Page last updated: 2024-08-23

substance p and (2s,3s)-2-phenyl-3-((5-trifluoromethoxy-2-methoxy)benzylamino)piperidine

substance p has been researched along with (2s,3s)-2-phenyl-3-((5-trifluoromethoxy-2-methoxy)benzylamino)piperidine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bryce, DK; Coffman, KJ; Crawford, RT; Gohda, Y; Lowe, JA; McLean, S; Nagahisa, A; Nakane, M; Rosen, TJ; Tsuchiya, M1
Bryce, DK; Crawford, RT; DePasquale, M; Fossa, A; Ganong, A; Heym, J; McLean, S; Morrone, J; Nagahisa, A; Reynolds, LS; Rosen, T; Schmidt, AW; Seymour, PA; Tsuchiya, M; Watson, J; Zorn, S1
Brené, S; Lindefors, N; Zachrisson, O1
Black, LS; D'Angelo, R; Dalby, PL; Gesztesi, Z; MacLean, D; Scuderi, PE; Wender, RH; White, PF; Wright, W1
Hu, C; Jiang, X; King, KA; Piedimonte, G; Rodriguez, MM; Romaguera, R1
Adkins, B; Auais, A; Napchan, G; Piedimonte, G1

Trials

1 trial(s) available for substance p and (2s,3s)-2-phenyl-3-((5-trifluoromethoxy-2-methoxy)benzylamino)piperidine

ArticleYear
Substance P (Neurokinin-1) antagonist prevents postoperative vomiting after abdominal hysterectomy procedures.
    Anesthesiology, 2000, Volume: 93, Issue:4

    Topics: Administration, Oral; Adult; Antiemetics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hysterectomy; Injections, Intravenous; Neurokinin-1 Receptor Antagonists; Ondansetron; Piperidines; Placebos; Postoperative Nausea and Vomiting; Preanesthetic Medication; Risk Factors; Serotonin Antagonists; Substance P

2000

Other Studies

5 other study(ies) available for substance p and (2s,3s)-2-phenyl-3-((5-trifluoromethoxy-2-methoxy)benzylamino)piperidine

ArticleYear
Synthesis and structure-activity relationships of CP-122,721, a second-generation NK-1 receptor antagonist.
    Bioorganic & medicinal chemistry letters, 1998, Feb-03, Volume: 8, Issue:3

    Topics: Animals; Capsaicin; Cell Line; Guinea Pigs; Humans; Motor Activity; Neurokinin-1 Receptor Antagonists; Piperidines; Structure-Activity Relationship

1998
Characterization of CP-122,721; a nonpeptide antagonist of the neurokinin NK1 receptor.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:2

    Topics: Animals; Blood Pressure; Capillary Permeability; Dogs; Female; Guinea Pigs; Humans; Locus Coeruleus; Male; Motor Activity; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Salivation; Substance P

1996
A tachykinin NK1 receptor antagonist, CP-122,721-1, attenuates kainic acid-induced seizure activity.
    Brain research. Molecular brain research, 1998, Oct-01, Volume: 60, Issue:2

    Topics: Animals; Cell Survival; Corpus Striatum; Hippocampus; Kainic Acid; Kinetics; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures; Substance P; Tachykinins; Time Factors; Transcription, Genetic

1998
Exaggerated neurogenic inflammation and substance P receptor upregulation in RSV-infected weanling rats.
    American journal of respiratory cell and molecular biology, 2001, Volume: 24, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Body Weight; Cell Line; DNA Primers; Humans; Immunoenzyme Techniques; Lung; Neurogenic Inflammation; Neuropeptides; Piperidines; Rats; Rats, Inbred F344; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Vasoactive Intestinal Peptide; Respiratory Syncytial Virus Infections; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Up-Regulation

2001
Immunomodulatory effects of sensory nerves during respiratory syncytial virus infection in rats.
    American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 285, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Asthma; Leukocyte Count; Lung; Lymphocyte Subsets; Male; Monocytes; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Piperidines; Pneumonia, Viral; Rats; Rats, Inbred F344; Receptors, Neurokinin-1; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Specific Pathogen-Free Organisms; Substance P

2003