substance p has been researched along with baclofen in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (62.90) | 18.7374 |
| 1990's | 14 (22.58) | 18.2507 |
| 2000's | 5 (8.06) | 29.6817 |
| 2010's | 3 (4.84) | 24.3611 |
| 2020's | 1 (1.61) | 2.80 |
| Authors | Studies |
|---|---|
| Konishi, S; Otsuka, M | 1 |
| Costa, E; Guidotti, A; Naik, SR | 1 |
| Burgis, V; Edwards, JD; Frederickson, RC; Harrell, CE | 1 |
| Aghajanian, GK; Guyenet, PG | 1 |
| Biswas, B; Carlsson, A; Lindqvist, M | 1 |
| Yau, WM | 1 |
| Fotherby, KJ; Morrish, NJ; Ryall, RW | 1 |
| Ben-Ari, Y; Henry, JL | 1 |
| Phillis, JW | 1 |
| Del Bianco, E; Maggi, CA; Santicioli, P; Tramontana, M | 1 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Mauborgne, A; Pohl, M | 1 |
| Jones, AJ; Keen, P; Ray, NJ | 1 |
| Couture, R; De Champlain, J; Hasséssian, H; Prat, A | 1 |
| Taniyama, K | 1 |
| Persson, B; Rubenson, A; Sillén, U | 1 |
| Robertson, G; Sawynok, J | 1 |
| Hwang, AS; Wilcox, GL | 2 |
| Akagi, H; Yanagisawa, M | 1 |
| Beal, MF; Ferrante, RJ; Kowall, NW; Martin, JB; Swartz, KJ | 1 |
| Aanonsen, LM; Wilcox, GL | 1 |
| Inoki, R; Lin, JG; Tsai, HY | 1 |
| Barnes, PJ; Belvisi, MG; Ichinose, M | 1 |
| Sawynok, J | 1 |
| Tsai, HY | 2 |
| Chahl, LA; Walker, SB | 1 |
| Kudo, T | 1 |
| Kanazawa, I; Yoshida, M | 1 |
| Ganten, D; Rettig, R; Rockhold, RW; Unger, T; Yukimura, T | 1 |
| Sears, M; Soloway, MR; Stjernschantz, J | 1 |
| Otsuka, M; Yanagisawa, M | 1 |
| Ajioka, H; Fukuda, H; Kudo, Y | 1 |
| Kato, T; Nagatsu, T; Togari, A | 1 |
| Abe, H; Ogata, N | 2 |
| Fujiwara, M; Muramatsu, I; Sakakibara, Y; Ueda, N | 1 |
| Fujisawa, K; Ito, Y | 1 |
| Havlicek, V; Kato, N; LaBella, FS; Sawynok, J | 1 |
| Couture, R; Cuello, AC | 1 |
| Leo, A; Marano, E; Steardo, L | 1 |
| Moochhala, SM; Pillay, DJ; Sawynok, J | 1 |
| Inoki, R; Iwatsubo, K; Maeda, S; Tsai, HY | 1 |
| Jenner, P; Jolkkonen, J; Marsden, CD | 1 |
| Bowery, NG; Constanti, A; Libri, V; Malcangio, M; Teoh, H | 1 |
| Bowery, NG; Malcangio, M | 1 |
| Ayata, C; Cutrer, FM; Lee, WS; Limmroth, V; Moskowitz, MA; Waeber, C; Yu, X | 1 |
| Bowery, NG; Malcangio, M; Teoh, H | 1 |
| Cody, C; Jones, RS; Maubach, KA | 1 |
| Malcangio, M; Tomlinson, DR | 1 |
| Bunnett, NW; Grady, EF; Marvizón, JC; Mayer, EA; Stefani, E | 1 |
| Grillner, S; Parker, D; Svensson, E; Ullström, M | 1 |
| Bengtson, CP; Osborne, PB | 1 |
| Bradley, RM; Koga, T | 1 |
| Lu, Y; Westlund, KN | 1 |
| Ben Smail, D; Bussel, B; Denys, P; Hugeron, C | 1 |
| Drew, GM; Mitchell, VA; Vaughan, CW | 1 |
| Castro, AR; Lima, D; Pinto, M; Tavares, I | 1 |
| Hjelmstad, GO; Margolis, EB; Xia, YF | 1 |
| Chen, W; Marvizón, JC; Zhang, G | 1 |
| Emala, CW; Masaki, E; Mizuta, F; Mizuta, K; Panettieri, RA; Xu, D | 1 |
| Doi, M; Irifune, M; Kanematsu, T; Morioka, N; Mukai, A; Nakata, Y; Ogawa, Y; Oue, K; Sakai, N; Shimizu, Y; Yoshida, M | 1 |
1 review(s) available for substance p and baclofen
| Article | Year |
|---|---|
[GABAergic neurons in the mammalian intestine].
Topics: Animals; Autonomic Fibers, Postganglionic; Autoradiography; Baclofen; Calcium; Digestive System; gamma-Aminobutyric Acid; Gastrointestinal Motility; Glutamate Decarboxylase; Guinea Pigs; Histocytochemistry; Humans; In Vitro Techniques; Muscimol; Myenteric Plexus; Potassium; Rabbits; Rats; Receptors, GABA-A; Substance P; Synaptic Transmission; Vasoactive Intestinal Peptide | 1985 |
1 trial(s) available for substance p and baclofen
| Article | Year |
|---|---|
Efficacy of baclofen in trigeminal neuralgia and some other painful conditions. A clinical trial.
Topics: Adult; Amputation Stumps; Baclofen; Carbamazepine; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Neuralgia; Phenytoin; Radiculopathy; Substance P; Tabes Dorsalis; Trigeminal Neuralgia | 1984 |
60 other study(ies) available for substance p and baclofen
| Article | Year |
|---|---|
Substance P and excitatory transmitter of primary sensory neurons.
Topics: Amino Acids; Animals; Animals, Newborn; Baclofen; Dose-Response Relationship, Drug; Drug Interactions; Glutamates; In Vitro Techniques; Membrane Potentials; Motor Neurons; Neurons; Neurons, Afferent; Neurotransmitter Agents; Picrotoxin; Rats; Reflex; Spinal Cord; Spinal Nerve Roots; Stimulation, Chemical; Substance P; Synapses; Synaptic Transmission | 1976 |
Central GABA receptor agonists: comparison of muscimol and baclofen.
Topics: Aminobutyrates; Animals; Anticonvulsants; Baclofen; Cerebellum; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Harmaline; Isoniazid; Male; Motor Activity; Muscle Tonus; Mycotoxins; Oxazoles; Phenobarbital; Quaternary Ammonium Compounds; Rats; Receptors, Drug; Strychnine; Substance P | 1976 |
Dual actions of substance P on nociception: possible role of endogenous opioids.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Mice; Naloxone; Nociceptors; Receptors, Opioid; Structure-Activity Relationship; Substance P | 1978 |
ACh, substance P and met-enkephalin in the locus coeruleus: pharmacological evidence for independent sites of action.
Topics: Acetylcholine; Animals; Baclofen; Endorphins; Enkephalins; Locus Coeruleus; Male; Naloxone; Parasympatholytics; Parasympathomimetics; Rats; Receptors, Cholinergic; Substance P; Synaptic Transmission | 1979 |
Influence of GABA and GABA-like drugs on monoaminergic mechanisms.
Topics: 5-Hydroxytryptophan; Aminobutyrates; Animals; Baclofen; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraventricular; Norepinephrine; Rats; Receptors, Drug; Serotonin; Substance P | 1977 |
Effect of substance P on intestinal muscle.
Topics: Acetylcholine; Animals; Atropine; Autonomic Fibers, Postganglionic; Baclofen; Ceruletide; Dose-Response Relationship, Drug; Electrophysiology; Female; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Kinetics; Muscle, Smooth; Neurons; Substance P; Tetrodotoxin | 1978 |
Is Lioresal (Baclofen) an antagonist of substance P?
Topics: Aminobutyrates; Animals; Baclofen; Gastrointestinal Motility; Guinea Pigs; Ileum; Substance P | 1976 |
Actions of the p-chlorophenyl derivative of GABA, Lioresal, on nociceptive and non-nociceptive units in the spinal cord of the cat.
Topics: Aminobutyrates; Animals; Baclofen; Cats; Depression, Chemical; Spinal Cord; Substance P | 1976 |
Is beta-(4-chlorophenyl)-GABA a specific antagonist of substance P on cerebral cortical neurons?
Topics: Acetylcholine; Action Potentials; Aminobutyrates; Animals; Baclofen; Cerebral Cortex; Glutamates; Male; Neurons; Pyramidal Tracts; Rats; Stimulation, Chemical; Substance P | 1976 |
Adenosine inhibits action potential-dependent release of calcitonin gene-related peptide- and substance P-like immunoreactivities from primary afferents in rat spinal cord.
Topics: Action Potentials; Adenosine; Animals; Baclofen; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; In Vitro Techniques; Male; Neurons, Afferent; Rats; Rats, Wistar; Spinal Cord; Substance P; Tetrodotoxin | 1992 |
gamma-Aminobutyric acid, through GABAA receptors, inhibits the potassium-stimulated release of calcitonin gene-related peptide- but not that of substance P-like material from rat spinal cord slices.
Topics: Animals; Baclofen; Bicuculline; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Substance P | 1992 |
GABAB receptor modulation of the release of substance P from capsaicin-sensitive neurones in the rat trachea in vitro.
Topics: Animals; Baclofen; Bicuculline; Capsaicin; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neurons; Potassium; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substance P; Taurine; Trachea | 1991 |
Regulation of cardiovascular sympathetic neurons by substance P and gamma-aminobutyric acid in the rat spinal cord.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Capsaicin; Cardiovascular Physiological Phenomena; Cardiovascular System; Catecholamines; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Heart Rate; Injections, Spinal; Male; Muscimol; Neurons; Neuropeptide Y; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Substance P; Sympathetic Nervous System | 1991 |
Central effects of baclofen on the L-dopa induced hyperactive urinary bladder of the rat.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Injections, Intraventricular; Levodopa; Male; Naloxone; Rats; Rats, Inbred Strains; Substance P; Urinary Bladder | 1985 |
Desensitization to substance P following intrathecal injection. A technique for investigating the role of substance P in nociception.
Topics: Animals; Baclofen; Injections, Spinal; Male; Morphine; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds; Substance P; Time Factors | 1985 |
Intradermal hypertonic saline-induced behavior as a nociceptive test in mice.
Topics: Animals; Anti-Inflammatory Agents; Baclofen; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intradermal; Injections, Spinal; Male; Mice; Morphine; Nalorphine; Pain; Pentazocine; Saline Solution, Hypertonic; Sodium Chloride; Spinal Cord; Substance P | 1986 |
GABAergic modulation of a substance P-mediated reflex of slow time course in the isolated rat spinal cord.
Topics: Animals; Baclofen; Bicuculline; Diazepam; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Substance P | 1987 |
Systemic approaches to modifying quinolinic acid striatal lesions in rats.
Topics: 2-Amino-5-phosphonovalerate; Allopurinol; Amino Acids; Animals; Antioxidants; Baclofen; Corpus Striatum; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Huntington Disease; Ketamine; Male; Neuropeptide Y; Nimodipine; Peptides; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Substance P; Taurine; Valine | 1988 |
Baclofen, gamma-aminobutyric acidB receptors and substance P in the mouse spinal cord.
Topics: Amino Acids; Amino Acids, Neutral; Analgesics; Animals; Baclofen; Dose-Response Relationship, Drug; Mice; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Substance P | 1989 |
Muscimol, gamma-aminobutyric acidA receptors and excitatory amino acids in the mouse spinal cord.
Topics: Analgesia; Animals; Aspartic Acid; Baclofen; Behavior, Animal; Bicuculline; Kainic Acid; Male; Mice; Muscimol; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, GABA-A; Spinal Cord; Substance P | 1989 |
Further evidence for possible analgesic mechanism of electroacupuncture: effects on neuropeptides and serotonergic neurons in rat spinal cord.
Topics: Acupuncture Therapy; Analgesia, Epidural; Animals; Baclofen; Electric Stimulation; Enkephalin, Methionine; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds; Serotonin; Spinal Cord; Substance P | 1989 |
Modulation of non-adrenergic, non-cholinergic neural bronchoconstriction in guinea-pig airways via GABAB-receptors.
Topics: Animals; Atropine; Autonomic Nervous System; Baclofen; Bicuculline; Blood Pressure; Bronchi; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Phentolamine; Propranolol; Receptors, GABA-A; Substance P; Time Factors; Vagus Nerve | 1989 |
GABAergic mechanisms in antinociception.
Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Analgesics; Animals; Baclofen; Bicuculline; Central Nervous System; gamma-Aminobutyric Acid; Isoxazoles; Mice; Muscimol; Pain; Rats; Stereoisomerism; Substance P; Synaptic Transmission; Vigabatrin | 1984 |
Effect of neuroactive peptides on labeled 5-hydroxytryptamine release from rat spinal cord.
Topics: Animals; Baclofen; beta-Endorphin; Endorphins; Enkephalin, Methionine; Male; Naloxone; Neuropeptides; Neurotensin; Pain; Rats; Rats, Inbred Strains; Secretory Rate; Serotonin; Somatostatin; Spinal Cord; Substance P | 1984 |
The mechanism of enhancement of the neurogenic oedema response by baclofen.
Topics: Animals; Baclofen; Blood Pressure; Drug Interactions; Edema; Exudates and Transudates; Injections, Intravenous; Injections, Subcutaneous; Male; Neurons; Rats; Serotonin; Substance P | 1980 |
[Mechanism of substance P-induced salivary secretion in the rat: effect of substance P on autonomic nervous system and prostaglandin synthesis (author's transl)].
Topics: Amylases; Animals; Autonomic Nervous System; Baclofen; Brain; Injections, Intravenous; Injections, Intraventricular; Male; Parasympatholytics; Prostaglandins; Prostaglandins E; Rats; Saliva; Stimulation, Chemical; Substance P; Sympatholytics; Sympathomimetics; Synaptosomes; Time Factors | 1980 |
Electrophysiological evidence for the existence of excitatory fibres in the caudato-nigral pathway in the cat.
Topics: Animals; Atropine; Baclofen; Cats; Caudate Nucleus; Electrophysiology; gamma-Aminobutyric Acid; Neural Pathways; Picrotoxin; Reaction Time; Substance P; Substantia Nigra | 1980 |
Blood pressure and heart rate responses to centrally administered substance P are increased in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Baclofen; Blood Pressure; Denervation; Dose-Response Relationship, Drug; Female; Heart Rate; Hypertension; Injections, Intraventricular; Male; Pressoreceptors; Rats; Substance P | 1980 |
The miotic effect of substance P on the isolated rabbit iris.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Baclofen; Dose-Response Relationship, Drug; Egtazic Acid; Indomethacin; Iris; Male; Miotics; Rabbits; Substance P | 1981 |
The effects of substance P and baclofen on motoneurones of isolated spinal cord of the newborn rat.
Topics: Action Potentials; Animals; Animals, Newborn; Baclofen; Calcium; gamma-Aminobutyric Acid; Glutamates; Glycine; In Vitro Techniques; Motor Neurons; Perfusion; Rats; Spinal Cord; Substance P | 1980 |
Antagonistic action of baclofen on substance P-induced depolarization in the isolated spinal cord of the frog.
Topics: Animals; Baclofen; Calcium; In Vitro Techniques; Magnesium; Rana catesbeiana; Spinal Cord; Substance P; Synaptic Transmission | 1981 |
Effect of substance P C-terminal heptapeptide on amylase release in rat parotid gland.
Topics: Amylases; Animals; Baclofen; Male; Parotid Gland; Peptide Fragments; Rats; Substance P | 1980 |
Further support for the postsynaptic action of substance P and its blockade with baclofen in neurons of the guinea-pig hypothalamus in vitro.
Topics: Acetylcholine; Action Potentials; Animals; Baclofen; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hypothalamus; In Vitro Techniques; Male; Neurons; Substance P; Synapses | 1981 |
Noncholinergic, nonadrenergic contraction and substance P in rabbit iris sphincter muscle.
Topics: Acetylcholine; Animals; Baclofen; Capsaicin; Cold Temperature; Electric Stimulation; Female; In Vitro Techniques; Iris; Male; Muscle Contraction; Rabbits; Reserpine; Substance P; Sympathectomy | 1981 |
The effects of substance P on smooth muscle cells and on neuro-effector transmission in the guinea-pig ileum.
Topics: Animals; Baclofen; Electrophysiology; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth; Neuroeffector Junction; Potassium Chloride; Substance P; Synaptic Transmission | 1982 |
Lack of effect of baclofen on substance P and somatostatin release from the spinal cord in vitro.
Topics: Animals; Baclofen; In Vitro Techniques; Male; Perfusion; Rats; Rats, Inbred Strains; Somatostatin; Spinal Cord; Substance P | 1982 |
Neuropharmacology in the brain slice: effects of substance P on neurons in the guinea-pig hypothalamus.
Topics: Animals; Baclofen; Electrophysiology; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hypothalamus; In Vitro Techniques; Male; Neurons; Substance P | 1982 |
Studies on the trigeminal antidromic vasodilatation and plasma extravasation in the rat.
Topics: Animals; Baclofen; Capillary Permeability; Cimetidine; Evoked Potentials; Female; Indomethacin; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Substance P; Sympatholytics; Trigeminal Nerve; Vasodilation | 1984 |
Further evidence for the possible relationship between neuropeptides and serotonergic neurones in rat spinal cord.
Topics: Animals; Baclofen; Enkephalin, Methionine; Male; Naloxone; Nerve Tissue Proteins; Neurons; Potassium; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Substance P | 1984 |
Substance P, injected intrathecally, antagonizes the spinal antinociceptive effect of morphine, baclofen and noradrenaline.
Topics: Afferent Pathways; Animals; Baclofen; Dose-Response Relationship, Drug; Eledoisin; Male; Morphine; Nociceptors; Norepinephrine; Physalaemin; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Synaptic Transmission | 1984 |
Effect of neuroactive peptides on labeled 5-hydroxytryptamine release from rat spinal slices in vitro.
Topics: Animals; Baclofen; Enkephalin, Methionine; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Nerve Tissue Proteins; Potassium; Rats; Rats, Inbred Strains; Serotonin; Somatostatin; Spinal Cord; Substance P; Trigeminal Nucleus, Spinal | 1984 |
GABAergic modulation of striatal peptide expression in rats and the alterations induced by dopamine antagonist treatment.
Topics: Animals; Baclofen; Benzazepines; Corpus Striatum; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enkephalins; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Haloperidol; In Situ Hybridization; Male; Muscimol; Protein Precursors; Rats; Rats, Wistar; Receptors, GABA; RNA, Messenger; Salicylamides; Substance P; Tachykinins; Vigabatrin | 1994 |
Chronic (-)baclofen or CGP 36742 alters GABAB receptor sensitivity in rat brain and spinal cord.
Topics: Amino Acids; Analysis of Variance; Animals; Baclofen; Evoked Potentials; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Neuronal Plasticity; Olfactory Pathways; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-B; Spinal Cord; Substance P | 1995 |
Gamma-aminobutyric acidB, but not gamma-aminobutyric acidA receptor activation, inhibits electrically evoked substance P-like immunoreactivity release from the rat spinal cord in vitro.
Topics: Animals; Baclofen; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Neurotransmitter Uptake Inhibitors; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Substance P | 1993 |
Peripheral GABAA receptor-mediated effects of sodium valproate on dural plasma protein extravasation to substance P and trigeminal stimulation.
Topics: Animals; Baclofen; Blood Pressure; Capillary Permeability; Capsaicin; Dura Mater; Electric Stimulation; Extravasation of Diagnostic and Therapeutic Materials; GABA Agents; GABA Agonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Heart Rate; Iodine Radioisotopes; Male; Muscimol; Neuritis; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Serum Albumin, Bovine; Substance P; Trigeminal Ganglion; Valproic Acid | 1995 |
GABA, glutamate and substance P-like immunoreactivity release: effects of novel GABAB antagonists.
Topics: Animals; Baclofen; Benzoates; Benzylamines; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Isonicotinic Acids; Male; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Rats; Rats, Wistar; Receptors, GABA-B; Spinal Nerve Roots; Stereoisomerism; Substance P | 1996 |
Tachykinins may modify spontaneous epileptiform activity in the rat entorhinal cortex in vitro by activating GABAergic inhibition.
Topics: Animals; Baclofen; Bicuculline; Entorhinal Cortex; Epilepsy; Evoked Potentials; In Vitro Techniques; Male; Membrane Potentials; Neurokinin A; Neurokinin B; Neurons; Peptide Fragments; Phosphinic Acids; Propanolamines; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Receptors, GABA-B; Substance P; Synapses; Tachykinins | 1998 |
A pharmacologic analysis of mechanical hyperalgesia in streptozotocin/diabetic rats.
Topics: Animals; Baclofen; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dizocilpine Maleate; GABA Agonists; GABA-B Receptor Agonists; Hyperalgesia; Indoles; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Physical Stimulation; Pressure; Rats; Rats, Wistar; Sciatic Nerve; Spinal Cord; Substance P | 1998 |
Substance P release in the dorsal horn assessed by receptor internalization: NMDA receptors counteract a tonic inhibition by GABA(B) receptors.
Topics: Animals; Baclofen; Dizocilpine Maleate; Down-Regulation; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Muscimol; Neural Inhibition; Organ Culture Techniques; Rats; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P | 1999 |
Neuropeptide-mediated facilitation and inhibition of sensory inputs and spinal cord reflexes in the lamprey.
Topics: Action Potentials; Analgesics; Animals; Baclofen; Behavior, Animal; Bombesin; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; GABA Agonists; Lampreys; Male; N-Methylaspartate; Neurons, Afferent; Neuropeptide Y; Reflex; Spinal Cord; Substance P; Swimming; Synapses | 1999 |
Electrophysiological properties of anatomically identified ventral pallidal neurons in rat brain slices.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Baclofen; Dopamine; Electrophysiology; Enkephalin, Methionine; Evoked Potentials; Globus Pallidus; In Vitro Techniques; Microscopy, Confocal; Muscarine; Neurons; Rats; Serotonin; Substance P | 1999 |
Biophysical properties and responses to neurotransmitters of petrosal and geniculate ganglion neurons innervating the tongue.
Topics: Acetylcholine; Action Potentials; Animals; Baclofen; Carotid Sinus; Cell Separation; Dose-Response Relationship, Drug; Female; Fluorescent Dyes; GABA Agonists; gamma-Aminobutyric Acid; Ganglia, Sensory; Geniculate Ganglion; In Vitro Techniques; Muscimol; Neurons; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Reaction Time; Stilbamidines; Substance P; Tongue | 2000 |
Effects of baclofen on colon inflammation-induced Fos, CGRP and SP expression in spinal cord and brainstem.
Topics: Animals; Baclofen; Brain Stem; Calcitonin Gene-Related Peptide; Cell Count; Colitis; Colon; GABA Agonists; Gene Expression Regulation; Genes, fos; Immunohistochemistry; Kinetics; Male; Medulla Oblongata; Mustard Plant; Neurons; Plant Extracts; Plant Oils; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 2001 |
Pruritus after intrathecal baclofen withdrawal: A retrospective study.
Topics: Baclofen; GABA Agonists; Humans; Incidence; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Pruritus; Retrospective Studies; Substance P; Substance Withdrawal Syndrome | 2005 |
Postsynaptic actions of substance P on rat periaqueductal grey neurons in vitro.
Topics: Action Potentials; Animals; Baclofen; Electrophysiology; Enkephalin, Methionine; Excitatory Postsynaptic Potentials; Female; GABA Agonists; In Vitro Techniques; Male; Membrane Potentials; Neurokinin-1 Receptor Antagonists; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Opioid, mu; Receptors, Somatostatin; Receptors, Tachykinin; Substance P | 2005 |
Secondary hyperalgesia in the monoarthritic rat is mediated by GABAB and NK1 receptors of spinal dorsal horn neurons: a behavior and c-fos study.
Topics: Animals; Arthritis; Baclofen; Behavior, Animal; Drug Interactions; Freund's Adjuvant; GABA Agonists; Gene Expression; Hyperalgesia; Immunohistochemistry; Male; Pain Measurement; Pain Threshold; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Substance P | 2006 |
Substance P inhibits GABAB receptor signalling in the ventral tegmental area.
Topics: Animals; Baclofen; Chelating Agents; Dopamine; Egtazic Acid; Electrophysiology; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Signal Transduction; Substance P; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2010 |
Src family kinases mediate the inhibition of substance P release in the rat spinal cord by μ-opioid receptors and GABA(B) receptors, but not α2 adrenergic receptors.
Topics: Animals; Baclofen; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, GABA-B; Receptors, Opioid, mu; Spinal Cord; src-Family Kinases; Substance P | 2010 |
Gi-coupled γ-aminobutyric acid-B receptors cross-regulate phospholipase C and calcium in airway smooth muscle.
Topics: Baclofen; Bradykinin; Calcium; Cells, Cultured; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Humans; Inositol Phosphates; Lung; Muscimol; Muscle Contraction; Muscle, Smooth; Myocytes, Smooth Muscle; Receptors, GABA-A; Receptors, GABA-B; Substance P; Type C Phospholipases; Xanthenes | 2011 |
The indirect γ-aminobutyric acid (GABA) receptor agonist gabaculine-induced loss of the righting reflex may inhibit the descending analgesic pathway.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Baclofen; Cyclohexanecarboxylic Acids; Dexmedetomidine; GABA Agonists; Ganglia, Spinal; Male; Mice; Morphine; Muscimol; Neural Pathways; Neurons; Pain Measurement; Rats; Reflex, Righting; Signal Transduction; Spinal Cord; Substance P | 2020 |