitro activation by myelin basic protein and neuropeptides.
Topics: Animals; beta-N-Acetylhexosaminidases; Bradykinin; Central Nervous System; Cytoplasmic Granules; Encephalomyelitis, Autoimmune, Experimental; Female; Mast Cells; Myelin Basic Protein; Neuroimmunomodulation; Neuropeptides; Peritoneal Cavity; Rats; Rats, Inbred Lew; Substance P; Thalamus | 1994 |
Comparative effects of L-NNA and alkyl esters of L-NNA on pulmonary vasodilator responses to ACh, BK, and SP.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Bradykinin; Cats; Female; Heart Rate; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Pulmonary Circulation; Substance P; Vasodilation; Vasodilator Agents | 1994 |
Ventricular arrhythmias induced by chemically modified intrinsic cardiac neurones.
Topics: Adenosine; Adenosine Triphosphate; Angiotensin II; Animals; Arrhythmias, Cardiac; Autonomic Agents; Bethanechol; Bethanechol Compounds; Bradykinin; Dogs; Female; Glutamates; Heart; Isoproterenol; Male; Myocardial Contraction; Neurons; Nicotine; Peptides; Purines; Substance P; Vasoactive Intestinal Peptide | 1994 |
Influence of arterial diameter on vasomotor responses in the porcine coronary vasculature.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arteries; Bradykinin; Coronary Circulation; Female; In Vitro Techniques; Male; Norepinephrine; Propranolol; Prostaglandin Endoperoxides, Synthetic; Substance P; Swine; Swine, Miniature; Thromboxane A2; Vasomotor System | 1994 |
Tachykinin induced regulation of excitatory amino acid responses in the rat spinal cord in vitro.
Topics: Alkaloids; Animals; Animals, Newborn; Bradykinin; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; In Vitro Techniques; Kinetics; N-Methylaspartate; Neurokinin A; Protease Inhibitors; Protein Kinase C; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Staurosporine; Substance P; Time Factors | 1994 |
Prostaglandin E2 enhances bradykinin-stimulated release of neuropeptides from rat sensory neurons in culture.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Cells, Cultured; Chromatography, High Pressure Liquid; Dinoprostone; Drug Synergism; Female; Ganglia, Spinal; Indomethacin; Neurons, Afferent; Pregnancy; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Substance P | 1994 |
Human basilar and middle cerebral arteries exhibit endothelium-dependent responses to peptides.
Topics: Adult; Aged; Basilar Artery; Bradykinin; Cerebral Arteries; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Substance P; Vasodilation; Vasopressins | 1994 |
An endo-acting proline-specific oligopeptidase from Treponema denticola ATCC 35405: evidence of hydrolysis of human bioactive peptides.
Topics: Amino Acid Sequence; Amino Acids; Angiotensin II; Bradykinin; Chelating Agents; Enzyme Activation; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Molecular Weight; Oligopeptides; Prolyl Oligopeptidases; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Sodium Chloride; Structure-Activity Relationship; Substance P; Substrate Specificity; Sulfhydryl Compounds; Temperature; Treponema; Vasopressins | 1994 |
Effect of a neurokinin-1 (NK1) receptor antagonist on oedema formation induced by tachykinins, carrageenin and an allergic response in guinea-pig skin.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Carrageenan; Edema; Guinea Pigs; Indoles; Inflammation; Injections, Intradermal; Isoindoles; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Pyrilamine; Skin; Substance P; Tachykinins | 1994 |
Endothelium-derived relaxing factor and cyclic GMP-dependent vasorelaxation in human chorionic plate arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Arteries; Bradykinin; Calcimycin; Chorion; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Female; Histamine; Humans; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Pregnancy; Prostaglandin Endoperoxides, Synthetic; Serotonin; Substance P; Thromboxane A2; Vasoconstrictor Agents; Vasodilation | 1994 |
Rearrangements of doubly charged acylium ions from lysyl and ornithyl peptides.
Topics: Acetylation; Amino Acid Sequence; Bradykinin; Lysine; Mass Spectrometry; Molecular Sequence Data; Ornithine; Peptides; Peptides, Cyclic; Substance P | 1994 |
Responsiveness of in situ canine nodose ganglion afferent neurones to epicardial mechanical or chemical stimuli.
Topics: Adenosine; Adenosine Triphosphate; Animals; Bradykinin; Constriction; Coronary Vessels; Dogs; Female; Male; Mechanoreceptors; Neural Pathways; Neurons, Afferent; Nodose Ganglion; Pericardium; Substance P | 1994 |
Bradykinin-responsive cells of dorsal root ganglia in culture: cell size, firing, cytosolic calcium, and substance P.
Topics: Animals; Bradykinin; Calcium; Cells, Cultured; Cytosol; Electrophysiology; Fura-2; Ganglia, Spinal; Immunohistochemistry; Kinetics; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Spectrometry, Fluorescence; Substance P | 1994 |
Inhibition of neutrophil and eosinophil adhesion to venules of rat trachea by beta 2-adrenergic agonist formoterol.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Bradykinin; Cell Adhesion; Eosinophils; Ethanolamines; Formoterol Fumarate; Leukocyte Count; Male; Neutrophils; Platelet Activating Factor; Propanolamines; Rats; Rats, Inbred F344; Regional Blood Flow; Substance P; Trachea; Venules | 1994 |
[Releases of bradykinin and substance P by heating hind paw of rat].
Topics: Animals; Bradykinin; Deficiency Diseases; Female; Hot Temperature; Kininogens; Male; Perfusion; Rats; Rats, Inbred BN; Substance P | 1994 |
Modulation of left ventricular relaxation in isolated ejecting heart by endogenous nitric oxide.
Topics: Animals; Bradykinin; Coronary Circulation; Diastole; Guinea Pigs; Heart; Heart Rate; Hemoglobins; In Vitro Techniques; Myocardial Contraction; Nitric Oxide; Nitroprusside; Papillary Muscles; Stroke Volume; Substance P; Time Factors; Ventricular Function, Left | 1994 |
Thrombin receptor-mediated vascular relaxation differentiated by a receptor antagonist and desensitization.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amino Acid Sequence; Animals; Bradykinin; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Kinetics; Molecular Sequence Data; Muscle Relaxation; Muscle, Smooth, Vascular; Oligopeptides; Peptide Fragments; Prostaglandin Endoperoxides, Synthetic; Receptors, Thrombin; Serotonin; Substance P; Swine; Thrombin; Thromboxane A2; Vasoconstrictor Agents | 1994 |
Tachykinins and kinins in antigen-evoked plasma extravasation in guinea-pig nasal mucosa.
Topics: Animals; Biphenyl Compounds; Bradykinin; Capillary Permeability; Capsaicin; Evans Blue; Glycopeptides; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Kinins; Male; Nasal Mucosa; Nerve Endings; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Ovalbumin; Protease Inhibitors; Substance P; Tachykinins | 1994 |
Galanin contracts and relaxes guinea pig and canine intestinal smooth muscle cells through distinct receptors.
Topics: Animals; Bradykinin; Dogs; Galanin; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neuropeptides; Osmolar Concentration; Peptide Fragments; Peptides; Potassium Chloride; Receptors, Galanin; Receptors, Gastrointestinal Hormone; Sincalide; Substance P | 1995 |
Prostacyclin enhances the evoked-release of substance P and calcitonin gene-related peptide from rat sensory neurons.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Cells, Cultured; Dinoprost; Drug Synergism; Epoprostenol; Evoked Potentials; Female; Neurons, Afferent; Potassium; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Substance P | 1994 |
The phosphatase inhibitor, okadaic acid, increases peptide release from rat sensory neurons in culture.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Embryo, Mammalian; Ethers, Cyclic; Ganglia, Spinal; Neurons, Afferent; Okadaic Acid; Phosphoprotein Phosphatases; Potassium Chloride; Rats; Substance P | 1994 |
Spinal antinociception by morphine in rats is antagonised by galanin receptor antagonists.
Topics: Animals; Binding Sites; Bradykinin; Galanin; Injections, Spinal; Male; Morphine; Pain; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Galanin; Receptors, Gastrointestinal Hormone; Spinal Cord; Substance P; Synaptic Membranes | 1994 |
Complement-mediated loss of endothelium-dependent relaxation of porcine coronary arteries. Role of the terminal membrane attack complex.
Topics: Animals; Bradykinin; Complement Activation; Complement Membrane Attack Complex; Complement Pathway, Alternative; Coronary Vessels; Endothelium, Vascular; Humans; Immunohistochemistry; In Vitro Techniques; Myocardial Ischemia; Myocardial Reperfusion; Nitric Oxide; Receptors, Complement; Substance P; Swine; Vasodilation; Zymosan | 1995 |
Substance P and bradykinin are natural inhibitors of CD13/aminopeptidase N.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Bradykinin; CD13 Antigens; Cell Line; Cell Membrane; Endorphins; Enkephalin, Leucine; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; Protease Inhibitors; Substance P; Swine; Tyrosine | 1995 |
Inhibition of hind-paw edema and cutaneous vascular plasma extravasation in mice by acetylshikonin.
Topics: Adrenalectomy; Animals; Anthraquinones; Bradykinin; Capillary Permeability; Cell Degranulation; Dexamethasone; Diphenhydramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Edema; Glucuronidase; Glycogen; Hindlimb; Histamine; Indomethacin; Liver; Mast Cells; Methysergide; Mice; p-Methoxy-N-methylphenethylamine; Polymyxin B; Substance P | 1995 |
Contribution of bradykinin to heat-induced substance P release in the hind instep of rats.
Topics: Animals; Bradykinin; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Hindlimb; Hot Temperature; Kininogens; Nerve Endings; Neurons, Afferent; Perfusion; Rats; Rats, Inbred BN; Substance P | 1995 |
An investigation into the mechanism of capsaicin-induced oedema in rabbit skin.
Topics: Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Catalase; Dexamethasone; Drug Interactions; Edema; Histamine; Indoles; Indomethacin; Injections, Intradermal; Injections, Intravenous; Isoindoles; Male; Piperidines; Rabbits; Regional Blood Flow; Ruthenium Red; Skin; Substance P; Vasodilator Agents | 1995 |
Pharmacological analysis of the local and reflex responses to bradykinin on rat urinary bladder motility in vivo.
Topics: Adrenergic beta-Antagonists; Animals; Bradykinin; Capsaicin; Dose-Response Relationship, Drug; Indoles; Indomethacin; Injections, Spinal; Isoindoles; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Quinuclidines; Rats; Rats, Wistar; Reflex; Substance P; Urinary Bladder | 1995 |
Sequence-specific fragmentation generated by matrix-assisted laser desorption/ionization in a quadrupole ion trap/reflectron time-of-flight device.
Topics: Amino Acid Sequence; Angiotensin III; Bradykinin; Enkephalin, Leucine; Ions; Lasers; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Substance P; Time Factors | 1995 |
Degradation of kinins, angiotensins and substance P by polymorphonuclear matrix metalloproteinases MMP 8 and MMP 9.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensins; Bradykinin; Chromatography, High Pressure Liquid; Collagenases; Hydrolysis; Kinetics; Kinins; Matrix Metalloproteinase 8; Matrix Metalloproteinase 9; Molecular Sequence Data; Peptide Fragments; Substance P; Substrate Specificity; Time Factors | 1994 |
Involvement of the kallikrein-kinin system in the salivary secretion elicited in rats by heat stress.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arginine; Atropine; Bradykinin; Hot Temperature; Kallikrein-Kinin System; Kallikreins; Kininogens; Male; Nitroarginine; Pilocarpine; Rats; Rats, Inbred BN; Rats, Wistar; Saliva; Stress, Physiological; Submandibular Gland; Substance P | 1994 |
Ca2+ signaling through secretagogue and growth factor receptors on pancreatic AR42J cells.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Bombesin; Bradykinin; Calcitonin Gene-Related Peptide; Calcium; Carbachol; Cholecystokinin; Epidermal Growth Factor; Estrenes; Fibroblast Growth Factors; GTP-Binding Proteins; Hydrolysis; Inositol Phosphates; Neuropeptides; Neurotransmitter Agents; Pancreas; Pancreatic Neoplasms; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein-Tyrosine Kinases; Pyrrolidinones; Rats; Receptors, Neuropeptide; Substance P; Tumor Cells, Cultured; Type C Phospholipases | 1995 |
Aminopeptidase P: cation activation and inhibitor sensitivity are substrate-dependent.
Topics: Amino Acid Sequence; Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cilazapril; Enalaprilat; Kidney; Kinetics; Molecular Sequence Data; Oligopeptides; Ramipril; Substance P; Substrate Specificity; Swine | 1995 |
Effects of three alpha 2-adrenoceptor agonists, rilmenidine, UK 14304 and clonidine on bradykinin- and substance P-induced airway microvascular leakage in guinea-pigs.
Topics: Acetylcholine; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Bradykinin; Brimonidine Tartrate; Capillaries; Capillary Permeability; Clonidine; Dioxanes; Extravascular Lung Water; Guinea Pigs; Idazoxan; Oxazoles; Prazosin; Quinoxalines; Rilmenidine; Substance P; Trachea | 1995 |
Colitis reduces short-circuit current response to inflammatory mediators in rat colonic mucosa.
Topics: Alprostadil; Animals; Anions; Bradykinin; Carbachol; Colitis; Intestinal Mucosa; Male; Mitomycin; Neutrophils; Patch-Clamp Techniques; Peroxidase; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Secretory Rate; Serotonin; Substance P; Theophylline; Time Factors | 1995 |
Blockade of mast cell histamine secretion in response to neurotensin by SR 48692, a nonpeptide antagonist of the neurotensin brain receptor.
Topics: Animals; Bradykinin; Dose-Response Relationship, Drug; Histamine; Histamine Release; Male; Mast Cells; Neurotensin; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Substance P; Time Factors | 1995 |
Role of the chymotrypsin-like membrane-associated proteinase from Treponema denticola ATCC 35405 in inactivation of bioactive peptides.
Topics: Amino Acid Sequence; Amino Acids; Angiotensin I; Bacterial Proteins; Bradykinin; Chymases; Cycloheximide; Humans; Molecular Sequence Data; Molecular Weight; Serine Endopeptidases; Substance P; Substrate Specificity; Treponema | 1995 |
Vasoconstrictor mechanism of neuropeptides augmented after endothelial removal in isolated, perfused canine basilar arteries.
Topics: Animals; Basilar Artery; Bradykinin; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Indomethacin; Male; Substance P; Vasoconstriction; Vasopressins | 1995 |
Involvement of tachykinins in plasma extravasation induced by bradykinin and low pH medium in the guinea-pig conjunctiva.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Capsaicin; Conjunctiva; Guinea Pigs; Hydrogen-Ion Concentration; Male; Neuritis; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Bradykinin; Substance P; Tachykinins | 1995 |
Altered reactivity of human cerebral arteries after subarachnoid hemorrhage.
Topics: Adult; Aged; Analysis of Variance; Bradykinin; Cerebral Arteries; Dinoprost; Epoprostenol; Female; Humans; In Vitro Techniques; Isometric Contraction; Male; Middle Aged; Muscle, Smooth, Vascular; Nitroglycerin; Norepinephrine; Serotonin; Subarachnoid Hemorrhage; Substance P | 1995 |
Inhibition by actinomycin D of neurogenic mouse ear oedema.
Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Capsaicin; Cycloheximide; Dactinomycin; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Ear Diseases; Edema; Histamine; Injections, Intravenous; Leukotriene C4; Male; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Substance P; Tachykinins; Vasoactive Intestinal Peptide | 1995 |
Mechanism of bradykinin-induced plasma extravasation in the rat knee joint.
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Blood Pressure; Bradykinin; Capillary Permeability; Enzyme Inhibitors; Indoles; Injections, Intra-Articular; Isoindoles; Knee Joint; Male; Mast Cells; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidopamine; Perfusion; Rats; Rats, Wistar; Regional Blood Flow; Serum Albumin; Substance P; Sympathectomy; Synovial Fluid | 1995 |
Investigations on the role of inflammatory and anti-inflammatory agents on the treatment of murine B cell leukemia by recombinant human interleukin-2.
Topics: Animals; Anti-Inflammatory Agents; Bradykinin; Dinoprostone; Freund's Adjuvant; Histamine; Inflammation; Interleukin-2; Leukemia, B-Cell; Lipopolysaccharides; Mice; Mice, Inbred BALB C; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Recombinant Proteins; Substance P | 1993 |
Investigation of postmortem functional changes in human cerebral arteries.
Topics: Adult; Aged; Autopsy; Bradykinin; Cerebral Arteries; Epoprostenol; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Nitroglycerin; Substance P; Time Factors | 1993 |
Effect of CP-96,345, a non-peptide NK1 receptor antagonist, against substance P-, bradykinin- and allergen-induced airway microvascular leakage and bronchoconstriction in the guinea pig.
Topics: Administration, Inhalation; Allergens; Animals; Biphenyl Compounds; Bradykinin; Bronchoconstriction; Extravasation of Diagnostic and Therapeutic Materials; Female; Guinea Pigs; Immunization; Injections, Intravenous; Microcirculation; Pulmonary Circulation; Substance P | 1993 |
Inhibitory action of (+/-)CP-96,345 on the cardiovascular responses to intrathecal substance P and neuropeptide K in the conscious freely moving rat.
Topics: Animals; Biphenyl Compounds; Bradykinin; Cardiovascular System; Hemodynamics; Injections, Intravenous; Injections, Spinal; Male; Neuropeptides; Rats; Rats, Wistar; Substance P; Tachykinins | 1993 |
Modulation of airway epithelial cell ciliary beat frequency by nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bradykinin; Bronchi; Cattle; Cilia; Epithelium; In Vitro Techniques; Isomerism; Isoproterenol; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Substance P | 1993 |
Effect of frusemide on bradykinin- and capsaicin-induced contraction of the guinea-pig trachea.
Topics: Animals; Bradykinin; Bronchoconstriction; Capsaicin; Furosemide; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Substance P; Trachea | 1993 |
Role of substance P in neurogenic inflammation in the rat incisor pulp and the lower lip.
Topics: Animals; Aspirin; Atropine; Bradykinin; Capillary Permeability; Cheilitis; Dental Pulp; Electric Stimulation; Histamine; Histamine Release; Incisor; Lip; Male; Mandibular Nerve; Methysergide; p-Methoxy-N-methylphenethylamine; Phentolamine; Propranolol; Pulpitis; Pyrilamine; Rats; Rats, Wistar; Substance P | 1993 |
Effects of capsaicin, (+/-)-CP-96,345 and SR 48968 on the bradykinin-induced airways microvascular leakage in guinea-pigs.
Topics: Animals; Autonomic Nervous System; Benzamides; Biphenyl Compounds; Bradykinin; Capillary Permeability; Capsaicin; Evans Blue; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Nerve Endings; Neurokinin A; Piperidines; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1993 |
Inhibitory effects of the neurotensin8-13 analogs Asp13-NT8-13 and Asp12-NT8-13 on mast cell secretion.
Topics: Amino Acid Sequence; Animals; Antibodies, Anti-Idiotypic; Biomarkers, Tumor; Bradykinin; Calcimycin; Calcium; Dose-Response Relationship, Drug; Histamine Release; Immunoglobulin E; Lymphokines; Male; Mast Cells; Molecular Sequence Data; Neurotensin; p-Methoxy-N-methylphenethylamine; Peptide Fragments; Rats; Rats, Sprague-Dawley; Substance P; Tumor Protein, Translationally-Controlled 1 | 1993 |
Differences in the properties and enzymatic specificities of the two active sites of angiotensin I-converting enzyme (kininase II). Studies with bradykinin and other natural peptides.
Topics: Amino Acid Sequence; Animals; Binding Sites; Bradykinin; Chlorides; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; DNA; Endothelium, Vascular; Gonadotropin-Releasing Hormone; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins; Sequence Deletion; Substance P; Substrate Specificity; Transfection | 1993 |
Interleukin-8 stimulates angiogenesis in rats.
Topics: Animals; Bradykinin; Drug Synergism; Interleukin-1; Interleukin-8; Male; Neovascularization, Pathologic; Rats; Rats, Wistar; Substance P; Surgical Sponges; Tumor Necrosis Factor-alpha | 1993 |
Substrate specificity of aminopeptidase Ey from hen's (Gallus domesticus) egg yolk.
Topics: Amino Acid Sequence; Aminopeptidases; Animals; Bradykinin; Brain Chemistry; Chickens; Egg Yolk; Female; Molecular Sequence Data; Nerve Tissue Proteins; Peptide Fragments; Proline; Substance P; Substrate Specificity | 1993 |
Effect of bradykinin and tachykinin receptor antagonist on xylene-induced cystitis in rats.
Topics: Administration, Intravesical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Cystitis; Female; Rats; Rats, Wistar; Substance P; Xylenes | 1993 |
Chimeric galanin analogs that function as antagonists in the CNS are full agonists in gastrointestinal smooth muscle.
Topics: Animals; Bradykinin; Cyclic AMP; Digestive System; Digestive System Physiological Phenomena; Galanin; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Peptides; Rats; Substance P | 1993 |
Substance P receptors on O-2A progenitor cells and type-2 astrocytes in vitro.
Topics: Animals; Astrocytes; Biological Transport; Bradykinin; Calcium; Cells, Cultured; Oligodendroglia; Phosphatidylinositols; Rats; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Stem Cells; Substance P | 1993 |
Role of kinins in the vascular extravasation evoked by antigen and mediated by tachykinins in guinea pig trachea.
Topics: Animals; Antigens; Biphenyl Compounds; Bradykinin; Capillary Permeability; Guinea Pigs; Kinins; Male; Neurons, Afferent; Ovalbumin; Substance P; Tachykinins; Trachea | 1993 |
Involvement of substance P present in small-diameter afferent fibers in microcirculatory hemodynamics of the rat hind instep.
Topics: Afferent Pathways; Animals; Bradykinin; Dose-Response Relationship, Drug; Hindlimb; Male; Microcirculation; Muscle, Smooth, Vascular; Neurokinin A; Peptide Fragments; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sciatic Nerve; Skin; Substance P | 1993 |
Does substance P release mediate NANC nerve-mediated responses to field stimulation and ligands, in the rabbit isolated sphincter pupillae?
Topics: Animals; Bradykinin; Capsaicin; Electric Stimulation; Isometric Contraction; Male; Muscle, Smooth; Neurokinin A; Neurons, Afferent; Physalaemin; Pupil; Rabbits; Receptors, Tachykinin; Structure-Activity Relationship; Substance P; Tachykinins | 1993 |
Desensitizing mechanism of capsaicin and nonanoyl vanillylamide on the vascular nociceptive response in the guinea pig.
Topics: Acetylcholine; Animals; Bradykinin; Capsaicin; Ganglia, Spinal; Guinea Pigs; Injections, Intra-Arterial; Injections, Spinal; Injections, Subcutaneous; Male; Pain; Spinal Cord; Substance P; Vanillic Acid; Vocalization, Animal | 1993 |
Antiinflammatory and analgesic activity of CP-96,345: an orally active non-peptide substance P receptor antagonist.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Dose-Response Relationship, Drug; Evans Blue; Guinea Pigs; Histamine; Leukotriene D4; Male; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Platelet Activating Factor; Receptors, Neurokinin-1; Skin; Substance P; Ureter | 1993 |
Role of prostaglandins in renal sensory receptor activation by substance P and bradykinin.
Topics: Animals; Bradykinin; Capsaicin; Denervation; Dose-Response Relationship, Drug; Indomethacin; Kidney; Male; Nervous System; Prostaglandins; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Substance P | 1993 |
Neurogenic inflammation in the chicken (Gallus gallus var domesticus).
Topics: Anesthesia; Animals; Bradykinin; Chickens; Comb and Wattles; Electric Stimulation; Evans Blue; Female; Hot Temperature; Isothiocyanates; Nerve Fibers; Neuritis; Nociceptors; Physical Stimulation; Skin Physiological Phenomena; Substance P; Trigeminal Nerve | 1993 |
Effects of cromakalim on bradykinin-, histamine- and substance P-induced airway microvascular leakage in the guinea-pig.
Topics: Animals; Benzopyrans; Bradykinin; Bronchi; Capillary Permeability; Cromakalim; Electric Stimulation; Evans Blue; Female; Guinea Pigs; Histamine; In Vitro Techniques; Injections, Intravenous; Lung; Male; Muscle Contraction; Muscle, Smooth; Pyrroles; Respiratory System; Substance P; Trachea | 1993 |
Differential effects of the putative galanin receptor antagonists M15 and M35 on striatal acetylcholine release.
Topics: Acetylcholine; Animals; Bradykinin; Brain; Chromatography, High Pressure Liquid; Galanin; Male; Microdialysis; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Galanin; Receptors, Gastrointestinal Hormone; Substance P | 1993 |
Nedocromil sodium reduces allergen-induced plasma extravasation in the guinea pig nasal mucosa by inhibition of tachykinin release.
Topics: Allergens; Animals; Anti-Allergic Agents; Bradykinin; Capillary Permeability; Cromolyn Sodium; Guinea Pigs; Male; Nasal Mucosa; Nedocromil; Ovalbumin; Substance P; Tachykinins | 1995 |
Activation of protein kinase C augments peptide release from rat sensory neurons.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Carcinogens; Cells, Cultured; Down-Regulation; Enzyme Activation; Female; Mice; Neurons, Afferent; Neuropeptides; Phorbol 12,13-Dibutyrate; Potassium; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Substance P | 1996 |
Potentiation by bradykinin and substance P of purinergic neurotransmission in urinary bladder.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Receptors, Purinergic; Substance P; Urinary Bladder | 1996 |
The effects of EDRF/NO releasers or calcium ionophore A23187 on cyanide toxicity in mice.
Topics: Animals; Bradykinin; Calcimycin; Carbachol; Cyanides; Hydralazine; Ionophores; Lethal Dose 50; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Seizures; Substance P; Survival Rate | 1996 |
Substance P enhances antigen-evoked mediator release from human nasal mucosa.
Topics: Adult; Allergens; Bradykinin; Dose-Response Relationship, Drug; Female; Histamine Release; Humans; Immunoglobulin E; Male; Mast Cells; Nasal Mucosa; Peptide Hydrolases; Rhinitis, Allergic, Seasonal; Substance P | 1996 |
The effect of bradykinin and substance P on the arachidonate cascade of platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Blood Platelets; Bradykinin; Dose-Response Relationship, Drug; Eicosanoids; In Vitro Techniques; Male; Platelet Activation; Rats; Rats, Wistar; Receptor, Bradykinin B1; Receptors, Bradykinin; Receptors, Neurokinin-1; Substance P; Thromboxane A2 | 1996 |
Hybrid peptides having mixed substance P (NK1), neurokinin A (NK2) and bradykinin (BK2) antagonist properties.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Molecular Structure; Neurokinin A; Neurokinin-1 Receptor Antagonists; Oligopeptides; Pulmonary Artery; Rabbits; Receptor, Bradykinin B2; Receptors, Neurokinin-2; Structure-Activity Relationship; Substance P | 1996 |
Modulation by opioid peptides of mechanosensory pathways supplying the guinea-pig inferior mesenteric ganglion.
Topics: Animals; Bradykinin; Ganglia; Guinea Pigs; Male; Neural Pathways; Opioid Peptides; Radioimmunoassay; Substance P; Tetrodotoxin; Vasoactive Intestinal Peptide | 1996 |
Polysensory response characteristics of dorsal root ganglion neurones that may serve sensory functions during myocardial ischaemia.
Topics: Adenosine; Adenosine Triphosphate; Animals; Bradykinin; Dogs; Female; Ganglia, Spinal; Male; Myocardial Ischemia; Neurons; Stimulation, Chemical; Stress, Mechanical; Substance P; Synaptic Transmission | 1996 |
Prostaglandin E2 increases the proportion of neonatal rat dorsal root ganglion neurons that respond to bradykinin.
Topics: Animals; Animals, Newborn; Bradykinin; Bradykinin Receptor Antagonists; Calcium; Cell Size; Cells, Cultured; Dinoprostone; Epoprostenol; Ganglia, Spinal; Immunohistochemistry; Neurons; Rats; Rats, Sprague-Dawley; Substance P | 1996 |
Role of tachykinins in enhancement of bradykinin-induced bronchoconstriction by captopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzamides; Bradykinin; Bronchoconstriction; Capsaicin; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Male; Neurokinin A; Peptides, Cyclic; Piperidines; Substance P | 1996 |
Effect of the non-peptide blocker (+/-) CP 96,345 on the cellular mechanism involved in the response to NK1 receptor stimulation in human skin fibroblasts.
Topics: Biphenyl Compounds; Bradykinin; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Dipeptides; Fibroblasts; Humans; Hydrolysis; Indoles; Neurokinin-1 Receptor Antagonists; Phosphatidylinositols; Physalaemin; Receptors, Neurokinin-1; Skin; Stimulation, Chemical; Substance P | 1996 |
Changes in nitric oxide release in vivo in response to vasoactive substances.
Topics: Animals; Bradykinin; Epoprostenol; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Rats; Rats, Wistar; Substance P | 1996 |
Influence of several peptidase inhibitors on the pro-inflammatory effects of substance P, capsaicin and collagenase.
Topics: Albumins; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Capillary Permeability; Capsaicin; Captopril; Collagenases; Dose-Response Relationship, Drug; Edema; Glycopeptides; Hindlimb; Indoles; Inflammation; Isoindoles; Male; Matrix Metalloproteinase Inhibitors; Methysergide; Neurokinin-1 Receptor Antagonists; Oligopeptides; Organ Size; Protease Inhibitors; Rats; Rats, Wistar; Serotonin Antagonists; Substance P | 1996 |
Pharmacological activation changes stiffness of cultured human airway smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Actins; Bradykinin; Bronchodilator Agents; Bucladesine; Carbachol; Cells, Cultured; Colforsin; Collagen; Cytoskeleton; Dinoprostone; Histamine; Humans; Isoproterenol; Kinetics; Magnetics; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Myosins; Potassium Chloride; Substance P; Time Factors; Trachea | 1996 |
Inhibition of hind-paw edema and cutaneous vascular plasma extravasation by 2-chloro-3-methoxycarbonylpropionamido-1,4-naphthoquinone (PP1D1) in mice.
Topics: Animals; Anti-Inflammatory Agents; Bradykinin; Capillary Permeability; Edema; Mice; Mice, Inbred ICR; Naphthoquinones; Passive Cutaneous Anaphylaxis; Serotonin; Substance P | 1996 |
Antiinflammatory and analgesic activity of an inhibitor of neuropeptide amidation.
Topics: Amidine-Lyases; Amino Acid Sequence; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Carrageenan; Edema; Fatty Acids, Monounsaturated; Inflammation; Kinetics; Lyases; Male; Mice; Mixed Function Oxygenases; Multienzyme Complexes; Rats; Rats, Sprague-Dawley; Serotonin; Substance P; Substrate Specificity | 1997 |
Central modulation of Brewer's yeast-induced peripheral inflammation by neuropeptides bradykinin and substance P.
Topics: Analgesics; Animals; Bradykinin; Edema; Inflammation; Male; Pain; Rats; Rats, Sprague-Dawley; Saccharomyces cerevisiae; Substance P | 1996 |
Sodium metabisulfite and citric acid induce bronchoconstriction via a sulfite-sensitive pathway in the isolated guinea pig lung.
Topics: Acetylcholine; Administration, Inhalation; Airway Resistance; Animals; Autacoids; Bradykinin; Bronchi; Bronchoconstriction; Bronchoconstrictor Agents; Calcitonin Gene-Related Peptide; Citric Acid; Guinea Pigs; Histamine; Hydrogen-Ion Concentration; In Vitro Techniques; Lung; Lung Compliance; Male; Neurokinin A; Neurons, Afferent; Serotonin; Substance P; Sulfites | 1997 |
Spontaneously released substance P and bradykinin from isolated guinea-pig bladder.
Topics: Animals; Bradykinin; Captopril; Female; Glycopeptides; Guinea Pigs; Muscle Contraction; Peptidyl-Dipeptidase A; Protease Inhibitors; Substance P; Urinary Bladder | 1997 |
Enrichment of the fraction of nociceptive neurones in cultures of primary sensory neurones.
Topics: Animals; Animals, Newborn; Antibody Specificity; Bradykinin; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cell Separation; Cell Size; Cells, Cultured; Ganglia, Spinal; Immunohistochemistry; Microscopy, Confocal; Neurons, Afferent; Nociceptors; Rats; Rats, Wistar; Substance P | 1997 |
Substance P and bradykinin stimulate plasma extravasation in the mouse gastrointestinal tract and pancreas.
Topics: Animals; Bradykinin; Capillary Permeability; Capsaicin; Coloring Agents; Digestive System; Evans Blue; Indoles; Mice; Mice, Inbred Strains; Organometallic Compounds; Pancreas; Plasma; Substance P; Venules | 1997 |
Involvement of 5-hydroxytryptamine and bradykinin in the hyperalgesia induced in rats by collagenase from Clostridium histolyticum.
Topics: Analgesics; Angiotensin-Converting Enzyme Inhibitors; Animals; Behavior, Animal; Bradykinin; Clostridium; Edema; Female; Hindlimb; Hyperalgesia; Indoles; Isoindoles; Kininogens; Lisinopril; Methysergide; Microbial Collagenase; Neurokinin-1 Receptor Antagonists; Ondansetron; Prostaglandins; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Substance P | 1997 |
Analysis of bioactive peptides by liquid chromatography-high-resolution electrospray mass spectrometry.
Topics: Bradykinin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Enkephalins; Mass Spectrometry; Molecular Weight; Peptide Fragments; Peptides; Substance P; Trypsin | 1997 |
Vaso-reactivity of isolated bovine intra-mammary artery to endogenous prostanoids and nitric oxide.
Topics: Animals; Bradykinin; Cattle; Cyclooxygenase Inhibitors; Drug Interactions; Endothelin-1; Female; Indomethacin; Mammary Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Substance P; Vasoconstriction | 1997 |
Effect of octreotide, a somatostatin analogue, on release of inflammatory mediators from isolated guinea pig bladder.
Topics: Animals; Bradykinin; Female; Guinea Pigs; Histamine Release; In Vitro Techniques; Inflammation Mediators; Leukotrienes; Neurokinin A; Octreotide; Prostaglandins; Substance P; Urinary Bladder | 1997 |
Inhibition by nociceptin of neurogenic inflammation and the release of SP and CGRP from sensory nerve terminals.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Electric Stimulation; Inflammation; Nociceptin; Opioid Peptides; Rats; Sensory Receptor Cells; Substance P; Trachea | 1997 |
Neuroligand-triggered calcium signalling in cultured human glioma cells.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Angiotensin II; Bradykinin; Calcium; Fluorescent Dyes; Glioblastoma; Glucose; Histamine; Humans; Neurotransmitter Agents; Norepinephrine; Oligodendroglioma; Potassium; Serotonin; Signal Transduction; Substance P; Tumor Cells, Cultured; Vasoconstrictor Agents | 1997 |
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry as a tool to probe the reactions of trans-Hex-2-enal with proteins.
Topics: Aldehydes; Bradykinin; Cytochrome c Group; Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substance P | 1997 |
Bradykinin-mediated activation of renal sensory neurons due to prostaglandin-dependent release of substance P.
Topics: Animals; Biphenyl Compounds; Bradykinin; Indoles; Indomethacin; Isoindoles; Kidney; Male; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Piperidines; Prostaglandins; Prostaglandins E; Rats; Rats, Sprague-Dawley; Substance P | 1997 |
Vasodilator responses to acetylcholine, bradykinin, and substance P are mediated by a TEA-sensitive mechanism.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Albuterol; Alprostadil; Analysis of Variance; Angiotensin II; Animals; Benzopyrans; Blood Pressure; Bradykinin; Cats; Cromakalim; Endothelium, Vascular; Female; Glyburide; Heart Rate; Hindlimb; Hydrazines; Isradipine; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitrogen Oxides; Nitroprusside; Norepinephrine; Penicillamine; Prostaglandin Endoperoxides, Synthetic; Pyrroles; S-Nitroso-N-Acetylpenicillamine; Substance P; Tetraethylammonium; Tetraethylammonium Compounds; Thromboxane A2; Vasoactive Intestinal Peptide; Vasodilation; Vasodilator Agents | 1997 |
The control of microvascular permeability and blood pressure by neutral endopeptidase.
Topics: Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Capillaries; Capillary Permeability; Female; Male; Mice; Mice, Inbred C57BL; Neprilysin; Neurokinin-1 Receptor Antagonists; Substance P; Venules | 1997 |
L-arginine prevents cyclosporin A-induced pulmonary vascular dysfunction.
Topics: Acetylcholine; Animals; Arginine; Atrial Function, Left; Blood Pressure; Bradykinin; Cyclooxygenase Inhibitors; Cyclosporine; Dogs; Endothelium, Vascular; Indomethacin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Peptidyl-Dipeptidase A; Pulmonary Artery; Pulmonary Circulation; Substance P; Vasodilation; Vasodilator Agents | 1997 |
Kinin receptors in the diabetic mouse.
Topics: Acetylcholine; Animals; Bradykinin; Diabetes Mellitus, Experimental; Gastric Fundus; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Neurokinin A; Receptors, Tachykinin; Reference Values; Substance P | 1997 |
Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2.
Topics: Adrenergic beta-Antagonists; Animals; Benzimidazoles; Bradykinin; Calcium; Cells, Cultured; Chymases; Colon; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Gastrointestinal Motility; In Vitro Techniques; Indomethacin; Inflammation Mediators; Leupeptins; Mast Cells; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitroprusside; Rats; Receptor, PAR-2; Receptors, Cell Surface; Serine Endopeptidases; Substance P; Tetrodotoxin; Time Factors; Trypsin; Tryptases | 1997 |
Histamine release from human bronchoalveolar lavage mast cells by neurokinin A and bradykinin.
Topics: Bradykinin; Bronchoalveolar Lavage Fluid; Calcimycin; Female; Histamine Release; Humans; Ionophores; Male; Mast Cells; Middle Aged; Neurokinin A; p-Methoxy-N-methylphenethylamine; Substance P | 1997 |
Differential effects of L-N5-(1-iminoethyl)-ornithine on tone and endothelium-dependent vasodilator responses.
Topics: Acetylcholine; Adenosine; Adrenomedullin; Animals; Arginine; Blood Pressure; Bradykinin; Cats; Endothelium, Vascular; Female; Guanidines; Male; Muscle Tonus; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Ornithine; Peptides; Pinacidil; Pulmonary Artery; Pulmonary Circulation; Substance P; Vasodilation; Vasodilator Agents | 1997 |
Neurokinin A-LI release after antigen challenge in guinea-pig bronchial tubes: influence of histamine and bradykinin.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Bronchi; Capsaicin; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Ovalbumin; Pyrilamine; Substance P; Trachea | 1997 |
Antinociceptive properties of the hydroalcoholic extract and preliminary study of a xanthone isolated from Polygala cyparissias (Polygalaceae).
Topics: Abdominal Pain; Acetic Acid; Analgesia; Analgesics; Animals; Aspirin; Bradykinin; Capsaicin; Ethanol; Hot Temperature; Male; Pain; Pain Measurement; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Substance P; Water; Xanthenes; Xanthones | 1997 |
Vasorelaxation in isolated bone arteries. Vasoactive intestinal peptide, substance P, calcitonin gene-related peptide, and bradykinin studied in pigs.
Topics: Animals; Bone and Bones; Bradykinin; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Female; Male; Substance P; Swine; Vasoactive Intestinal Peptide; Vasodilation | 1997 |
Kinetics of peptide-induced release of inflammatory mediators by the urinary bladder.
Topics: Animals; Bradykinin; Cystitis; Dinoprost; Dinoprostone; Female; Guinea Pigs; Histamine; Inflammation Mediators; Leukotriene B4; Peptides; Somatostatin; Substance P | 1997 |
Substance P is generated in vivo following nasal challenge of allergic individuals with bradykinin.
Topics: Adolescent; Adult; Bradykinin; Female; Humans; Hypersensitivity, Immediate; Male; Middle Aged; Nasal Lavage Fluid; Nasal Mucosa; Nasal Provocation Tests; Peptide Hydrolases; Substance P | 1997 |
Pharmacologic characteristics of rabbit esophageal muscularis mucosae in vitro.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adrenergic Agonists; Adrenergic beta-Agonists; Animals; Bradykinin; Electric Stimulation; Esophagus; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Norepinephrine; Phentolamine; Propranolol; Prostaglandins; Rabbits; Receptors, Purinergic; Substance P | 1997 |
Distinct endothelial impairment in coronary microvessels from hypertensive Dahl rats.
Topics: Acetylcholine; Animals; Bradykinin; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Endothelium, Vascular; Fatty Acids, Unsaturated; Hypertension; In Vitro Techniques; Indomethacin; Male; Microcirculation; Nitroarginine; Rats; Rats, Inbred Strains; Sodium, Dietary; Substance P; Vasodilation | 1998 |
Inhibitory effect of somatostatin on the mechanosensitivity of articular afferents in normal and inflamed knee joints of the rat.
Topics: Afferent Pathways; Animals; Arthritis; Bradykinin; Knee Joint; Male; Rats; Rats, Wistar; Reference Values; Somatostatin; Stress, Mechanical; Substance P | 1997 |
ATP release caused by bradykinin, substance P and histamine from intact and cultured smooth muscles of guinea-pig vas deferens.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Guinea Pigs; Histamine; Male; Muscle, Smooth; Substance P; Vas Deferens | 1998 |
Sensitive high-resolution analysis of biological molecules by capillary zone electrophoresis coupled with reflecting time-of-flight mass spectrometry.
Topics: Acetic Acid; Angiotensinogen; Animals; Bradykinin; Cattle; Cytochrome c Group; Electrophoresis, Capillary; Gonadotropin-Releasing Hormone; Insulin; Mass Spectrometry; Myoglobin; Peptides; Proteins; Reference Standards; Substance P | 1998 |
Identification of bradykinin, substance P, and neurokinin A in human dental pulp.
Topics: Animals; Bradykinin; Cattle; Chromatography, High Pressure Liquid; Dental Pulp; Humans; Inflammation Mediators; Neurokinin A; Neurotransmitter Agents; Serum Albumin, Bovine; Substance P | 1997 |
A study of prolyl endopeptidase in bovine serum and its relevance to the tissue enzyme.
Topics: Angiotensin II; Animals; Binding, Competitive; Bradykinin; Cattle; Chloromercuribenzoates; Coumarins; Enzyme Inhibitors; Enzyme Stability; Fluorometry; Gonadotropin-Releasing Hormone; Hydrogen-Ion Concentration; Metals; Molecular Weight; Neuropeptides; p-Chloromercuribenzoic Acid; Prolyl Oligopeptidases; Serine Endopeptidases; Substance P; Substrate Specificity | 1998 |
Acute ACE inhibition causes plasma extravasation in mice that is mediated by bradykinin and substance P.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Coloring Agents; Data Interpretation, Statistical; Enalapril; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Indicators and Reagents; Indoles; Injections, Intravenous; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Organometallic Compounds; Piperidines; Quinuclidines; Substance P; Time Factors | 1998 |
High-performance liquid chromatographic analysis with diode-array detection of bradykinin, neuropeptide K, and substance P in human plasma.
Topics: Bradykinin; Calibration; Chromatography, High Pressure Liquid; Humans; Neuropeptides; Plasma; Reproducibility of Results; Spectrophotometry, Ultraviolet; Substance P; Tachykinins | 1998 |
Inhibition of nociceptin on sensory neuropeptide release and mast cell-mediated plasma extravasation in rats.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Coloring Agents; Denervation; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Female; Hindlimb; Mast Cells; Nociceptin; Opioid Peptides; Peptides; Rats; Rats, Wistar; Somatostatin; Substance P | 1998 |
Angiotensin 1-7 induces bradykinin-mediated relaxation in porcine coronary artery.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Coronary Vessels; Imidazoles; In Vitro Techniques; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Receptor, Bradykinin B2; Receptors, Bradykinin; Substance P; Swine; Vasodilation | 1998 |
Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae).
Topics: Abdominal Pain; Acetic Acid; Animals; Bradykinin; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Hyperalgesia; Male; Mice; Motor Activity; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Sesquiterpenes; Substance P; Zymosan | 1998 |
Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery after experimental subarachnoid hemorrhage.
Topics: Adenoviridae; Animals; Basilar Artery; beta-Galactosidase; Bradykinin; Dogs; Enzyme Inhibitors; Female; Genes, Reporter; Genetic Therapy; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Subarachnoid Hemorrhage; Substance P; Vasoconstriction; Vasodilation | 1998 |
Endothelial dysfunction in human intramyocardial small arteries in atherosclerosis and hypercholesterolemia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adult; Arteries; Arteriosclerosis; Bradykinin; Cardiomyopathies; Coronary Circulation; Endothelium, Vascular; Female; Heart; Heart Failure; Heart Transplantation; Humans; Hypercholesterolemia; In Vitro Techniques; Isometric Contraction; Male; Middle Aged; Nitroprusside; Substance P; Vasodilation | 1998 |
Pharmacologic activation of the human coronary microcirculation in vitro: endothelium-dependent dilation and differential responses to acetylcholine.
Topics: Acetylcholine; Adenosine Diphosphate; Adolescent; Adult; Aged; Aged, 80 and over; Arachidonic Acid; Bradykinin; Calcimycin; Child; Child, Preschool; Coronary Circulation; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Heart Atria; Heart Ventricles; Humans; In Vitro Techniques; Infant; Infant, Newborn; Ionophores; Male; Microcirculation; Middle Aged; Stimulation, Chemical; Substance P; Vasoconstriction; Vasodilator Agents | 1998 |
Vascular protein leakage in the rat parotid gland elicited by reflex stimulation, parasympathetic nerve stimulation and administration of neuropeptides.
Topics: Animals; Blood Proteins; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Electric Stimulation; Evans Blue; Female; Food; Male; Neurokinin A; Neuropeptides; Parasympathetic Nervous System; Parotid Gland; Pilocarpine; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Substance P; Vasoactive Intestinal Peptide | 1998 |
Activity of tachykinin NK1 and bradykinin B2 receptor antagonists, and an opioid ligand at different stimulation parameters in neurogenic inflammation in the rat.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Edema; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Extravasation of Diagnostic and Therapeutic Materials; Male; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Peptide Fragments; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptor, Bradykinin B2; Receptors, Neurokinin-1; Receptors, Opioid, mu; Substance P; Time Factors | 1998 |
Oral anti-inflammatory action of NPC 18884, a novel bradykinin B2 receptor antagonist.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Carrageenan; Dipeptides; Disease Models, Animal; Drug Interactions; Female; Histamine; Male; Mice; Pleurisy; Receptor, Bradykinin B2; Substance P | 1998 |
Role of neuropeptides in pathogenesis of reflex sympathetic dystrophy.
Topics: Adult; Aged; Bradykinin; Calcitonin Gene-Related Peptide; Female; Humans; Inflammation; Male; Middle Aged; Neuropeptides; Reflex Sympathetic Dystrophy; Substance P; Vasoactive Intestinal Peptide | 1998 |
Influence of interleukin-1 beta on bradykinin-induced responses in guinea pig peritoneal macrophages.
Topics: Animals; Bradykinin; Calcium; Female; Guinea Pigs; In Vitro Techniques; Interleukin-1; Macrophages, Peritoneal; N-Formylmethionine Leucyl-Phenylalanine; Respiratory Burst; Substance P; Superoxides | 1999 |
Neurogenic plasma leakage in mouse airways.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzamides; Blood Vessels; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Capsaicin; Captopril; Dose-Response Relationship, Drug; Evans Blue; Glycopeptides; Lung; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Piperidines; Protease Inhibitors; Quinuclidines; Receptors, Neurokinin-2; Skin; Specific Pathogen-Free Organisms; Substance P; Trachea; Urinary Bladder | 1999 |
Suggestive evidence for inhibitory effects of galanin on mesolimbic dopaminergic neurotransmission.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Bradykinin; Brain Chemistry; Dopamine; Dose-Response Relationship, Drug; Galanin; Hippocampus; Injections, Intraventricular; Levodopa; Locomotion; Male; Motor Activity; Neocortex; Neostriatum; Neural Inhibition; Nucleus Accumbens; Olfactory Bulb; Peptide Fragments; Rats; Rats, Wistar; Substance P; Synaptic Transmission; Ventral Tegmental Area | 1999 |
Release of substance P, calcitonin gene-related peptide and prostaglandin E2 from rat dura mater encephali following electrical and chemical stimulation in vitro.
Topics: Afferent Pathways; Animals; Arachnoid; Bradykinin; Calcitonin Gene-Related Peptide; Dinoprostone; Dura Mater; Electric Stimulation; Headache; Histamine; Inflammation; Male; Migraine Disorders; Neurons, Afferent; Nociceptors; Organ Culture Techniques; Rats; Rats, Wistar; Serotonin; Substance P; Trigeminal Ganglion; Vasodilation | 1999 |
Lack of evidence for tachykinin NK1 receptor-mediated neutrophil accumulation in the rat cutaneous microvasculature by thermal injury.
Topics: Abdomen; Animals; Bradykinin; Burns; Dose-Response Relationship, Drug; Edema; Hindlimb; Histamine; Inflammation; Interleukin-1; Male; Microcirculation; Mustard Plant; Neurokinin-1 Receptor Antagonists; Neutrophils; Peptide Fragments; Piperidines; Plant Extracts; Plant Oils; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Skin; Substance P; Time Factors | 1999 |
On the regulation of tone in vasa vasorum.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Aorta; Bradykinin; Calcitonin Gene-Related Peptide; Cattle; Dose-Response Relationship, Drug; Endothelin-1; In Vitro Techniques; Isoproterenol; Norepinephrine; Prostaglandin Endoperoxides, Synthetic; Substance P; Swine; Vasa Vasorum; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Bradykinin activates a cross-signaling pathway between sensory and adrenergic nerve endings in the heart: a novel mechanism of ischemic norepinephrine release?
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Nerve Endings; Neurons, Afferent; Norepinephrine; Signal Transduction; Substance P; Synaptosomes | 1999 |
Evaluation of the efficacy of a bioerodible bupivacaine polymer system on antinociception and inflammatory mediator release.
Topics: Anesthetics, Local; Animals; Biocompatible Materials; Biodegradation, Environmental; Bradykinin; Bupivacaine; Drug Implants; Immunohistochemistry; Inflammation Mediators; Lactic Acid; Male; Microdialysis; Pain; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley; Substance P | 1999 |
Tumour necrosis factor-alpha mediates carrageenin-induced knee-joint incapacitation and also triggers overt nociception in previously inflamed rat knee-joints.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Bradykinin; Bradykinin Receptor Antagonists; Carrageenan; Dinoprostone; Inflammation Mediators; Injections, Intra-Articular; Knee Joint; Male; Pain; Rats; Rats, Wistar; Stimulation, Chemical; Substance P; Tumor Necrosis Factor-alpha | 1999 |
Chemically, mechanically, and hyperosmolarity-induced calcium responses of rat cortical capillary endothelial cells in culture.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcimycin; Calcium; Capillaries; Carbachol; Cells, Cultured; Cerebral Cortex; Endothelium, Vascular; Fluorescent Dyes; Fura-2; Histamine; Hypertonic Solutions; Norepinephrine; Rats; Rats, Wistar; Substance P; Thimerosal | 1999 |
Direct neurite-mast cell communication in vitro occurs via the neuropeptide substance P.
Topics: Animals; Bradykinin; Calcium; Cell Communication; Coculture Techniques; Fluorescence; Ganglia, Sympathetic; Immune Sera; Immunohistochemistry; Leukemia, Basophilic, Acute; Mast Cells; Mice; Mice, Inbred CBA; Neurites; Rats; Receptors, IgE; Scorpion Venoms; Substance P; Tumor Cells, Cultured | 1999 |
Substance P and bradykinin activate different types of KCa currents to hyperpolarize cultured porcine coronary artery endothelial cells.
Topics: Algorithms; Animals; Apamin; Bradykinin; Cells, Cultured; Coronary Vessels; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Fluorescent Dyes; Fura-2; Intermediate-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Microelectrodes; Muscle Contraction; Oxygenases; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Substance P; Swine | 1999 |
A new experimental approach in endothelium-dependent pharmacological investigations on isolated porcine coronary arteries mounted for impedance planimetry.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Calcimycin; Captopril; Coronary Vessels; Diffusion; Dinoprost; Dose-Response Relationship, Drug; Electric Impedance; Endothelium, Vascular; In Vitro Techniques; Isometric Contraction; Nitroprusside; Peptidyl-Dipeptidase A; Potassium; Pressure; Substance P; Swine; Time Factors; Vasoconstriction; Vasodilation | 1999 |
The involvement of K+ channels and Gi/o protein in the antinociceptive action of the gallic acid ethyl ester.
Topics: Analgesics; Animals; Bradykinin; Dose-Response Relationship, Drug; Drug Interactions; Foot; Gallic Acid; GTP-Binding Proteins; Male; Mice; Muscle Relaxation; Muscle, Skeletal; Pain Measurement; Pertussis Toxin; Potassium Channels; Rats; Rats, Wistar; Substance P; Time Factors; Virulence Factors, Bordetella | 1999 |
Sensory nerve activation in airway microvascular permeability in guinea-pig late allergic response.
Topics: Animals; Bradykinin; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Capillary Permeability; Guinea Pigs; Male; Microcirculation; Nerve Fibers; Receptors, Neurokinin-1; Respiratory Hypersensitivity; Sensory Receptor Cells; Substance P; Tachykinins; Trachea | 1999 |
Role of nitric oxide in the control of cardiac oxygen consumption in B(2)-kinin receptor knockout mice.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Calcium Channel Blockers; Drug Interactions; Enzyme Inhibitors; Female; Heart; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen Consumption; Ramipril; Receptors, Bradykinin; Substance P | 1999 |
L-type Ca2+ channels are not involved in coronary endothelial Ca2+ influx mechanism responsible for endothelium-dependent relaxation.
Topics: Analysis of Variance; Animals; Bradykinin; Calcium; Calcium Channel Blockers; Calcium Channels; Coronary Vessels; Diltiazem; Endothelium, Vascular; Female; Male; Nicardipine; Nitric Oxide; Substance P; Swine; Verapamil | 1999 |
Effects of NO donors and synthase agonists on endothelial cell uptake of L-Arg and superoxide production.
Topics: Animals; Aorta; Arginine; Biological Transport; Bradykinin; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Hydrazines; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Penicillamine; Substance P; Superoxides; Tritium | 2000 |
Effects of recombinant eNOS gene expression on reactivity of small cerebral arteries.
Topics: Animals; Bradykinin; Brain Stem; Cerebral Arteries; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression; In Vitro Techniques; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Recombinant Proteins; Substance P; Vasoconstriction; Vasodilation; Vasomotor System | 2000 |
Metastable decay of peptide ions on a Fourier transform mass spectrometer equipped with an external ion source.
Topics: Bradykinin; Fourier Analysis; Lasers; Peptides; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substance P | 2000 |
Maturation of the response to bradykinin in resistance and conduit pulmonary arteries.
Topics: Acetylcholine; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Bradykinin; Captopril; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Oxygen; Pulmonary Artery; Substance P; Swine; Vasoconstriction | 1999 |
Enhanced nociception by exogenous and endogenous substance P given into the spinal cord in mice lacking NR(2)A/epsilon(1), an NMDA receptor subunit.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Bradykinin; Capsaicin; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections, Spinal; Male; Mice; Mice, Knockout; Nerve Fibers; Neurokinin-1 Receptor Antagonists; Pain; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Substance P | 2000 |
Activation of renal mechanosensitive neurons involves bradykinin, protein kinase C, PGE(2), and substance P.
Topics: Adrenergic beta-Antagonists; Analgesics; Animals; Antimetabolites; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Indoles; Isoindoles; Kidney; Kidney Pelvis; Male; Mechanoreceptors; Naphthalenes; Natriuresis; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Pressure; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Receptors, Bradykinin; Receptors, Neurokinin-1; Substance P | 2000 |
Impaired endothelium-dependent regulation of ventricular relaxation in pressure-overload cardiac hypertrophy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Endothelium, Vascular; Guinea Pigs; Hypertrophy, Left Ventricular; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Substance P; Vasodilator Agents | 2000 |
Lipopolysaccharide-induced lung injury in mice. II. Evaluation of functional damage in isolated parenchyma strips.
Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Bradykinin; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Histamine; Lipopolysaccharides; Lung Diseases; Methacholine Chloride; Mice; Muscle Contraction; Pentoxifylline; Serotonin; Substance P | 2000 |
Neurokinin-1 receptor agonists are involved in mediating neutrophil accumulation in the inflamed, but not normal, cutaneous microvasculature: an in vivo study using neurokinin-1 receptor knockout mice.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Carrageenan; Cell Movement; Drug Combinations; Female; Injections, Intradermal; Injections, Intravenous; Interleukin-1; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Neutrophils; Receptors, Neurokinin-1; Skin; Substance P; Zymosan | 2000 |
Distribution of neuropeptides, histamine content, and inflammatory cells in the ureter.
Topics: Animals; Bradykinin; Histamine; Leukocytes; Mast Cells; Neurokinin A; Substance P; Swine; Ureter | 2000 |
Association between kinin B(1) receptor expression and leukocyte trafficking across mouse mesenteric postcapillary venules.
Topics: Animals; Bradykinin; Capillaries; Cell Movement; Endothelium, Vascular; Gene Expression; Interleukin-1; Leukocytes; Male; Mesenteric Veins; Mesentery; Mice; Mice, Knockout; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Substance P; Venules | 2000 |
Cardiovascular actions of python bradykinin and substance P in the anesthetized python, Python regius.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alligators and Crocodiles; Animals; Boidae; Bradykinin; Cardiovascular System; Epinephrine; Female; Male; Norepinephrine; Prazosin; Sotalol; Substance P; Turtles | 2000 |
Mechanisms underlying the reduced endothelium-dependent relaxation in human omental resistance artery in pre-eclampsia.
Topics: Adult; Benzimidazoles; Bradykinin; Calcium; Calcium Channel Agonists; Cyclic GMP; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Omentum; Potassium; Pre-Eclampsia; Pregnancy; Substance P; Thromboxane A2; Vasodilation | 2000 |
Prostaglandin E2-induced sensitization of bradykinin-evoked responses in rat dorsal root ganglion neurons is mediated by cAMP-dependent protein kinase A.
Topics: Adenylyl Cyclases; Animals; Bradykinin; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Ganglia, Spinal; Inositol 1,4,5-Trisphosphate; Isoquinolines; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Substance P; Sulfonamides; Tritium | 2000 |
Sensitization of rat sensory neurons by chronic exposure to forskolin or 'inflammatory cocktail' does not downregulate and requires continuous exposure.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Cells, Cultured; Colforsin; Cyclic AMP; Embryo, Mammalian; Female; Ganglia, Spinal; Inflammation Mediators; Neurons, Afferent; Pregnancy; Rats; Rats, Sprague-Dawley; Substance P | 2000 |
Inhibitor potencies and substrate preference for endothelin-converting enzyme-1 are dramatically affected by pH.
Topics: Aspartic Acid Endopeptidases; Bradykinin; Endothelin-Converting Enzymes; Humans; Hydrogen-Ion Concentration; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Quinazolines; Substance P; Substrate Specificity; Tetrazoles | 2000 |
Antinociceptive effect induced by intraperitoneal administration of vitamin K2 (menatetrenone) in ICR mice.
Topics: Analgesics; Animals; Behavior, Animal; Bradykinin; Dinoprostone; Injections, Intraperitoneal; Injections, Spinal; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Substance P; Vitamin K; Vitamin K 2 | 2000 |
Chronic tobacco smoke exposure increases airway sensitivity to capsaicin in awake guinea pigs.
Topics: Administration, Inhalation; Airway Resistance; Animals; Bradykinin; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Capsaicin; Guinea Pigs; Histamine; Leukocyte Count; Lung; Male; Methacholine Chloride; Neurokinin A; Ovalbumin; Peptide Fragments; Smoking; Substance P; Wakefulness | 2001 |
Interactions of inflammatory mediators stimulating release of calcitonin gene-related peptide, substance P and prostaglandin E(2) from isolated rat skin.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Cyclooxygenase Inhibitors; Dinoprostone; Drug Combinations; Female; Flurbiprofen; Histamine; Hydrogen-Ion Concentration; In Vitro Techniques; Inflammation Mediators; Male; Nociceptors; Rats; Rats, Wistar; Serotonin; Skin; Substance P | 2001 |
Abnormal responses to endothelial agonists in Raynaud's phenomenon and scleroderma.
Topics: Blood Flow Velocity; Bradykinin; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Fingers; Humans; Male; Methacholine Chloride; Muscarinic Agonists; Nitroprusside; Raynaud Disease; Scleroderma, Systemic; Substance P; Vasodilator Agents | 2001 |
Effects of COX-1 and COX-2 inhibitors on eicosanoid biosynthesis and the release of substance P from the guinea-pig isolated perfused lung.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bradykinin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cysteine; Eicosanoids; Female; Guinea Pigs; Indomethacin; Inflammation Mediators; Isoenzymes; Leukotriene C4; Leukotrienes; Lung; Male; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Substance P; Sulfonamides | 2001 |
Omapatrilat, a dual angiotensin-converting enzyme and neutral endopeptidase inhibitor, prevents fatty streak deposit in apolipoprotein E-deficient mice.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Apolipoproteins E; Arteriosclerosis; Atrial Natriuretic Factor; Body Weight; Bradykinin; Cholesterol; Cholesterol, HDL; Drug Evaluation, Preclinical; Indans; Male; Mice; Mice, Knockout; Neprilysin; Propionates; Protease Inhibitors; Pyridines; Substance P; Thiazepines; Triglycerides | 2001 |
Inflammatory mediators potentiate ATP-gated channels through the P2X(3) subunit.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Animals; Bradykinin; Chlorides; Female; In Vitro Techniques; Kinetics; Membrane Potentials; Mutagenesis, Site-Directed; Neurons; Neuropeptides; Nociceptors; Oocytes; Protein Conformation; Protein Subunits; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Recombinant Fusion Proteins; Substance P; Tetradecanoylphorbol Acetate; Xenopus laevis | 2001 |
[No relation between angiotensin-converting enzyme (ACE) inhibitor-induced cough and ACE gene polymorphism, plasma bradykinin, substance P and ACE inhibitor concentration in Japanese patients].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Chronic Disease; Cough; Female; Humans; Hypertension; Indoles; Male; Middle Aged; Nephritis; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Substance P | 2001 |
Changes in paw oedema triggered via bradykinin B(1) and B(2) receptors in streptozotocin-diabetic rats.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Diabetes Mellitus, Experimental; Dinoprostone; Edema; Hindlimb; Hypoglycemic Agents; Insulin, Long-Acting; Male; Rats; Rats, Wistar; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Substance P; Time Factors | 2001 |
Effects of oophorectomy on functional properties of resistance arteries isolated from the cancellous bone of the rabbit femur.
Topics: Acetylcholine; Animals; Arteries; Bradykinin; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Female; Femur; Muscle Contraction; Muscle, Smooth, Vascular; Myography; Norepinephrine; Ovariectomy; Potassium; Rabbits; Substance P; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins | 2001 |
Perinatal vascular development.
Topics: Acetylcholine; Administration, Inhalation; Animals; Bradykinin; Extracorporeal Membrane Oxygenation; High-Frequency Ventilation; Humans; Infant, Newborn; Models, Animal; Nitric Oxide; Persistent Fetal Circulation Syndrome; Pulmonary Artery; Substance P; Swine; Vasodilator Agents | 2001 |
Perinatal development influences mechanisms of bradykinin-induced relaxations in pulmonary resistance and conduit arteries differently.
Topics: Acetylcholine; Analysis of Variance; Animals; Animals, Newborn; Bradykinin; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Proadifen; Pulmonary Artery; Substance P; Swine; Vascular Resistance; Vasodilator Agents | 2001 |
Chemokines and glycoprotein120 produce pain hypersensitivity by directly exciting primary nociceptive neurons.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Capsaicin; Cells, Cultured; Chemokines; Fluorescent Dyes; Ganglia, Spinal; HIV Envelope Protein gp120; Hyperalgesia; Inflammation; Intracellular Fluid; Male; Neurons; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, CCR4; Receptors, Chemokine; Receptors, CXCR4; RNA, Messenger; Substance P | 2001 |
Further investigations into the endothelium-dependent hyperpolarizing effects of bradykinin and substance P in porcine coronary artery.
Topics: Animals; Bicarbonates; Biological Factors; Bradykinin; Buffers; Coronary Vessels; Cromakalim; Endothelium, Vascular; Epoprostenol; Glyburide; HEPES; In Vitro Techniques; Indomethacin; Isotonic Solutions; Membrane Potentials; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroarginine; Peptides; Sodium Chloride; Substance P; Swine; Time Factors; Vasodilator Agents | 2001 |
Role of smooth muscle cells on endothelial cell cytosolic free calcium in porcine coronary arteries.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Bradykinin; Calcium; Cells, Cultured; Coronary Vessels; Cytosol; Dose-Response Relationship, Drug; Endothelium, Vascular; Fluorescent Dyes; In Vitro Techniques; Isometric Contraction; Microscopy, Confocal; Muscle, Smooth, Vascular; Potassium; Substance P; Swine; Vasodilation | 2001 |
Inhibitory effects of brefeldin A, a membrane transport blocker, on the bradykinin-induced hyperpolarization-mediated relaxation in the porcine coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Animals; Apamin; Biological Factors; Bradykinin; Brefeldin A; Calcium; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Male; Nitroarginine; Peptides; Potassium; Potassium Channel Blockers; Quaternary Ammonium Compounds; Substance P; Swine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2001 |
Hypoxia decreases lung neprilysin expression and increases pulmonary vascular leak.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Gene Expression Regulation, Enzymologic; Hypoxia; Lung; Male; Methionine; Microcirculation; Neprilysin; Neurokinin-1 Receptor Antagonists; Oxygen; Piperidines; Protease Inhibitors; Pulmonary Edema; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Specific Pathogen-Free Organisms; Substance P; Water | 2001 |
Coronary endothelial dysfunction in the early months after heart transplantation.
Topics: Bradykinin; Coronary Circulation; Endothelium, Vascular; Heart Transplantation; Humans; Postoperative Period; Substance P; Vascular Resistance | 2001 |
Assessment of microvascular endothelial function in human skin.
Topics: Acetylcholine; Adult; Bradykinin; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Iontophoresis; Laser-Doppler Flowmetry; Male; Methacholine Chloride; Microcirculation; Muscarinic Agonists; Reference Values; Skin; Substance P; Vasodilation; Vasodilator Agents | 2001 |
Isolation and properties of stachyrase A, a chymotrypsin-like serine proteinase from Stachybotrys chartarum.
Topics: alpha 1-Antichymotrypsin; alpha-Macroglobulins; Angiotensin I; Angiotensin II; Binding Sites; Bradykinin; Chymotrypsin; Collagen; Elastin; Neurotensin; Serine Endopeptidases; Serine Proteinase Inhibitors; Stachybotrys; Substance P; Tosylphenylalanyl Chloromethyl Ketone | 2002 |
Effect of neutral endopeptidase inhibitor on bradykinin-induced bronchoconstriction.
Topics: Animals; Benzamides; Bradykinin; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Dipeptides; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; Glycopeptides; Guinea Pigs; Indoles; Lung; Male; Metalloendopeptidases; Neurokinin A; Piperidines; Substance P | 2001 |
Effect of aspirin on vasodilation to bradykinin and substance P in patients with heart failure treated with ACE inhibitor.
Topics: Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Bradykinin; Confidence Intervals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Failure; Humans; Male; Middle Aged; Substance P; Vasodilation | 2002 |
Oxytocin stimulates cerebral blood flow in rainbow trout (Oncorhynchus mykiss) through a nitric oxide dependent mechanism.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Bradykinin; Cerebral Arteries; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Neurons; Nitric Oxide; Nitroarginine; Oncorhynchus mykiss; Oxytocin; Substance P; Telencephalon; Vasodilation | 2002 |
A cytosolic form of aminopeptidase P from Drosophila melanogaster: molecular cloning and characterization.
Topics: Amino Acid Sequence; Aminopeptidases; Animals; Base Sequence; Bradykinin; Brain; Catalytic Domain; Cloning, Molecular; Cytosol; DNA; Drosophila melanogaster; Humans; Manganese; Metalloendopeptidases; Molecular Sequence Data; Protein Binding; Sequence Homology, Amino Acid; Substance P; Substrate Specificity | 2002 |
Role of P(1) purinergic receptors in myocardial ischemia sensory transduction.
Topics: Adenosine; Animals; Bradykinin; Cells, Cultured; Electrophysiology; Female; Heart; Heart Ventricles; Male; Myocardial Ischemia; Neurons, Afferent; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction; Substance P; Swine | 2002 |
Characterization of sumatriptan-induced contractions in human isolated blood vessels using selective 5-HT(1B) and 5-HT(1D) receptor antagonists and in situ hybridization.
Topics: Adult; Aged; Animals; Blood Vessels; Bradykinin; Cerebral Arteries; CHO Cells; Coronary Vessels; Cricetinae; Female; Humans; In Situ Hybridization; In Vitro Techniques; Male; Meningeal Arteries; Middle Aged; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; RNA, Messenger; Saphenous Vein; Serotonin Antagonists; Substance P; Sumatriptan; Vasoconstriction; Vasoconstrictor Agents | 2002 |
Electrospray LC-MS/MS quantitation, stability, and preliminary pharmacokinetics of bradykinin antagonist polypeptide B201 (NSC 710295) in the mouse.
Topics: Animals; Bradykinin; Buffers; Chromatography, High Pressure Liquid; Drug Stability; Humans; Injections, Intravenous; Mass Spectrometry; Mice; Peptides; Reproducibility of Results; Solutions; Spectrometry, Mass, Electrospray Ionization; Substance P | 2002 |
PGE(2) increases release of substance P from renal sensory nerves by activating the cAMP-PKA transduction cascade.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Bradykinin; Calcitonin Gene-Related Peptide; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Kidney Pelvis; Male; Neurons, Afferent; Peripheral Nerves; Pressure; Rats; Rats, Sprague-Dawley; Signal Transduction; Substance P | 2002 |
Effect of cationic peptides on rat ileum muscle contraction and histamine release from rat peritoneal mast cells.
Topics: Animals; Benzalkonium Compounds; Bradykinin; Cations; Histamine Release; Ileum; Kallidin; Male; Mast Cells; Muscle Contraction; Muscle, Smooth; Peptides; Peritoneal Cavity; Rats; Rats, Wistar; Substance P | 2002 |
Charybdotoxin-sensitive small conductance K(Ca) channel activated by bradykinin and substance P in endothelial cells.
Topics: Animals; Apamin; Benzimidazoles; Bradykinin; Cells, Cultured; Charybdotoxin; Coronary Vessels; Endothelium, Vascular; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Small-Conductance Calcium-Activated Potassium Channels; Substance P; Swine | 2002 |
Neutral endopeptidase activity is not elevated in serum in children with cholestatic liver disease: a unique role of aminopeptidase-m in sequential hydrolysis of peptides.
Topics: Adolescent; Alagille Syndrome; Bradykinin; CD13 Antigens; Child; Chromatography, High Pressure Liquid; Enkephalins; Humans; Hydrolysis; Neprilysin; Peptides; Substance P | 2002 |
Characterization of PgPepO, a bacterial homologue of endothelin-converting enzyme-1.
Topics: Angiotensin I; Angiotensin II; Aspartic Acid Endopeptidases; Bacterial Proteins; Bradykinin; Chromatography, High Pressure Liquid; Endothelin-Converting Enzymes; Enzyme Activation; Enzyme Inhibitors; Glycopeptides; Humans; Hydrolysis; Inhibitory Concentration 50; Metalloendopeptidases; Neurotensin; Porphyromonas gingivalis; Substance P; Thiorphan | 2002 |
Marked bradykinin-induced tissue plasminogen activator release in patients with heart failure maintained on long-term angiotensin-converting enzyme inhibitor therapy.
Topics: Aged; Bradykinin; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Heart Failure; Humans; Infusions, Intravenous; Male; Middle Aged; Peptide Fragments; Plethysmography; Substance P; Tissue Plasminogen Activator; Vasomotor System | 2002 |
Relationships between pain-related mediators and both synovitis and joint pain in patients with internal derangements and osteoarthritis of the temporomandibular joint.
Topics: Adolescent; Adult; Aged; Arthralgia; Bradykinin; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Facial Pain; Female; Humans; Inflammation Mediators; Joint Dislocations; Leukotriene B4; Male; Middle Aged; Neurotransmitter Agents; Nociceptors; Osteoarthritis; Serotonin; Statistics, Nonparametric; Substance P; Synovial Fluid; Synovitis; Temporomandibular Joint Disorders | 2002 |
Endothelial dysfunction in murine model of systemic sclerosis: tight-skin mice 1.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Bradykinin; Calcium; Disease Models, Animal; Endothelium, Vascular; Iloprost; In Vitro Techniques; Isometric Contraction; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microscopy, Confocal; Nitric Oxide; Nitric Oxide Synthase; Scleroderma, Systemic; Skin; Substance P; Vasodilation; Vasodilator Agents | 2002 |
Hypercholesterolemia and hypertension have synergistic deleterious effects on coronary endothelial function.
Topics: Animals; Antioxidants; Ascorbic Acid; Bradykinin; Calcimycin; Coronary Artery Disease; Coronary Vessels; Cyclic GMP; Diet, Atherogenic; Endothelin-1; Endothelium, Vascular; Female; Hemodynamics; Hypercholesterolemia; Hypertension, Renovascular; Lipids; Nitric Oxide; Nitroprusside; Oxidative Stress; Renal Artery Obstruction; Renin; Substance P; Swine; Vasodilator Agents; Vitamin E | 2003 |
Endogenous nitric oxide release by vasoactive drugs monitored in exhaled air.
Topics: Acetylcholine; Aged; Aged, 80 and over; Animals; Bradykinin; Breath Tests; Dose-Response Relationship, Drug; Drug Monitoring; Endothelin-1; Endothelium, Vascular; Female; Humans; Injections, Intravenous; Luminescent Measurements; Male; Middle Aged; Models, Animal; Nitric Oxide; Nitroglycerin; Pulmonary Wedge Pressure; Sensitivity and Specificity; Substance P; Swine; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
Nerve growth factor (NGF) and glial cell line-derived neurotrophic factor (GDNF) regulate substance P release in adult spinal sensory neurons.
Topics: Animals; Bradykinin; Capsaicin; Female; Ganglia, Spinal; Glial Cell Line-Derived Neurotrophic Factor; Membrane Potentials; Nerve Growth Factor; Nerve Growth Factors; Neurons, Afferent; Potassium Chloride; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 2003 |
Angiotensin blocks substance P release from renal sensory nerves by inhibiting PGE2-mediated activation of cAMP.
Topics: Angiotensin II; Animals; Bradykinin; Cyclic AMP; Diet; Dinoprostone; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney Pelvis; Neurons, Afferent; Pertussis Toxin; Rats; Signal Transduction; Sodium; Substance P | 2003 |
The algogenic-induced nociceptive flexion test in mice: studies on sensitivity of the test and stress on animals.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Bites and Stings; Bradykinin; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Epoprostenol; Formaldehyde; Immobilization; Male; Mice; Pain; Pain Measurement; Peripheral Nervous System; Prostaglandins F; Reflex; Sensitivity and Specificity; Stress, Physiological; Substance P | 2003 |
Increased gastrin-releasing peptide (GRP) receptor expression in tumour cells confers sensitivity to [Arg6,D-Trp7,9,NmePhe8]-substance P (6-11)-induced growth inhibition.
Topics: Animals; Antineoplastic Agents; Bradykinin; Calcium; Carcinoma, Small Cell; Cell Division; DNA, Neoplasm; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fibroblasts; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Mice; Mice, Nude; Peptide Fragments; Rats; Receptors, Bombesin; Receptors, Neuropeptide; Substance P; Transplantation, Heterologous; Tumor Cells, Cultured; Vasopressins | 2003 |
A study of the cough reflex in idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents; Bradykinin; Brain-Derived Neurotrophic Factor; Bronchial Provocation Tests; Capsaicin; Case-Control Studies; Cough; Female; Forced Expiratory Volume; Humans; Inflammation; Leukocyte Count; Male; Nerve Growth Factor; Neutrophils; Prednisolone; Pulmonary Fibrosis; Sputum; Substance P; Total Lung Capacity; Treatment Outcome | 2003 |
Neutral endopeptidase (EC 3.4.24.11) downregulates the onset of intestinal inflammation in the nematode infected mouse.
Topics: Animals; Bradykinin; Intercellular Adhesion Molecule-1; Intestinal Diseases, Parasitic; Intestinal Mucosa; Intestines; Mice; Mice, Inbred C57BL; Mice, Knockout; Neprilysin; Substance P; Trichinella spiralis; Trichinellosis | 2003 |
A comparative study of bradykinin and substance P.
Topics: Bradykinin; Gastrointestinal Tract; Globulins; Substance P | 1955 |
[Differences in the effects of the polypeptide bradykinin and of substance P on the central nervous system].
Topics: Bradykinin; Central Nervous System; Globulins; Intestines; Peptides; Substance P | 1956 |
Assay of substance P on the fowl rectal caecum.
Topics: Acetylcholine; Atropine; Biological Assay; Bradykinin; Catecholamines; Cecum; Histamine; Peptides; Rectum; Scopolamine; Serotonin; Substance P; Tachyphylaxis | 1961 |
Actions of some peptides on bronchial muscle.
Topics: Angiotensin Amide; Angiotensins; Animals; Arginine Vasopressin; Bradykinin; Bronchi; Dogs; Guinea Pigs; Humans; Kallidin; Kallikreins; Lung; Male; Muscle, Smooth; Oxytocics; Oxytocin; Peptides; Prostate; Rabbits; Rats; Substance P; Trachea; Urethra; Vasopressins | 1962 |
A spectrum of pharmacological activity in some biologically active peptides.
Topics: Angiotensins; Animals; Arginine Vasopressin; Bradykinin; Female; Guinea Pigs; Ileum; Kallikreins; Muscle, Smooth; Oxytocics; Oxytocin; Peptides; Rats; Substance P; Vasopressins | 1962 |
Interaction of substance P and other smooth muscle stimulants with LSD-25 on the guinea pig ileum.
Topics: Acetylcholine; Bradykinin; Guinea Pigs; Ileum; Lysergic Acid Diethylamide; Muscle, Smooth; Peptides; Substance P | 1962 |
[STRUCTURE AND FUNCTION OF THE BIOLOGICALLY ACTIVE PEPTIDES: BRADYKININ, KALLIDIN, ANGIOTENSIN AND SUBSTANCE P].
Topics: Angiotensins; Bradykinin; Chemical Phenomena; Chemistry; Kallidin; Kallikreins; Peptides; Physiology; Research; Substance P | 1964 |
VASODILATING ACTION OF SUBSTANCE P IN THE HUMAN FOREARM.
Topics: Atropine; Autonomic Nerve Block; Blood Circulation; Blood Flow Velocity; Bradykinin; Forearm; Guanethidine; Heart Rate; Histamine H1 Antagonists; Humans; Injections, Intra-Arterial; Injections, Intravenous; Muscles; Peptides; Pharmacology; Plethysmography; Regional Blood Flow; Skin; Stellate Ganglion; Substance P; Vasodilation; Vasodilator Agents | 1965 |
The neuropeptide-degrading enzyme NL1 is expressed in specific neurons of mouse brain.
Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; Bradykinin; Brain; Central Nervous System; Chromatography, High Pressure Liquid; Embryo, Mammalian; Enkephalin, Leucine; Gene Expression; Gene Expression Regulation, Developmental; In Situ Hybridization; Intracellular Signaling Peptides and Proteins; Kinetics; Metalloendopeptidases; Mice; Neurons; Neuropeptide Y; Neuropeptides; Orexins; Peptides; Pituitary Gland; Recombinant Proteins; RNA, Messenger; Spinal Cord; Substance P | 2003 |
Role of endothelium-derived hyperpolarizing factor in human forearm circulation.
Topics: Acetylcholine; Adult; Biological Factors; Bradykinin; Female; Forearm; Humans; Infusions, Intra-Arterial; Male; Nicorandil; Nitroprusside; Potassium Channel Blockers; Regional Blood Flow; Substance P; Tetraethylammonium; Vascular Resistance; Vasodilation; Vasodilator Agents | 2003 |
Pro-inflammatory effect of quercetin by dual blockade of angiotensin converting-enzyme and neutral endopeptidase in vivo.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Injections, Intravenous; Male; Myocardium; Neprilysin; Organ Specificity; Pancreas; Peptidyl-Dipeptidase A; Quercetin; Rats; Rats, Wistar; Reference Values; Substance P; Tissue Distribution; Urinary Bladder | 2003 |
Surgery modifies cardiac sensory transduction.
Topics: Action Potentials; Adenosine; Animals; Animals, Newborn; Bradykinin; Heart Ventricles; Mechanotransduction, Cellular; Neurons, Afferent; Nodose Ganglion; Physical Stimulation; Sensory Receptor Cells; Substance P; Swine; Veratridine | 2003 |
Combined effect of bradykinin B2 and neurokinin-1 receptor activation on endothelial cell proliferation in acute synovitis.
Topics: Acute Disease; Animals; Bradykinin; Bradykinin B2 Receptor Antagonists; Cell Division; Endothelium; Models, Biological; Neurokinin-1 Receptor Antagonists; Rats; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Neurokinin-1; Substance P; Synovial Membrane; Synovitis | 2004 |
The effect of acute angiotensin-converting enzyme and neutral endopeptidase 24.11 inhibition on plasma extravasation in the rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Dose-Response Relationship, Drug; Lung; Male; Neprilysin; Peptidyl-Dipeptidase A; Plasma; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Neurokinin-1; Substance P; Thiorphan | 2004 |
Subtypes of vagal afferent C-fibres in guinea-pig lungs.
Topics: Action Potentials; Adenosine Triphosphate; Afferent Pathways; Animals; Bradykinin; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Electrophysiology; Ganglia; Guinea Pigs; Immunohistochemistry; In Vitro Techniques; Laryngeal Nerves; Lung; Male; Nerve Fibers, Unmyelinated; Neurofilament Proteins; Nodose Ganglion; Patch-Clamp Techniques; Physical Stimulation; Substance P; Trachea; Vagus Nerve | 2004 |
Improved PSD and CID on a MALDI TOFMS.
Topics: Angiotensin I; Angiotensin II; Bradykinin; Calibration; Electrochemistry; Ions; Peptides; Reference Values; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substance P | 2004 |
Mast cells and reactive oxygen species in citric acid-induced airway constriction.
Topics: Acridines; Administration, Inhalation; Animals; Bradykinin; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Citric Acid; Cromolyn Sodium; Drug Combinations; Guinea Pigs; Luminescent Measurements; Mast Cells; p-Methoxy-N-methylphenethylamine; Reactive Oxygen Species; Substance P | 2004 |
Pharmacology of the mouse-isolated cerebral artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Bradykinin; Calcium; Calcium Signaling; Canada; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelin-1; Extracellular Fluid; Fluorescence; Fura-2; Male; Membrane Potentials; Mice; Middle Cerebral Artery; Muscle Tonus; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Phenylephrine; Potassium; Potassium Chloride; Sodium Chloride; Substance P; Vasoconstriction; Vasodilation | 2004 |
Molecular basis of exopeptidase activity in the C-terminal domain of human angiotensin I-converting enzyme: insights into the origins of its exopeptidase activity.
Topics: Angiotensin I; Bradykinin; Computer Simulation; Evolution, Molecular; Exopeptidases; Humans; Kinetics; Mutation; Peptidyl-Dipeptidase A; Protein Binding; Protein Structure, Tertiary; Static Electricity; Substance P; Substrate Specificity | 2005 |
CB(1) cannabinoid receptor stimulation modulates transient receptor potential vanilloid receptor 1 activities in calcium influx and substance P Release in cultured rat dorsal root ganglion cells.
Topics: Animals; Bradykinin; Calcium; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Capsaicin; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Dose-Response Relationship, Drug; Dronabinol; Enzyme Induction; Enzyme Inhibitors; Ganglia, Spinal; Isoquinolines; Male; Piperidines; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; RNA, Messenger; Substance P; Sulfonamides; Time Factors | 2005 |
Zaltoprofen inhibits bradykinin-induced responses by blocking the activation of second messenger signaling cascades in rat dorsal root ganglion cells.
Topics: Animals; Benzopyrans; Bradykinin; Cells, Cultured; Dose-Response Relationship, Drug; Ganglia, Spinal; Propionates; Rats; Rats, Wistar; Second Messenger Systems; Substance P | 2005 |
The role of substance P and bradykinin in the cough reflex and bronchoconstriction in guinea-pigs.
Topics: Animals; Bradykinin; Bronchoconstriction; Citric Acid; Cough; Dose-Response Relationship, Drug; Glycopeptides; Guinea Pigs; Male; Oligopeptides; Protease Inhibitors; Reflex; Substance P; Time Factors | 2005 |
Bradykinin-induced, endothelium-dependent responses in porcine coronary arteries: involvement of potassium channel activation and epoxyeicosatrienoic acids.
Topics: 8,11,14-Eicosatrienoic Acid; Acetonitriles; Animals; Apamin; Bradykinin; Coronary Vessels; Endothelium, Vascular; In Vitro Techniques; Muscle Cells; Peptides; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Receptors, Eicosanoid; Substance P; Swine; Trityl Compounds | 2005 |
MALDI of individual biomolecule-containing airborne particles in an ion trap mass spectrometer.
Topics: Air; Bradykinin; Enkephalin, Leucine; Polylysine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substance P; Volatilization | 2005 |
Synergistic interactions between airway afferent nerve subtypes regulating the cough reflex in guinea-pigs.
Topics: Administration, Inhalation; Animals; Bradykinin; Bronchial Spasm; Capsaicin; Citric Acid; Cough; Guinea Pigs; Lung; Male; Mechanoreceptors; Microinjections; Nerve Fibers, Unmyelinated; Neurons, Afferent; Nociceptors; Reflex; Substance P; Tachykinins | 2005 |
Direct coupling of polymer-based microchip electrophoresis to online MALDI-MS using a rotating ball inlet.
Topics: Bombesin; Bradykinin; Cytochromes c; Electrophoresis, Microchip; Peptide Fragments; Polymethyl Methacrylate; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substance P; Trypsin | 2005 |
Colonic irritation in the rat sensitizes urinary bladder afferents to mechanical and chemical stimuli: an afferent origin of pelvic organ cross-sensitization.
Topics: Action Potentials; Afferent Pathways; Animals; Biomechanical Phenomena; Bradykinin; Capsaicin; Colon; Colonic Diseases; Denervation; Female; Pelvis; Physical Stimulation; Rats; Rats, Sprague-Dawley; Substance P; Trinitrobenzenesulfonic Acid; Urinary Bladder | 2006 |
Prostaglandin involvement in lung C-fiber activation by substance P in guinea pigs.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Asthma; Blood Pressure; Bradykinin; Capsaicin; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Guinea Pigs; Heart Rate; Indomethacin; Lung; Nerve Fibers, Unmyelinated; Prostaglandins; Respiratory Hypersensitivity; Substance P | 2006 |
Fragmentation of protonated peptide ions via interaction with metastable atoms.
Topics: Argon; Binding Sites; Bradykinin; Fibrinopeptide A; Insulin; Ions; Kinetics; Protons; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substance P | 2006 |
Substance P release evoked by capsaicin or potassium from rat cultured dorsal root ganglion neurons is conversely modulated with bradykinin.
Topics: Animals; Boron Compounds; Bradykinin; Capsaicin; Cells, Cultured; Cyclooxygenase 2; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Ganglia, Spinal; Inositol 1,4,5-Trisphosphate; MAP Kinase Kinase 1; MAP Kinase Signaling System; Neurons; Pain; Potassium; Potassium Chloride; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptor, Bradykinin B2; Signal Transduction; Substance P; Type C Phospholipases | 2006 |
Bradykinin is a potent pruritogen in atopic dermatitis: a switch from pain to itch.
Topics: Adult; Bradykinin; Cross-Over Studies; Dermatitis, Atopic; Female; Histamine; Histamine H1 Antagonists; Humans; Iontophoresis; Male; Pain; Pruritus; Serotonin; Single-Blind Method; Substance P; Urticaria; Water | 2006 |
Sensitization of pelvic nerve afferents and mast cell infiltration in the urinary bladder following chronic colonic irritation is mediated by neuropeptides.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Bradykinin; Capsaicin; Chronic Disease; Colitis; Cystitis, Interstitial; Female; Mast Cells; Nerve Endings; Nerve Fibers, Unmyelinated; Neurons, Afferent; Neuropeptides; Pelvis; Physical Stimulation; Rats; Rats, Sprague-Dawley; Substance P; Trinitrobenzenesulfonic Acid; Urethane; Urinary Bladder | 2007 |
Evidence of anti-inflammatory effects of Passiflora edulis in an inflammation model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Carrageenan; Disease Models, Animal; Female; Histamine; Inflammation; Interleukin-1beta; Leukocytes; Male; Mice; Nitric Oxide; Passiflora; Peroxidase; Phytotherapy; Plant Extracts; Pleurisy; Substance P; Tumor Necrosis Factor-alpha | 2007 |
Olopatadine attenuates the enhancement of capsaicin-evoked substance P release by bradykinin from cultured dorsal root ganglion neurons.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Capsaicin; Cells, Cultured; Dibenzoxepins; Dose-Response Relationship, Drug; Ganglia, Spinal; Neurons; Olopatadine Hydrochloride; Potassium; Rats; Rats, Wistar; Substance P; Time Factors | 2006 |
Prognostic factors in arthrocentesis of the temporomandibular joint: Comparison of bradykinin, leukotriene B4, prostaglandin E2, and substance P level in synovial fluid between successful and unsuccessful cases.
Topics: Adolescent; Adult; Aged; Bradykinin; Dinoprostone; Female; Humans; Joint Dislocations; Leukotriene B4; Male; Middle Aged; Osteoarthritis; Pain; Paracentesis; Prognosis; Statistics, Nonparametric; Substance P; Synovial Fluid; Temporomandibular Joint Disorders | 2007 |
Bradykinin- and substance P-induced edema formation in the hamster cheek pouch is tyrosine kinase dependent.
Topics: Animals; Bradykinin; Capillary Permeability; Cheek; Cricetinae; Dextrans; Disease Models, Animal; Edema; Fluorescein-5-isothiocyanate; Genistein; Male; Mesocricetus; Microcirculation; Microscopy, Video; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Signal Transduction; Substance P; Tyrphostins | 2007 |
Spinal mechanisms of antinociceptive action caused by diphenyl diselenide.
Topics: Analysis of Variance; Animals; Behavior, Animal; Benzene Derivatives; Bradykinin; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Inhibitory Concentration 50; Interleukin-1beta; Male; Mice; Organoselenium Compounds; Pain; Pain Measurement; Spinal Cord; Substance P; Tumor Necrosis Factor-alpha | 2007 |
Isotopic labelling of peptides and isotope ratio analysis using LC-ICP-MS: a preliminary study.
Topics: Bradykinin; Chromatography, Liquid; Europium; Isotopes; Mass Spectrometry; Substance P | 2008 |
Synaptobrevin I mediates exocytosis of CGRP from sensory neurons and inhibition by botulinum toxins reflects their anti-nociceptive potential.
Topics: Animals; Botulinum Toxins; Bradykinin; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Exocytosis; Membrane Potentials; Mice; Neurons, Afferent; Nociceptors; Pain; Potassium; Protein Isoforms; R-SNARE Proteins; Rats; SNARE Proteins; Substance P; Synaptic Vesicles; Synaptosomal-Associated Protein 25; Syntaxin 1; Trigeminal Ganglion | 2007 |
Anti-inflammatory evaluation of Solidago chilensis Meyen in a murine model of pleurisy.
Topics: Adenosine Deaminase; Animals; Anti-Inflammatory Agents; Bradykinin; Butanols; Carrageenan; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Flowers; Histamine; Inflammation; Interleukin-1beta; Leukocytes, Mononuclear; Male; Mice; Neutrophils; Peroxidase; Plant Extracts; Plant Leaves; Pleurisy; Rhizome; Solidago; Substance P; Tumor Necrosis Factor-alpha | 2007 |
Is dipeptidylpeptidase IV the missing link in angiotensin-converting enzyme inhibitor--induced angioedema?
Topics: Angioedema; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Enzyme Inhibitors; Humans; Hypertension; Neprilysin; Peptidyl-Dipeptidase A; Substance P | 2008 |
Dipeptidyl peptidase IV in angiotensin-converting enzyme inhibitor associated angioedema.
Topics: Adult; Aged; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Antigens; Bradykinin; Case-Control Studies; Dipeptidyl Peptidase 4; Female; Genetic Predisposition to Disease; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Substance P | 2008 |
Characterization of agonist-induced endothelium-dependent vasodilatory responses in the vascular bed of the equine digit.
Topics: Animals; Arteries; Bradykinin; Carbachol; Endothelium, Vascular; Female; Hindlimb; Horse Diseases; Horses; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Serotonin; Substance P; Vasodilation; Vasodilator Agents | 2008 |
Trapped-ion cell with improved DC potential harmonicity for FT-ICR MS.
Topics: Angiotensins; Bradykinin; Calibration; Cyclotrons; Endorphins; Fibrinopeptide A; Neurotensin; Peptides; Renin; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Substance P | 2008 |
Effect of a metabotropic glutamate receptor 5 antagonist, MPEP, on the nociceptive response induced by intrathecal injection of excitatory aminoacids, substance P, bradykinin or cytokines in mice.
Topics: Animals; Bradykinin; Cytokinins; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Injections, Spinal; Interleukin-1beta; Male; Mice; Nociceptors; Pain; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Substance P; Tumor Necrosis Factor-alpha | 2008 |
Role of substance P and bradykinin in acute pancreatitis induced by secretory phospholipase A2.
Topics: Acute Disease; Amylases; Animals; Bradykinin; Bradykinin B2 Receptor Antagonists; Disease Models, Animal; Lung; Male; Neurokinin-1 Receptor Antagonists; Pancreas; Pancreatitis; Peroxidase; Phospholipases A2, Secretory; Piperidines; Pneumonia; Quinuclidines; Rats; Rats, Wistar; Receptor, Bradykinin B2; Receptors, Neurokinin-1; Substance P; Tumor Necrosis Factor-alpha | 2008 |
Endothelium-derived hyperpolarizing factor mediated relaxations in pig coronary arteries do not involve Gi/o proteins.
Topics: Animals; Apamin; Biological Factors; Bradykinin; Calcimycin; Charybdotoxin; Coronary Vessels; Dinoprost; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Hemostatics; Ionophores; Ketanserin; Muscle Relaxation; Neurotoxins; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Peptide Fragments; Pertussis Toxin; Serotonin; Serotonin Antagonists; Substance P; Sus scrofa; Thrombin; Vasodilator Agents | 2008 |
Tumor bearing decreases systemic acute inflammation in rats--role of mast cell degranulation.
Topics: Animals; Bradykinin; Capillary Permeability; Capsaicin; Carrageenan; Cell Degranulation; Dextrans; Edema; Histamine; Inflammation; Mast Cells; Neoplasm Transplantation; Neoplasms; Neutrophil Activation; Neutrophil Infiltration; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar; Serotonin; Substance P | 2009 |
Metastable atom-activated dissociation mass spectrometry: leucine/isoleucine differentiation and ring cleavage of proline residues.
Topics: Angiotensin II; Bradykinin; Cholecystokinin; Dipeptides; Fibrinopeptide B; Isoleucine; Leucine; Mass Spectrometry; Peptide Fragments; Phosphoproteins; Proline; Proteins; Substance P | 2009 |
Differential ion mobility separations of peptides with resolving power exceeding 50.
Topics: Bradykinin; Intercellular Signaling Peptides and Proteins; Mass Spectrometry; Peptides; Substance P | 2010 |
Anti-inflammatory evaluation of Coronopus didymus in the pleurisy and paw oedema models in mice.
Topics: Adenosine Deaminase; Animals; Anti-Inflammatory Agents; Bradykinin; Brazil; Carrageenan; Edema; Histamine; Inflammation; Leukocyte Count; Leukocytes; Mice; Neutrophils; Nitric Oxide; Peroxidase; Plant Leaves; Pleurisy; Rats; Substance P | 2010 |
Mediator release of neuropeptides after nasal provocation in perennial allergic rhinitis patients.
Topics: Allergens; Animals; Bradykinin; Case-Control Studies; Female; Humans; Male; Nasal Lavage Fluid; Nasal Provocation Tests; Neuropeptides; Pyroglyphidae; Rhinitis, Allergic, Perennial; Statistics, Nonparametric; Substance P; Young Adult | 2010 |
Circulating neprilysin clears brain amyloid.
Topics: Amyloid beta-Peptides; Animals; Blood Pressure; Blood-Brain Barrier; Bradykinin; Brain; Brain Chemistry; Dependovirus; Humans; Mice; Neprilysin; Substance P | 2010 |
Carbamino group formation with peptides and proteins studied by mass spectrometry.
Topics: Amines; Angiotensin II; Animals; Bradykinin; Carbon Dioxide; Humans; Hydrogen-Ion Concentration; Insulin; Peptides; Spectrometry, Mass, Electrospray Ionization; Substance P | 2010 |
A-995662 [(R)-8-(4-methyl-5-(4-(trifluoromethyl)phenyl)oxazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol], a novel, selective TRPV1 receptor antagonist, reduces spinal release of glutamate and CGRP in a rat knee joint pain model.
Topics: Analysis of Variance; Animals; Bradykinin; Calcitonin Gene-Related Peptide; Glutamic Acid; Osteoarthritis, Knee; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Tetrahydronaphthalenes; TRPV Cation Channels | 2010 |
Sensitized peripheral nociception in experimental diabetes of the rat.
Topics: Action Potentials; Animals; Behavior, Animal; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Diabetes Mellitus, Experimental; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; In Vitro Techniques; Male; Nerve Fibers; Nociceptors; Pain Measurement; Pain Threshold; Rats; Reaction Time; Sciatic Nerve; Skin; Streptozocin; Substance P | 2010 |
E. coli lipopolysaccharide attenuates adenosine A(1) receptor-mediated increase in plasma exudation from the hamster cheek pouch.
Topics: Animals; Bradykinin; Cheek; Cricetinae; Escherichia coli; Lipopolysaccharides; Mesocricetus; Microcirculation; Plasma; Receptor, Adenosine A1; Substance P | 2011 |
DPP-4 inhibitors and angioedema: a cause for concern?
Topics: Angioedema; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypertension; Product Surveillance, Postmarketing; Substance P | 2011 |
Gi-coupled γ-aminobutyric acid-B receptors cross-regulate phospholipase C and calcium in airway smooth muscle.
Topics: Baclofen; Bradykinin; Calcium; Cells, Cultured; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Humans; Inositol Phosphates; Lung; Muscimol; Muscle Contraction; Muscle, Smooth; Myocytes, Smooth Muscle; Receptors, GABA-A; Receptors, GABA-B; Substance P; Type C Phospholipases; Xanthenes | 2011 |
Dragon's blood inhibits chronic inflammatory and neuropathic pain responses by blocking the synthesis and release of substance P in rats.
Topics: Analgesics, Non-Narcotic; Animals; Bradykinin; Capsaicin; Carrageenan; Chalcone; Cyclooxygenase 2; Drugs, Chinese Herbal; Ganglia, Spinal; Inflammation; Male; Pain; Plant Extracts; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Sciatic Nerve; Substance P; Tachykinins | 2012 |
Comparative study of the anti-edematogenic effects of anethole and estragole.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Anti-Inflammatory Agents; Bradykinin; Carrageenan; Edema; Histamine; Mice; Nitric Oxide; Serotonin; Substance P; Tumor Necrosis Factor-alpha | 2012 |
In defense of WHO's blood donation policy--response.
Topics: Abdomen; Animals; Blood Donors; Bradykinin; Female; Guidelines as Topic; Humans; Male; Neurons, Afferent; Reimbursement, Incentive; Serotonin; Substance P | 2013 |
Involvement of substance p/neurokinin-1 receptor in the analgesic and anticancer activities of minimally toxic fraction from the traditional Chinese medicine Liu-Shen-Wan in vitro.
Topics: Analgesics; Antineoplastic Agents; Apoptosis; Bradykinin; Complex Mixtures; Dose-Response Relationship, Drug; Down-Regulation; Ganglia, Spinal; Hep G2 Cells; Hepatoblastoma; Humans; Liver Neoplasms; Medicine, Chinese Traditional; Mitochondria; Neoplasms; Pain; Phytotherapy; Receptors, Neurokinin-1; Substance P | 2014 |
Bradykinin regulates the expression of claudin-5 in brain microvascular endothelial cells via calcium-induced calcium release.
Topics: Animals; Benzimidazoles; Bradykinin; Caffeine; Calcium; Cerebral Cortex; Claudin-5; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation; Histamine; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Rats; Rats, Wistar; Serotonin; Substance P; Vasodilator Agents | 2014 |
Defining modulatory inputs into CNS neuronal subclasses by functional pharmacological profiling.
Topics: Animals; Bradykinin; Brain Stem; Calcium; Cells, Cultured; Central Nervous System; Cluster Analysis; Female; Ganglia, Spinal; Histamine; Imaging, Three-Dimensional; Male; Mice; Mice, Inbred C57BL; Nerve Net; Neurons; Receptors, Cholinergic; Receptors, Glutamate; Respiratory Center; Substance P | 2014 |
Algogenic substances and metabolic status in work-related Trapezius Myalgia: a multivariate explorative study.
Topics: Adult; Bradykinin; Case-Control Studies; Female; Glutamic Acid; Humans; Interleukin-6; L-Lactate Dehydrogenase; Microdialysis; Multivariate Analysis; Myalgia; Pain Threshold; Peptide Fragments; Potassium; Procollagen; Pyruvic Acid; Regional Blood Flow; Serotonin; Substance P; Superficial Back Muscles | 2014 |
3D ToF-SIMS Analysis of Peptide Incorporation into MALDI Matrix Crystals with Sub-micrometer Resolution.
Topics: Bradykinin; Coumaric Acids; Crystallization; Gentisates; Imaging, Three-Dimensional; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrometry, Mass, Secondary Ion; Substance P; Vasopressins | 2016 |
Development of a spontaneously active dorsal root ganglia assay using multiwell multielectrode arrays.
Topics: Action Potentials; Animals; Bradykinin; Calcium Channel Blockers; Capsaicin; Cells, Cultured; Embryo, Mammalian; Female; Ganglia, Spinal; Hot Temperature; Membrane Transport Modulators; Mibefradil; Neurons; Rats; Rats, Sprague-Dawley; Sensory System Agents; Sodium Channel Blockers; Sodium Chloride; Substance P; Tetrodotoxin | 2016 |
Bidirectional communication between sensory neurons and osteoblasts in an in vitro coculture system.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Cell Communication; Cell Line; Coculture Techniques; Exocytosis; Ganglia, Spinal; Glutamic Acid; Humans; Mice, Inbred BALB C; Neurotransmitter Agents; Osteoblasts; Sensory Receptor Cells; Signal Transduction; Substance P | 2017 |
Nerve growth factor derivative NGF61/100 promotes outgrowth of primary sensory neurons with reduced signs of nociceptive sensitization.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Calcium; Ganglia, Spinal; Gene Expression Profiling; Humans; Nerve Growth Factor; Pain; Peptide Fragments; Primary Cell Culture; Rats; Receptors, Bradykinin; Sensory Receptor Cells; Substance P; TRPV Cation Channels; Up-Regulation | 2017 |
Spinal neuropeptide modulation, functional assessment and cartilage lesions in a monosodium iodoacetate rat model of osteoarthritis.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Cartilage Diseases; Disease Models, Animal; Female; Iodoacetic Acid; Neuropeptides; Nociception; Osteoarthritis; Pain Threshold; Rats, Sprague-Dawley; Somatostatin; Spinal Cord; Stifle; Substance P | 2017 |
Naturally Occurring Missense MRGPRX2 Variants Display Loss of Function Phenotype for Mast Cell Degranulation in Response to Substance P, Hemokinin-1, Human β-Defensin-3, and Icatibant.
Topics: Animals; beta-Defensins; Bradykinin; Cell Degranulation; Cell Line, Tumor; Humans; Ligands; Loss of Function Mutation; Mast Cells; Mutation, Missense; Nerve Tissue Proteins; Neuropeptides; Phenotype; Rats; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Substance P; Tachykinins | 2018 |
Mycoplasma hyopneumoniae surface-associated proteases cleave bradykinin, substance P, neurokinin A and neuropeptide Y.
Topics: Adhesins, Bacterial; Aminopeptidases; Animals; Bacterial Proteins; Bradykinin; Immunity, Innate; Metalloendopeptidases; Mycoplasma hyopneumoniae; Neurokinin A; Neuropeptide Y; Proteomics; Substance P; Swine; Trypsin | 2019 |
Labeled substance P as a neuropeptide reporter substance for enzyme activity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Chromatography, Thin Layer; Humans; Neuropeptides; Peptidyl-Dipeptidase A; Substance P | 2020 |
Neurolysin substrates bradykinin, neurotensin and substance P enhance brain microvascular permeability in a human in vitro model.
Topics: Blood-Brain Barrier; Bradykinin; Brain; Capillary Permeability; Cell Line; Endothelial Cells; Humans; In Vitro Techniques; Neurotensin; Substance P; Vascular Endothelial Growth Factor A | 2021 |
Substance P Serum Degradation in Complex Regional Pain Syndrome - Another Piece of the Puzzle?
Topics: Bradykinin; Complex Regional Pain Syndromes; Humans; Peptide Hydrolases; Peptidyl-Dipeptidase A; Substance P | 2022 |