Page last updated: 2024-08-23

substance p and baclofen

substance p has been researched along with baclofen in 62 studies

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199039 (62.90)18.7374
1990's14 (22.58)18.2507
2000's5 (8.06)29.6817
2010's3 (4.84)24.3611
2020's1 (1.61)2.80

Authors

AuthorsStudies
Konishi, S; Otsuka, M1
Costa, E; Guidotti, A; Naik, SR1
Burgis, V; Edwards, JD; Frederickson, RC; Harrell, CE1
Aghajanian, GK; Guyenet, PG1
Biswas, B; Carlsson, A; Lindqvist, M1
Yau, WM1
Fotherby, KJ; Morrish, NJ; Ryall, RW1
Ben-Ari, Y; Henry, JL1
Phillis, JW1
Del Bianco, E; Maggi, CA; Santicioli, P; Tramontana, M1
Benoliel, JJ; Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Mauborgne, A; Pohl, M1
Jones, AJ; Keen, P; Ray, NJ1
Couture, R; De Champlain, J; Hasséssian, H; Prat, A1
Taniyama, K1
Persson, B; Rubenson, A; Sillén, U1
Robertson, G; Sawynok, J1
Hwang, AS; Wilcox, GL2
Akagi, H; Yanagisawa, M1
Beal, MF; Ferrante, RJ; Kowall, NW; Martin, JB; Swartz, KJ1
Aanonsen, LM; Wilcox, GL1
Inoki, R; Lin, JG; Tsai, HY1
Barnes, PJ; Belvisi, MG; Ichinose, M1
Sawynok, J1
Tsai, HY2
Chahl, LA; Walker, SB1
Kudo, T1
Kanazawa, I; Yoshida, M1
Ganten, D; Rettig, R; Rockhold, RW; Unger, T; Yukimura, T1
Sears, M; Soloway, MR; Stjernschantz, J1
Otsuka, M; Yanagisawa, M1
Ajioka, H; Fukuda, H; Kudo, Y1
Kato, T; Nagatsu, T; Togari, A1
Abe, H; Ogata, N2
Fujiwara, M; Muramatsu, I; Sakakibara, Y; Ueda, N1
Fujisawa, K; Ito, Y1
Havlicek, V; Kato, N; LaBella, FS; Sawynok, J1
Couture, R; Cuello, AC1
Leo, A; Marano, E; Steardo, L1
Moochhala, SM; Pillay, DJ; Sawynok, J1
Inoki, R; Iwatsubo, K; Maeda, S; Tsai, HY1
Jenner, P; Jolkkonen, J; Marsden, CD1
Bowery, NG; Constanti, A; Libri, V; Malcangio, M; Teoh, H1
Bowery, NG; Malcangio, M1
Ayata, C; Cutrer, FM; Lee, WS; Limmroth, V; Moskowitz, MA; Waeber, C; Yu, X1
Bowery, NG; Malcangio, M; Teoh, H1
Cody, C; Jones, RS; Maubach, KA1
Malcangio, M; Tomlinson, DR1
Bunnett, NW; Grady, EF; Marvizón, JC; Mayer, EA; Stefani, E1
Grillner, S; Parker, D; Svensson, E; Ullström, M1
Bengtson, CP; Osborne, PB1
Bradley, RM; Koga, T1
Lu, Y; Westlund, KN1
Ben Smail, D; Bussel, B; Denys, P; Hugeron, C1
Drew, GM; Mitchell, VA; Vaughan, CW1
Castro, AR; Lima, D; Pinto, M; Tavares, I1
Hjelmstad, GO; Margolis, EB; Xia, YF1
Chen, W; Marvizón, JC; Zhang, G1
Emala, CW; Masaki, E; Mizuta, F; Mizuta, K; Panettieri, RA; Xu, D1
Doi, M; Irifune, M; Kanematsu, T; Morioka, N; Mukai, A; Nakata, Y; Ogawa, Y; Oue, K; Sakai, N; Shimizu, Y; Yoshida, M1

Reviews

1 review(s) available for substance p and baclofen

ArticleYear
[GABAergic neurons in the mammalian intestine].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 85, Issue:5

    Topics: Animals; Autonomic Fibers, Postganglionic; Autoradiography; Baclofen; Calcium; Digestive System; gamma-Aminobutyric Acid; Gastrointestinal Motility; Glutamate Decarboxylase; Guinea Pigs; Histocytochemistry; Humans; In Vitro Techniques; Muscimol; Myenteric Plexus; Potassium; Rabbits; Rats; Receptors, GABA-A; Substance P; Synaptic Transmission; Vasoactive Intestinal Peptide

1985

Trials

1 trial(s) available for substance p and baclofen

ArticleYear
Efficacy of baclofen in trigeminal neuralgia and some other painful conditions. A clinical trial.
    European neurology, 1984, Volume: 23, Issue:1

    Topics: Adult; Amputation Stumps; Baclofen; Carbamazepine; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Neuralgia; Phenytoin; Radiculopathy; Substance P; Tabes Dorsalis; Trigeminal Neuralgia

1984

Other Studies

60 other study(ies) available for substance p and baclofen

ArticleYear
Substance P and excitatory transmitter of primary sensory neurons.
    Cold Spring Harbor symposia on quantitative biology, 1976, Volume: 40

    Topics: Amino Acids; Animals; Animals, Newborn; Baclofen; Dose-Response Relationship, Drug; Drug Interactions; Glutamates; In Vitro Techniques; Membrane Potentials; Motor Neurons; Neurons; Neurons, Afferent; Neurotransmitter Agents; Picrotoxin; Rats; Reflex; Spinal Cord; Spinal Nerve Roots; Stimulation, Chemical; Substance P; Synapses; Synaptic Transmission

1976
Central GABA receptor agonists: comparison of muscimol and baclofen.
    Neuropharmacology, 1976, Volume: 15, Issue:8

    Topics: Aminobutyrates; Animals; Anticonvulsants; Baclofen; Cerebellum; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Harmaline; Isoniazid; Male; Motor Activity; Muscle Tonus; Mycotoxins; Oxazoles; Phenobarbital; Quaternary Ammonium Compounds; Rats; Receptors, Drug; Strychnine; Substance P

1976
Dual actions of substance P on nociception: possible role of endogenous opioids.
    Science (New York, N.Y.), 1978, Mar-24, Volume: 199, Issue:4335

    Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Mice; Naloxone; Nociceptors; Receptors, Opioid; Structure-Activity Relationship; Substance P

1978
ACh, substance P and met-enkephalin in the locus coeruleus: pharmacological evidence for independent sites of action.
    European journal of pharmacology, 1979, Feb-01, Volume: 53, Issue:4

    Topics: Acetylcholine; Animals; Baclofen; Endorphins; Enkephalins; Locus Coeruleus; Male; Naloxone; Parasympatholytics; Parasympathomimetics; Rats; Receptors, Cholinergic; Substance P; Synaptic Transmission

1979
Influence of GABA and GABA-like drugs on monoaminergic mechanisms.
    Advances in biochemical psychopharmacology, 1977, Volume: 16

    Topics: 5-Hydroxytryptophan; Aminobutyrates; Animals; Baclofen; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraventricular; Norepinephrine; Rats; Receptors, Drug; Serotonin; Substance P

1977
Effect of substance P on intestinal muscle.
    Gastroenterology, 1978, Volume: 74, Issue:2 Pt 1

    Topics: Acetylcholine; Animals; Atropine; Autonomic Fibers, Postganglionic; Baclofen; Ceruletide; Dose-Response Relationship, Drug; Electrophysiology; Female; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Kinetics; Muscle, Smooth; Neurons; Substance P; Tetrodotoxin

1978
Is Lioresal (Baclofen) an antagonist of substance P?
    Brain research, 1976, Aug-20, Volume: 113, Issue:1

    Topics: Aminobutyrates; Animals; Baclofen; Gastrointestinal Motility; Guinea Pigs; Ileum; Substance P

1976
Actions of the p-chlorophenyl derivative of GABA, Lioresal, on nociceptive and non-nociceptive units in the spinal cord of the cat.
    Brain research, 1976, Dec-03, Volume: 117, Issue:3

    Topics: Aminobutyrates; Animals; Baclofen; Cats; Depression, Chemical; Spinal Cord; Substance P

1976
Is beta-(4-chlorophenyl)-GABA a specific antagonist of substance P on cerebral cortical neurons?
    Experientia, 1976, May-15, Volume: 32, Issue:5

    Topics: Acetylcholine; Action Potentials; Aminobutyrates; Animals; Baclofen; Cerebral Cortex; Glutamates; Male; Neurons; Pyramidal Tracts; Rats; Stimulation, Chemical; Substance P

1976
Adenosine inhibits action potential-dependent release of calcitonin gene-related peptide- and substance P-like immunoreactivities from primary afferents in rat spinal cord.
    Neuroscience letters, 1992, Sep-14, Volume: 144, Issue:1-2

    Topics: Action Potentials; Adenosine; Animals; Baclofen; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; In Vitro Techniques; Male; Neurons, Afferent; Rats; Rats, Wistar; Spinal Cord; Substance P; Tetrodotoxin

1992
gamma-Aminobutyric acid, through GABAA receptors, inhibits the potassium-stimulated release of calcitonin gene-related peptide- but not that of substance P-like material from rat spinal cord slices.
    Brain research, 1992, Jun-26, Volume: 583, Issue:1-2

    Topics: Animals; Baclofen; Bicuculline; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Substance P

1992
GABAB receptor modulation of the release of substance P from capsaicin-sensitive neurones in the rat trachea in vitro.
    British journal of pharmacology, 1991, Volume: 102, Issue:4

    Topics: Animals; Baclofen; Bicuculline; Capsaicin; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neurons; Potassium; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substance P; Taurine; Trachea

1991
Regulation of cardiovascular sympathetic neurons by substance P and gamma-aminobutyric acid in the rat spinal cord.
    European journal of pharmacology, 1991, Sep-04, Volume: 202, Issue:1

    Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Capsaicin; Cardiovascular Physiological Phenomena; Cardiovascular System; Catecholamines; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Heart Rate; Injections, Spinal; Male; Muscimol; Neurons; Neuropeptide Y; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Substance P; Sympathetic Nervous System

1991
Central effects of baclofen on the L-dopa induced hyperactive urinary bladder of the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 330, Issue:3

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Injections, Intraventricular; Levodopa; Male; Naloxone; Rats; Rats, Inbred Strains; Substance P; Urinary Bladder

1985
Desensitization to substance P following intrathecal injection. A technique for investigating the role of substance P in nociception.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 331, Issue:2-3

    Topics: Animals; Baclofen; Injections, Spinal; Male; Morphine; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds; Substance P; Time Factors

1985
Intradermal hypertonic saline-induced behavior as a nociceptive test in mice.
    Life sciences, 1986, Jun-30, Volume: 38, Issue:26

    Topics: Animals; Anti-Inflammatory Agents; Baclofen; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intradermal; Injections, Spinal; Male; Mice; Morphine; Nalorphine; Pain; Pentazocine; Saline Solution, Hypertonic; Sodium Chloride; Spinal Cord; Substance P

1986
GABAergic modulation of a substance P-mediated reflex of slow time course in the isolated rat spinal cord.
    British journal of pharmacology, 1987, Volume: 91, Issue:1

    Topics: Animals; Baclofen; Bicuculline; Diazepam; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Substance P

1987
Systemic approaches to modifying quinolinic acid striatal lesions in rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:10

    Topics: 2-Amino-5-phosphonovalerate; Allopurinol; Amino Acids; Animals; Antioxidants; Baclofen; Corpus Striatum; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Huntington Disease; Ketamine; Male; Neuropeptide Y; Nimodipine; Peptides; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Substance P; Taurine; Valine

1988
Baclofen, gamma-aminobutyric acidB receptors and substance P in the mouse spinal cord.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3

    Topics: Amino Acids; Amino Acids, Neutral; Analgesics; Animals; Baclofen; Dose-Response Relationship, Drug; Mice; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Substance P

1989
Muscimol, gamma-aminobutyric acidA receptors and excitatory amino acids in the mouse spinal cord.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3

    Topics: Analgesia; Animals; Aspartic Acid; Baclofen; Behavior, Animal; Bicuculline; Kainic Acid; Male; Mice; Muscimol; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, GABA-A; Spinal Cord; Substance P

1989
Further evidence for possible analgesic mechanism of electroacupuncture: effects on neuropeptides and serotonergic neurons in rat spinal cord.
    Japanese journal of pharmacology, 1989, Volume: 49, Issue:2

    Topics: Acupuncture Therapy; Analgesia, Epidural; Animals; Baclofen; Electric Stimulation; Enkephalin, Methionine; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds; Serotonin; Spinal Cord; Substance P

1989
Modulation of non-adrenergic, non-cholinergic neural bronchoconstriction in guinea-pig airways via GABAB-receptors.
    British journal of pharmacology, 1989, Volume: 97, Issue:4

    Topics: Animals; Atropine; Autonomic Nervous System; Baclofen; Bicuculline; Blood Pressure; Bronchi; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Phentolamine; Propranolol; Receptors, GABA-A; Substance P; Time Factors; Vagus Nerve

1989
GABAergic mechanisms in antinociception.
    Progress in neuro-psychopharmacology & biological psychiatry, 1984, Volume: 8, Issue:4-6

    Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Analgesics; Animals; Baclofen; Bicuculline; Central Nervous System; gamma-Aminobutyric Acid; Isoxazoles; Mice; Muscimol; Pain; Rats; Stereoisomerism; Substance P; Synaptic Transmission; Vigabatrin

1984
Effect of neuroactive peptides on labeled 5-hydroxytryptamine release from rat spinal cord.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1984, Volume: 8, Issue:2

    Topics: Animals; Baclofen; beta-Endorphin; Endorphins; Enkephalin, Methionine; Male; Naloxone; Neuropeptides; Neurotensin; Pain; Rats; Rats, Inbred Strains; Secretory Rate; Serotonin; Somatostatin; Spinal Cord; Substance P

1984
The mechanism of enhancement of the neurogenic oedema response by baclofen.
    European journal of pharmacology, 1980, Mar-07, Volume: 62, Issue:1

    Topics: Animals; Baclofen; Blood Pressure; Drug Interactions; Edema; Exudates and Transudates; Injections, Intravenous; Injections, Subcutaneous; Male; Neurons; Rats; Serotonin; Substance P

1980
[Mechanism of substance P-induced salivary secretion in the rat: effect of substance P on autonomic nervous system and prostaglandin synthesis (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1980, Volume: 76, Issue:2

    Topics: Amylases; Animals; Autonomic Nervous System; Baclofen; Brain; Injections, Intravenous; Injections, Intraventricular; Male; Parasympatholytics; Prostaglandins; Prostaglandins E; Rats; Saliva; Stimulation, Chemical; Substance P; Sympatholytics; Sympathomimetics; Synaptosomes; Time Factors

1980
Electrophysiological evidence for the existence of excitatory fibres in the caudato-nigral pathway in the cat.
    Neuroscience letters, 1980, Volume: 20, Issue:3

    Topics: Animals; Atropine; Baclofen; Cats; Caudate Nucleus; Electrophysiology; gamma-Aminobutyric Acid; Neural Pathways; Picrotoxin; Reaction Time; Substance P; Substantia Nigra

1980
Blood pressure and heart rate responses to centrally administered substance P are increased in spontaneously hypertensive rats.
    Clinical science (London, England : 1979), 1980, Volume: 59 Suppl 6

    Topics: Angiotensin II; Animals; Baclofen; Blood Pressure; Denervation; Dose-Response Relationship, Drug; Female; Heart Rate; Hypertension; Injections, Intraventricular; Male; Pressoreceptors; Rats; Substance P

1980
The miotic effect of substance P on the isolated rabbit iris.
    Investigative ophthalmology & visual science, 1981, Volume: 20, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Baclofen; Dose-Response Relationship, Drug; Egtazic Acid; Indomethacin; Iris; Male; Miotics; Rabbits; Substance P

1981
The effects of substance P and baclofen on motoneurones of isolated spinal cord of the newborn rat.
    The Journal of experimental biology, 1980, Volume: 89

    Topics: Action Potentials; Animals; Animals, Newborn; Baclofen; Calcium; gamma-Aminobutyric Acid; Glutamates; Glycine; In Vitro Techniques; Motor Neurons; Perfusion; Rats; Spinal Cord; Substance P

1980
Antagonistic action of baclofen on substance P-induced depolarization in the isolated spinal cord of the frog.
    General pharmacology, 1981, Volume: 12, Issue:3

    Topics: Animals; Baclofen; Calcium; In Vitro Techniques; Magnesium; Rana catesbeiana; Spinal Cord; Substance P; Synaptic Transmission

1981
Effect of substance P C-terminal heptapeptide on amylase release in rat parotid gland.
    Archives of oral biology, 1980, Volume: 25, Issue:8-9

    Topics: Amylases; Animals; Baclofen; Male; Parotid Gland; Peptide Fragments; Rats; Substance P

1980
Further support for the postsynaptic action of substance P and its blockade with baclofen in neurons of the guinea-pig hypothalamus in vitro.
    Experientia, 1981, Jul-15, Volume: 37, Issue:7

    Topics: Acetylcholine; Action Potentials; Animals; Baclofen; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hypothalamus; In Vitro Techniques; Male; Neurons; Substance P; Synapses

1981
Noncholinergic, nonadrenergic contraction and substance P in rabbit iris sphincter muscle.
    Japanese journal of pharmacology, 1981, Volume: 31, Issue:6

    Topics: Acetylcholine; Animals; Baclofen; Capsaicin; Cold Temperature; Electric Stimulation; Female; In Vitro Techniques; Iris; Male; Muscle Contraction; Rabbits; Reserpine; Substance P; Sympathectomy

1981
The effects of substance P on smooth muscle cells and on neuro-effector transmission in the guinea-pig ileum.
    British journal of pharmacology, 1982, Volume: 76, Issue:2

    Topics: Animals; Baclofen; Electrophysiology; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth; Neuroeffector Junction; Potassium Chloride; Substance P; Synaptic Transmission

1982
Lack of effect of baclofen on substance P and somatostatin release from the spinal cord in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 319, Issue:1

    Topics: Animals; Baclofen; In Vitro Techniques; Male; Perfusion; Rats; Rats, Inbred Strains; Somatostatin; Spinal Cord; Substance P

1982
Neuropharmacology in the brain slice: effects of substance P on neurons in the guinea-pig hypothalamus.
    Comparative biochemistry and physiology. C: Comparative pharmacology, 1982, Volume: 72, Issue:2

    Topics: Animals; Baclofen; Electrophysiology; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hypothalamus; In Vitro Techniques; Male; Neurons; Substance P

1982
Studies on the trigeminal antidromic vasodilatation and plasma extravasation in the rat.
    The Journal of physiology, 1984, Volume: 346

    Topics: Animals; Baclofen; Capillary Permeability; Cimetidine; Evoked Potentials; Female; Indomethacin; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Substance P; Sympatholytics; Trigeminal Nerve; Vasodilation

1984
Further evidence for the possible relationship between neuropeptides and serotonergic neurones in rat spinal cord.
    Japanese journal of pharmacology, 1984, Volume: 35, Issue:2

    Topics: Animals; Baclofen; Enkephalin, Methionine; Male; Naloxone; Nerve Tissue Proteins; Neurons; Potassium; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Substance P

1984
Substance P, injected intrathecally, antagonizes the spinal antinociceptive effect of morphine, baclofen and noradrenaline.
    Neuropharmacology, 1984, Volume: 23, Issue:7A

    Topics: Afferent Pathways; Animals; Baclofen; Dose-Response Relationship, Drug; Eledoisin; Male; Morphine; Nociceptors; Norepinephrine; Physalaemin; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Synaptic Transmission

1984
Effect of neuroactive peptides on labeled 5-hydroxytryptamine release from rat spinal slices in vitro.
    Japanese journal of pharmacology, 1984, Volume: 35, Issue:4

    Topics: Animals; Baclofen; Enkephalin, Methionine; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Nerve Tissue Proteins; Potassium; Rats; Rats, Inbred Strains; Serotonin; Somatostatin; Spinal Cord; Substance P; Trigeminal Nucleus, Spinal

1984
GABAergic modulation of striatal peptide expression in rats and the alterations induced by dopamine antagonist treatment.
    Neuroscience letters, 1994, Oct-24, Volume: 180, Issue:2

    Topics: Animals; Baclofen; Benzazepines; Corpus Striatum; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enkephalins; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Haloperidol; In Situ Hybridization; Male; Muscimol; Protein Precursors; Rats; Rats, Wistar; Receptors, GABA; RNA, Messenger; Salicylamides; Substance P; Tachykinins; Vigabatrin

1994
Chronic (-)baclofen or CGP 36742 alters GABAB receptor sensitivity in rat brain and spinal cord.
    Neuroreport, 1995, Jan-26, Volume: 6, Issue:2

    Topics: Amino Acids; Analysis of Variance; Animals; Baclofen; Evoked Potentials; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Neuronal Plasticity; Olfactory Pathways; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-B; Spinal Cord; Substance P

1995
Gamma-aminobutyric acidB, but not gamma-aminobutyric acidA receptor activation, inhibits electrically evoked substance P-like immunoreactivity release from the rat spinal cord in vitro.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:3

    Topics: Animals; Baclofen; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Neurotransmitter Uptake Inhibitors; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Substance P

1993
Peripheral GABAA receptor-mediated effects of sodium valproate on dural plasma protein extravasation to substance P and trigeminal stimulation.
    British journal of pharmacology, 1995, Volume: 116, Issue:1

    Topics: Animals; Baclofen; Blood Pressure; Capillary Permeability; Capsaicin; Dura Mater; Electric Stimulation; Extravasation of Diagnostic and Therapeutic Materials; GABA Agents; GABA Agonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Heart Rate; Iodine Radioisotopes; Male; Muscimol; Neuritis; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Serum Albumin, Bovine; Substance P; Trigeminal Ganglion; Valproic Acid

1995
GABA, glutamate and substance P-like immunoreactivity release: effects of novel GABAB antagonists.
    British journal of pharmacology, 1996, Volume: 118, Issue:5

    Topics: Animals; Baclofen; Benzoates; Benzylamines; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Isonicotinic Acids; Male; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Rats; Rats, Wistar; Receptors, GABA-B; Spinal Nerve Roots; Stereoisomerism; Substance P

1996
Tachykinins may modify spontaneous epileptiform activity in the rat entorhinal cortex in vitro by activating GABAergic inhibition.
    Neuroscience, 1998, Volume: 83, Issue:4

    Topics: Animals; Baclofen; Bicuculline; Entorhinal Cortex; Epilepsy; Evoked Potentials; In Vitro Techniques; Male; Membrane Potentials; Neurokinin A; Neurokinin B; Neurons; Peptide Fragments; Phosphinic Acids; Propanolamines; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Receptors, GABA-B; Substance P; Synapses; Tachykinins

1998
A pharmacologic analysis of mechanical hyperalgesia in streptozotocin/diabetic rats.
    Pain, 1998, Volume: 76, Issue:1-2

    Topics: Animals; Baclofen; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dizocilpine Maleate; GABA Agonists; GABA-B Receptor Agonists; Hyperalgesia; Indoles; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Physical Stimulation; Pressure; Rats; Rats, Wistar; Sciatic Nerve; Spinal Cord; Substance P

1998
Substance P release in the dorsal horn assessed by receptor internalization: NMDA receptors counteract a tonic inhibition by GABA(B) receptors.
    The European journal of neuroscience, 1999, Volume: 11, Issue:2

    Topics: Animals; Baclofen; Dizocilpine Maleate; Down-Regulation; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Muscimol; Neural Inhibition; Organ Culture Techniques; Rats; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P

1999
Neuropeptide-mediated facilitation and inhibition of sensory inputs and spinal cord reflexes in the lamprey.
    Journal of neurophysiology, 1999, Volume: 81, Issue:4

    Topics: Action Potentials; Analgesics; Animals; Baclofen; Behavior, Animal; Bombesin; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; GABA Agonists; Lampreys; Male; N-Methylaspartate; Neurons, Afferent; Neuropeptide Y; Reflex; Spinal Cord; Substance P; Swimming; Synapses

1999
Electrophysiological properties of anatomically identified ventral pallidal neurons in rat brain slices.
    Annals of the New York Academy of Sciences, 1999, Jun-29, Volume: 877

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Baclofen; Dopamine; Electrophysiology; Enkephalin, Methionine; Evoked Potentials; Globus Pallidus; In Vitro Techniques; Microscopy, Confocal; Muscarine; Neurons; Rats; Serotonin; Substance P

1999
Biophysical properties and responses to neurotransmitters of petrosal and geniculate ganglion neurons innervating the tongue.
    Journal of neurophysiology, 2000, Volume: 84, Issue:3

    Topics: Acetylcholine; Action Potentials; Animals; Baclofen; Carotid Sinus; Cell Separation; Dose-Response Relationship, Drug; Female; Fluorescent Dyes; GABA Agonists; gamma-Aminobutyric Acid; Ganglia, Sensory; Geniculate Ganglion; In Vitro Techniques; Muscimol; Neurons; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Reaction Time; Stilbamidines; Substance P; Tongue

2000
Effects of baclofen on colon inflammation-induced Fos, CGRP and SP expression in spinal cord and brainstem.
    Brain research, 2001, Jan-19, Volume: 889, Issue:1-2

    Topics: Animals; Baclofen; Brain Stem; Calcitonin Gene-Related Peptide; Cell Count; Colitis; Colon; GABA Agonists; Gene Expression Regulation; Genes, fos; Immunohistochemistry; Kinetics; Male; Medulla Oblongata; Mustard Plant; Neurons; Plant Extracts; Plant Oils; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

2001
Pruritus after intrathecal baclofen withdrawal: A retrospective study.
    Archives of physical medicine and rehabilitation, 2005, Volume: 86, Issue:3

    Topics: Baclofen; GABA Agonists; Humans; Incidence; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Pruritus; Retrospective Studies; Substance P; Substance Withdrawal Syndrome

2005
Postsynaptic actions of substance P on rat periaqueductal grey neurons in vitro.
    Neuropharmacology, 2005, Volume: 49, Issue:5

    Topics: Action Potentials; Animals; Baclofen; Electrophysiology; Enkephalin, Methionine; Excitatory Postsynaptic Potentials; Female; GABA Agonists; In Vitro Techniques; Male; Membrane Potentials; Neurokinin-1 Receptor Antagonists; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Opioid, mu; Receptors, Somatostatin; Receptors, Tachykinin; Substance P

2005
Secondary hyperalgesia in the monoarthritic rat is mediated by GABAB and NK1 receptors of spinal dorsal horn neurons: a behavior and c-fos study.
    Neuroscience, 2006, Sep-15, Volume: 141, Issue:4

    Topics: Animals; Arthritis; Baclofen; Behavior, Animal; Drug Interactions; Freund's Adjuvant; GABA Agonists; Gene Expression; Hyperalgesia; Immunohistochemistry; Male; Pain Measurement; Pain Threshold; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Substance P

2006
Substance P inhibits GABAB receptor signalling in the ventral tegmental area.
    The Journal of physiology, 2010, May-01, Volume: 588, Issue:Pt 9

    Topics: Animals; Baclofen; Chelating Agents; Dopamine; Egtazic Acid; Electrophysiology; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Signal Transduction; Substance P; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2010
Src family kinases mediate the inhibition of substance P release in the rat spinal cord by μ-opioid receptors and GABA(B) receptors, but not α2 adrenergic receptors.
    The European journal of neuroscience, 2010, Volume: 32, Issue:6

    Topics: Animals; Baclofen; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, GABA-B; Receptors, Opioid, mu; Spinal Cord; src-Family Kinases; Substance P

2010
Gi-coupled γ-aminobutyric acid-B receptors cross-regulate phospholipase C and calcium in airway smooth muscle.
    American journal of respiratory cell and molecular biology, 2011, Volume: 45, Issue:6

    Topics: Baclofen; Bradykinin; Calcium; Cells, Cultured; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Humans; Inositol Phosphates; Lung; Muscimol; Muscle Contraction; Muscle, Smooth; Myocytes, Smooth Muscle; Receptors, GABA-A; Receptors, GABA-B; Substance P; Type C Phospholipases; Xanthenes

2011
The indirect γ-aminobutyric acid (GABA) receptor agonist gabaculine-induced loss of the righting reflex may inhibit the descending analgesic pathway.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 198

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Baclofen; Cyclohexanecarboxylic Acids; Dexmedetomidine; GABA Agonists; Ganglia, Spinal; Male; Mice; Morphine; Muscimol; Neural Pathways; Neurons; Pain Measurement; Rats; Reflex, Righting; Signal Transduction; Spinal Cord; Substance P

2020