substance p, sar(9)-met(o2)(11)- and indomethacin

substance p, sar(9)-met(o2)(11)- has been researched along with indomethacin in 2 studies

Compound Research Comparison

Studies (substance p, sar(9)-met(o2)(11)-)	Trials (substance p, sar(9)-met(o2)(11)-)	Recent Studies (post-2010) (substance p, sar(9)-met(o2)(11)-)	Studies (indomethacin)	Trials (indomethacin)	Recent Studies (post-2010) (indomethacin)
151	0	6	29,527	1,838	3,396

Protein Interaction Comparison

Protein	Taxonomy	indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2	Macaca fascicularis (crab-eating macaque)	1000
Prostaglandin-H2 D-isomerase	Mus musculus (house mouse)	1.1
Multidrug resistance-associated protein 4	Homo sapiens (human)	5.8
Prostaglandin G/H synthase 1	Bos taurus (cattle)	0.9994
Prostaglandin G/H synthase 2	Bos taurus (cattle)	0.7764
Cytochrome c oxidase subunit 2	Homo sapiens (human)	0.34
Prostaglandin G/H synthase 1	Ovis aries (sheep)	0.5605
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	0.004
Interleukin-8	Homo sapiens (human)	0.05
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	0.004
Aldo-keto reductase family 1 member B1	Homo sapiens (human)	6
Aldo-keto reductase family 1 member B1	Bos taurus (cattle)	5
Prostaglandin G/H synthase 1	Mus musculus (house mouse)	0.011
Prostaglandin G/H synthase 1	Homo sapiens (human)	0.4848
Sodium- and chloride-dependent GABA transporter 1	Rattus norvegicus (Norway rat)	0.2
Thromboxane-A synthase	Homo sapiens (human)	0.1
Indoleamine 2,3-dioxygenase 1	Mus musculus (house mouse)	0.082
Nitric oxide synthase, inducible	Mus musculus (house mouse)	4.5
Substance-P receptor	Cavia porcellus (domestic guinea pig)	5.7
Sodium- and chloride-dependent GABA transporter 2	Rattus norvegicus (Norway rat)	0.2
Sodium- and chloride-dependent GABA transporter 3	Rattus norvegicus (Norway rat)	0.2
Prostaglandin G/H synthase 2	Homo sapiens (human)	1.5128
Prostaglandin G/H synthase 2	Rattus norvegicus (Norway rat)	0.5504
Aldo-keto reductase family 1 member C3	Homo sapiens (human)	3.4486
Sodium- and chloride-dependent betaine transporter	Rattus norvegicus (Norway rat)	0.2
C-X-C chemokine receptor type 3	Homo sapiens (human)	0.05
Aldo-keto reductase family 1 member C2	Homo sapiens (human)	8.97
Prostaglandin G/H synthase 2	Ovis aries (sheep)	3.4647
Prostaglandin G/H synthase 2	Mus musculus (house mouse)	0.4233
Solute carrier family 22 member 6	Homo sapiens (human)	3
Sigma intracellular receptor 2	Rattus norvegicus (Norway rat)	0.49
Rho-associated protein kinase 2	Rattus norvegicus (Norway rat)	7.7
Prostaglandin G/H synthase 1	Rattus norvegicus (Norway rat)	0.5461
P2Y purinoceptor 12	Rattus norvegicus (Norway rat)	0.96

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Giachetti, A; Maggi, CA; Santicioli, P; Zagorodnyuk, V	1
Bertrand, PP; Bian, XC; Bornstein, JC; Furness, JB	1

Other Studies

2 other study(ies) available for substance p, sar(9)-met(o2)(11)- and indomethacin

Article	Year
Evidence that tachykinin NK1 and NK2 receptors mediate non-adrenergic non-cholinergic excitation and contraction in the circular muscle of guinea-pig duodenum. British journal of pharmacology, 1995, Volume: 115, Issue:2 Topics: Action Potentials; Adenosine Diphosphate; Animals; Apamin; Arginine; Atropine; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Guanethidine; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neuromuscular Junction; Nifedipine; Nitroarginine; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Physalaemin; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Suramin; Thionucleotides	1995
Evidence for functional NK1-tachykinin receptors on motor neurones supplying the circular muscle of guinea-pig small and large intestine. Neurogastroenterology and motility, 2000, Volume: 12, Issue:4 Topics: Animals; Colon; Duodenum; Enzyme Inhibitors; Guinea Pigs; Ileum; Immunohistochemistry; In Vitro Techniques; Indomethacin; Motor Neurons; Muscle, Smooth; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Pyrrolidonecarboxylic Acid; Receptors, Neurokinin-1; Substance P	2000

Article

Year

Evidence that tachykinin NK1 and NK2 receptors mediate non-adrenergic non-cholinergic excitation and contraction in the circular muscle of guinea-pig duodenum.

British journal of pharmacology, 1995, Volume: 115, Issue:2

Topics: Action Potentials; Adenosine Diphosphate; Animals; Apamin; Arginine; Atropine; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Guanethidine; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neuromuscular Junction; Nifedipine; Nitroarginine; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Physalaemin; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Suramin; Thionucleotides

1995

Evidence for functional NK1-tachykinin receptors on motor neurones supplying the circular muscle of guinea-pig small and large intestine.

Neurogastroenterology and motility, 2000, Volume: 12, Issue:4

Topics: Animals; Colon; Duodenum; Enzyme Inhibitors; Guinea Pigs; Ileum; Immunohistochemistry; In Vitro Techniques; Indomethacin; Motor Neurons; Muscle, Smooth; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Pyrrolidonecarboxylic Acid; Receptors, Neurokinin-1; Substance P

2000